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Erika L. Darrah, Ph.D. - Publications

Affiliations: 
2010 Johns Hopkins University, Baltimore, MD 
Area:
Immunology
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cappelli LC, Hines D, Wang H, Bingham CO, Darrah E. Anti-Peptidylarginine Deiminase 4 Autoantibodies and Disease Duration as Predictors of Treatment Response in Rheumatoid Arthritis. Acr Open Rheumatology. PMID 38058274 DOI: 10.1002/acr2.11630  0.593
2023 Crawford JD, Wang H, Trejo-Zambrano D, Cimbro R, Talbot CC, Thomas MA, Curran AM, Girgis AA, Schroeder JT, Fava A, Goldman DW, Petri M, Rosen A, Antiochos B, Darrah E. The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE. Jci Insight. PMID 37733447 DOI: 10.1172/jci.insight.169344  0.482
2023 Gomez-Bañuelos E, Yu Y, Li J, Cashman KS, Paz M, Trejo-Zambrano MI, Bugrovsky R, Wang Y, Chida AS, Sherman-Baust CA, Ferris DP, Goldman DW, Darrah E, Petri M, Sanz I, et al. Affinity maturation generates pathogenic antibodies with dual reactivity to DNase1L3 and dsDNA in systemic lupus erythematosus. Nature Communications. 14: 1388. PMID 36941260 DOI: 10.1038/s41467-023-37083-x  0.327
2023 Wilson TM, Solomon JJ, Humphries SM, Swigris JJ, Ahmed F, Wang H, Darrah E, Demoruelle MK. Serum Antibodies to Peptidylarginine Deiminase-4 in Rheumatoid Arthritis Associated-Interstitial Lung Disease Are Associated with Decreased Lung Fibrosis and Improved Survival. The American Journal of the Medical Sciences. PMID 36918112 DOI: 10.1016/j.amjms.2023.03.003  0.532
2023 Curran AM, Girgis AA, Jang Y, Crawford JD, Thomas MA, Kawalerski R, Coller J, Bingham CO, Na CH, Darrah E. Citrullination modulates antigen processing and presentation by revealing cryptic epitopes in rheumatoid arthritis. Nature Communications. 14: 1061. PMID 36828807 DOI: 10.1038/s41467-023-36620-y  0.503
2022 Cappelli LC, Bingham CO, Forde PM, Anagnostou V, Brahmer J, Lipson EJ, Mammen J, Schollenberger M, Shah AA, Darrah E. Anti-RA33 antibodies are present in a subset of patients with immune checkpoint inhibitor-induced inflammatory arthritis. Rmd Open. 8. PMID 36096522 DOI: 10.1136/rmdopen-2022-002511  0.537
2022 Eaton WW, Rodriguez KM, Thomas MA, Johnson J, Talor MV, Dohan C, Bingham CO, Musci R, Roth K, Kelly DL, Cihakova D, Darrah E. Immunologic profiling in schizophrenia and rheumatoid arthritis. Psychiatry Research. 317: 114812. PMID 36058039 DOI: 10.1016/j.psychres.2022.114812  0.356
2022 Gomez-Bañuelos E, Wahadat MJ, Li J, Paz M, Antiochos B, Celia AI, Andrade V, Ferris DP, Goldman DW, Darrah E, Petri M, Andrade F. Alternative exon usage in TRIM21 determines the antigenicity of Ro52/TRIM21 in systemic lupus erythematosus. Jci Insight. PMID 36040804 DOI: 10.1172/jci.insight.163795  0.353
2022 Moosic KB, Ananth K, Andrade F, Feith DJ, Darrah E, Loughran TP. Intersection Between Large Granular Lymphocyte Leukemia and Rheumatoid Arthritis. Frontiers in Oncology. 12: 869205. PMID 35646651 DOI: 10.3389/fonc.2022.869205  0.546
2021 Cappelli LC, Darrah E, Shah AA, Bingham CO. Patients with checkpoint inhibitor-induced inflammatory arthritis do not become seropositive for anti-cyclic citrullinated peptide when followed over time. Acr Open Rheumatology. PMID 34757698 DOI: 10.1002/acr2.11363  0.301
2021 Antiochos B, Paz M, Li J, Goldman DW, Petri M, Darrah E, Cashman K, Sanz I, Burns KH, Ardeljan D, Andrade F, Rosen A. Autoantibodies targeting LINE-1-encoded ORF1p are associated with systemic lupus erythematosus diagnosis but not disease activity. Clinical and Experimental Rheumatology. PMID 34665712  0.573
2021 Román-Meléndez GD, Monaco DR, Montagne JM, Quizon RS, Konig MF, Astatke M, Darrah E, Larman HB. Citrullination of a phage-displayed human peptidome library reveals the fine specificities of rheumatoid arthritis-associated autoantibodies. Ebiomedicine. 71: 103506. PMID 34481243 DOI: 10.1016/j.ebiom.2021.103506  0.436
2021 Demoruelle MK, Wang H, Davis RL, Visser A, Hoang J, Norris JM, Holers VM, Deane KD, Darrah E. Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis. Arthritis Research & Therapy. 23: 163. PMID 34092252 DOI: 10.1186/s13075-021-02528-5  0.591
2020 Gutierrez-Hoffmann MG, O'Meally RN, Cole RN, Tiniakou E, Darrah E, Soloski MJ. -Induced Changes in the Class II Self-Immunopeptidome Displayed on HLA-DR Molecules Expressed by Dendritic Cells. Frontiers in Medicine. 7: 568. PMID 33043033 DOI: 10.3389/Fmed.2020.00568  0.307
2020 Curran AM, Naik P, Giles JT, Darrah E. PAD enzymes in rheumatoid arthritis: pathogenic effectors and autoimmune targets. Nature Reviews. Rheumatology. PMID 32341463 DOI: 10.1038/S41584-020-0409-1  0.628
2020 Darrah E, Davis RL, Curran AM, Naik P, Chen R, Na CH, Giles JT, Andrade F. Citrullination Is Not a Major Determinant in the Recognition of Peptidylarginine Deiminase 2 and 4 by Autoantibodies in Rheumatoid Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 32255561 DOI: 10.1002/Art.41276  0.596
2020 Tiniakou E, Fava A, McMahan ZH, Guhr T, O'Meally RN, Shah AA, Wigley FM, Cole RN, Boin F, Darrah E. Definition of naturally processed peptides reveals convergent presentation of autoantigenic topoisomerase-I epitopes in scleroderma. Arthritis & Rheumatology (Hoboken, N.J.). PMID 32162841 DOI: 10.1002/Art.41248  0.392
2020 Cappelli LC, Thomas MA, Bingham CO, Shah AA, Darrah E. Immune checkpoint inhibitor-induced inflammatory arthritis as a model of autoimmune arthritis. Immunological Reviews. PMID 31930524 DOI: 10.1111/Imr.12832  0.464
2020 Curran AM, Crawford J, Darrah E. Op0325 Effect Of Citrullination On The Processing And Presentation Of Rheumatoid Arthritis Autoantigens Annals of the Rheumatic Diseases. 79: 200-200. DOI: 10.1136/Annrheumdis-2020-Eular.1638  0.504
2019 Romero V, Darrah E, Andrade F. Peptidylarginine deiminase type 2 and 4 generate distinct patterns of rheumatoid arthritis autoantigens during perforin-induced cell damage. Arthritis & Rheumatology (Hoboken, N.J.). PMID 31876120 DOI: 10.1002/Art.41196  0.595
2019 Fert-Bober J, Darrah E, Andrade F. Insights into the study and origin of the citrullinome in rheumatoid arthritis. Immunological Reviews. PMID 31876028 DOI: 10.1111/Imr.12834  0.603
2019 Gómez-Bañuelos E, Mukherjee A, Darrah E, Andrade F. Rheumatoid Arthritis-Associated Mechanisms of and . Journal of Clinical Medicine. 8. PMID 31454946 DOI: 10.3390/Jcm8091309  0.636
2019 Gutierrez MJ, Desiderio SV, Wang NY, Darrah E, Cappelli L, Nino G, Jones M, Bingham CO. Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis. Journal of Immunology Research. 2019: 3658215. PMID 31183387 DOI: 10.1155/2019/3658215  0.571
2019 Darrah E, Martinez-Prat L, Mahler M. Clinical Utility of Antipeptidyl Arginine Deiminase Type 4 Antibodies. The Journal of Rheumatology. 46: 329-330. PMID 30647163 DOI: 10.3899/Jrheum.180905  0.593
2018 Darrah E, Giles JT, Davis RL, Naik P, Wang H, Konig MF, Cappelli LC, Bingham CO, Danoff SK, Andrade F. Autoantibodies to Peptidylarginine Deiminase 2 Are Associated With Less Severe Disease in Rheumatoid Arthritis. Frontiers in Immunology. 9: 2696. PMID 30515171 DOI: 10.3389/Fimmu.2018.02696  0.636
2018 Darrah E, Yu F, Cappelli LC, Rosen A, O'Dell JR, Mikuls TR. Association of baseline peptidylarginine deiminase 4 autoantibodies with favorable response to treatment escalation in rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 30507066 DOI: 10.1002/Art.40791  0.707
2018 Cappelli LC, Konig MF, Gelber AC, Bingham CO, Darrah E. Smoking is not linked to the development of anti-peptidylarginine deiminase 4 autoantibodies in rheumatoid arthritis Arthritis Research & Therapy. 20: 59-59. PMID 29566742 DOI: 10.1186/S13075-018-1533-Z  0.534
2018 Darrah E, Andrade FA. Rheumatoid arthritis and citrullination. Current Opinion in Rheumatology. 30: 72-78. PMID 28937414 DOI: 10.1097/Bor.0000000000000452  0.611
2018 Gutierrez MJ, Darrah E, Cappelli L, Jones M, Bingham CO. Soluble Markers of B-cell Homing, Activation and Survival and Infection Risk in Rheumatoid Arthritis The Journal of Allergy and Clinical Immunology. 141. DOI: 10.1016/J.Jaci.2017.12.909  0.388
2017 Shi J, Darrah E, Sims GP, Mustelin T, Sampson K, Konig MF, Bingham CO, Rosen A, Andrade F. Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis. Annals of the Rheumatic Diseases. PMID 29070531 DOI: 10.1136/Annrheumdis-2017-211489  0.725
2017 Zhou Y, Chen B, Mittereder N, Chaerkady R, Strain M, An LL, Rahman S, Ma W, Low CP, Chan D, Neal F, Bingham CO, Sampson K, Darrah E, Siegel RM, et al. Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils. Frontiers in Immunology. 8: 1200. PMID 28993780 DOI: 10.3389/Fimmu.2017.01200  0.514
2017 Tiniakou E, Fava A, Gurh T, Boin F, Darrah E. 06.15 Naturally processed topoisomerase i peptides presented by dendritic cells identify immunodominant t cell epitopes in systemic sclerosis Annals of the Rheumatic Diseases. 76. DOI: 10.1136/Annrheumdis-2016-211053.15  0.338
2016 Navarro-Millán I, Darrah E, Westfall AO, Mikuls TR, Reynolds RJ, Danila MI, Curtis JR, Rosen A, Bridges SL. Association of anti-peptidyl arginine deiminase antibodies with radiographic severity of rheumatoid arthritis in African Americans. Arthritis Research & Therapy. 18: 241. PMID 27770831 DOI: 10.1186/S13075-016-1126-7  0.725
2016 Darrah E, Kim A, Zhang X, Boronina T, Cole RN, Fava A, Giles JT, Bingham Iii CO, Chalmers MJ, Griffin PR, Sadegh-Nasseri S, Rosen A. Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis. Journal of Proteome Research. PMID 27700100 DOI: 10.1021/Acs.Jproteome.6B00617  0.698
2016 Seaman A, Darrah E, Infantino M, Meacci F, Manfredi M, Benucci M, Mahler M. Anti-peptidyl-arginine deaminase 3 (PAD3) antibodies as a promising marker to measure joint damage in patients with rheumatoid arthritis. Autoimmunity Reviews. PMID 26997641 DOI: 10.1016/J.Autrev.2016.03.016  0.518
2015 Darrah E, Andrade F. Editorial: citrullination, and carbamylation, and malondialdehyde-acetaldehyde! Oh my! Entering the forest of autoantigen modifications in rheumatoid arthritis. Arthritis & Rheumatism. 67: 604-608. PMID 25469991 DOI: 10.1002/Art.38970  0.479
2014 Giles JT, Darrah E, Danoff S, Johnson C, Andrade F, Rosen A, Bathon JM. Association of cross-reactive antibodies targeting peptidyl-arginine deiminase 3 and 4 with rheumatoid arthritis-associated interstitial lung disease. Plos One. 9: e98794. PMID 24901704 DOI: 10.1371/Journal.Pone.0098794  0.733
2014 Konig MF, Darrah E, Andrade FA. Insights Into the Significance of Peptidylarginine Deiminase 4 and Antibodies Against Citrullinated Antigens in the Absence of “True ACPAs” in an Experimental Model of Arthritis: Comment on the Article by Shelef et al Arthritis & Rheumatism. 66: 2642-2644. PMID 24891314 DOI: 10.1002/Art.38719  0.375
2014 Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A. Association of the autoimmune disease scleroderma with an immunologic response to cancer. Science (New York, N.Y.). 343: 152-7. PMID 24310608 DOI: 10.1126/Science.1246886  0.608
2014 Darrah E. SP0161 Functional Consequences of Anti-Pad-Antibodies in RA Annals of the Rheumatic Diseases. 73: 43-43. DOI: 10.1136/Annrheumdis-2014-Eular.6169  0.632
2013 Romero V, Fert-Bober J, Nigrovic PA, Darrah E, Haque UJ, Lee DM, van Eyk J, Rosen A, Andrade F. Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis. Science Translational Medicine. 5: 209ra150. PMID 24174326 DOI: 10.1126/Scitranslmed.3006869  0.712
2013 Ferucci ED, Darrah E, Smolik I, Choromanski TL, Robinson DB, Newkirk MM, Fritzler MJ, Rosen A, El-Gabalawy HS. Prevalence of anti-peptidylarginine deiminase type 4 antibodies in rheumatoid arthritis and unaffected first-degree relatives in indigenous North American Populations. The Journal of Rheumatology. 40: 1523-8. PMID 23908443 DOI: 10.3899/Jrheum.130293  0.717
2013 Darrah E, Giles JT, Ols ML, Bull HG, Andrade F, Rosen A. Erosive rheumatoid arthritis is associated with antibodies that activate PAD4 by increasing calcium sensitivity. Science Translational Medicine. 5: 186ra65. PMID 23698378 DOI: 10.1126/Scitranslmed.3005370  0.71
2013 Darrah E, Andrade F. NETs: the missing link between cell death and systemic autoimmune diseases? Frontiers in Immunology. 3: 428-428. PMID 23335928 DOI: 10.3389/Fimmu.2012.00428  0.336
2012 Darrah E, Rosen A, Giles JT, Andrade F. Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis. Annals of the Rheumatic Diseases. 71: 92-8. PMID 21859690 DOI: 10.1136/Ard.2011.151712  0.706
2010 Kolfenbach JR, Deane KD, Derber LA, O'Donnell CI, Gilliland WR, Edison JD, Rosen A, Darrah E, Norris JM, Holers VM. Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis. Arthritis and Rheumatism. 62: 2633-9. PMID 20496417 DOI: 10.1002/Art.27570  0.724
2010 Andrade F, Darrah E, Gucek M, Cole RN, Rosen A, Zhu X. Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation. Arthritis and Rheumatism. 62: 1630-40. PMID 20201080 DOI: 10.1002/Art.27439  0.518
2010 Darrah E, Rosen A. Granzyme B cleavage of autoantigens in autoimmunity. Cell Death and Differentiation. 17: 624-32. PMID 20075942 DOI: 10.1038/Cdd.2009.197  0.587
2008 Harris ML, Darrah E, Lam GK, Bartlett SJ, Giles JT, Grant AV, Gao P, Scott WW, El-Gabalawy H, Casciola-Rosen L, Barnes KC, Bathon JM, Rosen A. Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis. Arthritis and Rheumatism. 58: 1958-67. PMID 18576335 DOI: 10.1002/Art.23596  0.773
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