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Jens Pahnke - Publications

Affiliations: 
Neurological Clinic University of Rostock, Rostock, Mecklenburg-Vorpommern, Germany 
Area:
Alzheimer's disease, neuropathology
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Möhle L, Stefan K, Bascuñana P, Brackhan M, Brüning T, Eiriz I, El Menuawy A, van Genderen S, Santos-García I, Górska AM, Villa M, Wu J, Stefan SM, Pahnke J. ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer's Disease. Biology. 12. PMID 37508364 DOI: 10.3390/biology12070932  0.335
2023 Farfara D, Sooliman M, Avrahami L, Royal TG, Amram S, Rozenstein-Tsalkovich L, Trudler D, Blanga-Kanfi S, Eldar-Finkelman H, Pahnke J, Rosenmann H, Frenkel D. Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice. Journal of Neuroinflammation. 20: 174. PMID 37496076 DOI: 10.1186/s12974-023-02823-9  0.342
2023 Bascuñana P, Brackhan M, Möhle L, Wu J, Brüning T, Eiriz I, Jansone B, Pahnke J. Time- and Sex-Dependent Effects of Fingolimod Treatment in a Mouse Model of Alzheimer's Disease. Biomolecules. 13. PMID 36830699 DOI: 10.3390/biom13020331  0.304
2021 Dib S, Pahnke J, Gosselet F. Role of ABCA7 in Human Health and in Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33925691 DOI: 10.3390/ijms22094603  0.33
2020 Wanek T, Zoufal V, Brackhan M, Krohn M, Mairinger S, Filip T, Sauberer M, Stanek J, Pekar T, Pahnke J, Langer O. Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model. International Journal of Molecular Sciences. 21. PMID 33153231 DOI: 10.3390/ijms21218245  0.327
2020 Borovkova M, Bykov A, Popov A, Pierangelo A, Novikova T, Pahnke J, Meglinski I. Evaluating β-amyloidosis progression in Alzheimer's disease with Mueller polarimetry. Biomedical Optics Express. 11: 4509-4519. PMID 32923060 DOI: 10.1364/BOE.396294  0.309
2018 Storck SE, Hartz AMS, Bernard J, Wolf A, Kachlmeier A, Mahringer A, Weggen S, Pahnke J, Pietrzik CU. The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM. Brain, Behavior, and Immunity. PMID 30041013 DOI: 10.1016/J.Bbi.2018.07.017  0.34
2018 Lamartinière Y, Boucau MC, Dehouck L, Krohn M, Pahnke J, Candela P, Gosselet F, Fenart L. ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier. Journal of Alzheimer's Disease : Jad. PMID 30010117 DOI: 10.3233/JAD-170883  0.316
2017 Steffen J, Krohn M, Schwitlick C, Brüning T, Paarmann K, Pietrzik CU, Biverstål H, Jansone B, Langer O, Pahnke J. Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice. Acta Neuropathologica Communications. 5: 49. PMID 28637503 DOI: 10.1186/S40478-017-0448-2  0.327
2015 Krohn M, Bracke A, Avchalumov Y, Schumacher T, Hofrichter J, Paarmann K, Fröhlich C, Lange C, Brüning T, von Bohlen Und Halbach O, Pahnke J. Accumulation of murine amyloid-β mimics early Alzheimer's disease. Brain : a Journal of Neurology. 138: 2370-82. PMID 25991605 DOI: 10.1093/brain/awv137  0.31
2014 Pahnke J, Langer O, Krohn M. Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment. Neurobiology of Disease. 72: 54-60. PMID 24746857 DOI: 10.1016/J.Nbd.2014.04.001  0.43
2013 Hofrichter J, Krohn M, Schumacher T, Lange C, Feistel B, Walbroel B, Heinze HJ, Crockett S, Sharbel TF, Pahnke J. Reduced Alzheimer's disease pathology by St. John's Wort treatment is independent of hyperforin and facilitated by ABCC1 and microglia activation in mice. Current Alzheimer Research. 10: 1057-69. PMID 24156265 DOI: 10.2174/15672050113106660171  0.308
2013 Pahnke J, Fröhlich C, Krohn M, Schumacher T, Paarmann K. Impaired mitochondrial energy production and ABC transporter function-A crucial interconnection in dementing proteopathies of the brain. Mechanisms of Ageing and Development. 134: 506-15. PMID 24012632 DOI: 10.1016/J.Mad.2013.08.007  0.395
2013 Fröhlich C, Paarmann K, Steffen J, Stenzel J, Krohn M, Heinze HJ, Pahnke J. Genomic background-related activation of microglia and reduced β-amyloidosis in a mouse model of Alzheimer's disease. European Journal of Microbiology & Immunology. 3: 21-27. PMID 23814667 DOI: 10.1556/Eujmi.3.2013.1.3  0.324
2012 Schumacher T, Krohn M, Hofrichter J, Lange C, Stenzel J, Steffen J, Dunkelmann T, Paarmann K, Fröhlich C, Uecker A, Plath AS, Sommer A, Brüning T, Heinze HJ, Pahnke J. ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice. Plos One. 7: e35613. PMID 22545122 DOI: 10.1371/Journal.Pone.0035613  0.37
2012 Scheffler K, Krohn M, Dunkelmann T, Stenzel J, Miroux B, Ibrahim S, von Bohlen Und Halbach O, Heinze HJ, Walker LC, Gsponer JA, Pahnke J. Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis. Acta Neuropathologica. 124: 199-208. PMID 22526016 DOI: 10.1007/S00401-012-0980-X  0.472
2012 Schmidt A, Pahnke J. Efficient near-infrared in vivo imaging of amyoid-β deposits in Alzheimer's disease mouse models. Journal of Alzheimer's Disease : Jad. 30: 651-64. PMID 22460331 DOI: 10.3233/JAD-2012-112168  0.335
2011 Krohn M, Lange C, Hofrichter J, Scheffler K, Stenzel J, Steffen J, Schumacher T, Brüning T, Plath AS, Alfen F, Schmidt A, Winter F, Rateitschak K, Wree A, Gsponer J, ... ... Pahnke J, et al. Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice. The Journal of Clinical Investigation. 121: 3924-31. PMID 21881209 DOI: 10.1172/Jci57867  0.556
2011 Teipel SJ, Buchert R, Thome J, Hampel H, Pahnke J. Development of Alzheimer-disease neuroimaging-biomarkers using mouse models with amyloid-precursor protein-transgene expression. Progress in Neurobiology. 95: 547-56. PMID 21601614 DOI: 10.1016/J.Pneurobio.2011.05.004  0.4
2011 Scheffler K, Stenzel J, Krohn M, Lange C, Hofrichter J, Schumacher T, Brüning T, Plath AS, Walker L, Pahnke J. Determination of spatial and temporal distribution of microglia by 230nm-high-resolution, high-throughput automated analysis reveals different amyloid plaque populations in an APP/PS1 mouse model of Alzheimer's disease. Current Alzheimer Research. 8: 781-8. PMID 21244350 DOI: 10.2174/156720511797633179  0.586
2011 Teipel SJ, Kaza E, Hadlich S, Bauer A, Brüning T, Plath AS, Krohn M, Scheffler K, Walker LC, Lotze M, Pahnke J. Automated detection of amyloid-β-related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI. Journal of Alzheimer's Disease : Jad. 23: 221-37. PMID 20966552 DOI: 10.3233/Jad-2010-101035  0.561
2009 Pahnke J, Krohn M, Scheffler K. [The role of blood-brain barrier in the pathogenesis of Alzheimer dementia--implications for immunological therapies for plaque dissolution]. Fortschritte Der Neurologie-Psychiatrie. 77: S21-4. PMID 19685385 DOI: 10.1055/S-0028-1109601  0.435
2009 Pahnke J, Walker LC, Scheffler K, Krohn M. Alzheimer's disease and blood-brain barrier function-Why have anti-beta-amyloid therapies failed to prevent dementia progression? Neuroscience and Biobehavioral Reviews. 33: 1099-108. PMID 19481107 DOI: 10.1016/J.Neubiorev.2009.05.006  0.583
2008 Pahnke J, Wolkenhauer O, Krohn M, Walker LC. Clinico-pathologic function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's disease. Current Alzheimer Research. 5: 396-405. PMID 18690837 DOI: 10.2174/156720508785132262  0.553
2007 Marx FP, Soehn AS, Berg D, Melle C, Schiesling C, Lang M, Kautzmann S, Strauss KM, Franck T, Engelender S, Pahnke J, Dawson S, von Eggeling F, Schulz JB, Riess O, et al. The proteasomal subunit S6 ATPase is a novel synphilin-1 interacting protein--implications for Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1759-67. PMID 17327361 DOI: 10.1096/Fj.06-6734Com  0.313
2007 Hoffrogge R, Beyer S, Hübner R, Mikkat S, Mix E, Scharf C, Schmitz U, Pauleweit S, Berth M, Zubrzycki IZ, Christoph H, Pahnke J, Wolkenhauer O, Uhrmacher A, Völker U, et al. 2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells. Proteomics. 7: 33-46. PMID 17146836 DOI: 10.1002/Pmic.200600614  0.309
2006 Mix E, Ibrahim SM, Pahnke J, Glass A, Mazón-Peláez I, Lemcke S, Koczan D, Gimsa U, Bansemer S, Scheel T, Karopka T, Böttcher T, Müller J, Dazert E, Antipova V, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor Atorvastatin mediated effects depend on the activation status of target cells in PLP-EAE. Journal of Autoimmunity. 27: 251-65. PMID 17085013 DOI: 10.1016/J.Jaut.2006.09.006  0.314
2006 Vogler S, Pahnke J, Rousset S, Ricquier D, Moch H, Miroux B, Ibrahim SM. Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis. The American Journal of Pathology. 168: 1570-5. PMID 16651623 DOI: 10.2353/Ajpath.2006.051069  0.311
2004 Vogelgesang S, Warzok RW, Cascorbi I, Kunert-Keil C, Schroeder E, Kroemer HK, Siegmund W, Walker LC, Pahnke J. The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease. Current Alzheimer Research. 1: 121-5. PMID 15975076 DOI: 10.2174/1567205043332225  0.583
2004 Vogelgesang S, Kunert-Keil C, Cascorbi I, Mosyagin I, Schröder E, Runge U, Jedlitschky G, Kroemer HK, Oertel J, Gaab MR, Pahnke J, Walker LC, Warzok RW. Expression of multidrug transporters in dysembryoplastic neuroepithelial tumors causing intractable epilepsy. Clinical Neuropathology. 23: 223-31. PMID 15581025  0.476
2004 Peters S, Mix E, Bauer P, Weinelt S, Schubert B, Knoblich R, Böttcher T, Strauss U, Pahnke J, Cattaneo E, Wree A, Rolfs A. Wnt-5a expression in the rat neuronal progenitor cell line ST14A. Experimental Brain Research. 158: 189-95. PMID 15309358 DOI: 10.1007/S00221-004-1887-0  0.317
2004 Pahnke J, Mix E, Knoblich R, Müller J, Zschiesche M, Schubert B, Koczan D, Bauer P, Böttcher T, Thiesen HJ, Lazarov L, Wree A, Rolfs A. Overexpression of glial cell line-derived neurotrophic factor induces genes regulating migration and differentiation of neuronal progenitor cells. Experimental Cell Research. 297: 484-94. PMID 15212950 DOI: 10.1016/S0344-0338(04)80448-5  0.307
2004 Mix E, Ibrahim S, Pahnke J, Koczan D, Sina C, Böttcher T, Thiesen HJ, Rolfs A. Gene-expression profiling of the early stages of MOG-induced EAE proves EAE-resistance as an active process. Journal of Neuroimmunology. 151: 158-70. PMID 15145614 DOI: 10.1016/J.Jneuroim.2004.03.007  0.306
2003 Böttcher T, Mix E, Koczan D, Bauer P, Pahnke J, Peters S, Weinelt S, Knoblich R, Strauss U, Cattaneo E, Thiesen HJ, Rolfs A. Gene expression profiling of ciliary neurotrophic factor-overexpressing rat striatal progenitor cells (ST14A) indicates improved stress response during the early stage of differentiation. Journal of Neuroscience Research. 73: 42-53. PMID 12815707 DOI: 10.1002/Jnr.10624  0.321
2003 Pahnke J, Walker LC, Schroeder E, Vogelgesang S, Stausske D, Walther R, Warzok RW. Cerebral beta-amyloid deposition is augmented by the -491AA promoter polymorphism in non-demented elderly individuals bearing the apolipoprotein E epsilon4 allele. Acta Neuropathologica. 105: 25-9. PMID 12471457 DOI: 10.1007/s00401-002-0602-0  0.542
2002 Vogelgesang S, Cascorbi I, Schroeder E, Pahnke J, Kroemer HK, Siegmund W, Kunert-Keil C, Walker LC, Warzok RW. Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans. Pharmacogenetics. 12: 535-41. PMID 12360104 DOI: 10.1097/00008571-200210000-00005  0.594
2002 Vogelgesang S, Schroeder E, Walker LC, Pahnke J, Naubereit A, Walther R, Stausske D, Warzok RW. Activated microglia do not mediate the early deposition of Abeta in carriers of the apolipoprotein Eepsilon4 allele. Clinical Neuropathology. 21: 99-106. PMID 12049183  0.535
2000 Walker LC, Pahnke J, Madauss M, Vogelgesang S, Pahnke A, Herbst EW, Stausske D, Walther R, Kessler C, Warzok RW. Apolipoprotein E4 promotes the early deposition of Abeta42 and then Abeta40 in the elderly. Acta Neuropathologica. 100: 36-42. PMID 10912918 DOI: 10.1007/S004010051190  0.528
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