| Year |
Citation |
Score |
| 2022 |
Kallimanis P, Chinou I, Panagiotopoulou A, Soshilov AA, He G, Denison MS, Magiatis P. L. Leaf Extracts and Their Metabolites Inhibit the Aryl Hydrocarbon Receptor (AhR) Activation In Vitro and in Human Keratinocytes: Potential Impact on Inflammatory Skin Diseases and Skin Cancer. Molecules (Basel, Switzerland). 27. PMID 35458697 DOI: 10.3390/molecules27082499 |
0.752 |
|
| 2020 |
Kazzaz SA, Giani Tagliabue S, Franks DG, Denison MS, Hahn ME, Bonati L, Powell WH. An Aryl Hydrocarbon Receptor from the Caecilian Gymnopis multiplicata Suggests Low Dioxin Affinity in the Ancestor of All Three Amphibian Orders. General and Comparative Endocrinology. 113592. PMID 32858041 DOI: 10.1016/J.Ygcen.2020.113592 |
0.47 |
|
| 2020 |
Faber SC, Giani Tagliabue S, Bonati L, Denison MS. The Cellular and Molecular Determinants of Naphthoquinone-Dependent Activation of the Aryl Hydrocarbon Receptor. International Journal of Molecular Sciences. 21. PMID 32526934 DOI: 10.3390/Ijms21114111 |
0.561 |
|
| 2020 |
Hayashi A, Denison MS. Development of a novel recombinant cell line for detection and characterization of Ah receptor nuclear translocation in intact cells. Toxicology in Vitro : An International Journal Published in Association With Bibra. 66: 104873. PMID 32333947 DOI: 10.1016/J.Tiv.2020.104873 |
0.546 |
|
| 2020 |
Soshilov AA, Motta S, Bonati L, Denison MS. Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form. International Journal of Molecular Sciences. 21. PMID 32252465 DOI: 10.3390/Ijms21072474 |
0.763 |
|
| 2020 |
Chan LK, Nguyen KQ, Karim N, Yang Y, Rice RH, He G, Denison MS, Nguyen TB. Relationship between the molecular composition, visible light absorption, and health-related properties of smoldering woodsmoke aerosols Atmospheric Chemistry and Physics. 20: 539-559. DOI: 10.5194/Acp-20-539-2020 |
0.396 |
|
| 2019 |
Mexia N, Koutrakis S, He G, Skaltsounis AL, Denison MS, Magiatis P. A biomimetic, one-step transformation of simple indolic compounds to Malassezia-related alkaloids with high AhR potency and efficacy. Chemical Research in Toxicology. PMID 31647221 DOI: 10.1021/Acs.Chemrestox.9B00270 |
0.445 |
|
| 2019 |
Giani Tagliabue S, Faber SC, Motta S, Denison MS, Bonati L. Modeling the binding of diverse ligands within the Ah receptor ligand binding domain. Scientific Reports. 9: 10693. PMID 31337850 DOI: 10.1038/S41598-019-47138-Z |
0.506 |
|
| 2019 |
Hawerkamp HC, Kislat A, Gerber PA, Pollet M, Rolfes KM, Soshilov AA, Denison MS, Momin AA, Arold ST, Datsi A, Braun SA, Oláh P, Lacouture ME, Krutmann J, Haarmann-Stemmann T, et al. Vemurafenib acts as an aryl hydrocarbon receptor antagonist: Implications for inflammatory cutaneous adverse events. Allergy. PMID 31269229 DOI: 10.1111/All.13972 |
0.687 |
|
| 2019 |
Guo W, Van Langenhove K, Vandermarken T, Denison MS, Elskens M, Baeyens W, Gao Y. In situ measurement of estrogenic activity in various aquatic systems using organic diffusive gradients in thin-film coupled with ERE-CALUX bioassay. Environment International. 127: 13-20. PMID 30897513 DOI: 10.1016/J.Envint.2019.03.027 |
0.324 |
|
| 2018 |
Corre S, Tardif N, Mouchet N, Leclair HM, Boussemart L, Gautron A, Bachelot L, Perrot A, Soshilov A, Rogiers A, Rambow F, Dumontet E, Tarte K, Bessede A, Guillemin GJ, ... ... Denison MS, et al. Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma. Nature Communications. 9: 4775. PMID 30429474 DOI: 10.1038/S41467-018-06951-2 |
0.722 |
|
| 2018 |
Faber SC, Soshilov AA, Giani Tagliabue S, Bonati L, Denison MS. Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist. International Journal of Molecular Sciences. 19. PMID 30201897 DOI: 10.3390/Ijms19092692 |
0.795 |
|
| 2018 |
Dou L, Poitevin S, Sallée M, Addi T, Gondouin B, McKay N, Denison MS, Jourde-Chiche N, Duval-Sabatier A, Cerini C, Brunet P, Dignat-George F, Burtey S. Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease. Kidney International. PMID 29395338 DOI: 10.1016/J.Kint.2017.11.010 |
0.325 |
|
| 2018 |
Hawerkamp H, Kislat A, Gerber P, Pollet M, Soshilov A, Denison M, Momin A, Arold S, Datsi A, Braun S, Lacouture M, Haarmann-Stemmann T, Homey B, Meller S. 1057 Vemurafenib acts as an aryl hydrocarbon receptor antagonist Journal of Investigative Dermatology. 138: S179. DOI: 10.1016/J.Jid.2018.03.1070 |
0.723 |
|
| 2017 |
Guo W, Van Langenhove K, Denison MS, Baeyens WF, Elskens M, Gao Y. A Novel Tool for Estrogenic Activity Measurements in Water Using Diffusion Gradients in Thin-film Coupled with an Estrogen Bioassay. Analytical Chemistry. PMID 29151339 DOI: 10.1021/Acs.Analchem.7B03537 |
0.318 |
|
| 2017 |
Denison MS, Faber SC. And Now for Something Completely Different: Diversity in Ligand-Dependent Activation of Ah Receptor Responses. Current Opinion in Toxicology. 2: 124-131. PMID 28845473 DOI: 10.1016/J.Cotox.2017.01.006 |
0.395 |
|
| 2017 |
Denison MS, Faber SC. And Now for Something Completely Different: Diversity in Ligand-Dependent Activation of Ah Receptor Responses. Current Opinion in Toxicology. 2: 124-131. PMID 28845473 DOI: 10.1016/J.Cotox.2017.01.006 |
0.395 |
|
| 2017 |
Lam MM, Engwall M, Denison MS, Larsson M. METHYLATED PAHS AND/OR THEIR METABOLITES ARE IMPORTANT CONTRIBUTORS TO THE OVERALL ESTROGENIC ACTIVITY OF PAH-CONTAMINATED SOILS. Environmental Toxicology and Chemistry. PMID 28834568 DOI: 10.1002/Etc.3958 |
0.398 |
|
| 2017 |
Neale PA, Altenburger R, Aït-Aïssa S, Brion F, Busch W, de Aragão Umbuzeiro G, Denison MS, Du Pasquier D, Hilscherová K, Hollert H, Morales DA, Novák J, Schlichting R, Seiler TB, Serra H, et al. Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water. Water Research. 123: 734-750. PMID 28728110 DOI: 10.1016/J.Watres.2017.07.016 |
0.317 |
|
| 2017 |
Anderson CG, Joshi G, Bair DA, Oriol C, He G, Parikh SJ, Denison MS, Scow KM. Use of nuclear receptor luciferase-based bioassays to detect endocrine active chemicals in a biosolids-biochar amended soil. Chemosphere. 181: 160-167. PMID 28437741 DOI: 10.1016/J.Chemosphere.2017.04.035 |
0.369 |
|
| 2017 |
Corrada D, Denison MS, Bonati L. Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization. Molecular Biosystems. PMID 28393157 DOI: 10.1039/C7Mb00005G |
0.384 |
|
| 2017 |
Elshenawy OH, Abdelhamid G, Soshilov AA, Denison MS, El-Kadi AO. DOWN-REGULATION OF CYTOCHROME P450 1A1 BY MONOMETHYLARSONOUS ACID IN HUMAN HEPG2 CELLS. Toxicology Letters. PMID 28189647 DOI: 10.1016/J.Toxlet.2017.02.012 |
0.75 |
|
| 2017 |
Denison MS, van den Berg M. Editorial overview: The aryl hydrocarbon (Ah) receptor: From toxicology to human health Current Opinion in Toxicology. 2: i-iv. DOI: 10.1016/J.Cotox.2017.03.001 |
0.32 |
|
| 2016 |
Cheng Y, Jin UH, Davidson LA, Chapkin RS, Jayaraman A, Tamamis P, Orr A, Allred C, Denison MS, Soshilov A, Weaver E, Safe S. Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27837168 DOI: 10.1093/Toxsci/Kfw230 |
0.767 |
|
| 2016 |
Joshi G, Schmidt R, Scow KM, Denison MS, Hristova KR. Effect of benzene and ethylbenzene on the transcription of methyl-tert-butyl ether degradation genes of Methylibium petroleiphilum PM1. Microbiology (Reading, England). PMID 27450417 DOI: 10.1099/Mic.0.000338 |
0.352 |
|
| 2016 |
Corrada D, Soshilov AA, Denison MS, Bonati L. Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation. Plos Computational Biology. 12: e1004981. PMID 27295348 DOI: 10.1371/Journal.Pcbi.1004981 |
0.747 |
|
| 2016 |
Croes K, Van den Heuvel R, Van den Bril B, Staelens J, Denison MS, Van Langenhove K, Vandermarken T, Elskens M. Assessment of estrogenic and androgenic activity in PM10 air samples from an urban, industrial and rural area in Flanders (Belgium) using the CALUX bioassay. Environmental Research. 150: 66-72. PMID 27257826 DOI: 10.1016/J.Envres.2016.05.044 |
0.303 |
|
| 2016 |
Bak SM, Iida M, Soshilov AA, Denison MS, Iwata H, Kim EY. Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major). Archives of Toxicology. PMID 27188387 DOI: 10.1007/S00204-016-1732-9 |
0.77 |
|
| 2016 |
Cole BJ, Brander SM, Jeffries KM, Hasenbein S, He G, Denison MS, Fangue NA, Connon RE. Changes in Menidia beryllina Gene Expression and In Vitro Hormone-Receptor Activation After Exposure to Estuarine Waters Near Treated Wastewater Outfalls. Archives of Environmental Contamination and Toxicology. PMID 27155869 DOI: 10.1007/S00244-016-0282-8 |
0.355 |
|
| 2016 |
Croes K, Debaillie P, Van den Bril B, Staelens J, Vandermarken T, Van Langenhove K, Denison MS, Leermakers M, Elskens M. Assessment of estrogenic activity in PM10 air samples with the ERE-CALUX bioassay: Method optimization and implementation at an urban location in Flanders (Belgium). Chemosphere. 144: 392-8. PMID 26383266 DOI: 10.1016/J.Chemosphere.2015.09.020 |
0.338 |
|
| 2015 |
Khedidji S, Croes K, Yassaa N, Ladji R, Denison MS, Baeyens W, Elskens M. Assessment of dioxin-like activity in PM10 air samples from an industrial location in Algeria, using the DRE-CALUX bioassay. Environmental Science and Pollution Research International. PMID 26611627 DOI: 10.1007/S11356-015-5841-4 |
0.335 |
|
| 2015 |
Neale PA, Ait-Aissa S, Brack W, Creusot N, Denison MS, Deutschmann B, Hilscherova K, Hollert H, Krauss M, Novák J, Schulze T, Seiler TB, Serra H, Shao Y, Escher BI. Linking in vitro effects and detected organic micropollutants in surface water using mixture toxicity modeling. Environmental Science & Technology. PMID 26516785 DOI: 10.1021/Acs.Est.5B04083 |
0.403 |
|
| 2015 |
Caron-Beaudoin É, Denison MS, Sanderson JT. Effects of neonicotinoids on promoter-specific expression and activity of aromatase (CYP19) in human adrenocortical carcinoma (H295R) and primary umbilical vein endothelial (HUVEC) cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26464060 DOI: 10.1093/Toxsci/Kfv220 |
0.407 |
|
| 2015 |
Brennan JC, He G, Tsutsumi T, Zhao J, Wirth E, Fulton MH, Denison MS. Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Enhanced Responsiveness and Improved Detection Limits. Environmental Science & Technology. 49: 11903-12. PMID 26366531 DOI: 10.1021/Acs.Est.5B02906 |
0.409 |
|
| 2015 |
Brennan JC, Bassal A, He G, Denison MS. Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor α and β for improved detection of estrogenic/antiestrogenic chemicals. Environmental Toxicology and Chemistry / Setac. PMID 26139245 DOI: 10.1002/Etc.3146 |
0.435 |
|
| 2015 |
DeGroot DE, Franks DG, Higa T, Tanaka J, Hahn ME, Denison MS. Naturally Occurring Marine Brominated Indoles Are Aryl Hydrocarbon Receptor Ligands/Agonists. Chemical Research in Toxicology. 28: 1176-85. PMID 26001051 DOI: 10.1021/Acs.Chemrestox.5B00003 |
0.854 |
|
| 2015 |
Shoots J, Fraccalvieri D, Franks DG, Denison MS, Hahn ME, Bonati L, Powell WH. An Aryl Hydrocarbon Receptor from the Salamander Ambystoma mexicanum Exhibits Low Sensitivity to 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Environmental Science & Technology. 49: 6993-7001. PMID 25941739 DOI: 10.1021/Acs.Est.5B01299 |
0.447 |
|
| 2015 |
Joshi G, Schmidt R, Scow KM, Denison MS, Hristova KR. Gene mdpC plays a regulatory role in the methyl-tert-butyl ether degradation pathway of Methylibium petroleiphilum strain PM1. Fems Microbiology Letters. 362. PMID 25724531 DOI: 10.1093/Femsle/Fnv029 |
0.332 |
|
| 2015 |
Mexia N, Gaitanis G, Velegraki A, Soshilov A, Denison MS, Magiatis P. Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast. Archives of Biochemistry and Biophysics. 571: 16-20. PMID 25721496 DOI: 10.1016/J.Abb.2015.02.023 |
0.768 |
|
| 2015 |
Maayah ZH, Ghebeh H, Alhaider AA, El-Kadi AO, Soshilov AA, Denison MS, Ansari MA, Korashy HM. Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway. Toxicology and Applied Pharmacology. 284: 217-26. PMID 25697376 DOI: 10.1016/J.Taap.2015.02.007 |
0.73 |
|
| 2015 |
Bittner GD, Denison MS, Yang CZ, Stoner MA, He G. Chemicals having estrogenic activity can be released from some bisphenol A-free, hard and clear, thermoplastic resins. Environmental Health : a Global Access Science Source. 14: 103. PMID 25477047 DOI: 10.1186/1476-069X-13-103 |
0.358 |
|
| 2015 |
Frauenstein K, Tigges J, Soshilov AA, Kado S, Raab N, Fritsche E, Haendeler J, Denison MS, Vogel CF, Haarmann-Stemmann T. Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2). Archives of Toxicology. 89: 1329-36. PMID 25082669 DOI: 10.1007/S00204-014-1321-8 |
0.769 |
|
| 2014 |
Novotna A, Korhonova M, Bartonkova I, Soshilov AA, Denison MS, Bogdanova K, Kolar M, Bednar P, Dvorak Z. Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor. Plos One. 9: e101832. PMID 25000292 DOI: 10.1371/Journal.Pone.0101832 |
0.796 |
|
| 2014 |
Bessede A, Gargaro M, Pallotta MT, Matino D, Servillo G, Brunacci C, Bicciato S, Mazza EM, Macchiarulo A, Vacca C, Iannitti R, Tissi L, Volpi C, Belladonna ML, Orabona C, ... ... Denison MS, et al. Aryl hydrocarbon receptor control of a disease tolerance defence pathway. Nature. 511: 184-90. PMID 24930766 DOI: 10.1038/Nature13323 |
0.365 |
|
| 2014 |
Ghorbanzadeh M, van Ede KI, Larsson M, van Duursen MB, Poellinger L, Lücke-Johansson S, Machala M, P?n?íková K, Vondrá?ek J, van den Berg M, Denison MS, Ringsted T, Andersson PL. In vitro and in silico derived relative effect potencies of ah-receptor-mediated effects by PCDD/Fs and PCBs in rat, mouse, and guinea pig CALUX cell lines. Chemical Research in Toxicology. 27: 1120-32. PMID 24901989 DOI: 10.1021/Tx5001255 |
0.424 |
|
| 2014 |
Soshilov AA, Denison MS. Ligand promiscuity of aryl hydrocarbon receptor agonists and antagonists revealed by site-directed mutagenesis. Molecular and Cellular Biology. 34: 1707-19. PMID 24591650 DOI: 10.1128/Mcb.01183-13 |
0.778 |
|
| 2014 |
Vogel CF, Khan EM, Leung PS, Gershwin ME, Chang WL, Wu D, Haarmann-Stemmann T, Hoffmann A, Denison MS. Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-κB. The Journal of Biological Chemistry. 289: 1866-75. PMID 24302727 DOI: 10.1074/Jbc.M113.505578 |
0.695 |
|
| 2014 |
DeGroot DE, Hayashi A, Denison MS. Lack of ligand-selective binding of the aryl hydrocarbon receptor to putative DNA binding sites regulating expression of Bax and paraoxonase 1 genes. Archives of Biochemistry and Biophysics. 541: 13-20. PMID 24200861 DOI: 10.1016/J.Abb.2013.10.021 |
0.838 |
|
| 2014 |
Anwar-Mohamed A, Elshenawy OH, Soshilov AA, Denison MS, Chris Le X, Klotz LO, El-Kadi AO. Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms. Free Radical Biology & Medicine. 67: 171-87. PMID 24161444 DOI: 10.1016/J.Freeradbiomed.2013.10.810 |
0.749 |
|
| 2014 |
DeGroot DE, Denison MS. Nucleotide specificity of DNA binding of the aryl hydrocarbon receptor:ARNT complex is unaffected by ligand structure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 137: 102-13. PMID 24136190 DOI: 10.1093/Toxsci/Kft234 |
0.827 |
|
| 2014 |
He G, Zhao J, Brennan JC, Affatato AA, Zhao B, Rice RH, Denison MS. Cell-based assays for identification of aryl hydrocarbon receptor (AhR) activators Methods in Pharmacology and Toxicology. 221-235. DOI: 10.1007/978-1-62703-742-6-13 |
0.339 |
|
| 2014 |
Soshilov AA, Denison MS. DNA binding (gel retardation assay) analysis for identification of aryl hydrocarbon (Ah) receptor agonists and antagonists Methods in Pharmacology and Toxicology. 207-219. DOI: 10.1007/978-1-62703-742-6-12 |
0.77 |
|
| 2013 |
Brander SM, Connon RE, He G, Hobbs JA, Smalling KL, Teh SJ, White JW, Werner I, Denison MS, Cherr GN. From 'omics to otoliths: responses of an estuarine fish to endocrine disrupting compounds across biological scales. Plos One. 8: e74251. PMID 24086325 DOI: 10.1371/Journal.Pone.0074251 |
0.363 |
|
| 2013 |
Hu Q, He G, Zhao J, Soshilov A, Denison MS, Zhang A, Yin H, Fraccalvieri D, Bonati L, Xie Q, Zhao B. Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands. Plos One. 8: e66258. PMID 23776647 DOI: 10.1371/Journal.Pone.0066258 |
0.804 |
|
| 2013 |
Brennan JC, Denison MS, Holstege DM, Magiatis P, Dallas JL, Gutierrez EG, Soshilov AA, Millam JR. 2,3-cis-2R,3R-(-)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines. Bmc Complementary and Alternative Medicine. 13: 133. PMID 23768005 DOI: 10.1186/1472-6882-13-133 |
0.735 |
|
| 2013 |
Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Zapletalova M, Anzenbacher P, Dvorak Z. Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. Toxicology Letters. 221: 1-8. PMID 23735880 DOI: 10.1016/J.Toxlet.2013.05.007 |
0.765 |
|
| 2013 |
Croes K, Colles A, Koppen G, De Galan S, Vandermarken T, Govarts E, Bruckers L, Nelen V, Schoeters G, Van Larebeke N, Denison MS, Mampaey M, Baeyens W. Determination of PCDD/Fs, PBDD/Fs and dioxin-like PCBs in human milk from mothers residing in the rural areas in Flanders, using the CALUX bioassay and GC-HRMS Talanta. 113: 99-105. PMID 23708629 DOI: 10.1016/J.Talanta.2013.03.086 |
0.308 |
|
| 2013 |
van den Berg M, Denison MS, Birnbaum LS, Devito MJ, Fiedler H, Falandysz J, Rose M, Schrenk D, Safe S, Tohyama C, Tritscher A, Tysklind M, Peterson RE. Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds. Toxicological Sciences : An Official Journal of the Society of Toxicology. 133: 197-208. PMID 23492812 DOI: 10.1093/Toxsci/Kft070 |
0.322 |
|
| 2013 |
Magiatis P, Pappas P, Gaitanis G, Mexia N, Melliou E, Galanou M, Vlachos C, Stathopoulou K, Skaltsounis AL, Marselos M, Velegraki A, Denison MS, Bassukas ID. Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin. The Journal of Investigative Dermatology. 133: 2023-30. PMID 23448877 DOI: 10.1038/Jid.2013.92 |
0.386 |
|
| 2013 |
Zhao B, Bohonowych JE, Timme-Laragy A, Jung D, Affatato AA, Rice RH, Di Giulio RT, Denison MS. Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor. Plos One. 8: e56860. PMID 23441220 DOI: 10.1371/Journal.Pone.0056860 |
0.811 |
|
| 2013 |
Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Anzenbacher P, Dvorak Z. Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. Toxicology Letters. 218: 253-9. PMID 23419638 DOI: 10.1016/J.Toxlet.2013.01.020 |
0.776 |
|
| 2013 |
Odio C, Holzman SA, Denison MS, Fraccalvieri D, Bonati L, Franks DG, Hahn ME, Powell WH. Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis. Biochemistry. 52: 1746-54. PMID 23394719 DOI: 10.1021/Bi301722K |
0.453 |
|
| 2013 |
Fraccalvieri D, Soshilov AA, Karchner SI, Franks DG, Pandini A, Bonati L, Hahn ME, Denison MS. Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor. Biochemistry. 52: 714-25. PMID 23286227 DOI: 10.1021/Bi301457F |
0.781 |
|
| 2012 |
Brander SM, He G, Smalling KL, Denison MS, Cherr GN. The in vivo estrogenic and in vitro anti-estrogenic activity of permethrin and bifenthrin. Environmental Toxicology and Chemistry / Setac. 31: 2848-55. PMID 23007834 DOI: 10.1002/Etc.2019 |
0.415 |
|
| 2012 |
Wall RJ, He G, Denison MS, Congiu C, Onnis V, Fernandes A, Bell DR, Rose M, Rowlands JC, Balboni G, Mellor IR. Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context. Toxicology. 297: 26-33. PMID 22507882 DOI: 10.1016/J.Tox.2012.03.011 |
0.499 |
|
| 2012 |
Tiong CT, Chen C, Zhang SJ, Li J, Soshilov A, Denison MS, Lee LS, Tam VH, Wong SP, Xu HE, Yong EL. A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein. Carcinogenesis. 33: 1089-97. PMID 22345291 DOI: 10.1093/Carcin/Bgs110 |
0.729 |
|
| 2012 |
El Gendy MA, Soshilov AA, Denison MS, El-Kadi AO. Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 353-62. PMID 22037238 DOI: 10.1016/J.Fct.2011.10.052 |
0.774 |
|
| 2012 |
El Gendy MA, Soshilov AA, Denison MS, El-Kadi AO. Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol. Toxicology Letters. 208: 51-61. PMID 22001777 DOI: 10.1016/J.Toxlet.2011.09.030 |
0.774 |
|
| 2012 |
Wang Y, Yang D, Chang A, Chan WK, Zhao B, Denison MS, Xue L. Synthesis of a ligand-quencher conjugate for the ligand binding study of the aryl hydrocarbon receptor using a FRET assay Medicinal Chemistry Research. 21: 711-721. DOI: 10.1007/S00044-011-9575-7 |
0.489 |
|
| 2011 |
Motto I, Bordogna A, Soshilov AA, Denison MS, Bonati L. New aryl hydrocarbon receptor homology model targeted to improve docking reliability. Journal of Chemical Information and Modeling. 51: 2868-81. PMID 21981577 DOI: 10.1021/Ci2001617 |
0.776 |
|
| 2011 |
Denison MS, Soshilov AA, He G, DeGroot DE, Zhao B. Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 1-22. PMID 21908767 DOI: 10.1093/Toxsci/Kfr218 |
0.825 |
|
| 2011 |
Van Langenhove K, Croes K, Denison MS, Elskens M, Baeyens W. The CALUX bio-assay: analytical comparison between mouse hepatoma cell lines with a low (H1L6.1c3) and high (H1L7.5c1) number of dioxin response elements. Talanta. 85: 2039-46. PMID 21872055 DOI: 10.1016/J.Talanta.2011.07.042 |
0.346 |
|
| 2011 |
Elskens M, Baston DS, Stumpf C, Haedrich J, Keupers I, Croes K, Denison MS, Baeyens W, Goeyens L. CALUX measurements: statistical inferences for the dose-response curve. Talanta. 85: 1966-73. PMID 21872045 DOI: 10.1016/J.Talanta.2011.07.014 |
0.784 |
|
| 2011 |
Soshilov A, Denison MS. Ligand displaces heat shock protein 90 from overlapping binding sites within the aryl hydrocarbon receptor ligand-binding domain. The Journal of Biological Chemistry. 286: 35275-82. PMID 21856752 DOI: 10.1074/Jbc.M111.246439 |
0.766 |
|
| 2011 |
He G, Tsutsumi T, Zhao B, Baston DS, Zhao J, Heath-Pagliuso S, Denison MS. Third-generation Ah receptor-responsive luciferase reporter plasmids: amplification of dioxin-responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness. Toxicological Sciences : An Official Journal of the Society of Toxicology. 123: 511-22. PMID 21775728 DOI: 10.1093/Toxsci/Kfr189 |
0.82 |
|
| 2011 |
Korashy HM, Anwar-Mohamed A, Soshilov AA, Denison MS, El-Kadi AO. The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation. Chemical Research in Toxicology. 24: 1540-8. PMID 21732638 DOI: 10.1021/Tx200141P |
0.78 |
|
| 2011 |
Aung HH, Lame MW, Gohil K, He G, Denison MS, Rutledge JC, Wilson DW. Comparative gene responses to collected ambient particles in vitro: endothelial responses. Physiological Genomics. 43: 917-29. PMID 21652769 DOI: 10.1152/Physiolgenomics.00051.2011 |
0.393 |
|
| 2011 |
He G, Zhao B, Denison MS. Identification of benzothiazole derivatives and polycyclic aromatic hydrocarbons as aryl hydrocarbon receptor agonists present in tire extracts. Environmental Toxicology and Chemistry / Setac. 30: 1915-25. PMID 21590714 DOI: 10.1002/Etc.581 |
0.547 |
|
| 2011 |
Baston DS, Denison MS. Considerations for potency equivalent calculations in the Ah receptor-based CALUX bioassay: normalization of superinduction results for improved sample potency estimation. Talanta. 83: 1415-21. PMID 21238730 DOI: 10.1016/J.Talanta.2010.11.035 |
0.804 |
|
| 2011 |
Lee YC, Oslund KL, Thai P, Velichko S, Fujisawa T, Duong T, Denison MS, Wu R. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcription. American Journal of Respiratory Cell and Molecular Biology. 45: 270-6. PMID 20971882 DOI: 10.1165/Rcmb.2010-0313Oc |
0.426 |
|
| 2011 |
Degroot D, He G, Fraccalvieri D, Bonati L, Pandini A, Denison MS. AHR Ligands: Promiscuity in Binding and Diversity in Response The Ah Receptor in Biology and Toxicology. 63-79. DOI: 10.1002/9781118140574.ch4 |
0.324 |
|
| 2010 |
Kennedy K, Macova M, Bartkow ME, Hawker DW, Zhao B, Denison MS, Mueller JF. Effect based monitoring of seasonal ambient air exposures in Australia sampled by PUF passive air samplers. Atmospheric Pollution Research. 1: 50-58. PMID 21552507 DOI: 10.5094/Apr.2010.008 |
0.422 |
|
| 2010 |
Zhao B, Baston DS, Khan E, Sorrentino C, Denison MS. Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds. Science China. Chemistry. 53: 1010-1016. PMID 21394221 DOI: 10.1007/S11426-010-0142-8 |
0.803 |
|
| 2010 |
Boitano AE, Wang J, Romeo R, Bouchez LC, Parker AE, Sutton SE, Walker JR, Flaveny CA, Perdew GH, Denison MS, Schultz PG, Cooke MP. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science (New York, N.Y.). 329: 1345-8. PMID 20688981 DOI: 10.1126/Science.1191536 |
0.338 |
|
| 2010 |
Zhao B, Degroot DE, Hayashi A, He G, Denison MS. CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 393-403. PMID 20634293 DOI: 10.1093/Toxsci/Kfq217 |
0.838 |
|
| 2010 |
Petkov PI, Rowlands JC, Budinsky R, Zhao B, Denison MS, Mekenyan O. Mechanism-based common reactivity pattern (COREPA) modelling of aryl hydrocarbon receptor binding affinity Sar and Qsar in Environmental Research. 21: 187-214. PMID 20373220 DOI: 10.1080/10629360903570933 |
0.417 |
|
| 2009 |
Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environmental Health Perspectives. 117: 1867-72. PMID 20049205 DOI: 10.1289/Ehp.0900834 |
0.359 |
|
| 2009 |
Pandini A, Soshilov AA, Song Y, Zhao J, Bonati L, Denison MS. Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis. Biochemistry. 48: 5972-83. PMID 19456125 DOI: 10.1021/Bi900259Z |
0.778 |
|
| 2009 |
Kanematsu M, Hayashi A, Denison MS, Young TM. Characterization and potential environmental risks of leachate from shredded rubber mulches. Chemosphere. 76: 952-8. PMID 19450864 DOI: 10.1016/J.Chemosphere.2009.04.026 |
0.331 |
|
| 2009 |
Kennedy K, Macova M, Leusch F, Bartkow ME, Hawker DW, Zhao B, Denison MS, Mueller JF. Assessing indoor air exposures using passive sampling with bioanalytical methods for estrogenicity and aryl hydrocarbon receptor activity. Analytical and Bioanalytical Chemistry. 394: 1413-21. PMID 19430962 DOI: 10.1007/S00216-009-2825-6 |
0.382 |
|
| 2009 |
Jaikanlaya C, Settachan D, Denison MS, Ruchirawat M, van den Berg M. PCBs contamination in seafood species at the Eastern Coast of Thailand. Chemosphere. 76: 239-49. PMID 19375780 DOI: 10.1016/J.Chemosphere.2009.03.018 |
0.33 |
|
| 2009 |
Palumbo AJ, Denison MS, Doroshov SI, Tjeerdema RS. Reduction of vitellogenin synthesis by an aryl hydrocarbon receptor agonist in the white sturgeon (Acipenser transmontamus). Environmental Toxicology and Chemistry / Setac. 28: 1749-55. PMID 19292566 DOI: 10.1897/08-481.1 |
0.423 |
|
| 2009 |
La Merrill M, Baston DS, Denison MS, Birnbaum LS, Pomp D, Threadgill DW. Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat. American Journal of Physiology. Endocrinology and Metabolism. 296: E203-10. PMID 18840765 DOI: 10.1152/Ajpendo.90368.2008 |
0.76 |
|
| 2008 |
Soshilov A, Denison MS. Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptor. The Journal of Biological Chemistry. 283: 32995-3005. PMID 18806268 DOI: 10.1074/Jbc.M802414200 |
0.748 |
|
| 2008 |
Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kültz D, Chang DP, Gee SJ, Hammock BD. In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environmental Health Perspectives. 116: 1203-10. PMID 18795164 DOI: 10.1289/Ehp.11200 |
0.485 |
|
| 2008 |
Lawrence BP, Denison MS, Novak H, Vorderstrasse BA, Harrer N, Neruda W, Reichel C, Woisetschläger M. Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound. Blood. 112: 1158-65. PMID 18270326 DOI: 10.1182/Blood-2007-08-109645 |
0.416 |
|
| 2008 |
Bohonowych JE, Zhao B, Timme-Laragy A, Jung D, Di Giulio RT, Denison MS. Newspapers and newspaper ink contain agonists for the ah receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 102: 278-90. PMID 18203687 DOI: 10.1093/Toxsci/Kfn011 |
0.803 |
|
| 2007 |
Brown DJ, Orelien J, Gordon JD, Chu AC, Chu MD, Nakamura M, Handa H, Kayama F, Denison MS, Clark GC. Mathematical model developed for environmental samples: prediction of GC/MS dioxin TEQ from XDS-CALUX bioassay data. Environmental Science & Technology. 41: 4354-60. PMID 17626436 DOI: 10.1021/Es062602+ |
0.304 |
|
| 2007 |
Nording M, Denison MS, Baston D, Persson Y, Spinnel E, Haglund P. Analysis of dioxins in contaminated soils with the calux and caflux bioassays, an immunoassay, and gas chromatography/high-resolution mass spectrometry. Environmental Toxicology and Chemistry / Setac. 26: 1122-9. PMID 17571676 DOI: 10.1897/06-458R.1 |
0.781 |
|
| 2007 |
Bohonowych JE, Denison MS. Persistent binding of ligands to the aryl hydrocarbon receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 98: 99-109. PMID 17431010 DOI: 10.1093/Toxsci/Kfm085 |
0.8 |
|
| 2007 |
Hu W, Sorrentino C, Denison MS, Kolaja K, Fielden MR. Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro. Molecular Pharmacology. 71: 1475-86. PMID 17327465 DOI: 10.1124/Mol.106.032748 |
0.5 |
|
| 2007 |
Pandini A, Denison MS, Song Y, Soshilov AA, Bonati L. Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis. Biochemistry. 46: 696-708. PMID 17223691 DOI: 10.1021/Bi061460T |
0.772 |
|
| 2006 |
Van den Berg M, Birnbaum LS, Denison M, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws L, Rose M, Safe S, Schrenk D, Tohyama C, Tritscher A, et al. The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 223-41. PMID 16829543 DOI: 10.1093/Toxsci/Kfl055 |
0.36 |
|
| 2006 |
Zhao B, Baston DS, Hammock B, Denison MS. Interaction of diuron and related substituted phenylureas with the Ah receptor pathway. Journal of Biochemical and Molecular Toxicology. 20: 103-13. PMID 16788953 DOI: 10.1002/Jbt.20126 |
0.854 |
|
| 2006 |
Peters AK, Leonards PE, Zhao B, Bergman A, Denison MS, Van den Berg M. Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal Toxicology Letters. 165: 230-241. PMID 16750337 DOI: 10.1016/J.Toxlet.2006.04.005 |
0.367 |
|
| 2006 |
Klein GP, Hodge EM, Diamond ML, Yip A, Dann T, Stern G, Denison MS, Harper PA. Gas-phase ambient air contaminants exhibit significant dioxin-like and estrogen-like activity in vitro. Environmental Health Perspectives. 114: 697-703. PMID 16675423 DOI: 10.1289/Ehp.8496 |
0.329 |
|
| 2006 |
Peters AK, Nijmeijer S, Gradin K, Backlund M, Bergman A, Poellinger L, Denison MS, Van den Berg M. Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway Toxicological Sciences. 92: 133-142. PMID 16601081 DOI: 10.1093/Toxsci/Kfj186 |
0.565 |
|
| 2006 |
Jeong M, Kim H, You A, Park K, Kim B, Kim J, Denison MS. Determination of Androgenic activity on a stably transfected human breast cell line Toxicology Letters. 164: S169. DOI: 10.1016/J.Toxlet.2006.07.010 |
0.305 |
|
| 2005 |
Windal I, Denison MS, Birnbaum LS, Van Wouwe N, Baeyens W, Goeyens L. Chemically activated luciferase gene expression (CALUX) cell bioassay analysis for the estimation of dioxin-like activity: critical parameters of the CALUX procedure that impact assay results. Environmental Science & Technology. 39: 7357-64. PMID 16245802 DOI: 10.1021/Es0504993 |
0.419 |
|
| 2005 |
Jeong SH, Cho JH, Park JM, Denison MS. Rapid bioassay for the determination of dioxins and dioxin-like PCDFs and PCBs in meat and animal feeds. Journal of Analytical Toxicology. 29: 156-62. PMID 15842757 DOI: 10.1093/Jat/29.3.156 |
0.336 |
|
| 2005 |
Hall LC, Rogers JM, Denison MS, Johnson ML. Identification of the herbicide Surflan and its active ingredient oryzalin, a dinitrosulfonamide, as xenoestrogens. Archives of Environmental Contamination and Toxicology. 48: 201-8. PMID 15696347 DOI: 10.1007/S00244-003-0164-8 |
0.427 |
|
| 2004 |
Denison MS, Zhao B, Baston DS, Clark GC, Murata H, Han D. Recombinant cell bioassay systems for the detection and relative quantitation of halogenated dioxins and related chemicals. Talanta. 63: 1123-33. PMID 18969542 DOI: 10.1016/J.Talanta.2004.05.032 |
0.794 |
|
| 2004 |
Peters AK, van Londen K, Bergman A, Bohonowych J, Denison MS, van den Berg M, Sanderson JT. Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, HepG2, and H4IIE cells Toxicological Sciences. 82: 488-496. PMID 15456928 DOI: 10.1093/Toxsci/Kfh284 |
0.781 |
|
| 2004 |
Sanderson JT, Hordijk J, Denison MS, Springsteel MF, Nantz MH, van den Berg M. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 82: 70-9. PMID 15319488 DOI: 10.1093/Toxsci/Kfh257 |
0.342 |
|
| 2004 |
Brown DJ, Van Overmeire I, Goeyens L, Denison MS, De Vito MJ, Clark GC. Analysis of Ah receptor pathway activation by brominated flame retardants. Chemosphere. 55: 1509-18. PMID 15099731 DOI: 10.1016/J.Chemosphere.2003.10.019 |
0.483 |
|
| 2004 |
Han D, Nagy SR, Denison MS. Comparison of recombinant cell bioassays for the detection of Ah receptor agonists. Biofactors (Oxford, England). 20: 11-22. PMID 15096657 DOI: 10.1002/Biof.5520200102 |
0.381 |
|
| 2004 |
Knockaert M, Blondel M, Bach S, Leost M, Elbi C, Hager GL, Nagy SR, Han D, Denison M, Ffrench M, Ryan XP, Magiatis P, Polychronopoulos P, Greengard P, Skaltsounis L, et al. Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins. Oncogene. 23: 4400-12. PMID 15077192 DOI: 10.1038/Sj.Onc.1207535 |
0.412 |
|
| 2003 |
Monk SA, Denison MS, Rice RH. Reversible stepwise negative regulation of CYP1A1 in cultured rat epidermal cells. Archives of Biochemistry and Biophysics. 419: 158-69. PMID 14592459 DOI: 10.1016/J.Abb.2003.09.004 |
0.437 |
|
| 2003 |
Jeuken A, Keser BJ, Khan E, Brouwer A, Koeman J, Denison MS. Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits. Journal of Agricultural and Food Chemistry. 51: 5478-87. PMID 12926901 DOI: 10.1021/Jf030252U |
0.748 |
|
| 2003 |
Arrieta DE, Ontiveros CC, Li WW, Garcia JH, Denison MS, McDonald JD, Burchiel SW, Washburn BS. Aryl hydrocarbon receptor-mediated activity of particulate organic matter from the Paso del Norte airshed along the U.S.-Mexico border. Environmental Health Perspectives. 111: 1299-305. PMID 12896850 DOI: 10.1289/Ehp.6058 |
0.36 |
|
| 2003 |
Denison MS, Nagy SR. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annual Review of Pharmacology and Toxicology. 43: 309-34. PMID 12540743 DOI: 10.1146/Annurev.Pharmtox.43.100901.135828 |
0.544 |
|
| 2002 |
Denison MS, Rogers JM, Rushing SR, Jones CL, Tetangco SC, Heath-Pagliuso S. Analysis of the aryl hydrocarbon receptor (AhR) signal transduction pathway. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit4.8. PMID 20945300 DOI: 10.1002/0471140856.Tx0408S11 |
0.804 |
|
| 2002 |
Lashley MR, Niedzinski EJ, Rogers JM, Denison MS, Nantz MH. Synthesis and estrogen receptor affinity of a 4-hydroxytamoxifen-labeled ligand for diagnostic imaging. Bioorganic & Medicinal Chemistry. 10: 4075-82. PMID 12413861 DOI: 10.1016/S0968-0896(02)00329-2 |
0.437 |
|
| 2002 |
Ziccardi MH, Gardner IA, Denison MS. Application of the luciferase recombinant cell culture bioassay system for the analysis of polycyclic aromatic hydrocarbons. Environmental Toxicology and Chemistry / Setac. 21: 2027-33. PMID 12371477 DOI: 10.1002/Etc.5620211004 |
0.424 |
|
| 2002 |
Han DH, Denison MS, Tachibana H, Yamada K. Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids. Bioscience, Biotechnology, and Biochemistry. 66: 1479-87. PMID 12224631 DOI: 10.1271/Bbb.66.1479 |
0.476 |
|
| 2002 |
Denison MS, Pandini A, Nagy SR, Baldwin EP, Bonati L. Ligand binding and activation of the Ah receptor. Chemico-Biological Interactions. 141: 3-24. PMID 12213382 DOI: 10.1016/S0009-2797(02)00063-7 |
0.505 |
|
| 2002 |
Nagy SR, Denison MS. Specificity of nuclear protein binding to a CYP1A1 negative regulatory element. Biochemical and Biophysical Research Communications. 296: 799-805. PMID 12200118 DOI: 10.1016/S0006-291X(02)00945-2 |
0.427 |
|
| 2002 |
Natarajan K, Overstreet JW, Rogers JM, Denison MS, Chen J, Lohstroh PN, McConnell DS, Lasley BL. Detection of xenoestrogens in serum after immunoprecipitation of endogenous steroidal estrogens. Environmental Health Perspectives. 110: 791-5. PMID 12153760 DOI: 10.1289/Ehp.02110791 |
0.319 |
|
| 2002 |
Rushing SR, Denison MS. The silencing mediator of retinoic acid and thyroid hormone receptors can interact with the aryl hydrocarbon (Ah) receptor but fails to repress Ah receptor-dependent gene expression. Archives of Biochemistry and Biophysics. 403: 189-201. PMID 12139968 DOI: 10.1016/S0003-9861(02)00233-3 |
0.829 |
|
| 2002 |
Ziccardi MH, Mazet JA, Gardner IA, Boyce WM, Denison MS. Validation of a cell culture bioassay for detection of petroleum exposure in mink (Mustela vison) as a model for detection in sea otters (Enhydra lutris). American Journal of Veterinary Research. 63: 963-8. PMID 12118676 DOI: 10.2460/Ajvr.2002.63.963 |
0.303 |
|
| 2002 |
Rogers JM, Denison MS. Analysis of the antiestrogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in human ovarian carcinoma BG-1 cells. Molecular Pharmacology. 61: 1393-403. PMID 12021401 DOI: 10.1124/Mol.61.6.1393 |
0.475 |
|
| 2002 |
Liu PC, Moreno-Aliaga MJ, Dunlap DY, Hu XM, Denison MS, Matsumura F. Correlation between the high expression of C/EBPbeta protein in F442A cells and their relative resistance to antiadipogenic action of TCDD in comparison to 3T3-L1 cells. Journal of Biochemical and Molecular Toxicology. 16: 70-83. PMID 11979424 DOI: 10.1002/Jbt.10020 |
0.337 |
|
| 2002 |
Nagy SR, Sanborn JR, Hammock BD, Denison MS. Development of a green fluorescent protein-based cell bioassay for the rapid and inexpensive detection and characterization of ah receptor agonists. Toxicological Sciences : An Official Journal of the Society of Toxicology. 65: 200-10. PMID 11812924 DOI: 10.1093/Toxsci/65.2.200 |
0.517 |
|
| 2002 |
Nagy SR, Liu G, Lam KS, Denison MS. Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry. 41: 861-8. PMID 11790108 DOI: 10.1021/Bi011373V |
0.494 |
|
| 2001 |
Seidel SD, Winters GM, Rogers WJ, Ziccardi MH, Li V, Keser B, Denison MS. Activation of the Ah receptor signaling pathway by prostaglandins Journal of Biochemical and Molecular Toxicology. 15: 187-196. PMID 11673847 DOI: 10.1002/Jbt.16 |
0.575 |
|
| 2001 |
Monk SA, Denison MS, Rice RH. Transient expression of CYP1A1 in rat epithelial cells cultured in suspension Archives of Biochemistry and Biophysics. 393: 154-162. PMID 11516172 DOI: 10.1006/Abbi.2001.2475 |
0.422 |
|
| 2001 |
Van Overmeire I, Clark GC, Brown DJ, Chu MD, Marcus Cooke W, Denison MS, Baeyens W, Srebrnik S, Goeyens L. Trace contamination with dioxin-like chemicals: Evaluation of bioassay-based TEQ determination for hazard assessment and regulatory responses Environmental Science and Policy. 4: 345-357. DOI: 10.1016/S1462-9011(01)00037-5 |
0.346 |
|
| 2000 |
Williams SN, Shih H, Guenette DK, Brackney W, Denison MS, Pickwell GV, Quattrochi LC. Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A gene expression. Chemico-Biological Interactions. 128: 211-29. PMID 11064004 DOI: 10.1016/S0009-2797(00)00204-0 |
0.511 |
|
| 2000 |
Seidel SD, Li V, Winter GM, Rogers WJ, Martinez EI, Denison MS. Ah receptor-based chemical screening bioassays: application and limitations for the detection of Ah receptor agonists. Toxicological Sciences : An Official Journal of the Society of Toxicology. 55: 107-15. PMID 10788565 DOI: 10.1093/Toxsci/55.1.107 |
0.527 |
|
| 2000 |
Ziccardi MH, Gardner IA, Denison MS. Development and modification of a recombinant cell bioassay to directly detect halogenated and polycyclic aromatic hydrocarbons in serum Toxicological Sciences. 54: 183-193. PMID 10746945 DOI: 10.1093/Toxsci/54.1.183 |
0.388 |
|
| 2000 |
Garrison PM, Rogers JM, Brackney WR, Denison MS. Effects of histone deacetylase inhibitors on the Ah receptor gene promoter Archives of Biochemistry and Biophysics. 374: 161-171. PMID 10666294 DOI: 10.1006/Abbi.1999.1620 |
0.438 |
|
| 2000 |
Garrison PM, Denison MS. Analysis of the murine AhR gene promoter Journal of Biochemical and Molecular Toxicology. 14: 1-10. PMID 10561076 DOI: 10.1002/(Sici)1099-0461(2000)14:1<1::Aid-Jbt1>3.0.Co;2-4 |
0.442 |
|
| 1999 |
Seidel SD, Denison MS. Differential gene expression in wild-type and Arnt-defective mouse hepatoma (Hepa1c1c7) cells Toxicological Sciences. 52: 217-225. PMID 10630574 DOI: 10.1093/Toxsci/52.2.217 |
0.405 |
|
| 1999 |
Tian Y, Ke S, Denison MS, Rabson AB, Gallo MA. Ah receptor and NF-κB interactions, a potential mechanism for dioxin toxicity Journal of Biological Chemistry. 274: 510-515. PMID 9867872 DOI: 10.1074/Jbc.274.1.510 |
0.388 |
|
| 1999 |
Levine SL, Oris JT, Denison MS. Modulation of CYP1A expression in rainbow trout by a technical grade formulation of propiconazole Environmental Toxicology and Chemistry. 18: 2565-2573. DOI: 10.1002/Etc.5620181125 |
0.421 |
|
| 1998 |
Denison MS, Phelan D, Winter GM, Ziccardi MH. Carbaryl, a carbamate insecticide, is a ligand for the hepatic Ah (dioxin) receptor. Toxicology and Applied Pharmacology. 152: 406-14. PMID 9853009 DOI: 10.1006/Taap.1998.9999 |
0.559 |
|
| 1998 |
Denison MS, Heath-Pagliuso S. The Ah receptor: A regulator of the biochemical and toxicological actions of structurally diverse chemicals Bulletin of Environmental Contamination and Toxicology. 61: 557-568. PMID 9841714 DOI: 10.1007/Pl00002973 |
0.378 |
|
| 1998 |
Phelan D, Winter GM, Rogers WJ, Lam JC, Denison MS. Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin. Archives of Biochemistry and Biophysics. 357: 155-63. PMID 9721195 DOI: 10.1006/Abbi.1998.0814 |
0.569 |
|
| 1998 |
Besselink HT, Denison MS, Hahn ME, Karchner SI, Vethaak AD, Koeman JH, Brouwer A. Low inducibility of cyp1a activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): Characterization of the Ah receptor and the role of CYP1A inhibition Toxicological Sciences. 43: 161-171. PMID 9710958 DOI: 10.1006/Toxs.1998.2455 |
0.431 |
|
| 1998 |
Heath-Pagliuso S, Rogers WJ, Tullis K, Seidel SD, Cenijn PH, Brouwer A, Denison MS. Activation of the Ah receptor by tryptophan and tryptophan metabolites Biochemistry. 37: 11508-11515. PMID 9708986 DOI: 10.1021/Bi980087P |
0.583 |
|
| 1998 |
Phelan DM, Brackney WR, Denison MS. The Ah receptor can bind ligand in the absence of receptor-associated heat-shock protein 90 Archives of Biochemistry and Biophysics. 353: 47-54. PMID 9578599 DOI: 10.1006/Abbi.1997.0614 |
0.504 |
|
| 1997 |
Washburn BS, Rein KS, Baden DG, Walsh PJ, Hinton DE, Tullis K, Denison MS. Brevetoxin-6 (PbTx-6), a nonaromatic marine neurotoxin, is a ligand of the aryl hydrocarbon receptor Archives of Biochemistry and Biophysics. 343: 149-156. PMID 9224724 DOI: 10.1006/Abbi.1997.0149 |
0.524 |
|
| 1997 |
Murk AJ, Leonards PEG, Bulder AS, Jonas AS, Rozemeijer MJC, Denison MS, Koeman JH, Brouwer A. The calux (chemical-activated luciferase expression) assay adapted and validated for measuring TCDD equivalents in blood plasma Environmental Toxicology and Chemistry. 16: 1583-1589. DOI: 10.1002/Etc.5620160804 |
0.334 |
|
| 1997 |
Richter CA, Tieber VL, Denison MS, Giesy JP. An in vitro rainbow trout cell bioassay for aryl hydrocarbon receptor- mediated toxins Environmental Toxicology and Chemistry. 16: 543-550. DOI: 10.1002/Etc.5620160321 |
0.47 |
|
| 1996 |
Gebremichael A, Tullis K, Denison MS, Cheek JM, Pinkerton KE. Ah-receptor-dependent modulation of gene expression by aged and diluted sidestream cigarette smoke Toxicology and Applied Pharmacology. 141: 76-83. PMID 8917678 DOI: 10.1016/S0041-008X(96)80011-1 |
0.462 |
|
| 1996 |
Villalobos SA, Anderson MJ, Denison MS, Hinton DE, Tullis K, Kennedy IM, Jones AD, Chang DP, Yang G, Kelly P. Dioxinlike properties of a trichloroethylene combustion-generated aerosol. Environmental Health Perspectives. 104: 734-43. PMID 8841759 DOI: 10.1289/Ehp.96104734 |
0.427 |
|
| 1996 |
Garrison PM, Tullis K, Aarts JMMJG, Brouwer A, Giesy JP, Denison MS. Species-Specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals Fundamental and Applied Toxicology. 30: 194-203. PMID 8812265 DOI: 10.1093/Toxsci/30.2.194 |
0.445 |
|
| 1996 |
Walsh AA, Tullis K, Rice RH, Denison MS. Identification of a novel cis-acting negative regulatory element affecting expression of the CYP1A1 gene in rat epidermal cells Journal of Biological Chemistry. 271: 22746-22753. PMID 8798449 DOI: 10.1074/Jbc.271.37.22746 |
0.488 |
|
| 1996 |
Balaguer P, Joyeux A, Denison MS, Vincent R, Gillesby BE, Zacharewski T. Assessing the estrogenic and dioxin-like activities of chemicals and complex mixtures using in vitro recombinant receptor-reporter gene assays Canadian Journal of Physiology and Pharmacology. 74: 216-222. PMID 8723035 DOI: 10.1139/Cjpp-74-2-216 |
0.465 |
|
| 1996 |
Sanderson JT, Aarts JMMJG, Brouwer A, Froese KL, Denison MS, Giesy JP. Comparison of Ah receptor-mediated luciferase and ethoxyresorufin-O-deethylase induction in H4IIE cells: Implications for their use as bioanalytical tools for the detection of polyhalogenated aromatic hydrocarbons Toxicology and Applied Pharmacology. 137: 316-325. PMID 8661358 DOI: 10.1006/Taap.1996.0086 |
0.439 |
|
| 1996 |
Kraemer SA, Arthur KA, Denison MS, Smith WL, DeWitt DL. Regulation of prostaglandin endoperoxide H synthase-2 expression by 2,3,7,8,-tetrachlorodibenzo-p-dioxin. Archives of Biochemistry and Biophysics. 330: 319-28. PMID 8660662 DOI: 10.1006/Abbi.1996.0259 |
0.425 |
|
| 1996 |
Murk AJ, Legler J, Denison MS, Giesy JP, Van De Guchte C, Brouwer A. Chemical-activated luciferase gene expression (CALUX): A novel in vitro bioassay for Ah receptor active compounds in sediments and pore water Toxicological Sciences. 33: 149-160. DOI: 10.1006/Faat.1996.0152 |
0.418 |
|
| 1995 |
Aarts JMMJG, Denison MS, Cox MA, Schalk MAC, Garrison PM, Tullis K, de Haan LHJ, Brouwer A. Species-specific antagonism of Ah receptor action by 2,2′,5,5′-tetrachloro- and 2,2′,3,3′,4,4′-hexachlorobiphenyl European Journal of Pharmacology: Environmental Toxicology And. 293: 463-474. PMID 8748700 DOI: 10.1016/0926-6917(95)90067-5 |
0.499 |
|
| 1995 |
Bank PA, Yao EF, Swanson HI, Tullis K, Denison MS. DNA Binding of the Transformed Guinea Pig Hepatic Ah Receptor Complex: Identification and Partial Characterization of 2 High-Affinity DNA-Binding Forms Archives of Biochemistry and Biophysics. 317: 439-448. PMID 7893161 DOI: 10.1006/Abbi.1995.1186 |
0.317 |
|
| 1995 |
Chen YH, Riby J, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regulation of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. The Journal of Biological Chemistry. 270: 22548-55. PMID 7673247 DOI: 10.1074/Jbc.270.38.22548 |
0.377 |
|
| 1995 |
Denison MS, Whitlock JP. Xenobiotic-inducible transcription of cytochrome P450 genes Journal of Biological Chemistry. 270: 18175-18178. PMID 7629130 DOI: 10.1074/Jbc.270.31.18175 |
0.328 |
|
| 1995 |
Brouwer A, Ahlborg UG, Van den Berg M, Birnbaum LS, Ruud Boersma E, Bosveld B, Denison MS, Earl Gray L, Hagmar L, Holene E, Huisman M, Jacobson SW, Jacobson JL, Koopman-Esseboom C, Koppe JG, et al. Functional aspects of developmental toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants European Journal of Pharmacology: Environmental Toxicology And. 293: 1-40. PMID 7545581 DOI: 10.1016/0926-6917(95)90015-2 |
0.327 |
|
| 1995 |
Newsted JL, Giesy JP, Ankley GT, Tillitt DE, Crawford RA, Gooch JW, Jones PD, Denison MS. Development of toxic equivalency factors for PCB congeners and the assessment of TCDD and PCB mixtures in rainbow trout Environmental Toxicology and Chemistry. 14: 861-871. DOI: 10.1002/Etc.5620140518 |
0.368 |
|
| 1994 |
Dehaan LHJ, Simons JWFA, Bos AT, Aarts JMMJG, Denison MS, Brouwer A. Inhibition of Intercellular Communication by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Dioxin-Like PCBs in Mouse Hepatoma Cells (Hepa1c1c7): Involvement of the Ah Receptor Toxicology and Applied Pharmacology. 129: 283-293. PMID 7992318 DOI: 10.1006/Taap.1994.1253 |
0.334 |
|
| 1994 |
El-Fouly MH, Richter C, Giesy JP, Denison MS. Production of a novel recombinant cell line for use as a bioassay system for detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals Environmental Toxicology and Chemistry. 13: 1581-1588. |
0.357 |
|
| 1993 |
Denison MS. Binding of transformed Ah receptor complex to a dioxin responsive transcriptional enhancer: Evidence for two distinct heteromeric DNA-binding forms Biochemistry®. 12841-12849. DOI: 10.1021/Bi00210A037 |
0.437 |
|
| 1992 |
Bank PA, Yao EF, Phelps CL, Harper PA, Denison MS. Species-specific binding of transformed Ah receptor to a dioxin responsive transcriptional enhancer European Journal of Pharmacology: Environmental Toxicology And. 228: 85-94. PMID 1332880 DOI: 10.1016/0926-6917(92)90016-6 |
0.346 |
|
| 1992 |
Harper PA, Giannone JV, Okey AB, Denison MS. In vitro transformation of the human Ah receptor and its binding to a dioxin response element Molecular Pharmacology. 42: 603-612. PMID 1331752 |
0.349 |
|
| 1991 |
Denison MS, Yao EF. Characterization of the interaction of transformed rat hepatic cytosolic Ah receptor with a dioxin responsive transcriptional enhancer Archives of Biochemistry and Biophysics. 284: 158-166. PMID 1846511 DOI: 10.1016/0003-9861(91)90278-Q |
0.381 |
|
| 1991 |
Helferich WG, Denison MS. Ultraviolet photoproducts of tryptophan can act as dioxin agonists Molecular Pharmacology. 40: 674-678. PMID 1658604 |
0.416 |
|
| 1990 |
Prokipcak RD, Denison MS, Okey AB. Nuclear Ah receptor from mouse hepatoma cells: Effect of partial proteolysis on relative molecular mass and DNA-binding properties Archives of Biochemistry and Biophysics. 283: 476-483. PMID 2177330 DOI: 10.1016/0003-9861(90)90670-T |
0.369 |
|
| 1990 |
Fisher JM, Wu L, Denison MS, Whitlock JP. Organization and function of a dioxin-responsive enhancer. The Journal of Biological Chemistry. 265: 9676-81. PMID 2161840 |
0.408 |
|
| 1990 |
Denison MS, Deal RM. The binding of transformed aromatic hydrocarbon (Ah) receptor to its DNA recognition site is not affected by metal depletion Molecular and Cellular Endocrinology. 69: 51-57. PMID 2157617 DOI: 10.1016/0303-7207(90)90088-P |
0.367 |
|
| 1989 |
Whitlock JP, Denison MS, Durrin LK, Fisher JM, Galeazzi DR, Jones PBC. Regulation of cytochrome p1-450 gene expression in mouse hepatoma cells by 2,3,7,8-tetrachloflodibenzo-p-dioxin Drug Metabolism Reviews. 20: 839-846. PMID 2806081 DOI: 10.3109/03602538909103583 |
0.33 |
|
| 1989 |
Denison MS, Vella LM, Okey AB. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver: lack of sensitivity to alkaline phosphatase when compared with that of glucocorticoid receptor. Archives of Biochemistry and Biophysics. 273: 458-65. PMID 2774562 DOI: 10.1016/0003-9861(89)90505-5 |
0.343 |
|
| 1989 |
Whitlock JP, Denison MS, Fisher JM, Shen ES. Induction of hepatic cytochrome P450 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Molecular Biology & Medicine. 6: 169-78. PMID 2693891 |
0.451 |
|
| 1989 |
Denison MS, Fisher JM, Whitlock JP. Protein-DNA interactions at recognition sites for the dioxin-Ah receptor complex. The Journal of Biological Chemistry. 264: 16478-82. PMID 2550446 |
0.375 |
|
| 1988 |
Denison MS, Fisher JM, Whitlock JP. The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis Journal of Biological Chemistry. 263: 17221-17224. PMID 2846558 |
0.385 |
|
| 1988 |
Denison MS, Fisher JM, Whitlock JP. Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer Proceedings of the National Academy of Sciences of the United States of America. 85: 2528-2532. PMID 2833743 DOI: 10.1073/Pnas.85.8.2528 |
0.475 |
|
| 1987 |
Denison MS, Vella LM, Okey AB. Structure and function of the Ah receptor: sulfhydryl groups required for binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to cytosolic receptor from rodent livers. Archives of Biochemistry and Biophysics. 252: 388-95. PMID 3028264 DOI: 10.1016/0003-9861(87)90045-2 |
0.355 |
|
| 1986 |
Denison MS, Vella LM, Okey AB. Hepatic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Partial stabilization by molybdate. The Journal of Biological Chemistry. 261: 10189-95. PMID 3015922 |
0.303 |
|
| 1986 |
Denison MS, Harper PA, Okey AB. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Codistribution of unoccupied receptor with cytosolic marker enzymes during fractionation of mouse liver, rat liver and cultured Hepa-1c1 cells European Journal of Biochemistry. 155: 223-229. PMID 3007122 DOI: 10.1111/J.1432-1033.1986.Tb09480.X |
0.38 |
|
| 1986 |
Denison MS, Okey AB, Hamilton JW, Bloom SE, Wilkinson CF. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: ontogeny in chick embryo liver. Journal of Biochemical Toxicology. 1: 39-49. PMID 2856072 DOI: 10.1002/Jbt.2570010305 |
0.415 |
|
| 1986 |
Denison MS, Wilkinson CF, Okey AB. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: Comparative studies in mammalian and nonmammalian species Chemosphere. 15: 1665-1672. DOI: 10.1016/0045-6535(86)90452-2 |
0.364 |
|
| 1985 |
Denison MS, Wilkinson CF. Identification of the Ah receptor in selected mammalian species and induction of aryl hydrocarbon hydroxylase. European Journal of Biochemistry / Febs. 147: 429-35. PMID 2982617 DOI: 10.1111/J.1432-1033.1985.Tb08767.X |
0.503 |
|
| 1985 |
Denison MS, Hamilton JW, Wilkinson CF. Comparative studies of aryl hydrocarbon hydroxylase and the Ah receptor in nonmammalian species. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 80: 319-24. PMID 2861016 DOI: 10.1016/0742-8413(85)90063-5 |
0.331 |
|
| 1985 |
Denison MS, Vella LM, Okey AB. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): Subunit dissociation and inactivation of ligand binding in conditions of high ionic strength Federation Proceedings. 44: No. 6225. |
0.328 |
|
| 1984 |
Denison MS, Fine J, Wilkinson CF. Protamine sulfate precipitation: a new assay for the Ah receptor. Analytical Biochemistry. 142: 28-36. PMID 6097142 DOI: 10.1016/0003-2697(84)90512-8 |
0.309 |
|
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