Debra A. Schwinn - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
molecular pharmacology, alpha 1 adrenergic receptors

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Gradinaru I, Babaeva E, Schwinn DA, Oganesian A. Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway. Plos One. 10: e0142787. PMID 26571308 DOI: 10.1371/Journal.Pone.0142787  0.33
2011 Oganesian A, Yarov-Yarovoy V, Parks WC, Schwinn DA. Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway. Proceedings of the National Academy of Sciences of the United States of America. 108: 19796-801. PMID 22089237 DOI: 10.1073/Pnas.1116271108  0.317
2011 von Homeyer P, Schwinn DA. Pharmacogenomics of β-adrenergic receptor physiology and response to β-blockade. Anesthesia and Analgesia. 113: 1305-18. PMID 21965354 DOI: 10.1213/Ane.0B013E31822B887E  0.34
2009 Lei B, Morris DP, Smith MP, Schwinn DA. Lipid rafts constrain basal alpha(1A)-adrenergic receptor signaling by maintaining receptor in an inactive conformation. Cellular Signalling. 21: 1532-9. PMID 19520158 DOI: 10.1016/J.Cellsig.2009.06.001  0.453
2008 Schwinn DA, Roehrborn CG. Alpha1-adrenoceptor subtypes and lower urinary tract symptoms. International Journal of Urology : Official Journal of the Japanese Urological Association. 15: 193-9. PMID 18304211 DOI: 10.1111/J.1442-2042.2007.01956.X  0.359
2008 Morris DP, Lei B, Wu YX, Michelotti GA, Schwinn DA. The alpha1a-adrenergic receptor occupies membrane rafts with its G protein effectors but internalizes via clathrin-coated pits. The Journal of Biological Chemistry. 283: 2973-85. PMID 18048357 DOI: 10.1074/Jbc.M705795200  0.431
2007 Stafford-Smith M, Bartz R, Wilson K, Baraniuk JN, Schwinn DA. Alpha-adrenergic mRNA subtype expression in the human nasal turbinate. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthã©Sie. 54: 549-55. PMID 17602041 DOI: 10.1007/Bf03022319  0.394
2007 Michelotti GA, Brinkley DM, Morris DP, Smith MP, Louie RJ, Schwinn DA. Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1979-93. PMID 17384146 DOI: 10.1096/Fj.06-7118Com  0.312
2007 Schwinn DA. IL-8 α1-Adrenergic Receptors and LUTS The Japanese Journal of Urology. 98: 61. DOI: 10.5980/Jpnjurol.98.61  0.315
2006 Schwinn DA, Afshari NA. alpha(1)-Adrenergic receptor antagonists and the iris: new mechanistic insights into floppy iris syndrome. Survey of Ophthalmology. 51: 501-12. PMID 16950249 DOI: 10.1016/j.survophthal.2006.06.011  0.315
2006 Podgoreanu MV, White WD, Morris RW, Mathew JP, Stafford-Smith M, Welsby IJ, Grocott HP, Milano CA, Newman MF, Schwinn DA. Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. Circulation. 114: I275-81. PMID 16820586 DOI: 10.1161/Circulationaha.105.001032  0.463
2006 Morris D, Schwinn D, Michelotti G. Adrenergic receptor alpha 1a Afcs-Nature Molecule Pages. DOI: 10.1038/Mp.A000007.01  0.44
2005 Diaw L, Roth M, Schwinn DA, d'Alelio ME, Green LJ, Tangrea JA. Characteristics of a human prostate stromal cell line related to its use in a stromal-epithelial coculture model for the study of cancer chemoprevention. In Vitro Cellular & Developmental Biology. Animal. 41: 142-8. PMID 16153146 DOI: 10.1290/0412079.1  0.333
2005 Schambra UB, Mackensen GB, Stafford-Smith M, Haines DE, Schwinn DA. Neuron specific alpha-adrenergic receptor expression in human cerebellum: implications for emerging cerebellar roles in neurologic disease. Neuroscience. 135: 507-23. PMID 16112482 DOI: 10.1016/J.Neuroscience.2005.06.021  0.468
2005 Lei B, Morris DP, Smith MP, Svetkey LP, Newman MF, Rotter JI, Buchanan TA, Beckstrom-Sternberg SM, Green ED, Schwinn DA. Novel human alpha1a-adrenoceptor single nucleotide polymorphisms alter receptor pharmacology and biological function. Naunyn-Schmiedeberg's Archives of Pharmacology. 371: 229-39. PMID 15900517 DOI: 10.1007/S00210-005-1019-9  0.432
2005 Stafford-Smith M, Podgoreanu M, Swaminathan M, Phillips-Bute B, Mathew JP, Hauser EH, Winn MP, Milano C, Nielsen DM, Smith M, Morris R, Newman MF, Schwinn DA. Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 45: 519-30. PMID 15754274 DOI: 10.1053/J.Ajkd.2004.11.021  0.462
2004 Hawrylyshyn KA, Michelotti GA, Cogé F, Guénin SP, Schwinn DA. Update on human alpha1-adrenoceptor subtype signaling and genomic organization. Trends in Pharmacological Sciences. 25: 449-55. PMID 15559245 DOI: 10.1016/J.Tips.2004.06.011  0.425
2004 Schwinn DA, Price DT, Narayan P. alpha1-Adrenoceptor subtype selectivity and lower urinary tract symptoms. Mayo Clinic Proceedings. 79: 1423-34. PMID 15544022 DOI: 10.4065/79.11.1423  0.324
2004 Michelotti GA, Schwinn DA. Mechanistic insights into the role of alpha1adrenergic receptors in lower urinary tract symptoms. Current Urology Reports. 5: 258-66. PMID 15260925  0.309
2004 Morris DP, Price RR, Smith MP, Lei B, Schwinn DA. Cellular trafficking of human alpha1a-adrenergic receptors is continuous and primarily agonist-independent. Molecular Pharmacology. 66: 843-54. PMID 15258254 DOI: 10.1124/Mol.104.000430  0.366
2004 Gu B, Reiter JP, Schwinn DA, Smith MP, Korstanje C, Thor KB, Dolber PC. Effects of alpha 1-adrenergic receptor subtype selective antagonists on lower urinary tract function in rats with bladder outlet obstruction. The Journal of Urology. 172: 758-62. PMID 15247777 DOI: 10.1097/01.Ju.0000131609.96301.E6  0.421
2004 Booth JV, Ward EE, Colgan KC, Funk BL, El-Moalem H, Smith MP, Milano C, Smith PK, Newman MF, Schwinn DA. Metoprolol and coronary artery bypass grafting surgery: does intraoperative metoprolol attenuate acute beta-adrenergic receptor desensitization during cardiac surgery? Anesthesia and Analgesia. 98: 1224-31, table of co. PMID 15105192 DOI: 10.1213/01.Ane.0000112325.66981.03  0.527
2004 Roehrborn CG, Schwinn DA. Alpha1-adrenergic receptors and their inhibitors in lower urinary tract symptoms and benign prostatic hyperplasia. The Journal of Urology. 171: 1029-35. PMID 14767264 DOI: 10.1097/01.Ju.0000097026.43866.Cc  0.397
2004 Schwinn DA, Duke JB. New advances in receptor pharmacology Revista Mexicana De Anestesiologia. 27: S85-S89. DOI: 10.1097/00001503-199108000-00004  0.376
2004 Michelotti GA, Schwinn DA. Mechanistic insights into the role of α1-adrenergic receptors in lower urinary tract symptoms Current Prostate Reports. 2: 78-86. DOI: 10.1007/S11918-004-0005-X  0.32
2003 Lee TW, Grocott HP, Schwinn D, Jacobsohn E. High spinal anesthesia for cardiac surgery: effects on beta-adrenergic receptor function, stress response, and hemodynamics. Anesthesiology. 98: 499-510. PMID 12552211 DOI: 10.1097/00000542-200302000-00032  0.367
2003 Hagen SA, Kondyra AL, Grocott HP, El-Moalem H, Bainbridge D, Mathew JP, Newman MF, Reves JG, Schwinn DA, Kwatra MM. Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells. Anesthesiology. 98: 343-8. PMID 12552191 DOI: 10.1097/00000542-200302000-00012  0.656
2003 Michelotti GA, Bauman MJ, Smith MP, Schwinn DA. Cloning and characterization of the rat alpha 1a-adrenergic receptor gene promoter. Demonstration of cell specificity and regulation by hypoxia. The Journal of Biological Chemistry. 278: 8693-705. PMID 12471020 DOI: 10.1074/Jbc.M211986200  0.393
2002 Booth JV, Spahn DR, McRae RL, Chesnut LC, El-Moalem H, Atwell DM, Leone BJ, Schwinn DA. Esmolol improves left ventricular function via enhanced beta-adrenergic receptor signaling in a canine model of coronary revascularization. Anesthesiology. 97: 162-9. PMID 12131118 DOI: 10.1097/00000542-200207000-00023  0.361
2002 Swaminathan M, McCreath BJ, Phillips-Bute BG, Newman MF, Mathew JP, Smith PK, Blumenthal JA, Stafford-Smith M, Grocott HP, Hill SE, Reves JG, Schwinn DA, Warner D, Harris M, Kirchner JL, et al. Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction Anesthesia and Analgesia. 95: 1-8. PMID 12088934 DOI: 10.1097/00000539-200207000-00001  0.617
2002 Amory DW, Grigore A, Amory JK, Gerhardt MA, White WD, Smith PK, Schwinn DA, Reves JG, Newman MF. Neuroprotection is associated with beta-adrenergic receptor antagonists during cardiac surgery: evidence from 2,575 patients. Journal of Cardiothoracic and Vascular Anesthesia. 16: 270-7. PMID 12073195 DOI: 10.1053/jcan.2002.124132  0.312
2002 Price RR, Morris DP, Biswas G, Smith MP, Schwinn DA. Acute agonist-mediated desensitization of the human alpha 1a-adrenergic receptor is primarily independent of carboxyl terminus regulation: implications for regulation of alpha 1aAR splice variants. The Journal of Biological Chemistry. 277: 9570-9. PMID 11781325 DOI: 10.1074/Jbc.M111762200  0.436
2002 Grigore AM, Grocott HP, Mathew JP, Phillips-Bute B, Stanley TO, Butler A, Landolfo KP, Reves JG, Blumenthal JA, Newman MF, Clements FM, De Bruijn N, Grichnik K, Hill SE, Hilton AK, ... Schwinn DA, et al. The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery Anesthesia and Analgesia. 94: 4-10. PMID 11772792 DOI: 10.1097/00000539-200201000-00002  0.508
2002 Hampel C, Dolber PC, Smith MP, Savic SL, Thüroff JW, Thor KB, Schwinn DA. Modulation of bladder α1-adrenergic receptor subtype expression by bladder outlet obstruction The Journal of Urology. 167: 1513-1521. DOI: 10.1016/S0022-5347(05)65355-4  0.332
2001 Schwinn DA. The role of alpha1-adrenergic receptor subtypes in lower urinary tract symptoms. Bju International. 88: 27-34; discussion 49. PMID 11589667 DOI: 10.1046/j.1464-410X.2001.00116.x  0.316
2000 Schwinn DA. Novel role for alpha1-adrenergic receptor subtypes in lower urinary tract symptoms. Bju International. 86: 11-20; discussion 20. PMID 11501613 DOI: 10.1046/j.1464-410X.2000.00098.x  0.319
2000 Michelotti GA, Price DT, Schwinn DA. Alpha 1-adrenergic receptor regulation: basic science and clinical implications. Pharmacology & Therapeutics. 88: 281-309. PMID 11337028 DOI: 10.1016/S0163-7258(00)00092-9  0.474
2000 Price DT, Rudner X, Michelotti GA, Schwinn DA. Immortalization of a human prostate stromal cell line using a recombinant retroviral approach. The Journal of Urology. 164: 2145-50. PMID 11061945 DOI: 10.1016/S0022-5347(05)66987-X  0.351
2000 Shapiro RE, Winters B, Hales M, Barnett T, Schwinn DA, Flavahan N, Berkowitz DE. Endogenous circulating sympatholytic factor in orthostatic intolerance. Hypertension. 36: 553-60. PMID 11040235 DOI: 10.1161/01.Hyp.36.4.553  0.398
2000 Kilts JD, Gerhardt MA, Richardson MD, Sreeram G, Mackensen GB, Grocott HP, White WD, Davis RD, Newman MF, Reves JG, Schwinn DA, Kwatra MM. Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i). Circulation Research. 87: 705-9. PMID 11029407 DOI: 10.1161/01.Res.87.8.705  0.413
2000 Ongioco RR, Richardson CD, Rudner XL, Stafford-Smith M, Schwinn DA. Alpha2-adrenergic receptors in human dorsal root ganglia: predominance of alpha2b and alpha2c subtype mRNAs. Anesthesiology. 92: 968-76. PMID 10754615 DOI: 10.1097/00000542-200004000-00013  0.357
2000 Smith MS, Schwinn DA. In situ hybridization of adrenergic receptor mRNA in brain. Methods in Molecular Biology (Clifton, N.J.). 126: 519-33. PMID 10685433 DOI: 10.1385/1-59259-684-3:519  0.336
1999 Rudner XL, Berkowitz DE, Booth JV, Funk BL, Cozart KL, D'Amico EB, El-Moalem H, Page SO, Richardson CD, Winters B, Marucci L, Schwinn DA. Subtype specific regulation of human vascular alpha(1)-adrenergic receptors by vessel bed and age. Circulation. 100: 2336-43. PMID 10587338 DOI: 10.1161/01.Cir.100.23.2336  0.429
1999 Goepel M, Krege S, Price DT, Michelotti GA, Schwinn DA, Michel MC. Characterization of alpha-adrenoceptor subtypes in the corpus cavernosum of patients undergoing sex change surgery. The Journal of Urology. 162: 1793-9. PMID 10524937 DOI: 10.1016/S0022-5347(05)68240-7  0.39
1999 Price DT, Della Rocca G, Guo C, Ballo MS, Schwinn DA, Luttrell LM. Activation of extracellular signal-regulated kinase in human prostate cancer. The Journal of Urology. 162: 1537-42. PMID 10492251 DOI: 10.1016/S0022-5347(05)68354-1  0.527
1999 Schwinn DA, Price RR. Molecular pharmacology of human alpha1-adrenergic receptors: unique features of the alpha 1a-subtype. European Urology. 36: 7-10. PMID 10393466 DOI: 10.1159/000052311  0.43
1999 Debruyne FMJ, Poel HGvd, Groat WCd, Yoshiyama M, Ramage AG, Yamamoto T, Somogyi GT, Brading AF, McCoy R, Dass N, McGrath JC, Naghadeh MA, Pediani JD, Mackenzie JF, Daly CJ, ... ... Schwinn DA, et al. Abstracts, Poster Session European Urology. 36: 113-117. DOI: 10.1159/000052331  0.517
1999 Garduno C, Phillips-Bute B, Funk B, Schwinn D, Smith MS. PERIOPERATIVE RENAL DYSFUNCTION IN CARDIAC SURGICAL PATIENTS beta ADRENERGIC RECEPTOR BLOCKADE DOES NOT INFLUENCE Anesthesia & Analgesia. 88: 90SCA. DOI: 10.1097/00000539-199904001-00090  0.378
1999 Rudner X, Berkowitz D, Cozart K, Marucci L, Schwinn D. alpha1 AR-MEDIATED CONTRACTION IN HUMAN MAMMARY ARTERY IS MEDIATED BY alpha1a and alpha1b AR SUBTYPES Anesthesia & Analgesia. 88: 50SCA. DOI: 10.1097/00000539-199904001-00050  0.404
1998 Lee K, Richardson CD, Razik MA, Kwatra MM, Schwinn DA. Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor. Dna Sequence : the Journal of Dna Sequencing and Mapping. 8: 271-6. PMID 10520459 DOI: 10.3109/10425179809008464  0.426
1998 Booth JV, Landolfo KP, Chesnut LC, Bennett-Guerrero E, Gerhardt MA, Atwell DM, El-Moalem HE, Smith MS, Funk BL, Kuhn CM, Kwatra MM, Schwinn DA. Acute depression of myocardial beta-adrenergic receptor signaling during cardiopulmonary bypass: impairment of the adenylyl cyclase moiety. Duke Heart Center Perioperative Desensitization Group. Anesthesiology. 89: 602-11. PMID 9743395 DOI: 10.1097/00000542-199809000-00008  0.349
1998 Malloy BJ, Price DT, Price RR, Bienstock AM, Dole MK, Funk BL, Rudner XL, Richardson CD, Donatucci CF, Schwinn DA. Alpha1-adrenergic receptor subtypes in human detrusor. The Journal of Urology. 160: 937-43. PMID 9720591 DOI: 10.1016/S0022-5347(01)62836-2  0.48
1998 Smiley RM, Kwatra MM, Schwinn DA. New developments in cardiovascular adrenergic receptor pharmacology: molecular mechanisms and clinical relevance. Journal of Cardiothoracic and Vascular Anesthesia. 12: 80-95. PMID 9509364 DOI: 10.1016/S1053-0770(98)90062-3  0.384
1998 Scanga DR, Schwinn DA. Transcriptional regulation of alpha-1 adrenergic receptors. Frontiers in Bioscience : a Journal and Virtual Library. 3: d348-53. PMID 9497274 DOI: 10.2741/A279  0.446
1998 Nishimura K, Warabi K, Roush ED, Frederick J, Schwinn DA, Kwatra MM. Characterization of GRK2-catalyzed phosphorylation of the human substance P receptor in Sf9 membranes. Biochemistry. 37: 1192-8. PMID 9477943 DOI: 10.1021/Bi972302S  0.37
1998 Schwinn DA, Kwatra MM. Expression and regulation of alpha 1-adrenergic receptors in human tissues. Advances in Pharmacology (San Diego, Calif.). 42: 390-4. PMID 9327922  0.341
1998 Gerhardt MA, Barnett TN, Barry WT, Schwinn DA, Kwatra MM. [Greek small letter beta]2-ADRENERGIC RECEPTORS IN HUMAN ATRIAL MEMBRANES ACTIVATE BOTH Gs AND Gi Anesthesiology. 89: 206A. DOI: 10.1097/00000542-199809050-00018  0.374
1997 Razik MA, Lee K, Price RR, Williams MR, Ongjoco RR, Dole MK, Rudner XL, Kwatra MM, Schwinn DA. Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region. The Journal of Biological Chemistry. 272: 28237-46. PMID 9353275 DOI: 10.1074/Jbc.272.45.28237  0.303
1997 Richardson CD, Donatucci CF, Page SO, Wilson KH, Schwinn DA. Pharmacology of tamsulosin: saturation-binding isotherms and competition analysis using cloned alpha 1-adrenergic receptor subtypes. The Prostate. 33: 55-9. PMID 9294627 DOI: 10.1002/(Sici)1097-0045(19970915)33:1<55::Aid-Pros9>3.0.Co;2-8  0.456
1997 Tan JP, Seidler FJ, Schwinn DA, Page SO, Slotkin TA. A critical period for the role of thyroid hormone in development of renal alpha-adrenergic receptors. Pediatric Research. 42: 93-102. PMID 9212043 DOI: 10.1203/00006450-199707000-00015  0.431
1997 Kirshbom PM, Page SO, Jacobs MT, Tsui SS, Bello E, Ungerleider RM, Schwinn DA, Gaynor JW. Cardiopulmonary bypass and circulatory arrest increase endothelin-1 production and receptor expression in the lung. The Journal of Thoracic and Cardiovascular Surgery. 113: 777-83. PMID 9104988 DOI: 10.1016/S0022-5223(97)70237-X  0.334
1997 Smith MS, Baraniuk J, Schwinn D. A1078 alpha sub 2-ADRENERGIC RECEPTOR SUBTYPES IN HUMAN NASAL TURBINATE Anesthesiology. 87: 1078A. DOI: 10.1097/00000542-199709001-01078  0.435
1997 Roush ED, Schwinn DA, Kwatra MM. A640 Human Substance P Receptor Stably Expressed in CHO Cells Undet Agonist-Dependent Phosphorylation in vivo Anesthesiology. 87: 640A. DOI: 10.1097/00000542-199709001-00640  0.35
1997 Gerhardt &, Chesnut L, Funk B, Landolfo K, Schwinn D. A595 ACUTE MYOCARDIAL beta-ADERNERGIC RECEPTOR DESENSITIZATION DURING CARDIOPULMONARY BYPASS IN PATIENTS WITH CARDIAC VALVE DISEASE Anesthesiology. 87: 595A. DOI: 10.1097/00000542-199709001-00595  0.365
1997 Richardson C, Landolfo K, Kwatra MM, Schwinn DA. A100 Subtype Specific RT-PCR Quantitation of G Protein-Coupled Receptor Kinases in the Human Heart Anesthesiology. 87: 100A. DOI: 10.1097/00000542-199709001-00100  0.341
1997 Schwinn DA, Kwatra MM. α1,-Adrenoceptor Subtypes in the Human Cardiovascular and Urogenital Systems Advances in Pharmacology. 42: 390-394. DOI: 10.1016/S1054-3589(08)60771-1  0.316
1996 Lacey JP, Donatucci CF, Price DT, Page SO, Bennett SA, Tenniswood MP, Schwinn DA. Effects of androgen deprivation on prostate alpha 1-adrenergic receptors. Urology. 48: 335-41. PMID 8753753 DOI: 10.1016/S0090-4295(96)00183-5  0.401
1996 Berkowitz DE, Richardson C, Elliott DA, Leslie JB, Schwinn DA. Hypotension resistant to therapy with alpha receptor agonists complicating cardiopulmonary bypass: lithium as a potential cause. Anesthesia and Analgesia. 82: 1082-5. PMID 8610874 DOI: 10.1097/00000539-199605000-00038  0.413
1995 Smith MS, Schambra UB, Wilson KH, Page SO, Hulette C, Light AR, Schwinn DA. alpha 2-Adrenergic receptors in human spinal cord: specific localized expression of mRNA encoding alpha 2-adrenergic receptor subtypes at four distinct levels. Brain Research. Molecular Brain Research. 34: 109-17. PMID 8750866 DOI: 10.1016/0169-328X(95)00148-L  0.397
1995 Kwatra MM, Schreurs J, Schwinn DA, Innis MA, Caron MG, Lefkowitz RJ. Immunoaffinity purification of epitope-tagged human beta 2-adrenergic receptor to homogeneity. Protein Expression and Purification. 6: 717-21. PMID 8746622 DOI: 10.1006/Prep.1995.0001  0.63
1995 Schwinn DA, Johnston GI, Page SO, Mosley MJ, Wilson KH, Worman NP, Campbell S, Fidock MD, Furness LM, Parry-Smith DJ. Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. The Journal of Pharmacology and Experimental Therapeutics. 272: 134-42. PMID 7815325  0.344
1995 Berkowitz DE, Nardone NA, Smiley RM, Price DT, Kreutter DK, Fremeau RT, Schwinn DA. Distribution of beta 3-adrenoceptor mRNA in human tissues. European Journal of Pharmacology. 289: 223-8. PMID 7621895 DOI: 10.1016/0922-4106(95)90098-5  0.322
1995 Michel MC, Kenny B, Schwinn DA. Classification of alpha 1-adrenoceptor subtypes. Naunyn-Schmiedeberg's Archives of Pharmacology. 352: 1-10. PMID 7477417 DOI: 10.1007/Bf00169183  0.395
1994 Price DT, Lefkowitz RJ, Caron MG, Berkowitz D, Schwinn DA. Localization of mRNA for three distinct alpha 1-adrenergic receptor subtypes in human tissues: implications for human alpha-adrenergic physiology. Molecular Pharmacology. 45: 171-5. PMID 8114668  0.315
1994 Price DT, Chari RS, Berkowitz DE, Meyers WC, Schwinn DA. Expression of alpha 1-adrenergic receptor subtype mRNA in rat tissues and human SK-N-MC neuronal cells: implications for alpha 1-adrenergic receptor subtype classification. Molecular Pharmacology. 46: 221-6. PMID 8078485  0.309
1994 Berkowitz DE, Price DT, Bello EA, Page SO, Schwinn DA. Localization of messenger RNA for three distinct alpha 2-adrenergic receptor subtypes in human tissues. Evidence for species heterogeneity and implications for human pharmacology. Anesthesiology. 81: 1235-44. PMID 7978483 DOI: 10.1097/00000542-199411000-00018  0.446
1994 Schwinn DA. Adrenergic receptors: unique localization in human tissues. Advances in Pharmacology (San Diego, Calif.). 31: 333-41. PMID 7532987 DOI: 10.1016/S1054-3589(08)60626-2  0.4
1993 Liggett SB, Freedman NJ, Schwinn DA, Lefkowitz RJ. Structural basis for receptor subtype-specific regulation revealed by a chimeric beta 3/beta 2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 90: 3665-9. PMID 8386380 DOI: 10.1073/Pnas.90.8.3665  0.732
1993 Schwinn DA. Adrenoceptors as models for G protein-coupled receptors: structure, function and regulation. British Journal of Anaesthesia. 71: 77-85. PMID 8343342 DOI: 10.1093/Bja/71.1.77  0.332
1993 Price DT, Schwinn DA, Lomasney JW, Allen LF, Caron MG, Lefkowitz RJ. Identification, quantification, and localization of mRNA for three distinct alpha 1 adrenergic receptor subtypes in human prostate. The Journal of Urology. 150: 546-51. PMID 7686987 DOI: 10.1016/S0022-5347(17)35544-1  0.741
1993 Kwatra MM, Schwinn DA, Schreurs J, Blank JL, Kim CM, Benovic JL, Krause JE, Caron MG, Lefkowitz RJ. The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2. The Journal of Biological Chemistry. 268: 9161-4. PMID 7683643  0.312
1992 Thomas RF, Holt BD, Schwinn DA, Liggett SB. Long-term agonist exposure induces upregulation of beta 3-adrenergic receptor expression via multiple cAMP response elements. Proceedings of the National Academy of Sciences of the United States of America. 89: 4490-4. PMID 1374904 DOI: 10.1073/Pnas.89.10.4490  0.576
1992 Hoehe MR, Berrettini WH, Schwinn DA, Hsieh WT. A two-allele PstI RFLP for the alpha-1C adrenergic receptor gene (ADRA1C). Human Molecular Genetics. 1: 349. PMID 1363873 DOI: 10.1093/Hmg/1.5.349-A  0.435
1992 Schwinn DA, Lomasney JW. Pharmacologic characterization of cloned alpha 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype. European Journal of Pharmacology. 227: 433-6. PMID 1359975 DOI: 10.1016/0922-4106(92)90162-O  0.682
1992 Scheinin M, Schwinn DA. The locus coeruleus. Site of hypnotic actions of alpha 2-adrenoceptor agonists? Anesthesiology. 76: 873-5. PMID 1350888 DOI: 10.1097/00000542-199206000-00001  0.55
1991 Schwinn DA. Beta-adrenergic receptor function in surgical patients. Anesthesia and Analgesia. 72: 412. PMID 1847279 DOI: 10.1213/00000539-199103000-00029  0.389
1991 Lomasney JW, Cotecchia S, Lorenz W, Leung WY, Schwinn DA, Yang-Feng TL, Brownstein M, Lefkowitz RJ, Caron MG. Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. The Journal of Biological Chemistry. 266: 6365-9. PMID 1706716  0.764
1991 Liggett SB, Schwinn DA. Multiple potential regulatory elements in the 5' flanking region of the beta 3-adrenergic receptor. Dna Sequence : the Journal of Dna Sequencing and Mapping. 2: 61-3. PMID 1666313 DOI: 10.3109/10425179109008441  0.578
1991 Schwinn DA, Leone BJ, Spahn DR, Chesnut LC, Page SO, McRae RL, Liggett SB. Desensitization of myocardial beta-adrenergic receptors during cardiopulmonary bypass. Evidence for early uncoupling and late downregulation. Circulation. 84: 2559-67. PMID 1659956 DOI: 10.1161/01.Cir.84.6.2559  0.588
1991 Schwinn DA, Page SO, Middleton JP, Lorenz W, Liggett SB, Yamamoto K, Lapetina EG, Caron MG, Lefkowitz RJ, Cotecchia S. The alpha 1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogeneity. Molecular Pharmacology. 40: 619-26. PMID 1658600  0.3
1991 Schwinn DA, Leone BJ, Chesnut LC, Spahn DR, Page SO, Liggett SB. β-ADRENERGIC RECEPTOR DESENSITIZATION DURING CARDIOPULMONARY BYPASS Anesthesiology. 75: A1119. DOI: 10.1097/00000542-199109001-01118  0.568
1991 Schwinn D, Page S, Cotecchia S, Caron M, Lefkowitz R. THE α1-ADRENERGIC RECEPTOR SUBTYPE COUPLES TO PHOSPHOLIPASE C Anesthesiology. 75: A629-A629. DOI: 10.1097/00000542-199109001-00628  0.704
1990 Schwinn DA, Lomasney JW, Lorenz W, Szklut PJ, Fremeau RT, Yang-Feng TL, Caron MG, Lefkowitz RJ, Cotecchia S. Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype. The Journal of Biological Chemistry. 265: 8183-9. PMID 1970822  0.767
1990 Schwinn DA, Cotecchia S, Lorenz W, Caron MG, Lefkowitz RJ. The alpha 1C-adrenergic receptor: a new member in the alpha 1-adrenergic receptor family. Transactions of the Association of American Physicians. 103: 112-8. PMID 1966743  0.352
1990 Schwinn DA, Cotecchia S, Lomasney J, Caron M, Lefkowitz RJ. MOLECULAR CLONING AND EXPRESSION OF A NEW ALPHA-1-ADRENERGIC RECEPTOR SUBTYPE Anesthesia & Analgesia. 70: S359. DOI: 10.1213/00000539-199002001-00359  0.789
1988 Cotecchia S, Schwinn DA, Randall RR, Lefkowitz RJ, Caron MG, Kobilka BK. Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 7159-63. PMID 2845398 DOI: 10.1073/Pnas.85.19.7159  0.768
1988 Schwinn DA, McIntyre RW, Hawkins ED, Kates RA, Reves JG. alpha 1-Adrenergic responsiveness during coronary artery bypass surgery: effect of preoperative ejection fraction. Anesthesiology. 69: 206-17. PMID 2841891 DOI: 10.1097/00000542-198808000-00009  0.356
1988 Schwinn D, Mclntyre R, Reves J. EFFECT OF ISOFLURANE ANESTHESIA ON ALPHA-1-ADRENERGIC RESPONSIVENESS IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY Anesthesiology. 69: 137-137. DOI: 10.1097/00000542-198809010-00137  0.334
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