Choel W. Kim, Ph.D. - Publications

Affiliations: 
2002 University of California, San Diego, La Jolla, CA 
Area:
Molecular Biology, Microbiology Biology, Biochemistry

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sharma R, Kim JJ, Qin L, Henning P, Akimoto M, VanSchouwen B, Kaur G, Sankaran B, MacKenzie KR, Melacini G, Casteel DE, Herberg FW, Kim CW. An auto-inhibited state of protein kinase G and implications for selective activation. Elife. 11. PMID 35929723 DOI: 10.7554/eLife.79530  0.397
2021 Huang J, Byun JA, VanSchouwen B, Henning P, Herberg FW, Kim C, Melacini G. Dynamical Basis of Allosteric Activation for the Protein Kinase G. The Journal of Physical Chemistry. B. PMID 34115498 DOI: 10.1021/acs.jpcb.1c03622  0.345
2020 Kim C, Sharma R. Cyclic nucleotide selectivity of PKG isozymes. Protein Science : a Publication of the Protein Society. PMID 33271627 DOI: 10.1002/pro.4008  0.351
2020 Chan MH, Aminzai S, Hu T, Taran A, Li S, Kim C, Pilz RB, Casteel DE. A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP. The Journal of Biological Chemistry. PMID 32506052 DOI: 10.1074/Jbc.Ra119.010984  0.434
2020 Byun JA, Van K, Huang J, Henning P, Franz E, Akimoto M, Herberg FW, Kim C, Melacini G. Mechanism of allosteric inhibition in the cGMP-dependent protein kinase. The Journal of Biological Chemistry. PMID 32317283 DOI: 10.1074/Jbc.Ra120.013070  0.424
2019 El Bakkouri M, Kouidmi I, Wernimont AK, Amani M, Hutchinson A, Loppnau P, Kim JJ, Flueck C, Walker JR, Seitova A, Senisterra G, Kakihara Y, Kim C, Blackman MJ, Calmettes C, et al. Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31239348 DOI: 10.1073/Pnas.1905558116  0.524
2018 Qin L, Sankaran B, Aminzai S, Casteel D, Kim C. Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46. The Journal of Biological Chemistry. PMID 29769318 DOI: 10.1074/Jbc.Ra118.002427  0.43
2018 Gerlits OO, Campbell JC, Blakeley MP, Kim C, Kovalevsky AY. Neutron crystallography detects differences in protein dynamics: Structure of PKG II cyclic nucleotide binding domain in complex with an activator. Biochemistry. PMID 29517905 DOI: 10.1021/Acs.Biochem.8B00010  0.447
2017 He D, Lorenz R, Kim C, Herberg FW, Lim CJ. Switching cyclic nucleotide-selective activation of PKA holoenzyme reveals distinct roles of tandem CNB domains. Acs Chemical Biology. PMID 29111666 DOI: 10.1021/Acschembio.7B00732  0.489
2017 Campbell JC, Henning P, Franz E, Sankaran B, Herberg FW, Kim C. Structural Basis of Analog Specificity in PKG I and II. Acs Chemical Biology. PMID 28793191 DOI: 10.1021/Acschembio.7B00369  0.452
2017 Lorenz R, Moon EW, Kim JJ, Schmidt SH, Sankaran B, Pavlidis IV, Kim C, Herberg FW. Mutations of PKA cyclic nucleotide binding domains reveal novel aspects of cyclic nucleotide selectivity. The Biochemical Journal. PMID 28583991 DOI: 10.1042/Bcj20160969  0.511
2016 Campbell JC, VanSchouwen B, Lorenz R, Sankaran B, Herberg FW, Melacini G, Kim C. Crystal structure of PKG Iβ CNB-B:Rp-cGMPS complex reveals an apo-like, inactive conformation. Febs Letters. PMID 27914169 DOI: 10.1002/1873-3468.12505  0.529
2016 Campbell JC, Tischer A, Machha V, Moon-Tasson L, Sankaran B, Kim C, Auton M. Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p.Gly1324Ser) of the von Willebrand factor A1 domain. Data in Brief. 7: 1700-1706. PMID 27761512 DOI: 10.1016/J.Dib.2016.05.004  0.354
2016 Kim JJ, Lorenz R, Arold ST, Reger AS, Sankaran B, Casteel DE, Herberg FW, Kim C. Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation. Structure (London, England : 1993). PMID 27066748 DOI: 10.1016/J.Str.2016.03.009  0.514
2016 Campbell JC, Kim JJ, Li KY, Huang GY, Reger AS, Matsuda S, Sankaran B, Link TM, Yuasa K, Ladbury JE, Casteel DE, Kim C. Structural Basis of Cyclic Nucleotide Selectivity in cGMP-Dependent Protein Kinase II. The Journal of Biological Chemistry. PMID 26769964 DOI: 10.1186/2050-6511-16-S1-A15  0.482
2016 Kim JJ, Lorenz R, Arold ST, Reger RS, Sankaran B, Casteel DE, Herberg FW, Kim C. Structural Analysis of the PKG I Regulatory Domain Reveals a Novel cGMP-Induced Dimeric Interface that Promotes Activation. Structure. DOI: 10.2210/Pdb4Z07/Pdb  0.391
2015 Tischer A, Campbell JC, Machha VR, Moon-Tasson L, Benson LM, Sankaran B, Kim C, Auton M. Mutational constraints on local unfolding inhibit the rheological adaptation of von Willebrand factor. The Journal of Biological Chemistry. PMID 26677223 DOI: 10.1074/Jbc.M115.703850  0.345
2015 VanSchouwen B, Selvaratnam R, Giri R, Lorenz R, Herberg FW, Kim C, Melacini G. Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG). The Journal of Biological Chemistry. PMID 26370085 DOI: 10.1074/Jbc.M115.685305  0.48
2015 Qin L, Reger AS, Guo E, Yang MP, Zwart P, Casteel DE, Kim C. Structures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability. Biochemistry. 54: 4419-22. PMID 26132214 DOI: 10.1021/Acs.Biochem.5B00572  0.422
2015 Kim JJ, Flueck C, Franz E, Sanabria-Figueroa E, Thompson E, Lorenz R, Bertinetti D, Baker DA, Herberg FW, Kim C. Crystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egress. Plos Pathogens. 11: e1004639. PMID 25646845 DOI: 10.1371/Journal.Ppat.1004639  0.517
2015 Lorenz R, He D, Kim C, Lim CJ, Herberg FW. Rational design of a PKA-based sensor for cGMP Bmc Pharmacology and Toxicology. 16. DOI: 10.1186/2050-6511-16-S1-A64  0.438
2015 Franz E, Kim JJ, Schneider O, Bertinetti D, Kim C, Herberg FW. The role of a parasite-specific D-site in activation of Plasmodium falciparum cGMP-dependent protein kinase. Bmc Clinical Pharmacology. 16: 1-2. DOI: 10.1186/2050-6511-16-S1-A51  0.375
2014 Huang GY, Gerlits OO, Blakeley MP, Sankaran B, Kovalevsky AY, Kim C. Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: insights for cGMP-dependent protein kinase agonist design. Biochemistry. 53: 6725-7. PMID 25271401 DOI: 10.1021/Bi501012V  0.453
2014 Reger AS, Yang MP, Koide-Yoshida S, Guo E, Mehta S, Yuasa K, Liu A, Casteel DE, Kim C. Crystal structure of the cGMP-dependent protein kinase II leucine zipper and Rab11b protein complex reveals molecular details of G-kinase-specific interactions. The Journal of Biological Chemistry. 289: 25393-403. PMID 25070890 DOI: 10.1074/Jbc.M114.575894  0.436
2014 Huang GY, Kim JJ, Reger AS, Lorenz R, Moon EW, Zhao C, Casteel DE, Bertinetti D, Vanschouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG i Structure. 22: 116-124. PMID 24239458 DOI: 10.1016/J.Str.2013.09.021  0.531
2014 Campbell J, Huang G, Reger A, Link T, Ladbury J, Kim C. Insights into the Cyclic Nucleotide Selectivity Mechanism of Cyclic GMP Dependent Protein Kinase II Biophysical Journal. 106: 658a. DOI: 10.1016/J.Bpj.2013.11.3644  0.456
2013 Guo DC, Regalado E, Casteel DE, Santos-Cortez RL, Gong L, Kim JJ, Dyack S, Horne SG, Chang G, Jondeau G, Boileau C, Coselli JS, Li Z, Leal SM, Shendure J, ... ... Kim C, et al. Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections. American Journal of Human Genetics. 93: 398-404. PMID 23910461 DOI: 10.1016/J.Ajhg.2013.06.019  0.309
2013 Lorenz R, Moon E, Huang GY, Reger AS, Kim JJ, Franz E, Bertinetti D, Kim C, Herberg FW. Transforming PKA into PKG – a structure-function approach to understand cyclic nucleotide selectivity Bmc Pharmacology and Toxicology. 14. DOI: 10.1186/2050-6511-14-S1-P41  0.503
2013 Kim JJ, Figueroa ES, Franz E, Bertinetti D, Herberg F, Kim C. Crystal structures of the carboxyl cGMP binding domain of plasmodium falciparum cGMP-dependent protein kinase reveals a novel salt bridge crucial for activation Bmc Clinical Pharmacology. 14: 33. DOI: 10.1186/2050-6511-14-S1-P33  0.484
2013 Huang GY, Kim JJ, Reger AS, Lorenz R, Moon E, Zhao C, Casteel DE, Bertinetti D, VanSchouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Structures of human PKG reveal cGMP-selectived activation mechanisms Bmc Pharmacology and Toxicology. 14. DOI: 10.1186/2050-6511-14-S1-O16  0.443
2012 Grimster NP, Stump B, Fotsing JR, Weide T, Talley TT, Yamauchi JG, Nemecz Á, Kim C, Ho KY, Sharpless KB, Taylor P, Fokin VV. Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template. Journal of the American Chemical Society. 134: 6732-40. PMID 22394239 DOI: 10.1021/Ja3001858  0.397
2011 Kryshtafovych A, Moult J, Bartual SG, Bazan JF, Berman H, Casteel DE, Christodoulou E, Everett JK, Hausmann J, Heidebrecht T, Hills T, Hui R, Hunt JF, Seetharaman J, Joachimiak A, ... ... Kim C, et al. Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction. Proteins. 79: 6-20. PMID 22020785 DOI: 10.1002/Prot.23196  0.422
2011 Lee JH, Li S, Liu T, Hsu S, Kim C, Woods VL, Casteel DE. The amino terminus of cGMP-dependent protein kinase Iβ increases the dynamics of the protein's cGMP-binding pockets. International Journal of Mass Spectrometry. 302: 44-52. PMID 21643460 DOI: 10.1016/J.Ijms.2010.07.021  0.468
2011 Kim JJ, Casteel DE, Huang G, Kwon TH, Ren RK, Zwart P, Headd JJ, Brown NG, Chow DC, Palzkill T, Kim C. Co-crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding. Plos One. 6: e18413. PMID 21526164 DOI: 10.1371/Journal.Pone.0018413  0.428
2011 Boettcher AJ, Wu J, Kim C, Yang J, Bruystens J, Cheung N, Pennypacker JK, Blumenthal DA, Kornev AP, Taylor SS. Realizing the allosteric potential of the tetrameric protein kinase A RIα holoenzyme. Structure (London, England : 1993). 19: 265-76. PMID 21300294 DOI: 10.1016/J.Str.2010.12.005  0.468
2011 Badireddy S, Yunfeng G, Ritchie M, Akamine P, Wu J, Kim CW, Taylor SS, Qingsong L, Swaminathan K, Anand GS. Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design. Molecular & Cellular Proteomics : McP. 10: M110.004390. PMID 21081668 DOI: 10.1074/Mcp.M110.004390  0.708
2011 Kim JJ, Casteel DE, Huang G, Kwon TH, Ren RK, Zwart P, Headd JJ, Brown NG, Chow D, Palzkill T, Kim C. The crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding Bmc Pharmacology. 11: 1-3. DOI: 10.1186/1471-2210-11-S1-O14  0.428
2010 Casteel DE, Smith-Nguyen EV, Sankaran B, Roh SH, Pilz RB, Kim C. A crystal structure of the cyclic GMP-dependent protein kinase I{beta} dimerization/docking domain reveals molecular details of isoform-specific anchoring. The Journal of Biological Chemistry. 285: 32684-8. PMID 20826808 DOI: 10.1074/Jbc.C110.161430  0.49
2010 Sarma GN, Kinderman FS, Kim C, von Daake S, Chen L, Wang BC, Taylor SS. Structure of D-AKAP2:PKA RI complex: insights into AKAP specificity and selectivity. Structure (London, England : 1993). 18: 155-66. PMID 20159461 DOI: 10.1016/J.Str.2009.12.012  0.405
2009 Brown SH, Wu J, Kim C, Alberto K, Taylor SS. Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures. Journal of Molecular Biology. 393: 1070-82. PMID 19748511 DOI: 10.1016/J.Jmb.2009.09.014  0.525
2009 Thompson EE, Kornev AP, Kannan N, Kim C, Ten Eyck LF, Taylor SS. Comparative surface geometry of the protein kinase family. Protein Science : a Publication of the Protein Society. 18: 2016-26. PMID 19610074 DOI: 10.1002/Pro.209  0.427
2009 Boettcher AJ, Wu J, Kim C, Yang J, Bruystens J, Cheung N, Pennypacker JK, Blumenthal DA, Kornev AP, Taylor SS. Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase Structure. 19: 265-276. DOI: 10.2210/Pdb3Pvb/Pdb  0.429
2009 Casteel DE, Smith-Nguyen EV, Sankaran B, Spraggon G, Hampton EN, Pilz RB, Taylor SS, Kim C. The first crystal structure of cyclic GMP-dependent protein kinase Iβ dimerization/docking domain reveals molecular details of isoform-specific anchoring Bmc Pharmacology. 9: P6. DOI: 10.1186/1471-2210-9-S1-P6  0.483
2008 Taylor SS, Kim C, Cheng CY, Brown SH, Wu J, Kannan N. Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design. Biochimica Et Biophysica Acta. 1784: 16-26. PMID 17996741 DOI: 10.1016/J.Bbapap.2007.10.002  0.522
2007 Kim C, Cheng CY, Saldanha SA, Taylor SS. PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell. 130: 1032-43. PMID 17889648 DOI: 10.1016/J.Cell.2007.07.018  0.536
2006 Kinderman FS, Kim C, von Daake S, Ma Y, Pham BQ, Spraggon G, Xuong NH, Jennings PA, Taylor SS. A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. Molecular Cell. 24: 397-408. PMID 17081990 DOI: 10.1016/J.Molcel.2006.09.015  0.626
2006 Kim C, Vigil D, Anand G, Taylor SS. Structure and dynamics of PKA signaling proteins. European Journal of Cell Biology. 85: 651-4. PMID 16647784 DOI: 10.1016/J.Ejcb.2006.02.004  0.333
2006 Gullingsrud J, Kim C, Taylor SS, McCammon JA. Dynamic binding of PKA regulatory subunit RIα Structure. 14: 141-149. PMID 16407073 DOI: 10.1016/J.Str.2005.09.019  0.472
2005 Taylor SS, Kim C, Vigil D, Haste NM, Yang J, Wu J, Anand GS. Dynamics of signaling by PKA. Biochimica Et Biophysica Acta. 1754: 25-37. PMID 16214430 DOI: 10.1016/J.Bbapap.2005.08.024  0.5
2005 Kim C, Xuong NH, Taylor SS. Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA. Science (New York, N.Y.). 307: 690-6. PMID 15692043 DOI: 10.1126/Science.1104607  0.664
2002 Taylor SS, Kim CW, Cheng CY, Kannan N, Sastri M, Eggers CW, Wu J. Fifty Years Since the Discovery of PKA. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4123. PMID 29430987 DOI: 10.1096/Fasebj.22.1_Supplement.412.3  0.466
2002 Kim C, Xuong NH, Edwards S, Madhusudan, Yee MC, Spraggon G, Mills SE. The crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum. Febs Letters. 523: 239-46. PMID 12123839 DOI: 10.1016/S0014-5793(02)02905-8  0.577
2001 Spraggon G, Kim C, Nguyen-Huu X, Yee MC, Yanofsky C, Mills SE. The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan. Proceedings of the National Academy of Sciences of the United States of America. 98: 6021-6. PMID 11371633 DOI: 10.1073/Pnas.111150298  0.44
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