Niall G. Howlett - Publications

Affiliations: 
Cell & Molecular Biology University of Rhode Island, Providence, RI, United States 
Area:
Cell Biology, Biogeochemistry, Genetics, Oncology

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Blaize JL, Noori BM, Hunter KP, Henrickson KA, Atoyan JA, Ardito AA, Donovan FX, Chandrasekharappa SC, Schindler D, Howlett NG. Differential regulation of Retinoic Acid Metabolism in Fanconi Anemia. Biorxiv : the Preprint Server For Biology. PMID 37066159 DOI: 10.1101/2023.04.06.535759  0.438
2021 Cantres-Velez JA, Blaize JL, Vierra DA, Boisvert RA, Garzon JL, Piraino B, Tan W, Deans AJ, Howlett NG. CDK-Mediated Phosphorylation of FANCD2 Promotes Mitotic Fidelity. Molecular and Cellular Biology. MCB0023421. PMID 34096775 DOI: 10.1128/MCB.00234-21  0.41
2020 Shao X, Joergensen AM, Howlett NG, Lisby M, Oestergaard VH. A distinct role for recombination repair factors in an early cellular response to transcription-replication conflicts. Nucleic Acids Research. PMID 32329774 DOI: 10.1093/Nar/Gkaa268  0.494
2019 Paquin KL, Mamrak NE, Garzon JL, Cantres-Velez JA, Azzinaro PA, Vuono EA, Lima KE, Camberg JL, Howlett NG. FANCD2 binding to H4K20me2 a methyl-binding domain is essential for efficient DNA crosslink repair. Molecular and Cellular Biology. PMID 31085681 DOI: 10.1128/Mcb.00194-19  0.523
2018 Higgs MR, Sato K, Reynolds JJ, Begum S, Bayley R, Goula A, Vernet A, Paquin KL, Skalnik DG, Kobayashi W, Takata M, Howlett NG, Kurumizaka H, Kimura H, Stewart GS. Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2. Molecular Cell. PMID 29937342 DOI: 10.1016/J.Molcel.2018.05.018  0.475
2018 Paquin KL, Howlett NG. Understanding the histone DNA repair code: H4K20me2 makes its mark. Molecular Cancer Research : McR. PMID 29858375 DOI: 10.1158/1541-7786.Mcr-17-0688  0.541
2017 Vierra DA, Garzon JL, Rego MA, Adroved MM, Mauro M, Howlett NG. Modulation of the Fanconi anemia pathway via chemically induced changes in chromatin structure. Oncotarget. 8: 76443-76457. PMID 29100324 DOI: 10.18632/Oncotarget.19470  0.732
2017 Vierra DA, Garzon JL, Rego MA, Adroved MM, Mauro M, Howlett NG. Modulation of the Fanconi anemia pathway via chemically induced changes in chromatin structure. Oncotarget. PMID 28778076 DOI: 10.18632/oncotarget.19470  0.726
2016 Vuono EA, Mukherjee A, Vierra DA, Adroved MM, Hodson C, Deans AJ, Howlett NG. The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair. Scientific Reports. 6: 36439. PMID 27819275 DOI: 10.1038/Srep36439  0.609
2016 Madireddy A, Kosiyatrakul ST, Boisvert RA, Herrera-Moyano E, García-Rubio ML, Gerhardt J, Vuono EA, Owen N, Yan Z, Olson S, Aguilera A, Howlett NG, Schildkraut CL. FANCD2 Facilitates Replication through Common Fragile Sites. Molecular Cell. 64: 388-404. PMID 27768874 DOI: 10.1016/J.Molcel.2016.09.017  0.407
2016 Mamrak NE, Shimamura A, Howlett NG. Recent discoveries in the molecular pathogenesis of the inherited bone marrow failure syndrome Fanconi anemia. Blood Reviews. PMID 27760710 DOI: 10.1016/J.Blre.2016.10.002  0.451
2016 Stanley EC, Azzinaro PA, Vierra DA, Howlett NG, Irvine SQ. The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia. Evolutionary Bioinformatics Online. 12: 133-48. PMID 27279728 DOI: 10.4137/Ebo.S37920  0.423
2014 Boisvert RA, Howlett NG. The Fanconi anemia ID2 complex: dueling saxes at the crossroads. Cell Cycle (Georgetown, Tex.). 13: 2999-3015. PMID 25486561 DOI: 10.4161/15384101.2014.956475  0.581
2013 Boisvert RA, Rego MA, Azzinaro PA, Mauro M, Howlett NG. Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal. Plos One. 8: e81387. PMID 24278431 DOI: 10.1371/Journal.Pone.0081387  0.73
2013 Mukherjee A, Misra S, Howlett NG, Karmakar P. Multinucleation regulated by the Akt/PTEN signaling pathway is a survival strategy for HepG2 cells. Mutation Research. 755: 135-40. PMID 23796964 DOI: 10.1016/J.Mrgentox.2013.06.009  0.359
2012 Rego MA, Kolling FW, Vuono EA, Mauro M, Howlett NG. Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein. Blood. 120: 2109-17. PMID 22855611 DOI: 10.1182/Blood-2012-02-410472  0.72
2012 Mauro M, Rego MA, Boisvert RA, Esashi F, Cavallo F, Jasin M, Howlett NG. p21 promotes error-free replication-coupled DNA double-strand break repair. Nucleic Acids Research. 40: 8348-60. PMID 22735704 DOI: 10.1093/Nar/Gks612  0.736
2012 Rego MA, Harney JA, Mauro M, Shen M, Howlett NG. Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor. Oncogene. 31: 366-75. PMID 21685936 DOI: 10.1038/Onc.2011.237  0.764
2011 Cybulski KE, Howlett NG. FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair. Cell Cycle (Georgetown, Tex.). 10: 1757-63. PMID 21527828 DOI: 10.4161/Cc.10.11.15818  0.538
2010 Hicks JK, Chute CL, Paulsen MT, Ragland RL, Howlett NG, Guéranger Q, Glover TW, Canman CE. Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. Molecular and Cellular Biology. 30: 1217-30. PMID 20028736 DOI: 10.1128/Mcb.00993-09  0.531
2010 Rego MA, Mauro M, Harney JA, Shen M, Kolling FW, Howlett NG. Abstract LB-102: The p21Cip1/Waf1cyclin-dependent kinase inhibitor is required for the activation of the FA-BRCA pathway Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-102  0.724
2009 Howlett NG, Harney JA, Rego MA, Kolling FW, Glover TW. Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif. The Journal of Biological Chemistry. 284: 28935-42. PMID 19704162 DOI: 10.1074/Jbc.M109.016352  0.747
2009 Rego MA, Kolling FW, Howlett NG. The Fanconi anemia protein interaction network: casting a wide net. Mutation Research. 668: 27-41. PMID 19101576 DOI: 10.1016/J.Mrfmmm.2008.11.018  0.739
2008 Harney JA, Shimamura A, Howlett NG. Fanconi anemia: A multi-age cancer susceptibility syndrome Pediatric Health. 2: 175-187. DOI: 10.2217/17455111.2.2.175  0.492
2006 Durkin SG, Arlt MF, Howlett NG, Glover TW. Depletion of CHK1, but not CHK2, induces chromosomal instability and breaks at common fragile sites Oncogene. 25: 4381-4388. PMID 16732333 DOI: 10.1038/Sj.Onc.1209466  0.467
2006 Howlett NG, Scuric Z, D'Andrea AD, Schiestl RH. Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients. Dna Repair. 5: 251-7. PMID 16309973 DOI: 10.1016/J.Dnarep.2005.10.004  0.536
2005 Kirpnick Z, Homiski M, Rubitski E, Repnevskaya M, Howlett N, Aubrecht J, Schiestl RH. Yeast DEL assay detects clastogens. Mutation Research. 582: 116-34. PMID 15781217 DOI: 10.1016/J.Mrgentox.2005.01.005  0.359
2005 Howlett NG, Taniguchi T, Durkin SG, D'Andrea AD, Glover TW. The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability. Human Molecular Genetics. 14: 693-701. PMID 15661754 DOI: 10.1093/Hmg/Ddi065  0.581
2004 Secretan MB, Scuric Z, Oshima J, Bishop AJR, Howlett NG, Yau D, Schiestl RH. Effect of Ku86 and DNA-PKcs deficiency on non-homologous end-joining and homologous recombination using a transient transfection assay Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 554: 351-364. PMID 15450431 DOI: 10.1016/J.Mrfmmm.2004.05.016  0.507
2004 Howlett NG, Schiestl RH. Nucleotide excision repair deficiency causes elevated levels of chromosome gain in Saccharomyces cerevisiae. Dna Repair. 3: 127-34. PMID 14706346 DOI: 10.1016/J.Dnarep.2003.10.003  0.473
2003 Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D'Andrea AD, Look AT. Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis. Developmental Cell. 5: 903-14. PMID 14667412 DOI: 10.1016/S1534-5807(03)00339-3  0.456
2002 Vonarx EJ, Howlett NG, Schiestl RH, Kunz BA. Detection of Arabidopsis thaliana AtRAD1 cDNA variants and assessment of function by expression in a yeast rad1 mutant. Gene. 296: 1-9. PMID 12383497 DOI: 10.1016/S0378-1119(02)00869-7  0.368
2002 Howlett NG, Taniguchi T, Olson S, Cox B, Waisfisz Q, De Die-Smulders C, Persky N, Grompe M, Joenje H, Pals G, Ikeda H, Fox EA, D'Andrea AD. Biallelic inactivation of BRCA2 in Fanconi anemia. Science (New York, N.Y.). 297: 606-9. PMID 12065746 DOI: 10.1126/Science.1073834  0.405
2000 Howlett NG, Schiestl RH. Simultaneous measurement of the frequencies of intrachromosomal recombination and chromosome gain using the yeast DEL assay Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 454: 53-62. PMID 11035159 DOI: 10.1016/S0027-5107(00)00097-X  0.344
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