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Darci J. Trader - Publications

Affiliations: 
The Scripps Research Institute, Scripps Florida 
 2016- Purdue University, West Lafayette, IN, United States 
Area:
Organic Synthesis, Chemical Biology
Website:
http://www.mcmp.purdue.edu/directory/?uid=dtrader
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nelson S, Harris TJ, Muli CS, Maresh ME, Baker B, Smith C, Neumann C, Trader DJ, Parkinson EI. Discovery and Development of Cyclic Peptide Proteasome Stimulators. Chembiochem : a European Journal of Chemical Biology. e202300671. PMID 38055197 DOI: 10.1002/cbic.202300671  0.314
2022 Halder S, Macatangay NJ, Zerfas BL, Salazar-Chaparro AF, Trader DJ. Oleic amide derivatives as small molecule stimulators of the human proteasome's core particle. Rsc Medicinal Chemistry. 13: 1077-1081. PMID 36324496 DOI: 10.1039/d2md00133k  0.711
2022 Salazar-Chaparro AF, Halder S, Trader DJ. Synthesis and Application of a Clickable Epoxomicin-Based Probe for Proteasome Activity Analysis. Current Protocols. 2: e490. PMID 35849029 DOI: 10.1002/cpz1.490  0.71
2022 Salazar-Chaparro AF, Halder S, Maresh ME, Trader DJ. Solid-Phase Synthesis and Application of a Clickable Version of Epoxomicin for Proteasome Activity Analysis. Chembiochem : a European Journal of Chemical Biology. e202100710. PMID 35107861 DOI: 10.1002/cbic.202100710  0.715
2021 Tian W, Maresh ME, Trader DJ. Approaches to Evaluate the Impact of a Small-Molecule Binder to a Noncatalytic Site of the Proteasome. Chembiochem : a European Journal of Chemical Biology. PMID 33617657 DOI: 10.1002/cbic.202100023  0.329
2020 Maresh ME, Salazar-Chaparro AF, Trader DJ. Methods for the discovery of small molecules to monitor and perturb the activity of the human proteasome. Future Medicinal Chemistry. PMID 33275045 DOI: 10.4155/fmc-2020-0288  0.336
2020 Zerfas BL, Coleman RA, Salazar-Chaparro AF, Macatangay NJ, Trader DJ. Fluorescent Probes with Unnatural Amino Acids to Monitor Proteasome Activity in Real-Time. Acs Chemical Biology. PMID 32786259 DOI: 10.1021/Acschembio.0C00634  0.452
2020 Borsari C, Trader DJ, Tait A, Costi MP. Designing Chimeric Molecules for Drug Discovery by Leveraging Chemical Biology. Journal of Medicinal Chemistry. PMID 32023055 DOI: 10.1021/Acs.Jmedchem.9B01456  0.398
2020 Trader DJ, Zerfas B. Advanced Activity‐Based Probes to Monitor the Proteasome in Live Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09065  0.317
2019 Tian W, Trader DJ. Discovery of a Small Molecule Probe to Rpn-6, an Essential Subunit of the 26S Proteasome. Acs Chemical Biology. PMID 31877015 DOI: 10.1021/Acschembio.9B01019  0.433
2019 Zerfas BL, Trader DJ. Synthesis and Application of an Activity-Based Peptide-Peptoid Hybrid Probe for the Immunoproteasome. Current Protocols in Chemical Biology. 11: e76. PMID 31860787 DOI: 10.1002/Cpch.76  0.465
2019 Zerfas BL, Maresh ME, Trader DJ. The Immunoproteasome: An Emerging Target in Cancer, Autoimmune and Neurological Disorders. Journal of Medicinal Chemistry. PMID 31670954 DOI: 10.1021/Acs.Jmedchem.9B01226  0.366
2019 Coleman RA, Trader DJ. Methods to Discover and Evaluate Proteasome Small Molecule Stimulators. Molecules (Basel, Switzerland). 24. PMID 31242677 DOI: 10.3390/Molecules24122341  0.41
2019 Zerfas BL, Trader DJ. Monitoring the Immunoproteasome in Live Cells Using an Activity-Based Peptide-Peptoid Hybrid Probe. Journal of the American Chemical Society. PMID 30862160 DOI: 10.1021/Jacs.8B12873  0.439
2019 Muli C, Tian W, Trader DJ. Small Molecule Inhibitors of the Proteasome's Regulatory Particle. Chembiochem : a European Journal of Chemical Biology. PMID 30740849 DOI: 10.1002/Cbic.201900017  0.41
2019 Maresh ME, Trader DJ. Development of a Method to Prioritize Protein-Ligand Pairs on Beads Using Protein Conjugated to a Near-IR Dye. Acs Combinatorial Science. PMID 30677288 DOI: 10.1021/Acscombsci.8B00165  0.366
2018 Coleman RA, Muli CS, Zhao Y, Bhardwaj A, Newhouse TR, Trader DJ. Analysis of chain length, substitution patterns, and unsaturation of AM-404 derivatives as 20S proteasome stimulators. Bioorganic & Medicinal Chemistry Letters. PMID 30587447 DOI: 10.1016/J.Bmcl.2018.12.030  0.415
2018 Coleman RA, Trader DJ. A Sensitive High-Throughput Screening Method for Identifying Small Molecule Stimulators of the Core Particle of the Proteasome. Current Protocols in Chemical Biology. e52. PMID 30285317 DOI: 10.1002/Cpch.52  0.427
2018 Coleman R, Trader DJ. Development and Application of a Sensitive Peptide Reporter to Discover 20S Proteasome Stimulators. Acs Combinatorial Science. PMID 29553711 DOI: 10.1021/Acscombsci.7B00193  0.385
2017 Trader DJ, Simanski S, Dickson P, Kodadek T. Establishment of a suite of assays that support the discovery of proteasome stimulators. Biochimica Et Biophysica Acta. 1861: 892-899. PMID 28065760 DOI: 10.1016/J.Bbagen.2017.01.003  0.568
2015 Trader DJ, Carlson EE. Chemoselective enrichment as a tool to increase access to bioactive natural products: Case study borrelidin. Bioorganic & Medicinal Chemistry Letters. 25: 4767-9. PMID 26255540 DOI: 10.1016/J.Bmcl.2015.07.062  0.638
2015 Trader DJ, Simanski S, Kodadek T. A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells. Journal of the American Chemical Society. 137: 6312-9. PMID 25914958 DOI: 10.1021/Jacs.5B02069  0.556
2015 Trader DJ, Carlson EE. Chemoselective enrichment as a tool to increase access to bioactive natural products: Case study borrelidin Bioorganic and Medicinal Chemistry Letters. DOI: 10.1016/j.bmcl.2015.07.062  0.539
2014 Trader DJ, Carlson EE. Toward the development of solid-supported reagents for separation of alcohol-containing compounds by steric environment Tetrahedron. 70: 4191-4196. DOI: 10.1016/J.Tet.2014.03.040  0.617
2013 Trader DJ, Carlson EE. Taming of a superbase for selective phenol desilylation and natural product isolation. The Journal of Organic Chemistry. 78: 7349-55. PMID 23815363 DOI: 10.1021/Jo4010298  0.623
2013 Sidebottom AM, Johnson AR, Karty JA, Trader DJ, Carlson EE. Integrated metabolomics approach facilitates discovery of an unpredicted natural product suite from Streptomyces coelicolor M145. Acs Chemical Biology. 8: 2009-16. PMID 23777274 DOI: 10.1021/Cb4002798  0.718
2012 Trader DJ, Carlson EE. Chemoselective hydroxyl group transformation: an elusive target. Molecular Biosystems. 8: 2484-93. PMID 22695722 DOI: 10.1039/C2Mb25122A  0.618
2011 Odendaal AY, Trader DJ, Carlson EE. Chemoselective enrichment for natural products discovery. Chemical Science. 2: 760-764. PMID 24926410 DOI: 10.1039/C0Sc00620C  0.679
2011 Trader DJ, Carlson EE. Siloxyl ether functionalized resins for chemoselective enrichment of carboxylic acids. Organic Letters. 13: 5652-5. PMID 21957886 DOI: 10.1021/Ol202376M  0.647
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