| Year |
Citation |
Score |
| 2021 |
Williams LM, Sridhar S, Samaroo J, Peart J, Adindu EK, Addanki A, DiRusso CJ, Aguirre Carrión PJ, Rodriguez-Sastre N, Siggers T, Gilmore TD. Comparison of NF-κB from the protists Capsaspora owczarzaki and Acanthoeca spectabilis reveals extensive evolutionary diversification of this transcription factor. Communications Biology. 4: 1404. PMID 34916615 DOI: 10.1038/s42003-021-02924-2 |
0.445 |
|
| 2021 |
Gilmore TD. NF-κB and Human Cancer: What Have We Learned over the Past 35 Years? Biomedicines. 9. PMID 34440093 DOI: 10.3390/biomedicines9080889 |
0.408 |
|
| 2021 |
Aguirre Carrión PJ, Williams LM, Gilmore TD. Molecular and Biochemical Approaches to Study the Evolution of NF-κB Signaling in Basal Metazoans. Methods in Molecular Biology (Clifton, N.J.). 2366: 67-91. PMID 34236633 DOI: 10.1007/978-1-0716-1669-7_5 |
0.319 |
|
| 2020 |
Williams LM, Gilmore TD. Looking down on NF-κB. Molecular and Cellular Biology. PMID 32393609 DOI: 10.1128/Mcb.00104-20 |
0.514 |
|
| 2019 |
Williams LM, Inge MM, Mansfield KM, Rasmussen A, Afghani J, Agrba M, Albert C, Andersson C, Babaei M, Babaei M, Bagdasaryants A, Bonilla A, Browne A, Carpenter S, Chen T, ... ... Gilmore TD, et al. Transcription factor NF-κB in a basal metazoan, the sponge, has conserved and unique sequences, activities, and regulation. Developmental and Comparative Immunology. 103559. PMID 31751628 DOI: 10.1016/J.Dci.2019.103559 |
0.521 |
|
| 2019 |
Babaei M, Liu Y, Wuerzberger-Davis SM, McCaslin EZ, DiRusso CJ, Yeo AT, Kagermazova L, Miyamoto S, Gilmore TD. CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein. Plos One. 14: e0222588. PMID 31553754 DOI: 10.1371/Journal.Pone.0222588 |
0.528 |
|
| 2019 |
Shaffer R, DeMaria AH, Kagermazova L, Liu Y, Babaei M, Penix S, Cervantes A, Jehle S, Makowski L, Gilmore TD, Whitty A, Allen KN. A Central Region of NEMO is Required for IKKβ-Induced Conformational Change and for Signal Propagation. Biochemistry. PMID 31145594 DOI: 10.1021/Acs.Biochem.8B01316 |
0.437 |
|
| 2018 |
Brennan JJ, Gilmore TD. Evolutionary Origins of Toll-like Receptor Signaling. Molecular Biology and Evolution. PMID 29590394 DOI: 10.1093/Molbev/Msy050 |
0.316 |
|
| 2017 |
Mansfield KM, Carter NM, Nguyen L, Cleves PA, Alshanbayeva A, Williams LM, Crowder C, Penvose AR, Finnerty JR, Weis VM, Siggers TW, Gilmore TD. Transcription factor NF-κB is modulated by symbiotic status in a sea anemone model of cnidarian bleaching. Scientific Reports. 7: 16025. PMID 29167511 DOI: 10.1038/S41598-017-16168-W |
0.515 |
|
| 2017 |
Brennan JJ, Messerschmidt JL, Williams LM, Matthews BJ, Reynoso M, Gilmore TD. Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109290 DOI: 10.1073/Pnas.1711530114 |
0.381 |
|
| 2017 |
Williams LM, Fuess LE, Brennan JJ, Mansfield KM, Salas-Rodriguez E, Welsh J, Awtry J, Banic S, Chacko C, Chezian A, Dowers D, Estrada F, Hsieh YH, Kang J, Li W, ... ... Gilmore TD, et al. A conserved toll-like receptor-to-NF-κB signaling pathway in the endangered coral Orbicella faveolata. Developmental and Comparative Immunology. PMID 29080785 DOI: 10.1016/J.Dci.2017.10.016 |
0.482 |
|
| 2016 |
Haery L, Mussakhan S, Waxman DJ, Gilmore TD. Evidence for an oncogenic modifier role for mutant histone acetyltransferases in diffuse large B-cell lymphoma. Leukemia & Lymphoma. 1-11. PMID 27003102 DOI: 10.3109/10428194.2016.1160083 |
0.475 |
|
| 2015 |
Haery L, Thompson RC, Gilmore TD. Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy. Genes & Cancer. 6: 184-213. PMID 26124919 DOI: 10.18632/Genesandcancer.65 |
0.59 |
|
| 2015 |
Yeo AT, Chennamadhavuni S, Whitty A, Porco JA, Gilmore TD. Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines. Molecules (Basel, Switzerland). 20: 7474-94. PMID 25915462 DOI: 10.3390/Molecules20057474 |
0.54 |
|
| 2015 |
Finnerty JR, Gilmore TD. Methods for analyzing the evolutionary relationship of NF-κB proteins using free, web-driven bioinformatics and phylogenetic tools. Methods in Molecular Biology (Clifton, N.J.). 1280: 631-46. PMID 25736776 DOI: 10.1007/978-1-4939-2422-6_37 |
0.451 |
|
| 2015 |
Siggers T, Gilmore TD, Barron B, Penvose A. Characterizing the DNA binding site specificity of NF-κB with protein-binding microarrays (PBMs). Methods in Molecular Biology (Clifton, N.J.). 1280: 609-30. PMID 25736775 DOI: 10.1007/978-1-4939-2422-6_36 |
0.464 |
|
| 2015 |
Gilmore TD, Gélinas C. Methods for assessing the in vitro transforming activity of NF-κB transcription factor c-Rel and related proteins. Methods in Molecular Biology (Clifton, N.J.). 1280: 427-46. PMID 25736765 DOI: 10.1007/978-1-4939-2422-6_26 |
0.482 |
|
| 2015 |
Alshanbayeva A, Thomas A, Tremblay M, Abbas M, Abdurrob F, Almojel T, Aparicio A, Asarpota D, Ayers A, Aziz A, Bishop J, Christie T, Chua MJM, Chung O, Dhar N, ... ... Gilmore TD, et al. N- and C-terminal non-conserved residues contribute to transactivation by a sea anemone (Nematostella vectensis) NF-κB transcription factor Bios. 86: 165-175. DOI: 10.1893/0005-3155-86.4.165 |
0.496 |
|
| 2014 |
Zhou L, Yeo AT, Ballarano C, Weber U, Allen KN, Gilmore TD, Whitty A. Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO). Biochemistry. 53: 7929-44. PMID 25400026 DOI: 10.1021/Bi500920N |
0.423 |
|
| 2014 |
Haery L, Lugo-Picó JG, Henry RA, Andrews AJ, Gilmore TD. Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth. Molecular Cancer. 13: 29. PMID 24529102 DOI: 10.1186/1476-4598-13-29 |
0.416 |
|
| 2013 |
Cote SM, Gilmore TD, Shaffer R, Weber U, Bollam R, Golden MS, Glover K, Herscovitch M, Ennis T, Allen KN, Whitty A. Mutation of nonessential cysteines shows that the NF-κB essential modulator forms a constitutive noncovalent dimer that binds IκB kinase-β with high affinity. Biochemistry. 52: 9141-54. PMID 24266532 DOI: 10.1021/Bi401368R |
0.81 |
|
| 2013 |
Thompson RC, Vardinogiannis I, Gilmore TD. Identification of an NF-κB p50/p65-responsive site in the human MIR155HG promoter. Bmc Molecular Biology. 14: 24. PMID 24059932 DOI: 10.1186/1471-2199-14-24 |
0.653 |
|
| 2013 |
Thompson RC, Vardinogiannis I, Gilmore TD. The sensitivity of diffuse large B-cell lymphoma cell lines to histone deacetylase inhibitor-induced apoptosis is modulated by BCL-2 family protein activity. Plos One. 8: e62822. PMID 23667527 DOI: 10.1371/Journal.Pone.0062822 |
0.591 |
|
| 2013 |
Layden MJ, Röttinger E, Wolenski FS, Gilmore TD, Martindale MQ. Microinjection of mRNA or morpholinos for reverse genetic analysis in the starlet sea anemone, Nematostella vectensis. Nature Protocols. 8: 924-34. PMID 23579781 DOI: 10.1038/Nprot.2013.009 |
0.729 |
|
| 2013 |
Wolenski FS, Layden MJ, Martindale MQ, Gilmore TD, Finnerty JR. Characterizing the spatiotemporal expression of RNAs and proteins in the starlet sea anemone, Nematostella vectensis. Nature Protocols. 8: 900-15. PMID 23579779 DOI: 10.1038/Nprot.2013.014 |
0.749 |
|
| 2013 |
Stefanik DJ, Wolenski FS, Friedman LE, Gilmore TD, Finnerty JR. Isolation of DNA, RNA and protein from the starlet sea anemone Nematostella vectensis. Nature Protocols. 8: 892-9. PMID 23579778 DOI: 10.1038/Nprot.2012.151 |
0.733 |
|
| 2013 |
Wolenski FS, Bradham CA, Finnerty JR, Gilmore TD. NF-κB is required for cnidocyte development in the sea anemone Nematostella vectensis. Developmental Biology. 373: 205-15. PMID 23063796 DOI: 10.1016/J.Ydbio.2012.10.004 |
0.818 |
|
| 2012 |
Gilmore TD, Wolenski FS. NF-κB: where did it come from and why? Immunological Reviews. 246: 14-35. PMID 22435545 DOI: 10.1111/J.1600-065X.2012.01096.X |
0.813 |
|
| 2012 |
Yeo AT, Porco JA, Gilmore TD. Bcl-XL, but not Bcl-2, can protect human B-lymphoma cell lines from parthenolide-induced apoptosis. Cancer Letters. 318: 53-60. PMID 22155272 DOI: 10.1016/J.Canlet.2011.11.035 |
0.442 |
|
| 2012 |
Gilmore T, Wolenski F, Finnerty J. Preparation of antiserum and detection of proteins by Western blotting using the starlet sea anemone, Nematostella vectensis Protocol Exchange. DOI: 10.1038/Protex.2012.057 |
0.73 |
|
| 2012 |
Garbati MR, Thompson RC, Haery L, Gilmore TD. Erratum to “A rearranged EP300 gene in the human B-cell lymphoma cell line RC-K8 encodes a disabled transcriptional co-activator that contributes to cell growth and oncogenicity” [Cancer Lett 302 (2011) 76–83] Cancer Letters. 315: 96. DOI: 10.1016/J.Canlet.2011.09.017 |
0.809 |
|
| 2011 |
Gilmore TD, Gerondakis S. The c-Rel Transcription Factor in Development and Disease. Genes & Cancer. 2: 695-711. PMID 22207895 DOI: 10.1177/1947601911421925 |
0.485 |
|
| 2011 |
Wolenski FS, Chandani S, Stefanik DJ, Jiang N, Chu E, Finnerty JR, Gilmore TD. Two polymorphic residues account for the differences in DNA binding and transcriptional activation by NF-κB proteins encoded by naturally occurring alleles in Nematostella vectensis. Journal of Molecular Evolution. 73: 325-36. PMID 22198650 DOI: 10.1007/S00239-011-9479-7 |
0.818 |
|
| 2011 |
Garbati MR, Thompson RC, Haery L, Gilmore TD. A rearranged EP300 gene in the human B-cell lymphoma cell line RC-K8 encodes a disabled transcriptional co-activator that contributes to cell growth and oncogenicity. Cancer Letters. 302: 76-83. PMID 21232847 DOI: 10.1016/J.Canlet.2010.12.018 |
0.808 |
|
| 2011 |
Wolenski FS, Garbati MR, Lubinski TJ, Traylor-Knowles N, Dresselhaus E, Stefanik DJ, Goucher H, Finnerty JR, Gilmore TD. Characterization of the core elements of the NF-κB signaling pathway of the sea anemone Nematostella vectensis. Molecular and Cellular Biology. 31: 1076-87. PMID 21189285 DOI: 10.1128/Mcb.00927-10 |
0.822 |
|
| 2011 |
Gilmore TD, Garbati MR. Inhibition of NF-κB signaling as a strategy in disease therapy. Current Topics in Microbiology and Immunology. 349: 245-63. PMID 21113699 DOI: 10.1007/82_2010_105 |
0.818 |
|
| 2011 |
Thompson RC, Herscovitch M, Zhao I, Ford TJ, Gilmore TD. NF-κB down-regulates expression of the B-lymphoma marker CD10 through a miR-155/PU.1 pathway Journal of Biological Chemistry. 286: 1675-1682. PMID 20947507 DOI: 10.1074/Jbc.M110.177063 |
0.799 |
|
| 2010 |
Gilmore TD, Thompson RC, Faber AC. Cyclins D3 and E go hand in hand with Cdk4/6 in diffuse large B-cell lymphoma. Cell Cycle (Georgetown, Tex.). 9: 448-9. PMID 20130454 DOI: 10.4161/Cc.9.3.11009 |
0.535 |
|
| 2010 |
Garbati MR, Alço G, Gilmore TD. Histone acetyltransferase p300 is a coactivator for transcription factor REL and is C-terminally truncated in the human diffuse large B-cell lymphoma cell line RC-K8. Cancer Letters. 291: 237-45. PMID 19948376 DOI: 10.1016/J.Canlet.2009.10.018 |
0.814 |
|
| 2009 |
Sullivan JC, Wolenski FS, Reitzel AM, French CE, Traylor-Knowles N, Gilmore TD, Finnerty JR. Two alleles of NF-kappaB in the sea anemone Nematostella vectensis are widely dispersed in nature and encode proteins with distinct activities. Plos One. 4: e7311. PMID 19806194 DOI: 10.1371/Journal.Pone.0007311 |
0.804 |
|
| 2009 |
Chin M, Herscovitch M, Zhang N, Waxman DJ, Gilmore TD. Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile. Oncogene. 28: 2100-11. PMID 19377508 DOI: 10.1038/Onc.2009.74 |
0.829 |
|
| 2009 |
Gilmore TD, Perkins ND, Franzoso G. Getting away from it all in Capri: The 2008 EMBO workshop on NF-κB Cell Death and Differentiation. 16: 651-654. PMID 19287453 DOI: 10.1038/Cdd.2009.3 |
0.391 |
|
| 2008 |
Garbati MR, Gilmore TD. Ser484 and Ser494 in REL are the major sites of IKK phosphorylation in vitro: evidence that IKK does not directly enhance GAL4-REL transactivation. Gene Expression. 14: 195-205. PMID 19110719 DOI: 10.3727/105221608786883807 |
0.812 |
|
| 2008 |
Leeman JR, Gilmore TD. Alternative splicing in the NF-kappaB signaling pathway. Gene. 423: 97-107. PMID 18718859 DOI: 10.1016/J.Gene.2008.07.015 |
0.801 |
|
| 2008 |
Leeman JR, Weniger MA, Barth TF, Gilmore TD. Deletion analysis and alternative splicing define a transactivation inhibitory domain in human oncoprotein REL. Oncogene. 27: 6770-81. PMID 18695674 DOI: 10.1038/Onc.2008.284 |
0.779 |
|
| 2008 |
Herscovitch M, Comb W, Ennis T, Coleman K, Yong S, Armstead B, Kalaitzidis D, Chandani S, Gilmore TD. Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347. Biochemical and Biophysical Research Communications. 367: 103-8. PMID 18164680 DOI: 10.1016/J.Bbrc.2007.12.123 |
0.792 |
|
| 2007 |
Gilmore TD. Multiple myeloma: lusting for NF-kappaB. Cancer Cell. 12: 95-7. PMID 17692798 DOI: 10.1016/J.Ccr.2007.07.010 |
0.5 |
|
| 2007 |
Sullivan JC, Kalaitzidis D, Gilmore TD, Finnerty JR. Rel homology domain-containing transcription factors in the cnidarian Nematostella vectensis. Development Genes and Evolution. 217: 63-72. PMID 17120026 DOI: 10.1007/S00427-006-0111-6 |
0.785 |
|
| 2007 |
Starczynowski DT, Trautmann H, Pott C, Harder L, Arnold N, Africa JA, Leeman JR, Siebert R, Gilmore TD. Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity. Oncogene. 26: 2685-94. PMID 17072339 DOI: 10.1038/Sj.Onc.1210089 |
0.826 |
|
| 2006 |
Gilmore TD, Herscovitch M. Inhibitors of NF-κB signaling: 785 and counting Oncogene. 25: 6887-6899. PMID 17072334 DOI: 10.1038/Sj.Onc.1209982 |
0.823 |
|
| 2006 |
Courtois G, Gilmore TD. Mutations in the NF-κB signaling pathway: Implications for human disease Oncogene. 25: 6831-6843. PMID 17072331 DOI: 10.1038/Sj.Onc.1209939 |
0.467 |
|
| 2006 |
Gilmore TD. Introduction to NF-κB: Players, pathways, perspectives Oncogene. 25: 6680-6684. PMID 17072321 DOI: 10.1038/Sj.Onc.1209954 |
0.486 |
|
| 2006 |
Perkins ND, Gilmore TD. Good cop, bad cop: The different faces of NF-κB Cell Death and Differentiation. 13: 759-772. PMID 16410803 DOI: 10.1038/Sj.Cdd.4401838 |
0.507 |
|
| 2006 |
Liang MC, Bardhan S, Pace EA, Rosman D, Beutler JA, Porco JA, Gilmore TD. Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity. Biochemical Pharmacology. 71: 634-45. PMID 16360644 DOI: 10.1016/J.Bcp.2005.11.013 |
0.835 |
|
| 2006 |
Liang MC, Bardhan S, Porco JA, Gilmore TD. The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IkappaBalpha-deficient diffuse large B-cell lymphoma cell line. Cancer Letters. 241: 69-78. PMID 16289774 DOI: 10.1016/J.Canlet.2005.10.004 |
0.683 |
|
| 2005 |
Gapuzan ME, Schmah O, Pollock AD, Hoffmann A, Gilmore TD. Immortalized fibroblasts from NF-kappaB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor alpha after transformation by v-Ras. Oncogene. 24: 6574-83. PMID 16027734 DOI: 10.1038/Sj.Onc.1208809 |
0.404 |
|
| 2005 |
Starczynowski DT, Reynolds JG, Gilmore TD. Mutations of tumor necrosis factor alpha-responsive serine residues within the C-terminal transactivation domain of human transcription factor REL enhance its in vitro transforming ability. Oncogene. 24: 7355-68. PMID 16027730 DOI: 10.1038/Sj.Onc.1208902 |
0.661 |
|
| 2005 |
Kalaitzidis D, Gilmore TD. Transcription factor cross-talk: the estrogen receptor and NF-kappaB. Trends in Endocrinology and Metabolism: Tem. 16: 46-52. PMID 15734144 DOI: 10.1016/J.Tem.2005.01.004 |
0.75 |
|
| 2005 |
Trautmann H, Starczynowski DT, Pott C, Harder L, Arnold N, Siebert R, Kneba M, Gilmore TD. An Activating Mutation (Ser525Pro) within the Transactivation Domain of REL in Two Patients with Human B-Cell Lymphomas Enhances REL’s In Vitro Transforming Activity. Blood. 106: 2617-2617. DOI: 10.1182/Blood.V106.11.2617.2617 |
0.693 |
|
| 2004 |
Kalaitzidis D, Ok J, Sulak L, Starczynowski DT, Gilmore TD. Characterization of a human REL-estrogen receptor fusion protein with a reverse conditional transforming activity in chicken spleen cells. Oncogene. 23: 7580-7. PMID 15326488 DOI: 10.1038/Sj.Onc.1207912 |
0.797 |
|
| 2004 |
Gilmore TD, Starczynowski DT, Kalaitzidis D. RELevant gene amplification in B-cell lymphomas? Blood. 103: 3243-4; author reply. PMID 15070712 DOI: 10.1182/Blood-2003-11-4019 |
0.83 |
|
| 2004 |
Gilmore TD, Kalaitzidis D, Liang MC, Starczynowski DT. The c-Rel transcription factor and B-cell proliferation: a deal with the devil. Oncogene. 23: 2275-86. PMID 14755244 DOI: 10.1038/Sj.Onc.1207410 |
0.827 |
|
| 2003 |
Gilmore TD, Jean-Jacques J, Richards R, Cormier C, Kim J, Kalaitzidis D. Stable expression of the avian retroviral oncoprotein v-Rel in avian, mouse, and dog cell lines. Virology. 316: 9-16. PMID 14599786 DOI: 10.1016/S0042-6822(03)00562-2 |
0.72 |
|
| 2003 |
Starczynowski DT, Reynolds JG, Gilmore TD. Deletion of either C-terminal transactivation subdomain enhances the in vitro transforming activity of human transcription factor REL in chicken spleen cells. Oncogene. 22: 6928-36. PMID 14534540 DOI: 10.1038/Sj.Onc.1206801 |
0.671 |
|
| 2003 |
Gapuzan ME, Pitoc GA, Gilmore TD. Mutations within a conserved protein kinase A recognition sequence confer temperature-sensitive and partially defective activities onto mouse c-Rel. Biochemical and Biophysical Research Communications. 307: 92-9. PMID 12849986 DOI: 10.1016/S0006-291X(03)01123-9 |
0.372 |
|
| 2003 |
Liang MC, Bardhan S, Li C, Pace EA, Porco JA, Gilmore TD. Jesterone dimer, a synthetic derivative of the fungal metabolite jesterone, blocks activation of transcription factor nuclear factor kappaB by inhibiting the inhibitor of kappaB kinase. Molecular Pharmacology. 64: 123-31. PMID 12815168 DOI: 10.1124/Mol.64.1.123 |
0.835 |
|
| 2003 |
Gilmore TD. The Re1/NF-kappa B/I kappa B signal transduction pathway and cancer. Cancer Treatment and Research. 115: 241-65. PMID 12613200 |
0.314 |
|
| 2003 |
Wang Y, Gilmore TD. Zyxin and paxillin proteins: focal adhesion plaque LIM domain proteins go nuclear. Biochimica Et Biophysica Acta. 1593: 115-20. PMID 12581855 DOI: 10.1016/S0167-4889(02)00349-X |
0.369 |
|
| 2002 |
Kalaitzidis D, Davis RE, Rosenwald A, Staudt LM, Gilmore TD. The human B-cell lymphoma cell line RC-K8 has multiple genetic alterations that dysregulate the Rel/NF-kappaB signal transduction pathway. Oncogene. 21: 8759-68. PMID 12483529 DOI: 10.1038/Sj.Onc.1206033 |
0.766 |
|
| 2002 |
Gilmore T, Gapuzan ME, Kalaitzidis D, Starczynowski D. Rel/NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer. Cancer Letters. 181: 1-9. PMID 12430173 DOI: 10.1016/S0304-3835(01)00795-9 |
0.832 |
|
| 2002 |
Li C, Bardhan S, Pace EA, Liang MC, Gilmore TD, Porco JA. Angiogenesis inhibitor epoxyquinol a: total synthesis and inhibition of transcription factor NF-kappaB. Organic Letters. 4: 3267-70. PMID 12227765 DOI: 10.1021/Ol026513N |
0.807 |
|
| 2002 |
Gapuzan ME, Yufit PV, Gilmore TD. Immortalized embryonic mouse fibroblasts lacking the RelA subunit of transcription factor NF-kappaB have a malignantly transformed phenotype. Oncogene. 21: 2484-92. PMID 11971183 DOI: 10.1038/Sj.Onc.1205333 |
0.467 |
|
| 2002 |
Kalaitzidis D, Gilmore TD. Genomic organization and expression of the rearranged REL proto-oncogene in the human B-cell lymphoma cell line RC-K8. Genes, Chromosomes & Cancer. 34: 129-35. PMID 11921291 DOI: 10.1002/Gcc.10051 |
0.746 |
|
| 2002 |
Li C, Bardhan S, Pace EA, Liang MC, Gilmore TD, Porco JA. Angiogenesis inhibitor epoxyquinol A: Total synthesis and inhibition of transcription factor NF-κB Organic Letters. 4: 3267-3270. DOI: 10.1021/ol026513n |
0.797 |
|
| 2001 |
Gilmore TD, Cormier C, Jean-Jacques J, Gapuzan ME. Malignant transformation of primary chicken spleen cells by human transcription factor c-Rel. Oncogene. 20: 7098-103. PMID 11704834 DOI: 10.1038/Sj.Onc.1204898 |
0.494 |
|
| 2001 |
Li C, Pace EA, Liang MC, Lobkovsky E, Gilmore TD, Porco JA. Total synthesis of the NF-kappa B inhibitor (-)-cycloepoxydon: utilization of tartrate-mediated nucleophilic epoxidation. Journal of the American Chemical Society. 123: 11308-9. PMID 11697981 DOI: 10.1021/Ja0169769 |
0.808 |
|
| 2001 |
Piffat KA, Hrdlicková R, Nehyba J, Ikeda T, Liss A, Huang S, Sif S, Gilmore TD, Bose HR. The chicken RelB transcription factor has transactivation sequences and a tissue-specific expression pattern that are distinct from mammalian RelB. Molecular Cell Biology Research Communications : McBrc. 4: 266-75. PMID 11529676 DOI: 10.1006/Mcbr.2001.0290 |
0.796 |
|
| 2001 |
Wang Y, Gilmore TD. LIM domain protein Trip6 has a conserved nuclear export signal, nuclear targeting sequences, and multiple transactivation domains Biochimica Et Biophysica Acta - Molecular Cell Research. 1538: 260-272. PMID 11336797 DOI: 10.1016/S0167-4889(01)00077-5 |
0.413 |
|
| 2001 |
Barkett M, Dooher JE, Lemonnier L, Simmons L, Scarpati JN, Wang Y, Gilmore TD. Three mutations in v-Rel render it resistant to cleavage by cell-death protease caspase-3. Biochimica Et Biophysica Acta. 1526: 25-36. PMID 11287119 DOI: 10.1016/S0304-4165(01)00092-7 |
0.801 |
|
| 2000 |
Epinat JC, Dvorin EL, Gilmore TD. Envelope-dependent transactivation by the retroviral oncoprotein v-Rel is required for efficient malignant transformation of chicken spleen cells Oncogene. 19: 3131-3137. PMID 10918567 DOI: 10.1038/Sj.Onc.1203651 |
0.347 |
|
| 2000 |
Epinat JC, Kazandjian D, Harkness DD, Petros S, Dave J, White DW, Gilmore TD. Mutant envelope residues confer a transactivation function onto N-terminal sequences of the v-Rel oncoprotein. Oncogene. 19: 599-607. PMID 10698504 DOI: 10.1038/Sj.Onc.1203376 |
0.423 |
|
| 1999 |
Zhao MK, Wang Y, Murphy K, Yi J, Beckerle MC, Gilmore TD. LIM domain-containing protein trip6 can act as a coactivator for the v-Rel transcription factor. Gene Expression. 8: 207-17. PMID 10794523 |
0.373 |
|
| 1999 |
Gilmore TD. Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel Oncogene. 18: 6925-6937. PMID 10602467 DOI: 10.1038/Sj.Onc.1203222 |
0.477 |
|
| 1999 |
Barkett M, Gilmore TD. Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene. 18: 6910-24. PMID 10602466 DOI: 10.1038/Sj.Onc.1203238 |
0.818 |
|
| 1999 |
Epinat JC, Gilmore TD. Diverse agents act at multiple levels to inhibit the Rel/NF-κB signal transduction pathway Oncogene. 18: 6896-6909. PMID 10602465 DOI: 10.1038/Sj.Onc.1203218 |
0.472 |
|
| 1999 |
Epinat JC, Gilmore TD. In vitro-translated diphtheria toxin A chain inhibits translation in wheat germ extracts: Analysis of biologically active, caspase-3-resistant diphtheria toxin mutants Biochimica Et Biophysica Acta - General Subjects. 1472: 34-41. PMID 10572923 DOI: 10.1016/S0304-4165(99)00101-4 |
0.37 |
|
| 1999 |
Wang Y, Dooher JE, Koedood Zhao M, Gilmore TD. Characterization of mouse Trip6: A putative intracellular signaling protein Gene. 234: 403-409. PMID 10395914 DOI: 10.1016/S0378-1119(99)00168-7 |
0.378 |
|
| 1999 |
Gilmore TD. The Rel/NF-κB signal transduction pathway: Introduction Oncogene. 18: 6842-6844. DOI: 10.1038/Sj.Onc.1203237 |
0.402 |
|
| 1998 |
Sylla BS, Hung SC, Davidson DM, Hatzivassiliou E, Malinin NL, Wallach D, Gilmore TD, Kieff E, Mosialos G. Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta. Proceedings of the National Academy of Sciences of the United States of America. 95: 10106-11. PMID 9707608 DOI: 10.1073/Pnas.95.17.10106 |
0.484 |
|
| 1997 |
Barkett M, Xue D, Horvitz HR, Gilmore TD. Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro. The Journal of Biological Chemistry. 272: 29419-22. PMID 9367996 DOI: 10.1074/Jbc.272.47.29419 |
0.788 |
|
| 1997 |
White DW, Gilmore TD. Transcription factors, oncogenes, and apoptosis. Science (New York, N.Y.). 276: 185. PMID 9132938 DOI: 10.1126/Science.276.5310.181F |
0.36 |
|
| 1997 |
Gilmore TD. Introduction: The Rel/NF-κB signal transduction pathway Seminars in Cancer Biology. 8: 61-62. DOI: 10.1006/Scbi.1997.0056 |
0.402 |
|
| 1996 |
Gilmore TD, Koedood M, Piffat KA, White DW. Rel/NF-kappaB/IkappaB proteins and cancer. Oncogene. 13: 1367-78. PMID 8875974 |
0.8 |
|
| 1996 |
White DW, Gilmore TD. Bcl-2 and CrmA have different effects on transformation, apoptosis and the stability of I kappa B-alpha in chicken spleen cells transformed by temperature-sensitive v-Rel oncoproteins. Oncogene. 13: 891-9. PMID 8806678 |
0.322 |
|
| 1996 |
White DW, Pitoc GA, Gilmore TD. Interaction of the v-Rel oncoprotein with NF-kappaB and IkappaB proteins: heterodimers of a transformation-defective v-Rel mutant and NF-2 are functional in vitro and in vivo. Molecular and Cellular Biology. 16: 1169-78. PMID 8622661 DOI: 10.1128/Mcb.16.3.1169 |
0.457 |
|
| 1996 |
Gilmore TD, Koedood M, Piffat KA, White DW. Rel/NF-κB/IκB proteins and cancer Oncogene. 13: 1367-1378. |
0.8 |
|
| 1994 |
Feinstein R, Bolton WK, Quinones JN, Mosialos G, Sif S, Huff JL, Capobianco AJ, Gilmore TD. Characterization of a chicken cDNA encoding the retinoblastoma gene product Bba - Gene Structure and Expression. 1218: 82-86. PMID 8193168 DOI: 10.1016/0167-4781(94)90103-1 |
0.343 |
|
| 1994 |
Sif S, Gilmore TD. Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1 Journal of Virology. 68: 7131-7138. PMID 7933095 DOI: 10.1128/Jvi.68.11.7131-7138.1994 |
0.354 |
|
| 1993 |
Morin PJ, Subramanian GS, Gilmore TD. GAL4-lκ{script}bα and GAL4-lκ{script}bγ activate transcription by different mechanisms Nucleic Acids Research. 21: 2157-2163. PMID 8502557 DOI: 10.1093/Nar/21.9.2157 |
0.456 |
|
| 1993 |
Capobianco AJ, Gilmore TD. A Conditional Mutant of vRel Containing Sequences from the Human Estrogen Receptor Virology. 193: 160-170. PMID 8438564 DOI: 10.1006/Viro.1993.1112 |
0.364 |
|
| 1993 |
Sif S, Gilmore TD. NF-κB p100 is one of the high-molecular-weight proteins complexed with the v-Rel oncoprotein in transformed chicken spleen cells Journal of Virology. 67: 7612-7617. PMID 8230480 |
0.337 |
|
| 1993 |
Gilmore TD, Morin PJ. The IκB proteins: members of a multifunctional family Trends in Genetics. 9: 427-433. PMID 8122310 DOI: 10.1016/0168-9525(93)90106-R |
0.487 |
|
| 1992 |
Morin PJ, Gilmore TD. The c terminus of the nf-χb p50 precursor and an iχb isoform contain transcription activation domains Nucleic Acids Research. 20: 2453-2458. PMID 1598203 DOI: 10.1093/Nar/20.10.2453 |
0.429 |
|
| 1992 |
Capobianco AJ, Chang D, Mosialos G, Gilmore TD. p105, the NF-κB p50 precursor protein, is one of the cellular proteins complexed with the v-Rel oncoprotein in transformed chicken spleen cells Journal of Virology. 66: 3758-3767. PMID 1533881 DOI: 10.1128/Jvi.66.6.3758-3767.1992 |
0.382 |
|
| 1992 |
Gilmore TD. Role of rel family genes in normal and malignant lymphoid cell growth Cancer Surveys. 15: 69-88. PMID 1451115 |
0.333 |
|
| 1991 |
Mosialos G, Hamer P, Capobianco AJ, Laursen RA, Gilmore TD. A protein kinase-A recognition sequence is structurally linked to transformation by p59v-rel and cytoplasmic retention of p68c-rel. Molecular and Cellular Biology. 11: 5867-77. PMID 1944267 DOI: 10.1128/Mcb.11.12.5867 |
0.44 |
|
| 1991 |
Richardson PM, Gilmore TD. vRel is an inactive member of the rel family of transcriptional activating proteins Journal of Virology. 65: 3122-3130. PMID 1903456 DOI: 10.1128/Jvi.65.6.3122-3130.1991 |
0.444 |
|
| 1991 |
Gilmore TD. Malignant transformation by mutant Rel proteins Trends in Genetics. 7: 318-322. PMID 1781029 DOI: 10.1016/0168-9525(91)90421-L |
0.339 |
|
| 1991 |
Capobianco AJ, Gilmore TD. Repression of the chicken c-rel promoter by vRel in chicken embryo fibroblasts is not mediated through a consensus NF-κB binding site Oncogene. 6: 2203-2210. PMID 1766669 |
0.315 |
|
| 1990 |
Gilmore TD. NF-κB, KBF1, dorsal, and related matters Cell. 62: 841-843. PMID 2203533 DOI: 10.1016/0092-8674(90)90257-F |
0.406 |
|
| 1990 |
Kamens J, Richardson P, Mosialos G, Brent R, Gilmore T. Oncogenic transformation by vrel requires an amino-terminal activation domain. Molecular and Cellular Biology. 10: 2840-2847. PMID 2111443 DOI: 10.1128/Mcb.10.6.2840 |
0.366 |
|
| 1988 |
Gilmore TD, Temin HM. v-rel Oncoproteins in the nucleus and in the cytoplasm transform chicken spleen cells Journal of Virology. 62: 703-714. PMID 2828665 DOI: 10.1128/Jvi.62.3.703-714.1988 |
0.365 |
|
| 1987 |
Luk KC, Gilmore TD, Panganivan AT. The spleen necrosis virus int gene product expressed in Escherichia coli has DNA binding activity and mediates att and U5-specific DNA multimer formation in Vitro Virology. 157: 127-136. PMID 3548033 DOI: 10.1016/0042-6822(87)90321-7 |
0.309 |
|
| 1985 |
Gilmore T, Declue JE, Martin GS. Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro Cell. 40: 609-618. PMID 2982500 DOI: 10.1016/0092-8674(85)90209-0 |
0.342 |
|
| 1982 |
Gilmore TD, Radke K, Martin GS. Tyrosine phosphorylation of a 50K cellular polypeptide associated with the Rous sarcoma virus transforming protein pp60(src) Molecular and Cellular Biology. 2: 199-206. PMID 6287229 DOI: 10.1128/Mcb.2.2.199 |
0.3 |
|
| 1980 |
Pawson T, Guyden J, Kung TH, Radke K, Gilmore T, Steven Martin G. A strain of Fujinami sarcoma virus which is temperature-sensitive in protein phosphorylation and cellular transformation Cell. 22: 767-775. PMID 6257397 DOI: 10.1016/0092-8674(80)90553-X |
0.319 |
|
| 1980 |
Radke K, Gilmore T, Martin GS. Transformation by Rous sarcoma virus: A cellular substrate for transformation-specific protein phosphorylation contains phosphotyrosine Cell. 21: 821-828. PMID 6159984 DOI: 10.1016/0092-8674(80)90445-6 |
0.309 |
|
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