| Year |
Citation |
Score |
| 2024 |
Hu Q, Botuyan MV, Mer G. Identification of a conserved α-helical domain at the N terminus of human DNA methyltransferase 1. The Journal of Biological Chemistry. 300: 105775. PMID 38382673 DOI: 10.1016/j.jbc.2024.105775 |
0.381 |
|
| 2024 |
Hu Q, Zhao D, Cui G, Bhandari J, Thompson JR, Botuyan MV, Mer G. Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Molecular Cell. PMID 38242129 DOI: 10.1016/j.molcel.2023.12.036 |
0.409 |
|
| 2023 |
McCauley MJ, Joshi J, Becker N, Hu Q, Botuyan MV, Rouzina I, Mer G, James Maher L, Williams MC. Quantifying ATP-Independent Nucleosome Chaperone Activity with Single-Molecule Methods. Methods in Molecular Biology (Clifton, N.J.). 2694: 29-55. PMID 37823998 DOI: 10.1007/978-1-0716-3377-9_2 |
0.384 |
|
| 2023 |
Cui G, Botuyan MV, Drané P, Hu Q, Bragantini B, Thompson JR, Schuller DJ, Detappe A, Perfetti MT, James LI, Frye SV, Chowdhury D, Mer G. An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering. Nature Communications. 14: 6091. PMID 37773238 DOI: 10.1038/s41467-023-41821-6 |
0.318 |
|
| 2023 |
Cui G, Botuyan MV, Drané P, Hu Q, Bragantini B, Thompson JR, Schuller DJ, Perfetti MT, James LI, Frye SV, Chowdhury D, Mer G. An autoinhibited state of 53BP1 revealed by chemical probes and protein engineering. Biorxiv : the Preprint Server For Biology. PMID 37131705 DOI: 10.1101/2023.04.20.534960 |
0.324 |
|
| 2022 |
McCauley MJ, Morse M, Becker N, Hu Q, Botuyan MV, Navarrete E, Huo R, Muthurajan UM, Rouzina I, Luger K, Mer G, Maher LJ, Williams MC. Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes. Cell Reports. 41: 111858. PMID 36577379 DOI: 10.1016/j.celrep.2022.111858 |
0.424 |
|
| 2021 |
Ma J, Shi Q, Cui G, Sheng H, Botuyan MV, Zhou Y, Yan Y, He Y, Wang L, Wang Y, Mer G, Ye D, Wang C, Huang H. SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition. Nature Communications. 12: 5779. PMID 34599168 DOI: 10.1038/s41467-021-26049-6 |
0.333 |
|
| 2021 |
Hu Q, Botuyan MV, Zhao D, Cui G, Mer E, Mer G. Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. Nature. PMID 34321665 DOI: 10.1038/s41586-021-03716-8 |
0.441 |
|
| 2021 |
Du Truong C, Craig TA, Cui G, Botuyan MV, Serkasevich RA, Chan KY, Mer G, Chiu PL, Kumar R. Cryo-EM reveals conformational flexibility in apo DNA polymerase ζ. The Journal of Biological Chemistry. 100912. PMID 34174285 DOI: 10.1016/j.jbc.2021.100912 |
0.365 |
|
| 2021 |
Wang D, Ma J, Botuyan MV, Cui G, Yan Y, Ding D, Zhou Y, Krueger EW, Pei J, Wu X, Wang L, Pei H, McNiven MA, Ye D, Mer G, et al. ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication. Science Advances. 7. PMID 34144977 DOI: 10.1126/sciadv.abd9208 |
0.37 |
|
| 2021 |
Parnandi N, Rendo V, Cui G, Botuyan MV, Remisova M, Nguyen H, Drané P, Beroukhim R, Altmeyer M, Mer G, Chowdhury D. TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs. Molecular Cell. PMID 33961797 DOI: 10.1016/j.molcel.2021.03.039 |
0.309 |
|
| 2020 |
Walser F, Mulder MPC, Bragantini B, Burger S, Gubser T, Gatti M, Botuyan MV, Villa A, Altmeyer M, Neri D, Ovaa H, Mer G, Penengo L. Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response. Molecular Cell. PMID 33022275 DOI: 10.1016/j.molcel.2020.09.017 |
0.394 |
|
| 2020 |
McCauley MJ, Huo R, Navarrete E, Becker NA, Hu Q, Muthurajan U, Rouzina I, Luger K, Mer G, Maher LJ, Israeloff N, Williams MC. Pieces of the Puzzle: Individual hFACT Subdomains Coordinate to Remodel Nucleosomes Biophysical Journal. 118: 378a. DOI: 10.1016/J.Bpj.2019.11.2162 |
0.3 |
|
| 2019 |
McCauley MJ, Huo R, Navarrete E, Becker N, Hu Q, Nelson Holte M, Muthurajan U, Rouzina I, Luger K, Mer G, Maher LJ, Israeloff N, Williams MC. Destabilizing Nucleosomes and the Role of HMGB Proteins Biophysical Journal. 116: 72a. DOI: 10.1016/J.Bpj.2018.11.432 |
0.341 |
|
| 2018 |
Botuyan MV, Cui G, Drané P, Oliveira C, Detappe A, Brault ME, Parnandi N, Chaubey S, Thompson JR, Bragantini B, Zhao D, Chapman JR, Chowdhury D, Mer G. Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nature Structural & Molecular Biology. PMID 29967538 DOI: 10.1038/S41594-018-0083-Z |
0.48 |
|
| 2018 |
Cui G, Botuyan MV, Mer G. Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin. Journal of Molecular Biology. PMID 29778604 DOI: 10.1016/J.Jmb.2018.05.017 |
0.481 |
|
| 2017 |
Mer G, Botuyan MV. A New BRCT Binding Mode in TopBP1-BLM Helicase Interaction. Structure (London, England : 1993). 25: 1471-1472. PMID 28978405 DOI: 10.1016/J.Str.2017.09.011 |
0.392 |
|
| 2017 |
Hu Q, Botuyan MV, Cui G, Zhao D, Mer G. Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18. Molecular Cell. PMID 28506460 DOI: 10.1016/J.Molcel.2017.04.009 |
0.488 |
|
| 2017 |
Drané P, Brault ME, Cui G, Meghani K, Chaubey S, Detappe A, Parnandi N, He Y, Zheng XF, Botuyan MV, Kalousi A, Yewdell WT, Münch C, Harper JW, Chaudhuri J, ... ... Mer G, et al. TIRR regulates 53BP1 by masking its histone methyl-lysine binding function. Nature. PMID 28241136 DOI: 10.1038/Nature21358 |
0.546 |
|
| 2017 |
Valieva ME, Gerasimova NS, Kudryashova KS, Kozlova AL, Kirpichnikov MP, Hu Q, Botuyan MV, Mer G, Feofanov AV, Studitsky VM. Stabilization of Nucleosomes by Histone Tails and by FACT Revealed by spFRET Microscopy. Cancers. 9. PMID 28067802 DOI: 10.3390/Cancers9010003 |
0.524 |
|
| 2016 |
Klein BJ, Wang X, Cui G, Yuan C, Botuyan MV, Lin K, Lu Y, Wang X, Zhao Y, Bruns CJ, Mer G, Shi X, Kutateladze TG. PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation. Cell Reports. 17: 1158-1170. PMID 27760318 DOI: 10.1016/J.Celrep.2016.09.056 |
0.439 |
|
| 2016 |
Kanakkanthara A, Jeganathan KB, Limzerwala JF, Baker DJ, Hamada M, Nam HJ, van Deursen WH, Hamada N, Naylor RM, Becker NA, Davies BA, van Ree JH, Mer G, Shapiro VS, Maher LJ, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science (New York, N.Y.). 353: 1549-1552. PMID 27708105 DOI: 10.1126/Science.Aaf7463 |
0.368 |
|
| 2015 |
Baets J, Duan X, Wu Y, Smith G, Seeley WW, Mademan I, McGrath NM, Beadell NC, Khoury J, Botuyan MV, Mer G, Worrell GA, Hojo K, DeLeon J, Laura M, et al. Defects of mutant DNMT1 are linked to a spectrum of neurological disorders. Brain : a Journal of Neurology. 138: 845-61. PMID 25678562 DOI: 10.1093/Brain/Awv010 |
0.368 |
|
| 2015 |
Tong Q, Mazur SJ, Rincon-Arano H, Rothbart SB, Kuznetsov DM, Cui G, Liu WH, Gete Y, Klein BJ, Jenkins L, Mer G, Kutateladze AG, Strahl BD, Groudine M, Appella E, et al. An acetyl-methyl switch drives a conformational change in p53. Structure (London, England : 1993). 23: 322-31. PMID 25651062 DOI: 10.1016/J.Str.2014.12.010 |
0.419 |
|
| 2015 |
Perfetti MT, Baughman BM, Dickson BM, Mu Y, Cui G, Mader P, Dong A, Norris JL, Rothbart SB, Strahl BD, Brown PJ, Janzen WP, Arrowsmith CH, Mer G, McBride KM, et al. Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. Acs Chemical Biology. 10: 1072-81. PMID 25590533 DOI: 10.1021/Cb500956G |
0.513 |
|
| 2015 |
Tong Q, Cui G, Botuyan MV, Rothbart SB, Hayashi R, Musselman CA, Singh N, Appella E, Strahl BD, Mer G, Kutateladze TG. Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1. Structure (London, England : 1993). 23: 312-21. PMID 25579814 DOI: 10.1016/J.Str.2014.11.013 |
0.616 |
|
| 2015 |
James LI, Stuckey JI, Baughman BM, Perfetti MT, Pattenden SG, Dickson BM, Norris JL, Cui G, Mader P, Dong A, Mu Y, Rothbart SB, Strahl BD, Min J, Brown PJ, ... ... Mer G, et al. Abstract SY08-03: Targeting chromatin regulation for cancer therapy: progress towards chemical probes for methyl-lysine readers Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy08-03 |
0.469 |
|
| 2014 |
Cui G, Botuyan MV, Mer G. Solution structure of 53BP1 tandem Tudor domains in complex with a p53K370me2 peptide Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Mwo/Pdb |
0.364 |
|
| 2014 |
Cui G, Botuyan MV, Mer G. Solution structure of 53BP1 tandem Tudor domains in complex with a p53K382me2 peptide Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr25348 |
0.364 |
|
| 2013 |
Tang J, Cho NW, Cui G, Manion EM, Shanbhag NM, Botuyan MV, Mer G, Greenberg RA. Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nature Structural & Molecular Biology. 20: 317-25. PMID 23377543 DOI: 10.1038/Nsmb.2499 |
0.488 |
|
| 2013 |
Klein CJ, Bird T, Ertekin-Taner N, Lincoln S, Hjorth R, Wu Y, Kwok J, Mer G, Dyck PJ, Nicholson GA. DNMT1 mutation hot spot causes varied phenotypes of HSAN1 with dementia and hearing loss. Neurology. 80: 824-8. PMID 23365052 DOI: 10.1212/Wnl.0B013E318284076D |
0.366 |
|
| 2013 |
Cui G, Botuyan MV, Mer G. (1)H, (15)N and (13)C resonance assignments for the three LOTUS RNA binding domains of Tudor domain-containing protein TDRD7. Biomolecular Nmr Assignments. 7: 79-83. PMID 22481467 DOI: 10.1007/S12104-012-9382-1 |
0.415 |
|
| 2012 |
Ramachandran PL, Craig TA, Atanasova EA, Cui G, Owen BA, Bergen HR, Mer G, Kumar R. The potassium channel interacting protein 3 (DREAM/KChIP3) heterodimerizes with and regulates calmodulin function. The Journal of Biological Chemistry. 287: 39439-48. PMID 23019329 DOI: 10.1074/Jbc.M112.398495 |
0.333 |
|
| 2012 |
Singh N, Basnet H, Wiltshire TD, Mohammad DH, Thompson JR, Héroux A, Botuyan MV, Yaffe MB, Couch FJ, Rosenfeld MG, Mer G. Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1. Proceedings of the National Academy of Sciences of the United States of America. 109: 14381-6. PMID 22908299 DOI: 10.1073/Pnas.1212366109 |
0.62 |
|
| 2012 |
Cui G, Park S, Badeaux AI, Kim D, Lee J, Thompson JR, Yan F, Kaneko S, Yuan Z, Botuyan MV, Bedford MT, Cheng JQ, Mer G. PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. Nature Structural & Molecular Biology. 19: 916-24. PMID 22864287 DOI: 10.1038/Nsmb.2353 |
0.391 |
|
| 2012 |
Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, Mer G, Sixma TK, Richard S. RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. The Embo Journal. 31: 1865-78. PMID 22373579 DOI: 10.1038/Emboj.2012.47 |
0.481 |
|
| 2012 |
Fazly A, Li Q, Hu Q, Mer G, Horazdovsky B, Zhang Z. Histone chaperone Rtt106 promotes nucleosome formation using (H3-H4)2 tetramers. The Journal of Biological Chemistry. 287: 10753-60. PMID 22337870 DOI: 10.1074/Jbc.M112.347450 |
0.371 |
|
| 2012 |
Su D, Hu Q, Li Q, Thompson JR, Cui G, Fazly A, Davies BA, Botuyan MV, Zhang Z, Mer G. Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106. Nature. 483: 104-7. PMID 22307274 DOI: 10.1038/Nature10861 |
0.419 |
|
| 2012 |
Singh N, Wiltshire TD, Thompson JR, Mer G, Couch FJ. Molecular basis for the association of microcephalin (MCPH1) protein with the cell division cycle protein 27 (Cdc27) subunit of the anaphase-promoting complex. The Journal of Biological Chemistry. 287: 2854-62. PMID 22139841 DOI: 10.1074/Jbc.M111.307868 |
0.648 |
|
| 2012 |
Cui G, Botuyan MV, Mer G. Methylated Histone Complex Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr18579 |
0.33 |
|
| 2012 |
Hu Q, Cui G, Mer G. 1H, 15N and 13C resonance assignments for the N-terminal dimeric region of budding yeast histone chaperone Rtt106 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr17832 |
0.332 |
|
| 2012 |
Wiltshire TD, Singh N, Mer G, Couch F. Abstract 2133: MCPH1 interacts with the anaphase-promoting complex subunit Cdc27 Cancer Research. 72: 2133-2133. DOI: 10.1158/1538-7445.Am2012-2133 |
0.634 |
|
| 2011 |
Bian C, Xu C, Ruan J, Lee KK, Burke TL, Tempel W, Barsyte D, Li J, Wu M, Zhou BO, Fleharty BE, Paulson A, Allali-Hassani A, Zhou JQ, Mer G, et al. Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. The Embo Journal. 30: 2829-42. PMID 21685874 DOI: 10.1038/Emboj.2011.193 |
0.483 |
|
| 2011 |
Klein CJ, Botuyan MV, Wu Y, Ward CJ, Nicholson GA, Hammans S, Hojo K, Yamanishi H, Karpf AR, Wallace DC, Simon M, Lander C, Boardman LA, Cunningham JM, Smith GE, ... ... Mer G, et al. Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. Nature Genetics. 43: 595-600. PMID 21532572 DOI: 10.1038/Ng.830 |
0.409 |
|
| 2011 |
Su D, Hu Q, Zhou H, Thompson JR, Xu RM, Zhang Z, Mer G. Structure and histone binding properties of the Vps75-Rtt109 chaperone-lysine acetyltransferase complex. The Journal of Biological Chemistry. 286: 15625-9. PMID 21454705 DOI: 10.1074/Jbc.C111.220715 |
0.361 |
|
| 2010 |
Cui G, Benirschke RC, Tuan HF, Juranić N, Macura S, Botuyan MV, Mer G. Structural basis of ubiquitin recognition by translesion synthesis DNA polymerase ι. Biochemistry. 49: 10198-207. PMID 21049971 DOI: 10.1021/Bi101303T |
0.494 |
|
| 2010 |
Benirschke RC, Thompson JR, Nominé Y, Wasielewski E, Juranić N, Macura S, Hatakeyama S, Nakayama KI, Botuyan MV, Mer G. Molecular basis for the association of human E4B U box ubiquitin ligase with E2-conjugating enzymes UbcH5c and Ubc4. Structure (London, England : 1993). 18: 955-65. PMID 20696396 DOI: 10.1016/J.Str.2010.04.017 |
0.371 |
|
| 2010 |
Lukat-Rodgers GS, Correia C, Botuyan MV, Mer G, Rodgers KR. Heme-based sensing by the mammalian circadian protein CLOCK. Inorganic Chemistry. 49: 6349-65. PMID 20666392 DOI: 10.1021/Ic902388Q |
0.337 |
|
| 2010 |
Chadli A, Felts SJ, Wang Q, Sullivan WP, Botuyan MV, Fauq A, Ramirez-Alvarado M, Mer G. Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23. The Journal of Biological Chemistry. 285: 4224-31. PMID 19996313 DOI: 10.1074/Jbc.M109.081018 |
0.314 |
|
| 2009 |
Cui G, Botuyan MV, Mer G. Preparation of recombinant peptides with site- and degree-specific lysine (13)C-methylation. Biochemistry. 48: 3798-800. PMID 19334741 DOI: 10.1021/Bi900348Z |
0.387 |
|
| 2008 |
Xu C, Cui G, Botuyan MV, Mer G. Structural basis for the recognition of methylated histone H3K36 by the Eaf3 subunit of histone deacetylase complex Rpd3S. Structure (London, England : 1993). 16: 1740-50. PMID 18818090 DOI: 10.1016/J.Str.2008.08.008 |
0.464 |
|
| 2008 |
Nominé Y, Botuyan MV, Bajzer Z, Owen WG, Caride AJ, Wasielewski E, Mer G. Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations. Biochemistry. 47: 9866-79. PMID 18717574 DOI: 10.1021/Bi702247D |
0.456 |
|
| 2008 |
Xu C, Wu L, Cui G, Botuyan MV, Chen J, Mer G. Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites. Journal of Molecular Biology. 381: 361-72. PMID 18582474 DOI: 10.1016/J.Jmb.2008.05.087 |
0.509 |
|
| 2008 |
Lee J, Thompson JR, Botuyan MV, Mer G. Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nature Structural & Molecular Biology. 15: 109-11. PMID 18084306 DOI: 10.1038/Nsmb1326 |
0.421 |
|
| 2007 |
Wood JL, Singh N, Mer G, Chen J. MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage. The Journal of Biological Chemistry. 282: 35416-23. PMID 17925396 DOI: 10.1074/Jbc.M705245200 |
0.615 |
|
| 2006 |
Botuyan MV, Lee J, Ward IM, Kim JE, Thompson JR, Chen J, Mer G. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell. 127: 1361-73. PMID 17190600 DOI: 10.1016/J.Cell.2006.10.043 |
0.495 |
|
| 2006 |
Ward I, Kim JE, Minn K, Chini CC, Mer G, Chen J. The tandem BRCT domain of 53BP1 is not required for its repair function. The Journal of Biological Chemistry. 281: 38472-7. PMID 17043355 DOI: 10.1074/Jbc.M607577200 |
0.492 |
|
| 2004 |
Botuyan MV, Nominé Y, Yu X, Juranic N, Macura S, Chen J, Mer G. Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains. Structure (London, England : 1993). 12: 1137-46. PMID 15242590 DOI: 10.1016/J.Str.2004.06.002 |
0.513 |
|
| 2003 |
Yu X, Chini CC, He M, Mer G, Chen J. The BRCT domain is a phospho-protein binding domain. Science (New York, N.Y.). 302: 639-42. PMID 14576433 DOI: 10.1126/Science.1088753 |
0.491 |
|
| 2001 |
Botuyan MV, Mer G, Yi GS, Koth CM, Case DA, Edwards AM, Chazin WJ, Arrowsmith CH. Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide Journal of Molecular Biology. 312: 177-186. PMID 11545595 DOI: 10.1006/Jmbi.2001.4938 |
0.327 |
|
| 2000 |
Mer G, Bochkarev A, Gupta R, Bochkareva E, Frappier L, Ingles CJ, Edwards AM, Chazin WJ. Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA Cell. 103: 449-456. PMID 11081631 DOI: 10.1016/S0092-8674(00)00136-7 |
0.397 |
|
| 1999 |
Botuyan MV, Koth CM, Mer G, Chakrabartty A, Conaway JW, Conaway RC, Edwards AM, Arrowsmith CH, Chazin WJ. Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C Proceedings of the National Academy of Sciences of the United States of America. 96: 9033-9038. PMID 10430890 DOI: 10.1073/Pnas.96.16.9033 |
0.359 |
|
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