| Year |
Citation |
Score |
| 2022 |
Paoletti P, Trautmann A, Marty A. Philippe Ascher (1936-2022). Neuron. 110: 3864-3865. PMID 36480941 DOI: 10.1016/j.neuron.2022.10.038 |
0.319 |
|
| 2022 |
Paoletti P, Trautmann A, Marty A. Remembering a giant of neuroscience. Nature. 611: 236. PMID 36347959 DOI: 10.1038/d41586-022-03584-w |
0.322 |
|
| 2022 |
Sikora J, Di Bisceglie Caballero S, Reiss D, Kieffer BL, Paoletti P, Jacob PY, Ouagazzal AM. Zn inhibits spatial memory and hippocampal place cell representation through high-affinity binding to the NMDA receptor GluN2A subunit. Iscience. 25: 105355. PMID 36325055 DOI: 10.1016/j.isci.2022.105355 |
0.36 |
|
| 2022 |
Bossi S, Dhanasobhon D, Ellis-Davies GCR, Frontera J, de Brito Van Velze M, Lourenço J, Murillo A, Luján R, Casado M, Perez-Otaño I, Bacci A, Popa D, Paoletti P, Rebola N. GluN3A excitatory glycine receptors control adult cortical and amygdalar circuits. Neuron. PMID 35700736 DOI: 10.1016/j.neuron.2022.05.016 |
0.572 |
|
| 2022 |
Morabito A, Zerlaut Y, Serraz B, Sala R, Paoletti P, Rebola N. Activity-dependent modulation of NMDA receptors by endogenous zinc shapes dendritic function in cortical neurons. Cell Reports. 38: 110415. PMID 35196488 DOI: 10.1016/j.celrep.2022.110415 |
0.313 |
|
| 2021 |
Thapaliya ER, Mony L, Sanchez R, Serraz B, Paoletti P, Ellis-Davies GCR. Photochemical control of drug efficacy - a comparison of uncaging and photoswitching ifenprodil on NMDA receptors. Chemphotochem. 5: 445-454. PMID 36540756 DOI: 10.1002/cptc.202000240 |
0.393 |
|
| 2021 |
Tian M, Stroebel D, Piot L, David M, Ye S, Paoletti P. GluN2A and GluN2B NMDA receptors use distinct allosteric routes. Nature Communications. 12: 4709. PMID 34354080 DOI: 10.1038/s41467-021-25058-9 |
0.505 |
|
| 2021 |
Geoffroy C, Paoletti P, Mony L. Positive allosteric modulation of NMDA receptors: mechanisms, physiological impact and therapeutic potential. The Journal of Physiology. PMID 34339523 DOI: 10.1113/JP280875 |
0.412 |
|
| 2021 |
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S. Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors. Neuron. PMID 34186027 DOI: 10.1016/j.neuron.2021.05.031 |
0.498 |
|
| 2021 |
Stroebel D, Mony L, Paoletti P. Glycine agonism in ionotropic glutamate receptors. Neuropharmacology. 193: 108631. PMID 34058193 DOI: 10.1016/j.neuropharm.2021.108631 |
0.494 |
|
| 2020 |
Stroebel D, Paoletti P. Architecture and function of NMDA receptors: an evolutionary perspective. The Journal of Physiology. PMID 32786006 DOI: 10.1113/Jp279028 |
0.523 |
|
| 2020 |
Shin W, Kim K, Serraz B, Cho YS, Kim D, Kang M, Lee EJ, Lee H, Bae YC, Paoletti P, Kim E. Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice. Plos Biology. 18: e3000717. PMID 32353004 DOI: 10.1371/Journal.Pbio.3000717 |
0.33 |
|
| 2020 |
Mony L, Paoletti P. Photocontrol of Metabotropic Glutamate Receptors: When One Agonist Is Not Enough, Make It Two. Neuron. 105: 395-397. PMID 32027826 DOI: 10.1016/J.Neuron.2020.01.013 |
0.5 |
|
| 2019 |
Sikora J, Kieffer BL, Paoletti P, Ouagazzal AM. Synaptic zinc contributes to motor and cognitive deficits in 6-hydroxydopamine mouse models of Parkinson's disease. Neurobiology of Disease. 134: 104681. PMID 31759136 DOI: 10.1016/J.Nbd.2019.104681 |
0.321 |
|
| 2019 |
Otsu Y, Darcq E, Pietrajtis K, Mátyás F, Schwartz E, Bessaih T, Abi Gerges S, Rousseau CV, Grand T, Dieudonné S, Paoletti P, Acsády L, Agulhon C, Kieffer BL, Diana MA. Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula. Science (New York, N.Y.). 366: 250-254. PMID 31601771 DOI: 10.1126/Science.Aax1522 |
0.762 |
|
| 2019 |
Paoletti P, Ellis-Davies GCR, Mourot A. Optical control of neuronal ion channels and receptors. Nature Reviews. Neuroscience. PMID 31289380 DOI: 10.1038/S41583-019-0197-2 |
0.422 |
|
| 2018 |
Yao L, Grand T, Hanson JE, Paoletti P, Zhou Q. Author Correction: Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity. Nature Communications. 9: 4887. PMID 30442888 DOI: 10.1038/S41467-018-07441-1 |
0.45 |
|
| 2018 |
Grand T, Abi Gerges S, David M, Diana MA, Paoletti P. Unmasking GluN1/GluN3A excitatory glycine NMDA receptors. Nature Communications. 9: 4769. PMID 30425244 DOI: 10.1038/S41467-018-07236-4 |
0.58 |
|
| 2018 |
Esmenjaud JB, Stroebel D, Chan K, Grand T, David M, Wollmuth LP, Taly A, Paoletti P. An inter-dimer allosteric switch controls NMDA receptor activity. The Embo Journal. PMID 30396997 DOI: 10.15252/Embj.201899894 |
0.528 |
|
| 2018 |
Yao L, Grand T, Hanson J, Paoletti P, Zhou Q. Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity. Nature Communications. 9: 4000. PMID 30275542 DOI: 10.1038/S41467-018-06512-7 |
0.422 |
|
| 2018 |
Stroebel D, Casado M, Paoletti P. Triheteromeric NMDA receptors: from structure to synaptic physiology. Current Opinion in Physiology. 2: 1-12. PMID 29682629 DOI: 10.1016/J.Cophys.2017.12.004 |
0.644 |
|
| 2018 |
Klippenstein V, Mony L, Paoletti P. Probing Ion Channel Structure and Function Using Light-Sensitive Amino Acids. Trends in Biochemical Sciences. PMID 29650383 DOI: 10.1016/J.Tibs.2018.02.012 |
0.321 |
|
| 2017 |
Ferreira JS, Papouin T, Ladépêche L, Yao A, Langlais VC, Bouchet D, Dulong J, Mothet JP, Sacchi S, Pollegioni L, Paoletti P, Oliet SHR, Groc L. Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses. Elife. 6. PMID 28598327 DOI: 10.7554/Elife.25492 |
0.52 |
|
| 2017 |
Klippenstein V, Hoppmann C, Ye S, Wang L, Paoletti P. Optocontrol of glutamate receptor activity by single side-chain photoisomerization. Elife. 6. PMID 28534738 DOI: 10.7554/Elife.25808 |
0.46 |
|
| 2017 |
Klippenstein V, Hoppmann C, Ye S, Wang L, Paoletti P. Author response: Optocontrol of glutamate receptor activity by single side-chain photoisomerization Elife. DOI: 10.7554/Elife.25808.028 |
0.457 |
|
| 2017 |
Ferreira JS, Papouin T, Ladépêche L, Yao A, Langlais VC, Bouchet D, Dulong J, Mothet J, Sacchi S, Pollegioni L, Paoletti P, Oliet SHR, Groc L. Author response: Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses Elife. DOI: 10.7554/Elife.25492.016 |
0.509 |
|
| 2016 |
Serraz B, Grand T, Paoletti P. Altered zinc sensitivity of NMDA receptors harboring clinically-relevant mutations. Neuropharmacology. PMID 27288002 DOI: 10.1016/J.Neuropharm.2016.06.008 |
0.481 |
|
| 2016 |
Stroebel D, Buhl DL, Knafels JD, Chanda PK, Green M, Sciabola S, Mony L, Paoletti P, Pandit J. A novel binding mode reveals two distinct classes of NMDA receptor GluN2B-selective antagonists. Molecular Pharmacology. PMID 26912815 DOI: 10.1124/Mol.115.103036 |
0.511 |
|
| 2016 |
Hackos DH, Lupardus PJ, Grand T, Chen Y, Wang TM, Reynen P, Gustafson A, Wallweber HJ, Volgraf M, Sellers BD, Schwarz JB, Paoletti P, Sheng M, Zhou Q, Hanson JE. Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. Neuron. PMID 26875626 DOI: 10.1016/J.Neuron.2016.01.016 |
0.544 |
|
| 2015 |
Bouvier G, Bidoret C, Casado M, Paoletti P. Presynaptic NMDA receptors: roles and rules. Neuroscience. PMID 26597763 DOI: 10.1016/J.Neuroscience.2015.10.033 |
0.639 |
|
| 2015 |
Zhu S, Paoletti P. Allosteric modulators of NMDA receptors: multiple sites and mechanisms. Current Opinion in Pharmacology. 20: 14-23. PMID 25462287 DOI: 10.1016/J.Coph.2014.10.009 |
0.547 |
|
| 2015 |
Paoletti P. NMDA Receptors as Dynamic Allosteric Machines Biophysical Journal. 108: 336a. DOI: 10.1016/J.Bpj.2014.11.1832 |
0.57 |
|
| 2014 |
Stroebel D, Carvalho S, Grand T, Zhu S, Paoletti P. Controlling NMDA receptor subunit composition using ectopic retention signals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16630-6. PMID 25505316 DOI: 10.1523/Jneurosci.2736-14.2014 |
0.57 |
|
| 2014 |
Stroebel D, Paoletti P. Neuroscience: A structure to remember. Nature. 511: 162-3. PMID 25008517 DOI: 10.1038/511162A |
0.565 |
|
| 2014 |
Vergnano AM, Rebola N, Savtchenko LP, Pinheiro PS, Casado M, Kieffer BL, Rusakov DA, Mulle C, Paoletti P. Zinc dynamics and action at excitatory synapses. Neuron. 82: 1101-14. PMID 24908489 DOI: 10.1016/J.Neuron.2014.04.034 |
0.553 |
|
| 2014 |
Zhu S, Riou M, Yao CA, Carvalho S, Rodriguez PC, Bensaude O, Paoletti P, Ye S. Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces. Proceedings of the National Academy of Sciences of the United States of America. 111: 6081-6. PMID 24715733 DOI: 10.1073/Pnas.1318808111 |
0.544 |
|
| 2013 |
Paoletti P, Bellone C, Zhou Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nature Reviews. Neuroscience. 14: 383-400. PMID 23686171 DOI: 10.1038/Nrn3504 |
0.576 |
|
| 2013 |
Zhu S, Stroebel D, Yao CA, Taly A, Paoletti P. Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain. Nature Structural & Molecular Biology. 20: 477-85. PMID 23454977 DOI: 10.1038/Nsmb.2522 |
0.519 |
|
| 2013 |
Ye S, Riou M, Carvalho S, Paoletti P. Expanding the genetic code in Xenopus laevis oocytes. Chembiochem : a European Journal of Chemical Biology. 14: 230-5. PMID 23292655 DOI: 10.1002/Cbic.201200515 |
0.434 |
|
| 2013 |
Suzuki Y, Goetze TA, Stroebel D, Balasuriya D, Yoshimura SH, Henderson RM, Paoletti P, Takeyasu K, Edwardson JM. Visualization of structural changes accompanying activation of N-methyl-D-aspartate (NMDA) receptors using fast-scan atomic force microscopy imaging. The Journal of Biological Chemistry. 288: 778-84. PMID 23223336 DOI: 10.1074/Jbc.M112.422311 |
0.542 |
|
| 2012 |
Boulin T, Rapti G, Briseño-Roa L, Stigloher C, Richmond JE, Paoletti P, Bessereau JL. Positive modulation of a Cys-loop acetylcholine receptor by an auxiliary transmembrane subunit. Nature Neuroscience. 15: 1374-81. PMID 22922783 DOI: 10.1038/Nn.3197 |
0.515 |
|
| 2012 |
Riou M, Stroebel D, Edwardson JM, Paoletti P. An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors. Plos One. 7: e35134. PMID 22493736 DOI: 10.1371/Journal.Pone.0035134 |
0.567 |
|
| 2012 |
Smart TG, Paoletti P. Synaptic neurotransmitter-gated receptors. Cold Spring Harbor Perspectives in Biology. 4. PMID 22233560 DOI: 10.1101/Cshperspect.A009662 |
0.712 |
|
| 2012 |
Marchand P, Becerril-Ortega J, Mony L, Bouteiller C, Paoletti P, Nicole O, Barré L, Buisson A, Perrio C. Confocal microscopy imaging of NR2B-containing NMDA receptors based on fluorescent ifenprodil-like conjugates. Bioconjugate Chemistry. 23: 21-6. PMID 22148315 DOI: 10.1021/Bc100571G |
0.421 |
|
| 2011 |
Sensi SL, Paoletti P, Koh JY, Aizenman E, Bush AI, Hershfinkel M. The neurophysiology and pathology of brain zinc. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16076-85. PMID 22072659 DOI: 10.1523/Jneurosci.3454-11.2011 |
0.302 |
|
| 2011 |
Nozaki C, Vergnano AM, Filliol D, Ouagazzal AM, Le Goff A, Carvalho S, Reiss D, Gaveriaux-Ruff C, Neyton J, Paoletti P, Kieffer BL. Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit. Nature Neuroscience. 14: 1017-22. PMID 21725314 DOI: 10.1038/Nn.2844 |
0.406 |
|
| 2011 |
Mony L, Zhu S, Carvalho S, Paoletti P. Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines. The Embo Journal. 30: 3134-46. PMID 21685875 DOI: 10.1038/Emboj.2011.203 |
0.57 |
|
| 2011 |
Paoletti P. Molecular basis of NMDA receptor functional diversity. The European Journal of Neuroscience. 33: 1351-65. PMID 21395862 DOI: 10.1111/J.1460-9568.2011.07628.X |
0.556 |
|
| 2011 |
Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Díaz-Hernández M, et al. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain : a Journal of Neurology. 134: 119-36. PMID 20929960 DOI: 10.1093/Brain/Awq278 |
0.332 |
|
| 2011 |
Stroebel D, Carvalho S, Paoletti P. Functional evidence for a twisted conformation of the NMDA receptor GluN2A subunit N-terminal domain. Neuropharmacology. 60: 151-8. PMID 20621105 DOI: 10.1016/J.Neuropharm.2010.07.003 |
0.58 |
|
| 2010 |
Mony L, Triballeau N, Paoletti P, Acher FC, Bertrand HO. Identification of a novel NR2B-selective NMDA receptor antagonist using a virtual screening approach. Bioorganic & Medicinal Chemistry Letters. 20: 5552-8. PMID 20692832 DOI: 10.1016/J.Bmcl.2010.07.043 |
0.399 |
|
| 2009 |
Mony L, Kew JN, Gunthorpe MJ, Paoletti P. Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential. British Journal of Pharmacology. 157: 1301-17. PMID 19594762 DOI: 10.1111/J.1476-5381.2009.00304.X |
0.566 |
|
| 2009 |
Gielen M, Siegler Retchless B, Mony L, Johnson JW, Paoletti P. Mechanism of differential control of NMDA receptor activity by NR2 subunits. Nature. 459: 703-7. PMID 19404260 DOI: 10.1038/Nature07993 |
0.756 |
|
| 2009 |
Mony L, Krzaczkowski L, Leonetti M, Le Goff A, Alarcon K, Neyton J, Bertrand HO, Acher F, Paoletti P. Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors. Molecular Pharmacology. 75: 60-74. PMID 18923063 DOI: 10.1124/Mol.108.050971 |
0.529 |
|
| 2009 |
Paoletti P, Vergnano AM, Barbour B, Casado M. Zinc at glutamatergic synapses. Neuroscience. 158: 126-36. PMID 18353558 DOI: 10.1016/J.Neuroscience.2008.01.061 |
0.624 |
|
| 2008 |
Boulin T, Gielen M, Richmond JE, Williams DC, Paoletti P, Bessereau JL. Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 105: 18590-5. PMID 19020092 DOI: 10.1073/Pnas.0806933105 |
0.629 |
|
| 2008 |
Alarcon K, Martz A, Mony L, Neyton J, Paoletti P, Goeldner M, Foucaud B. Reactive derivatives for affinity labeling in the ifenprodil site of NMDA receptors. Bioorganic & Medicinal Chemistry Letters. 18: 2765-70. PMID 18434149 DOI: 10.1016/J.Bmcl.2008.04.019 |
0.459 |
|
| 2008 |
Gielen M, Le Goff A, Stroebel D, Johnson JW, Neyton J, Paoletti P. Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition. Neuron. 57: 80-93. PMID 18184566 DOI: 10.1016/J.Neuron.2007.11.021 |
0.751 |
|
| 2007 |
Paoletti P, Neyton J. NMDA receptor subunits: function and pharmacology. Current Opinion in Pharmacology. 7: 39-47. PMID 17088105 DOI: 10.1016/J.Coph.2006.08.011 |
0.558 |
|
| 2006 |
Kay AR, Neyton J, Paoletti P. A startling role for synaptic zinc. Neuron. 52: 572-4. PMID 17114041 DOI: 10.1016/J.Neuron.2006.11.007 |
0.368 |
|
| 2006 |
Neyton J, Paoletti P. Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1331-3. PMID 16452656 DOI: 10.1523/Jneurosci.5242-05.2006 |
0.542 |
|
| 2005 |
Hatton CJ, Paoletti P. Modulation of triheteromeric NMDA receptors by N-terminal domain ligands. Neuron. 46: 261-74. PMID 15848804 DOI: 10.1016/J.Neuron.2005.03.005 |
0.556 |
|
| 2005 |
Rachline J, Perin-Dureau F, Le Goff A, Neyton J, Paoletti P. The micromolar zinc-binding domain on the NMDA receptor subunit NR2B. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 308-17. PMID 15647474 DOI: 10.1523/Jneurosci.3967-04.2005 |
0.539 |
|
| 2003 |
Malherbe P, Mutel V, Broger C, Perin-Dureau F, Kemp JA, Neyton J, Paoletti P, Kew JN. Identification of critical residues in the amino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket. The Journal of Pharmacology and Experimental Therapeutics. 307: 897-905. PMID 14534359 DOI: 10.1124/Jpet.103.056291 |
0.464 |
|
| 2002 |
Perin-Dureau F, Rachline J, Neyton J, Paoletti P. Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5955-65. PMID 12122058 DOI: 10.1523/Jneurosci.22-14-05955.2002 |
0.562 |
|
| 2000 |
Paoletti P, Perin-Dureau F, Fayyazuddin A, Le Goff A, Callebaut I, Neyton J. Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit. Neuron. 28: 911-25. PMID 11163276 DOI: 10.1016/S0896-6273(00)00163-X |
0.478 |
|
| 1999 |
Paoletti P, Young EC, Siegelbaum SA. C-Linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gating. The Journal of General Physiology. 113: 17-34. PMID 9874685 DOI: 10.1085/Jgp.113.1.17 |
0.706 |
|
| 1998 |
Liu DT, Tibbs GR, Paoletti P, Siegelbaum SA. Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers. Neuron. 21: 235-48. PMID 9697867 DOI: 10.1016/S0896-6273(00)80530-9 |
0.695 |
|
| 1997 |
Paoletti P, Ascher P, Neyton J. High-affinity zinc inhibition of NMDA NR1-NR2A receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5711-25. PMID 9221770 |
0.73 |
|
| 1997 |
Paoletti P, Ascher P, Neyton J. High-Affinity Zinc Inhibition of NMDA NR1–NR2A Receptors The Journal of Neuroscience. 17: 5711-5725. DOI: 10.1523/Jneurosci.17-15-05711.1997 |
0.74 |
|
| 1995 |
Paoletti P, Neyton J, Ascher P. Glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg2+. Neuron. 15: 1109-20. PMID 7576654 DOI: 10.1016/0896-6273(95)90099-3 |
0.733 |
|
| 1994 |
Paoletti P, Ascher P. Mechanosensitivity of NMDA receptors in cultured mouse central neurons. Neuron. 13: 645-55. PMID 7917295 DOI: 10.1016/0896-6273(94)90032-9 |
0.706 |
|
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