Frederico Guilherme Graeff - Publications

Affiliations: 
Faculdade de Medicina de Ribeirão Preto University of São Paulo, São Paulo, São Paulo, Brazil 
Area:
Panic disorder, Psychobiology, Behavioral pharmacology

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Maraschin JC, Sestile CC, Yabiku CT, Roncon CM, Fiaes GCdS, Graeff FG, Audi EA, Zangrossi H. Effects of the adjunctive treatment of antidepressants with opiorphin on a panic-like defensive response in rats. Behavioural Brain Research. 378: 112263. PMID 31568834 DOI: 10.1016/J.Bbr.2019.112263  0.388
2017 Sestile CC, Maraschin JC, Rangel MP, Santana RG, Zangrossi H, Graeff FG, Audi EA. B2-kinin receptors in the dorsal periaqueductal gray are implicated in the panicolytic-like effect of opiorphin. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 79: 493-498. PMID 28797641 DOI: 10.1016/J.Pnpbp.2017.08.003  0.412
2017 Shuhama R, Blanchard DC, Graeff FG, Del-Ben CM. What we imagine is what we do? A critical overview about mental imagery as a strategy to study human defensive responses. Behavioural Brain Research. 18-28. PMID 28716675 DOI: 10.1016/J.Bbr.2017.07.012  0.482
2017 Roncon CM, Yamashita PSM, Frias AT, Audi EA, Graeff FG, Coimbra NC, Zangrossi H. μ-Opioid and 5-HT1A receptors in the dorsomedial hypothalamus interact for the regulation of panic-related defensive responses. Journal of Psychopharmacology (Oxford, England). 31: 715-721. PMID 28583050 DOI: 10.1177/0269881117693747  0.358
2017 Sestile CC, Maraschin JC, Gama VS, Zangrossi H, Graeff FG, Audi EA. Panicolytic-like action of bradykinin in the dorsal periaqueductal gray through μ-opioid and B2-kinin receptors Neuropharmacology. 123: 80-87. PMID 28554847 DOI: 10.1016/J.Neuropharm.2017.05.025  0.375
2017 Maraschin JC, Almeida CB, Rangel MP, Roncon CM, Sestile CC, Zangrossi H, Graeff FG, Audi EA. Participation of dorsal periaqueductal gray 5-HT1A receptors in the panicolytic-like effect of the κ-opioid receptor antagonist Nor-BNI. Behavioural Brain Research. 327: 75-82. PMID 28347824 DOI: 10.1016/J.Bbr.2017.03.033  0.423
2017 Graeff FG. Translational approach to the pathophysiology of panic disorder: Focus on serotonin and endogenous opioids. Neuroscience and Biobehavioral Reviews. PMID 28073587 DOI: 10.1016/J.Neubiorev.2016.10.013  0.348
2016 Shuhama R, Rondinoni C, de Araujo DB, de Freitas Caetano G, Dos Santos AC, Graeff FG, Del-Ben CM. Behavioral and Neuroimaging Responses Induced by Mental Imagery of Threatening Scenarios. Behavioural Brain Research. PMID 27452804 DOI: 10.1016/J.Bbr.2016.06.059  0.338
2015 Maraschin JC, Rangel MP, Bonfim AJ, Kitayama M, Graeff FG, Zangrossi H, Audi EA. Opiorphin causes a panicolytic-like effect in rat panic models mediated by μ-opioid receptors in the dorsal periaqueductal gray. Neuropharmacology. 101: 264-270. PMID 26363194 DOI: 10.1016/J.Neuropharm.2015.09.008  0.385
2015 Graeff FG, Sant'Ana AB, Vilela-Costa HH, Zangrossi H. New Findings on the Neurotransmitter Modulation of Defense in the Dorsal Periaqueductal Gray. Cns & Neurological Disorders Drug Targets. 14: 988-95. PMID 26350338 DOI: 10.2174/1871527314666150909114558  0.422
2015 Roncon CM, Almada RC, Maraschin JC, Audi EA, Zangrossi H, Graeff FG, Coimbra NC. Pharmacological evidence for the mediation of the panicolytic effect of fluoxetine by dorsal periaqueductal gray matter μ-opioid receptors. Neuropharmacology. 99: 620-626. PMID 26320545 DOI: 10.1016/J.Neuropharm.2015.08.037  0.379
2014 Rangel MP, Zangrossi H, Roncon CM, Graeff FG, Audi EA. Interaction between μ-opioid and 5-HT1A receptors in the regulation of panic-related defensive responses in the rat dorsal periaqueductal grey. Journal of Psychopharmacology (Oxford, England). 28: 1155-60. PMID 25315826 DOI: 10.1177/0269881114554274  0.396
2014 Garcia-Leal C, Graeff FG, Del-Ben CM. Experimental public speaking: contributions to the understanding of the serotonergic modulation of fear. Neuroscience and Biobehavioral Reviews. 46: 407-17. PMID 25277282 DOI: 10.1016/J.Neubiorev.2014.09.011  0.371
2014 Reis FM, Pestana-Oliveira N, Leite CM, Lima FB, Brandão ML, Graeff FG, Del-Ben CM, Anselmo-Franci JA. Hormonal changes and increased anxiety-like behavior in a perimenopause-animal model induced by 4-vinylcyclohexene diepoxide (VCD) in female rats. Psychoneuroendocrinology. 49: 130-40. PMID 25080405 DOI: 10.1016/J.Psyneuen.2014.06.019  0.358
2014 Canteras NS, Graeff FG. Executive and modulatory neural circuits of defensive reactions: implications for panic disorder. Neuroscience and Biobehavioral Reviews. 46: 352-64. PMID 24709069 DOI: 10.1016/J.Neubiorev.2014.03.020  0.389
2014 Zangrossi H, Graeff FG. Serotonin in anxiety and panic: contributions of the elevated T-maze. Neuroscience and Biobehavioral Reviews. 46: 397-406. PMID 24657635 DOI: 10.1016/J.Neubiorev.2014.03.007  0.471
2014 Audi E, Rangel M, Zangrossi H, Graeff F. P.4.a.003 Interaction between μ-opiod and 5-HT1A receptors in the regulation of panic-related defensive responses in rats European Neuropsychopharmacology. 24: S578. DOI: 10.1016/S0924-977X(14)70926-5  0.329
2014 Roncon CM, Almada RC, Maraschin JC, Elias-Filho DH, Audi EA, Zangrossi H, Graeff FG, Coimbra NC. P.1.g.028 Involvement of μ opioid receptor in the fluoxetine antipanic effect on rats submitted to the elevated T maze test European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70339-6  0.31
2013 Andrade TG, Zangrossi H, Graeff FG. The median raphe nucleus in anxiety revisited. Journal of Psychopharmacology (Oxford, England). 27: 1107-15. PMID 23999409 DOI: 10.1177/0269881113499208  0.434
2013 Roncon CM, Biesdorf C, Coimbra NC, Audi EA, Zangrossi H, Graeff FG. Cooperative regulation of anxiety and panic-related defensive behaviors in the rat periaqueductal grey matter by 5-HT1A and μ-receptors. Journal of Psychopharmacology (Oxford, England). 27: 1141-8. PMID 23598399 DOI: 10.1177/0269881113485144  0.401
2013 Moreira FA, Gobira PH, Viana TG, Vicente MA, Zangrossi H, Graeff FG. Modeling panic disorder in rodents. Cell and Tissue Research. 354: 119-25. PMID 23584609 DOI: 10.1007/S00441-013-1610-1  0.36
2013 de Rezende MG, Garcia-Leal C, Graeff FG, Del-Ben CM. The 5-HT1D/1B receptor agonist sumatriptan enhances fear of simulated speaking and reduces plasma levels of prolactin. Journal of Psychopharmacology (Oxford, England). 27: 1124-33. PMID 23325368 DOI: 10.1177/0269881112472560  0.422
2012 Graeff FG. New perspective on the pathophysiology of panic: merging serotonin and opioids in the periaqueductal gray. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 45: 366-75. PMID 22437485 DOI: 10.1590/S0100-879X2012007500036  0.388
2012 Roncon CM, Biesdorf C, Santana RG, Zangrossi H, Graeff FG, Audi EA. The panicolytic-like effect of fluoxetine in the elevated T-maze is mediated by serotonin-induced activation of endogenous opioids in the dorsal periaqueductal grey. Journal of Psychopharmacology (Oxford, England). 26: 525-31. PMID 22279131 DOI: 10.1177/0269881111434619  0.424
2012 de Oliveira DC, Zuardi AW, Graeff FG, Queiroz RH, Crippa JA. Anxiolytic-like effect of oxytocin in the simulated public speaking test. Journal of Psychopharmacology (Oxford, England). 26: 497-504. PMID 21555332 DOI: 10.1177/0269881111400642  0.304
2012 Del-Ben CM, Ferreira CA, Sanchez TA, Alves-Neto WC, Guapo VG, de Araujo DB, Graeff FG. Effects of diazepam on BOLD activation during the processing of aversive faces. Journal of Psychopharmacology (Oxford, England). 26: 443-51. PMID 21106607 DOI: 10.1177/0269881110389092  0.307
2011 Mesquita SC, Shuhama R, Osório FL, Crippa JA, Loureiro SR, Landeira-Fernandez J, Graeff FG, Del-Ben CM. The response of social anxiety disorder patients to threat scenarios differs from that of healthy controls. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 44: 1261-8. PMID 22011960 DOI: 10.1590/S0100-879X2011007500137  0.335
2011 Sela VR, Biesdorf C, Ramos DH, Zangrossi H, Graeff FG, Audi EA. Serotonin-1A receptors in the dorsal periaqueductal gray matter mediate the panicolytic-like effect of pindolol and paroxetine combination in the elevated T-maze. Neuroscience Letters. 495: 63-6. PMID 21421022 DOI: 10.1016/J.Neulet.2011.03.040  0.426
2011 Graeff FG. Defense-related emotions in humans Psychology and Neuroscience. 4: 183-189. DOI: 10.3922/J.Psns.2011.2.003  0.387
2010 Sela VR, Roncon CM, Zangrossi H, Graeff FG, Audi EA. Pindolol potentiates the panicolytic effect of paroxetine in the elevated T-maze. Life Sciences. 87: 445-50. PMID 20816996 DOI: 10.1016/J.Lfs.2010.08.009  0.396
2010 Graeff FG, Zangrossi H. The dual role of serotonin in defense and the mode of action of antidepressants on generalized anxiety and panic disorders. Central Nervous System Agents in Medicinal Chemistry. 10: 207-17. PMID 20528764 DOI: 10.2174/1871524911006030207  0.454
2010 Alves-Neto WC, Guapo VG, Graeff FG, Deakin JF, Del-Ben CM. Effect of escitalopram on the processing of emotional faces. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 43: 285-9. PMID 20209375 DOI: 10.1590/S0100-879X2010005000007  0.31
2010 dos Santos L, de Andrade TG, Graeff FG. Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus. Journal of Psychopharmacology (Oxford, England). 24: 725-31. PMID 19939879 DOI: 10.1177/0269881109106954  0.344
2010 Garcia-Leal C, Del-Ben CM, Leal FM, Graeff FG, Guimarães FS. Escitalopram prolonged fear induced by simulated public speaking and released hypothalamic-pituitary-adrenal axis activation. Journal of Psychopharmacology (Oxford, England). 24: 683-94. PMID 19251828 DOI: 10.1177/0269881108101782  0.39
2010 Graeff FG, Junior HZ. The hypothalamic-pituitary-adrenal axis in anxiety and panic Psychology and Neuroscience. 3. DOI: 10.3922/J.Psns.2010.1.002  0.371
2010 Guimarães FS, Zangrossi H, Ben CMD, Graeff FG. Serotonin in panic and anxiety disorders Handbook of Behavioral Neuroscience. 21: 667-685. DOI: 10.1016/S1569-7339(10)70105-3  0.415
2009 Andrade TG, Avanzi V, Graeff FG. Effect of estradiol benzoate microinjection into the median raphe nucleus on contextual conditioning. Behavioural Brain Research. 204: 112-6. PMID 19482044 DOI: 10.1016/J.Bbr.2009.05.029  0.391
2009 Del-Ben CM, Graeff FG. Panic disorder: is the PAG involved? Neural Plasticity. 2009: 108135. PMID 19283082 DOI: 10.1155/2009/108135  0.3
2009 Garcia-Leal C, Del-Ben C, Leal F, Graeff F, Guimarães F. P02-229 Escitalopram prolonged fear induced by simulated public speaking and released hypothalamic-pituitary-adrenal axis activation European Psychiatry. 24: S919. DOI: 10.1016/S0924-9338(09)71152-6  0.392
2008 Graeff FG, Del-Ben CM. Neurobiology of panic disorder: from animal models to brain neuroimaging. Neuroscience and Biobehavioral Reviews. 32: 1326-35. PMID 18573531 DOI: 10.1016/J.Neubiorev.2008.05.017  0.368
2008 Del-Ben CM, Ferreira CA, Alves-Neto WC, Graeff FG. Serotonergic modulation of face-emotion recognition. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 41: 263-9. PMID 18392448 DOI: 10.1590/S0100-879X2008000400002  0.36
2008 Pinheiro SN, Del-Ben CM, Zangrossi H, Graeff FG. Anxiolytic and panicolytic effects of escitalopram in the elevated T-maze. Journal of Psychopharmacology (Oxford, England). 22: 132-7. PMID 18208911 DOI: 10.1177/0269881107079866  0.385
2008 Guimarães FS, Carobrez AP, Graeff FG. Chapter 4.3 Modulation of anxiety behaviors by 5-HT-interacting drugs Handbook of Behavioral Neuroscience. 17: 241-268. DOI: 10.1016/S1569-7339(07)00012-4  0.42
2007 Graeff FG. [Anxiety, panic and the hypothalamic-pituitary-adrenal axis]. Revista Brasileira De Psiquiatria (Sã£O Paulo, Brazil : 1999). 29: S3-6. PMID 17546345 DOI: 10.1590/S1516-44462007000500002  0.357
2007 Shuhama R, Del-Ben CM, Loureiro SR, Graeff FG. Animal defense strategies and anxiety disorders. Anais Da Academia Brasileira De CiãªNcias. 79: 97-109. PMID 17401479 DOI: 10.1590/S0001-37652007000100012  0.347
2007 Pinheiro SH, Zangrossi H, Del-Ben CM, Graeff FG. Elevated mazes as animal models of anxiety: effects of serotonergic agents. Anais Da Academia Brasileira De CiãªNcias. 79: 71-85. PMID 17401477 DOI: 10.1590/S0001-37652007000100010  0.396
2005 Graeff FG, Garcia-Leal C, Del-Ben CM, Guimarães FS. Does the panic attack activate the hypothalamic-pituitary-adrenal axis? Anais Da Academia Brasileira De CiãªNcias. 77: 477-91. PMID 16127553 DOI: 10.1590/S0001-37652005000300009  0.347
2005 Parente AC, Garcia-Leal C, Del-Ben CM, Guimarães FS, Graeff FG. Subjective and neurovegetative changes in healthy volunteers and panic patients performing simulated public speaking. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 15: 663-71. PMID 15961294 DOI: 10.1016/J.Euroneuro.2005.05.002  0.322
2005 Andrade TG, Nakamuta JS, Avanzi V, Graeff FG. Anxiolytic effect of estradiol in the median raphe nucleus mediated by 5-HT1A receptors. Behavioural Brain Research. 163: 18-25. PMID 15951031 DOI: 10.1016/J.Bbr.2005.04.015  0.393
2005 Garcia-Leal C, Parente AC, Del-Ben CM, Guimarães FS, Moreira AC, Elias LL, Graeff FG. Anxiety and salivary cortisol in symptomatic and nonsymptomatic panic patients and healthy volunteers performing simulated public speaking. Psychiatry Research. 133: 239-52. PMID 15740999 DOI: 10.1016/J.Psychres.2004.04.010  0.333
2004 Graeff FG. Serotonin, the periaqueductal gray and panic. Neuroscience and Biobehavioral Reviews. 28: 239-59. PMID 15225969 DOI: 10.1016/J.Neubiorev.2003.12.004  0.452
2004 Andrade TG, Macedo CE, Zangrossi H, Graeff FG. Anxiolytic-like effects of median raphe nucleus lesion in the elevated T-maze. Behavioural Brain Research. 153: 55-60. PMID 15219706 DOI: 10.1016/J.Bbr.2003.10.036  0.388
2003 Graeff FG. [Serotonin, periaqueductal gray matter and panic disorder]. Revista Brasileira De Psiquiatria (Sã£O Paulo, Brazil : 1999). 25: 42-5. PMID 14978586 DOI: 10.1590/S1516-44462003000600010  0.45
2003 Graeff FG, Parente A, Del-Ben CM, Guimarães FS. Pharmacology of human experimental anxiety. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 36: 421-32. PMID 12700819 DOI: 10.1590/S0100-879X2003000400003  0.388
2002 Graeff FG. On serotonin and experimental anxiety. Psychopharmacology. 163: 467-76. PMID 12373447 DOI: 10.1007/S00213-002-1112-4  0.464
2001 Graeff FG, Silva M, Del Ben CM, Zuardi AW, Hetem LA, Guimarães FS. Comparison between two models of experimental anxiety in healthy volunteers and panic disorder patients. Neuroscience and Biobehavioral Reviews. 25: 753-9. PMID 11801299 DOI: 10.1016/S0149-7634(01)00055-0  0.432
2001 Carobrez AP, Teixeira KV, Graeff FG. Modulation of defensive behavior by periaqueductal gray NMDA/glycine-B receptor. Neuroscience and Biobehavioral Reviews. 25: 697-709. PMID 11801295 DOI: 10.1016/S0149-7634(01)00059-8  0.323
2001 Zangrossi H, Viana MB, Zanoveli J, Bueno C, Nogueira RL, Graeff FG. Serotonergic regulation of inhibitory avoidance and one-way escape in the rat elevated T-maze. Neuroscience and Biobehavioral Reviews. 25: 637-45. PMID 11801289 DOI: 10.1016/S0149-7634(01)00047-1  0.449
2001 Vianna DM, Graeff FG, Brandão ML, Landeira-Fernandez J. Defensive freezing evoked by electrical stimulation of the periaqueductal gray: comparison between dorsolateral and ventrolateral regions. Neuroreport. 12: 4109-12. PMID 11742247 DOI: 10.1097/00001756-200112210-00049  0.317
2001 Del-Ben CM, Vilela JA, Hetem LA, Guimarães FS, Graeff FG, Zuardi AW. Do panic patients process unconditioned fear vs. conditioned anxiety differently than normal subjects? Psychiatry Research. 104: 227-37. PMID 11728612 DOI: 10.1016/S0165-1781(01)00312-2  0.339
2001 Silveira MC, Zangrossi H, de Barros Viana M, Silveira R, Graeff FG. Differential expression of Fos protein in the rat brain induced by performance of avoidance or escape in the elevated T-maze. Behavioural Brain Research. 126: 13-21. PMID 11704247 DOI: 10.1016/S0166-4328(01)00233-9  0.341
2001 Silva M, Hetem LA, Guimarães FS, Graeff FG. Opposite effects of nefazodone in two human models of anxiety. Psychopharmacology. 156: 454-60. PMID 11498723 DOI: 10.1007/S002130100752  0.425
2001 Vianna DM, Graeff FG, Landeira-Fernandez J, Brandão ML. Lesion of the ventral periaqueductal gray reduces conditioned fear but does not change freezing induced by stimulation of the dorsal periaqueductal gray. Learning & Memory (Cold Spring Harbor, N.Y.). 8: 164-9. PMID 11390636 DOI: 10.1101/Lm.36101  0.359
2001 Andreatini R, Blanchard C, Blanchard R, Brandão ML, Carobrez AP, Griebel G, Guimarães FS, Handley SL, Jenck F, Leite JR, Rodgers J, Schenberg LC, Da Cunha C, Graeff FG. The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 34: 145-54. PMID 11175489 DOI: 10.1590/S0100-879X2001000200001  0.554
2001 Graeff FG. Aspectos neuroquímicos: o papel da serotonina no TOC Revista Brasileira De Psiquiatria. 23: 35-37. DOI: 10.1590/S1516-44462001000600011  0.399
2001 Blanchard RJ, Blanchard DC, Graeff FG. Foreword Neuroscience and Biobehavioral Reviews. 25: 575-576. DOI: 10.1016/S0149-7634(01)00061-6  0.535
2000 Salgado JV, Hetem LA, Vidal M, Graeff FG, Danion JM, Sandner G. Reduction of latent inhibition by D-amphetamine in a conditioned suppression paradigm in humans. Behavioural Brain Research. 117: 61-7. PMID 11099758 DOI: 10.1016/S0166-4328(00)00279-5  0.313
2000 Nunes-de-Souza RL, Canto-de-Souza A, da-Costa M, Fornari RV, Graeff FG, Pelá IR. Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam. Psychopharmacology. 150: 300-10. PMID 10923758 DOI: 10.1007/S002130000428  0.46
2000 Teixeira RC, Zangrossi H, Graeff FG. Behavioral effects of acute and chronic imipramine in the elevated T-maze model of anxiety. Pharmacology, Biochemistry, and Behavior. 65: 571-6. PMID 10764908 DOI: 10.1016/S0091-3057(99)00261-0  0.379
1999 Zangrossi H, Viana MB, Graeff FG. Anxiolytic effect of intra-amygdala injection of midazolam and 8-hydroxy-2-(di-n-propylamino)tetralin in the elevated T-maze. European Journal of Pharmacology. 369: 267-70. PMID 10225362 DOI: 10.1016/S0014-2999(99)00075-8  0.404
1999 De Oliveira Mora P, Fouquet N, Oberling P, Gobaille S, Graeff FG, Sandner G. A neurotoxic lesion of serotonergic neurones using 5,7-dihydroxytryptamine does not disrupt latent inhibition in paradigms sensitive to low doses of amphetamine. Behavioural Brain Research. 100: 167-75. PMID 10212064 DOI: 10.1016/S0166-4328(98)00128-4  0.356
1998 Graeff FG, Netto CF, Zangrossi H. The elevated T-maze as an experimental model of anxiety. Neuroscience and Biobehavioral Reviews. 23: 237-46. PMID 9884116 DOI: 10.1016/S0149-7634(98)00024-4  0.471
1998 Canto-de-Souza A, Nunes de Souza RL, Pelá IR, Graeff FG. Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice. European Journal of Pharmacology. 345: 253-6. PMID 9592023 DOI: 10.1016/S0014-2999(98)00018-1  0.323
1997 Graeff FG, Viana MB, Mora PO. Dual role of 5-HT in defense and anxiety. Neuroscience and Biobehavioral Reviews. 21: 791-9. PMID 9415904 DOI: 10.1016/S0149-7634(96)00059-0  0.442
1997 Mora PO, Netto CF, Graeff FG. Role of 5-HT2A and 5-HT2C receptor subtypes in the two types of fear generated by the elevated T-maze. Pharmacology, Biochemistry, and Behavior. 58: 1051-7. PMID 9408213 DOI: 10.1016/S0091-3057(97)00057-9  0.435
1997 Zangrossi H, Graeff FG. Behavioral validation of the elevated T-maze, a new animal model of anxiety. Brain Research Bulletin. 44: 1-5. PMID 9288825 DOI: 10.1016/S0361-9230(96)00381-4  0.361
1997 Viana MB, Graeff FG, Löschmann PA. Kainate microinjection into the dorsal raphe nucleus induces 5-HT release in the amygdala and periaqueductal gray. Pharmacology, Biochemistry, and Behavior. 58: 167-72. PMID 9264086 DOI: 10.1016/S0091-3057(96)00451-0  0.452
1997 Canto de Souza A, Nunes de Souza RL, Péla IR, Graeff FG. High intensity social conflict in the Swiss albino mouse induces analgesia modulated by 5-HT1A receptors. Pharmacology, Biochemistry, and Behavior. 56: 481-6. PMID 9077586 DOI: 10.1016/S0091-3057(96)00246-8  0.308
1996 Hetem LA, de Souza CJ, Guimarães ES, Zuardi AW, Graeff FG. Effect of d-fenfluramine on human experimental anxiety. Psychopharmacology. 127: 276-82. PMID 8912406 DOI: 10.1007/S002130050086  0.449
1996 Graeff FG, Viana MB, Mora PO. Opposed regulation by dorsal raphe nucleus 5-HT pathways of two types of fear in the elevated T-maze. Pharmacology, Biochemistry, and Behavior. 53: 171-7. PMID 8848447 DOI: 10.1016/0091-3057(95)02012-8  0.456
1996 Gargiulo PA, Viana MB, Graeff FG, Silva MA, Tomaz C. Effects of anxiety and memory of systemic and intra-amygdala injection of 5-HT3 receptor antagonist BRL 46470A. Neuropsychobiology. 33: 189-95. PMID 8840342 DOI: 10.1159/000119276  0.429
1996 Scorza MC, Reyes-Parada M, Silveira R, Viola H, Medina JH, Viana MB, Zangrossi H, Graeff FG. Behavioral effects of the putative anxiolytic (+/-)-1-(2,5-dimethoxy-4-ethylthiophenyl)-2-aminopropane (ALEPH-2) in rats and mice. Pharmacology, Biochemistry, and Behavior. 54: 355-61. PMID 8743595 DOI: 10.1016/0091-3057(95)02149-3  0.353
1996 Graeff FG, Guimarães FS, De Andrade TG, Deakin JF. Role of 5-HT in stress, anxiety, and depression. Pharmacology, Biochemistry, and Behavior. 54: 129-41. PMID 8728550 DOI: 10.1016/0091-3057(95)02135-3  0.45
1995 Silveira MC, Sandner G, Di Scala G, Graeff FG. c-fos immunoreactivity in the brain following electrical or chemical stimulation of the medial hypothalamus of freely moving rats. Brain Research. 674: 265-74. PMID 7796106 DOI: 10.1016/0006-8993(94)01451-M  0.309
1995 Nogueira RL, Graeff FG. Role of 5-HT receptor subtypes in the modulation of dorsal periaqueductal gray generated aversion. Pharmacology, Biochemistry, and Behavior. 52: 1-6. PMID 7501649 DOI: 10.1016/0091-3057(94)00402-5  0.414
1995 Graeff FG, de Barros Viana M, de Oliveira Mora P, Guimar??es FS, Hetem LA. Dual role of 5-HT in experimental anxiety Behavioural Pharmacology. 6: 146. DOI: 10.1097/00008877-199505001-00174  0.382
1995 Connell J, Graeff F, Guimareas F, Hellewell JS, Hettem LA, Deakin JF. 5HT2 receptors and anxiety Behavioural Pharmacology. 6: 35. DOI: 10.1097/00008877-199505001-00039  0.391
1994 Graeff FG. Neuroanatomy and neurotransmitter regulation of defensive behaviors and related emotions in mammals. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 27: 811-29. PMID 7916235  0.307
1994 Matheus MG, Nogueira RL, Carobrez AP, Graeff FG, Guimarães FS. Anxiolytic effect of glycine antagonists microinjected into the dorsal periaqueductal grey. Psychopharmacology. 113: 565-9. PMID 7862877 DOI: 10.1007/Bf02245241  0.399
1994 Viana MB, Tomaz C, Graeff FG. The elevated T-maze: a new animal model of anxiety and memory. Pharmacology, Biochemistry, and Behavior. 49: 549-54. PMID 7862706 DOI: 10.1016/0091-3057(94)90067-1  0.357
1994 Zangrossi Júnior H, Graeff FG. Behavioral effects of intra-amygdala injections of GABA and 5-HT acting drugs in the elevated plus-maze. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 27: 2453-6. PMID 7640637  0.332
1993 Zuardi AW, Cosme RA, Graeff FG, Guimarães FS. Effects of ipsapirone and cannabidiol on human experimental anxiety. Journal of Psychopharmacology (Oxford, England). 7: 82-8. PMID 22290374 DOI: 10.1177/026988119300700112  0.364
1993 Silveira MC, Sandner G, Graeff FG. Induction of Fos immunoreactivity in the brain by exposure to the elevated plus-maze. Behavioural Brain Research. 56: 115-8. PMID 8397853 DOI: 10.1016/0166-4328(93)90028-O  0.327
1993 de Souza Silva M, Guimarães FS, Graeff FG, Tomaz C. Absence of amnestic effect of an anxiolytic 5-HT3 antagonist (BRL 46470A) injected into basolateral amygdala, as opposed to diazepam. Behavioural Brain Research. 59: 141-5. PMID 8155281 DOI: 10.1016/0166-4328(93)90160-R  0.37
1993 Tomaz C, Dickinson-Anson H, McGaugh JL, Souza-Silva MA, Viana MB, Graeff FG. Localization in the amygdala of the amnestic action of diazepam on emotional memory. Behavioural Brain Research. 58: 99-105. PMID 8136053 DOI: 10.1016/0166-4328(93)90094-7  0.338
1993 Graeff FG, Silveira MC, Nogueira RL, Audi EA, Oliveira RM. Role of the amygdala and periaqueductal gray in anxiety and panic. Behavioural Brain Research. 58: 123-31. PMID 8136040 DOI: 10.1016/0166-4328(93)90097-A  0.452
1993 Graeff FG. Role of 5-HT in defensive behavior and anxiety. Reviews in the Neurosciences. 4: 181-211. PMID 7952387 DOI: 10.1515/Revneuro.1993.4.2.181  0.397
1993 Russo AS, Guimarães FS, De Aguiar JC, Graeff FG. Role of benzodiazepine receptors located in the dorsal periaqueductal grey of rats in anxiety. Psychopharmacology. 110: 198-202. PMID 7870885 DOI: 10.1007/Bf02246973  0.435
1992 Silveira MC, Graeff FG. Defense reaction elicited by microinjection of kainic acid into the medial hypothalamus of the rat: antagonism by a GABAA receptor agonist. Behavioral and Neural Biology. 57: 226-32. PMID 1319704 DOI: 10.1016/0163-1047(92)90192-7  0.316
1991 Deakin JF, Graeff FG. 5-HT and mechanisms of defence. Author's response. Journal of Psychopharmacology (Oxford, England). 5: 339-41. PMID 22282838 DOI: 10.1177/026988119100500423  0.332
1991 Deakin JF, Graeff FG. 5-HT and mechanisms of defence. Journal of Psychopharmacology (Oxford, England). 5: 305-15. PMID 22282829 DOI: 10.1177/026988119100500414  0.335
1991 Audi EA, de Oliveira RM, Graeff FG. Microinjection of propranolol into the dorsal periaqueductal gray causes an anxiolytic effect in the elevated plus-maze antagonized by ritanserin. Psychopharmacology. 105: 553-7. PMID 1685253 DOI: 10.1007/Bf02244379  0.409
1991 Brandão ML, Lopez-Garcia JA, Graeff FG, Roberts MH. Electrophysiological evidence for excitatory 5-HT2 and depressant 5-HT1A receptors on neurones of the rat midbrain tectum. Brain Research. 556: 259-66. PMID 1682008 DOI: 10.1016/0006-8993(91)90313-K  0.39
1991 Deakin JFW, Graeff FG, Rodgers RJ, Broekkamp CL, Handley SL, McBlane JW, Everitt B, Robbins T, Shepherd JK, Blanchard DC, De Padua Carobrez A, Blanchard RJ, Wetzler S, Asnis GM, Van Praag HM, et al. Critique: 5-HT and mechanisms of defence Journal of Psychopharmacology. 5: 305-341.  0.57
1990 Graeff FG, Audi EA, Almeida SS, Graeff EO, Hunziker MH. Behavioral effects of 5-HT receptor ligands in the aversive brain stimulation, elevated plus-maze and learned helplessness tests. Neuroscience and Biobehavioral Reviews. 14: 501-6. PMID 2287488 DOI: 10.1016/S0149-7634(05)80074-0  0.425
1990 Almeida SS, de Oliveira LM, Graeff FG. Decreased reactivity to anxiolytics caused by early protein malnutrition in rats. Pharmacology, Biochemistry, and Behavior. 36: 997-1000. PMID 1977181 DOI: 10.1016/0091-3057(90)90113-V  0.317
1990 Guimarães FS, Chiaretti TM, Graeff FG, Zuardi AW. Antianxiety effect of cannabidiol in the elevated plus-maze. Psychopharmacology. 100: 558-9. PMID 1969666 DOI: 10.1007/Bf02244012  0.349
1989 Audi EA, de-Oliveira CE, Graeff FG. Serotonergic mediation of the anxiolytic effect of intracerebrally injected propranolol measured in the elevated plus-maze. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 22: 699-701. PMID 2515907  0.341
1988 Audi EA, de Aguiar JC, Graeff FG. Mediation by serotonin of the antiaversive effect of zimelidine and propranolol injected into the dorsal midbrain central grey. Journal of Psychopharmacology (Oxford, England). 2: 26-32. PMID 22159666 DOI: 10.1177/026988118800200105  0.433
1987 Guimarães FS, Zuardi AW, Graeff FG. Effect of chlorimipramine and maprotiline on experimental anxiety in humans. Journal of Psychopharmacology (Oxford, England). 1: 184-92. PMID 22158980 DOI: 10.1177/026988118700100305  0.42
1987 Audi EA, Graeff FG. GABAA receptors in the midbrain central grey mediate the antiaversive action of GABA. European Journal of Pharmacology. 135: 225-9. PMID 3034627 DOI: 10.1016/0014-2999(87)90615-7  0.349
1986 Graeff FG, Brandão ML, Audi EA, Schütz MT. Modulation of the brain aversive system by GABAergic and serotonergic mechanisms. Behavioural Brain Research. 22: 173-80. PMID 3024664 DOI: 10.1016/0166-4328(85)90120-2  0.305
1985 Graeff FG, Zuardi AW, Giglio JS, Lima Filho EC, Karniol IG. Effect of metergoline on human anxiety. Psychopharmacology. 86: 334-8. PMID 3929304 DOI: 10.1007/Bf00432224  0.412
1985 Schütz MT, de Aguiar JC, Graeff FG. Anti-aversive role of serotonin in the dorsal periaqueductal grey matter. Psychopharmacology. 85: 340-5. PMID 3159032 DOI: 10.1007/Bf00428199  0.403
1984 Audi EA, Graeff FG. Benzodiazepine receptors in the periaqueductal grey mediate anti-aversive drug action. European Journal of Pharmacology. 103: 279-85. PMID 6092103 DOI: 10.1016/0014-2999(84)90488-6  0.36
1984 Graeff FG. The anti-aversive action of minor tranquillizers Trends in Pharmacological Sciences. 5: 230-233. DOI: 10.1016/0165-6147(84)90428-0  0.363
1983 Carobrez AP, Schenberg LC, Graeff FG. Neuroeffector mechanisms of the defense reaction in the rat. Physiology & Behavior. 31: 439-44. PMID 6657764 DOI: 10.1016/0031-9384(83)90063-X  0.352
1983 Schenberg LC, De Aguiar JC, Graeff FG. GABA modulation of the defense reaction induced by brain electrical stimulation. Physiology & Behavior. 31: 429-37. PMID 6318241 DOI: 10.1016/0031-9384(83)90062-8  0.366
1981 Morato de Carvalho S, de Aguiar JC, Graeff FG. Effect of minor tranquilizers, tryptamine antagonists and amphetamine on behavior punished by brain stimulation. Pharmacology, Biochemistry, and Behavior. 15: 351-6. PMID 6117081 DOI: 10.1016/0091-3057(81)90261-6  0.382
1980 Brandão ML, Fontes JC, Graeff FG. Facilitatory effect of ketamine on punished behavior. Pharmacology, Biochemistry, and Behavior. 13: 1-4. PMID 7403212 DOI: 10.1016/0091-3057(80)90110-0  0.323
1980 Graeff FG, Rawlins JN. Dorsal periaqueductal gray punishment, septal lesions and the mode of action of minor tranquilizers. Pharmacology, Biochemistry, and Behavior. 12: 41-5. PMID 7367461 DOI: 10.1016/0091-3057(80)90413-X  0.61
1980 Graeff FG, Quintero S, Gray JA. Median raphe stimulation, hippocampal theta rhythm and threat-induced behavioral inhibition. Physiology & Behavior. 25: 253-61. PMID 6447883 DOI: 10.1016/0031-9384(80)90213-9  0.504
1978 Schenberg LC, Graeff FG. Role of the periaqueductal gray substance in the antianxiety action of benzodiazepines. Pharmacology, Biochemistry, and Behavior. 9: 287-95. PMID 568804 DOI: 10.1016/0091-3057(78)90287-3  0.369
1976 Corrêa FM, Graeff FG. On the mechanism of the hypertensive action of intraseptal bradykinin in the rat. Neuropharmacology. 15: 713-7. PMID 1004694 DOI: 10.1016/0028-3908(76)90042-3  0.304
1975 Graeff FG, De Oliveira L. Influence of response topography on the effect of apomorphine and amphetamine on operant behavior of pigeons. Psychopharmacologia. 41: 127-32. PMID 1171486 DOI: 10.1007/Bf00421069  0.314
1974 Peres VL, Gentil CG, Graeff FG, Covian MR. Antagonism of the dipsogenic action of intraseptal angiotensin II in the rat. Pharmacology, Biochemistry, and Behavior. 2: 597-602. PMID 4372640 DOI: 10.1016/0091-3057(74)90026-4  0.301
1973 Graeff FG, Gentil CG, Peres VL, Covian MR. Lever-pressing behavior caused by intraseptal angiotensin II in water satiated rats. Pharmacology, Biochemistry, and Behavior. 1: 357-9. PMID 4359806 DOI: 10.1016/0091-3057(73)90129-9  0.306
1971 Ribeiro SA, Corrado AP, Graeff FG. Antinociceptive action of intraventricular bradykinin. Neuropharmacology. 10: 725-31. PMID 5316055 DOI: 10.1016/0028-3908(71)90087-6  0.305
1970 Graeff FG, Schoenfeld RI. Tryptaminergic mechanisms in punished and nonpunished behavior. The Journal of Pharmacology and Experimental Therapeutics. 173: 277-83. PMID 5434014  0.6
1969 Graeff FG, Pelá IR, Roch e Silva M. Behavioural and somatic effects of bradykinin injected into the cerebral ventricles of unanaesthetized rabbits. British Journal of Pharmacology. 37: 723-32. PMID 5388583 DOI: 10.1016/S0031-6989(69)80077-9  0.322
1965 GRAEFF FG, LEME JG, ROCHAESILVA M. ROLE PLAYED BY CATECHOL AND INDOLAMINES IN THE CENTRAL ACTIONS OF RESERPINE AFTER MONO-AMINOXIDASE INHIBITION. International Journal of Neuropharmacology. 4: 17-26. PMID 14346146 DOI: 10.1016/0028-3908(65)90043-2  0.349
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