☰

Rebecca S. Shapiro, Ph.D. - Publications

Affiliations: 
2012 Molecular and Medical Genetics University of Toronto, Toronto, ON, Canada 
Area:
Microbiology Biology
Tree Info Similar researchers PubMed Report error

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Puumala E, Sychantha D, Lach E, Reeves S, Nabeela S, Fogal M, Nigam A, Johnson JW, Aspuru-Guzik A, Shapiro RS, Uppuluri P, Kalyaanamoorthy S, Magolan J, Whitesell L, Robbins N, et al. Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology. PMID 38402621 DOI: 10.1016/j.chembiol.2024.01.010  0.533
2024 Maroc L, Shaker H, Shapiro RS. Functional genetic characterization of stress tolerance and biofilm formation in () via a novel CRISPR activation system. Msphere. e0076123. PMID 38265239 DOI: 10.1128/msphere.00761-23  0.314
2023 Librais GMN, Jiang Y, Iqra R, Brandl CJ, Shapiro RS, Lajoie P. Evolutionary diversity of the control of the azole response by Tra1 across yeast species. G3 (Bethesda, Md.). PMID 37889998 DOI: 10.1093/g3journal/jkad250  0.337
2023 Iyer KR, Li SC, Revie NM, Lou JW, Duncan D, Fallah S, Sanchez H, Skulska I, Ušaj MM, Safizadeh H, Larsen B, Wong C, Aman A, Kiyota T, Yoshimura M, ... ... Shapiro RS, et al. Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity. Cell Chemical Biology. PMID 37369212 DOI: 10.1016/j.chembiol.2023.06.005  0.755
2022 Puumala E, Zaslaver O, Chen A, Duncan D, Fogal M, Shapiro RS, Mazhab-Jafari MT, Whitesell L, Montenegro-Burke JR, Robbins N, Cowen LE. The Trisubstituted Isoxazole MMV688766 Exerts Broad-Spectrum Activity against Drug-Resistant Fungal Pathogens through Inhibition of Lipid Homeostasis. Mbio. e0273022. PMID 36300931 DOI: 10.1128/mbio.02730-22  0.771
2022 Case NT, Berman J, Blehert DS, Cramer RA, Cuomo C, Currie CR, Ene IV, Fisher MC, Fritz-Laylin LK, Gerstein AC, Glass NL, Gow NAR, Gurr SJ, Hittinger CT, Hohl TM, ... ... Shapiro RS, et al. The future of fungi: threats and opportunities. G3 (Bethesda, Md.). PMID 36179219 DOI: 10.1093/g3journal/jkac224  0.692
2022 Revie NM, Iyer KR, Maxson ME, Zhang J, Yan S, Fernandes CM, Meyer KJ, Chen X, Skulska I, Fogal M, Sanchez H, Hossain S, Li S, Yashiroda Y, Hirano H, ... ... Shapiro RS, et al. Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation. Nature Communications. 13: 3634. PMID 35752611 DOI: 10.1038/s41467-022-31308-1  0.735
2021 Razzaq I, Berg MD, Jiang Y, Genereaux J, Uthayakumar D, Kim GH, Agyare-Tabbi M, Halder V, Brandl CJ, Lajoie P, Shapiro RS. The SAGA and NuA4 component Tra1 regulates Candida albicans drug resistance and pathogenesis. Genetics. 219. PMID 34849885 DOI: 10.1093/genetics/iyab131  0.364
2021 Rosiana S, Zhang L, Kim GH, Revtovich AV, Uthayakumar D, Sukumaran A, Geddes-McAlister J, Kirienko NV, Shapiro RS. Comprehensive genetic analysis of adhesin proteins and their role in virulence of Candida albicans. Genetics. 217. PMID 33724419 DOI: 10.1093/genetics/iyab003  0.317
2020 Horianopoulos LC, Gluck-Thaler E, Benoit Gelber I, Cowen LE, Geddes-McAlister J, Landry CR, Schwartz IS, Scott JA, Sellam A, Sheppard DC, Spribille T, Subramaniam R, Walker AK, Harris SD, Shapiro RS, et al. The Canadian Fungal Research Network: current challenges and future opportunities. Canadian Journal of Microbiology. PMID 32717148 DOI: 10.1139/Cjm-2020-0263  0.59
2020 Mei Y, Jiang T, Zou Y, Wang Y, Zhou J, Li J, Liu L, Tan J, Wei L, Li J, Dai H, Peng Y, Zhang L, Lopez-Ribot JL, Shapiro RS, et al. FDA Approved Drug Library Screening Identifies Robenidine as a Repositionable Antifungal. Frontiers in Microbiology. 11: 996. PMID 32582050 DOI: 10.3389/Fmicb.2020.00996  0.433
2020 Mohammadinejad R, Biagioni A, Arunkumar G, Shapiro R, Chang KC, Sedeeq M, Taiyab A, Hashemabadi M, Pardakhty A, Mandegary A, Thiery JP, Aref AR, Azimi I. EMT signaling: potential contribution of CRISPR/Cas gene editing. Cellular and Molecular Life Sciences : Cmls. PMID 32008085 DOI: 10.1007/S00018-020-03449-3  0.322
2019 Thomson GJ, Hernon C, Austriaco N, Shapiro RS, Belenky P, Bennett RJ. Metabolism-induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells. The Embo Journal. e101597. PMID 31448850 DOI: 10.15252/Embj.2019101597  0.325
2019 Halder V, Porter CBM, Chavez A, Shapiro RS. Author Correction: Design, execution, and analysis of CRISPR-Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans. Nature Protocols. PMID 30976123 DOI: 10.1038/S41596-019-0157-3  0.3
2019 Sharma J, Rosiana S, Razzaq I, Shapiro RS. Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Pathogens. Journal of Fungi (Basel, Switzerland). 5. PMID 30795580 DOI: 10.3390/Jof5010017  0.444
2019 Halder V, Porter CBM, Chavez A, Shapiro RS. Design, execution, and analysis of CRISPR-Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans. Nature Protocols. PMID 30737491 DOI: 10.1038/S41596-018-0122-6  0.351
2019 Polvi EJ, Veri AO, Liu Z, Hossain S, Hyde S, Kim SH, Tebbji F, Sellam A, Todd RT, Xie JL, Lin ZY, Wong CJ, Shapiro RS, Whiteway M, Robbins N, et al. Functional divergence of a global regulatory complex governing fungal filamentation. Plos Genetics. 15: e1007901. PMID 30615616 DOI: 10.1371/Journal.Pgen.1007901  0.736
2018 Geddes-McAlister J, Shapiro RS. New pathogens, new tricks: emerging, drug-resistant fungal pathogens and future prospects for antifungal therapeutics. Annals of the New York Academy of Sciences. PMID 29762860 DOI: 10.1111/Nyas.13739  0.444
2018 Shapiro RS, Chavez A, Collins JJ. CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms. Nature Reviews. Microbiology. PMID 29599458 DOI: 10.1038/S41579-018-0002-7  0.303
2018 Veri AO, Miao Z, Shapiro RS, Tebbji F, O'Meara TR, Kim SH, Colazo J, Tan K, Vyas VK, Whiteway M, Robbins N, Wong KH, Cowen LE. Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space. Plos Genetics. 14: e1007270. PMID 29590106 DOI: 10.1371/Journal.Pgen.1007270  0.767
2017 Shapiro RS, Chavez A, Porter CBM, Hamblin M, Kaas CS, DiCarlo JE, Zeng G, Xu X, Revtovich AV, Kirienko NV, Wang Y, Church GM, Collins JJ. A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans. Nature Microbiology. PMID 29062088 DOI: 10.1038/S41564-017-0043-0  0.375
2016 Cohen NR, Ross CA, Jain S, Shapiro RS, Gutierrez A, Belenky P, Li H, Collins JJ. A role for the bacterial GATC methylome in antibiotic stress survival. Nature Genetics. PMID 26998690 DOI: 10.1038/Ng.3530  0.37
2015 Shapiro RS. Antimicrobial-induced DNA damage and genomic instability in microbial pathogens. Plos Pathogens. 11: e1004678. PMID 25811381 DOI: 10.1371/Journal.Ppat.1004678  0.392
2012 Shapiro RS, Ryan O, Boone C, Cowen LE. Regulatory circuitry governing morphogenesis in Saccharomyces cerevisiae and Candida albicans. Cell Cycle (Georgetown, Tex.). 11: 4294-5. PMID 23095675 DOI: 10.4161/Cc.22608  0.655
2012 Shapiro RS, Cowen LE. Thermal control of microbial development and virulence: molecular mechanisms of microbial temperature sensing. Mbio. 3. PMID 23033469 DOI: 10.1128/Mbio.00238-12  0.628
2012 Ryan O, Shapiro RS, Kurat CF, Mayhew D, Baryshnikova A, Chin B, Lin ZY, Cox MJ, Vizeacoumar F, Cheung D, Bahr S, Tsui K, Tebbji F, Sellam A, Istel F, et al. Global gene deletion analysis exploring yeast filamentous growth. Science (New York, N.Y.). 337: 1353-6. PMID 22984072 DOI: 10.1126/Science.1224339  0.61
2012 Shapiro RS, Zaas AK, Betancourt-Quiroz M, Perfect JR, Cowen LE. The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance. Plos One. 7: e44734. PMID 22970302 DOI: 10.1371/Journal.Pone.0044734  0.661
2012 Shapiro RS, Cowen LE. Uncovering cellular circuitry controlling temperature-dependent fungal morphogenesis. Virulence. 3: 400-4. PMID 22722238 DOI: 10.4161/Viru.20979  0.645
2012 Diezmann S, Michaut M, Shapiro RS, Bader GD, Cowen LE. Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry. Plos Genetics. 8: e1002562. PMID 22438817 DOI: 10.1371/Journal.Pgen.1002562  0.625
2012 Shapiro RS, Sellam A, Tebbji F, Whiteway M, Nantel A, Cowen LE. Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise. Current Biology : Cb. 22: 461-70. PMID 22365851 DOI: 10.1016/J.Cub.2012.01.062  0.663
2012 Senn H, Shapiro RS, Cowen LE. Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans. Molecular Biology of the Cell. 23: 268-83. PMID 22090345 DOI: 10.1091/Mbc.E11-08-0729  0.63
2011 Shapiro RS, Robbins N, Cowen LE. Regulatory circuitry governing fungal development, drug resistance, and disease. Microbiology and Molecular Biology Reviews : Mmbr. 75: 213-67. PMID 21646428 DOI: 10.1128/Mmbr.00045-10  0.76
2011 Leach MD, Tyc K, Shapiro R, Cowen L, Klipp E, Brown AJ. Modelling the regulation of thermal adaptation by Hsf1 and Hsp90 in Candida albicans F1000research. 2. DOI: 10.7490/F1000Research.1452.1  0.573
2010 Shapiro RS, Cowen L. Coupling temperature sensing and development: Hsp90 regulates morphogenetic signalling in Candida albicans. Virulence. 1: 45-8. PMID 21178413 DOI: 10.4161/Viru.1.1.10320  0.65
2009 Shapiro RS, Uppuluri P, Zaas AK, Collins C, Senn H, Perfect JR, Heitman J, Cowen LE. Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling. Current Biology : Cb. 19: 621-9. PMID 19327993 DOI: 10.1016/J.Cub.2009.03.017  0.673
Show low-probability matches.