Michael J. Detke - Publications

Affiliations: 
MedAvante, Hamilton Township, NJ, United States 
Area:
Drug development

10/123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Chappell JC, Eisenhofer G, Owens MJ, Haber H, Lachno DR, Dean RA, Knadler MP, Nemeroff CB, Mitchell MI, Detke MJ, Iyengar S, Pangallo B, Lobo ED. Effects of duloxetine on norepinephrine and serotonin transporter activity in healthy subjects. Journal of Clinical Psychopharmacology. 34: 9-16. PMID 24346757 DOI: 10.1097/JCP.0000000000000061  0.318
2008 Trivedi MH, Desaiah D, Ossanna MJ, Pritchett YL, Brannan SK, Detke MJ. Clinical evidence for serotonin and norepinephrine reuptake inhibition of duloxetine. International Clinical Psychopharmacology. 23: 161-9. PMID 18408530 DOI: 10.1097/YIC.0b013e3282f41d7e  0.373
2005 Bymaster FP, Lee TC, Knadler MP, Detke MJ, Iyengar S. The dual transporter inhibitor duloxetine: a review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression. Current Pharmaceutical Design. 11: 1475-93. PMID 15892657 DOI: 10.2174/1381612053764805  0.352
2002 Carlezon WA, Pliakas AM, Parow AM, Detke MJ, Cohen BM, Renshaw PF. Antidepressant-like effects of cytidine in the forced swim test in rats. Biological Psychiatry. 51: 882-9. PMID 12022961 DOI: 10.1016/S0006-3223(01)01344-0  0.408
2002 Chalon S, Bieck PR, Goldstein DJ, Detke MJ, Bymaster FP, Potter WZ, Demitrack MA. The tyramine pressor test may have limited sensitivity, especially in the presence of dual serotonin/norepinephrine uptake inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 698-9; author reply . PMID 11927196 DOI: 10.1016/S0893-133X(01)00409-2  0.334
1999 Page ME, Detke MJ, Dalvi A, Kirby LG, Lucki I. Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test. Psychopharmacology. 147: 162-7. PMID 10591883 DOI: 10.1007/S002130051156  0.576
1997 Detke MJ, Johnson J, Lucki I. Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression. Experimental and Clinical Psychopharmacology. 5: 107-12. PMID 9234045 DOI: 10.1037/1064-1297.5.2.107  0.648
1996 Detke MJ, Lucki I. Detection of serotonergic and noradrenergic antidepressants in the rat forced swimming test: the effects of water depth. Behavioural Brain Research. 73: 43-6. PMID 8788475 DOI: 10.1016/0166-4328(96)00067-8  0.678
1995 Detke MJ, Rickels M, Lucki I. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology. 121: 66-72. PMID 8539342 DOI: 10.1007/Bf02245592  0.704
1995 Detke MJ, Wieland S, Lucki I. Blockade of the antidepressant-like effects of 8-OH-DPAT, buspirone and desipramine in the rat forced swim test by 5HT1A receptor antagonists. Psychopharmacology. 119: 47-54. PMID 7675949 DOI: 10.1007/Bf02246053  0.591
Low-probability matches (unlikely to be authored by this person)
1991 Detke MJ. Extinction of sequential conditioned inhibition Animal Learning & Behavior. 19: 345-354. DOI: 10.3758/Bf03197895  0.289
2007 Thase ME, Pritchett YL, Ossanna MJ, Swindle RW, Xu J, Detke MJ. Efficacy of duloxetine and selective serotonin reuptake inhibitors: comparisons as assessed by remission rates in patients with major depressive disorder. Journal of Clinical Psychopharmacology. 27: 672-6. PMID 18004135 DOI: 10.1097/jcp.0b013e31815a4412  0.284
2010 Mallinckrodt CH, Detke MJ, Prucka WR, Ruberg SJ, Molenberghs G. Considerations for Comparing a Test Drug with Standard of Care in Phase 2 Clinical Trials of Central Nervous System Disorders Drug Information Journal. 44: 443-452. DOI: 10.1177/009286151004400408  0.275
2007 Mallinckrodt CH, Meyers AL, Prakash A, Faries DE, Detke MJ. Simple options for improving signal detection in antidepressant clinical trials. Psychopharmacology Bulletin. 40: 101-14. PMID 17514189  0.264
2002 Nemeroff CB, Schatzberg AF, Goldstein DJ, Detke MJ, Mallinckrodt C, Lu Y, Tran PV. Duloxetine for the treatment of major depressive disorder. Psychopharmacology Bulletin. 36: 106-32. PMID 12858150  0.261
2007 Mallinckrodt CH, Prakash A, Houston JP, Swindle R, Detke MJ, Fava M. Differential antidepressant symptom efficacy: placebo-controlled comparisons of duloxetine and SSRIs (fluoxetine, paroxetine, escitalopram). Neuropsychobiology. 56: 73-85. PMID 18037817 DOI: 10.1159/000111537  0.256
2005 Thase ME, Tran PV, Wiltse C, Pangallo BA, Mallinckrodt C, Detke MJ. Cardiovascular profile of duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine. Journal of Clinical Psychopharmacology. 25: 132-40. PMID 15738744 DOI: 10.1097/01.jcp.0000155815.44338.95  0.25
2002 Detke MJ, Lu Y, Goldstein DJ, McNamara RK, Demitrack MA. Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression. Journal of Psychiatric Research. 36: 383-90. PMID 12393307 DOI: 10.1016/S0022-3956(02)00060-2  0.243
2007 Hudson JI, Perahia DG, Gilaberte I, Wang F, Watkin JG, Detke MJ. Duloxetine in the treatment of major depressive disorder: an open-label study. Bmc Psychiatry. 7: 43. PMID 17725843 DOI: 10.1186/1471-244X-7-43  0.242
2006 Perahia DG, Gilaberte I, Wang F, Wiltse CG, Huckins SA, Clemens JW, Montgomery SA, Montejo AL, Detke MJ. Duloxetine in the prevention of relapse of major depressive disorder: double-blind placebo-controlled study. The British Journal of Psychiatry : the Journal of Mental Science. 188: 346-53. PMID 16582061 DOI: 10.1192/bjp.188.4.346  0.24
2003 Fishbain DA, Detke MJ. Analgesic effect of antidepressants [2] (multiple letters) Journal of Clinical Psychiatry. 64: 96-97. PMID 12590632  0.235
2003 Dunner DL, Goldstein DJ, Mallinckrodt C, Lu Y, Detke MJ. Duloxetine in treatment of anxiety symptoms associated with depression. Depression and Anxiety. 18: 53-61. PMID 12964171 DOI: 10.1002/da.10122  0.226
2005 Dunner DL, D'Souza DN, Kajdasz DK, Detke MJ, Russell JM. Is treatment-associated hypomania rare with duloxetine: secondary analysis of controlled trials in non-bipolar depression. Journal of Affective Disorders. 87: 115-9. PMID 15967235 DOI: 10.1016/j.jad.2005.02.017  0.221
2004 Goldstein DJ, Lu Y, Detke MJ, Wiltse C, Mallinckrodt C, Demitrack MA. Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine. Journal of Clinical Psychopharmacology. 24: 389-99. PMID 15232330 DOI: 10.1097/01.jcp.0000132448.65972.d9  0.221
2004 Detke MJ, Wiltse CG, Mallinckrodt CH, McNamara RK, Demitrack MA, Bitter I. Duloxetine in the acute and long-term treatment of major depressive disorder: a placebo- and paroxetine-controlled trial. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 14: 457-70. PMID 15589385 DOI: 10.1016/J.Euroneuro.2004.01.002  0.207
2005 Nelson JC, Wohlreich MM, Mallinckrodt CH, Detke MJ, Watkin JG, Kennedy JS. Duloxetine for the treatment of major depressive disorder in older patients. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 13: 227-35. PMID 15728754 DOI: 10.1176/appi.ajgp.13.3.227  0.198
2006 Perahia DG, Wang F, Mallinckrodt CH, Walker DJ, Detke MJ. Duloxetine in the treatment of major depressive disorder: a placebo- and paroxetine-controlled trial. European Psychiatry : the Journal of the Association of European Psychiatrists. 21: 367-78. PMID 16697153 DOI: 10.1016/j.eurpsy.2006.03.004  0.198
2002 Detke M, Lu Y, Goldstein D, Demitrack M. Duloxetine 60 mg QD is efficacious in the treatment of depression European Neuropsychopharmacology. 12: 215. DOI: 10.1016/S0924-977X(02)80233-4  0.197
2002 Detke M, Bitter I, Lu Y, Goldstein D, Demitrack M. Duloxetine 60 mg QD is efficacious in the treatment of depression European Psychiatry. 17: 98. DOI: 10.1016/S0924-9338(02)80445-X  0.197
2006 Fava M, Detke MJ, Balestrieri M, Wang F, Raskin J, Perahia D. Management of depression relapse: re-initiation of duloxetine treatment or dose increase. Journal of Psychiatric Research. 40: 328-36. PMID 16678205 DOI: 10.1016/j.jpsychires.2005.06.005  0.196
2003 Mallinckrodt CH, Goldstein DJ, Detke MJ, Lu Y, Watkin JG, Tran PV. Duloxetine: A New Treatment for the Emotional and Physical Symptoms of Depression. Primary Care Companion to the Journal of Clinical Psychiatry. 5: 19-28. PMID 15156243  0.192
2007 Pritchett YL, Marciniak MD, Corey-Lisle PK, Berzon RA, Desaiah D, Detke MJ. Use of effect size to determine optimal dose of duloxetine in major depressive disorder. Journal of Psychiatric Research. 41: 311-8. PMID 16934840 DOI: 10.1016/J.Jpsychires.2006.06.013  0.187
2009 Perahia DG, Maina G, Thase ME, Spann ME, Wang F, Walker DJ, Detke MJ. Duloxetine in the prevention of depressive recurrences: a randomized, double-blind, placebo-controlled trial. The Journal of Clinical Psychiatry. 70: 706-16. PMID 19552867 DOI: 10.4088/JCP.08m04756  0.186
2007 Koponen H, Allgulander C, Erickson J, Dunayevich E, Pritchett Y, Detke MJ, Ball SG, Russell JM. Efficacy of duloxetine for the treatment of generalized anxiety disorder: implications for primary care physicians. Primary Care Companion to the Journal of Clinical Psychiatry. 9: 100-7. PMID 17607331  0.185
2002 Goldstein D, Bitter I, Lu Y, Detke M, Wiltse C, Mallinckrodt C, Demitrack M. Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine European Psychiatry. 17: 98. DOI: 10.1016/S0924-9338(02)80446-1  0.185
2003 Khan A, Detke M, Khan SRF, Mallinckrodt C. Placebo response and antidepressant clinical trial outcome Journal of Nervous and Mental Disease. 191: 211-218. PMID 12695731 DOI: 10.1097/00005053-200304000-00001  0.183
2002 Detke MJ, Lu Y, Goldstein DJ, Hayes JR, Demitrack MA. Duloxetine, 60 mg once daily, for major depressive disorder: a randomized double-blind placebo-controlled trial. The Journal of Clinical Psychiatry. 63: 308-15. PMID 12000204  0.181
2007 Shelton RC, Prakash A, Mallinckrodt CH, Wohlreich MM, Raskin J, Robinson MJ, Detke MJ. Patterns of depressive symptom response in duloxetine-treated outpatients with mild, moderate or more severe depression. International Journal of Clinical Practice. 61: 1337-48. PMID 17627710 DOI: 10.1111/j.1742-1241.2007.01444.x  0.181
2014 Shen JH, Zhao Y, Rosenzweig-Lipson S, Popp D, Williams JB, Giller E, Detke MJ, Kane JM. A 6-week randomized, double-blind, placebo-controlled, comparator referenced trial of vabicaserin in acute schizophrenia. Journal of Psychiatric Research. 53: 14-22. PMID 24613032 DOI: 10.1016/j.jpsychires.2014.02.012  0.181
2008 Fishbain DA, Detke MJ, Wernicke J, Chappell AS, Kajdasz DK. The relationship between antidepressant and analgesic responses: findings from six placebo-controlled trials assessing the efficacy of duloxetine in patients with major depressive disorder. Current Medical Research and Opinion. 24: 3105-15. PMID 18828958 DOI: 10.1185/03007990802429627  0.179
2008 Rynn M, Russell J, Erickson J, Detke MJ, Ball S, Dinkel J, Rickels K, Raskin J. Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial. Depression and Anxiety. 25: 182-9. PMID 17311303 DOI: 10.1002/da.20271  0.179
2008 Kornstein SG, Dunner DL, Meyers AL, Whitmyer VG, Mallinckrodt CH, Wohlreich MM, Detke MJ, Hollandbeck MS, Greist JH. A randomized, double-blind study of increasing or maintaining duloxetine dose in patients without remission of major depressive disorder after initial duloxetine therapy. The Journal of Clinical Psychiatry. 69: 1383-92. PMID 19193339  0.178
2006 Nelson JC, Lu Pritchett Y, Martynov O, Yu JY, Mallinckrodt CH, Detke MJ. The safety and tolerability of duloxetine compared with paroxetine and placebo: a pooled analysis of 4 clinical trials. Primary Care Companion to the Journal of Clinical Psychiatry. 8: 212-9. PMID 16964316  0.177
2014 Fava M, Freeman M, Williams J, Detke M. EPA-1780 – Are different methods to reduce placebo response in cns trials mutually exclusive or have additive effects? European Psychiatry. 29: 1. DOI: 10.1016/S0924-9338(14)78903-5  0.176
2007 Shelton RC, Andorn AC, Mallinckrodt CH, Wohlreich MM, Raskin J, Watkin JG, Detke MJ. Evidence for the efficacy of duloxetine in treating mild, moderate, and severe depression. International Clinical Psychopharmacology. 22: 348-55. PMID 17917553 DOI: 10.1097/YIC.0b013e32821c6189  0.175
2008 Allgulander C, Nutt D, Detke M, Erickson J, Spann M, Walker D, Ball SG, Russell JM. A non-inferiority comparison of duloxetine and venlafaxine in the treatment of adult patients with generalized anxiety disorder Journal of Psychopharmacology. 22: 417-425. PMID 18635722 DOI: 10.1177/0269881108091588  0.175
2005 Delgado PL, Brannan SK, Mallinckrodt CH, Tran PV, McNamara RK, Wang F, Watkin JG, Detke MJ. Sexual functioning assessed in 4 double-blind placebo- and paroxetine-controlled trials of duloxetine for major depressive disorder. The Journal of Clinical Psychiatry. 66: 686-92. PMID 15960560  0.171
2007 Hartford J, Kornstein S, Liebowitz M, Pigott T, Russell J, Detke M, Walker D, Ball S, Dunayevich E, Dinkel J, Erickson J. Duloxetine as an SNRI treatment for generalized anxiety disorder: Results from a placebo and active-controlled trial International Clinical Psychopharmacology. 22: 167-174. PMID 17414743 DOI: 10.1097/Yic.0B013E32807Fb1B2  0.171
2005 Hirschfeld RM, Mallinckrodt C, Lee TC, Detke MJ. Time course of depression-symptom improvement during treatment with duloxetine. Depression and Anxiety. 21: 170-7. PMID 16035056 DOI: 10.1002/da.20071  0.17
2010 Mallinckrodt CH, Detke MJ, Prucka WR, Ruberg SJ, Molenberghs G. Considerations for comparing a test drug with standard of care in phase 2 clinical trials of central nervous system disorders Drug Information Journal. 44: 443-452.  0.169
2004 Goldstein DJ, Lu Y, Detke MJ, Hudson J, Iyengar S, Demitrack MA. Effects of duloxetine on painful physical symptoms associated with depression. Psychosomatics. 45: 17-28. PMID 14709757 DOI: 10.1176/appi.psy.45.1.17  0.168
2008 Russell IJ, Mease PJ, Smith TR, Kajdasz DK, Wohlreich MM, Detke MJ, Walker DJ, Chappell AS, Arnold LM. Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial. Pain. 136: 432-44. PMID 18395345 DOI: 10.1016/j.pain.2008.02.024  0.165
2005 Brannan SK, Mallinckrodt CH, Detke MJ, Watkin JG, Tollefson GD. Onset of action for duloxetine 60 mg once daily: double-blind, placebo-controlled studies. Journal of Psychiatric Research. 39: 161-72. PMID 15589564 DOI: 10.1016/j.jpsychires.2004.05.005  0.161
2008 Davidson JR, Wittchen HU, Llorca PM, Erickson J, Detke M, Ball SG, Russell JM. Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 18: 673-81. PMID 18559291 DOI: 10.1016/j.euroneuro.2008.05.002  0.156
2010 Mallinckrodt CH, Detke MJ, Prucka WR, Ruberg SJ, Molenberghs G. Design Archetypes for Phase 2 Clinical Trials in Central Nervous System Disorders Drug Information Journal. 44: 421-430. DOI: 10.1177/009286151004400406  0.153
2004 Arnold LM, Lu Y, Crofford LJ, Wohlreich M, Detke MJ, Iyengar S, Goldstein DJ. A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. Arthritis and Rheumatism. 50: 2974-84. PMID 15457467 DOI: 10.1002/art.20485  0.153
2006 Pritchett Y, McCarberg B, Watkin J, Chappell A, Robinson M, Xu J, Rotz B, Wernicke J, Detke M, Iyengar S, Henck J, Bymaster F, Callaghan J, Knadler M, Thase M, et al. Abstracts from the ASENT 2006 Annual Meeting March 8–11, 2006 Neurorx. 3: 407-415. DOI: 10.1016/J.Nurx.2006.05.010  0.153
2010 Pangallo BA, Zhang Q, Desaiah D, Perahia DG, Detke MJ, Kennedy SH. Long-term safety of duloxetine during open-label compassionate use treatment of patients who completed previous duloxetine clinical trials. Current Medical Research and Opinion. 26: 2643-51. PMID 20932222 DOI: 10.1185/03007995.2010.522157  0.151
2003 Wohlreich M, Mallinckrodt C, Lu Y, Detke M. The efficacy of duloxetine (60 mg qd) in the treatment of painful physical symptoms in patients with major depressive disorder Journal of Psychosomatic Research. 55: 157. DOI: 10.1016/S0022-3999(03)00200-9  0.151
2004 Mallinckrodt CH, Raskin J, Wohlreich MM, Watkin JG, Detke MJ. The efficacy of duloxetine: a comprehensive summary of results from MMRM and LOCF_ANCOVA in eight clinical trials. Bmc Psychiatry. 4: 26. PMID 15355546 DOI: 10.1186/1471-244X-4-26  0.15
2004 Viktrup L, Pangallo BA, Detke MJ, Zinner NR. Urinary Side Effects of Duloxetine in the Treatment of Depression and Stress Urinary Incontinence. Primary Care Companion to the Journal of Clinical Psychiatry. 6: 65-73. PMID 15254599  0.148
2013 Popp D, Burch R, Williams J, Price L, Detke M. 2210 – A phase II randomized, double-blind, placebo-controlled trial of GLYX-13 for the rapid treatment of major depressive disorder using central ratings European Psychiatry. 28: 1. DOI: 10.1016/S0924-9338(13)77083-4  0.147
2005 Burt VK, Wohlreich MM, Mallinckrodt CH, Detke MJ, Watkin JG, Stewart DE. Duloxetine for the treatment of major depressive disorder in women ages 40 to 55 years. Psychosomatics. 46: 345-54. PMID 16000678 DOI: 10.1176/appi.psy.46.4.345  0.145
2003 Detke M, Gilaberte I, Perahia D, Wang F, McNamara R, Tran P, Miner C, Montgomery S. P.1.204 Duloxetine vs placebo in the prevention of relapse of major depressive disorder European Neuropsychopharmacology. 13: S261-S262. DOI: 10.1016/S0924-977X(03)91914-6  0.145
2005 Goldstein DJ, Lu Y, Detke MJ, Lee TC, Iyengar S. Duloxetine vs. placebo in patients with painful diabetic neuropathy. Pain. 116: 109-18. PMID 15927394 DOI: 10.1016/j.pain.2005.03.029  0.143
2006 Alpert J, Detke M, Lecrubier Y, Schläpfer T. C.12.01 Current controversies in depression treatment: a hot topics panel European Neuropsychopharmacology. 16: S581. DOI: 10.1016/S0924-977X(06)70842-2  0.142
2013 Popp D, Burch R, Williams J, Price L, Detke M. P.2.b.027 A phase II randomized, double-blind, placebo-controlled trial of GLYX-13 for the rapid treatment of major depressive disorder (MDD) using central ratings European Neuropsychopharmacology. 23: S334-S335. DOI: 10.1016/S0924-977X(13)70526-1  0.142
2010 Mease PJ, Russell IJ, Kajdasz DK, Wiltse CG, Detke MJ, Wohlreich MM, Walker DJ, Chappell AS. Long-term safety, tolerability, and efficacy of duloxetine in the treatment of fibromyalgia. Seminars in Arthritis and Rheumatism. 39: 454-64. PMID 19152958 DOI: 10.1016/j.semarthrit.2008.11.001  0.142
2002 Lu Y, Tran P, Detke M. Remission rates during treatment with duloxetine in patients with major depressive disorder European Neuropsychopharmacology. 12: 214. DOI: 10.1016/S0924-977X(02)80230-9  0.137
2010 Mallinckrodt CH, Detke MJ, Prucka WR, Ruberg SJ, Molenberghs G. Considerations for Using Positive Controls in Phase 2 Clinical Trials of Central Nervous System Disorders Drug Information Journal. 44: 431-441. DOI: 10.1177/009286151004400407  0.136
2008 Pollack MH, Endicott J, Liebowitz M, Russell J, Detke M, Spann M, Ball S, Swindle R. Examining quality of life in patients with generalized anxiety disorder: Clinical relevance and response to duloxetine treatment Journal of Psychiatric Research. 42: 1042-1049. PMID 18221755 DOI: 10.1016/J.Jpsychires.2007.11.006  0.136
2007 Endicott J, Russell JM, Raskin J, Detke MJ, Erickson J, Ball SG, Marciniak M, Swindle RW. Duloxetine treatment for role functioning improvement in generalized anxiety disorder: three independent studies. The Journal of Clinical Psychiatry. 68: 518-24. PMID 17474806 DOI: 10.4088/Jcp.V68N0405  0.135
2011 Montejo AL, Perahia DG, Spann ME, Wang F, Walker DJ, Yang CR, Detke MJ. Sexual function during long-term duloxetine treatment in patients with recurrent major depressive disorder. The Journal of Sexual Medicine. 8: 773-82. PMID 21091877 DOI: 10.1111/j.1743-6109.2010.02113.x  0.134
2014 Potter WZ, Mallinckrodt CH, Detke MJ. Controlling placebo response in drug development: Lessons learned from psychopharmacology Pharmaceutical Medicine. 28: 53-65. DOI: 10.1007/s40290-014-0052-8  0.132
2007 Mallinckrodt C, Chuang-Stein C, McSorley P, Schwartz J, Archibald DG, Perahia DG, Detke MJ, Alphs L. A case study comparing a randomized withdrawal trial and a double-blind long-term trial for assessing the long-term efficacy of an antidepressant. Pharmaceutical Statistics. 6: 9-22. PMID 17238129 DOI: 10.1002/pst.234  0.13
2002 Goldstein D, Detke M, Lu Y, Demitrack M. The antidepressant duloxetine reduces anxiety symptom severity European Neuropsychopharmacology. 12: 213. DOI: 10.1016/S0924-977X(02)80229-2  0.13
2015 Williams JB, Kobak KA, Giller E, Reasner DS, Curry L, Detke MJ. Comparison of Site-Based Versus Central Ratings in a Study of Generalized Anxiety Disorder. Journal of Clinical Psychopharmacology. PMID 26488677 DOI: 10.1097/JCP.0000000000000422  0.128
2004 Swindle R, Mallinckrodt C, Rosebaum J, Lu Y, Watkin J, Ghandi P, Detke M. P.1.040 Efficacy of duloxetine treatment: Analysis of pooled data from six placebo- and SSRI-controlled clinical trials European Neuropsychopharmacology. 14: S190. DOI: 10.1016/S0924-977X(04)80129-9  0.127
2009 Schneider E, Skljarevski V, Desaiah D, Zhang Q, Chappell A, Detke M, Gross J. Wirkung von einmal täglich 60mg Duloxetin bei Patienten mit Schmerzen bei diabetischer Polyneuropathie: Ergebnisse einer offenen Langzeitstudie Diabetologie Und Stoffwechsel. 4. DOI: 10.1055/S-0029-1221964  0.125
2004 Fava M, Mallinckrodt CH, Detke MJ, Watkin JG, Wohlreich MM. The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates? The Journal of Clinical Psychiatry. 65: 521-30. PMID 15119915 DOI: 10.4088/JCP.v65n0411  0.125
2011 Detke M, Williams J, Kobak K, Ellis A, Giller E, Brown B, Reines S, Kane J, Popp D. P.8.a.013 The challenge of subject selection in clinical trials European Neuropsychopharmacology. 21: S618. DOI: 10.1016/S0924-977X(11)71011-2  0.124
2003 Wohlreich M, Brannan S, Mallinckrodt C, Detke M, Lu Y, Watkin J, Tollefson G. P.1.035 Onset of improvement in emotional and painful physical symptoms of depression with duloxetine treatment European Neuropsychopharmacology. 13: S189. DOI: 10.1016/S0924-977X(03)91746-9  0.114
2002 Tran P, Mallinckrodt C, Detke M, Goldstein D, Demitrack M. Safety and tolerability of the antidepressant duloxetine European Neuropsychopharmacology. 12: 215-216. DOI: 10.1016/S0924-977X(02)80235-8  0.11
2009 Skljarevski V, Desaiah D, Zhang Q, Chappell AS, Detke MJ, Gross JL, Ziegler D. Evaluating the maintenance of effect of duloxetine in patients with diabetic peripheral neuropathic pain. Diabetes/Metabolism Research and Reviews. 25: 623-31. PMID 19637208 DOI: 10.1002/dmrr.1000  0.107
2003 Goldstein D, Lu Y, Iyengar S, Detke M. Duloxetine reduces painful physical symptoms associated with depression Journal of Psychosomatic Research. 55: 164. DOI: 10.1016/S0022-3999(03)00234-4  0.105
2006 Mallinckrodt CH, Detke MJ, Kaiser CJ, Watkin JG, Molenberghs G, Carroll RJ. Comparing onset of antidepressant action using a repeated measures approach and a traditional assessment schedule. Statistics in Medicine. 25: 2384-97. PMID 16217850 DOI: 10.1002/Sim.2309  0.103
2010 Skljarevski V, Desaiah D, Liu-Seifert H, Zhang Q, Chappell AS, Detke MJ, Iyengar S, Atkinson JH, Backonja M. Efficacy and safety of duloxetine in patients with chronic low back pain. Spine. 35: E578-85. PMID 20461028 DOI: 10.1097/BRS.0b013e3181d3cef6  0.103
2013 Chappell JC, Kovacs R, Haber H, Wright R, Mitchell MI, Detke M, Pangallo B. Evaluation of the effects of duloxetine and escitalopram on 24-hour heart rate variability: A mechanistic study using heart rate variability as a pharmacodynamic measure Journal of Clinical Psychopharmacology. 33: 236-239. PMID 23422380 DOI: 10.1097/JCP.0b013e31828567b6  0.102
2008 Chappell AS, Bradley LA, Wiltse C, Detke MJ, D'Souza DN, Spaeth M. A six-month double-blind, placebo-controlled, randomized clinical trial of duloxetine for the treatment of fibromyalgia. International Journal of General Medicine. 1: 91-102. PMID 20428412  0.099
2003 Thase M, Lu Y, Joliat M, Detke M. P.1.096 Remission rates in double-blind, placebo-controlled clinical trials of duloxetine with SSRI as a comparator European Neuropsychopharmacology. 13: S215. DOI: 10.1016/S0924-977X(03)91806-2  0.098
2003 Wohlreich M, Fava M, Mallinckrodt C, Watkin J, Detke M. Does the alleviation of painful physical symptoms associated with depression lead to higher remission rates? Journal of Psychosomatic Research. 55: 157-158. DOI: 10.1016/S0022-3999(03)00201-0  0.096
2015 Kiluk BD, Carroll KM, Duhig A, Falk DE, Kampman K, Lai S, Litten RZ, McCann DJ, Montoya ID, Preston KL, Skolnick P, Weisner C, Woody G, Chandler R, Detke MJ, et al. Measures of outcome for stimulant trials: ACTTION recommendations and research agenda. Drug and Alcohol Dependence. PMID 26652899 DOI: 10.1016/J.Drugalcdep.2015.11.004  0.094
2012 Williams J, Popp D, Kobak K, Detke M. P-641 - The importance of rigor in post-baseline assessments in cns clinical trials European Psychiatry. 27: 1. DOI: 10.1016/S0924-9338(12)74808-3  0.093
2011 Williams J, Kobak K, Detke M. P.8.a.014 The importance of rigor in post-baseline assessments in CNS clinical trials European Neuropsychopharmacology. 21: S618-S619. DOI: 10.1016/S0924-977X(11)71012-4  0.093
2006 DETKE M, IYENGAR S, HENCK J, BYMASTER F, CALLAGHAN J, KNADLER M, CHAPPELL A, WERNICKE J, THASE M. Cardiovascular Effects of Duloxetine: Preclinical and Clinical Findings Neurorx. 3: 407-408. DOI: 10.1016/J.NURX.2006.05.012  0.09
2016 Detke M, Negash S, Webber-Lind B, Sorantin P, Williams J. Error reductions over time in Virgil eCOA versus paper-based administrations in psychiatry trials European Neuropsychopharmacology. 26: S470-S471. DOI: 10.1016/S0924-977X(16)31470-5  0.089
2012 Popp D, Williams J, Kobak K, Boehm P, Detke M. P3-382: The role of expectation bias in neurocognitive clinical trials Alzheimer's & Dementia. 8: P589-P590. DOI: 10.1016/j.jalz.2012.05.1607  0.083
2009 Skljarevski V, Ossanna M, Liu-Seifert H, Zhang Q, Chappell A, Iyengar S, Detke M, Backonja M. A double-blind, randomized trial of duloxetine versus placebo in the management of chronic low back pain European Journal of Neurology. 16: 1041-1048. PMID 19469829 DOI: 10.1111/j.1468-1331.2009.02648.x  0.081
2012 Williams J, Popp D, Osman D, Cohen E, Detke M. P.3.a.010 The use of the 16 item Negative Symptom Assessment (NSA-16) by videoconferencing in a clinical trial European Neuropsychopharmacology. 22: S309. DOI: 10.1016/S0924-977X(12)70472-8  0.08
1989 Detke MJ, Brandon SE, Weingarten HP, Rodin J, Wagner AR. Modulation of behavioral and insulin responses by contextual stimuli paired with food. Physiology & Behavior. 45: 845-51. PMID 2675142 DOI: 10.1016/0031-9384(89)90305-3  0.079
2012 Williams J, Popp D, Reines S, Detke M. P.1.i.009 Some urban legends of CNS clinical trial methodology: unsuccessful solutions to the problem of failed trials European Neuropsychopharmacology. 22: S223-S224. DOI: 10.1016/S0924-977X(12)70329-2  0.077
2012 Williams J, Popp D, Osman D, Cohen E, Detke M. Poster #177 THE USE OF THE NSA-16 BY VIDEOCONFERENCING IN A CLINICAL TRIAL Schizophrenia Research. 136: S344-S345. DOI: 10.1016/S0920-9964(12)71009-5  0.075
2013 Williams J, Popp D, Osman D, Cohen E, Detke M. 1922 – The evaluation of negative symptoms by videoconferencing in a clinical trial European Psychiatry. 28: 1. DOI: 10.1016/S0924-9338(13)76868-8  0.074
2007 Bodkin JA, Pope HG, Detke MJ, Hudson JI. Is PTSD caused by traumatic stress? Journal of Anxiety Disorders. 21: 176-82. PMID 17055216 DOI: 10.1016/j.janxdis.2006.09.004  0.074
2010 Detke M, Williams J, Kobath K, Ellis A, Giller E, Leon A, Reines S, Kane J. THE CHALLENGE OF PATIENT ASCERTAINMENT IN CLINICAL TRIALS – NEW DATA Schizophrenia Research. 117: 406. DOI: 10.1016/j.schres.2010.02.741  0.073
2012 Popp D, Williams JB, Sorantin P, Detke M. P2-304: Guidelines for reporting clinical trial methodology research: The seven deadly sins Alzheimer's & Dementia. 8: P369-P370. DOI: 10.1016/j.jalz.2012.05.1013  0.067
2009 Shoemaker S, Backonja MM, Chappell A, Detke M, Murray I, Skljarevski V, Zhang S. Poster 55: Maintenance of Effect of Duloxetine in Patients With Chronic Lower Back Pain Pm&R. 1: S127-S128. DOI: 10.1016/j.pmrj.2009.08.072  0.067
2009 Skljarevski V, Zhang S, Chappell A, Detke M, Murray I, Backonja M. 674 MAINTENANCE OF EFFECT OF DULOXETINE IN PATIENTS WITH CHRONIC LOW BACK PAIN European Journal of Pain. 13. DOI: 10.1016/S1090-3801(09)60677-7  0.064
2004 Mallinckrodt CH, Kaiser CJ, Watkin JG, Detke MJ, Molenbergs G, Carroll RJ. Type 1 error rates from likelihood-based repeated measures analyses of incomplete longitudinal data Pharmaceutical Statistics. 3: 171-186. DOI: 10.1002/Pst.131  0.063
2013 Williams J, Davis D, Popp D, Gross J, Salvucci D, Detke M. 1902 – Feasibility of centralized ratings for mental health safety screening in a non-psychiatric clinical trial European Psychiatry. 28: 1. DOI: 10.1016/S0924-9338(13)76853-6  0.06
2010 Mallinckrodt CH, Detke MJ, Prucka WR, Ruberg SJ, Molenberghs G. Design archetypes for phase 2 clinical trials in central nervous system disorders Drug Information Journal. 44: 421-430.  0.056
2010 Mallinckrodt CH, Detke MJ, Prucka WR, Ruberg SJ, Molenberghs G. Considerations for using positive controls in phase 2 clinical trials of central nervous system disorders Drug Information Journal. 44: 431-441.  0.053
2015 Detke M, Echevarria B, Osman D, Garzio L, Williams J. P.1.k.033 A new platform to improve quality of PANNS and MADRS administration European Neuropsychopharmacology. 25: S371-S372. DOI: 10.1016/S0924-977X(15)30479-X  0.053
2017 Detke M, Connor G, Kelsh D, Straub J, Robbins A, Gloff C, Goeders N. A phase 1b study of potential safety and pharmacokinetic interactions between cocaine and EMB-001, with exploratory efficacy measures European Neuropsychopharmacology. 27: S1073. DOI: 10.1016/S0924-977X(17)31868-0  0.052
2013 Williams J, Popp D, Price L, Gross J, Davis D, Salvucci D, Detke M. P.8.b.004 Feasibility of centralised ratings for mental health safety screening in a dermatology trial European Neuropsychopharmacology. 23: S621-S622. DOI: 10.1016/S0924-977X(13)70987-8  0.051
2010 Detke M. IMPROVING SIGNAL DETECTION IN SCHIZOPHRENIA CLINICAL TRIALS Schizophrenia Research. 117: 138. DOI: 10.1016/j.schres.2010.02.107  0.041
2009 Wilhelm S, Skljarevski V, Desaiah D, Zhang Q, Chappell A, Detke M, Schneider E, Gross J. Aufrechterhaltung der Wirkung von Duloxetin bei Patienten mit Schmerzen bei diabetischer Polyneuropathie Aktuelle Neurologie. 36. DOI: 10.1055/s-0029-1238539  0.039
2012 Williams J, Popp D, Kobak K, Detke M. P-640 - The power of expectation bias European Psychiatry. 27: 1. DOI: 10.1016/S0924-9338(12)74807-1  0.022
2011 Williams J, Popp D, Kobak K, Detke M. P.8.a.015 The power of expectation bias European Neuropsychopharmacology. 21: S619. DOI: 10.1016/S0924-977X(11)71013-6  0.022
2012 Popp D, Williams J, Cohen E, Detke M. Poster #176 NSA-16 REVISITED: IDENTIFYING LATENT FACTORS OF NEGATIVE SYMPTOMS IN SCHIZOPHRENIA Schizophrenia Research. 136: S344. DOI: 10.1016/S0920-9964(12)71008-3  0.017
2009 Aboud E, Bonnard C, Chappell A, Skljareversuski V, Desaiah D, Zhang Q, Detke M, Gross J, Pechtner V. O80 Évaluation de l’effet de la duloxétine dans la neuropathie diabétique périphérique douloureuse Diabetes & Metabolism. 35: A21. DOI: 10.1016/S1262-3636(09)71772-0  0.01
2007 Iyengar S, Pritchett Y, Hall J, Chappell A, Wernicke J, Goldstein D, Simmons R, Detke M, Shen S, D'Souza D, Schneider E, Robinson M. Die Zeit bis zum Ansprechen auf Duloxetin: Ergebnisse zur Übersicht über die Daten aus Zeitdauer bis zum Ansprechen aus präklinischen und klinischen Studien zu neuropathischen Schmerzen Diabetologie Und Stoffwechsel. 2. DOI: 10.1055/S-2007-982355  0.01
2006 Pritchett Y, McCarberg B, Watkin J, Chappell A, Robinson M, Xu J, Rotz B, Wernicke J, Detke M, Iyengar S, Henck J, Bymaster F, Callaghan J, Knadler M, Thase M, et al. Abstracts from the ASENT 2006 Annual Meeting March 8–11, 2006 Neurotherapeutics. 3: 407-415. DOI: 10.1007/bf03206663  0.01
Hide low-probability matches.