Pierre Paoletti - Publications

Neurobiology École normale supérieure Paris, Paris, Île-de-France, France 

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Paoletti P, Trautmann A, Marty A. Philippe Ascher (1936-2022). Neuron. 110: 3864-3865. PMID 36480941 DOI: 10.1016/j.neuron.2022.10.038  0.319
2022 Paoletti P, Trautmann A, Marty A. Remembering a giant of neuroscience. Nature. 611: 236. PMID 36347959 DOI: 10.1038/d41586-022-03584-w  0.322
2022 Sikora J, Di Bisceglie Caballero S, Reiss D, Kieffer BL, Paoletti P, Jacob PY, Ouagazzal AM. Zn inhibits spatial memory and hippocampal place cell representation through high-affinity binding to the NMDA receptor GluN2A subunit. Iscience. 25: 105355. PMID 36325055 DOI: 10.1016/j.isci.2022.105355  0.36
2022 Bossi S, Dhanasobhon D, Ellis-Davies GCR, Frontera J, de Brito Van Velze M, Lourenço J, Murillo A, Luján R, Casado M, Perez-Otaño I, Bacci A, Popa D, Paoletti P, Rebola N. GluN3A excitatory glycine receptors control adult cortical and amygdalar circuits. Neuron. PMID 35700736 DOI: 10.1016/j.neuron.2022.05.016  0.572
2022 Morabito A, Zerlaut Y, Serraz B, Sala R, Paoletti P, Rebola N. Activity-dependent modulation of NMDA receptors by endogenous zinc shapes dendritic function in cortical neurons. Cell Reports. 38: 110415. PMID 35196488 DOI: 10.1016/j.celrep.2022.110415  0.313
2021 Thapaliya ER, Mony L, Sanchez R, Serraz B, Paoletti P, Ellis-Davies GCR. Photochemical control of drug efficacy - a comparison of uncaging and photoswitching ifenprodil on NMDA receptors. Chemphotochem. 5: 445-454. PMID 36540756 DOI: 10.1002/cptc.202000240  0.393
2021 Tian M, Stroebel D, Piot L, David M, Ye S, Paoletti P. GluN2A and GluN2B NMDA receptors use distinct allosteric routes. Nature Communications. 12: 4709. PMID 34354080 DOI: 10.1038/s41467-021-25058-9  0.505
2021 Geoffroy C, Paoletti P, Mony L. Positive allosteric modulation of NMDA receptors: mechanisms, physiological impact and therapeutic potential. The Journal of Physiology. PMID 34339523 DOI: 10.1113/JP280875  0.412
2021 Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S. Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors. Neuron. PMID 34186027 DOI: 10.1016/j.neuron.2021.05.031  0.498
2021 Stroebel D, Mony L, Paoletti P. Glycine agonism in ionotropic glutamate receptors. Neuropharmacology. 193: 108631. PMID 34058193 DOI: 10.1016/j.neuropharm.2021.108631  0.494
2020 Stroebel D, Paoletti P. Architecture and function of NMDA receptors: an evolutionary perspective. The Journal of Physiology. PMID 32786006 DOI: 10.1113/Jp279028  0.523
2020 Shin W, Kim K, Serraz B, Cho YS, Kim D, Kang M, Lee EJ, Lee H, Bae YC, Paoletti P, Kim E. Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice. Plos Biology. 18: e3000717. PMID 32353004 DOI: 10.1371/Journal.Pbio.3000717  0.33
2020 Mony L, Paoletti P. Photocontrol of Metabotropic Glutamate Receptors: When One Agonist Is Not Enough, Make It Two. Neuron. 105: 395-397. PMID 32027826 DOI: 10.1016/J.Neuron.2020.01.013  0.5
2019 Sikora J, Kieffer BL, Paoletti P, Ouagazzal AM. Synaptic zinc contributes to motor and cognitive deficits in 6-hydroxydopamine mouse models of Parkinson's disease. Neurobiology of Disease. 134: 104681. PMID 31759136 DOI: 10.1016/J.Nbd.2019.104681  0.321
2019 Otsu Y, Darcq E, Pietrajtis K, Mátyás F, Schwartz E, Bessaih T, Abi Gerges S, Rousseau CV, Grand T, Dieudonné S, Paoletti P, Acsády L, Agulhon C, Kieffer BL, Diana MA. Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula. Science (New York, N.Y.). 366: 250-254. PMID 31601771 DOI: 10.1126/Science.Aax1522  0.762
2019 Paoletti P, Ellis-Davies GCR, Mourot A. Optical control of neuronal ion channels and receptors. Nature Reviews. Neuroscience. PMID 31289380 DOI: 10.1038/S41583-019-0197-2  0.422
2018 Yao L, Grand T, Hanson JE, Paoletti P, Zhou Q. Author Correction: Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity. Nature Communications. 9: 4887. PMID 30442888 DOI: 10.1038/S41467-018-07441-1  0.45
2018 Grand T, Abi Gerges S, David M, Diana MA, Paoletti P. Unmasking GluN1/GluN3A excitatory glycine NMDA receptors. Nature Communications. 9: 4769. PMID 30425244 DOI: 10.1038/S41467-018-07236-4  0.58
2018 Esmenjaud JB, Stroebel D, Chan K, Grand T, David M, Wollmuth LP, Taly A, Paoletti P. An inter-dimer allosteric switch controls NMDA receptor activity. The Embo Journal. PMID 30396997 DOI: 10.15252/Embj.201899894  0.528
2018 Yao L, Grand T, Hanson J, Paoletti P, Zhou Q. Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity. Nature Communications. 9: 4000. PMID 30275542 DOI: 10.1038/S41467-018-06512-7  0.422
2018 Stroebel D, Casado M, Paoletti P. Triheteromeric NMDA receptors: from structure to synaptic physiology. Current Opinion in Physiology. 2: 1-12. PMID 29682629 DOI: 10.1016/J.Cophys.2017.12.004  0.644
2018 Klippenstein V, Mony L, Paoletti P. Probing Ion Channel Structure and Function Using Light-Sensitive Amino Acids. Trends in Biochemical Sciences. PMID 29650383 DOI: 10.1016/J.Tibs.2018.02.012  0.321
2017 Ferreira JS, Papouin T, Ladépêche L, Yao A, Langlais VC, Bouchet D, Dulong J, Mothet JP, Sacchi S, Pollegioni L, Paoletti P, Oliet SHR, Groc L. Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses. Elife. 6. PMID 28598327 DOI: 10.7554/Elife.25492  0.52
2017 Klippenstein V, Hoppmann C, Ye S, Wang L, Paoletti P. Optocontrol of glutamate receptor activity by single side-chain photoisomerization. Elife. 6. PMID 28534738 DOI: 10.7554/Elife.25808  0.46
2017 Klippenstein V, Hoppmann C, Ye S, Wang L, Paoletti P. Author response: Optocontrol of glutamate receptor activity by single side-chain photoisomerization Elife. DOI: 10.7554/Elife.25808.028  0.457
2017 Ferreira JS, Papouin T, Ladépêche L, Yao A, Langlais VC, Bouchet D, Dulong J, Mothet J, Sacchi S, Pollegioni L, Paoletti P, Oliet SHR, Groc L. Author response: Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses Elife. DOI: 10.7554/Elife.25492.016  0.509
2016 Serraz B, Grand T, Paoletti P. Altered zinc sensitivity of NMDA receptors harboring clinically-relevant mutations. Neuropharmacology. PMID 27288002 DOI: 10.1016/J.Neuropharm.2016.06.008  0.481
2016 Stroebel D, Buhl DL, Knafels JD, Chanda PK, Green M, Sciabola S, Mony L, Paoletti P, Pandit J. A novel binding mode reveals two distinct classes of NMDA receptor GluN2B-selective antagonists. Molecular Pharmacology. PMID 26912815 DOI: 10.1124/Mol.115.103036  0.511
2016 Hackos DH, Lupardus PJ, Grand T, Chen Y, Wang TM, Reynen P, Gustafson A, Wallweber HJ, Volgraf M, Sellers BD, Schwarz JB, Paoletti P, Sheng M, Zhou Q, Hanson JE. Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. Neuron. PMID 26875626 DOI: 10.1016/J.Neuron.2016.01.016  0.544
2015 Bouvier G, Bidoret C, Casado M, Paoletti P. Presynaptic NMDA receptors: roles and rules. Neuroscience. PMID 26597763 DOI: 10.1016/J.Neuroscience.2015.10.033  0.639
2015 Zhu S, Paoletti P. Allosteric modulators of NMDA receptors: multiple sites and mechanisms. Current Opinion in Pharmacology. 20: 14-23. PMID 25462287 DOI: 10.1016/J.Coph.2014.10.009  0.547
2015 Paoletti P. NMDA Receptors as Dynamic Allosteric Machines Biophysical Journal. 108: 336a. DOI: 10.1016/J.Bpj.2014.11.1832  0.57
2014 Stroebel D, Carvalho S, Grand T, Zhu S, Paoletti P. Controlling NMDA receptor subunit composition using ectopic retention signals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16630-6. PMID 25505316 DOI: 10.1523/Jneurosci.2736-14.2014  0.57
2014 Stroebel D, Paoletti P. Neuroscience: A structure to remember. Nature. 511: 162-3. PMID 25008517 DOI: 10.1038/511162A  0.565
2014 Vergnano AM, Rebola N, Savtchenko LP, Pinheiro PS, Casado M, Kieffer BL, Rusakov DA, Mulle C, Paoletti P. Zinc dynamics and action at excitatory synapses. Neuron. 82: 1101-14. PMID 24908489 DOI: 10.1016/J.Neuron.2014.04.034  0.553
2014 Zhu S, Riou M, Yao CA, Carvalho S, Rodriguez PC, Bensaude O, Paoletti P, Ye S. Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces. Proceedings of the National Academy of Sciences of the United States of America. 111: 6081-6. PMID 24715733 DOI: 10.1073/Pnas.1318808111  0.544
2013 Paoletti P, Bellone C, Zhou Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nature Reviews. Neuroscience. 14: 383-400. PMID 23686171 DOI: 10.1038/Nrn3504  0.576
2013 Zhu S, Stroebel D, Yao CA, Taly A, Paoletti P. Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain. Nature Structural & Molecular Biology. 20: 477-85. PMID 23454977 DOI: 10.1038/Nsmb.2522  0.519
2013 Ye S, Riou M, Carvalho S, Paoletti P. Expanding the genetic code in Xenopus laevis oocytes. Chembiochem : a European Journal of Chemical Biology. 14: 230-5. PMID 23292655 DOI: 10.1002/Cbic.201200515  0.434
2013 Suzuki Y, Goetze TA, Stroebel D, Balasuriya D, Yoshimura SH, Henderson RM, Paoletti P, Takeyasu K, Edwardson JM. Visualization of structural changes accompanying activation of N-methyl-D-aspartate (NMDA) receptors using fast-scan atomic force microscopy imaging. The Journal of Biological Chemistry. 288: 778-84. PMID 23223336 DOI: 10.1074/Jbc.M112.422311  0.542
2012 Boulin T, Rapti G, Briseño-Roa L, Stigloher C, Richmond JE, Paoletti P, Bessereau JL. Positive modulation of a Cys-loop acetylcholine receptor by an auxiliary transmembrane subunit. Nature Neuroscience. 15: 1374-81. PMID 22922783 DOI: 10.1038/Nn.3197  0.515
2012 Riou M, Stroebel D, Edwardson JM, Paoletti P. An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors. Plos One. 7: e35134. PMID 22493736 DOI: 10.1371/Journal.Pone.0035134  0.567
2012 Smart TG, Paoletti P. Synaptic neurotransmitter-gated receptors. Cold Spring Harbor Perspectives in Biology. 4. PMID 22233560 DOI: 10.1101/Cshperspect.A009662  0.712
2012 Marchand P, Becerril-Ortega J, Mony L, Bouteiller C, Paoletti P, Nicole O, Barré L, Buisson A, Perrio C. Confocal microscopy imaging of NR2B-containing NMDA receptors based on fluorescent ifenprodil-like conjugates. Bioconjugate Chemistry. 23: 21-6. PMID 22148315 DOI: 10.1021/Bc100571G  0.421
2011 Sensi SL, Paoletti P, Koh JY, Aizenman E, Bush AI, Hershfinkel M. The neurophysiology and pathology of brain zinc. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16076-85. PMID 22072659 DOI: 10.1523/Jneurosci.3454-11.2011  0.302
2011 Nozaki C, Vergnano AM, Filliol D, Ouagazzal AM, Le Goff A, Carvalho S, Reiss D, Gaveriaux-Ruff C, Neyton J, Paoletti P, Kieffer BL. Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit. Nature Neuroscience. 14: 1017-22. PMID 21725314 DOI: 10.1038/Nn.2844  0.406
2011 Mony L, Zhu S, Carvalho S, Paoletti P. Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines. The Embo Journal. 30: 3134-46. PMID 21685875 DOI: 10.1038/Emboj.2011.203  0.57
2011 Paoletti P. Molecular basis of NMDA receptor functional diversity. The European Journal of Neuroscience. 33: 1351-65. PMID 21395862 DOI: 10.1111/J.1460-9568.2011.07628.X  0.556
2011 Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Díaz-Hernández M, et al. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain : a Journal of Neurology. 134: 119-36. PMID 20929960 DOI: 10.1093/Brain/Awq278  0.332
2011 Stroebel D, Carvalho S, Paoletti P. Functional evidence for a twisted conformation of the NMDA receptor GluN2A subunit N-terminal domain. Neuropharmacology. 60: 151-8. PMID 20621105 DOI: 10.1016/J.Neuropharm.2010.07.003  0.58
2010 Mony L, Triballeau N, Paoletti P, Acher FC, Bertrand HO. Identification of a novel NR2B-selective NMDA receptor antagonist using a virtual screening approach. Bioorganic & Medicinal Chemistry Letters. 20: 5552-8. PMID 20692832 DOI: 10.1016/J.Bmcl.2010.07.043  0.399
2009 Mony L, Kew JN, Gunthorpe MJ, Paoletti P. Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential. British Journal of Pharmacology. 157: 1301-17. PMID 19594762 DOI: 10.1111/J.1476-5381.2009.00304.X  0.566
2009 Gielen M, Siegler Retchless B, Mony L, Johnson JW, Paoletti P. Mechanism of differential control of NMDA receptor activity by NR2 subunits. Nature. 459: 703-7. PMID 19404260 DOI: 10.1038/Nature07993  0.756
2009 Mony L, Krzaczkowski L, Leonetti M, Le Goff A, Alarcon K, Neyton J, Bertrand HO, Acher F, Paoletti P. Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors. Molecular Pharmacology. 75: 60-74. PMID 18923063 DOI: 10.1124/Mol.108.050971  0.529
2009 Paoletti P, Vergnano AM, Barbour B, Casado M. Zinc at glutamatergic synapses. Neuroscience. 158: 126-36. PMID 18353558 DOI: 10.1016/J.Neuroscience.2008.01.061  0.624
2008 Boulin T, Gielen M, Richmond JE, Williams DC, Paoletti P, Bessereau JL. Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 105: 18590-5. PMID 19020092 DOI: 10.1073/Pnas.0806933105  0.629
2008 Alarcon K, Martz A, Mony L, Neyton J, Paoletti P, Goeldner M, Foucaud B. Reactive derivatives for affinity labeling in the ifenprodil site of NMDA receptors. Bioorganic & Medicinal Chemistry Letters. 18: 2765-70. PMID 18434149 DOI: 10.1016/J.Bmcl.2008.04.019  0.459
2008 Gielen M, Le Goff A, Stroebel D, Johnson JW, Neyton J, Paoletti P. Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition. Neuron. 57: 80-93. PMID 18184566 DOI: 10.1016/J.Neuron.2007.11.021  0.751
2007 Paoletti P, Neyton J. NMDA receptor subunits: function and pharmacology. Current Opinion in Pharmacology. 7: 39-47. PMID 17088105 DOI: 10.1016/J.Coph.2006.08.011  0.558
2006 Kay AR, Neyton J, Paoletti P. A startling role for synaptic zinc. Neuron. 52: 572-4. PMID 17114041 DOI: 10.1016/J.Neuron.2006.11.007  0.368
2006 Neyton J, Paoletti P. Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1331-3. PMID 16452656 DOI: 10.1523/Jneurosci.5242-05.2006  0.542
2005 Hatton CJ, Paoletti P. Modulation of triheteromeric NMDA receptors by N-terminal domain ligands. Neuron. 46: 261-74. PMID 15848804 DOI: 10.1016/J.Neuron.2005.03.005  0.556
2005 Rachline J, Perin-Dureau F, Le Goff A, Neyton J, Paoletti P. The micromolar zinc-binding domain on the NMDA receptor subunit NR2B. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 308-17. PMID 15647474 DOI: 10.1523/Jneurosci.3967-04.2005  0.539
2003 Malherbe P, Mutel V, Broger C, Perin-Dureau F, Kemp JA, Neyton J, Paoletti P, Kew JN. Identification of critical residues in the amino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket. The Journal of Pharmacology and Experimental Therapeutics. 307: 897-905. PMID 14534359 DOI: 10.1124/Jpet.103.056291  0.464
2002 Perin-Dureau F, Rachline J, Neyton J, Paoletti P. Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5955-65. PMID 12122058 DOI: 10.1523/Jneurosci.22-14-05955.2002  0.562
2000 Paoletti P, Perin-Dureau F, Fayyazuddin A, Le Goff A, Callebaut I, Neyton J. Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit. Neuron. 28: 911-25. PMID 11163276 DOI: 10.1016/S0896-6273(00)00163-X  0.478
1999 Paoletti P, Young EC, Siegelbaum SA. C-Linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gating. The Journal of General Physiology. 113: 17-34. PMID 9874685 DOI: 10.1085/Jgp.113.1.17  0.706
1998 Liu DT, Tibbs GR, Paoletti P, Siegelbaum SA. Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers. Neuron. 21: 235-48. PMID 9697867 DOI: 10.1016/S0896-6273(00)80530-9  0.695
1997 Paoletti P, Ascher P, Neyton J. High-affinity zinc inhibition of NMDA NR1-NR2A receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5711-25. PMID 9221770  0.73
1997 Paoletti P, Ascher P, Neyton J. High-Affinity Zinc Inhibition of NMDA NR1–NR2A Receptors The Journal of Neuroscience. 17: 5711-5725. DOI: 10.1523/Jneurosci.17-15-05711.1997  0.74
1995 Paoletti P, Neyton J, Ascher P. Glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg2+. Neuron. 15: 1109-20. PMID 7576654 DOI: 10.1016/0896-6273(95)90099-3  0.733
1994 Paoletti P, Ascher P. Mechanosensitivity of NMDA receptors in cultured mouse central neurons. Neuron. 13: 645-55. PMID 7917295 DOI: 10.1016/0896-6273(94)90032-9  0.706
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