Bernd Antkowiak - Publications

Max Planck Institute for Biological Cybernetics, Tübingen, Baden-Württemberg, Germany 

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Drexler B, Grenz J, Grasshoff C, Antkowiak B. Allopregnanolone Enhances GABAergic Inhibition in Spinal Motor Networks. International Journal of Molecular Sciences. 21. PMID 33036451 DOI: 10.3390/ijms21197399  0.64
2020 Kreuzer M, Butovas S, García PS, Schneider G, Schwarz C, Rudolph U, Antkowiak B, Drexler B. Propofol Affects Cortico-Hippocampal Interactions via β3 Subunit-Containing GABA Receptors. International Journal of Molecular Sciences. 21. PMID 32823959 DOI: 10.3390/ijms21165844  0.64
2020 Drexler B, Seeger T, Worek F, Thiermann H, Antkowiak B, Grasshoff C. Impact of soman and acetylcholine on the effects of propofol in cultured cortical networks. Toxicology Letters. PMID 31954869 DOI: 10.1016/j.toxlet.2020.01.012  0.64
2019 Kreuzer M, García PS, Brucklacher-Waldert V, Claassen R, Schneider G, Antkowiak B, Drexler B. Diazepam and ethanol differently modulate neuronal activity in organotypic cortical cultures. Bmc Neuroscience. 20: 58. PMID 31823754 DOI: 10.1186/s12868-019-0540-6  0.64
2019 Hofmann JI, Schwarz C, Rudolph U, Antkowiak B. Effects of Diazepam on Low-Frequency and High-Frequency Electrocortical γ-Power Mediated by α1- and α2-GABA Receptors. International Journal of Molecular Sciences. 20. PMID 31315211 DOI: 10.3390/ijms20143486  0.64
2019 Antkowiak B, Rammes G. GABA(A) receptor-targeted drug development - New perspectives in perioperative anesthesia. Expert Opinion On Drug Discovery. PMID 30912680 DOI: 10.1080/17460441.2019.1599356  1
2018 Neumann E, Rudolph U, Knutson DE, Li G, Cook JM, Hentschke H, Antkowiak B, Drexler B. Zolpidem Activation of Alpha 1-Containing GABA Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons. Frontiers in Pharmacology. 9: 1523. PMID 30687091 DOI: 10.3389/fphar.2018.01523  0.72
2018 Drexler B, Seeger T, Worek F, Thiermann H, Antkowiak B, Grasshoff C. Midazolam is effective to reduce cortical network activity in organotypic cultures during severe cholinergic overstimulation with soman. Toxicology Letters. PMID 30165091 DOI: 10.1016/j.toxlet.2018.08.016  0.64
2017 Balk M, Hentschke H, Rudolph U, Antkowiak B, Drexler B. Differential depression of neuronal network activity by midazolam and its main metabolite 1-hydroxymidazolam in cultured neocortical slices. Scientific Reports. 7: 3503. PMID 28615640 DOI: 10.1038/s41598-017-03154-5  0.72
2016 Drexler B, Balk M, Antkowiak B. Synergistic Modulation of γ-Aminobutyric Acid Type A Receptor-Mediated Synaptic Inhibition in Cortical Networks by Allopregnanolone and Propofol. Anesthesia and Analgesia. PMID 27529315 DOI: 10.1213/ANE.0000000000001429  0.64
2016 Antkowiak B, Rudolph U. New insights in the systemic and molecular underpinnings of general anesthetic actions mediated by γ-aminobutyric acid A receptors. Current Opinion in Anaesthesiology. PMID 27168087 DOI: 10.1097/ACO.0000000000000358  0.64
2015 Weimer I, Worek F, Seeger T, Thiermann H, Grasshoff C, Antkowiak B, Balk M. Anesthetic actions of thiopental remain largely unaffected during cholinergic overstimulation in cultured cortical networks. Toxicology Letters. PMID 26325215 DOI: 10.1016/j.toxlet.2015.08.1106  1
2015 Eckle VS, Balk M, Thiermann H, Antkowiak B, Grasshoff C. Botulinum toxin B increases intrinsic muscle activity in organotypic spinal cord-skeletal muscle co-cultures. Toxicology Letters. PMID 26260118 DOI: 10.1016/j.toxlet.2015.08.003  1
2015 Weimer I, Worek F, Seeger T, Thiermann H, Eckle VS, Grasshoff C, Antkowiak B. Self-regeneration of neuromuscular function following soman and VX poisoning in spinal cord-skeletal muscle cocultures. Toxicology Letters. PMID 26256036 DOI: 10.1016/j.toxlet.2015.08.004  1
2015 Antkowiak B. Closing the gap between the molecular and systemic actions of anesthetic agents. Advances in Pharmacology (San Diego, Calif.). 72: 229-62. PMID 25600373 DOI: 10.1016/bs.apha.2014.10.009  1
2015 Eckle VS, Rudolph U, Antkowiak B, Grasshoff C. Propofol modulates phasic and tonic GABAergic currents in spinal ventral horn interneurones. British Journal of Anaesthesia. 114: 491-8. PMID 25150989 DOI: 10.1093/bja/aeu269  1
2014 Eckle VS, Grasshoff C, Mirakaj V, O'Neill PM, Berry NG, Leuwer M, Antkowiak B. 4-bromopropofol decreases action potential generation in spinal neurons by inducing a glycine receptor-mediated tonic conductance. British Journal of Pharmacology. 171: 5790-801. PMID 25131750 DOI: 10.1111/bph.12880  1
2014 Eckle VS, Drexler B, Grasshoff C, Seeger T, Thiermann H, Antkowiak B. Spinal cord--skeletal muscle cocultures detect muscle-relaxant action of botulinum neurotoxin A. Altex. 31: 433-40. PMID 25127438 DOI:  1
2014 Kreuzer M, Jordan D, Antkowiak B, Drexler B, Kochs EF, Schneider G. Brain electrical activity obeys Benford's law. Anesthesia and Analgesia. 118: 183-91. PMID 24356167 DOI: 10.1213/ANE.0000000000000015  1
2014 Eckle VS, Drexler B, Grasshoff C, Seeger T, Thiermann H, Antkowiak B. Spinal cord - Skeletal muscle cocultures detect muscle-relaxant action of botulinum neurotoxin A Archivos De Medicina Veterinaria. 46: 433-440. DOI: 10.14573/altex.1304291  1
2013 Razik DS, Hawellek DJ, Antkowiak B, Hentschke H. Impairment of GABA transporter GAT-1 terminates cortical recurrent network activity via enhanced phasic inhibition. Frontiers in Neural Circuits. 7: 141. PMID 24062646 DOI: 10.3389/fncir.2013.00141  1
2013 Eckle VS, Antkowiak B. ALX 1393 inhibits spontaneous network activity by inducing glycinergic tonic currents in the spinal ventral horn. Neuroscience. 253: 165-71. PMID 23994185 DOI: 10.1016/j.neuroscience.2013.08.042  1
2013 Drexler B, Thiermann H, Antkowiak B, Grasshoff C. Effects of succinylcholine in an organotypic spinal cord-skeletal muscle coculture of embryonic mice. Chemico-Biological Interactions. 206: 555-60. PMID 23838346 DOI: 10.1016/j.cbi.2013.06.021  1
2013 Drexler B, Kreuzer M, Jordan D, Antkowiak B, Schneider G. Sevoflurane-induced loss of consciousness is paralleled by a prominent modification of neural activity during cortical down-states. Neuroscience Letters. 548: 149-54. PMID 23721783 DOI: 10.1016/j.neulet.2013.05.040  1
2013 Eckle VS, Hauser S, Drexler B, Antkowiak B, Grasshoff C. Opposing actions of sevoflurane on GABAergic and glycinergic synaptic inhibition in the spinal ventral horn. Plos One. 8: e60286. PMID 23565218 DOI: 10.1371/journal.pone.0060286  1
2013 Drexler B, Zinser S, Huang S, Poe MM, Rudolph U, Cook JM, Antkowiak B. Enhancing the function of alpha5-subunit-containing GABAA receptors promotes action potential firing of neocortical neurons during up-states. European Journal of Pharmacology. 703: 18-24. PMID 23380687 DOI: 10.1016/j.ejphar.2013.01.034  1
2011 Drexler B, Zinser S, Seeger T, Thiermann H, Antkowiak B, Grasshoff C. Anaesthetic potency of diazepam is resistant to cholinergic overstimulation. Toxicology Letters. 206: 84-8. PMID 21699965 DOI: 10.1016/j.toxlet.2011.06.002  1
2011 Drexler B, Seeger T, Grasshoff C, Thiermann H, Antkowiak B. Long-term evaluation of organophosphate toxicity and antidotal therapy in co-cultures of spinal cord and muscle tissue. Toxicology Letters. 206: 89-93. PMID 21530620 DOI: 10.1016/j.toxlet.2011.04.010  1
2011 Drexler B, Antkowiak B, Engin E, Rudolph U. Identification and characterization of anesthetic targets by mouse molecular genetics approaches. Canadian Journal of Anaesthesia = Journal Canadien D'AnesthéSie. 58: 178-90. PMID 21174184 DOI: 10.1007/s12630-010-9414-1  1
2010 Drexler B, Hentschke H, Antkowiak B, Grasshoff C. Organotypic cultures as tools for testing neuroactive drugs - link between in-vitro and in-vivo experiments. Current Medicinal Chemistry. 17: 4538-50. PMID 21062252 DOI: 10.2174/092986710794183042  1
2010 Drexler B, Zinser S, Hentschke H, Antkowiak B. Diazepam decreases action potential firing of neocortical neurons via two distinct mechanisms. Anesthesia and Analgesia. 111: 1394-9. PMID 20889946 DOI: 10.1213/ANE.0b013e3181f9c035  1
2010 Kreuzer M, Hentschke H, Antkowiak B, Schwarz C, Kochs EF, Schneider G. Cross-approximate entropy of cortical local field potentials quantifies effects of anesthesia--a pilot study in rats. Bmc Neuroscience. 11: 122. PMID 20863382 DOI: 10.1186/1471-2202-11-122  1
2010 Drexler B, Antkowiak B, Thiermann H, Seeger T, Grasshoff C. Interactions between atropine and etomidate in cortical and spinal networks during cholinergic crisis. Toxicology Letters. 198: 342-7. PMID 20696220 DOI: 10.1016/j.toxlet.2010.07.016  1
2010 Butovas S, Rudolph U, Jurd R, Schwarz C, Antkowiak B. Activity patterns in the prefrontal cortex and hippocampus during and after awakening from etomidate anesthesia. Anesthesiology. 113: 48-57. PMID 20508498 DOI: 10.1097/ALN.0b013e3181dc1db7  1
2010 Grasshoff C, Antkowiak B. Organotypic cultures of spinal cord ventral horn are valuable tools for investigating immobility-related mechanisms in vitro. Anesthesia and Analgesia. 110: 638; author reply 63. PMID 20081142 DOI: 10.1213/ANE.0b013e3181c531c8  1
2010 Thiermann H, Seeger T, Gonder S, Herkert N, Antkowiak B, Zilker T, Eyer F, Worek F. Assessment of neuromuscular dysfunction during poisoning by organophosphorus compounds. Chemico-Biological Interactions. 187: 265-9. PMID 20036651 DOI: 10.1016/j.cbi.2009.12.027  1
2010 Drexler B, Antkowiak B, Thiermann H, Grasshoff C. Atropine increases sevoflurane potency in cortical but not spinal networks during cholinergic overstimulation. Toxicology. 268: 98-103. PMID 20004696 DOI: 10.1016/j.tox.2009.12.005  1
2009 Drexler B, Jurd R, Rudolph U, Antkowiak B. Distinct actions of etomidate and propofol at beta3-containing gamma-aminobutyric acid type A receptors. Neuropharmacology. 57: 446-55. PMID 19555700 DOI: 10.1016/j.neuropharm.2009.06.014  1
2008 Grasshoff C, Netzhammer N, Schweizer J, Antkowiak B, Hentschke H. Depression of spinal network activity by thiopental: shift from phasic to tonic GABA(A) receptor-mediated inhibition. Neuropharmacology. 55: 793-802. PMID 18619475 DOI: 10.1016/j.neuropharm.2008.06.026  1
2008 Zeller A, Jurd R, Lambert S, Arras M, Drexler B, Grashoff C, Antkowiak B, Rudolph U. Inhibitory ligand-gated ion channels as substrates for general anesthetic actions. Handbook of Experimental Pharmacology. 31-51. PMID 18175085 DOI: 10.1007/978-3-540-74806-9_2  1
2007 Grasshoff C, Jurd R, Rudolph U, Antkowiak B. Modulation of presynaptic beta3-containing GABAA receptors limits the immobilizing actions of GABAergic anesthetics. Molecular Pharmacology. 72: 780-7. PMID 17584992 DOI: 10.1124/mol.107.037648  1
2007 Grasshoff C, Drexler B, Hentschke H, Thiermann H, Antkowiak B. Cholinergic modulation of sevoflurane potency in cortical and spinal networks in vitro. Anesthesiology. 106: 1147-55. PMID 17525590 DOI: 10.1097/01.anes.0000267598.65120.f2  1
2007 Grasshoff C, Drexler B, Antkowiak B. Effects of cholinergic overstimulation on isoflurane potency and efficacy in cortical and spinal networks. Toxicology. 229: 206-13. PMID 17141935 DOI: 10.1016/j.tox.2006.10.017  1
2007 Grasshoff C, Thiermann H, Antkowiak B. Anaesthesia in patients suffering from organophosphorus intoxication--interactions between general anaesthetics and acetylcholine in cortical networks in vitro. Toxicology. 233: 214-22. PMID 17030394 DOI: 10.1016/j.tox.2006.09.001  1
2006 Grasshoff C, Drexler B, Rudolph U, Antkowiak B. Anaesthetic drugs: linking molecular actions to clinical effects. Current Pharmaceutical Design. 12: 3665-79. PMID 17073666 DOI: 10.2174/138161206778522038  1
2006 Grasshoff C, Antkowiak B. Effects of isoflurane and enflurane on GABAA and glycine receptors contribute equally to depressant actions on spinal ventral horn neurones in rats. British Journal of Anaesthesia. 97: 687-94. PMID 16973644 DOI: 10.1093/bja/ael239  1
2006 Drexler B, Jurd R, Rudolph U, Antkowiak B. Dual actions of enflurane on postsynaptic currents abolished by the gamma-aminobutyric acid type A receptor beta3(N265M) point mutation. Anesthesiology. 105: 297-304. PMID 16871063 DOI: 10.1097/00000542-200608000-00012  1
2006 Drexler B, Grasshoff C, Rudolph U, Unertl K, Antkowiak B. [The GABA(A) receptor family: possibilities for the development of better anesthetics]. Der Anaesthesist. 55: 287-95. PMID 16315024 DOI: 10.1007/s00101-005-0950-y  1
2005 Grasshoff C, Rudolph U, Antkowiak B. Molecular and systemic mechanisms of general anaesthesia: the 'multi-site and multiple mechanisms' concept. Current Opinion in Anaesthesiology. 18: 386-91. PMID 16534263 DOI: 10.1097/  1
2005 Antkowiak B. The "anesthetic cascade": fact or fiction? Anesthesiology. 103: 904-5; author reply . PMID 16192794  1
2005 Drexler B, Roether CL, Jurd R, Rudolph U, Antkowiak B. Opposing actions of etomidate on cortical theta oscillations are mediated by different gamma-aminobutyric acid type A receptor subtypes. Anesthesiology. 102: 346-52. PMID 15681950 DOI: 10.1097/00000542-200502000-00017  1
2005 Hentschke H, Schwarz C, Antkowiak B. Neocortex is the major target of sedative concentrations of volatile anaesthetics: strong depression of firing rates and increase of GABAA receptor-mediated inhibition. The European Journal of Neuroscience. 21: 93-102. PMID 15654846 DOI: 10.1111/j.1460-9568.2004.03843.x  1
2005 Jurd R, Arras M, Zeller A, Lambert S, Lazaris A, Crestani F, Drexler B, Siegwart R, Vogt KE, Antkowiak B, Rudolph U. β3-containing GABAA receptors mediate the immobilizing and, in part, the hypnotic actions of etomidate and propofol International Congress Series. 1283: 143-148. DOI: 10.1016/j.ics.2005.07.076  1
2004 Grasshoff C, Antkowiak B. Propofol and sevoflurane depress spinal neurons in vitro via different molecular targets. Anesthesiology. 101: 1167-76. PMID 15505453 DOI: 10.1097/00000542-200411000-00017  1
2004 Rudolph U, Antkowiak B. Molecular and neuronal substrates for general anaesthetics. Nature Reviews. Neuroscience. 5: 709-20. PMID 15322529 DOI: 10.1038/nrn1496  1
2003 Heck D, Borst A, Antkowiak B. Passive spatial and temporal integration of excitatory synaptic inputs in cerebellar Purkinje cells of young rats. Neuroscience Letters. 341: 79-83. PMID 12676348 DOI: 10.1016/S0304-3940(03)00132-0  1
2003 Jurd R, Arras M, Lambert S, Drexler B, Siegwart R, Crestani F, Zaugg M, Vogt KE, Ledermann B, Antkowiak B, Rudolph U. General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 250-2. PMID 12475885 DOI: 10.1096/fj.02-0611fje  1
2002 Antkowiak B. In vitro networks: cortical mechanisms of anaesthetic action. British Journal of Anaesthesia. 89: 102-11. PMID 12173223 DOI: 10.1093/bja/aef154  1
2001 Antkowiak B. How do general anaesthetics work? Die Naturwissenschaften. 88: 201-13. PMID 11482433 DOI: 10.1007/s001140100230  1
2001 Antkowiak B. [Cerebral effects of volatile anesthetics--what do we really know?]. AnäSthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : Ains. 36: 365-7. PMID 11475630 DOI: 10.1055/s-2001-14809-4  1
2000 Antkowiak B, Kirschfeld K. [Neural mechanisms of anesthesia]. AnäSthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : Ains. 35: 731-43. PMID 11194514 DOI: 10.1055/s-2000-8935  1
2000 Antkowiak B, Hentschke H. [Effects of benzodiazepines and general anesthetics on the GABA A receptor: where are the differences?]. AnäSthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : Ains. 35: 593-5. PMID 11050966 DOI: 10.1055/s-2000-7094-3  1
1999 Antkowiak B. Different actions of general anesthetics on the firing patterns of neocortical neurons mediated by the GABA(A) receptor. Anesthesiology. 91: 500-11. PMID 10443614 DOI: 10.1097/00000542-199908000-00025  1
1999 Hentschke H, Antkowiak B. NMDA receptor-mediated changes of spontaneous activity patterns in thalamocortical slice cultures. Brain Research. 830: 123-37. PMID 10350566 DOI: 10.1016/S0006-8993(99)01399-2  1
1998 Engelmann W, Antkowiak B. Ultradian rhythms in Desmodium. Chronobiology International. 15: 293-307. PMID 9706408  1
1998 Antkowiak B, Helfrich-Förster C. Effects of small concentrations of volatile anesthetics on action potential firing of neocortical neurons in vitro. Anesthesiology. 88: 1592-605. PMID 9637654 DOI: 10.1097/00000542-199806000-00024  1
1997 Antkowiak B, Hentschke H, Kirschfeld K. Effects of volatile anaesthetics on spontaneous action potential firing of cerebellar Purkinje cells in vitro do not follow the Meyer-Overton rule. British Journal of Anaesthesia. 79: 617-24. PMID 9422902  1
1997 Felisberti F, Antkowiak B, Kirschfeld K. Effects of volatile anaesthetics on the membrane potential and ion channels of cultured neocortical astrocytes. Brain Research. 766: 56-65. PMID 9359587 DOI: 10.1016/S0006-8993(97)00554-4  1
1997 Antkowiak B, Hentschke H. Cellular mechanisms of gamma rhythms in rat neocortical brain slices probed by the volatile anaesthetic isoflurane. Neuroscience Letters. 231: 87-90. PMID 9291147 DOI: 10.1016/S0304-3940(97)00546-6  1
1997 Antkowiak B, Heck D. Effects of the volatile anesthetic enflurane on spontaneous discharge rate and GABA(A)-mediated inhibition of Purkinje cells in rat cerebellar slices. Journal of Neurophysiology. 77: 2525-38. PMID 9163374  1
1995 Antkowiak B, Engelmann W. Oscillations of apoplasmic K+ and H+ activities in Desmodium motorium (Houtt.) Merril. pulvini in relation to the membrane potential of motor cells and leaflet movements Planta: An International Journal of Plant Biology. 196: 350-356. DOI: 10.1007/BF00201395  1
1994 Rinast KA, Antkowiak B, Brinkmann K. Systems analysis of yeast glycolysis using perturbations of external pH: physiological parameters, non-parametric analysis, and general properties of the system dynamics. Bio Systems. 32: 211-21. PMID 7919118 DOI: 10.1016/0303-2647(94)90044-2  1
1992 Antkowiak B, Kirschfeld K. Enflurane is a potent inhibitor of high conductance Ca(2+)-activated K+ channels of Chara australis. Febs Letters. 313: 281-4. PMID 1446749 DOI: 10.1016/0014-5793(92)81209-5  1
1991 Antkowiak B, Mayer WE, Engelmann W. Oscillations of the membrane potential of pulvinar motor cells In Situ in relation to leaflet movements of Desmodium motorium Journal of Experimental Botany. 42: 901-910. DOI: 10.1093/jxb/42.7.901  1
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