Jeffrey A. Loeb, MD/PHD - Publications

Affiliations: 
1998-2013 Center for Molecular Medicine & Genetics, Dept. of Neurology Wayne State University School of Medicine, Detroit, MI, United States 
 2013- Neurology University of Ilinois, Chicago 
Area:
Epilepsy, Neuregulin

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Maharathi B, Wlodarski R, Bagla S, Asano E, Hua J, Patton J, Loeb JA. Interictal spike connectivity in human epileptic neocortex. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 130: 270-279. PMID 30605889 DOI: 10.1016/j.clinph.2018.11.025  0.4
2018 Keren-Aviram G, Dachet F, Bagla S, Balan K, Loeb JA, Dratz EA. Proteomic analysis of human epileptic neocortex predicts vascular and glial changes in epileptic regions. Plos One. 13: e0195639. PMID 29634780 DOI: 10.1371/journal.pone.0195639  0.4
2017 Wu HC, Dachet F, Ghoddoussi F, Bagla S, Fuerst D, Stanley JA, Galloway MP, Loeb JA. Altered metabolomic-genomic signature: A potential noninvasive biomarker of epilepsy. Epilepsia. PMID 28714074 DOI: 10.1111/epi.13848  0.4
2017 Barry G, Briggs JA, Hwang DW, Nayler SP, Fortuna PR, Jonkhout N, Dachet F, Maag JL, Mestdagh P, Singh EM, Avesson L, Kaczorowski DC, Ozturk E, Jones NC, Vetter I, ... ... Loeb JA, et al. The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states. Scientific Reports. 7: 40127. PMID 28054653 DOI: 10.1038/srep40127  0.4
2015 Mittal S, Barkmeier D, Hua J, Pai DS, Fuerst D, Basha M, Loeb JA, Shah AK. Intracranial EEG analysis in tumor-related epilepsy: Evidence of distant epileptic abnormalities. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. PMID 26493495 DOI: 10.1016/j.clinph.2015.06.028  0.36
2015 Boutros NN, Bowyer S, Wang J, Urfy MZ, Loeb JA. Epilepsy spectrum disorders: A concept in need of validation or refutation. Medical Hypotheses. PMID 26319642 DOI: 10.1016/j.mehy.2015.08.004  0.36
2015 Nash TE, Mahanty S, Loeb JA, Theodore WH, Friedman A, Sander JW, Singh G, Cavalheiro E, Del Brutto OH, Takayanagui OM, Fleury A, Verastegui M, Preux PM, Montano S, Pretell EJ, et al. In response: Multifactorial basis of epilepsy in patients with neurocysticercosis. Epilepsia. 56: 975-6. PMID 26040533 DOI: 10.1111/epi.12986  0.36
2015 Wang J, Hmadcha A, Zakarian V, Song F, Loeb JA. Rapid transient isoform-specific neuregulin1 transcription in motor neurons is regulated by neurotrophic factors and axon-target interactions. Molecular and Cellular Neurosciences. 68: 73-81. PMID 25913151 DOI: 10.1016/j.mcn.2015.04.003  0.36
2015 Serafini R, Andrade R, Loeb JA. Coalescence of deep and superficial epileptic foci into larger discharge units in adult rat neocortex. Neuroscience. 292: 148-58. PMID 25701714 DOI: 10.1016/j.neuroscience.2015.02.017  0.36
2015 Nash TE, Mahanty S, Loeb JA, Theodore WH, Friedman A, Sander JW, Singh G, Cavalheiro E, Del Brutto OH, Takayanagui OM, Fleury A, Verastegui M, Preux PM, Montano S, Pretell EJ, et al. Neurocysticercosis: A natural human model of epileptogenesis. Epilepsia. 56: 177-83. PMID 25534640 DOI: 10.1111/epi.12849  0.36
2015 Dachet F, Bagla S, Keren-Aviram G, Morton A, Balan K, Saadat L, Valyi-Nagy T, Kupsky W, Song F, Dratz E, Loeb JA. Predicting novel histopathological microlesions in human epileptic brain through transcriptional clustering. Brain : a Journal of Neurology. 138: 356-70. PMID 25516101 DOI: 10.1093/brain/awu350  0.36
2015 Serafini R, Loeb JA. Enhanced slow waves at the periphery of human epileptic foci. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 126: 1117-23. PMID 25454344 DOI: 10.1016/j.clinph.2014.08.023  0.36
2014 Rossignol E, Kobow K, Simonato M, Loeb JA, Grisar T, Gilby KL, Vinet J, Kadam SD, Becker AJ. WONOEP appraisal: new genetic approaches to study epilepsy. Epilepsia. 55: 1170-86. PMID 24965021 DOI: 10.1111/epi.12692  0.36
2014 Song F, Chiang P, Ravits J, Loeb JA. Activation of microglial neuregulin1 signaling in the corticospinal tracts of ALS patients with upper motor neuron signs. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 15: 77-83. PMID 24229388 DOI: 10.3109/21678421.2013.853802  0.36
2014 Kim EGR, John JK, Tu H, Zheng Q, Loeb J, Zhang J, Xu Y. A hybrid silicon-parylene neural probe with locally flexible regions Sensors and Actuators, B: Chemical. 195: 416-422. DOI: 10.1016/j.snb.2014.01.048  0.36
2013 Mittal S, Shah AK, Barkmeier DT, Loeb JA. Systems biology of human epilepsy applied to patients with brain tumors. Epilepsia. 54: 35-9. PMID 24328870 DOI: 10.1111/epi.12441  0.36
2013 Engel J, Pitkänen A, Loeb JA, Dudek FE, Bertram EH, Cole AJ, Moshé SL, Wiebe S, Jensen FE, Mody I, Nehlig A, Vezzani A. Epilepsy biomarkers. Epilepsia. 54: 61-9. PMID 23909854 DOI: 10.1111/epi.12299  0.36
2013 Galanopoulou AS, Kokaia M, Loeb JA, Nehlig A, Pitkänen A, Rogawski MA, Staley KJ, Whittemore VH, Dudek FE. Epilepsy therapy development: technical and methodologic issues in studies with animal models. Epilepsia. 54: 13-23. PMID 23909850 DOI: 10.1111/epi.12295  0.36
2013 Song F, Bandara M, Deol H, Loeb JA, Benjamins J, Lisak RP. Complexity of trophic factor signaling in experimental autoimmune encephalomyelitis: differential expression of neurotrophic and gliotrophic factors. Journal of Neuroimmunology. 262: 11-8. PMID 23763772 DOI: 10.1016/j.jneuroim.2013.05.012  0.36
2013 Jeng D, Ma Z, Barrett JW, McFadden G, Loeb JA, Essani K. The tanapoxvirus 15L protein is a virus-encoded neuregulin that promotes viral replication in human endothelial cells. Journal of Virology. 87: 3018-26. PMID 23269801 DOI: 10.1128/JVI.02112-12  0.36
2013 John JK, Kim E, Tu H, Zhang J, Loeb JA, Xu Y. Multifunctional chronic 3D electrode arrays based on a simple folding process 2013 Transducers and Eurosensors Xxvii: the 17th International Conference On Solid-State Sensors, Actuators and Microsystems, Transducers and Eurosensors 2013. 1476-1479. DOI: 10.1109/Transducers.2013.6627059  0.36
2013 Wang J, Ma Z, Loeb JA. Cell-Specific Targeting of Fusion Proteins through Heparin Binding Fusion Protein Technologies For Biopharmaceuticals: Applications and Challenges. 413-427. DOI: 10.1002/9781118354599.ch27  0.36
2012 Beaumont TL, Yao B, Shah A, Kapatos G, Loeb JA. Layer-specific CREB target gene induction in human neocortical epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14389-401. PMID 23055509 DOI: 10.1523/JNEUROSCI.3408-12.2012  0.36
2012 Lipovich L, Dachet F, Cai J, Bagla S, Balan K, Jia H, Loeb JA. Activity-dependent human brain coding/noncoding gene regulatory networks. Genetics. 192: 1133-48. PMID 22960213 DOI: 10.1534/genetics.112.145128  0.36
2012 Simonato M, Löscher W, Cole AJ, Dudek FE, Engel J, Kaminski RM, Loeb JA, Scharfman H, Staley KJ, Velíšek L, Klitgaard H. Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design. Epilepsia. 53: 1860-7. PMID 22708847 DOI: 10.1111/j.1528-1167.2012.03541.x  0.36
2012 Barkmeier DT, Senador D, Leclercq K, Pai D, Hua J, Boutros NN, Kaminski RM, Loeb JA. Electrical, molecular and behavioral effects of interictal spiking in the rat. Neurobiology of Disease. 47: 92-101. PMID 22472188 DOI: 10.1016/j.nbd.2012.03.026  0.36
2012 Yadav R, Shah AK, Loeb JA, Swamy MN, Agarwal R. Morphology-based automatic seizure detector for intracerebral EEG recordings. Ieee Transactions On Bio-Medical Engineering. 59: 1871-81. PMID 22434792 DOI: 10.1109/TBME.2012.2190601  0.36
2012 Song F, Chiang P, Wang J, Ravits J, Loeb JA. Aberrant neuregulin 1 signaling in amyotrophic lateral sclerosis. Journal of Neuropathology and Experimental Neurology. 71: 104-15. PMID 22249457 DOI: 10.1097/NEN.0b013e3182423c43  0.36
2012 Barkmeier DT, Shah AK, Flanagan D, Atkinson MD, Agarwal R, Fuerst DR, Jafari-Khouzani K, Loeb JA. High inter-reviewer variability of spike detection on intracranial EEG addressed by an automated multi-channel algorithm. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 123: 1088-95. PMID 22033028 DOI: 10.1016/j.clinph.2011.09.023  0.36
2011 Yadav R, Shah AK, Loeb JA, Swamy MN, Agarwal R. A novel unsupervised spike sorting algorithm for intracranial EEG. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 7545-8. PMID 22256084 DOI: 10.1109/IEMBS.2011.6091860  0.36
2011 Ma Z, Wang J, Song F, Loeb JA. Critical period of axoglial signaling between neuregulin-1 and brain-derived neurotrophic factor required for early Schwann cell survival and differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9630-40. PMID 21715628 DOI: 10.1523/JNEUROSCI.1659-11.2011  0.36
2011 Loeb JA. Identifying targets for preventing epilepsy using systems biology. Neuroscience Letters. 497: 205-12. PMID 21382442 DOI: 10.1016/j.neulet.2011.02.041  0.36
2011 Calvo M, Zhu N, Grist J, Ma Z, Loeb JA, Bennett DL. Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway. Glia. 59: 554-68. PMID 21319222 DOI: 10.1002/glia.21124  0.36
2011 John J, Li Y, Zhang J, Loeb JA, Xu Y. Microfabrication of 3D neural probes with combined electrical and chemical interfaces Journal of Micromechanics and Microengineering. 21. DOI: 10.1088/0960-1317/21/10/105011  0.36
2010 Loeb JA. A human systems biology approach to discover new drug targets in epilepsy. Epilepsia. 51: 171-7. PMID 20618426 DOI: 10.1111/j.1528-1167.2010.02635.x  0.36
2010 de Guzman RC, Loeb JA, VandeVord PJ. Electrospinning of matrigel to deposit a basal lamina-like nanofiber surface. Journal of Biomaterials Science. Polymer Edition. 21: 1081-101. PMID 20507710 DOI: 10.1163/092050609X12457428936116  0.36
2010 Calvo M, Zhu N, Tsantoulas C, Ma Z, Grist J, Loeb JA, Bennett DL. Neuregulin-ErbB signaling promotes microglial proliferation and chemotaxis contributing to microgliosis and pain after peripheral nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5437-50. PMID 20392965 DOI: 10.1523/JNEUROSCI.5169-09.2010  0.36
2009 Barkmeier DT, Loeb JA. An animal model to study the clinical significance of interictal spiking. Clinical Eeg and Neuroscience. 40: 234-8. PMID 19780344  0.36
2009 Ma Z, Li Q, An H, Pankonin MS, Wang J, Loeb JA. Targeting human epidermal growth factor receptor signaling with the neuregulin's heparin-binding domain. The Journal of Biological Chemistry. 284: 32108-15. PMID 19717564 DOI: 10.1074/jbc.M109.032714  0.36
2009 Esper RM, Loeb JA. Neurotrophins induce neuregulin release through protein kinase Cdelta activation. The Journal of Biological Chemistry. 284: 26251-60. PMID 19648576 DOI: 10.1074/jbc.M109.002915  0.36
2009 Pankonin MS, Sohi J, Kamholz J, Loeb JA. Differential distribution of neuregulin in human brain and spinal fluid. Brain Research. 1258: 1-11. PMID 19150438 DOI: 10.1016/j.brainres.2008.12.047  0.32
2009 Loeb JA, Beaumont TL. What goes in is what comes out: How to design and implement a successful microarray experiment Bioinformatics For Systems Biology. 209-225. DOI: 10.1007/978-1-59745-440-7_12  0.36
2008 Rakhade SN, Loeb JA. Focal reduction of neuronal glutamate transporters in human neocortical epilepsy. Epilepsia. 49: 226-36. PMID 17868051 DOI: 10.1111/j.1528-1167.2007.01310.x  0.36
2007 Rakhade SN, Shah AK, Agarwal R, Yao B, Asano E, Loeb JA. Activity-dependent gene expression correlates with interictal spiking in human neocortical epilepsy. Epilepsia. 48: 86-95. PMID 17910586 DOI: 10.1111/j.1528-1167.2007.01294.x  0.36
2007 Loeb JA. Neuroprotection and repair by neurotrophic and gliotrophic factors in multiple sclerosis. Neurology. 68: S38-42; discussion S. PMID 17548567 DOI: 10.1212/01.wnl.0000275231.97764.43  0.36
2006 Shah AK, Agarwal R, Carhuapoma JR, Loeb JA. Compressed EEG pattern analysis for critically ill neurological-neurosurgical patients. Neurocritical Care. 5: 124-33. PMID 17099259 DOI: 10.1385/Neurocrit. Care 2006;05:124-133  0.36
2006 Nash TE, Singh G, White AC, Rajshekhar V, Loeb JA, Proaño JV, Takayanagui OM, Gonzalez AE, Butman JA, DeGiorgio C, Del Brutto OH, Delgado-Escueta A, Evans CA, Gilman RH, Martinez SM, et al. Treatment of neurocysticercosis: current status and future research needs. Neurology. 67: 1120-7. PMID 17030744 DOI: 10.1212/01.wnl.0000238514.51747.3a  0.36
2006 Hapner SJ, Nielsen KM, Chaverra M, Esper RM, Loeb JA, Lefcort F. NT-3 and CNTF exert dose-dependent, pleiotropic effects on cells in the immature dorsal root ganglion: neuregulin-mediated proliferation of progenitor cells and neuronal differentiation. Developmental Biology. 297: 182-97. PMID 16784738 DOI: 10.1016/j.ydbio.2006.05.007  0.36
2006 Loeb JA, Sohrab SA, Huq M, Fuerst DR. Brain calcifications induce neurological dysfunction that can be reversed by a bone drug. Journal of the Neurological Sciences. 243: 77-81. PMID 16430923 DOI: 10.1016/j.jns.2005.11.033  0.36
2006 Esper RM, Pankonin MS, Loeb JA. Neuregulins: versatile growth and differentiation factors in nervous system development and human disease. Brain Research Reviews. 51: 161-75. PMID 16412517 DOI: 10.1016/j.brainresrev.2005.11.006  0.36
2005 Rakhade SN, Yao B, Ahmed S, Asano E, Beaumont TL, Shah AK, Draghici S, Krauss R, Chugani HT, Sood S, Loeb JA. A common pattern of persistent gene activation in human neocortical epileptic foci. Annals of Neurology. 58: 736-47. PMID 16240350 DOI: 10.1002/ana.20633  0.36
2005 Pankonin MS, Gallagher JT, Loeb JA. Specific structural features of heparan sulfate proteoglycans potentiate neuregulin-1 signaling. The Journal of Biological Chemistry. 280: 383-8. PMID 15528194 DOI: 10.1074/jbc.M402645200  0.36
2004 Li Q, Ahmed S, Loeb JA. Development of an autocrine neuregulin signaling loop with malignant transformation of human breast epithelial cells. Cancer Research. 64: 7078-85. PMID 15466203 DOI: 10.1158/0008-5472.CAN-04-1152  0.36
2004 Maslinski PG, Loeb JA. Pica-associated cerebral edema in an adult. Journal of the Neurological Sciences. 225: 149-51. PMID 15465099 DOI: 10.1016/j.jns.2004.07.016  0.36
2004 Li Q, Esper RM, Loeb JA. Synergistic effects of neuregulin and agrin on muscle acetylcholine receptor expression. Molecular and Cellular Neurosciences. 26: 558-69. PMID 15276157 DOI: 10.1016/j.mcn.2004.04.009  0.36
2004 Yao B, Rakhade SN, Li Q, Ahmed S, Krauss R, Draghici S, Loeb JA. Accuracy of cDNA microarray methods to detect small gene expression changes induced by neuregulin on breast epithelial cells. Bmc Bioinformatics. 5: 99. PMID 15272935 DOI: 10.1186/1471-2105-5-99  0.36
2004 Esper RM, Loeb JA. Rapid axoglial signaling mediated by neuregulin and neurotrophic factors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6218-27. PMID 15240814 DOI: 10.1523/JNEUROSCI.1692-04.2004  0.36
2004 Nash TE, Del Brutto OH, Butman JA, Corona T, Delgado-Escueta A, Duron RM, Evans CA, Gilman RH, Gonzalez AE, Loeb JA, Medina MT, Pietsch-Escueta S, Pretell EJ, Takayanagui OM, Theodore W, et al. Calcific neurocysticercosis and epileptogenesis. Neurology. 62: 1934-8. PMID 15184592  0.36
2003 Loeb JA. Neuregulin: an activity-dependent synaptic modulator at the neuromuscular junction. Journal of Neurocytology. 32: 649-64. PMID 15034258 DOI: 10.1023/B:NEUR.0000020640.84708.35  0.36
2003 Li J, Loeb JA, Shy ME, Shah AK, Tselis AC, Kupski WJ, Lewis RA. Asymmetric flaccid paralysis: a neuromuscular presentation of West Nile virus infection. Annals of Neurology. 53: 703-10. PMID 12783415 DOI: 10.1002/ana.10575  0.36
2002 Loeb JA, Hmadcha A, Fischbach GD, Land SJ, Zakarian VL. Neuregulin expression at neuromuscular synapses is modulated by synaptic activity and neurotrophic factors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2206-14. PMID 11896160  0.36
2001 Li Q, Loeb JA. Neuregulin-heparan-sulfate proteoglycan interactions produce sustained erbB receptor activation required for the induction of acetylcholine receptors in muscle. The Journal of Biological Chemistry. 276: 38068-75. PMID 11502740 DOI: 10.1074/jbc.M104485200  0.36
1999 Ford BD, Loeb JA, Fischbach GD. Neuregulin stimulates DNA synthesis in embryonic chick heart cells. Developmental Biology. 214: 139-50. PMID 10491263 DOI: 10.1006/dbio.1999.9394  0.36
1999 Loeb JA, Khurana TS, Robbins JT, Yee AG, Fischbach GD. Expression patterns of transmembrane and released forms of neuregulin during spinal cord and neuromuscular synapse development. Development (Cambridge, England). 126: 781-91. PMID 9895325  0.36
1998 Loeb JA, Susanto ET, Fischbach GD. The neuregulin precursor proARIA is processed to ARIA after expression on the cell surface by a protein kinase C-enhanced mechanism. Molecular and Cellular Neurosciences. 11: 77-91. PMID 9608535 DOI: 10.1006/mcne.1998.0676  0.36
1998 Loeb JA. Functional improvement in a patient with cerebral calcinosis using a bisphosphonate. Movement Disorders : Official Journal of the Movement Disorder Society. 13: 345-9. PMID 9539353 DOI: 10.1002/mds.870130225  0.36
1998 Loeb JA. Features of Leao's spreading depression in patients with lesions near sensory cortex Journal of Epilepsy. 11: 110-115. DOI: 10.1016/S0896-6974(97)00136-9  0.36
1997 Loeb JA, Fischbach GD. Neurotrophic factors increase neuregulin expression in embryonic ventral spinal cord neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1416-24. PMID 9006983  0.36
1996 Rosen KM, Sandrock AW, Goodearl AD, Loeb JA, Fischbach GD. The role of neuregulin (ARIA) at the neuromuscular junction. Cold Spring Harbor Symposia On Quantitative Biology. 61: 427-34. PMID 9246471  0.36
1995 Loeb JA, Fischbach GD. ARIA can be released from extracellular matrix through cleavage of a heparin-binding domain. The Journal of Cell Biology. 130: 127-35. PMID 7540614 DOI: 10.1083/jcb.130.1.127  0.36
1989 Loeb JA, Herold KC, Barton KP, Robinson LE, Jaspan JB. Systematic approach to diagnosis and management of biphasic insulin allergy with local anti-inflammatory agents. Diabetes Care. 12: 421-3. PMID 2659301  0.36
1988 Loeb JA, Drickamer K. Conformational changes in the chicken receptor for endocytosis of glycoproteins. Modulation of ligand-binding activity by Ca2+ and pH. The Journal of Biological Chemistry. 263: 9752-60. PMID 3290213  0.36
1987 Loeb JA, Drickamer K. The chicken receptor for endocytosis of glycoproteins contains a cluster of N-acetylglucosamine-binding sites. The Journal of Biological Chemistry. 262: 3022-9. PMID 3818631  0.36
1987 Halberg DF, Wager RE, Farrell DC, Hildreth J, Quesenberry MS, Loeb JA, Holland EC, Drickamer K. Major and minor forms of the rat liver asialoglycoprotein receptor are independent galactose-binding proteins. Primary structure and glycosylation heterogeneity of minor receptor forms. The Journal of Biological Chemistry. 262: 9828-38. PMID 3597443  0.36
1983 Loeb J, Dawson G. High density lipoprotein exchange reactions. Molecular and Cellular Biochemistry. 52: 161-76. PMID 6410179 DOI: 10.1007/BF00224925  0.36
1982 Loeb JA, Dawson G. Reversible exchange of glycosphingolipids between human high and low density lipoproteins. The Journal of Biological Chemistry. 257: 11982-7. PMID 7118925  0.36
Show low-probability matches.