| Year |
Citation |
Score |
| 2023 |
Nelson AB, Queathem ED, Puchalska P, Crawford PA. Metabolic Messengers: ketone bodies. Nature Metabolism. PMID 38092961 DOI: 10.1038/s42255-023-00935-3 |
0.332 |
|
| 2023 |
Alexander M, Upadhyay V, Rock R, Ramirez L, Puchalska P, Orellana D, Ang QY, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity. Biorxiv : the Preprint Server For Biology. PMID 37961209 DOI: 10.1101/2023.11.02.565382 |
0.614 |
|
| 2023 |
Tabatabaei Dakhili SA, Yang K, Locatelli CAA, Saed CT, Greenwell AA, Chan JSF, Chahade JJ, Scharff J, Al-Imarah S, Eaton F, Crawford PA, Gopal K, Mulvihill EE, Ussher JR. Ketone ester administration improves glycemia in obese mice. American Journal of Physiology. Cell Physiology. 325: C750-C757. PMID 37575059 DOI: 10.1152/ajpcell.00300.2023 |
0.318 |
|
| 2023 |
Matsuura TR, Puchalska P, Crawford PA, Kelly DP. Ketones and the Heart: Metabolic Principles and Therapeutic Implications. Circulation Research. 132: 882-898. PMID 36996176 DOI: 10.1161/CIRCRESAHA.123.321872 |
0.34 |
|
| 2023 |
Mechchate H, Abdualkader AM, Bernacchi JB, Gopal K, Tabatabaei Dakhili SA, Yang K, Greenwell AA, Kong X, Crawford PA, Al Batran R. Defective Muscle Ketone Body Oxidation Disrupts BCAA Catabolism by Altering Mitochondrial Branched-Chain Aminotransferase. American Journal of Physiology. Endocrinology and Metabolism. PMID 36989424 DOI: 10.1152/ajpendo.00206.2022 |
0.378 |
|
| 2022 |
Rome FI, Shobert GL, Voigt WC, Stagg DB, Puchalska P, Burgess SC, Crawford PA, Hughey CC. Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice. American Journal of Physiology. Endocrinology and Metabolism. PMID 36351254 DOI: 10.1152/ajpendo.00222.2022 |
0.307 |
|
| 2022 |
Hughey CC, Puchalska P, Crawford PA. Integrating the contributions of mitochondrial oxidative metabolism to lipotoxicity and inflammation in NAFLD pathogenesis. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1867: 159209. PMID 35934297 DOI: 10.1016/j.bbalip.2022.159209 |
0.311 |
|
| 2022 |
Weis EM, Puchalska P, Nelson AB, Taylor J, Moll I, Hasan SS, Dewenter M, Hagenmüller M, Fleming T, Poschet G, Hotz-Wagenblatt A, Backs J, Crawford PA, Fischer A. Ketone body oxidation increases cardiac endothelial cell proliferation. Embo Molecular Medicine. e14753. PMID 35179309 DOI: 10.15252/emmm.202114753 |
0.386 |
|
| 2021 |
Puchalska P, Crawford PA. Metabolic and Signaling Roles of Ketone Bodies in Health and Disease. Annual Review of Nutrition. 41: 49-77. PMID 34633859 DOI: 10.1146/annurev-nutr-111120-111518 |
0.307 |
|
| 2021 |
Stagg DB, Gillingham JR, Nelson AB, Lengfeld JE, André d'Avignon D, Puchalska P, Crawford PA. Diminished ketone interconversion, hepatic TCA cycle flux, and glucose production in D-β-hydroxybutyrate dehydrogenase hepatocyte-deficient mice. Molecular Metabolism. 101269. PMID 34116232 DOI: 10.1016/j.molmet.2021.101269 |
0.367 |
|
| 2020 |
Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, ... ... Crawford PA, et al. Mitochondrial pyruvate carriers are required for myocardial stress adaptation. Nature Metabolism. PMID 33106689 DOI: 10.1038/s42255-020-00288-1 |
0.381 |
|
| 2020 |
Al Batran R, Gopal K, Capozzi ME, Chahade JJ, Saleme B, Tabatabaei-Dakhili SA, Greenwell AA, Niu J, Almutairi M, Byrne NJ, Masson G, Kim R, Eaton F, Mulvihill EE, Garneau L, ... ... Crawford PA, et al. Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation. Cell Metabolism. PMID 32275862 DOI: 10.1016/J.Cmet.2020.03.017 |
0.428 |
|
| 2020 |
Sheka AC, Adeyi O, Thompson J, Hameed B, Crawford PA, Ikramuddin S. Nonalcoholic Steatohepatitis: A Review. Jama. 323: 1175-1183. PMID 32207804 DOI: 10.1001/Jama.2020.2298 |
0.314 |
|
| 2019 |
Hughey CC, Crawford PA. Pyruvate Carboxylase Wields a Double-Edged Metabolic Sword. Cell Metabolism. 29: 1236-1238. PMID 31167118 DOI: 10.1016/J.Cmet.2019.05.013 |
0.411 |
|
| 2019 |
Puchalska P, Crawford PA. Application of Stable Isotope Labels for Metabolomics in Studies in Fatty Liver Disease. Methods in Molecular Biology (Clifton, N.J.). 1996: 259-272. PMID 31127561 DOI: 10.1007/978-1-4939-9488-5_20 |
0.435 |
|
| 2019 |
Horton JL, Davidson MT, Kurishima C, Vega RB, Powers JC, Matsuura TR, Petucci C, Lewandowski ED, Crawford PA, Muoio DM, Recchia FA, Kelly DP. The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense. Jci Insight. PMID 30668551 DOI: 10.1172/Jci.Insight.124079 |
0.387 |
|
| 2019 |
PUCHALSKA P, LENGFELD JE, STAGG DB, CRAWFORD PA. 1867-P: The Role of Ketone Bodies in Diabetes Pathogenesis Using Untargeted Metabolomics Diabetes. 68: 1867-P. DOI: 10.2337/Db19-1867-P |
0.499 |
|
| 2018 |
Niu X, Chen YJ, Crawford PA, Patti GJ. Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells. Cancer & Metabolism. 6: 19. PMID 30559963 DOI: 10.1186/S40170-018-0192-5 |
0.391 |
|
| 2018 |
Puchalska P, Martin SE, Huang X, Lengfeld JE, Daniel B, Graham MJ, Han X, Nagy L, Patti GJ, Crawford PA. Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis. Cell Metabolism. PMID 30449686 DOI: 10.1016/J.Cmet.2018.10.015 |
0.408 |
|
| 2018 |
Puchalska P, Huang X, Martin SE, Han X, Patti GJ, Crawford PA. Isotope Tracing Untargeted Metabolomics Reveals Macrophage Polarization-State-Specific Metabolic Coordination across Intracellular Compartments. Iscience. 9: 298-313. PMID 30448730 DOI: 10.1016/J.Isci.2018.10.029 |
0.315 |
|
| 2018 |
Wang C, Liu F, Frisch-Daiello JL, Martin S, Patterson TA, Gu Q, Liu S, Paule MG, Hanig JP, Slikker W, Crawford PA, Wang C, Han X. Lipidomics reveals a systemic energy deficient state that precedes neurotoxicity in neonatal monkeys after sevoflurane exposure. Analytica Chimica Acta. 1037: 87-96. PMID 30292318 DOI: 10.1016/J.Aca.2017.11.052 |
0.32 |
|
| 2018 |
d'Avignon DA, Puchalska P, Ercal B, Chang Y, Martin SE, Graham MJ, Patti GJ, Han X, Crawford PA. Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome. Jci Insight. 3. PMID 29925686 DOI: 10.1172/Jci.Insight.99762 |
0.494 |
|
| 2018 |
Ruan HB, Crawford PA. Ketone bodies as epigenetic modifiers. Current Opinion in Clinical Nutrition and Metabolic Care. PMID 29697540 DOI: 10.1097/Mco.0000000000000475 |
0.406 |
|
| 2018 |
Polidori D, Iijima H, Goda M, Maruyama N, Inagaki N, Crawford PA. Intra- and Inter-Subject Variability for Increases in Serum Ketone Bodies in Patients With Type 2 Diabetes Treated With the Sodium Glucose Co-transporter 2 Inhibitor Canagliflozin. Diabetes, Obesity & Metabolism. PMID 29341404 DOI: 10.1111/Dom.13224 |
0.34 |
|
| 2017 |
Ruiz M, Labarthe F, Fortier A, Bouchard B, Thompson Legault J, Bolduc V, Rigal O, Chen J, Ducharme A, Crawford PA, Tardif JC, Des Rosiers C. Circulating Acylcarnitine Profile in Human Heart Failure: A Surrogate of Fatty Acid Metabolic Dysregulation in Mitochondria and Beyond. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00820.2016. PMID 28710072 DOI: 10.1152/Ajpheart.00820.2016 |
0.411 |
|
| 2017 |
Puchalska P, Crawford PA. Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics. Cell Metabolism. 25: 262-284. PMID 28178565 DOI: 10.1016/J.Bpj.2018.11.034 |
0.451 |
|
| 2016 |
Wang C, Palavicini JP, Wang M, Chen L, Yang K, Crawford PA, Han X. Comprehensive and Quantitative Analysis of Polyphosphoinositide Species by Shotgun Lipidomics Revealed Their Alterations in db/db Mouse Brain. Analytical Chemistry. 88: 12137-12144. PMID 28193056 DOI: 10.1021/Acs.Analchem.6B02947 |
0.307 |
|
| 2016 |
Chen YJ, Mahieu NG, Huang X, Singh M, Crawford PA, Johnson SL, Gross RW, Schaefer J, Patti GJ. Lactate metabolism is associated with mammalian mitochondria. Nature Chemical Biology. PMID 27618187 DOI: 10.1038/Nchembio.2172 |
0.385 |
|
| 2016 |
Aubert G, Martin OJ, Horton JL, Lai L, Vega RB, Leone TC, Koves T, Gardell SJ, Krüger M, Hoppel CL, Lewandowski ED, Crawford PA, Muoio DM, Kelly DP. The Failing Heart Relies on Ketone Bodies as a Fuel. Circulation. PMID 26819376 DOI: 10.1161/Circulationaha.115.017355 |
0.301 |
|
| 2015 |
Youm YH, Nguyen KY, Grant RW, Goldberg EL, Bodogai M, Kim D, D'Agostino D, Planavsky N, Lupfer C, Kanneganti TD, Kang S, Horvath TL, Fahmy TM, Crawford PA, Biragyn A, et al. The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Nature Medicine. 21: 263-9. PMID 25686106 DOI: 10.1038/Nm.3804 |
0.386 |
|
| 2014 |
Schugar RC, Moll AR, André d'Avignon D, Weinheimer CJ, Kovacs A, Crawford PA. Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling. Molecular Metabolism. 3: 754-69. PMID 25353003 DOI: 10.1016/J.Molmet.2014.07.010 |
0.754 |
|
| 2014 |
Cotter DG, Ercal B, Huang X, Leid JM, d'Avignon DA, Graham MJ, Dietzen DJ, Brunt EM, Patti GJ, Crawford PA. Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia. The Journal of Clinical Investigation. 124: 5175-90. PMID 25347470 DOI: 10.1172/Jci76388 |
0.731 |
|
| 2014 |
Cotter DG, Ercal B, d'Avignon DA, Dietzen DJ, Crawford PA. Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice. American Journal of Physiology. Endocrinology and Metabolism. 307: E176-85. PMID 24865983 DOI: 10.1152/Ajpendo.00087.2014 |
0.725 |
|
| 2014 |
Cotter D, Ercal B, Leid J, d'Avignon DA, Graham M, Dietzen D, Brunt E, Crawford P. Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia through coenzyme A recycling (LB769) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.Lb769 |
0.715 |
|
| 2013 |
Chambers KT, Chen Z, Lai L, Leone TC, Towle HC, Kralli A, Crawford PA, Finck BN. PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner. Molecular Metabolism. 2: 194-204. PMID 24049734 DOI: 10.1016/J.Molmet.2013.05.001 |
0.367 |
|
| 2013 |
Schugar RC, Huang X, Moll AR, Brunt EM, Crawford PA. Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet. Plos One. 8: e74806. PMID 24009777 DOI: 10.1371/Journal.Pone.0074806 |
0.766 |
|
| 2013 |
Cotter DG, Ercal B, d'Avignon DA, Dietzen DJ, Crawford PA. Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth. The Journal of Biological Chemistry. 288: 19739-49. PMID 23689508 DOI: 10.1074/Jbc.M113.454868 |
0.736 |
|
| 2013 |
Cotter DG, Schugar RC, Crawford PA. Ketone body metabolism and cardiovascular disease. American Journal of Physiology. Heart and Circulatory Physiology. 304: H1060-76. PMID 23396451 DOI: 10.1152/Ajpheart.00646.2012 |
0.766 |
|
| 2013 |
Cotter DG, Schugar RC, Wentz AE, d'Avignon DA, Crawford PA. Successful adaptation to ketosis by mice with tissue-specific deficiency of ketone body oxidation. American Journal of Physiology. Endocrinology and Metabolism. 304: E363-74. PMID 23233542 DOI: 10.1152/Ajpendo.00547.2012 |
0.785 |
|
| 2013 |
Crawford PA, Schaffer JE. Metabolic stress in the myocardium: adaptations of gene expression. Journal of Molecular and Cellular Cardiology. 55: 130-8. PMID 22728216 DOI: 10.1016/J.Yjmcc.2012.06.008 |
0.386 |
|
| 2012 |
Chambers KT, Chen Z, Crawford PA, Fu X, Burgess SC, Lai L, Leone TC, Kelly DP, Finck BN. Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding. Plos One. 7: e52645. PMID 23285128 DOI: 10.1371/Journal.Pone.0052645 |
0.521 |
|
| 2012 |
Schugar RC, Crawford PA. Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease. Current Opinion in Clinical Nutrition and Metabolic Care. 15: 374-80. PMID 22617564 DOI: 10.1097/Mco.0B013E3283547157 |
0.746 |
|
| 2011 |
Garbow JR, Doherty JM, Schugar RC, Travers S, Weber ML, Wentz AE, Ezenwajiaku N, Cotter DG, Brunt EM, Crawford PA. Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G956-67. PMID 21454445 DOI: 10.1152/Ajpgi.00539.2010 |
0.783 |
|
| 2011 |
Cotter DG, d'Avignon DA, Wentz AE, Weber ML, Crawford PA. Obligate role for ketone body oxidation in neonatal metabolic homeostasis. The Journal of Biological Chemistry. 286: 6902-10. PMID 21209089 DOI: 10.1074/Jbc.M110.192369 |
0.734 |
|
| 2010 |
Etzion S, Etzion Y, DeBosch B, Crawford PA, Muslin AJ. Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity. Journal of Molecular and Cellular Cardiology. 49: 931-40. PMID 20728450 DOI: 10.1016/J.Yjmcc.2010.08.011 |
0.386 |
|
| 2010 |
Wentz AE, d'Avignon DA, Weber ML, Cotter DG, Doherty JM, Kerns R, Nagarajan R, Reddy N, Sambandam N, Crawford PA. Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment. The Journal of Biological Chemistry. 285: 24447-56. PMID 20529848 DOI: 10.1074/Jbc.M110.100651 |
0.771 |
|
| 2010 |
Bäckhed F, Crawford PA. Coordinated regulation of the metabolome and lipidome at the host-microbial interface. Biochimica Et Biophysica Acta. 1801: 240-5. PMID 19782151 DOI: 10.1016/J.Bbalip.2009.09.009 |
0.367 |
|
| 2009 |
Crawford PA, Crowley JR, Sambandam N, Muegge BD, Costello EK, Hamady M, Knight R, Gordon JI. Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation. Proceedings of the National Academy of Sciences of the United States of America. 106: 11276-81. PMID 19549860 DOI: 10.1073/Pnas.0902366106 |
0.785 |
|
| 2008 |
Mouillet JF, Yan X, Ou Q, Jin L, Muglia LJ, Crawford PA, Sadovsky Y. DEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and function. Endocrinology. 149: 2168-75. PMID 18258677 DOI: 10.1210/En.2007-1237 |
0.365 |
|
| 2007 |
Bäckhed F, Crawford PA, O'Donnell D, Gordon JI. Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor. Proceedings of the National Academy of Sciences of the United States of America. 104: 606-11. PMID 17202268 DOI: 10.1073/Pnas.0605957104 |
0.493 |
|
| 2005 |
Crawford PA, Gordon JI. Microbial regulation of intestinal radiosensitivity. Proceedings of the National Academy of Sciences of the United States of America. 102: 13254-9. PMID 16129828 DOI: 10.1073/Pnas.0504830102 |
0.538 |
|
| 1998 |
Crawford PA, Dorn C, Sadovsky Y, Milbrandt J. Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1. Molecular and Cellular Biology. 18: 2949-56. PMID 9566914 DOI: 10.1128/Mcb.18.5.2949 |
0.491 |
|
| 1998 |
Sadovsky Y, Crawford PA. Developmental and physiologic roles of the nuclear receptor steroidogenic factor-1 in the reproductive system. Journal of the Society For Gynecologic Investigation. 5: 6-12. PMID 9501292 DOI: 10.1016/S1071-5576(97)00096-8 |
0.336 |
|
| 1997 |
Chau YM, Crawford PA, Woodson KG, Polish JA, Olson LM, Sadovsky Y. Role of steroidogenic-factor 1 in basal and 3',5'-cyclic adenosine monophosphate-mediated regulation of cytochrome P450 side-chain cleavage enzyme in the mouse. Biology of Reproduction. 57: 765-71. PMID 9314578 DOI: 10.1095/Biolreprod57.4.765 |
0.311 |
|
| 1997 |
Crawford PA, Sadovsky Y, Milbrandt J. Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineage. Molecular and Cellular Biology. 17: 3997-4006. PMID 9199334 DOI: 10.1128/Mcb.17.7.3997 |
0.503 |
|
| 1997 |
Woodson KG, Crawford PA, Sadovsky Y, Milbrandt J. Characterization of the promoter of SF-1, an orphan nuclear receptor required for adrenal and gonadal development. Molecular Endocrinology (Baltimore, Md.). 11: 117-26. PMID 9013759 DOI: 10.1210/Mend.11.2.9881 |
0.464 |
|
| 1995 |
Crawford PA, Sadovsky Y, Woodson K, Lee SL, Milbrandt J. Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice. Molecular and Cellular Biology. 15: 4331-16. PMID 7623827 DOI: 10.1128/Mcb.15.8.4331 |
0.536 |
|
| 1995 |
Sadovsky Y, Crawford PA, Woodson KG, Polish JA, Clements MA, Tourtellotte LM, Simburger K, Milbrandt J. Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids. Proceedings of the National Academy of Sciences of the United States of America. 92: 10939-43. PMID 7479914 DOI: 10.1073/Pnas.92.24.10939 |
0.547 |
|
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