Zhong Zuo - Publications

Affiliations: 
The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Pharmacy, Biochemistry

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhang J, Wang D, Zou L, Xiao M, Zhang Y, Li Z, Yang L, Ge G, Zuo Z. Rapid bioluminescence assay for monitoring rat CES1 activity and its alteration by traditional Chinese medicines. Journal of Pharmaceutical Analysis. 10: 253-262. PMID 32612872 DOI: 10.1016/J.Jpha.2020.05.006  0.351
2019 Li Y, Meng Q, Yang M, Liu D, Hou X, Tang L, Wang X, Lyu Y, Chen X, Liu K, Yu AM, Zuo Z, Bi H. Current trends in drug metabolism and pharmacokinetics. Acta Pharmaceutica Sinica. B. 9: 1113-1144. PMID 31867160 DOI: 10.1016/J.Apsb.2019.10.001  0.325
2019 Wang Q, Ren T, Zhao J, Wong CH, Chan HYE, Zuo Z. Exclusion of unsuitable CNS drug candidates based on their physicochemical properties and unbound fractions in biomatrices for brain microdialysis investigations. Journal of Pharmaceutical and Biomedical Analysis. 112946. PMID 31727358 DOI: 10.1016/J.Jpba.2019.112946  0.316
2019 Ren T, Zuo Z. Role of piperine in CNS diseases: pharmacodynamics, pharmacokinetics and drug interactions. Expert Opinion On Drug Metabolism & Toxicology. PMID 31566028 DOI: 10.1080/17425255.2019.1672658  0.336
2019 Lyu Y, Zhang Y, Yang M, Lin L, Yang X, Cheung SCK, Shaw PC, Chan PKS, Kong APS, Zuo Z. Pharmacokinetic interactions between metformin and berberine in rats: Role of oral administration sequences and microbiota. Life Sciences. 116818. PMID 31473193 DOI: 10.1016/J.Lfs.2019.116818  0.305
2019 Yang M, Tse AHW, Lee A, Joynt GM, Zuo Z. Large inter-individual variability in pharmacokinetics of dexmedetomidine and its two major N-glucuronides in adult intensive care unit patients. Journal of Pharmaceutical and Biomedical Analysis. 175: 112777. PMID 31362246 DOI: 10.1016/J.Jpba.2019.07.025  0.304
2019 Ren T, Xiao M, Yang M, Zhao J, Zhang Y, Hu M, Cheng Y, Xu H, Zhang C, Yan X, Zuo Z. Reduced Systemic and Brain Exposure with Inhibited Liver Metabolism of Carbamazepine After Its Long-Term Combination Treatment with Piperine for Epilepsy Control in Rats. The Aaps Journal. 21: 90. PMID 31321577 DOI: 10.1208/S12248-019-0357-3  0.338
2019 Zhao J, Ren T, Yang M, Zhang Y, Wang Q, Zuo Z. Reduced systemic exposure and brain uptake of donepezil in rats with scopolamine-induced cognitive impairment. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-38. PMID 31298070 DOI: 10.1080/00498254.2019.1643514  0.331
2019 Ren T, Hu M, Cheng Y, Shek TL, Xiao M, Ho NJ, Zhang C, Leung SSY, Zuo Z. Piperine-loaded nanoparticles with enhanced dissolution and oral bioavailability for epilepsy control. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 104988. PMID 31291598 DOI: 10.1016/J.Ejps.2019.104988  0.314
2019 Ji X, Yang M, Or KH, Yim WS, Zuo Z. Tissue Accumulations of Toxic Aconitum Alkaloids after Short-Term and Long-Term Oral Administrations of Clinically Used Preparations in Rats. Toxins. 11. PMID 31216736 DOI: 10.3390/Toxins11060353  0.334
2019 Li Z, Zhang J, Zhang Y, Zuo Z. Role of esterase mediated hydrolysis of simvastatin in human and rat blood and its impact on pharmacokinetic profiles of simvastatin and its active metabolite in rat. Journal of Pharmaceutical and Biomedical Analysis. 168: 13-22. PMID 30776567 DOI: 10.1016/J.Jpba.2019.02.004  0.357
2018 Yang M, Zhang Q, Wang Q, Sørensen KK, Boesen JT, Ma SY, Jensen KJ, Kwan KM, Ngo JCK, Chan HYE, Zuo Z. Brain-targeting delivery of two peptidylic inhibitors for their combination therapy in transgenic polyglutamine disease mice via intranasal administration. Molecular Pharmaceutics. PMID 30392378 DOI: 10.1021/Acs.Molpharmaceut.8B00938  0.307
2018 Wang Q, Peng S, Hu Y, Wong CH, Kwan KM, Edwin Chan HY, Zuo Z. Efficient brain uptake and distribution of an expanded CAG RNA inhibitor DB213 via intranasal administration. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 30391403 DOI: 10.1016/J.Ejps.2018.10.025  0.315
2018 Yang M, Ji X, Zuo Z. Relationships between the Toxicities of Radix Aconiti Lateralis Preparata (Fuzi) and the Toxicokinetics of Its Main Diester-Diterpenoid Alkaloids. Toxins. 10. PMID 30261585 DOI: 10.3390/Toxins10100391  0.316
2018 Deng J, Jhandey A, Zhu X, Yang Z, Yik KFP, Zuo Z, Lam TN. In silico drug absorption tract: An agent-based biomimetic model for human oral drug absorption. Plos One. 13: e0203361. PMID 30169515 DOI: 10.1371/Journal.Pone.0203361  0.315
2018 Wang Q, Zuo Z. Impact of transporters and enzymes from blood-cerebrospinal fluid barrier and brain parenchyma on CNS drug uptake. Expert Opinion On Drug Metabolism & Toxicology. PMID 30118608 DOI: 10.1080/17425255.2018.1513493  0.301
2018 Qian S, He L, Wang Q, Wong YC, Mak M, Ho CY, Han Y, Zuo Z. Intranasal delivery of a novel acetylcholinesterase inhibitor HLS-3 for treatment of Alzheimer's disease. Life Sciences. PMID 29966606 DOI: 10.1016/J.Lfs.2018.06.032  0.502
2018 Gao Q, Yang M, Zuo Z. Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L. Acta Pharmacologica Sinica. PMID 29698388 DOI: 10.1038/Aps.2018.32  0.316
2017 Wang Q, Zhang Y, Wong CH, Edwin Chan HY, Zuo Z. Demonstration of Direct Nose-to-Brain Transport of Unbound HIV-1 Replication Inhibitor DB213 Via Intranasal Administration by Pharmacokinetic Modeling. The Aaps Journal. 20: 23. PMID 29282567 DOI: 10.1208/S12248-017-0179-0  0.316
2017 Ren T, Wang Q, Li C, Yang M, Zuo Z. Efficient Brain Uptake of Piperine and Its Pharmacokinetics Characterization after Oral Administration. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-27. PMID 29160763 DOI: 10.1080/00498254.2017.1405293  0.319
2017 Qian C, Luo X, Yang M, Jin J, Zuo Z. Impaired liver cytochrome P450 2C11 activity after dual antiplatelet therapy with aspirin and clopidogrel in rats. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-29. PMID 29052493 DOI: 10.1080/00498254.2017.1380242  0.337
2017 Fong SYK, Li C, Ho YC, Li R, Wang Q, Wong YC, Xue H, Zuo Z. Brain uptake of bioactive flavones in Scutellariae Radix and its relationship to anxiolytic effect in mice. Molecular Pharmaceutics. PMID 28426226 DOI: 10.1021/Acs.Molpharmaceut.7B00029  0.311
2016 Ge B, Zhang Z, Lam TT, Zuo Z. Puerarin offsets the anticoagulation effect of Warfarin in rats by inducing rCyps, upregulating vitamin K epoxide reductase and inhibiting thrombomodulin. Biopharmaceutics & Drug Disposition. PMID 27925234 DOI: 10.1002/Bdd.2054  0.314
2016 Au KY, Shi WW, Qian S, Zuo Z, Shaw PC. Improvement of the Pharmacological Properties of Maize RIP by Cysteine-Specific PEGylation. Toxins. 8. PMID 27763506 DOI: 10.3390/Toxins8100298  0.503
2016 Shen YX, Zhao YL, Zhang J, Zuo ZT, Wang YZ, Zhang QZ. [Study on Different Parts of Wild and Cultivated Gentiana Rigescens with Fourier Transform Infrared Spectroscopy]. Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu. 36: 667-71. PMID 27400502  0.322
2016 Li C, Wang Q, Ren T, Zhang Y, Lam CW, Chow MS, Zuo Z. Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats. Journal of Pharmaceutical and Biomedical Analysis. 128: 286-293. PMID 27288758 DOI: 10.1016/J.Jpba.2016.05.041  0.365
2016 Di Z, Zhao YL, Zuo ZT, Long H, Zhang X, Wang YZ, Li L. [Analysis and Discrimination of the Medicinal Plants Swertia Davidi Franch Based on Infrared Spectroscopy]. Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu. 36: 388-93. PMID 27209737  0.325
2016 Chu BW, Zhang J, Li ZM, Zhao YL, Zuo ZT, Wang YZ, Li WY. Evaluation and quantitative analysis of different growth periods of herb-arbor intercropping systems using HPLC and UV-vis methods coupled with chemometrics. Journal of Natural Medicines. PMID 27193013 DOI: 10.1007/s11418-016-1009-x  0.346
2016 Wang Y, Li M, Qian S, Zhang Q, Zhou L, Zuo Z, Lee B, Toh M, Ho T. Zolpidem Mucoadhesive Formulations for Intranasal Delivery: Characterization, In Vitro Permeability, Pharmacokinetics, and Nasal Ciliotoxicity in Rats. Journal of Pharmaceutical Sciences. PMID 27189774 DOI: 10.1016/J.Xphs.2016.03.035  0.615
2016 Yu S, Cai X, Sun L, Zuo Z, Mipam T, Cao S, Shen L, Ren Z, Chen X, Yang F, Deng J, Ma X, Wang Y. Comparative iTRAQ proteomics revealed proteins associated with spermatogenic arrest of cattleyak. Journal of Proteomics. PMID 27153760 DOI: 10.1016/j.jprot.2016.04.049  0.324
2016 Cao ZT, Chen ZY, Sun CY, Li HJ, Wang HX, Cheng QQ, Zuo ZQ, Wang JL, Liu YZ, Wang YC, Wang J. Overcoming tumor resistance to cisplatin by cationic lipid-assisted prodrug nanoparticles. Biomaterials. 94: 9-19. PMID 27088406 DOI: 10.1016/J.Biomaterials.2016.04.001  0.35
2016 Wang Q, Zhang Y, Qian S, Peng S, Zhang Q, Wong CH, Chan HY, Zuo Z. Pharmacokinetics and brain uptake of HIV-1 replication inhibitor DB213 in Sprague-Dawley rats. Journal of Pharmaceutical and Biomedical Analysis. 125: 41-47. PMID 26999321 DOI: 10.1016/J.Jpba.2016.03.025  0.547
2016 Ge B, Zhang Z, Zuo Z. Radix Puerariae lobatae (Gegen) suppresses the anticoagulation effect of warfarin: a pharmacokinetic and pharmacodynamics study. Chinese Medicine. 11: 7. PMID 26925159 DOI: 10.1186/S13020-016-0078-9  0.324
2016 Huo L, Wang Y, Gong Y, Krishnamurthy S, Wang J, Diao L, Liu CG, Liu X, Lin F, Symmans WF, Wei W, Zhang X, Sun L, Alvarez RH, Ueno NT, ... ... Zuo Z, et al. MicroRNA expression profiling identifies decreased expression of miR-205 in inflammatory breast cancer. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 26916073 DOI: 10.1038/Modpathol.2016.38  0.3
2016 Wang Y, Han R, Zuo Z. Dexmedetomidine post-treatment induces neuroprotection via activation of extracellular signal-regulated kinase in rats with subarachnoid haemorrhage. British Journal of Anaesthesia. 116: 384-92. PMID 26865131 DOI: 10.1093/bja/aev549  0.367
2016 Ren Z, Wang Y, Deng H, Deng Y, Deng J, Zuo Z, Wang Y, Peng X, Cui H, Shen L, Yu S, Cao S. Effects of deoxynivalenol on calcium homeostasis of concanavalin A-Stimulated splenic lymphocytes of chickens in vitro. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Fur Toxikologische Pathologie. PMID 26809658 DOI: 10.1016/j.etp.2016.01.001  0.337
2016 Lyu C, Zhang Y, Zhou W, Zhang S, Kou F, Wei H, Zhang N, Zuo Z. Gender-Dependent Pharmacokinetics of Veratramine in Rats: In Vivo and In Vitro Evidence. The Aaps Journal. PMID 26791530 DOI: 10.1208/S12248-016-9870-9  0.318
2016 Li Z, Chen P, Su R, Hu C, Li Y, Elkahloun AG, Zuo Z, Gurbuxani S, Arnovitz S, Weng H, Wang Y, Li S, Huang H, Neilly MB, Wang GG, et al. PBX3 and MEIS1 cooperate in hematopoietic cells to drive acute myeloid leukemias characterized by a core transcriptome of the MLL-rearranged disease. Cancer Research. PMID 26747896 DOI: 10.1158/0008-5472.Can-15-1566  0.332
2015 Zuo Z, Liu J, Nan J, Fan L, Sun W, Wang Y, Luan X. Highly Stereoselective Synthesis of Imine-Containing Dibenzo[b,d]azepines by a Palladium(II)-Catalyzed [5+2] Oxidative Annulation of o-Arylanilines with Alkynes. Angewandte Chemie (International Ed. in English). 54: 15385-9. PMID 26768530 DOI: 10.1002/anie.201508850  0.31
2015 Zuo ZQ, Chen KG, Yu XY, Zhao G, Shen S, Cao ZT, Luo YL, Wang YC, Wang J. Promoting tumor penetration of nanoparticles for cancer stem cell therapy by TGF-β signaling pathway inhibition. Biomaterials. 82: 48-59. PMID 26751819 DOI: 10.1016/j.biomaterials.2015.12.014  0.337
2015 Ren ZH, Deng HD, Wang YC, Deng JL, Zuo ZC, Wang Y, Peng X, Cui HM, Fang J, Yu SM, Shen LH, Hu YC. The Fusarium toxin zearalenone and deoxynivalenol affect murine splenic antioxidant functions, interferon levels, and T-cell subsets. Environmental Toxicology and Pharmacology. 41: 195-200. PMID 26722803 DOI: 10.1016/j.etap.2015.12.007  0.326
2015 Zuo ZX, Wang YJ, Liu L, Wang Y, Mei SH, Feng ZH, Wang M, Li XY. Huperzine A Alleviates Mechanical Allodynia but Not Spontaneous Pain via Muscarinic Acetylcholine Receptors in Mice. Neural Plasticity. 2015: 453170. PMID 26697233 DOI: 10.1155/2015/453170  0.319
2015 Yang YX, Luo Q, Hou B, Yan YM, Wang YH, Tang JJ, Dong XP, Ma XY, Yang TH, Zuo ZL, Cheng YX. Periplanosides A-C: new insect-derived dihydroisocoumarin glucosides from Periplaneta americana stimulating collagen production in human dermal fibroblasts. Journal of Asian Natural Products Research. 17: 988-95. PMID 26499169 DOI: 10.1080/10286020.2015.1047771  0.343
2015 Liang Z, Ren Z, Gao S, Chen Y, Yang Y, Yang D, Deng J, Zuo Z, Wang Y, Shen L. Individual and combined effects of deoxynivalenol and zearalenone on mouse kidney. Environmental Toxicology and Pharmacology. 40: 686-691. PMID 26407231 DOI: 10.1016/j.etap.2015.08.029  0.341
2015 Gao D, Wu M, Wang C, Wang Y, Zuo Z. Chronic exposure to low benzo[a]pyrene level causes neurodegenerative disease-like syndromes in zebrafish (Danio rerio). Aquatic Toxicology (Amsterdam, Netherlands). 167: 200-208. PMID 26349946 DOI: 10.1016/j.aquatox.2015.08.013  0.338
2015 Zhang J, Wang HM, Zhao YL, Zuo ZT, Wang YZ, Jin H. Comparison of Mineral Element Content in a Functional Food Maca (Lepidium meyenii Walp.) from Asia and South America. Journal of Analytical Methods in Chemistry. 2015: 530541. PMID 26236540 DOI: 10.1155/2015/530541  0.312
2015 Fong SY, Zhang Y, Wong YC, Zhou L, Han Q, Zuo Z. Identification and dispositions of novel mono-hydroxyl mefenamic acid and their potentially toxic 1-O-acyl-glucuronides in vivo. Biopharmaceutics & Drug Disposition. PMID 26109199 DOI: 10.1002/Bdd.1964  0.335
2015 Pan Y, Zhang J, Shen T, Zhao YL, Zuo ZT, Wang YZ, Li WY. Investigation of chemical diversity in different parts and origins of ethnomedicine Gentiana rigescens Franch using targeted metabolite profiling and multivariate statistical analysis. Biomedical Chromatography : Bmc. PMID 26094855 DOI: 10.1002/bmc.3540  0.379
2015 Fong SY, Wong YC, Xie C, Zuo Z. Herb-drug interactions between Scutellariae Radix and mefenamic acid: Simultaneous investigation of pharmacokinetics, anti-inflammatory effect and gastric damage in rats. Journal of Ethnopharmacology. 170: 106-16. PMID 25980420 DOI: 10.1016/J.Jep.2015.04.036  0.319
2015 Tan H, Bi J, Wang Y, Zhang J, Zuo Z. Transfusion of Old RBCs Induces Neuroinflammation and Cognitive Impairment. Critical Care Medicine. 43: e276-86. PMID 25860202 DOI: 10.1097/CCM.0000000000001023  0.3
2015 Wang Y, Zhang C, Gong T, Zuo Z, Zhao F, Fan X, Yang C, Song C. An upp-based markerless gene replacement method for genome reduction and metabolic pathway engineering in Pseudomonas mendocina NK-01 and Pseudomonas putida KT2440. Journal of Microbiological Methods. 113: 27-33. PMID 25828098 DOI: 10.1016/j.mimet.2015.03.022  0.304
2015 Lyu C, Zhou W, Zhang Y, Zhang S, Kou F, Wei H, Zhang N, Zuo Z. Identification and characterization of in vitro and in vivo metabolites of steroidal alkaloid veratramine. Biopharmaceutics & Drug Disposition. 36: 308-24. PMID 25765359 DOI: 10.1002/Bdd.1942  0.31
2015 Zuo Z, Yang X, Liu J, Nan J, Bai L, Wang Y, Luan X. Ru(II)-catalyzed oxidative spiroannulation of 2-arylphenols with alkynes via a C-H activation/dearomatization strategy. The Journal of Organic Chemistry. 80: 3349-56. PMID 25723782 DOI: 10.1021/acs.joc.5b00316  0.318
2015 Liao F, Hu Y, Wu L, Tan H, Luo B, He Y, Qiao Y, Mo Q, Wang Y, Zuo Z, Deng J, Wei Y. Induction and mechanism of HeLa cell apoptosis by 9-oxo‑10, 11-dehydroageraphorone from Eupatorium adenophorum. Oncology Reports. 33: 1823-7. PMID 25647450 DOI: 10.3892/or.2015.3778  0.334
2015 Nan J, Liu J, Zheng H, Zuo Z, Hou L, Hu H, Wang Y, Luan X. Direct asymmetric dearomatization of 2-naphthols by scandium-catalyzed electrophilic amination. Angewandte Chemie (International Ed. in English). 54: 2356-60. PMID 25564754 DOI: 10.1002/anie.201409565  0.308
2015 Ren Z, Wang Y, Deng H, Deng Y, Deng J, Zuo Z, Wang Y, Peng X, Cui H, Shen L. Deoxynivalenol induces apoptosis in chicken splenic lymphocytes via the reactive oxygen species-mediated mitochondrial pathway. Environmental Toxicology and Pharmacology. 39: 339-46. PMID 25553575 DOI: 10.1016/j.etap.2014.11.028  0.35
2015 Zhang Y, Aubry JF, Zhang J, Wang Y, Roy J, Mata JF, Miller W, Dumont E, Xie M, Lee K, Zuo Z, Wintermark M. Defining the optimal age for focal lesioning in a rat model of transcranial HIFU. Ultrasound in Medicine & Biology. 41: 449-55. PMID 25542495 DOI: 10.1016/J.Ultrasmedbio.2014.09.029  0.354
2015 Liu X, Zhou X, Zhong Z, Zuo Z, Shi J, Wang Y, Qing B, Peng G. Occurrence of novel and rare subtype families of Cryptosporidium in bamboo rats (Rhizomys sinensis) in China. Veterinary Parasitology. 207: 144-8. PMID 25499825 DOI: 10.1016/j.vetpar.2014.11.009  0.334
2015 Gu Y, Wang Y, Ma X, Wang C, Yue G, Zhang Y, Zhang Y, Li S, Ling S, Liu X, Wen X, Cao S, Huang X, Deng J, Zuo Z, et al. Greater taxol yield of fungus Pestalotiopsis hainanensis from dermatitic scurf of the giant panda (Ailuropoda melanoleuca). Applied Biochemistry and Biotechnology. 175: 155-65. PMID 25245682 DOI: 10.1007/s12010-014-1254-y  0.342
2014 Qian S, He L, Mak M, Han Y, Ho CY, Zuo Z. Synthesis, biological activity, and biopharmaceutical characterization of tacrine dimers as acetylcholinesterase inhibitors. International Journal of Pharmaceutics. 477: 442-53. PMID 25445524 DOI: 10.1016/J.Ijpharm.2014.10.058  0.536
2014 Zhang Y, Wang Y, Zuo Z, Wang Z, Roy J, Hou Q, Tong E, Hoffmann A, Sperberg E, Bredno J, Berr SS, Xie M, Lee K, Wintermark M. Effects of tissue plasminogen activator timing on blood-brain barrier permeability and hemorrhagic transformation in rats with transient ischemic stroke. Journal of the Neurological Sciences. 347: 148-54. PMID 25292413 DOI: 10.1016/J.Jns.2014.09.036  0.339
2014 Zuo Z, Che X, Wang Y, Li B, Li J, Dai W, Lin CP, Huang C. High mobility group Box-1 inhibits cancer cell motility and metastasis by suppressing activation of transcription factor CREB and nWASP expression. Oncotarget. 5: 7458-70. PMID 25277185 DOI: 10.18632/Oncotarget.2150  0.333
2014 Gao Q, Zhang Y, Wo S, Zuo Z. Elucidation of arctigenin pharmacokinetics after intravenous and oral administrations in rats: integration of in vitro and in vivo findings via semi-mechanistic pharmacokinetic modeling. The Aaps Journal. 16: 1321-33. PMID 25274606 DOI: 10.1208/S12248-014-9664-X  0.34
2014 Qian S, Wang Q, Zuo Z. Improved brain uptake of peptide-based CNS drugs via alternative routes of administrations of its nanocarrier delivery systems: a promising strategy for CNS targeting delivery of peptides. Expert Opinion On Drug Metabolism & Toxicology. 10: 1491-508. PMID 25196358 DOI: 10.1517/17425255.2014.956080  0.501
2014 Li XY, Wang N, Wang YJ, Zuo ZX, Koga K, Luo F, Zhuo M. Long-term temporal imprecision of information coding in the anterior cingulate cortex of mice with peripheral inflammation or nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10675-87. PMID 25100600 DOI: 10.1523/Jneurosci.5166-13.2014  0.314
2014 Zhang Z, Ge B, Zhou L, Lam TN, Zuo Z. Induction of liver cytochrome P450s by Danshen-Gegen formula is the leading cause for its pharmacokinetic interactions with warfarin. Journal of Ethnopharmacology. 154: 672-86. PMID 24832110 DOI: 10.1016/J.Jep.2014.04.047  0.334
2014 Fong SY, Wong YC, Zuo Z. Development of a SPE-LC/MS/MS method for simultaneous quantification of baicalein, wogonin, oroxylin A and their glucuronides baicalin, wogonoside and oroxyloside in rats and its application to brain uptake and plasma pharmacokinetic studies. Journal of Pharmaceutical and Biomedical Analysis. 97: 9-23. PMID 24803030 DOI: 10.1016/J.Jpba.2014.03.033  0.338
2014 Qian S, Wong YC, Zuo Z. Development, characterization and application of in situ gel systems for intranasal delivery of tacrine. International Journal of Pharmaceutics. 468: 272-82. PMID 24709220 DOI: 10.1016/J.Ijpharm.2014.04.015  0.55
2014 Wong YC, Qian S, Zuo Z. Pharmacokinetic comparison between the long-term anesthetized, short-term anesthetized and conscious rat models in nasal drug delivery. Pharmaceutical Research. 31: 2107-23. PMID 24554118 DOI: 10.1007/S11095-014-1312-8  0.524
2014 Chang Q, Wo S, Ngai KL, Wang X, Fok B, Ngan TM, Wong VT, Chan TY, Lee VH, Tomlinson B, Chan PK, Chow MS, Zuo Z. Bench to bed evidences for pharmacokinetic and pharmacodynamic interactions involving oseltamivir and chinese medicine. Evidence-Based Complementary and Alternative Medicine : Ecam. 2014: 354172. PMID 24527044 DOI: 10.1155/2014/354172  0.538
2014 Liu M, Ravula R, Wang Z, Zuo Z, Chow MS, Thakkar A, Prabhu S, Andresen B, Huang Y. Traditional Chinese medicinal formula Si-Wu-Tang prevents oxidative damage by activating Nrf2-mediated detoxifying/antioxidant genes. Cell & Bioscience. 4: 8. PMID 24507416 DOI: 10.1186/2045-3701-4-8  0.316
2014 Gao Q, Zhang Y, Wo S, Zuo Z. Extensive intestinal first-pass metabolism of arctigenin: evidenced by simultaneous monitoring of both parent drug and its major metabolites. Journal of Pharmaceutical and Biomedical Analysis. 91: 60-7. PMID 24434279 DOI: 10.1016/J.Jpba.2013.12.017  0.364
2014 Fong SY, Zuo Z. Species difference in the inhibitory potentials of non-steroidal anti-inflammatory drugs on the hepatic sulfation and glucuronidation of bioactive flavonoids: differential observations among common inhibition parameters. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 44: 417-31. PMID 24168065 DOI: 10.3109/00498254.2013.851431  0.302
2014 Li C, Fong SY, Mei Q, Lin G, Zuo Z. Influence of mefenamic acid on the intestinal absorption and metabolism of three bioactive flavones in Radix Scutellariae and potential pharmacological impact. Pharmaceutical Biology. 52: 291-7. PMID 24102566 DOI: 10.3109/13880209.2013.834366  0.305
2013 Qian S, Zhang Q, Wang Y, Lee B, Betageri GV, Chow MS, Huang M, Zuo Z. Bioavailability enhancement of glucosamine hydrochloride by chitosan. International Journal of Pharmaceutics. 455: 365-73. PMID 23830943 DOI: 10.1016/J.Ijpharm.2013.06.055  0.622
2013 Wong YC, Zuo Z. Brain disposition and catalepsy after intranasal delivery of loxapine: role of metabolism in PK/PD of intranasal CNS drugs. Pharmaceutical Research. 30: 2368-84. PMID 23739987 DOI: 10.1007/S11095-013-1080-X  0.341
2013 Xie C, Wang Z, Wang C, Xu J, Wen Z, Wang H, Shi L, Chow MS, Huang Y, Zuo Z. Utilization of gene expression signature for quality control of traditional Chinese medicine formula Si-Wu-Tang. The Aaps Journal. 15: 884-92. PMID 23703112 DOI: 10.1208/S12248-013-9491-5  0.301
2013 Wang Y, Wang Z, Zuo Z, Tomlinson B, Lee BT, Bolger MB, Chow MS. Clinical pharmacokinetics of buffered propranolol sublingual tablet (Promptol™)-application of a new "physiologically based" model to assess absorption and disposition. The Aaps Journal. 15: 787-96. PMID 23605805 DOI: 10.1208/S12248-013-9479-1  0.471
2013 Zhang C, Chanteux H, Zuo Z, Kwan P, Baum L. Potential role for human P-glycoprotein in the transport of lacosamide. Epilepsia. 54: 1154-60. PMID 23551115 DOI: 10.1111/Epi.12158  0.302
2013 Gao Q, Zhang Y, Wo S, Zuo Z. Hydrolysis is the dominating in vivo metabolism pathway for arctigenin: identification of novel metabolites of arctigenin by LC/MS/MS after oral administration in rats. Planta Medica. 79: 471-9. PMID 23519790 DOI: 10.1055/S-0032-1328332  0.337
2013 Zuo Z, Zhang L, Zhou L. Intestinal Absorption and Disposition of Green Tea Catechins: The First Barrier for Green Tea Catechins Entering the Body Tea in Health and Disease Prevention. 399-412. DOI: 10.1016/B978-0-12-384937-3.00033-1  0.315
2012 Li CR, Zhang L, Wo SK, Zhou LM, Lin G, Zuo Z. Pharmacokinetic interactions among major bioactive components in Radix Scutellariae via metabolic competition. Biopharmaceutics & Drug Disposition. 33: 487-500. PMID 22933367 DOI: 10.1002/Bdd.1815  0.37
2012 Zhou L, Wang S, Zhang Z, Lau BS, Fung KP, Leung PC, Zuo Z. Pharmacokinetic and pharmacodynamic interaction of Danshen-Gegen extract with warfarin and aspirin. Journal of Ethnopharmacology. 143: 648-55. PMID 22867637 DOI: 10.1016/J.Jep.2012.07.029  0.339
2012 Wong YC, Qian S, Zuo Z. Regioselective biotransformation of CNS drugs and its clinical impact on adverse drug reactions. Expert Opinion On Drug Metabolism & Toxicology. 8: 833-54. PMID 22568396 DOI: 10.1517/17425255.2012.688027  0.536
2012 Qian S, Li C, Zuo Z. Pharmacokinetics and disposition of various drug loaded liposomes. Current Drug Metabolism. 13: 372-95. PMID 22443534 DOI: 10.2174/138920012800166562  0.532
2012 Qian S, Wo SK, Zuo Z. Pharmacokinetics and brain dispositions of tacrine and its major bioactive monohydroxylated metabolites in rats. Journal of Pharmaceutical and Biomedical Analysis. 61: 57-63. PMID 22196801 DOI: 10.1016/J.Jpba.2011.11.025  0.556
2012 Li C, Zhang L, Zhou L, Wo SK, Lin G, Zuo Z. Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae. The Aaps Journal. 14: 23-34. PMID 22167378 DOI: 10.1208/S12248-011-9310-9  0.341
2012 Wong YC, Wo SK, Zuo Z. Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis. 58: 83-93. PMID 21993198 DOI: 10.1016/J.Jpba.2011.09.020  0.35
2012 Fong YK, Li CR, Wo SK, Wang S, Zhou L, Zhang L, Lin G, Zuo Z. In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein. Journal of Ethnopharmacology. 141: 742-53. PMID 21906668 DOI: 10.1016/J.Jep.2011.08.042  0.34
2012 Liu MM, Fan J, Wang Z, Zuo Z, Chow M, Huang Y. Abstract B50: Evaluation of cancer preventive activity of Chinese medicinal formula Si-Wu-Tang Cancer Prevention Research. 5. DOI: 10.1158/1940-6207.Prev-12-B50  0.319
2011 Li C, Lin G, Zuo Z. Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones. Biopharmaceutics & Drug Disposition. 32: 427-45. PMID 21928297 DOI: 10.1002/Bdd.771  0.32
2011 Wang S, Chow MS, Zuo Z. An approach for rapid development of nasal delivery of analgesics--identification of relevant features, in vitro screening and in vivo verification. International Journal of Pharmaceutics. 420: 43-50. PMID 21871544 DOI: 10.1016/J.Ijpharm.2011.08.019  0.342
2011 Zhang C, Zuo Z, Kwan P, Baum L. In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein. Epilepsia. 52: 1894-904. PMID 21692796 DOI: 10.1111/J.1528-1167.2011.03140.X  0.312
2011 Zhang L, Li C, Lin G, Krajcsi P, Zuo Z. Hepatic metabolism and disposition of baicalein via the coupling of conjugation enzymes and transporters-in vitro and in vivo evidences. The Aaps Journal. 13: 378-89. PMID 21607811 DOI: 10.1208/S12248-011-9277-6  0.327
2011 Yu H, Hu YQ, Ip FC, Zuo Z, Han YF, Ip NY. Intestinal transport of bis(12)-hupyridone in Caco-2 cells and its improved permeability by the surfactant Brij-35. Biopharmaceutics & Drug Disposition. 32: 140-50. PMID 21271607 DOI: 10.1002/Bdd.745  0.304
2011 Li C, Zhang L, Lin G, Zuo Z. Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product. Journal of Pharmaceutical and Biomedical Analysis. 54: 750-8. PMID 21051171 DOI: 10.1016/J.Jpba.2010.10.005  0.36
2010 Wong YC, Zuo Z. Intranasal delivery--modification of drug metabolism and brain disposition. Pharmaceutical Research. 27: 1208-23. PMID 20372990 DOI: 10.1007/S11095-010-0127-5  0.325
2010 Wang Y, Zuo Z, Chen X, Tomlinson B, Chow MS. Improving sublingual delivery of weak base compounds using pH(max) concept: application to propranolol. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 39: 272-8. PMID 20060467 DOI: 10.1016/J.Ejps.2009.12.011  0.444
2010 Lin ZX, Jiao BW, Che CT, Zuo Z, Mok CF, Zhao M, Ho WK, Tse WP, Lam KY, Fan RQ, Yang ZJ, Cheng CH. Ethyl acetate fraction of the root of Rubia cordifolia L. inhibits keratinocyte proliferation in vitro and promotes keratinocyte differentiation in vivo: potential application for psoriasis treatment. Phytotherapy Research : Ptr. 24: 1056-64. PMID 19960426 DOI: 10.1002/Ptr.3079  0.307
2009 Zhou L, Chow MS, Zuo Z. Effect of sodium caprate on the oral absorptions of danshensu and salvianolic acid B. International Journal of Pharmaceutics. 379: 109-18. PMID 19555749 DOI: 10.1016/J.Ijpharm.2009.06.016  0.357
2009 Li C, Zhou L, Lin G, Zuo Z. Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae. Journal of Pharmaceutical and Biomedical Analysis. 50: 298-306. PMID 19481403 DOI: 10.1016/J.Jpba.2009.04.028  0.302
2009 Chang Q, Chow MS, Zuo Z. Studies on the influence of esterase inhibitor to the pharmacokinetic profiles of oseltamivir and oseltamivir carboxylate in rats using an improved LC/MS/MS method. Biomedical Chromatography : Bmc. 23: 852-7. PMID 19353695 DOI: 10.1002/Bmc.1195  0.512
2009 Zhou X, Leung PH, Li N, Ye Y, Zhang L, Zuo Z, Lin G. Oral absorption and antitussive activity of tuberostemonine alkaloids from the roots of Stemona tuberosa. Planta Medica. 75: 575-80. PMID 19214944 DOI: 10.1055/S-0029-1185363  0.341
2009 Yu H, Li WM, Cheung MC, Zuo Z, Carlier PR, Gu ZM, Chan K, Huang M, Wang YT, Han YF. Development and validation of an HPLC-DAD method for bis(12)-hupyridone and its application to a pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis. 49: 410-4. PMID 19124214 DOI: 10.1016/J.Jpba.2008.11.013  0.312
2009 Wang Y, Zuo Z, Chow MS. HO-1-u-1 model for screening sublingual drug delivery--influence of pH, osmolarity and permeation enhancer. International Journal of Pharmaceutics. 370: 68-74. PMID 19071203 DOI: 10.1016/J.Ijpharm.2008.11.010  0.46
2009 Wong YC, Zhang L, Lin G, Zuo Z. Intestinal first-pass glucuronidation activities of selected dihydroxyflavones. International Journal of Pharmaceutics. 366: 14-20. PMID 18809479 DOI: 10.1016/J.Ijpharm.2008.08.035  0.326
2008 Chang Q, Sun L, Zhao RH, Chow MS, Zuo Z. Simultaneous determination of ten active components in traditional Chinese medicinal products containing both Gegen (Pueraria lobata) and Danshen (Salvia miltiorrhiza) by high-performance liquid chromatography. Phytochemical Analysis : Pca. 19: 368-75. PMID 18438756 DOI: 10.1002/Pca.1063  0.508
2008 Zhang L, Yu H, Li WM, Cheung MC, Pang YP, Gu ZM, Chan K, Wang YT, Zuo Z, Han YF. Preclinical characterization of intestinal absorption and metabolism of promising anti-Alzheimer's dimer bis(7)-tacrine. International Journal of Pharmaceutics. 357: 85-94. PMID 18358649 DOI: 10.1016/J.Ijpharm.2008.01.037  0.335
2008 Pan Y, Bi H-, Zhong G-, Chen X, Zuo Z, Zhao L-, Gu L-, Liu P-, Huang Z-, Zhou S-, Huang M. Pharmacokinetic characterization of hydroxylpropyl-β-cyclodextrin-included complex of cryptotanshinone, an investigational cardiovascular drug purified from Danshen (Salvia miltiorrhiza) Xenobiotica. 38: 382-398. PMID 18340563 DOI: 10.1080/00498250701827685  0.336
2008 Bi HC, Zuo Z, Chen X, Xu CS, Wen YY, Sun HY, Zhao LZ, Pan Y, Deng Y, Liu PQ, Gu LQ, Huang ZY, Zhou SF, Huang M. Preclinical factors affecting the pharmacokinetic behaviour of tanshinone IIA, an investigational new drug isolated from Salvia miltiorrhiza for the treatment of ischaemic heart diseases. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 38: 185-222. PMID 18197559 DOI: 10.1080/00498250701767675  0.38
2008 Wang Y, Chow MS, Zuo Z. Mechanistic analysis of pH-dependent solubility and trans-membrane permeability of amphoteric compounds: application to sildenafil. International Journal of Pharmaceutics. 352: 217-24. PMID 18068319 DOI: 10.1016/J.Ijpharm.2007.10.039  0.415
2007 Zhang L, Zuo Z, Lin G. Intestinal and hepatic glucuronidation of flavonoids. Molecular Pharmaceutics. 4: 833-45. PMID 17979245 DOI: 10.1021/Mp700077Z  0.333
2007 Wang Y, Zuo Z, Lee KK, Chow MS. Evaluation of HO-1-u-1 cell line as an in vitro model for sublingual drug delivery involving passive diffusion--Initial validation studies. International Journal of Pharmaceutics. 334: 27-34. PMID 17079100 DOI: 10.1016/J.Ijpharm.2006.10.012  0.46
2006 Zuo Z, Zhang L, Zhou L, Chang Q, Chow M. Intestinal absorption of hawthorn flavonoids--in vitro, in situ and in vivo correlations. Life Sciences. 79: 2455-62. PMID 16989871 DOI: 10.1016/J.Lfs.2006.08.014  0.545
2006 Leung PH, Zhang L, Zuo Z, Lin G. Intestinal absorption of Stemona alkaloids in a Caco-2 cell model. Planta Medica. 72: 211-6. PMID 16534724 DOI: 10.1055/S-2005-916195  0.317
2006 Zhang L, Chow MS, Zuo Z. Effect of the co-occurring components from green tea on the intestinal absorption and disposition of green tea polyphenols in Caco-2 monolayer model. The Journal of Pharmacy and Pharmacology. 58: 37-44. PMID 16393462 DOI: 10.1211/Jpp.58.1.0005  0.345
2006 Zhang L, Lin G, Zuo Z. Position preference on glucuronidation of mono-hydroxylflavones in human intestine. Life Sciences. 78: 2772-80. PMID 16376382 DOI: 10.1016/J.Lfs.2005.10.038  0.324
2006 Chang Q, Zuo Z, Chow MS, Ho WK. Effect of storage temperature on phenolics stability in hawthorn (Crataegus pinnatifida var. major) fruits and a hawthorn drink Food Chemistry. 98: 426-430. DOI: 10.1016/J.Foodchem.2005.06.015  0.449
2005 Zhang L, Lin G, Chang Q, Zuo Z. Role of intestinal first-pass metabolism of baicalein in its absorption process. Pharmaceutical Research. 22: 1050-8. PMID 16028005 DOI: 10.1007/S11095-005-5303-7  0.505
2005 Chen X, Yin OQ, Zuo Z, Chow MS. Pharmacokinetics and modeling of quercetin and metabolites. Pharmaceutical Research. 22: 892-901. PMID 15948033 DOI: 10.1007/S11095-005-4584-1  0.364
2005 Chang Q, Zuo Z, Chow MS, Ho WK. Difference in absorption of the two structurally similar flavonoid glycosides, hyperoside and isoquercitrin, in rats. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 59: 549-55. PMID 15760736 DOI: 10.1016/J.Ejpb.2004.10.004  0.547
2005 Chang Q, Zuo Z, Ho WK, Chow MS. Comparison of the pharmacokinetics of hawthorn phenolics in extract versus individual pure compound. Journal of Clinical Pharmacology. 45: 106-12. PMID 15601812 DOI: 10.1177/0091270004270500  0.53
2004 Zhang L, Zheng Y, Chow MS, Zuo Z. Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model. International Journal of Pharmaceutics. 287: 1-12. PMID 15541906 DOI: 10.1016/J.Ijpharm.2004.08.020  0.325
2004 Zhang L, Lin G, Zuo Z. High-performance liquid chromatographic method for simultaneous determination of baicalein and baicalein 7-glucuronide in rat plasma. Journal of Pharmaceutical and Biomedical Analysis. 36: 637-41. PMID 15522542 DOI: 10.1016/J.Jpba.2004.07.024  0.306
2002 Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. Journal of Clinical Pharmacology. 42: 605-12. PMID 12043949  0.416
2001 Chang Q, Zhu M, Zuo Z, Chow M, Ho WK. High-performance liquid chromatographic method for simultaneous determination of hawthorn active components in rat plasma. Journal of Chromatography. B, Biomedical Sciences and Applications. 760: 227-35. PMID 11530981 DOI: 10.1016/S0378-4347(01)00273-0  0.519
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