Lee A. Denson - Publications

Affiliations: 
Cell & Molecular Biology University of Cincinnati, Cincinnati, OH 
Area:
Cell Biology, Immunology, Genetics

226 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Braun T, Sosnovski KE, Amir A, BenShoshan M, VanDussen KL, Karns R, Levhar N, Abbas-Egbariya H, Hadar R, Efroni G, Castel D, Avivi C, Rosen MJ, Grifiths AM, Walters TD, ... ... Denson LA, et al. Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn disease, and celiac disease. Jci Insight. PMID 37261910 DOI: 10.1172/jci.insight.170181  0.309
2023 Wu Y, Gettler K, Kars ME, Giri M, Li D, Bayrak CS, Zhang P, Jain A, Maffucci P, Sabic K, Van Vleck T, Nadkarni G, Denson LA, Ostrer H, Levine AP, et al. Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature Communications. 14: 2256. PMID 37080976 DOI: 10.1038/s41467-023-37849-3  0.308
2022 Jurickova I, Bonkowski E, Angerman E, Novak E, Huron A, Akers G, Iwasawa K, Braun T, Hadar R, Hooker M, Han S, Cutler DJ, Okou DT, Kugathasan S, Jegga A, ... ... Denson LA, et al. Eicosatetraynoic Acid and Butyrate Regulate Human Intestinal Organoid Mitochondrial and Extracellular Matrix Pathways Implicated in Crohn's Disease Strictures. Inflammatory Bowel Diseases. PMID 35259271 DOI: 10.1093/ibd/izac037  0.68
2022 Abbas-Egbariya H, Haberman Y, Braun T, Hadar R, Denson L, Gal-Mor O, Amir A. Meta-analysis defines predominant shared microbial responses in various diseases and a specific inflammatory bowel disease signal. Genome Biology. 23: 61. PMID 35197084 DOI: 10.1186/s13059-022-02637-7  0.359
2022 Venkateswaran S, Somineni HK, Kilaru V, Katrinli S, Prince J, Okou DT, Hyams JS, Denson LA, Kellermayer R, Gibson G, Cutler DJ, Smith AK, Kugathasan S, Conneely KN. Methylation Quantitative Trait Loci are Largely Consistent across Disease States in Crohn's disease. G3 (Bethesda, Md.). PMID 35172000 DOI: 10.1093/g3journal/jkac041  0.707
2022 Shoda T, Collins MH, Rochman M, Wen T, Caldwell JM, Mack LE, Osswald GA, Besse JA, Haberman Y, Aceves SS, Arva NC, Capocelli KE, Chehade M, Davis CM, Dellon ES, ... ... Denson LA, et al. Evaluating Eosinophilic Colitis as a Unique Disease using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology. PMID 35085569 DOI: 10.1053/j.gastro.2022.01.022  0.349
2021 Somineni HK, Nagpal S, Venkateswaran S, Cutler DJ, Okou DT, Haritunians T, Simpson CL, Begum F, Datta LW, Quiros AJ, Seminerio J, Mengesha E, Alexander JS, Baldassano RN, Dudley-Brown S, ... ... Denson LA, et al. Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. American Journal of Human Genetics. PMID 33600772 DOI: 10.1016/j.ajhg.2021.02.001  0.712
2020 Potdar AA, Dube S, Naito T, Li K, Botwin G, Haritunians T, Li D, Casero D, Yang S, Bilsborough J, Perrigoue JG, Denson LA, Daly M, Targan SR, Fleshner P, et al. Altered intestinal ACE2 levels are associated with inflammation, severe disease and response to anti-cytokine therapy in IBD. Gastroenterology. PMID 33160965 DOI: 10.1053/j.gastro.2020.10.041  0.362
2020 Colman RJ, Tsai YT, Jackson K, Boyle BM, Noe JD, Hyams JS, D'Haens GRAM, van Limbergen J, Rosen MJ, Denson LA, Minar P. Achieving Target Infliximab Drug Concentrations Improves Blood and Fecal Neutrophil Biomarkers in Crohn's Disease. Inflammatory Bowel Diseases. PMID 32944769 DOI: 10.1093/Ibd/Izaa241  0.383
2020 Haberman Y, Minar P, Karns R, Dexheimer PJ, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Ta A, Walters TD, Baldassano RN, Noe JD, Rosh J, ... ... Denson LA, et al. Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease. Journal of Crohn's & Colitis. PMID 32770196 DOI: 10.1093/Ecco-Jcc/Jjaa166  0.376
2020 Mack DR, Saul B, Boyle B, Griffiths A, Sauer C, Markowitz J, LeLeiko N, Keljo D, Rosh JR, Baker SS, Steiner S, Heyman MB, Patel AS, Baldassano R, Noe J, ... ... Denson L, et al. Analysis of Using the Total White Blood Cell Count to Define Severe New Onset Ulcerative Colitis in Children. Journal of Pediatric Gastroenterology and Nutrition. PMID 32520830 DOI: 10.1097/Mpg.0000000000002797  0.301
2020 Potdar AA, Dube S, Naito T, Botwin G, Haritunians T, Li D, Yang S, Bilsborough J, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, et al. Reduced expression of COVID-19 host receptor, is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 32511625 DOI: 10.1101/2020.04.19.20070995  0.313
2020 Lyles JL, Mulgund AA, Bauman LE, Su W, Fei L, Chona DL, Sharma P, Etter RK, Hellmann J, Denson LA, Minar P, Dykes DM, Rosen MJ. Effect of a Practice-wide Anti-TNF Proactive Therapeutic Drug Monitoring Program on Outcomes in Pediatric Patients with Inflammatory Bowel Disease. Inflammatory Bowel Diseases. PMID 32448898 DOI: 10.1093/Ibd/Izaa102  0.358
2020 Haberman Ziv Y, Minar P, Karns R, Dexheimer P, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Aronow B, Gibson G, Hyams J, Kugathasan S, Jegga A, ... Denson L, et al. DOP89 Pre-treatment mucosal inflammatory and wound healing gene programmes reveal mechanisms associated with future stricturing behaviour during 5-year follow-up in paediatric Crohn’s disease Journal of Crohn's and Colitis. 14: S127-S127. DOI: 10.1093/Ecco-Jcc/Jjz203.128  0.348
2020 Haberman Ziv Y, Loberman-Nachum N, Katya S, Di Segni A, Efroni G, Braun T, BenShoshan M, Shouval D, Denson LA, Amir A, Unger R, Weiss B. OP06 Comparison between Crohn and coeliac diseases small intestine transcriptomics and microbial data define similarities and divergent pathways linked to pathogenesis Journal of Crohn's and Colitis. 14: S006-S006. DOI: 10.1093/Ecco-Jcc/Jjz203.005  0.474
2020 Sosnovski KE, BenShoshan M, Abbas-egbariya H, Saar EG, Efroni G, Braun T, Barshack I, Denson LA, Haberman Y. Tu1293 EPITHELIAL LONG NON-CODING RNA REGULATE IN-CIS NEIGHBORING TRANSCRIPTION FACTORS AND EPITHELIAL FUNCTIONS ASSOCIATED WITH CROHN DISEASE PATHOGENESIS Gastroenterology. 158: S-1046-S-1047. DOI: 10.1016/S0016-5085(20)33301-1  0.329
2020 Shih T, Yusung S, Li D, Gonsky R, Botwin GJ, Casero D, Ziring D, Rabizadeh S, Denson LA, Kugathasan S, McGovern DP, Braun JG. Su1988 ENVIRONMENTAL EFFECT OF RESOLVED HUMAN CMV INFECTION AND NK RECEPTOR GENETICS IN PEDIATRIC CROHN'S DISEASE SUSCEPTIBILITY AND PHENOTYPE. Gastroenterology. 158: S-735. DOI: 10.1016/S0016-5085(20)32514-2  0.343
2020 Schirmer M, Denson LA, Walters TD, Griffiths AM, Mack DR, Leleiko NS, Markowitz J, Boyle BM, Shah S, Rosh JR, Kugathasan S, Vlamakis H, Hyams JS, Xavier R. Su1219 GUT MICROBIAL STRAINS AND METABOLITES IN DISEASE COURSE OF PEDIATRIC ULCERATIVE COLITIS Gastroenterology. 158: S-548. DOI: 10.1016/S0016-5085(20)32067-9  0.362
2020 TA A, Ollberding N, Karns R, Haberman Y, Baldassano RN, Markowitz J, Heyman M, Kirschner BS, Oliva-Hemker M, Pfefferkorn MD, Kellermayer R, Snapper SB, Rabizadeh S, Hyams JS, Kugathasan S, ... ... Denson LA, et al. 1162 BASELINE ILEAL LUMINAL NARROWING IS ASSOCIATED WITH SPECIFIC PRE-TREATMENT MUCOSAL GENE PROGRAMS AND MICROBIAL SHIFTS AND SUBSEQUENT LIKELIHOOD OF TRANSMURAL HEALING IN PEDIATRIC CROHN'S DISEASE Gastroenterology. 158: S-234-S-235. DOI: 10.1016/S0016-5085(20)31272-5  0.379
2020 Haberman Y, Minar PP, Karns R, Dexheimer PJ, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Walters TD, Baldassano RN, Noe JD, Kellermayer R, Markowitz J, ... ... Denson LA, et al. 935 PRE-TREATMENT MUCOSAL INFLAMMATORY AND WOUND HEALING GENE PROGRAMS REVEAL MECHANISMS ASSOCIATED WITH FUTURE STRICTURING BEHAVIOR DURING FIVE YEAR FOLLOW-UP IN PEDIATRIC CROHN'S DISEASE Gastroenterology. 158: S-187-S-188. DOI: 10.1016/S0016-5085(20)31152-5  0.383
2020 Venkateswaran S, Somineni HK, Matthews J, Kilaru V, Denson LA, Hyams JS, Investigators P, Cutler DJ, Smith AK, Conneely KN, Kugathasan S. 614 RECTAL TISSUE DNA METHYLATION IN ULCERATIVE COLITIS SHOWS DISEASE-SPECIFIC ASSOCIATIONS: INSIGHTS FROM LONGITUDINAL ANALYSIS OF PROTECT STUDY PARTICIPANTS Gastroenterology. 158: S-131. DOI: 10.1016/S0016-5085(20)31007-6  0.322
2020 Khandelwal P, Lounder DT, Bartlett AL, Luebbering N, Lake KE, Litts B, Duell A, Karns R, Denson LA, Davies SM. Pediatric Acute Gvhd: Transcriptome Analysis of Gastrointestinal Biopsies Reveal a Unique Signature in Pediatric Acute GI Gvhd with Involvement of the ERK Pathway and Similarities with Pediatric Inflammatory Bowel Disease Biology of Blood and Marrow Transplantation. 26: S3-S6. DOI: 10.1016/J.Bbmt.2019.12.138  0.376
2019 Hellmann J, Andersen H, Fei L, Linn A, Bezold R, Lake K, Jackson K, Meyer D, Dirksing K, Bonkowski E, Ollberding NJ, Haslam DB, Denson L. Microbial Shifts and Shorter Time to Bowel Resection Surgery Associated with C. difficile in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. PMID 31725875 DOI: 10.1093/Ibd/Izz263  0.353
2019 Loberman-Nachum N, Sosnovski K, Di Segni A, Efroni G, Braun T, BenShoshan M, Anafi L, Avivi C, Barshack I, Shouval DS, Denson LA, Amir A, Unger R, Weiss B, Haberman Y. Defining the Celiac Disease Transcriptome using Clinical Pathology Specimens Reveals Biologic Pathways and Supports Diagnosis. Scientific Reports. 9: 16163. PMID 31700112 DOI: 10.1038/S41598-019-52733-1  0.433
2019 Martin JC, Chang C, Boschetti G, Ungaro R, Giri M, Grout JA, Gettler K, Chuang LS, Nayar S, Greenstein AJ, Dubinsky M, Walker L, Leader A, Fine JS, Whitehurst CE, ... ... Denson LA, et al. Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy. Cell. PMID 31474370 DOI: 10.1016/J.Cell.2019.08.008  0.353
2019 Naramore SK, Bennett WE, Jiang G, Kugathasan S, Denson LA, Hyams JS, Steiner SJ. Serologic, but not Genetic, Markers are Associated with Impaired Anthropometrics at Diagnosis of Pediatric Crohn's Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 31393333 DOI: 10.1097/Mpg.0000000000002462  0.429
2019 Carmody JK, Plevinsky J, Peugh JL, Denson LA, Hyams JS, Lobato D, LeLeiko NS, Hommel KA. Longitudinal non-adherence predicts treatment escalation in paediatric ulcerative colitis. Alimentary Pharmacology & Therapeutics. PMID 31373712 DOI: 10.1111/Apt.15445  0.302
2019 Vaz KKH, Carmody J, Zhang Y, Denson LA, Hommel KA. Evaluation of a Novel Educational Tool in Adolescents with Inflammatory Bowel Disease: The NEAT Study. Journal of Pediatric Gastroenterology and Nutrition. PMID 31261247 DOI: 10.1097/Mpg.0000000000002431  0.363
2019 Venkateswaran S, Denson LA, Jurickova I, Dodd A, Zwick ME, Cutler DJ, Kugathasan S, Okou DT. Neutrophil GM-CSF signaling in inflammatory bowel disease patients is influenced by non-coding genetic variants. Scientific Reports. 9: 9168. PMID 31235766 DOI: 10.1038/S41598-019-45701-2  0.714
2019 Clarkston K, Tsai YT, Jackson K, Rosen MJ, Denson LA, Minar P. Development of Infliximab Target Concentrations During Induction in Pediatric Crohn Disease Patients. Journal of Pediatric Gastroenterology and Nutrition. 69: 68-74. PMID 31232885 DOI: 10.1097/Mpg.0000000000002304  0.351
2019 Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, Andrews E, Ajami NJ, Bonham KS, Brislawn CJ, Casero D, Courtney H, Gonzalez A, Graeber TG, Hall AB, ... ... Denson LA, et al. Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. Nature. 569: 655-662. PMID 31142855 DOI: 10.1038/S41586-019-1237-9  0.46
2019 Denson LA, Curran M, McGovern DPB, Koltun WA, Duerr RH, Kim SC, Sartor RB, Sylvester FA, Abraham C, de Zoeten EF, Siegel CA, Burns RM, Dobes AM, Shtraizent N, Honig G, et al. Challenges in IBD Research: Precision Medicine. Inflammatory Bowel Diseases. 25: S31-S39. PMID 31095701 DOI: 10.1093/Ibd/Izz078  0.336
2019 Wu J, Lubman DM, Kugathasan S, Denson LA, Hyams JS, Dubinsky MC, Griffiths AM, Baldassano RN, Noe JD, Rabizadeh S, Gulati AS, Rosh JR, Crandall WV, Higgins PDR, Stidham RW. Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease. The American Journal of Gastroenterology. 114: 777-785. PMID 31058681 DOI: 10.14309/Ajg.0000000000000237  0.389
2019 Wright M, Chandrakasan S, Okou DT, Yin H, Jurickova I, Denson LA, Kugathasan S. Early Onset Granulomatous Colitis Associated with a Mutation in NCF4 Resolved with Hematopoietic Stem Cell Transplantation. The Journal of Pediatrics. PMID 31027832 DOI: 10.1016/J.Jpeds.2019.03.042  0.675
2019 Gray WN, Holbrook E, Dykes D, Morgan PJ, Saeed SA, Denson LA. improving IBD Transition, Self-management, and Disease Outcomes With an In-clinic Transition Coordinator. Journal of Pediatric Gastroenterology and Nutrition. PMID 30964817 DOI: 10.1097/Mpg.0000000000002350  0.312
2019 Hyams JS, Davis Thomas S, Gotman N, Haberman Y, Karns R, Schirmer M, Mo A, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, ... ... Denson LA, et al. Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study. Lancet (London, England). PMID 30935734 DOI: 10.1016/S0140-6736(18)32592-3  0.357
2019 Somineni HK, Venkateswaran S, Kilaru V, Marigorta UM, Mo A, Okou DT, Kellermayer R, Mondal K, Cobb D, Walters TD, Griffiths A, Noe JD, Crandall WV, Rosh JR, Mack DR, ... ... Denson LA, et al. Blood-derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation. Gastroenterology. PMID 30779925 DOI: 10.1053/J.Gastro.2019.01.270  0.73
2019 Gettler K, Giri M, Kenigsberg E, Martin J, Chuang LS, Hsu NY, Denson LA, Hyams JS, Griffiths A, Noe JD, Crandall WV, Mack DR, Kellermayer R, Abraham C, Hoffman G, et al. Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets. Genes and Immunity. PMID 30692607 DOI: 10.1038/S41435-019-0059-Y  0.367
2019 Haberman Y, Karns R, Dexheimer PJ, Schirmer M, Somekh J, Jurickova I, Braun T, Novak E, Bauman L, Collins MH, Mo A, Rosen MJ, Bonkowski E, Gotman N, Marquis A, ... ... Denson LA, et al. Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. Nature Communications. 10: 38. PMID 30604764 DOI: 10.1038/S41467-018-07841-3  0.39
2019 Krishnakumar C, Ballengee CR, Liu C, Kim MO, Baker SS, Baldassano RN, Cohen SA, Crandall WV, Denson LA, Dubinsky MC, Evans J, Gokhale R, Griffiths A, Guthery SL, Oliva-Hemker M, et al. Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study. Inflammatory Bowel Diseases. PMID 30601983 DOI: 10.1093/Ibd/Izy363  0.36
2019 Ahmed S, Iskandar H, Liu Z, Mondal K, Markowitz J, Hyams J, Denson L, Walters T, Dubinsky MC, Kugathasan S. Persisting Malnutrition After Medical Therapy in Children With Crohnʼs Disease Is Associated With Increased Rates of Surgery and Complicated Disease Behavior American Journal of Gastroenterology. 114: S459-S460. DOI: 10.14309/01.Ajg.0000592708.51441.3A  0.343
2019 Nagpal S, Mo A, Hyams JS, Marigorta U, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Baldassano RN, Rosh JR, Keljo DJ, Markowitz J, Walters TD, Kugathasan S, Denson LA, et al. Tu1760 – Alterations in Expression Quantitative Trait Loci from Diagnosis to Recovery in Pediatric Ulcerative Colitis Gastroenterology. 156: S-1113-S-1114. DOI: 10.1016/S0016-5085(19)39746-X  0.31
2019 Venkateswaran S, Somineni HK, Kilaru V, Hyams JS, Denson LA, Cutler DJ, Smith AK, Conneely KN, Kugathasan S. Tu1159 – Blood Mqtl Effects are Consistent During the Course of the Disease Regardless of Remission Or Relapse Status in Pediatric Crohn’s Disease Patients Gastroenterology. 156: S-967. DOI: 10.1016/S0016-5085(19)39373-4  0.394
2019 Fondell AW, Wang Z, Mack DR, Griffiths AM, Boyle BM, Patel AS, Sauer CG, Markowitz J, Rosh JR, Leleiko NS, Keljo DJ, Walters TD, Kugathasan S, Denson LA, Hyams JS. Su1790 – Infliximab Rescue Less Effective in Preventing Colectomy Early in the Course of Newly Diagnosed Ulcerative Colitis Gastroenterology. 156: S-612. DOI: 10.1016/S0016-5085(19)38427-6  0.305
2019 Hajjat T, Mosha MH, Bonkowski E, Denson LA, Hyams JS. 882 – Normalization of Fecal Calprotectin Requires Higher Trough Infliximab Levels in Children with Inflammatory Bowel Disease Gastroenterology. 156: S-200. DOI: 10.1016/S0016-5085(19)37292-0  0.395
2019 Whaley KG, Xiong Y, Karns R, Hyams JS, Kugathasan S, Boyle BM, Walters TD, Kelsen JR, Leleiko NS, Waddell A, Fox S, Haberman Y, Minar PP, Denson LA, Thomas S, et al. 235 – Early Infliximab Pharmacokinetics and Week One Clinical Response in Pediatric Acute Severe Ulcerative Colitis: the Arch Study Gastroenterology. 156: S-44. DOI: 10.1016/S0016-5085(19)36891-X  0.305
2018 Venkateswaran S, Marigorta UM, Denson LA, Hyams JS, Gibson G, Kugathasan S. Bowel Location Rather Than Disease Subtype Dominates Transcriptomic Heterogeneity in Pediatric IBD. Cellular and Molecular Gastroenterology and Hepatology. 6: 474-476.e3. PMID 30364773 DOI: 10.1016/J.Jcmgh.2018.07.001  0.448
2018 Schirmer M, Denson L, Vlamakis H, Franzosa EA, Thomas S, Gotman NM, Rufo P, Baker SS, Sauer C, Markowitz J, Pfefferkorn M, Oliva-Hemker M, Rosh J, Otley A, Boyle B, et al. Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course. Cell Host & Microbe. 24: 600-610.e4. PMID 30308161 DOI: 10.1016/J.Chom.2018.09.009  0.405
2018 Lindoso L, Mondal K, Venkateswaran S, Somineni HK, Ballengee C, Walters TD, Griffiths A, Noe JD, Crandall W, Snapper S, Rabizadeh S, Rosh JR, LeLeiko N, Guthery S, Mack D, ... ... Denson LA, et al. The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children. The American Journal of Gastroenterology. PMID 30267029 DOI: 10.1038/S41395-018-0239-9  0.424
2018 Kelly D, Kotliar M, Woo V, Jagannathan S, Whitt J, Moncivaiz J, Aronow BJ, Dubinsky MC, Hyams JS, Markowitz JF, Baldassano RN, Stephens MC, Walters TD, Kugathasan S, Haberman Y, ... ... Denson LA, et al. Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. Jci Insight. 3. PMID 30232290 DOI: 10.1172/Jci.Insight.122104  0.412
2018 Ballengee CR, Stidham RW, Liu C, Kim MO, Prince J, Mondal K, Baldassano R, Dubinsky M, Markowitz J, Leleiko N, Hyams J, Denson L, Kugathasan S. Association Between Plasma Level of Collagen Type III alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn's Disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 30213581 DOI: 10.1016/J.Cgh.2018.09.008  0.366
2018 Chen JS, Hu F, Kugathasan S, Jorde LB, Nix D, Rutherford A, Denson L, Watkins WS, Prahalad S, Huff C, Guthery SL. Targeted Gene Sequencing in Children with Crohn's Disease and Their Parents: Implications for Missing Heritability. G3 (Bethesda, Md.). 8: 2881-2888. PMID 30166421 DOI: 10.1534/G3.118.200404  0.422
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Alexander Valencia C, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, et al. Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. PMID 30124884 DOI: 10.1093/Ibd/Izy265  0.729
2018 Romick-Rosendale LE, Haslam DB, Lane A, Denson L, Lake K, Wilkey A, Watanabe M, Bauer S, Litts B, Luebbering N, Dandoy CE, Davies SM. Antibiotic Exposure and Reduced Short Chain Fatty Acid Production after Hematopoietic Stem Cell Transplant. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 30055351 DOI: 10.1016/J.Bbmt.2018.07.030  0.309
2018 Picoraro JA, Lee D, Heller CA, Weaver A, Hyams JS, Conklin LS, Otley A, Ziring D, Kugathasan S, Rosh JR, Mulberg A, Denson LA, Kappelman MD, Grossman AB, Bousvaros A, et al. Pediatric Inflammatory Bowel Disease Clinical Innovations Meeting of the Crohn's & Colitis Foundation: Charting the Future of Pediatric IBD. Inflammatory Bowel Diseases. PMID 29931102 DOI: 10.1093/Ibd/Izy205  0.451
2018 Chandradevan R, Hofmekler T, Mondal K, Harun N, Venkateswaran S, Somineni HK, Ballengee CR, Kim MO, Griffiths A, Noe JD, Crandall WV, Snapper S, Rabizadeh S, Rosh JR, Walters TD, ... ... Denson LA, et al. Evolution of Pediatric Inflammatory Bowel Disease Unclassified (IBD-U): Incorporated With Serological and Gene Expression Profiles. Inflammatory Bowel Diseases. PMID 29860529 DOI: 10.1093/Ibd/Izy136  0.475
2018 Spencer EA, Davis SM, Mack DR, Boyle BM, Griffiths AM, LeLeiko NS, Sauer CG, Keljo DJ, Markowitz JF, Baker SS, Rosh JR, Baldassano RN, Oliva-Hemker M, Pfefferkorn MD, Otley AR, ... ... Denson LA, et al. Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children. Inflammatory Bowel Diseases. PMID 29718391 DOI: 10.1093/Ibd/Izy009  0.452
2018 Shaw KA, Cutler DJ, Okou D, Dodd A, Aronow BJ, Haberman Y, Stevens C, Walters TD, Griffiths A, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Kirschner BS, Heyman MB, ... ... Denson LA, et al. Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort. Genes and Immunity. PMID 29593342 DOI: 10.1038/S41435-018-0015-2  0.743
2018 Venkateswaran S, Prince J, Cutler DJ, Marigorta UM, Okou DT, Prahalad S, Mack D, Boyle B, Walters T, Griffiths A, Sauer CG, LeLeiko N, Keljo D, Markowitz J, Baker SS, ... ... Denson LA, et al. Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis. Inflammatory Bowel Diseases. 24: 829-838. PMID 29562276 DOI: 10.1093/Ibd/Izx084  0.713
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Quinn K, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, et al. Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients with Crohn's Disease. Gastroenterology. PMID 29454792 DOI: 10.1053/J.Gastro.2018.02.016  0.724
2018 Gathungu G, Zhang Y, Tian X, Bonkowski E, Rowehl L, Krumsiek J, Nix B, Chalk C, Trapnell B, Zhu W, Newberry R, Denson L, Li E. Impaired granulocyte-macrophage colony-stimulating factor bioactivity accelerates surgical recurrence in ileal Crohn's disease. World Journal of Gastroenterology. 24: 623-630. PMID 29434451 DOI: 10.3748/Wjg.V24.I5.623  0.395
2018 Gutiérrez M, Scaglia P, Keselman A, Martucci L, Karabatas L, Domené S, Martín A, Pennisi P, Blanco M, Sanguineti N, Bezrodnik L, Di Giovanni D, Caldirola MS, Azcoiti ME, Gaillard MI, ... Denson LA, et al. Partial growth hormone insensitivity and dysregulatory immune disease associated with de novo germline activating STAT3 mutations. Molecular and Cellular Endocrinology. PMID 29378236 DOI: 10.1016/J.Mce.2018.01.016  0.329
2018 Haberman Y, BenShoshan M, Di Segni A, Dexheimer PJ, Braun T, Weiss B, Walters TD, Baldassano RN, Noe JD, Markowitz J, Rosh J, Heyman MB, Griffiths AM, Crandall WV, Mack DR, ... ... Denson LA, et al. Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease. Inflammatory Bowel Diseases. 24: 346-360. PMID 29361088 DOI: 10.1093/Ibd/Izx013  0.383
2018 DeBoer MD, Lee AM, Herbert K, Long J, Thayu M, Griffin LM, Baldassano RN, Denson LA, Zemel BS, Denburg MR, Herskovitz R, Leonard MB. Increases in IGF-1 after Anti-TNF-α Therapy are Associated with Bone and Muscle Accrual in Pediatric Crohn's Disease. The Journal of Clinical Endocrinology and Metabolism. PMID 29329430 DOI: 10.1210/Jc.2017-01916  0.351
2018 Schirmer M, Franzosa EA, Lloyd-Price J, McIver LJ, Schwager R, Poon TW, Ananthakrishnan AN, Andrews E, Barron G, Lake K, Prasad M, Sauk J, Stevens B, Wilson RG, Braun J, ... Denson LA, et al. Dynamics of metatranscription in the inflammatory bowel disease gut microbiome. Nature Microbiology. PMID 29311644 DOI: 10.1038/S41564-017-0089-Z  0.443
2018 Somineni HK, Venkateswaran S, Kilaru V, Chopra P, Okou DT, Hyams JS, Denson LA, Cutler DJ, Gibson G, Conneely KN, Smith AK, Kugathasan S. 10 EPIGENOME-WIDE ASSOCIATION STUDY IDENTIFIED SHARED METHYLOMIC CONTRIBUTIONS TO SUSCEPTIBILITY AND PROGRESSION IN PEDIATRIC CROHN’S DISEASE Inflammatory Bowel Diseases. 24: S71-S71. DOI: 10.1093/ibd/izy038.017  0.707
2018 Haberman Y, BenShoshan M, Segni AD, Dexheimer PJ, Braun T, Weiss B, Avivi C, Barshack I, Anikster Y, Aronow B, Hyams JS, Kugathasan S, Denson LA. DOP015 Dysregulation of cell-type-specific long ncRNA in the ileum of treatment naïve early onset Crohn disease Journal of Crohns & Colitis. 12. DOI: 10.1093/Ecco-Jcc/Jjx180.052  0.348
2018 Somineni HK, Venkateswaran S, Kilaru V, Chopra P, Okou DT, Hyams JS, Denson LA, Cutler DJ, Gibson G, Conneely KN, Smith AK, Kugathasan S. 10 EPIGENOME-WIDE ASSOCIATION STUDY IDENTIFIED SHARED METHYLOMIC CONTRIBUTIONS TO SUSCEPTIBILITY AND PROGRESSION IN PEDIATRIC CROHN'S DISEASE Gastroenterology. 154: S101. DOI: 10.1053/J.Gastro.2017.11.238  0.734
2018 Price AD, Jurickova I, Denson LA. P092 PHYSIOLOGIC HYPOXIA AND LIPID PEROXIDATION PRODUCTS MODULATE GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR-DEPENDENT NEUTROPHIL BACTERIAL KILLING IN PEDIATRIC CROHN’S DISEASE Gastroenterology. 154: S47-S48. DOI: 10.1053/J.Gastro.2017.11.137  0.349
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, Jackson K, et al. 27 CLINICAL AND GENOMIC CORRELATES OF NEUTROPHIL GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR SIGNALING IN PEDIATRIC CROHN DISEASE Inflammatory Bowel Diseases. 24: S7-S8. DOI: 10.1053/J.Gastro.2017.11.051  0.714
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, Jackson K, et al. 27 CLINICAL AND GENOMIC CORRELATES OF NEUTROPHIL GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR SIGNALING IN PEDIATRIC CROHN DISEASE Gastroenterology. 154: S10-S11. DOI: 10.1053/j.gastro.2017.11.051  0.694
2018 Marigorta U, Venkateswaran S, Denson LA, Hyams JS, Gibson G, Kugathasan S. Tu1798 - Transcriptome Variation in Ileal and Rectal Biopsies of Pediatric IBD Patients Gastroenterology. 154: S-1022. DOI: 10.1016/S0016-5085(18)33424-3  0.314
2018 Carmody J, Plevinsky J, Peugh J, Lobato D, Leleiko NS, Hyams JS, Denson LA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Rosh JR, Otley A, Boyle BM, Mack DR, et al. Su2018 - Longitudinal Adherence to Mesalamine in Pediatric Ulcerative Colitis: Results from the Protect Study Gastroenterology. 154: S-667-S-668. DOI: 10.1016/S0016-5085(18)32362-X  0.336
2018 Wu J, Lubman DM, Kugathasan S, Denson LA, Hyams JS, Dubinsky M, Griffiths AM, Baldassano RN, Noe JD, Crandall WV, Higgins PD, Stidham RW. Su1878 - Serum Markers can Predict Future Fibrostenotic Complications at the Time of Diagnosis in Pediatric Crohn's Disease Gastroenterology. 154: S-616-S-617. DOI: 10.1016/S0016-5085(18)32224-8  0.361
2018 Haberman Y, Schirmer M, Dexheimer PJ, Karns R, Braun T, Kim M, Walters TD, Baldassano RN, Noe JD, Rosh JR, Markowitz J, Crandall WV, Mack DR, Griffiths AM, Heyman MB, ... ... Denson LA, et al. 740 - Age-of-Onset Dependent Ileal Immune Maturation and Reduced Alpha-Defensin in Pediatric Crohn Disease with Already Established Dysbiosis Gastroenterology. 154: S-154. DOI: 10.1016/S0016-5085(18)30930-2  0.329
2018 Kelly DR, Kotliar M, Woo V, Jagannathan S, Whitt J, Moncivaiz J, Haberman Y, Barski A, Denson LA, Alenghat T. 635 - Intestinal Microbiota Direct an Epithelial Epigenetic Signature of Pediatric Crohn's Disease Gastroenterology. 154: S-133-S-134. DOI: 10.1016/S0016-5085(18)30872-2  0.422
2018 Schirmer M, Vlamakis H, Denson LA, Franzosa EA, Davis S, Rufo PA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Oliva-Hemker M, Rosh JR, Otley A, Boyle BM, Mack DR, et al. 634 - Gut Microbial Factors Implicated in Disease Progression and Treatment Response in Pediatric Ulcerative Colitis Gastroenterology. 154: S-133. DOI: 10.1016/S0016-5085(18)30871-0  0.417
2018 Haberman Y, Karns R, Dexheimer PJ, Bauman LE, Collins MH, Rosen MJ, Bonkowski E, Marquis A, Gotman N, Rufo PA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Rosh JR, ... ... Denson LA, et al. 589 - The Treatment Naive Rectal Transcriptome Identifies Pathways Mediating Clinical and Endoscopic Severity and Response to Initial Therapy in Pediatric Ulcerative Colitis Gastroenterology. 154: S-124. DOI: 10.1016/S0016-5085(18)30842-4  0.32
2018 Hyams JS, Wang Z, Davis S, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Baldassano RN, Marquis A, Gotman N, Keljo DJ, Rosh JR, Serrano J, Kugathasan S, Markowitz J, ... ... Denson LA, et al. 498 - Defining Remission in Pediatric Ulcerative Colitis: Evidence from the Protect Study Gastroenterology. 154: S-113-S-114. DOI: 10.1016/S0016-5085(18)30815-1  0.355
2018 Jurickova I, Karns R, Cutler DJ, Okou D, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, Jackson K, Walters TD, Griffiths AM, ... ... Denson LA, et al. 378 - Genomic Correlates of Reduced Neutrophil Granulocytemacrophage Colony Stimulating Factor Signaling in Stricturing Pediatric Crohn Disease Gastroenterology. 154: S-89-S-90. DOI: 10.1016/S0016-5085(18)30746-7  0.715
2017 Minar P, Jackson K, Tsai YT, Sucharew H, Rosen MJ, Denson LA. Validation of Neutrophil CD64 Blood Biomarkers to Detect Mucosal Inflammation in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. 24: 198-208. PMID 29272485 DOI: 10.1093/Ibd/Izx022  0.373
2017 Wright SS, Trauernicht A, Bonkowski E, McCall CA, Maier EA, Bezold R, Lake K, Chalk C, Trapnell BC, Kim MO, Kugathasan S, Denson LA. Familial Association of Granulocyte-Macrophage Colony Stimulating Factor Autoantibodies in Inflammatory Bowel Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 29216019 DOI: 10.1097/Mpg.0000000000001851  0.409
2017 Orscheln ES, Dillman JR, Towbin AJ, Denson LA, Trout AT. Penetrating Crohn disease: does it occur in the absence of stricturing disease? Abdominal Radiology (New York). PMID 29167943 DOI: 10.1007/S00261-017-1398-7  0.45
2017 Schwerd T, Bryant RV, Pandey S, Capitani M, Meran L, Cazier JB, Jung J, Mondal K, Parkes M, Mathew CG, Fiedler K, McCarthy DJ, ... ... Denson LA, et al. NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease. Mucosal Immunology. PMID 29091079 DOI: 10.1038/Mi.2017.74  0.37
2017 Kugathasan S, Denson LA, Hyams JS. Exclusive and partial enteral nutrition for Crohn's disease - Authors' reply. Lancet (London, England). 390: 1486-1487. PMID 28952446 DOI: 10.1016/S0140-6736(17)32157-8  0.402
2017 Hyams JS, Davis S, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh J, Baldassano RN, Patel A, Pfefferkorn M, Otley A, ... ... Denson LA, et al. Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study. The Lancet. Gastroenterology & Hepatology. PMID 28939374 DOI: 10.1016/S2468-1253(17)30252-2  0.353
2017 Boyle B, Collins MH, Wang Z, Mack D, Griffiths A, Sauer C, Markowitz J, LeLeiko N, Keljo D, Rosh J, Baker SS, Pfefferkorn M, Heyman M, Patel A, Baldassano R, ... ... Denson L, et al. Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed With Ulcerative Colitis. The American Journal of Surgical Pathology. PMID 28863076 DOI: 10.1097/Pas.0000000000000939  0.361
2017 Marigorta UM, Denson LA, Hyams JS, Mondal K, Prince J, Walters TD, Griffiths A, Noe JD, Crandall WV, Rosh JR, Mack DR, Kellermayer R, Heyman MB, Baker SS, Stephens MC, et al. Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease. Nature Genetics. PMID 28805827 DOI: 10.1038/Ng.3936  0.424
2017 Kugathasan S, Denson LA, Walters TD, Kim MO, Marigorta UM, Schirmer M, Mondal K, Liu C, Griffiths A, Noe JD, Crandall WV, Snapper S, Rabizadeh S, Rosh JR, Shapiro JM, et al. Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study. Lancet (London, England). PMID 28259484 DOI: 10.1016/S0140-6736(17)30317-3  0.383
2017 Rosen MJ, Karns R, Vallance JE, Bezold R, Waddell A, Collins MH, Haberman Y, Minar P, Baldassano RN, Hyams JS, Baker SS, Kellermayer R, Noe JD, Griffiths AM, Rosh JR, ... ... Denson LA, et al. Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-only Crohn's Disease in Treatment-naïve Pediatric Patients. Gastroenterology. PMID 28132889 DOI: 10.1053/J.Gastro.2017.01.016  0.43
2017 Mulgund AA, Bauman L, Chona DL, Sharma P, Su W, Fei L, Denson LA, Minar P, Dykes DM, Rosen MJ. Effect of an Anti-TNF Therapeutic Drug Monitoring Quality Improvement Program on Inflammatory Bowel Disease Patient Outcomes at a Large Academic Pediatric Gastroenterology Practice American Journal of Gastroenterology. 112: S402-S403. DOI: 10.14309/00000434-201710001-00729  0.351
2017 Ballengee CR, Prince J, Baldassano RN, Denson LA, Katz J, Cross RK, Patel AS, Quiros A, Tomer G, Kugathasan S. Procollagen III N-Terminal Propeptide (PIIINP) as a Circulating Biomarker for Active Stricture Development in Pediatric Crohn's Disease Gastroenterology. 152: S956. DOI: 10.1016/S0016-5085(17)33250-X  0.363
2017 Hellmann J, Linn A, Lake K, Bezold R, Fei L, Denson LA. C. Difficile Infection in the First Year After Diagnosis is Associated with Shorter Time to Bowel Resection Surgery in Pediatric Crohn Disease Gastroenterology. 152: S956. DOI: 10.1016/S0016-5085(17)33249-3  0.337
2017 Denson LA, Jurickova I, Shaw K, Linn A, Dodd A, Okou D, Chalk C, Bonkowski E, Griffiths AM, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Heyman MB, Snapper SB, et al. Low Neutrophil Reactive Oxygen Species Production is Associated with Nicotinamide-Adenine Dinucleotide Phosphate (NADPH) Oxidase Gene Mutations and Refractory Colonic Involvement in Pediatric Crohn Disease Gastroenterology. 152: S955. DOI: 10.1016/S0016-5085(17)33247-X  0.689
2017 Denson LA, Jurickova I, Shaw K, Linn A, Dodd A, Okou D, Chalk C, Bonkowski E, Griffiths AM, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Heyman MB, Snapper SB, et al. Reduced Neutrophil Granulocyte-Macrophage Colony Stimulating Factor Signaling is Associated with Granulocyte-Macrophage Colony Stimulating Factor Receptor Alpha Chain Gene Mutations and Stricturing Disease Complications in Pediatric Crohn Disease Gastroenterology. 152: S955. DOI: 10.1016/S0016-5085(17)33246-8  0.712
2017 Prince J, Venkateswaran S, Cutler DJ, Okou D, Chopra P, Davis S, Baker SS, Strople JA, Hommel KA, Evans JS, Sauer CG, Markowitz J, Rufo PA, Pfefferkorn MD, Ziring D, ... ... Denson LA, et al. Greater Contribution of HLA to Risk for Pediatric-Onset Ulcerative Colitis Can be Narrowed to 3 Independent Classic HLA Variants and Corresponding Amino Acid Changes Gastroenterology. 152: S954. DOI: 10.1016/S0016-5085(17)33244-4  0.664
2017 Townsend P, Davis S, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh JR, Baldassano RN, Patel AS, Pfefferkorn MD, Otley A, ... ... Denson LA, et al. Is Mesalamine Monotherapy Equally Effective in Inducing Remission in Mild Versus Moderate Pediatric Ulcerative Colitis at Diagnosis? Gastroenterology. 152: S953. DOI: 10.1016/S0016-5085(17)33242-0  0.328
2017 Schirmer M, Vlamakis H, Denson LA, Davis S, Rufo PA, Baker SS, Strople JA, Sauer CG, Markowitz J, Pfefferkorn MD, Ziring D, Oliva-Hemker M, Sudel B, Rosh JR, Otley A, et al. Microbial Dysbiosis Associated with Disease Severity in Treatment Naive Pediatric Patients with New-Onset Ulcerative Colitis Gastroenterology. 152: S172-S173. DOI: 10.1016/S0016-5085(17)30894-6  0.409
2017 Kugathasan S, Denson LA, Walters TD, Kim M, Marigorta U, Schirmer M, Mondal K, Liu C, Griffiths AM, Noe JD, Crandall WV, Snapper SB, Rabizadeh S, Rosh JR, Shapiro JM, et al. Early Anti-TNF is Effective in Preventing Internal Penetrating but not Stricturing Disease Complications in Children Newly Diagnosed with Crohn's Disease: A Prospective Risk Prediction Model for Disease Behavior Study Gastroenterology. 152: S64. DOI: 10.1016/S0016-5085(17)30569-3  0.422
2016 Minar P, Jackson K, Tsai YT, Rosen MJ, Northcutt M, Khodoun M, Finkelman FD, Denson LA. A Low Neutrophil CD64 Index Is Associated with Sustained Remission During Infliximab Maintenance Therapy. Inflammatory Bowel Diseases. PMID 27749455 DOI: 10.1097/Mib.0000000000000922  0.347
2016 Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, ... ... Denson LA, et al. Genome-wide Association Study Identifies African-Specific Susceptibility Loci in African Americans with Inflammatory Bowel Disease. Gastroenterology. PMID 27693347 DOI: 10.1053/J.Gastro.2016.09.032  0.739
2016 Denson LA, Klein C. Granulocyte-Macrophage Colony Stimulating Factor Bioactivity and Mucosal Homeostasis in Crohn's Disease: A Role for Genetic Variation. Gastroenterology. PMID 27590689 DOI: 10.1053/J.Gastro.2016.08.042  0.396
2016 Moshkovits I, Reichman H, Karo-Atar D, Rozenberg P, Zigmond E, Haberman Y, Ben Baruch-Morgenstern N, Lampinen M, Carlson M, Itan M, Denson LA, Varol C, Munitz A. A key requirement for CD300f in innate immune responses of eosinophils in colitis. Mucosal Immunology. PMID 27118491 DOI: 10.1038/Mi.2016.37  0.39
2016 Stein R, Lee D, Leonard MB, Thayu M, Denson LA, Chuang E, Herskovitz R, Kerbowski T, Baldassano RN. Serum Infliximab, Antidrug Antibodies, and Tumor Necrosis Factor Predict Sustained Response in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. PMID 27057683 DOI: 10.1097/Mib.0000000000000769  0.348
2016 DeBoer MD, Thayu M, Griffin LM, Baldassano RN, Denson LA, Zemel BS, Denburg MR, Agard HE, Herskovitz R, Long J, Leonard MB. Increases in Sex Hormones during Anti-Tumor Necrosis Factor α Therapy in Adolescents with Crohn's Disease. The Journal of Pediatrics. PMID 26873656 DOI: 10.1016/J.Jpeds.2016.01.003  0.362
2016 Gathungu G, Zhang Y, Bonkowski E, Rowehl L, Krumsiek JM, Chalk C, Trapnell B, Kim M, Zhu W, Newberry R, Denson L, Li E. Sa1891 Granulocyte-Macrophage Colony-Stimulating Factor Bioactivity and Time to Surgical Recurrence in Patients with Ileal Crohn Disease Gastroenterology. 150: S394. DOI: 10.1016/S0016-5085(16)31380-4  0.38
2016 Zhang D, Mayhew C, Gilbert S, Bangar H, Cha S, Watson CL, Haslam D, Helmrath M, Moriggl R, Denson L, Wells J, Han X. 32 Cytokine-STAT5 Signaling Controls Intestinal Stem Cell Activation to Suppress Clostridium Difficile - Induced Gut Inflammation Gastroenterology. 150: S11. DOI: 10.1016/S0016-5085(16)30167-6  0.306
2015 Denson LA. Epithelial Reactive Oxygen Species and Risk for Very Early Onset Inflammatory Bowel Disease. Cellular and Molecular Gastroenterology and Hepatology. 1: 456-457. PMID 28210694 DOI: 10.1016/J.Jcmgh.2015.07.002  0.372
2015 Minar P, Saeed SA, Afreen M, Kim MO, Denson LA. Practical Use of Infliximab Concentration Monitoring in Pediatric Crohn's Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 26551317 DOI: 10.1097/Mpg.0000000000001029  0.339
2015 Li YR, Zhao SD, Li J, Bradfield JP, Mohebnasab M, Steel L, Kobie J, Abrams DJ, Mentch FD, Glessner JT, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, ... ... Denson LA, et al. Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nature Communications. 6: 8442. PMID 26450413 DOI: 10.1038/Ncomms9442  0.353
2015 Li YR, Li J, Zhao SD, Bradfield JP, Mentch FD, Maggadottir SM, Hou C, Abrams DJ, Chang D, Gao F, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, ... ... Denson LA, et al. Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nature Medicine. 21: 1018-27. PMID 26301688 DOI: 10.1038/Nm.3933  0.386
2015 Arora K, Sinha C, Zhang W, Moon CS, Ren A, Yarlagadda S, Dostmann WR, Adebiyi A, Haberman Y, Denson LA, Wang X, Naren AP. Altered cGMP Dynamics at the Plasma Membrane Contribute to Diarrhea in Ulcerative Colitis. The American Journal of Pathology. 185: 2790-804. PMID 26261085 DOI: 10.1016/J.Ajpath.2015.06.007  0.322
2015 Cutler DJ, Zwick ME, Okou DT, Prahalad S, Walters T, Guthery SL, Dubinsky M, Baldassano R, Crandall WV, Rosh J, Markowitz J, Stephens M, Kellermayer R, Pfefferkorn M, Heyman MB, ... ... Denson LA, et al. Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping. Plos One. 10: e0128074. PMID 26098103 DOI: 10.1371/Journal.Pone.0128074  0.723
2015 Zhang R, Gilbert S, Yao X, Vallance J, Steinbrecher K, Moriggl R, Zhang D, Eluri M, Chen H, Cao H, Shroyer N, Denson L, Han X. Natural compound methyl protodioscin protects against intestinal inflammation through modulation of intestinal immune responses. Pharmacology Research & Perspectives. 3: e00118. PMID 26038694 DOI: 10.1002/Prp2.118  0.387
2015 Ning K, Gettler K, Zhang W, Ng SM, Bowen BM, Hyams J, Stephens MC, Kugathasan S, Denson LA, Schadt EE, Hoffman GE, Cho JH. Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes. Human Molecular Genetics. 24: 4147-57. PMID 25935003 DOI: 10.1093/Hmg/Ddv142  0.369
2015 Haberman Y, Tickle TL, Dexheimer PJ, Kim MO, Tang D, Karns R, Baldassano RN, Noe JD, Rosh J, Markowitz J, Heyman MB, Griffiths AM, Crandall WV, Mack DR, Baker SS, ... ... Denson LA, et al. Corrigendum. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature. The Journal of Clinical Investigation. 125: 1363. PMID 25729854 DOI: 10.1172/Jci79657  0.42
2015 Gray WN, Boyle SL, Graef DM, Janicke DM, Jolley CD, Denson LA, Baldassano RN, Hommel KA. Health-related quality of life in youth with Crohn disease: role of disease activity and parenting stress. Journal of Pediatric Gastroenterology and Nutrition. 60: 749-53. PMID 25564807 DOI: 10.1097/Mpg.0000000000000696  0.348
2015 Walters TD, Mack DR, Boyle B, Griffiths AM, Sauer C, Leleiko NS, Markowitz J, Keljo DJ, Rosh JR, Baker SS, Heyman MB, Patel AS, Pfefferkorn MD, Baldassano R, Noe JD, ... ... Denson L, et al. Sa1999 Patient Related Outcomes and Disease Activity Indices in New Onset Pediatric Ulcerative Colitis: The PROTECT Study Gastroenterology. 148: S-380. DOI: 10.1016/S0016-5085(15)31273-7  0.316
2014 Haberman Y, Tickle TL, Dexheimer PJ, Kim MO, Tang D, Karns R, Baldassano RN, Noe JD, Rosh J, Markowitz J, Heyman MB, Griffiths AM, Crandall WV, Mack DR, Baker SS, ... ... Denson LA, et al. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature. The Journal of Clinical Investigation. 124: 3617-33. PMID 25003194 DOI: 10.1172/Jci75436  0.365
2014 Okou DT, Mondal K, Faubion WA, Kobrynski LJ, Denson LA, Mulle JG, Ramachandran D, Xiong Y, Svingen P, Patel V, Bose P, Waters JP, Prahalad S, Cutler DJ, Zwick ME, et al. Exome sequencing identifies a novel FOXP3 mutation in a 2-generation family with inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 58: 561-8. PMID 24792626 DOI: 10.1097/Mpg.0000000000000302  0.71
2014 Minar P, Haberman Y, Jurickova I, Wen T, Rothenberg ME, Kim MO, Saeed SA, Baldassano RN, Stephens M, Markowitz J, Rosh J, Crandall WV, Heyman MB, Mack DR, Griffiths AM, ... ... Denson LA, et al. Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease. Inflammatory Bowel Diseases. 20: 1037-48. PMID 24788216 DOI: 10.1097/Mib.0000000000000049  0.425
2014 Gevers D, Kugathasan S, Denson LA, Vázquez-Baeza Y, Van Treuren W, Ren B, Schwager E, Knights D, Song SJ, Yassour M, Morgan XC, Kostic AD, Luo C, González A, McDonald D, et al. The treatment-naive microbiome in new-onset Crohn's disease. Cell Host & Microbe. 15: 382-92. PMID 24629344 DOI: 10.1016/J.Chom.2014.02.005  0.44
2014 Augustine MV, Leonard MB, Thayu M, Baldassano RN, de Boer IH, Shults J, Denson LA, DeBoer MD, Herskovitz R, Denburg MR. Changes in vitamin D-related mineral metabolism after induction with anti-tumor necrosis factor-α therapy in Crohn's disease. The Journal of Clinical Endocrinology and Metabolism. 99: E991-8. PMID 24617709 DOI: 10.1210/Jc.2013-3846  0.341
2014 Crandall WV, Baldassano R, Bousvaros A, Denson LA, Gupta N, Mackner LM. NASPGHAN single-topic symposium: discovering the future of pediatric IBD care. Journal of Pediatric Gastroenterology and Nutrition. 58: 130-8. PMID 24378522 DOI: 10.1097/Mpg.0000000000000178  0.301
2014 Walters TD, Kim MO, Denson LA, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh J, Pfefferkorn M, Otley A, Heyman MB, LeLeiko N, Baker S, Guthery SL, et al. Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease. Gastroenterology. 146: 383-91. PMID 24162032 DOI: 10.1053/J.Gastro.2013.10.027  0.353
2014 Pai AL, Tackett A, Hente EA, Ernst MM, Denson LA, Hommel KA. Assessing psychosocial risk in pediatric inflammatory bowel disease: validation of the Psychosocial Assessment Tool 2.0_General. Journal of Pediatric Gastroenterology and Nutrition. 58: 51-6. PMID 23969535 DOI: 10.1097/Mpg.0B013E3182A938B7  0.383
2014 Gevers D, Kugathasan S, Denson L, Vázquez-Baeza Y, Van Treuren W, Ren B, Schwager E, Knights D, Song SJ, Yassour M, Morgan X, Kostic AD, Luo C, Gonzalez A, McDonald D, et al. 850a The treatment-naive microbiome in early-onset Crohn's Disease Gastroenterology. 146: S-144. DOI: 10.1016/S0016-5085(14)60512-6  0.335
2014 Haberman Y, Tickle TL, Dexheimer PJ, Huttenhower C, Karns R, Baldassano R, Noe JD, Rosh JR, Markowitz J, Heyman MB, Griffiths AM, Crandall W, Mack DR, Baker SS, Hyams JS, ... ... Denson L, et al. 78 Host Ileal APOA1 and DUOX2 Co-Expression Modules Are Associated With Microbial Shifts and Clinical Outcomes in Treatment Naive Pediatric Crohn Disease Gastroenterology. 146: S-22. DOI: 10.1016/S0016-5085(14)60078-0  0.354
2013 Towbin AJ, Sullivan J, Denson LA, Wallihan DB, Podberesky DJ. CT and MR enterography in children and adolescents with inflammatory bowel disease. Radiographics : a Review Publication of the Radiological Society of North America, Inc. 33: 1843-60. PMID 24224581 DOI: 10.1148/Rg.337105140  0.357
2013 Däbritz J, Bonkowski E, Chalk C, Trapnell BC, Langhorst J, Denson LA, Foell D. Granulocyte macrophage colony-stimulating factor auto-antibodies and disease relapse in inflammatory bowel disease. The American Journal of Gastroenterology. 108: 1901-10. PMID 24145675 DOI: 10.1038/Ajg.2013.360  0.434
2013 Ryan JL, Mellon MW, Junger KW, Hente EA, Denson LA, Saeed SA, Hommel KA. The clinical utility of health-related quality of life screening in a pediatric inflammatory bowel disease clinic. Inflammatory Bowel Diseases. 19: 2666-72. PMID 24051932 DOI: 10.1097/Mib.0B013E3182A82B15  0.357
2013 Dykes DM, Towbin AJ, Bonkowski E, Chalk C, Bezold R, Lake K, Kim MO, Heubi JE, Trapnell BC, Podberesky DJ, Denson LA. Increased prevalence of luminal narrowing and stricturing identified by enterography in pediatric Crohn's disease patients with elevated granulocyte-macrophage colony stimulating factor autoantibodies. Inflammatory Bowel Diseases. 19: 2146-54. PMID 23893081 DOI: 10.1097/Mib.0B013E31829706E0  0.382
2013 Wu YP, Pai AL, Gray WN, Denson LA, Hommel KA. Development and reliability of a correction factor for family-reported medication adherence: pediatric inflammatory bowel disease as an exemplar. Journal of Pediatric Psychology. 38: 893-901. PMID 23804406 DOI: 10.1093/Jpepsy/Jst043  0.303
2013 Gathungu G, Kim MO, Ferguson JP, Sharma Y, Zhang W, Ng SM, Bonkowski E, Ning K, Simms LA, Croft AR, Stempak JM, Walker N, Huang N, Xiao Y, Silverberg MS, ... ... Denson LA, et al. Granulocyte-macrophage colony-stimulating factor autoantibodies: a marker of aggressive Crohn's disease. Inflammatory Bowel Diseases. 19: 1671-80. PMID 23749272 DOI: 10.1097/Mib.0B013E318281F506  0.412
2013 Denson LA. The role of the innate and adaptive immune system in pediatric inflammatory bowel disease. Inflammatory Bowel Diseases. 19: 2011-20. PMID 23702804 DOI: 10.1097/Mib.0B013E318281F590  0.448
2013 Jurickova I, Collins MH, Chalk C, Seese A, Bezold R, Lake K, von Allmen D, Frischer JS, Falcone RA, Trapnell BC, Denson LA. Paediatric Crohn disease patients with stricturing behaviour exhibit ileal granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibody production and reduced neutrophil bacterial killing and GM-CSF bioactivity. Clinical and Experimental Immunology. 172: 455-65. PMID 23600834 DOI: 10.1111/Cei.12076  0.337
2013 Waddell A, Ahrens R, Tsai YT, Sherrill JD, Denson LA, Steinbrecher KA, Hogan SP. Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice. Journal of Immunology (Baltimore, Md. : 1950). 190: 4773-85. PMID 23562811 DOI: 10.4049/Jimmunol.1200057  0.382
2013 DeBoer MD, Denson LA. Delays in puberty, growth, and accrual of bone mineral density in pediatric Crohn's disease: despite temporal changes in disease severity, the need for monitoring remains. The Journal of Pediatrics. 163: 17-22. PMID 23522861 DOI: 10.1016/J.Jpeds.2013.02.010  0.422
2013 Willson TA, Jurickova I, Collins M, Denson LA. Deletion of intestinal epithelial cell STAT3 promotes T-lymphocyte STAT3 activation and chronic colitis following acute dextran sodium sulfate injury in mice. Inflammatory Bowel Diseases. 19: 512-25. PMID 23429443 DOI: 10.1097/Mib.0B013E31828028Ad  0.625
2013 Hommel KA, Hente E, Herzer M, Ingerski LM, Denson LA. Telehealth behavioral treatment for medication nonadherence: a pilot and feasibility study. European Journal of Gastroenterology & Hepatology. 25: 469-73. PMID 23325274 DOI: 10.1097/Meg.0B013E32835C2A1B  0.321
2013 Nylund CM, Goudie A, Garza JM, Crouch G, Denson LA. Venous thrombotic events in hospitalized children and adolescents with inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 56: 485-91. PMID 23232326 DOI: 10.1097/Mpg.0B013E3182801E43  0.378
2013 Minar P, Jurickova I, Haberman Y, Kim M, Saeed SA, Hyams JS, Heyman MB, Kugathasan S, Denson L. Tu1940 Neutrophil FCy Receptor 1 (CD64) Index As a Non-Invasive Biomarker for Clinical and Mucosal Disease Activity in Pediatric Inflammatory Bowel Disease Gastroenterology. 144: S-886. DOI: 10.1016/S0016-5085(13)63296-5  0.441
2013 Däbritz J, Bonkowski EL, Langhorst J, Denson L, Foell D. Tu1120 Granulocyte-Macrophage Colony Stimulating Factor Autoantibodies and Disease Relapse in Inflammatory Bowel Disease Gastroenterology. 144: S-767. DOI: 10.1016/S0016-5085(13)62836-X  0.448
2013 Haberman Y, Jurrickova I, Dexheimer PJ, Karrns R, Tang D, Bonkowski EL, Fey B, Noe JD, Markowitz J, Heyman MB, Crandall W, Snapper SB, Kellermayer R, Kappelman M, Rosh JR, ... ... Denson L, et al. Mo1975 Ileal RNA-Seq Analyses Reveal Decreased Mucosal Myeloid Cell Immune Responses in Pediatric Crohn Disease Patients With Phagocyte Dysfunction Due to Neutralizing Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Auto-Antibodies Gastroenterology. 144: S-708-S-709. DOI: 10.1016/S0016-5085(13)62627-X  0.356
2013 Patel MG, Gathungu G, Denson L, Coe C, Dickstein A, Zhang CK, Ning K, Sharma Y, Radford-Smith G, Bowen BM, Cho JH. Mo1245 Longitudinal Phenotype Analysis Provides Key Support for the Use of GMCSF As a Biomarker for Stricturing Disease Gastroenterology. 144: S-616. DOI: 10.1016/S0016-5085(13)62278-7  0.363
2013 Kugathasan S, Dubinsky M, Guthery SL, Okou DT, Bose P, Zwick ME, Cutler DJ, Waters JP, Hyams JS, Baldassano R, Stephens MC, Heyman MB, Griffiths AM, Crandall W, Markowitz J, ... ... Denson L, et al. 976 Early Onset Crohn's Disease Exhibit Distinct Allele Architecture Differences and Reveal New IBD Loci Gastroenterology. 144: S-178. DOI: 10.1016/S0016-5085(13)60634-4  0.715
2013 Haberman Y, Dexheimer PJ, Karns R, Tang D, Fey B, Bonkowski EL, Griffiths AM, Hyams JS, Kugathasan S, Ziring D, Evans J, Baker SS, Mack DR, Moulton DE, Keljo DJ, ... ... Denson L, et al. 834 Ileal Transcriptome Analysis Reveals Mucosal Immune Maturation With Increasing Age-of-Onset in Pediatric Crohn Disease and Healthy Controls - A Mucosal Gene Expression Based Signature That Supports the Paris Classification for Age-of-Onset Gastroenterology. 144: S-147-S-148. DOI: 10.1016/S0016-5085(13)60529-6  0.368
2013 Hyams JS, Kim M, Denson L, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh JR, Pfefferkorn MD, Otley AR, Heyman MB, Leleiko NS, Baker SS, Guthery SL, et al. 829 Early Anti-TNFα Therapy Is Superior to Early Immunomodulator Therapy in Newly Diagnosed Children With Crohn's Disease Gastroenterology. 144: S-146. DOI: 10.1016/S0016-5085(13)60524-7  0.332
2013 Hogan SP, Ahrens R, Tsai YT, Denson L, Steinbrecher KA, Waddell A. 26 Calprotectin:RAGE:NFkB Axis Regulates Macrophage-Derived CCL11 and Eosinophilic Inflammation in Experimental Colitis Gastroenterology. 144: S-7. DOI: 10.1016/S0016-5085(13)60022-0  0.31
2012 Samson CM, Morgan P, Williams E, Beck L, Addie-Carson R, McIntire S, Booth A, Mendez E, Luzader C, Tomer G, Saeed S, Donovan E, Bucuvalas J, Denson LA. Improved outcomes with quality improvement interventions in pediatric inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 55: 679-88. PMID 22699837 DOI: 10.1097/Mpg.0B013E318262De16  0.333
2012 Rosen MJ, Denson LA, Kugathasan S. Commentaries on "Workshop report: developing a pediatric inflammatory bowel diseases network and data platform in Canada": pediatric inflammatory bowel disease networks: raising the bar. Journal of Pediatric Gastroenterology and Nutrition. 55: 121-2. PMID 22659890 DOI: 10.1097/Mpg.0B013E3182605070  0.399
2012 Wallihan DB, Towbin AJ, Denson LA, Salisbury S, Podberesky DJ. Inflammatory bowel disease in children and adolescents: assessing the diagnostic performance and interreader agreement of magnetic resonance enterography compared to histopathology. Academic Radiology. 19: 819-26. PMID 22520509 DOI: 10.1016/J.Acra.2012.02.023  0.349
2012 Rufo PA, Denson LA, Sylvester FA, Szigethy E, Sathya P, Lu Y, Wahbeh GT, Sena LM, Faubion WA. Health supervision in the management of children and adolescents with IBD: NASPGHAN recommendations. Journal of Pediatric Gastroenterology and Nutrition. 55: 93-108. PMID 22516861 DOI: 10.1097/Mpg.0B013E31825959B8  0.386
2012 Denson LA. How does knowledge from translational research impact our clinical care of pediatric inflammatory bowel disease patients? Current Gastroenterology Reports. 14: 275-81. PMID 22422506 DOI: 10.1007/S11894-012-0258-4  0.423
2012 Chernoguz A, Crawford K, Vandersall A, Rao M, Willson T, Denson LA, Frischer JS. Pretreatment with anti-VEGF therapy may exacerbate inflammation in experimental acute colitis. Journal of Pediatric Surgery. 47: 347-54. PMID 22325388 DOI: 10.1016/J.Jpedsurg.2011.11.028  0.631
2012 Gilbert S, Zhang R, Denson L, Moriggl R, Steinbrecher K, Shroyer N, Lin J, Han X. Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation. Embo Molecular Medicine. 4: 109-24. PMID 22228679 DOI: 10.1097/00054725-201112002-00266  0.331
2012 Willson TA, Kuhn BR, Jurickova I, Gerad S, Moon D, Bonkowski E, Carey R, Collins MH, Xu H, Jegga AG, Guthery SL, Denson LA. STAT3 genotypic variation and cellular STAT3 activation and colon leukocyte recruitment in pediatric Crohn disease. Journal of Pediatric Gastroenterology and Nutrition. 55: 32-43. PMID 22197944 DOI: 10.1097/Mpg.0B013E318246Be78  0.632
2012 Gray WN, Denson LA, Baldassano RN, Hommel KA. Treatment adherence in adolescents with inflammatory bowel disease: the collective impact of barriers to adherence and anxiety/depressive symptoms. Journal of Pediatric Psychology. 37: 282-91. PMID 22080456 DOI: 10.1093/Jpepsy/Jsr092  0.324
2012 Hommel KA, Hente EA, Odell S, Herzer M, Ingerski LM, Guilfoyle SM, Denson LA. Evaluation of a group-based behavioral intervention to promote adherence in adolescents with inflammatory bowel disease. European Journal of Gastroenterology & Hepatology. 24: 64-9. PMID 21989119 DOI: 10.1097/Meg.0B013E32834D09F1  0.335
2012 Huff CD, Witherspoon DJ, Zhang Y, Gatenbee C, Denson LA, Kugathasan S, Hakonarson H, Whiting A, Davis CT, Wu W, Xing J, Watkins WS, Bamshad MJ, Bradfield JP, Bulayeva K, et al. Crohn's disease and genetic hitchhiking at IBD5. Molecular Biology and Evolution. 29: 101-11. PMID 21816865 DOI: 10.1093/Molbev/Msr151  0.314
2012 D'Mello S, Trauernicht A, Ryan A, Bonkowski E, Willson T, Trapnell BC, Frank SJ, Kugasathan S, Denson LA. Innate dysfunction promotes linear growth failure in pediatric Crohn's disease and growth hormone resistance in murine ileitis. Inflammatory Bowel Diseases. 18: 236-45. PMID 21337672 DOI: 10.1002/Ibd.21689  0.638
2012 Guilfoyle SM, Denson LA, Baldassano RN, Hommel KA. Paediatric parenting stress in inflammatory bowel disease: Application of the Pediatric Inventory for Parents Child: Care, Health and Development. 38: 273-279. DOI: 10.1111/J.1365-2214.2010.01200.X  0.321
2012 Chernoguz A, Falcone R, Nathan JD, Saeed SA, Denson L, von Allmen D, Frischer J. Su1518 Role of Fecal Diversion in Pediatric Colorectal Crohn's Disease in the Era of Anti-TNF-a Therapy Gastroenterology. 142: S-1053-S-1054. DOI: 10.1016/S0016-5085(12)64086-4  0.398
2012 Kugathasan S, Dhere TA, Saeed SA, Denson L, Cross R, Landers CJ, McGovern DP, Walters TD, Dubinsky M. Su1914 Unique Antimicrobial and Genetic Profiles in African Americans With Crohn's Disease Suggest Underlying Mechanistic Differences Gastroenterology. 142: S-535. DOI: 10.1016/S0016-5085(12)62053-8  0.344
2012 Melmed G, Siegel CA, Spiegel BM, Allen JI, Cima RR, Colombel J, Dassopoulos T, Denson L, Dudley-Brown S, Garb A, Hanauer SB, Kappelman M, Lewis JD, Lynch I, Moynihan A, et al. Sa1295 Development of Process and Outcome Quality Indicators for Inflammatory Bowel Disease (IBD) Gastroenterology. 142: S-266. DOI: 10.1016/S0016-5085(12)61002-6  0.382
2012 Dykes DM, Podberesky D, Towbin AJ, Denson L. 1150 Increased Prevalence of Strictures and Luminal Narrowing Identified by Enterography in Pediatric Crohn's Disease Patients With Elevated Granulocyte-Macrophage Colony-Stimulating Factor Auto-Antibodies Gastroenterology. 142: S-209. DOI: 10.1016/S0016-5085(12)60783-5  0.393
2012 Jurickova I, Chalk C, Bonkowski EL, Trapnell BC, Denson L. 143 Pediatric Crohn Disease Patients Who Require Ileal Resection Exhibit Increased Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Neutralizing Capacity in Peripheral Blood and GM-CSF Auto-Antibody Production by Ileal Lamina Propria Cells Gastroenterology. 142: S-37. DOI: 10.1016/S0016-5085(12)60143-7  0.353
2012 Walters TD, Dubinsky M, Griffiths AM, Baldassano R, Hyams JS, Stephens MC, Markowitz J, Crandall W, Heyman MB, Kellermayer R, Mack DR, Oliva-Hemker M, Patel AS, Kirschner BS, Moulton DE, ... ... Denson L, et al. 140 Anti-Microbial Serology Patterns in 824 Children With Newly Diagnosed Crohn's Disease: Association With GM-CSF Auto-Antibodies and Specific Clinical Phenotypes Gastroenterology. 142: S-36-S-37. DOI: 10.1016/S0016-5085(12)60140-1  0.378
2012 Hyams JS, Kim M, Denson L, Stephens MC, Markowitz J, Griffiths AM, Crandall W, Essers JB, Baldassano R, Dubinsky M, Rosh JR, Pfefferkorn MD, Kim SC, Otley AR, Kellermayer R, et al. 138 Effect of Deep Ulceration at Diagnostic Colonoscopy on Initial Therapy and One Year Outcome in Children With Crohn's Disease Gastroenterology. 142: S-36. DOI: 10.1016/S0016-5085(12)60138-3  0.351
2011 Ueno PM, Oriá RB, Maier EA, Guedes M, de Azevedo OG, Wu D, Willson T, Hogan SP, Lima AA, Guerrant RL, Polk DB, Denson LA, Moore SR. Alanyl-glutamine promotes intestinal epithelial cell homeostasis in vitro and in a murine model of weanling undernutrition. American Journal of Physiology. Gastrointestinal and Liver Physiology. 301: G612-22. PMID 21799183 DOI: 10.1152/Ajpgi.00531.2010  0.613
2011 Muise AM, Walters T, Xu W, Shen-Tu G, Guo CH, Fattouh R, Lam GY, Wolters VM, Bennitz J, van Limbergen J, Renbaum P, Kasirer Y, Ngan BY, Turner D, Denson LA, et al. Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis. Gastroenterology. 141: 633-41. PMID 21684284 DOI: 10.1053/J.Gastro.2011.04.057  0.422
2011 Gray WN, Denson LA, Baldassano RN, Hommel KA. Disease activity, behavioral dysfunction, and health-related quality of life in adolescents with inflammatory bowel disease. Inflammatory Bowel Diseases. 17: 1581-6. PMID 21674715 DOI: 10.1002/Ibd.21520  0.372
2011 Hommel KA, Herzer M, Ingerski LM, Hente E, Denson LA. Individually tailored treatment of medication nonadherence. Journal of Pediatric Gastroenterology and Nutrition. 53: 435-9. PMID 21519282 DOI: 10.1097/Mpg.0B013E3182203A91  0.315
2011 Nylund CM, D'Mello S, Kim MO, Bonkowski E, Däbritz J, Foell D, Meddings J, Trapnell BC, Denson LA. Granulocyte macrophage-colony-stimulating factor autoantibodies and increased intestinal permeability in Crohn disease. Journal of Pediatric Gastroenterology and Nutrition. 52: 542-8. PMID 21502824 DOI: 10.1097/Mpg.0B013E3181Fe2D93  0.42
2011 Hommel KA, Denson LA, Baldassano RN. Oral medication adherence and disease severity in pediatric inflammatory bowel disease. European Journal of Gastroenterology & Hepatology. 23: 250-4. PMID 21304318 DOI: 10.1097/Meg.0B013E328344019C  0.414
2011 Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, ... ... Denson LA, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genetics. 43: 246-52. PMID 21297633 DOI: 10.1038/Ng.764  0.418
2011 Herzer M, Denson LA, Baldassano RN, Hommel KA. Patient and parent psychosocial factors associated with health-related quality of life in pediatric inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 52: 295-9. PMID 21297508 DOI: 10.1097/Mpg.0B013E3181F5714E  0.334
2011 Herzer M, Denson LA, Baldassano RN, Hommel KA. Family functioning and health-related quality of life in adolescents with pediatric inflammatory bowel disease. European Journal of Gastroenterology & Hepatology. 23: 95-100. PMID 21079514 DOI: 10.1097/Meg.0B013E3283417Abb  0.306
2011 Dotson JL, Crandall W, Mousa H, Honegger JR, Denson L, Samson C, Cunningham D, Balint J, Dienhart M, Jaggi P, Carvalho R. Presentation and outcome of histoplasmosis in pediatric inflammatory bowel disease patients treated with antitumor necrosis factor alpha therapy: a case series. Inflammatory Bowel Diseases. 17: 56-61. PMID 20645322 DOI: 10.1002/Ibd.21378  0.348
2011 Crandall W, Kappelman MD, Colletti RB, Leibowitz I, Grunow JE, Ali S, Baron HI, Berman JH, Boyle B, Cohen S, del Rosario F, Denson LA, Duffy L, Integlia MJ, Kim SC, et al. ImproveCareNow: The development of a pediatric inflammatory bowel disease improvement network. Inflammatory Bowel Diseases. 17: 450-7. PMID 20602466 DOI: 10.1002/Ibd.21394  0.339
2011 Denson L, Walters T, Bonkowski E, Fey B, Mack D, Griffiths A. Innate dysregulation and growth failure in Pediatric Crohn Disease Inflammatory Bowel Diseases. 17: S4-S5. DOI: 10.1097/00054725-201112002-00010  0.364
2011 Vandersall A, Chernoguz A, Crawford K, Donovan E, Willson T, Denson L, Frischer J. Vascular endothelial growth factor inhibition is antiangiogenic in a murine model of acute colitis. Inflammatory Bowel Diseases. 17: S26-S26. DOI: 10.1093/Ibd/17.Supplement1.S26  0.588
2011 Willson T, Jurickova I, Samson CM, Denson L. Deletion of Intestinal Epithelial Cell STAT3 Promotes Chronic Colitis Following Acute Dextran Sodium Sulfate Injury in Mice Gastroenterology. 140: S-845. DOI: 10.1016/S0016-5085(11)63508-7  0.611
2011 Trauernicht A, D'Mello S, Bonkowski EL, Fey B, Trapnell BC, Denson L. Genetic Variation in Interleukin 27 and Janus Associated Kinase 2 is Associated With Granulocyte-Macrophage Colony Stimulating Factor Auto-Antibodies in Pediatric Crohn's Disease Gastroenterology. 140: S-78-S-79. DOI: 10.1016/S0016-5085(11)60317-X  0.389
2011 Jurickova I, Chalk C, Trapnell BC, Denson L. Granulocyte-Macrophage Colony Stimulating Factor Auto-Antibodies Are Produced by Lamina Propria Mononuclear Cells Isolated From Ileal Strictures of Pediatric Patients With Crohn Disease Undergoing Ileo-Cecal Resection Gastroenterology. 140: S-2. DOI: 10.1016/S0016-5085(11)60006-1  0.306
2011 Kuhn B, Jurickova I, Guthery SL, Denson L. The Inflammatory Bowel Disease (IBD) Signal Transducer and Activator of Transcription 3(STAT3) Risk Allele is Associated With Increased Interleukin-6(IL-6)/STAT3 Activation in Epstein-Barr Virus(EBV) Transformed B Lymphocytes From Pediatric IBD Patients Gastroenterology. 140: S-1-S-2. DOI: 10.1016/S0016-5085(11)60005-X  0.383
2010 Lawal TA, Frischer JS, Falcone RA, Chatoorgoon K, Denson LA, Levitt MA. The transanal approach with laparoscopy or laparotomy for the treatment of rectal strictures in Crohn's disease. Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. 20: 791-5. PMID 20874230 DOI: 10.1089/Lap.2009.0470  0.316
2010 Denson LA, Kim MO, Bezold R, Carey R, Osuntokun B, Nylund C, Willson T, Bonkowski E, Li D, Ballard E, Collins M, Moyer MS, Klein DJ. A randomized controlled trial of growth hormone in active pediatric Crohn disease. Journal of Pediatric Gastroenterology and Nutrition. 51: 130-9. PMID 20453679 DOI: 10.1097/Mpg.0B013E3181C992D6  0.664
2010 Thayu M, Denson LA, Shults J, Zemel BS, Burnham JM, Baldassano RN, Howard KM, Ryan A, Leonard MB. Determinants of changes in linear growth and body composition in incident pediatric Crohn's disease. Gastroenterology. 139: 430-8. PMID 20417635 DOI: 10.1053/J.Gastro.2010.04.044  0.357
2010 Munitz A, Cole ET, Beichler A, Groschwitz K, Ahrens R, Steinbrecher K, Willson T, Han X, Denson L, Rothenberg ME, Hogan SP. Paired immunoglobulin-like receptor B (PIR-B) negatively regulates macrophage activation in experimental colitis. Gastroenterology. 139: 530-41. PMID 20398663 DOI: 10.1053/J.Gastro.2010.04.006  0.65
2010 Wang K, Baldassano R, Zhang H, Qu HQ, Imielinski M, Kugathasan S, Annese V, Dubinsky M, Rotter JI, Russell RK, Bradfield JP, Sleiman PM, Glessner JT, Walters T, Hou C, ... ... Denson L, et al. Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Human Molecular Genetics. 19: 2059-67. PMID 20176734 DOI: 10.1093/Hmg/Ddq078  0.422
2010 Pasternak BA, D'Mello S, Jurickova II, Han X, Willson T, Flick L, Petiniot L, Uozumi N, Divanovic S, Traurnicht A, Bonkowski E, Kugathasan S, Karp CL, Denson LA. Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn's disease and murine colitis. Inflammatory Bowel Diseases. 16: 856-69. PMID 19924809 DOI: 10.1002/Ibd.21132  0.677
2010 Ingerski LM, Baldassano RN, Denson LA, Hommel KA. Barriers to oral medication adherence for adolescents with inflammatory bowel disease. Journal of Pediatric Psychology. 35: 683-91. PMID 19776229 DOI: 10.1093/Jpepsy/Jsp085  0.357
2010 Jurickova I, Willson T, Gerad S, Denson L. M1791 The Inflammatory Bowel Disease JAK2 and STAT3 Risk Alleles are Associated With Divergent Effects Upon IL-6 Signaling in Lymphocytes Gastroenterology. 138: S-420. DOI: 10.1016/S0016-5085(10)61934-8  0.663
2010 Safdi A, D'Mello S, Walters TD, Griffiths AM, Denson L. S2003 Serum Vitamin D Level and Disease Activity in Pediatric Inflammatory Bowel Disease Gastroenterology. 138: S-299. DOI: 10.1016/S0016-5085(10)61374-1  0.349
2010 Gathungu G, Ferguson JP, Silverberg MS, Trapnell B, Denson L, Cho JH, Radford-Smith GL. S1173 Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies in Crohn's Disease Gastroenterology. 138: S-196. DOI: 10.1016/S0016-5085(10)60889-X  0.386
2010 Nylund CM, D'Mello S, Bonkowski EL, Däbritz J, Foell D, Meddings J, Trapnell B, Denson L. 755 Granulocyte-Macrophage Colony Stimulating Factor Auto-Antibodies and Intestinal Permeability in Crohn's Disease Gastroenterology. 138: S-104. DOI: 10.1016/S0016-5085(10)60476-3  0.401
2010 Crandall W, Kappelman M, Colletti RB, Denson L, Duffy LF, Grunow J, Kim SC, Leibowitz I, Patel AS, Schoen BT, Tomer G, Milov DE, Cohen SA, Margolis P. 151 Improved Outcomes in a Quality Improvement Collaborative for Pediatric Ulcerative Colitis Gastroenterology. 138: S-29. DOI: 10.1016/S0016-5085(10)60134-5  0.347
2009 Nylund C, Denson L. Analysis of secular trends and impact of Clostridium difficile in hospitalized children with inflammatory bowel disease: O-0001. Inflammatory Bowel Diseases. 15. PMID 21157881 DOI: 10.1002/Ibd.21172  0.348
2009 Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, ... ... Denson L, et al. Common variants at five new loci associated with early-onset inflammatory bowel disease. Nature Genetics. 41: 1335-40. PMID 19915574 DOI: 10.1038/Ng.489  0.389
2009 Colletti RB, Baldassano RN, Milov DE, Margolis PA, Bousvaros A, Crandall WV, Crissinger KD, D'Amico MA, Day AS, Denson LA, Dubinsky M, Ebach DR, Hoffenberg EJ, Kader HA, Keljo DJ, et al. Variation in care in pediatric Crohn disease. Journal of Pediatric Gastroenterology and Nutrition. 49: 297-303. PMID 19590456 DOI: 10.1097/Mpg.0B013E3181919695  0.362
2009 Tomer G, Wetzler G, Keddache M, Denson LA. Polymorphisms in the IBD5 locus are associated with Crohn disease in pediatric Ashkenazi Jewish patients. Journal of Pediatric Gastroenterology and Nutrition. 48: 531-7. PMID 19412005 DOI: 10.1097/Mpg.0B013E318183138A  0.365
2009 Wang K, Zhang H, Kugathasan S, Annese V, Bradfield JP, Russell RK, Sleiman PM, Imielinski M, Glessner J, Hou C, Wilson DC, Walters T, Kim C, Frackelton EC, Lionetti P, ... ... Denson L, et al. Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. American Journal of Human Genetics. 84: 399-405. PMID 19249008 DOI: 10.1016/J.Ajhg.2009.01.026  0.344
2009 Han X, Uchida K, Jurickova I, Koch D, Willson T, Samson C, Bonkowski E, Trauernicht A, Kim MO, Tomer G, Dubinsky M, Plevy S, Kugathsan S, Trapnell BC, Denson LA. Granulocyte-macrophage colony-stimulating factor autoantibodies in murine ileitis and progressive ileal Crohn's disease. Gastroenterology. 136: 1261-71, e1-3. PMID 19230854 DOI: 10.1053/J.Gastro.2008.12.046  0.659
2009 Willson T, Jurickova I, Gerad S, Bonkowski E, Carey R, Denson L. Genotypic variation in STAT3 is associated with Increased Cellular STAT3 Activation and up-regulation of Colonic Leukocyte Recruitment Genes in Crohnʼs Disease Inflammatory Bowel Diseases. 15: S56-S57. DOI: 10.1097/00054725-200912002-00178  0.638
2009 Han X, Gilbert S, Jurickova I, Samson CM, Gully J, Willson T, Denson L. 498 Autocrine Intestinal Epithelial Cell GM-CSF Signaling Promotes Homeostatic Responses to Gut Injury Gastroenterology. 136: A-81. DOI: 10.1016/S0016-5085(09)60364-4  0.655
2009 D'Mello S, Trauernicht A, Bonkowski EL, Willson T, Kugathasan S, Denson L. 73 Innate Dysfunction and Linear Growth Failure in Pediatric Crohn Disease Gastroenterology. 136: A-13. DOI: 10.1016/S0016-5085(09)60063-9  0.649
2008 Denson LA. Growth hormone therapy in children and adolescents: pharmacokinetic/pharmacodynamic considerations and emerging indications. Expert Opinion On Drug Metabolism & Toxicology. 4: 1569-80. PMID 19040332 DOI: 10.1517/17425250802465347  0.322
2008 Ahrens R, Waddell A, Seidu L, Blanchard C, Carey R, Forbes E, Lampinen M, Wilson T, Cohen E, Stringer K, Ballard E, Munitz A, Xu H, Lee N, Lee JJ, ... ... Denson L, et al. Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis. Journal of Immunology (Baltimore, Md. : 1950). 181: 7390-9. PMID 18981162 DOI: 10.4049/Jimmunol.181.10.7390  0.443
2008 Hommel KA, Mackner LM, Denson LA, Crandall WV. Treatment regimen adherence in pediatric gastroenterology. Journal of Pediatric Gastroenterology and Nutrition. 47: 526-43. PMID 18955858 DOI: 10.1097/Mpg.0B013E318175Dda1  0.413
2008 Kugathasan S, Baldassano RN, Bradfield JP, Sleiman PM, Imielinski M, Guthery SL, Cucchiara S, Kim CE, Frackelton EC, Annaiah K, Glessner JT, Santa E, Willson T, Eckert AW, Bonkowski E, ... ... Denson LA, et al. Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nature Genetics. 40: 1211-5. PMID 18758464 DOI: 10.1038/Ng.203  0.688
2008 Peterson N, Guthery S, Denson L, Lee J, Saeed S, Prahalad S, Biank V, Ehlert R, Tomer G, Grand R, Rudolph C, Kugathasan S. Genetic variants in the autophagy pathway contribute to paediatric Crohn's disease. Gut. 57: 1336-7; author reply. PMID 18719149 DOI: 10.1136/Gut.2008.152207  0.371
2008 Carey R, Jurickova I, Ballard E, Bonkowski E, Han X, Xu H, Denson LA. Activation of an IL-6:STAT3-dependent transcriptome in pediatric-onset inflammatory bowel disease. Inflammatory Bowel Diseases. 14: 446-57. PMID 18069684 DOI: 10.1002/Ibd.20342  0.396
2008 Han X, Jurickova I, Bonkowski E, Willson T, Samson C, Trapnell B, Denson L. GM-CSF bioactivity regulates susceptibility to ileal Crohn disease and experimental ileitis: O-020. Inflammatory Bowel Diseases. 14. DOI: 10.1097/00054725-200801001-00020  0.651
2008 Peterson N, Guthery SL, Denson L, Lee JJ, Saeed S, Biank VF, Ehlert R, Tomer G, Grand RJ, Rudolph CD, Kugathasan S. M2053 Autophagy Like Genes (ATG16L1 & IRGM), IL23R and Three Other Variants Are Associated with Pediatric Onset Crohn's Disease (CD) with Similar Risks (Odds Ratio) to Adult Onset Gastroenterology. 134: A-459. DOI: 10.1016/S0016-5085(08)62146-0  0.392
2008 Han X, Jurickova I, Willson T, Samson CM, Bonkowski E, Trapnell B, Denson L. 521 GM-CSF Signaling in Intestinal Epithelial Cells Regulates Ileal Barrier Function Gastroenterology. 134: A-73. DOI: 10.1016/S0016-5085(08)60345-5  0.619
2008 Han X, Jurickova I, Koch D, Willson T, Samson C, Kim M, Kugathsan S, Trapnell B, Denson L. Sa.122. GM-CSF Autoantibodies and Intestinal Homeostasis in Crohn's Disease Clinical Immunology. 127: S120. DOI: 10.1016/J.Clim.2008.03.343  0.693
2007 Han X, Benight N, Osuntokun B, Loesch K, Frank SJ, Denson LA. Tumour necrosis factor α blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis Gut. 56: 73-81. PMID 16777921 DOI: 10.1136/Gut.2006.094490  0.338
2007 Hogan S, Luqman S, Ahrens R, Ballard E, Rothenberg M, Denson L. Eosinophils and eosinophil chemokines, CCL11, CCL24 and CCL26, in refractory pediatric Crohnʼs Disease Inflammatory Bowel Diseases. 13: 645. DOI: 10.1097/00054725-200705001-00010  0.419
2007 Han X, Jurickova I, Carey R, Benight N, Denson L. STAT5B maintains gut mucosal tolerance in Crohnʼs disease and murine colitis Inflammatory Bowel Diseases. 13: 643-644. DOI: 10.1097/00054725-200705001-00004  0.319
2006 Han X, Osuntokun B, Benight N, Loesch K, Frank SJ, Denson LA. Signal transducer and activator of transcription 5b promotes mucosal tolerance in pediatric Crohn's disease and murine colitis. The American Journal of Pathology. 169: 1999-2013. PMID 17148664 DOI: 10.2353/Ajpath.2006.060186  0.375
2006 Konikoff MR, Denson LA. Role of fecal calprotectin as a biomarker of intestinal inflammation in inflammatory bowel disease. Inflammatory Bowel Diseases. 12: 524-34. PMID 16775498 DOI: 10.1097/00054725-200606000-00013  0.43
2006 Carey R, Han X, Bonkowski E, Denson L. GENE EXPRESSION PROFILES DEFINE SUBTYPES OF PEDIATRIC CROHN'S COLITIS AT DIAGNOSIS Journal of Pediatric Gastroenterology and Nutrition. 43: E55. DOI: 10.1097/00005176-200610000-00161  0.322
2006 Tomer G, Wetzler G, Keddache M, Ceballos C, Denson LA. THE ROLE OF OCTN1/2 GENES IN ASHKENAZI JEWISH CHILDREN WITH CROHN'S DISEASE Journal of Pediatric Gastroenterology and Nutrition. 43: E53. DOI: 10.1097/00005176-200610000-00153  0.367
2005 Han X, Sosnowska D, Bonkowski EL, Denson LA. Growth hormone inhibits signal transducer and activator of transcription 3 activation and reduces disease activity in murine colitis. Gastroenterology. 129: 185-203. PMID 16012947 DOI: 10.1053/J.Gastro.2005.05.018  0.379
2003 Bohan A, Chen WS, Denson LA, Held MA, Boyer JL. Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis. The Journal of Biological Chemistry. 278: 36688-98. PMID 12837754 DOI: 10.1074/Jbc.M304011200  0.302
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