Darrick T. Balu, Ph.D. - Publications

Psychiatry Harvard University, Cambridge, MA, United States 

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Coyle JT, Ruzicka WB, Balu DT. Fifty Years of Research on Schizophrenia: The Ascendance of the Glutamatergic Synapse. The American Journal of Psychiatry. 177: 1119-1128. PMID 33256439 DOI: 10.1176/appi.ajp.2020.20101481  0.4
2020 Takagi S, Balu DT, Coyle JT. Factors regulating serine racemase and D-amino acid oxidase expression in the mouse striatum. Brain Research. 147202. PMID 33171153 DOI: 10.1016/j.brainres.2020.147202  0.4
2020 Wong JM, Folorunso OO, Barragan EV, Berciu C, Harvey TL, Coyle JT, Balu DT, Gray JA. Postsynaptic serine racemase regulates NMDA receptor function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33158959 DOI: 10.1523/JNEUROSCI.1525-20.2020  0.4
2020 Takagi S, Puhl MD, Anderson T, Balu DT, Coyle JT. Serine Racemase Expression by Striatal Neurons. Cellular and Molecular Neurobiology. PMID 32445040 DOI: 10.1007/s10571-020-00880-9  0.4
2020 Coyle JT, Balu D, Wolosker H. D-Serine, the Shape-Shifting NMDA Receptor Co-agonist. Neurochemical Research. PMID 32189130 DOI: 10.1007/s11064-020-03014-1  0.4
2019 Balu DT, Pantazopoulos H, Huang CCY, Muszynski K, Harvey TL, Uno Y, Rorabaugh JM, Galloway CR, Botz-Zapp C, Berretta S, Weinshenker D, Coyle JT. Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease. Neurobiology of Disease. 104511. PMID 31212068 DOI: 10.1016/j.nbd.2019.104511  0.4
2018 Konopaske GT, Balu DT, Presti KT, Chan G, Benes FM, Coyle JT. Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia. Schizophrenia Research. PMID 29759351 DOI: 10.1016/j.schres.2018.04.042  0.4
2018 Coyle JT, Balu DT. The Role of Serine Racemase in the Pathophysiology of Brain Disorders. Advances in Pharmacology (San Diego, Calif.). 82: 35-56. PMID 29413527 DOI: 10.1016/bs.apha.2017.10.002  0.4
2018 Li S, Uno Y, Rudolph U, Cobb J, Liu J, Anderson T, Levy D, Balu DT, Coyle JT. Astrocytes in Primary Cultures Express Serine Racemase, Synthesize D-Serine and Acquire A1 Reactive Astrocyte Features. Biochemical Pharmacology. PMID 29305854 DOI: 10.1016/j.bcp.2017.12.023  0.4
2017 Balu DT, Coyle JT. Altered CREB Binding to Activity-Dependent Genes in Serine Racemase Deficient Mice, a Mouse Model of Schizophrenia. Acs Chemical Neuroscience. PMID 29172439 DOI: 10.1021/acschemneuro.7b00404  0.4
2017 Balu DT, Presti KT, Huang CCY, Muszynski K, Radzishevsky I, Wolosker H, Guffanti G, Ressler KJ, Coyle JT. Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning. Biological Psychiatry. PMID 29025687 DOI: 10.1016/j.biopsych.2017.08.012  0.4
2017 Wolosker H, Balu DT, Coyle JT. Astroglial Versus Neuronal D-Serine: Check Your Controls! Trends in Neurosciences. PMID 28756007 DOI: 10.1016/j.tins.2017.06.010  0.4
2017 Perez EJ, Tapanes SA, Loris ZB, Balu DT, Sick TJ, Coyle JT, Liebl DJ. Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury. The Journal of Clinical Investigation. PMID 28714867 DOI: 10.1172/JCI92300  0.4
2016 Wolosker H, Balu DT, Coyle JT. The Rise and Fall of the d-Serine-Mediated Gliotransmission Hypothesis. Trends in Neurosciences. PMID 27742076 DOI: 10.1016/j.tins.2016.09.007  0.4
2016 Coyle JT, Balu DT, Puhl MD, Konopaske GT. History of the Concept of Disconnectivity in Schizophrenia. Harvard Review of Psychiatry. 24: 80-6. PMID 26954593 DOI: 10.1097/HRP.0000000000000102  0.4
2016 Balu DT, Li Y, Takagi S, Presti KT, Ramikie TS, Rook JM, Jones CK, Lindsley CW, Conn PJ, Bolshakov VY, Coyle JT. An mGlu5 Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26741285 DOI: 10.1038/npp.2016.2  1
2016 Balu D, Ouyang J, Parakhia RA, Pitake S, Ochs RS. Ca2+ effects on glucose transport and fatty acid oxidation in L6 skeletal muscle cell cultures Biochemistry and Biophysics Reports. 5: 365-373. DOI: 10.1016/j.bbrep.2016.01.007  1
2015 Ishiwata S, Balu DT, Umino A, Coyle JT, Nishikawa T. [JSNP Excellent Presentation Award for CINP2014]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 35: 53-4. PMID 26027070  0.4
2015 Ishiwata S, Umino A, Balu DT, Coyle JT, Nishikawa T. Neuronal serine racemase regulates extracellular D-serine levels in the adult mouse hippocampus. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 25782690 DOI: 10.1007/s00702-015-1388-2  1
2015 Takagi S, Balu DT, Coyle JT. Subchronic pharmacological and chronic genetic NMDA receptor hypofunction differentially regulate the Akt signaling pathway and Arc expression in juvenile and adult mice. Schizophrenia Research. 162: 216-21. PMID 25592804 DOI: 10.1016/j.schres.2014.12.034  1
2015 Balu DT, Coyle JT. The NMDA receptor 'glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond. Current Opinion in Pharmacology. 20: 109-15. PMID 25540902 DOI: 10.1016/j.coph.2014.12.004  1
2014 Balu DT, Coyle JT. Chronic D-serine reverses arc expression and partially rescues dendritic abnormalities in a mouse model of NMDA receptor hypofunction. Neurochemistry International. 75: 76-8. PMID 24915645 DOI: 10.1016/j.neuint.2014.05.015  1
2014 Balu DT, Takagi S, Puhl MD, Benneyworth MA, Coyle JT. D-serine and serine racemase are localized to neurons in the adult mouse and human forebrain. Cellular and Molecular Neurobiology. 34: 419-35. PMID 24436034 DOI: 10.1007/s10571-014-0027-z  1
2014 Santini MA, Balu DT, Puhl MD, Hill-Smith TE, Berg AR, Lucki I, Mikkelsen JD, Coyle JT. D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT(2A) receptor agonist DOI. Behavioural Brain Research. 259: 242-6. PMID 24269270 DOI: 10.1016/j.bbr.2013.11.022  1
2013 Balu DT, Li Y, Puhl MD, Benneyworth MA, Basu AC, Takagi S, Bolshakov VY, Coyle JT. Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction. Proceedings of the National Academy of Sciences of the United States of America. 110: E2400-9. PMID 23729812 DOI: 10.1073/pnas.1304308110  1
2013 Balu DT, Turner JR, Brookshire BR, Hill-Smith TE, Blendy JA, Lucki I. Brain monoamines and antidepressant-like responses in MRL/MpJ versus C57BL/6J mice. Neuropharmacology. 67: 503-10. PMID 23220293 DOI: 10.1016/j.neuropharm.2012.11.027  1
2012 Coyle JT, Basu A, Benneyworth M, Balu D, Konopaske G. Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications. Handbook of Experimental Pharmacology. 267-95. PMID 23027419 DOI: 10.1007/978-3-642-25758-2_10  1
2012 Balu DT, Coyle JT. Neuronal D-serine regulates dendritic architecture in the somatosensory cortex. Neuroscience Letters. 517: 77-81. PMID 22521586 DOI: 10.1016/j.neulet.2012.04.020  1
2012 Balu DT, Basu AC, Corradi JP, Cacace AM, Coyle JT. The NMDA receptor co-agonists, D-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex. Neurobiology of Disease. 45: 671-82. PMID 22024716 DOI: 10.1016/j.nbd.2011.10.006  1
2012 Ho N, Balu DT, Hilario MR, Blendy JA, Lucki I. Depressive phenotypes evoked by experimental diabetes are reversed by insulin. Physiology & Behavior. 105: 702-8. PMID 21945451 DOI: 10.1016/j.physbeh.2011.09.003  1
2012 Balu DT, Carlson GC, Talbot K, Kazi H, Hill-Smith TE, Easton RM, Birnbaum MJ, Lucki I. Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function. Hippocampus. 22: 230-40. PMID 21049487 DOI: 10.1002/hipo.20887  1
2012 Balu DT, Goff DC. Schizophrenia Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders. 80-106. DOI: 10.1017/CBO9780511980053.005  1
2011 Balu DT, Coyle JT. Glutamate receptor composition of the post-synaptic density is altered in genetic mouse models of NMDA receptor hypo- and hyperfunction. Brain Research. 1392: 1-7. PMID 21443867 DOI: 10.1016/j.brainres.2011.03.051  1
2011 DeVito LM, Balu DT, Kanter BR, Lykken C, Basu AC, Coyle JT, Eichenbaum H. Serine racemase deletion disrupts memory for order and alters cortical dendritic morphology. Genes, Brain, and Behavior. 10: 210-22. PMID 21029376 DOI: 10.1111/j.1601-183X.2010.00656.x  1
2011 Balu DT, Coyle JT. Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia. Neuroscience and Biobehavioral Reviews. 35: 848-70. PMID 20951727 DOI: 10.1016/j.neubiorev.2010.10.005  1
2010 Coyle JT, Balu D, Benneyworth M, Basu A, Roseman A. Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia. Dialogues in Clinical Neuroscience. 12: 359-82. PMID 20954431  1
2010 Balu DT. Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of acute and chronic antidepressant treatments. Experimental and Clinical Psychopharmacology. 18: 71-7. PMID 20158296 DOI: 10.1037/a0017295  1
2009 Balu DT, Hodes GE, Anderson BT, Lucki I. Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of chronic antidepressant treatments. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1764-73. PMID 19177066 DOI: 10.1038/npp.2008.234  1
2009 Balu DT, Hodes GE, Hill TE, Ho N, Rahman Z, Bender CN, Ring RH, Dwyer JM, Rosenzweig-Lipson S, Hughes ZA, Schechter LE, Lucki I. Flow cytometric analysis of BrdU incorporation as a high-throughput method for measuring adult neurogenesis in the mouse. Journal of Pharmacological and Toxicological Methods. 59: 100-7. PMID 19121403 DOI: 10.1016/j.vascn.2008.12.002  1
2009 Balu DT, Lucki I. Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology. Neuroscience and Biobehavioral Reviews. 33: 232-52. PMID 18786562 DOI: 10.1016/j.neubiorev.2008.08.007  1
2008 Balu DT, Hoshaw BA, Malberg JE, Rosenzweig-Lipson S, Schechter LE, Lucki I. Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments. Brain Research. 1211: 37-43. PMID 18433734 DOI: 10.1016/j.brainres.2008.03.023  1
2001 Ali SH, O'Donnell AL, Balu D, Pohl MB, Seyler MJ, Mohamed S, Mousa S, Dandona P. High levels of oestrogen receptor-alpha in tumorigenesis: inhibition of cell growth and angiogenic factors. Cell Proliferation. 34: 223-31. PMID 11529880 DOI: 10.1046/j.0960-7722.2001.00207.x  1
2000 Ali SH, O'Donnell AL, Balu D, Pohl MB, Seyler MJ, Mohamed S, Mousa S, Dandona P. Estrogen receptor-alpha in the inhibition of cancer growth and angiogenesis. Cancer Research. 60: 7094-8. PMID 11156416  1
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