James K. Foskett - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
General Biophysics, Physiology Biology

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Foskett JK. Structures of CALHM channels revealed. Nature Structural & Molecular Biology. 27: 227-228. PMID 32086497 DOI: 10.1038/s41594-020-0391-y  0.4
2018 Ma Z, Taruno A, Ohmoto M, Jyotaki M, Lim JC, Miyazaki H, Niisato N, Marunaka Y, Lee RJ, Hoff H, Payne R, Demuro A, Parker I, Mitchell CH, Henao-Mejia J, ... ... Foskett JK, et al. CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes. Neuron. PMID 29681531 DOI: 10.1016/J.Neuron.2018.03.043  0.765
2018 Payne R, Hoff H, Roskowski A, Foskett JK. MICU2 Restricts Spatial Crosstalk between InsP3R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU Biophysical Journal. 114: 119a-120a. DOI: 10.1016/j.bpj.2017.11.684  0.334
2017 Payne R, Hoff H, Roskowski A, Foskett JK. MICU2 Restricts Spatial Crosstalk between InsP3R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU. Cell Reports. 21: 3141-3154. PMID 29241542 DOI: 10.1016/j.celrep.2017.11.064  0.334
2017 Tanis JE, Ma Z, Foskett JK. The N-terminus regulates voltage-dependent gating of CALHM ion channels. American Journal of Physiology. Cell Physiology. ajpcell.00318.2016. PMID 28515089 DOI: 10.1152/Ajpcell.00318.2016  0.533
2017 Ma Z, Saung WT, Foskett JK. Action Potentials and Ion Conductances in Wild-type and CALHM1-knockout Type II Taste Cells. Journal of Neurophysiology. jn.00835.2016. PMID 28202574 DOI: 10.1152/jn.00835.2016  0.328
2017 Vais H, Foskett JK, Daniel Mak D. Novel Luminal Regulation of Inositol 1,4,5-Trisphosphate Receptor Channel Gating Biophysical Journal. 112: 232a-233a. DOI: 10.1016/j.bpj.2016.11.1276  0.408
2016 Yang J, Vais H, Gu W, Foskett JK. Biphasic regulation of InsP3 receptor gating by dual Ca2+ release channel BH3-like domains mediates Bcl-xL control of cell viability. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976600 DOI: 10.1073/pnas.1517935113  0.534
2016 Vais H, Mallilankaraman K, Mak DD, Hoff H, Payne R, Tanis JE, Foskett JK. EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter. Cell Reports. PMID 26774479 DOI: 10.1016/J.Celrep.2015.12.054  0.479
2015 Ma Z, Tanis JE, Taruno A, Foskett JK. Calcium homeostasis modulator (CALHM) ion channels. Pflugers Archiv : European Journal of Physiology. PMID 26603282 DOI: 10.1007/S00424-015-1757-6  0.828
2015 Vais H, Tanis JE, Müller M, Payne R, Mallilankaraman K, Foskett JK. MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter. Cell Metabolism. 22: 533-5. PMID 26445506 DOI: 10.1016/J.Cmet.2015.09.015  0.444
2015 Mak DO, Cheung KH, Toglia P, Foskett JK, Ullah G. Analyzing and Quantifying the Gain-of-Function Enhancement of IP3 Receptor Gating by Familial Alzheimer's Disease-Causing Mutants in Presenilins. Plos Computational Biology. 11: e1004529. PMID 26439382 DOI: 10.1371/Journal.Pcbi.1004529  0.479
2015 Mak DO, Foskett JK. Inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum: A single-channel point of view. Cell Calcium. 58: 67-78. PMID 25555684 DOI: 10.1016/j.ceca.2014.12.008  0.582
2014 Vingtdeux V, Tanis JE, Chandakkar P, Zhao H, Dreses-Werringloer U, Campagne F, Foskett JK, Marambaud P. Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels. Plos One. 9: e112484. PMID 25386646 DOI: 10.1371/Journal.Pone.0112484  0.39
2014 Doonan PJ, Chandramoorthy HC, Hoffman NE, Zhang X, Cárdenas C, Shanmughapriya S, Rajan S, Vallem S, Chen X, Foskett JK, Cheung JY, Houser SR, Madesh M. LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4936-49. PMID 25077561 DOI: 10.1096/Fj.14-256453  0.345
2014 Joseph JD, Peng Y, Mak DO, Cheung KH, Vais H, Foskett JK, Wei H. General anesthetic isoflurane modulates inositol 1,4,5-trisphosphate receptor calcium channel opening. Anesthesiology. 121: 528-37. PMID 24878495 DOI: 10.1097/ALN.0000000000000316  0.529
2014 Shilling D, Müller M, Takano H, Mak DO, Abel T, Coulter DA, Foskett JK. Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6910-23. PMID 24828645 DOI: 10.1523/Jneurosci.5441-13.2014  0.317
2014 Lee RJ, Foskett JK. Ca²⁺ signaling and fluid secretion by secretory cells of the airway epithelium. Cell Calcium. 55: 325-36. PMID 24703093 DOI: 10.1016/j.ceca.2014.02.001  0.492
2014 Foskett JK, Ma Z, Siebert AP, Lamitina T, Marambaud P, Tanis JE, Taruno A. Calcium Homeostasis Modulator (CALHM) Ion Channels: Structure, Functions and Physiological Roles Membrane. 39: 41-47. DOI: 10.5360/membrane.39.41  0.758
2014 Tanis J, Ma Z, Foskett JK. Characterization of the Intrinsic Voltage-Dependent Gating Mechanism of CALHM Ion Channels Biophysical Journal. 106: 752a. DOI: 10.1016/J.Bpj.2013.11.4141  0.595
2013 Taruno A, Matsumoto I, Ma Z, Marambaud P, Foskett JK. How do taste cells lacking synapses mediate neurotransmission? CALHM1, a voltage-gated ATP channel. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 1111-8. PMID 24105910 DOI: 10.1002/Bies.201300077  0.733
2013 Mak DO, Vais H, Cheung KH, Foskett JK. Isolating nuclei from cultured cells for patch-clamp electrophysiology of intracellular Ca(2+) channels. Cold Spring Harbor Protocols. 2013: 880-4. PMID 24003193 DOI: 10.1101/pdb.prot073056  0.325
2013 Mak DO, Vais H, Cheung KH, Foskett JK. Patch-clamp electrophysiology of intracellular Ca2+ channels. Cold Spring Harbor Protocols. 2013: 787-97. PMID 24003191 DOI: 10.1101/pdb.top066217  0.605
2013 Tanis JE, Ma Z, Krajacic P, He L, Foskett JK, Lamitina T. CLHM-1 is a functionally conserved and conditionally toxic Ca2+-permeable ion channel in Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12275-86. PMID 23884934 DOI: 10.1523/JNEUROSCI.5919-12.2013  0.537
2013 Taruno A, Vingtdeux V, Ohmoto M, Ma Z, Dvoryanchikov G, Li A, Adrien L, Zhao H, Leung S, Abernethy M, Koppel J, Davies P, Civan MM, Chaudhari N, Matsumoto I, ... ... Foskett JK, et al. CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature. 495: 223-6. PMID 23467090 DOI: 10.1038/Nature11906  0.748
2013 Siebert AP, Ma Z, Grevet JD, Demuro A, Parker I, Foskett JK. Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins. The Journal of Biological Chemistry. 288: 6140-53. PMID 23300080 DOI: 10.1074/Jbc.M112.409789  0.798
2013 Daniel Mak D, Vais H, White C, Foskett JK. Cytoplasmic [InsP3] Drop Induces Transient High-Open-Probability Gating Mode in Type 1 InsP3R Channel Biophysical Journal. 104: 121a-122a. DOI: 10.1016/j.bpj.2012.11.701  0.375
2013 Shilling D, Muller M, Takano H, Mak DD, Abel T, Coulter D, Foskett JK. Exaggerated [Ca2+]I Signaling and Alzheimer's Disease-Like Phenotypes of PS1M146V Mice are Attenuated by Decreasing Brain InsP3R-1 Protein Levels Biophysical Journal. 104: 121a. DOI: 10.1016/J.Bpj.2012.11.698  0.424
2013 Taruno A, Li A, Ma Z, Marambaud P, Ohmoto M, Matsumoto I, Civan MM, Tordoff MG, Foskett JK. CALHM1 Ion Channel Mediates Purinergic Neurotransmission from Taste Buds to Gustatory Nerve Terminals during Sweet and Bitter Perception Biophysical Journal. 104: 631a. DOI: 10.1016/J.Bpj.2012.11.3489  0.702
2013 Ma Z, Taruno A, Siebert AP, Li A, Civan MM, Foskett JK. CALHM1 is an Extracellular Ca2+- and Voltage-Gated ATP Permeable Ion Channel Biophysical Journal. 104: 631a. DOI: 10.1016/J.Bpj.2012.11.3488  0.805
2013 Mallilankaraman K, Doonan P, Cárdenas C, Foskett JK, Madesh M. A Regulatory Complex of the Mitochondrial Uniporter Ca2+ Channel Biophysical Journal. 104: 7a. DOI: 10.1016/J.Bpj.2012.11.064  0.465
2012 Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, ... Foskett JK, et al. MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism. Nature Cell Biology. 14: 1336-43. PMID 23178883 DOI: 10.1038/ncb2622  0.453
2012 Vais H, Foskett JK, Ullah G, Pearson JE, Mak DO. Permeant calcium ion feed-through regulation of single inositol 1,4,5-trisphosphate receptor channel gating. The Journal of General Physiology. 140: 697-716. PMID 23148262 DOI: 10.1085/Jgp.201210804  0.564
2012 Mallilankaraman K, Doonan P, Cárdenas C, Chandramoorthy HC, Müller M, Miller R, Hoffman NE, Gandhirajan RK, Molgó J, Birnbaum MJ, Rothberg BS, Mak DO, Foskett JK, Madesh M. MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival. Cell. 151: 630-44. PMID 23101630 DOI: 10.1016/J.Cell.2012.10.011  0.422
2012 Lee RJ, Foskett JK. Why mouse airway submucosal gland serous cells do not secrete fluid in response to cAMP stimulation. The Journal of Biological Chemistry. 287: 38316-26. PMID 22989883 DOI: 10.1074/jbc.M112.412817  0.334
2012 Kopil CM, Siebert AP, Foskett JK, Neumar RW. Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor impairs ER Ca(2+) buffering and causes neurodegeneration in primary cortical neurons. Journal of Neurochemistry. 123: 147-58. PMID 22762283 DOI: 10.1111/J.1471-4159.2012.07859.X  0.787
2012 Ma Z, Siebert AP, Cheung KH, Lee RJ, Johnson B, Cohen AS, Vingtdeux V, Marambaud P, Foskett JK. Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability. Proceedings of the National Academy of Sciences of the United States of America. 109: E1963-71. PMID 22711817 DOI: 10.1073/Pnas.1204023109  0.817
2012 Cárdenas C, Foskett JK. Mitochondrial Ca(2+) signals in autophagy. Cell Calcium. 52: 44-51. PMID 22459281 DOI: 10.1016/j.ceca.2012.03.001  0.394
2012 Shilling D, Mak DO, Kang DE, Foskett JK. Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels. The Journal of Biological Chemistry. 287: 10933-44. PMID 22311977 DOI: 10.1074/Jbc.M111.300491  0.506
2012 Vais H, Foskett JK, Daniel Mak D. Calcium-Flux-Mediated Modulation of InsP3R Channel Activity by ER Luminal Calcium Concentration Biophysical Journal. 102: 110a. DOI: 10.1016/j.bpj.2011.11.621  0.327
2011 Vais H, Foskett JK, Mak DO. InsP3R channel gating altered by clustering? Nature. 478: E1-2; discussion E2-. PMID 21993761 DOI: 10.1038/nature10493  0.324
2011 Kopil CM, Vais H, Cheung KH, Siebert AP, Mak DO, Foskett JK, Neumar RW. Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor (InsP(3)R1) has InsP(3)-independent gating and disrupts intracellular Ca(2+) homeostasis. The Journal of Biological Chemistry. 286: 35998-6010. PMID 21859719 DOI: 10.1074/Jbc.M111.254177  0.814
2011 Müller M, Cárdenas C, Mei L, Cheung KH, Foskett JK. Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling. Proceedings of the National Academy of Sciences of the United States of America. 108: 13293-8. PMID 21784978 DOI: 10.1073/pnas.1109297108  0.377
2011 Müller M, Cheung KH, Foskett JK. Enhanced ROS generation mediated by Alzheimer's disease presenilin regulation of InsP3R Ca2+ signaling. Antioxidants & Redox Signaling. 14: 1225-35. PMID 20701429 DOI: 10.1089/ars.2010.3421  0.427
2011 Siebert AP, Ma Z, Foskett JK. Permeation Properties of CALHM1 Biophysical Journal. 100: 94a. DOI: 10.1016/J.Bpj.2010.12.717  0.771
2011 Tanis J, Ma Z, Krajacic P, He L, Foskett J, Lamitina T. C. Elegans CLHM-1 expression Induces an Evolutionarily Conserved Voltage- and Ca2+-Dependent Ca2+ Permeability Biophysical Journal. 100: 93a. DOI: 10.1016/J.Bpj.2010.12.713  0.474
2011 Ma Z, Siebert AP, Foskett JK. A novel Calcium Channel Induced by CALHM1 Expression Detects Levels of Extracellular Calcium Biophysical Journal. 100: 259a. DOI: 10.1016/J.Bpj.2010.12.1630  0.819
2011 Vais H, Foskett JK, Mak DD. IP3 Receptor Channels are Clustered Before IP3 Exposure with No Discernible Effect on Single-Channel Gating Properties Biophysical Journal. 100: 251a. DOI: 10.1016/j.bpj.2010.12.1587  0.375
2011 Vais H, Foskett JK, Mak DD. Unitary Calcium Current Through Recombinant Mammalian Type 3 IP3 Receptor Channels Under Physiological Ionic Conditions Biophysical Journal. 100: 251a. DOI: 10.1016/j.bpj.2010.12.1586  0.387
2010 Foskett JK, Daniel Mak DO. Regulation of IP(3)R Channel Gating by Ca(2+) and Ca(2+) Binding Proteins. Current Topics in Membranes. 66: 235-72. PMID 22353483 DOI: 10.1016/S1063-5823(10)66011-5  0.512
2010 Vais H, Foskett JK, Mak DO. Unitary Ca(2+) current through recombinant type 3 InsP(3) receptor channels under physiological ionic conditions. The Journal of General Physiology. 136: 687-700. PMID 21078871 DOI: 10.1085/jgp.201010513  0.564
2010 Lee RJ, Foskett JK. cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways. The Journal of Clinical Investigation. 120: 3137-48. PMID 20739756 DOI: 10.1172/JCI42992  0.325
2010 Schwarzer C, Wong S, Shi J, Matthes E, Illek B, Ianowski JP, Arant RJ, Isacoff E, Vais H, Foskett JK, Maiellaro I, Hofer AM, Machen TE. Pseudomonas aeruginosa Homoserine lactone activates store-operated cAMP and cystic fibrosis transmembrane regulator-dependent Cl- secretion by human airway epithelia. The Journal of Biological Chemistry. 285: 34850-63. PMID 20739289 DOI: 10.1074/Jbc.M110.167668  0.346
2010 Cárdenas C, Miller RA, Smith I, Bui T, Molgó J, Müller M, Vais H, Cheung KH, Yang J, Parker I, Thompson CB, Birnbaum MJ, Hallows KR, Foskett JK. Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. Cell. 142: 270-83. PMID 20655468 DOI: 10.1016/J.Cell.2010.06.007  0.366
2010 Vais H, Siebert AP, Ma Z, Fernández-Mongil M, Foskett JK, Mak DO. Redox-regulated heterogeneous thresholds for ligand recruitment among InsP3R Ca2+-release channels. Biophysical Journal. 99: 407-16. PMID 20643058 DOI: 10.1016/J.Bpj.2010.04.034  0.819
2010 Cárdenas C, Escobar M, García A, Osorio-Reich M, Härtel S, Foskett JK, Franzini-Armstrong C. Visualization of inositol 1,4,5-trisphosphate receptors on the nuclear envelope outer membrane by freeze-drying and rotary shadowing for electron microscopy. Journal of Structural Biology. 171: 372-81. PMID 20457258 DOI: 10.1016/j.jsb.2010.05.003  0.388
2010 Foskett JK. Inositol trisphosphate receptor Ca2+ release channels in neurological diseases. PflüGers Archiv : European Journal of Physiology. 460: 481-94. PMID 20383523 DOI: 10.1007/s00424-010-0826-0  0.43
2010 Cheung KH, Mei L, Mak DO, Hayashi I, Iwatsubo T, Kang DE, Foskett JK. Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons. Science Signaling. 3: ra22. PMID 20332427 DOI: 10.1126/Scisignal.2000818  0.418
2010 Eckenrode EF, Yang J, Velmurugan GV, Foskett JK, White C. Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dependent Ca2+ signaling. The Journal of Biological Chemistry. 285: 13678-84. PMID 20189983 DOI: 10.1074/jbc.M109.096040  0.354
2010 Lee RJ, Foskett JK. Mechanisms of Ca2+-stimulated fluid secretion by porcine bronchial submucosal gland serous acinar cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L210-31. PMID 19965983 DOI: 10.1152/ajplung.00342.2009  0.435
2010 Ma Z, Siebert AP, Grevet JD, Foskett JK. Biophysical Properties of Calcium Homeostasis Modulator 1 (CALHM1) Ion Channel Biophysical Journal. 98: 22a. DOI: 10.1016/J.Bpj.2009.12.134  0.821
2010 Foskett JK. Alzheimer's Presenilin Regulation of InsP3R Ca2+ Release Channel Gating Biophysical Journal. 98: 3a. DOI: 10.1016/j.bpj.2009.12.016  0.562
2009 Foskett JK, Yang J, Cheung K, Vais H. Bcl-xL Regulation of InsP3 Receptor Gating Mediated by Dual Ca2+ Release Channel BH3 Domains Biophysical Journal. 96: 391a. DOI: 10.1016/j.bpj.2008.12.2917  0.525
2008 Lee RJ, Harlow JM, Limberis MP, Wilson JM, Foskett JK. HCO3(-) secretion by murine nasal submucosal gland serous acinar cells during Ca2+-stimulated fluid secretion. The Journal of General Physiology. 132: 161-83. PMID 18591422 DOI: 10.1085/Jgp.200810017  0.365
2008 Dreses-Werringloer U, Lambert JC, Vingtdeux V, Zhao H, Vais H, Siebert A, Jain A, Koppel J, Rovelet-Lecrux A, Hannequin D, Pasquier F, Galimberti D, Scarpini E, Mann D, Lendon C, ... ... Foskett JK, et al. A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell. 133: 1149-61. PMID 18585350 DOI: 10.1016/J.Cell.2008.05.048  0.747
2008 Cheung KH, Shineman D, Müller M, Cárdenas C, Mei L, Yang J, Tomita T, Iwatsubo T, Lee VM, Foskett JK. Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating. Neuron. 58: 871-83. PMID 18579078 DOI: 10.1016/J.Neuron.2008.04.015  0.507
2007 Ionescu L, White C, Cheung KH, Shuai J, Parker I, Pearson JE, Foskett JK, Mak DO. Mode switching is the major mechanism of ligand regulation of InsP3 receptor calcium release channels. The Journal of General Physiology. 130: 631-45. PMID 17998395 DOI: 10.1085/Jgp.200709859  0.505
2007 Mak DO, Pearson JE, Loong KP, Datta S, Fernández-Mongil M, Foskett JK. Rapid ligand-regulated gating kinetics of single inositol 1,4,5-trisphosphate receptor Ca2+ release channels. Embo Reports. 8: 1044-51. PMID 17932510 DOI: 10.1038/sj.embor.7401087  0.594
2007 Jones RG, Bui T, White C, Madesh M, Krawczyk CM, Lindsten T, Hawkins BJ, Kubek S, Frauwirth KA, Wang YL, Conway SJ, Roderick HL, Bootman MD, Shen H, Foskett JK, et al. The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis. Immunity. 27: 268-80. PMID 17692540 DOI: 10.1016/J.Immuni.2007.05.023  0.348
2007 Li C, Wang X, Vais H, Thompson CB, Foskett JK, White C. Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating. Proceedings of the National Academy of Sciences of the United States of America. 104: 12565-70. PMID 17636122 DOI: 10.1073/Pnas.0702489104  0.429
2007 Shuai J, Pearson JE, Foskett JK, Mak DO, Parker I. A kinetic model of single and clustered IP3 receptors in the absence of Ca2+ feedback. Biophysical Journal. 93: 1151-62. PMID 17526578 DOI: 10.1529/Biophysj.107.108795  0.532
2007 Lee RJ, Limberis MP, Hennessy MF, Wilson JM, Foskett JK. Optical imaging of Ca2+-evoked fluid secretion by murine nasal submucosal gland serous acinar cells. The Journal of Physiology. 582: 1099-124. PMID 17525116 DOI: 10.1113/Jphysiol.2007.131995  0.352
2007 Foskett JK, White C, Cheung KH, Mak DO. Inositol trisphosphate receptor Ca2+ release channels. Physiological Reviews. 87: 593-658. PMID 17429043 DOI: 10.1152/physrev.00035.2006  0.594
2006 van Rossum DB, Patterson RL, Cheung KH, Barrow RK, Syrovatkina V, Gessell GS, Burkholder SG, Watkins DN, Foskett JK, Snyder SH. DANGER, a novel regulatory protein of inositol 1,4,5-trisphosphate-receptor activity. The Journal of Biological Chemistry. 281: 37111-6. PMID 16990268 DOI: 10.1074/Jbc.M608760200  0.331
2006 White C, Yang J, Monteiro MJ, Foskett JK. CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel. The Journal of Biological Chemistry. 281: 20825-33. PMID 16723353 DOI: 10.1074/jbc.M602175200  0.43
2006 Ionescu L, Cheung KH, Vais H, Mak DO, White C, Foskett JK. Graded recruitment and inactivation of single InsP3 receptor Ca2+-release channels: implications for quantal [corrected] Ca2+release. The Journal of Physiology. 573: 645-62. PMID 16644799 DOI: 10.1113/jphysiol.2006.109504  0.592
2005 White C, Li C, Yang J, Petrenko NB, Madesh M, Thompson CB, Foskett JK. The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R. Nature Cell Biology. 7: 1021-8. PMID 16179951 DOI: 10.1038/Ncb1302  0.404
2005 Kinoshita-Kawada M, Tang J, Xiao R, Kaneko S, Foskett JK, Zhu MX. Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes. PflüGers Archiv : European Journal of Physiology. 450: 345-54. PMID 15895247 DOI: 10.1007/S00424-005-1419-1  0.532
2005 Ferreri-Jacobia M, Mak DO, Foskett JK. Translational mobility of the type 3 inositol 1,4,5-trisphosphate receptor Ca2+ release channel in endoplasmic reticulum membrane. The Journal of Biological Chemistry. 280: 3824-31. PMID 15537642 DOI: 10.1074/jbc.M409462200  0.541
2004 Foskett JK, Mak DO. Novel model of calcium and inositol 1,4,5-trisphosphate regulation of InsP3 receptor channel gating in native endoplasmic reticulum. Biological Research. 37: 513-9. PMID 15709677  0.552
2004 Yoo D, Flagg TP, Olsen O, Raghuram V, Foskett JK, Welling PA. Assembly and trafficking of a multiprotein ROMK (Kir 1.1) channel complex by PDZ interactions. The Journal of Biological Chemistry. 279: 6863-73. PMID 14604981 DOI: 10.1074/Jbc.M311599200  0.313
2003 Mak DO, McBride SM, Foskett JK. Spontaneous channel activity of the inositol 1,4,5-trisphosphate (InsP3) receptor (InsP3R). Application of allosteric modeling to calcium and InsP3 regulation of InsP3R single-channel gating. The Journal of General Physiology. 122: 583-603. PMID 14581584 DOI: 10.1085/jgp.200308809  0.576
2003 Mak DO, McBride SM, Petrenko NB, Foskett JK. Novel regulation of calcium inhibition of the inositol 1,4,5-trisphosphate receptor calcium-release channel. The Journal of General Physiology. 122: 569-81. PMID 14581583 DOI: 10.1085/jgp.200308808  0.555
2003 Raghuram V, Hormuth H, Foskett JK. A kinase-regulated mechanism controls CFTR channel gating by disrupting bivalent PDZ domain interactions. Proceedings of the National Academy of Sciences of the United States of America. 100: 9620-5. PMID 12881487 DOI: 10.1073/pnas.1633250100  0.395
2003 Zeng W, Mak DO, Li Q, Shin DM, Foskett JK, Muallem S. A new mode of Ca2+ signaling by G protein-coupled receptors: gating of IP3 receptor Ca2+ release channels by Gbetagamma. Current Biology : Cb. 13: 872-6. PMID 12747838 DOI: 10.1016/S0960-9822(03)00330-0  0.434
2003 Hallows KR, McCane JE, Kemp BE, Witters LA, Foskett JK. Regulation of channel gating by AMP-activated protein kinase modulates cystic fibrosis transmembrane conductance regulator activity in lung submucosal cells. The Journal of Biological Chemistry. 278: 998-1004. PMID 12427743 DOI: 10.1074/jbc.M210621200  0.354
2003 Zeng W, Mak DOD, Li Q, Shin DM, Foskett JK, Muallem S. A new mode of Ca2+ signaling by G protein-coupled receptors: Gating of IP3 receptor Ca2+ release channels by Gβγ Current Biology. 13: 872-876. DOI: 10.1016/S0960-9822(03)00330-0  0.453
2002 Ben-Chetrit A, Antenos M, Jurisicova A, Pasyk EA, Chitayat D, Foskett JK, Casper RF. Expression of cystic fibrosis transmembrane conductance regulator during early human embryo development. Molecular Human Reproduction. 8: 758-64. PMID 12149408  0.306
2002 Yang J, McBride S, Mak DO, Vardi N, Palczewski K, Haeseleer F, Foskett JK. Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels. Proceedings of the National Academy of Sciences of the United States of America. 99: 7711-6. PMID 12032348 DOI: 10.1073/Pnas.102006299  0.535
2001 Boehning D, Joseph SK, Mak DO, Foskett JK. Single-channel recordings of recombinant inositol trisphosphate receptors in mammalian nuclear envelope. Biophysical Journal. 81: 117-24. PMID 11423400 DOI: 10.1016/S0006-3495(01)75685-8  0.549
2001 Mak DO, McBride S, Foskett JK. ATP regulation of recombinant type 3 inositol 1,4,5-trisphosphate receptor gating. The Journal of General Physiology. 117: 447-56. PMID 11331355 DOI: 10.1085/jgp.117.5.447  0.598
2001 Mak DO, McBride S, Foskett JK. Regulation by Ca2+ and inositol 1,4,5-trisphosphate (InsP3) of single recombinant type 3 InsP3 receptor channels. Ca2+ activation uniquely distinguishes types 1 and 3 insp3 receptors. The Journal of General Physiology. 117: 435-46. PMID 11331354 DOI: 10.1085/jgp.117.5.435  0.557
2001 Mak DO, McBride S, Foskett JK. ATP-dependent adenophostin activation of inositol 1,4,5-trisphosphate receptor channel gating: kinetic implications for the durations of calcium puffs in cells. The Journal of General Physiology. 117: 299-314. PMID 11279251 DOI: 10.1085/jgp.117.4.299  0.544
2001 Boehning D, Mak DO, Foskett JK, Joseph SK. Molecular determinants of ion permeation and selectivity in inositol 1,4,5-trisphosphate receptor Ca2+ channels. The Journal of Biological Chemistry. 276: 13509-12. PMID 11278266 DOI: 10.1074/jbc.C100094200  0.588
2001 Raghuram V, Mak DO, Foskett JK. Regulation of cystic fibrosis transmembrane conductance regulator single-channel gating by bivalent PDZ-domain-mediated interaction. Proceedings of the National Academy of Sciences of the United States of America. 98: 1300-5. PMID 11158634 DOI: 10.1073/pnas.031538898  0.363
2000 Jiang Q, Li J, Dubroff R, Ahn YJ, Foskett JK, Engelhardt J, Kleyman TR. Epithelial sodium channels regulate cystic fibrosis transmembrane conductance regulator chloride channels in Xenopus oocytes. The Journal of Biological Chemistry. 275: 13266-74. PMID 10788432 DOI: 10.1074/Jbc.275.18.13266  0.423
2000 Mak DO, McBride S, Raghuram V, Yue Y, Joseph SK, Foskett JK. Single-channel properties in endoplasmic reticulum membrane of recombinant type 3 inositol trisphosphate receptor. The Journal of General Physiology. 115: 241-56. PMID 10694253 DOI: 10.1085/jgp.115.3.241  0.53
1999 Mak DO, McBride S, Foskett JK. ATP regulation of type 1 inositol 1,4,5-trisphosphate receptor channel gating by allosteric tuning of Ca(2+) activation. The Journal of Biological Chemistry. 274: 22231-7. PMID 10428789 DOI: 10.1074/jbc.274.32.22231  0.559
1998 Mak DO, McBride S, Foskett JK. Inositol 1,4,5-trisphosphate [correction of tris-phosphate] activation of inositol trisphosphate [correction of tris-phosphate] receptor Ca2+ channel by ligand tuning of Ca2+ inhibition. Proceedings of the National Academy of Sciences of the United States of America. 95: 15821-5. PMID 9861054 DOI: 10.1073/pnas.95.26.15821  0.474
1998 Jiang Q, Mak D, Devidas S, Schwiebert EM, Bragin A, Zhang Y, Skach WR, Guggino WB, Foskett JK, Engelhardt JF. Cystic fibrosis transmembrane conductance regulator-associated ATP release is controlled by a chloride sensor. The Journal of Cell Biology. 143: 645-57. PMID 9813087 DOI: 10.1083/Jcb.143.3.645  0.342
1998 Mak DO, Foskett JK. Effects of divalent cations on single-channel conduction properties of Xenopus IP3 receptor. The American Journal of Physiology. 275: C179-88. PMID 9688849  0.374
1998 Kosari F, Sheng S, Li J, Mak DO, Foskett JK, Kleyman TR. Subunit stoichiometry of the epithelial sodium channel. The Journal of Biological Chemistry. 273: 13469-74. PMID 9593680 DOI: 10.1074/jbc.273.22.13469  0.45
1998 Foskett JK. ClC and CFTR chloride channel gating. Annual Review of Physiology. 60: 689-717. PMID 9558482 DOI: 10.1146/annurev.physiol.60.1.689  0.432
1998 Sugita M, Yue Y, Foskett JK. CFTR Cl- channel and CFTR-associated ATP channel: distinct pores regulated by common gates. The Embo Journal. 17: 898-908. PMID 9463368 DOI: 10.1093/emboj/17.4.898  0.437
1997 Mak DO, Foskett JK. Single-channel kinetics, inactivation, and spatial distribution of inositol trisphosphate (IP3) receptors in Xenopus oocyte nucleus. The Journal of General Physiology. 109: 571-87. PMID 9154905 DOI: 10.1085/jgp.109.5.571  0.517
1997 Pasyk EA, Foskett JK. Cystic fibrosis transmembrane conductance regulator-associated ATP and adenosine 3'-phosphate 5'-phosphosulfate channels in endoplasmic reticulum and plasma membranes. The Journal of Biological Chemistry. 272: 7746-51. PMID 9065435  0.35
1995 Pasyk EA, Foskett JK. Mutant (delta F508) cystic fibrosis transmembrane conductance regulator Cl- channel is functional when retained in endoplasmic reticulum of mammalian cells. The Journal of Biological Chemistry. 270: 12347-50. PMID 7539001 DOI: 10.1074/jbc.270.21.12347  0.357
1994 Foskett JK, Wong MM, Sue-A-Quan G, Robertson MA. Isosmotic modulation of cell volume and intracellular ion activities during stimulation of single exocrine cells Journal of Experimental Zoology. 268: 104-110. PMID 8301250  0.393
1994 Gaisano HY, Wong D, Sheu L, Foskett JK. Calcium release by cholecystokinin analogue OPE is IP3 dependent in single rat pancreatic acinar cells American Journal of Physiology - Cell Physiology. 267. PMID 8048482 DOI: 10.1152/Ajpcell.1994.267.1.C220  0.431
1994 Robertson MA, Foskett JK. Na+ transport pathways in secretory acinar cells: Membrane cross talk mediated by [Cl-](i) American Journal of Physiology - Cell Physiology. 267. PMID 8048476  0.363
1994 Foskett JK, Wong DC. [Ca2+]i inhibition of Ca2+ release-activated Ca2+ influx underlies agonist- and thapsigargin-induced [Ca2+]i oscillations in salivary acinar cells. The Journal of Biological Chemistry. 269: 31525-32. PMID 7989320  0.433
1994 Gaisano HY, Miller LJ, Foskett JK. Suppression of Ca2+ oscillations induced by cholecystokinin (CCK) and its analog OPE in rat pancreatic acinar cells by low-level protein kinase C activation without transition of the CCK receptor from a high- to low-affinity state PflüGers Archiv European Journal of Physiology. 427: 455-462. PMID 7971144 DOI: 10.1007/Bf00374261  0.386
1994 Mak DOD, Foskett JK. Single-channel inositol 1,4,5-trisphosphate receptor currents revealed by patch clamp of isolated Xenopus oocyte nuclei Journal of Biological Chemistry. 269: 29375-29378. PMID 7961913  0.526
1994 Robertson MA, Foskett JK. Membrane crosstalk in secretory epithelial cells mediated by intracellular chloride concentration Japanese Journal of Physiology. 44. PMID 7752548  0.364
1994 Tohda H, Foskett JK, O'Brodovich H, Marunaka Y. Cl- regulation of a Ca(2+)-activated nonselective cation channel in beta-agonist-treated fetal distal lung epithelium. The American Journal of Physiology. 266: C104-9. PMID 7508184 DOI: 10.1152/Ajpcell.1994.266.1.C104  0.457
1994 Tohda H, Foskett JK, O'Brodovich H, Marunaka Y. Cl- regulation of a Ca2+-activated nonselective cation channel in beta-agonist-treated fetal distal lung epithelium Am.J.Physiol.. 266: C104-C109.  0.42
1993 Dho S, Foskett JK. Optical imaging of Cl- permeabilities in normal and CFTR-expressing mouse L cells. Biochimica Et Biophysica Acta. 1152: 83-90. PMID 7691179 DOI: 10.1016/0005-2736(93)90234-Q  0.344
1992 Foskett JK, Wong D. Calcium oscillations in parotid acinar cells induced by microsomal Ca2+- ATPase inhibition American Journal of Physiology - Cell Physiology. 262. PMID 1532294  0.423
1991 Foskett JK, Roifman CM, Wong D. Activation of calcium oscillations by thapsigargin in parotid acinar cells Journal of Biological Chemistry. 266: 2778-2782. PMID 1847134  0.438
1991 Foskett JK, Wong D. Free cytoplasmic Ca2+ concentration oscillations in thapsigargin-treated parotid acinar cells are caffeine- and ryanodine-sensitive Journal of Biological Chemistry. 266: 14535-14538. PMID 1830587  0.405
1989 Foskett JK, Melvin JE. Activation of salivary secretion: Coupling of cell volume and [Ca2+](i) in single cells Science. 244: 1582-1585. PMID 2500708  0.42
1989 Foskett JK, Gunter-Smith PJ, Melvin JE, Turner RJ. Physiological localization of an agonist-sensitive pool of Ca2+ in parotid acinar cells Proceedings of the National Academy of Sciences of the United States of America. 86: 167-171. PMID 2492098  0.456
1984 Foskett JK, Spring KR. Ca and microfilaments in epithelial cell volume regulation Federation Proceedings. 43: no. 949.  0.377
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