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Mark Stuart Forman, MD, Duke University 1995, PhD, Rockefeller University 1994 - Publications

Affiliations: 
Experimental Medicine Merck Pharmaceuticals, Lincoln, NJ, United States 
Area:
Molecular pathogeneis of neurodegenerative disease
Website:
http://www.med.upenn.edu/cndr/MarkFormanbio.shtml

64/122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Rabinovici GD, Carrillo MC, Forman M, DeSanti S, Miller DS, Kozauer N, Petersen RC, Randolph C, Knopman DS, Smith EE, Isaac M, Mattsson N, Bain LJ, Hendrix JA, Sims JR. Multiple comorbid neuropathologies in the setting of Alzheimer's disease neuropathology and implications for drug development. Alzheimer's & Dementia (New York, N. Y.). 3: 83-91. PMID 29067320 DOI: 10.1016/J.Trci.2016.09.002  0.35
2016 Scott JD, Li SW, Brunskill AP, Chen X, Cox K, Cumming JN, Forman M, Gilbert EJ, Hodgson RA, Hyde LA, Jiang Q, Iserloh U, Kazakevich I, Kuvelkar R, Mei H, et al. Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)-A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer's Disease. Journal of Medicinal Chemistry. 59: 10435-10450. PMID 27933948 DOI: 10.1021/Acs.Jmedchem.6B00307  0.357
2010 Hu WT, McMillan C, Libon D, Leight S, Forman M, Lee VM, Trojanowski JQ, Grossman M. Multimodal predictors for Alzheimer disease in nonfluent primary progressive aphasia. Neurology. 75: 595-602. PMID 20713948 DOI: 10.1212/Wnl.0B013E3181Ed9C52  0.748
2010 Ritson GP, Custer SK, Freibaum BD, Guinto JB, Geffel D, Moore J, Tang W, Winton MJ, Neumann M, Trojanowski JQ, Lee VM, Forman MS, Taylor JP. TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7729-39. PMID 20519548 DOI: 10.1523/Jneurosci.5894-09.2010  0.669
2009 Gitcho MA, Strider J, Carter D, Taylor-Reinwald L, Forman MS, Goate AM, Cairns NJ. VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death. The Journal of Biological Chemistry. 284: 12384-98. PMID 19237541 DOI: 10.1074/Jbc.M900992200  0.404
2009 Neumann M, Kwong LK, Lee EB, Kremmer E, Flatley A, Xu Y, Forman MS, Troost D, Kretzschmar HA, Trojanowski JQ, Lee VM. Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathologica. 117: 137-49. PMID 19125255 DOI: 10.1007/S00401-008-0477-9  0.755
2008 Weihl CC, Temiz P, Miller SE, Watts G, Smith C, Forman M, Hanson PI, Kimonis V, Pestronk A. TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 1186-9. PMID 18796596 DOI: 10.1136/Jnnp.2007.131334  0.304
2008 Uryu K, Nakashima-Yasuda H, Forman MS, Kwong LK, Clark CM, Grossman M, Miller BL, Kretzschmar HA, Lee VM, Trojanowski JQ, Neumann M. Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies. Journal of Neuropathology and Experimental Neurology. 67: 555-64. PMID 18520774 DOI: 10.1097/Nen.0B013E31817713B5  0.712
2008 Bian H, Van Swieten JC, Leight S, Massimo L, Wood E, Forman M, Moore P, de Koning I, Clark CM, Rosso S, Trojanowski J, Lee VM, Grossman M. CSF biomarkers in frontotemporal lobar degeneration with known pathology. Neurology. 70: 1827-35. PMID 18458217 DOI: 10.1212/01.Wnl.0000311445.21321.Fc  0.655
2008 Grossman M, Xie SX, Libon DJ, Wang X, Massimo L, Moore P, Vesely L, Berkowitz R, Chatterjee A, Coslett HB, Hurtig HI, Forman MS, Lee VM, Trojanowski JQ. Longitudinal decline in autopsy-defined frontotemporal lobar degeneration. Neurology. 70: 2036-45. PMID 18420483 DOI: 10.1212/01.Wnl.0000303816.25065.Bc  0.664
2008 Kimonis VE, Mehta SG, Fulchiero EC, Thomasova D, Pasquali M, Boycott K, Neilan EG, Kartashov A, Forman MS, Tucker S, Kimonis K, Mumm S, Whyte MP, Smith CD, Watts GD. Clinical studies in familial VCP myopathy associated with Paget disease of bone and frontotemporal dementia. American Journal of Medical Genetics. Part A. 146: 745-57. PMID 18260132 DOI: 10.1002/Ajmg.A.31862  0.419
2008 Xie SX, Forman MS, Farmer J, Moore P, Wang Y, Wang X, Clark CM, Coslett HB, Chatterjee A, Arnold SE, Rosen H, Karlawish JH, Van Deerlin VM, Lee VM, Trojanowski JQ, et al. Factors associated with survival probability in autopsy-proven frontotemporal lobar degeneration. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 126-9. PMID 17615171 DOI: 10.1136/Jnnp.2006.110288  0.692
2007 Rabinovici GD, Seeley WW, Kim EJ, Gorno-Tempini ML, Rascovsky K, Pagliaro TA, Allison SC, Halabi C, Kramer JH, Johnson JK, Weiner MW, Forman MS, Trojanowski JQ, Dearmond SJ, Miller BL, et al. Distinct MRI atrophy patterns in autopsy-proven Alzheimer's disease and frontotemporal lobar degeneration. American Journal of Alzheimer's Disease and Other Dementias. 22: 474-88. PMID 18166607 DOI: 10.1177/1533317507308779  0.471
2007 Grossman M, Libon DJ, Forman MS, Massimo L, Wood E, Moore P, Anderson C, Farmer J, Chatterjee A, Clark CM, Coslett HB, Hurtig HI, Lee VM, Trojanowski JQ. Distinct antemortem profiles in patients with pathologically defined frontotemporal dementia. Archives of Neurology. 64: 1601-9. PMID 17998442 DOI: 10.1001/Archneur.64.11.1601  0.711
2007 Forman MS, Trojanowski JQ, Lee VM. TDP-43: a novel neurodegenerative proteinopathy. Current Opinion in Neurobiology. 17: 548-55. PMID 17936612 DOI: 10.1016/J.Conb.2007.08.005  0.734
2007 Grossman M, Wood EM, Moore P, Neumann M, Kwong L, Forman MS, Clark CM, McCluskey LF, Miller BL, Lee VM, Trojanowski JQ. TDP-43 pathologic lesions and clinical phenotype in frontotemporal lobar degeneration with ubiquitin-positive inclusions. Archives of Neurology. 64: 1449-54. PMID 17923628 DOI: 10.1001/Archneur.64.10.1449  0.707
2007 Van Deerlin VM, Wood EM, Moore P, Yuan W, Forman MS, Clark CM, Neumann M, Kwong LK, Trojanowski JQ, Lee VM, Grossman M. Clinical, genetic, and pathologic characteristics of patients with frontotemporal dementia and progranulin mutations. Archives of Neurology. 64: 1148-53. PMID 17698705 DOI: 10.1001/Archneur.64.8.1148  0.682
2007 Cairns NJ, Neumann M, Bigio EH, Holm IE, Troost D, Hatanpaa KJ, Foong C, White CL, Schneider JA, Kretzschmar HA, Carter D, Taylor-Reinwald L, Paulsmeyer K, Strider J, Gitcho M, ... ... Forman MS, et al. TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. The American Journal of Pathology. 171: 227-40. PMID 17591968 DOI: 10.2353/Ajpath.2007.070182  0.706
2007 Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Annals of Neurology. 61: 427-34. PMID 17469116 DOI: 10.1002/Ana.21147  0.674
2007 Guinto JB, Ritson GP, Taylor JP, Forman MS. Valosin-containing protein and the pathogenesis of frontotemporal dementia associated with inclusion body myopathy. Acta Neuropathologica. 114: 55-61. PMID 17457594 DOI: 10.1007/S00401-007-0224-7  0.457
2007 Murray R, Neumann M, Forman MS, Farmer J, Massimo L, Rice A, Miller BL, Johnson JK, Clark CM, Hurtig HI, Gorno-Tempini ML, Lee VM, Trojanowski JQ, Grossman M. Cognitive and motor assessment in autopsy-proven corticobasal degeneration. Neurology. 68: 1274-83. PMID 17438218 DOI: 10.1212/01.Wnl.0000259519.78480.C3  0.647
2007 Forman MS, Mufson EJ, Leurgans S, Pratico D, Joyce S, Leight S, Lee VM, Trojanowski JQ. Cortical biochemistry in MCI and Alzheimer disease: lack of correlation with clinical diagnosis. Neurology. 68: 757-63. PMID 17339583 DOI: 10.1212/01.Wnl.0000256373.39415.B1  0.72
2007 Neumann M, Mackenzie IR, Cairns NJ, Boyer PJ, Markesbery WR, Smith CD, Taylor JP, Kretzschmar HA, Kimonis VE, Forman MS. TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations. Journal of Neuropathology and Experimental Neurology. 66: 152-7. PMID 17279000 DOI: 10.1096/Fasebj.21.5.A25  0.459
2007 Myers AJ, Pittman AM, Zhao AS, Rohrer K, Kaleem M, Marlowe L, Lees A, Leung D, McKeith IG, Perry RH, Morris CM, Trojanowski JQ, Clark C, Karlawish J, Arnold S, ... Forman MS, et al. The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts. Neurobiology of Disease. 25: 561-70. PMID 17174556 DOI: 10.1016/J.Nbd.2006.10.018  0.554
2007 Van Deerlin VM, Forman MS, Farmer JM, Grossman M, Joyce S, Crowe A, Trojanowski JQ, Lee VM, Chatterjee A. Biochemical and pathological characterization of frontotemporal dementia due to a Leu266Val mutation in microtubule-associated protein tau in an African American individual. Acta Neuropathologica. 113: 471-9. PMID 17072625 DOI: 10.1007/S00401-006-0155-8  0.73
2006 Sánchez-Valle R, Forman MS, Miller BL, Gorno-Tempini ML. From progressive nonfluent aphasia to corticobasal syndrome: a case report of corticobasal degeneration. Neurocase. 12: 355-9. PMID 17182400 DOI: 10.1080/13554790600977218  0.408
2006 Forman MS, Mackenzie IR, Cairns NJ, Swanson E, Boyer PJ, Drachman DA, Jhaveri BS, Karlawish JH, Pestronk A, Smith TW, Tu PH, Watts GD, Markesbery WR, Smith CD, Kimonis VE. Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations. Journal of Neuropathology and Experimental Neurology. 65: 571-81. PMID 16783167 DOI: 10.1097/00005072-200606000-00005  0.431
2006 Forman MS, Farmer J, Johnson JK, Clark CM, Arnold SE, Coslett HB, Chatterjee A, Hurtig HI, Karlawish JH, Rosen HJ, Van Deerlin V, Lee VM, Miller BL, Trojanowski JQ, Grossman M. Frontotemporal dementia: clinicopathological correlations. Annals of Neurology. 59: 952-62. PMID 16718704 DOI: 10.1002/Ana.20873  0.728
2006 Clark CM, Forman MS. Frontotemporal lobar degeneration with motor neuron disease: a clinical and pathological spectrum. Archives of Neurology. 63: 489-90. PMID 16606759 DOI: 10.1001/Archneur.63.4.489  0.386
2006 Dabir DV, Robinson MB, Swanson E, Zhang B, Trojanowski JQ, Lee VM, Forman MS. Impaired glutamate transport in a mouse model of tau pathology in astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 644-54. PMID 16407562 DOI: 10.1523/Jneurosci.3861-05.2006  0.821
2006 Golden J, Dobyns W, Forman M. Response [3] Journal of Neuropathology and Experimental Neurology. 65: 302-303. DOI: 10.1097/01.Jnen.0000223200.80447.9F  0.493
2006 Forman MS, Leurgans S, Pratico D, Joyce S, Leight S, Mufson EJ, Lee VM, Trojanowski JQ. P2-207: Cortical biochemical markers of mild cognitive impairment Alzheimer's & Dementia. 2: S296-S296. DOI: 10.1016/J.Jalz.2006.05.1046  0.461
2006 Forman MS, Dabir D, Robinson MB, Swanson E, Zhang B, Trojanowski JQ, Lee VM. O2-01-03: Impaired glutamate transport and excitotoxicity in a mouse model of tau pathology in astrocytes Alzheimer's & Dementia. 2: S30-S30. DOI: 10.1016/J.Jalz.2006.05.104  0.776
2005 Higuchi M, Zhang B, Forman MS, Yoshiyama Y, Trojanowski JQ, Lee VM. Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9434-43. PMID 16221853 DOI: 10.1523/Jneurosci.2691-05.2005  0.719
2005 Forman MS, Squier W, Dobyns WB, Golden JA. Genotypically defined lissencephalies show distinct pathologies. Journal of Neuropathology and Experimental Neurology. 64: 847-57. PMID 16215456 DOI: 10.1097/01.Jnen.0000182978.56612.41  0.628
2005 Roberson ED, Hesse JH, Rose KD, Slama H, Johnson JK, Yaffe K, Forman MS, Miller CA, Trojanowski JQ, Kramer JH, Miller BL. Frontotemporal dementia progresses to death faster than Alzheimer disease. Neurology. 65: 719-25. PMID 16157905 DOI: 10.1212/01.Wnl.0000173837.82820.9F  0.539
2005 Forman MS, Lee VM, Trojanowski JQ. Nosology of Parkinson's disease: looking for the way out of a quagmire. Neuron. 47: 479-82. PMID 16102530 DOI: 10.1016/J.Neuron.2005.07.021  0.667
2005 Johnson JK, Diehl J, Mendez MF, Neuhaus J, Shapira JS, Forman M, Chute DJ, Roberson ED, Pace-Savitsky C, Neumann M, Chow TW, Rosen HJ, Forstl H, Kurz A, Miller BL. Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Archives of Neurology. 62: 925-30. PMID 15956163 DOI: 10.1001/Archneur.62.6.925  0.428
2005 Mott RT, Dickson DW, Trojanowski JQ, Zhukareva V, Lee VM, Forman M, Van Deerlin V, Ervin JF, Wang DS, Schmechel DE, Hulette CM. Neuropathologic, biochemical, and molecular characterization of the frontotemporal dementias. Journal of Neuropathology and Experimental Neurology. 64: 420-8. PMID 15892300 DOI: 10.1093/Jnen/64.5.420  0.727
2005 Forman MS, Lal D, Zhang B, Dabir DV, Swanson E, Lee VM, Trojanowski JQ. Transgenic mouse model of tau pathology in astrocytes leading to nervous system degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3539-50. PMID 15814784 DOI: 10.1523/Jneurosci.0081-05.2005  0.821
2005 Easton RM, Cho H, Roovers K, Shineman DW, Mizrahi M, Forman MS, Lee VM, Szabolcs M, de Jong R, Oltersdorf T, Ludwig T, Efstratiadis A, Birnbaum MJ. Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Molecular and Cellular Biology. 25: 1869-78. PMID 15713641 DOI: 10.1128/Mcb.25.5.1869-1878.2005  0.729
2005 Liang TW, Forman MS, Duda JE, McCluskey L, Trojanowski JQ, Siderowf A. Multiple pathologies in a patient with a progressive neurodegenerative syndrome. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 252-5. PMID 15654043 DOI: 10.1136/jnnp.2004.039479  0.586
2005 Forman MS, Lee VMY, Trojanowski JQ. Frontotemporal dementia with parkinsonism linked to Chromosome 17 Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics. 494-511. DOI: 10.1017/CBO9780511544873.036  0.47
2004 Forman MS, Trojanowski JQ, Lee VM. Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs. Nature Medicine. 10: 1055-63. PMID 15459709 DOI: 10.1038/Nm1113  0.698
2004 Zhang B, Higuchi M, Yoshiyama Y, Ishihara T, Forman MS, Martinez D, Joyce S, Trojanowski JQ, Lee VM. Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4657-67. PMID 15140937 DOI: 10.1523/Jneurosci.0797-04.2004  0.738
2004 Chou KL, Forman MS, Trojanowski JQ, Hurtig HI, Baltuch GH. Subthalamic nucleus deep brain stimulation in a patient with levodopa-responsive multiple system atrophy. Case report. Journal of Neurosurgery. 100: 553-6. PMID 15035294 DOI: 10.3171/Jns.2004.100.3.0553  0.533
2004 Wilhelmsen KC, Forman MS, Rosen HJ, Alving LI, Goldman J, Feiger J, Lee JV, Segall SK, Kramer JH, Lomen-Hoerth C, Rankin KP, Johnson J, Feiler HS, Weiner MW, Lee VM, et al. 17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions. Archives of Neurology. 61: 398-406. PMID 15023818 DOI: 10.1001/Archneur.61.3.398  0.719
2004 Dabir DV, Trojanowski JQ, Richter-Landsberg C, Lee VM, Forman MS. Expression of the small heat-shock protein alphaB-crystallin in tauopathies with glial pathology. The American Journal of Pathology. 164: 155-66. PMID 14695329  0.822
2004 Skovronsky D, Judkins AR, Kung M, Forman M, Martinez D, Hou C, Zhuang Z, Kung HF. P3-079 Characterization of neurodegenerative disease radioligands by tissue microarray analysis Neurobiology of Aging. 25: S375-S376. DOI: 10.1016/S0197-4580(04)81231-4  0.764
2004 Forman MS, Lal D, Zhang B, Dabir D, Lee VM, Trojanowski JQ. O1-04-01 Transgenic mouse models of TAU pathology in astrocytes leading to nervous system degeneration Neurobiology of Aging. 25: S16. DOI: 10.1016/S0197-4580(04)80052-6  0.785
2003 Goldbaum O, Oppermann M, Handschuh M, Dabir D, Zhang B, Forman MS, Trojanowski JQ, Lee VM, Richter-Landsberg C. Proteasome inhibition stabilizes tau inclusions in oligodendroglial cells that occur after treatment with okadaic acid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8872-80. PMID 14523089 DOI: 10.1523/Jneurosci.23-26-08872.2003  0.8
2003 Counelis GJ, Simuni T, Forman MS, Jaggi JL, Trojanowski JQ, Baltuch GH. Bilateral subthalamic nucleus deep brain stimulation for advanced PD: correlation of intraoperative MER and postoperative MRI with neuropathological findings. Movement Disorders : Official Journal of the Movement Disorder Society. 18: 1062-5. PMID 14502679 DOI: 10.1002/Mds.10489  0.484
2003 Forman MS, Lee VM, Trojanowski JQ. 'Unfolding' pathways in neurodegenerative disease. Trends in Neurosciences. 26: 407-10. PMID 12900170 DOI: 10.1016/S0166-2236(03)00197-8  0.679
2003 Giasson BI, Forman MS, Higuchi M, Golbe LI, Graves CL, Kotzbauer PT, Trojanowski JQ, Lee VM. Initiation and synergistic fibrillization of tau and alpha-synuclein. Science (New York, N.Y.). 300: 636-40. PMID 12714745 DOI: 10.1126/Science.1082324  0.75
2002 Trojanowski JQ, Ishihara T, Higuchi M, Yoshiyama Y, Hong M, Zhang B, Forman MS, Zhukareva V, Lee VM. Amyotrophic lateral sclerosis/parkinsonism dementia complex: transgenic mice provide insights into mechanisms underlying a common tauopathy in an ethnic minority on Guam. Experimental Neurology. 176: 1-11. PMID 12093078 DOI: 10.1006/Exnr.2002.7940  0.716
2002 Forman MS, Zhukareva V, Bergeron C, Chin SS, Grossman M, Clark C, Lee VM, Trojanowski JQ. Signature tau neuropathology in gray and white matter of corticobasal degeneration. The American Journal of Pathology. 160: 2045-53. PMID 12057909 DOI: 10.1016/S0002-9440(10)61154-6  0.729
2002 Forman MS, Schmidt ML, Kasturi S, Perl DP, Lee VM, Trojanowski JQ. Tau and alpha-synuclein pathology in amygdala of Parkinsonism-dementia complex patients of Guam. The American Journal of Pathology. 160: 1725-31. PMID 12000724 DOI: 10.1016/S0002-9440(10)61119-4  0.735
2002 Judkins AR, Forman MS, Uryu K, Hinkle DA, Asbury AK, Lee VM, Trojanowski JQ. Co-occurrence of Parkinson's disease with progressive supranuclear palsy. Acta Neuropathologica. 103: 526-30. PMID 11935271 DOI: 10.1007/S00401-001-0483-7  0.742
2001 Giasson BI, Duda JE, Forman MS, Lee VM, Trojanowski JQ. Prominent perikaryal expression of alpha- and beta-synuclein in neurons of dorsal root ganglion and in medullary neurons. Experimental Neurology. 172: 354-62. PMID 11716559 DOI: 10.1006/Exnr.2001.7805  0.733
2001 Fung KM, Forman MS, Cucchiara B, ZuLinska E, Wallis-Crespo M, Lavi E. July 2000: A 70 year old with rigidity, decreased ocular movements, and dementia. Brain Pathology (Zurich, Switzerland). 11: 119-20, 125. PMID 11145197  0.636
2000 Forman MS, Lee VM, Trojanowski JQ. New insights into genetic and molecular mechanisms of brain degeneration in tauopathies. Journal of Chemical Neuroanatomy. 20: 225-44. PMID 11207421 DOI: 10.1016/S0891-0618(00)00100-9  0.669
1999 Abrahams JM, Forman MS, Lavi E, Goldberg H, Flamm ES. Hemangiopericytoma of the third ventricle. Case report. Journal of Neurosurgery. 90: 359-62. PMID 9950509 DOI: 10.3171/Jns.1999.90.2.0359  0.467
1997 Forman MS, Cook DG, Leight S, Doms RW, Lee VM. Differential effects of the swedish mutant amyloid precursor protein on beta-amyloid accumulation and secretion in neurons and nonneuronal cells. The Journal of Biological Chemistry. 272: 32247-53. PMID 9405428 DOI: 10.1074/Jbc.272.51.32247  0.331
1997 Schmidt ML, Lee Virginia MY, Forman M, Chiu TS, Trojanowski JQ. Monoclonal antibodies to a 100-kd protein reveal abundant Aβ-negative plaques throughout gray matter of Alzheimer's disease brains American Journal of Pathology. 151: 69-80. PMID 9212733  0.309
Low-probability matches (unlikely to be authored by this person)
2001 Robinson W, Galetta SL, McCluskey L, Forman MS, Balcer LJ. Retinal findings in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil). Survey of Ophthalmology. 45: 445-8. PMID 11274696 DOI: 10.1016/S0039-6257(00)00206-X  0.292
2017 Kalinina J, Cheon K, Stone J, Kennedy M, Forman M, Egan MF, Tanen MR, Winrow CJ, Savage MJ. ACUTE ADMINISTRATION OF A BACE INHIBITOR IN HEALTHY HUMANS RESULTS IN A SIGNIFICANT REDUCTION OF Aβ OLIGOMERS IN CEREBROSPINAL FLUID Alzheimer's & Dementia. 13: P574. DOI: 10.1016/J.Jalz.2017.07.192  0.27
2008 Gitcho MA, Strider J, Carter D, Taylor-Reinwald L, Forman MS, Morris JC, Goate AM, Cairns NJ. P2-185: FTLD-U–linked missense mutations in VCP/p97 alter localization of endogenous TDP-43 and induce cell death Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1259  0.268
1997 Cook DG, Forman MS, Sung JC, Leight S, Kolson DL, Iwatsubo T, Lee VM, Doms RW. Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells. Nature Medicine. 3: 1021-3. PMID 9288730 DOI: 10.1038/Nm0997-1021  0.262
2015 Lucey BP, Gonzales C, Das U, Li J, Siemers ER, Slemmon JR, Bateman RJ, Huang Y, Fox GB, Claassen JA, Slats D, Verbeek MM, Tong G, Soares H, Savage MJ, ... ... Forman M, et al. An integrated multi-study analysis of intra-subject variability in cerebrospinal fluid amyloid-β concentrations collected by lumbar puncture and indwelling lumbar catheter. Alzheimer's Research & Therapy. 7: 53. PMID 26225140 DOI: 10.1186/S13195-015-0136-Z  0.249
2016 Kennedy ME, Stamford AW, Chen X, Cox K, Cumming JN, Dockendorf MF, Egan M, Ereshefsky L, Hodgson RA, Hyde LA, Jhee S, Kleijn HJ, Kuvelkar R, Li W, Mattson BA, ... ... Forman MS, et al. The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer's disease patients. Science Translational Medicine. 8: 363ra150. PMID 27807285 DOI: 10.1126/scitranslmed.aad9704  0.248
1997 Li HL, Forman MS, Kurosaki T, Puré E. Syk is required for BCR-mediated activation of p90Rsk, but not p70S6k, via a mitogen-activated protein kinase-independent pathway in B cells. The Journal of Biological Chemistry. 272: 18200-8. PMID 9218456 DOI: 10.1074/Jbc.272.29.18200  0.243
2003 Cucchiara BL, Forman MS, McGarvey ML, Kasner SE, King D. Fatal subacute cytomegalovirus encephalitis associated with hypogammaglobulinemia and thymoma. Mayo Clinic Proceedings. 78: 223-7. PMID 12583534 DOI: 10.4065/78.2.223  0.241
2004 Forman MS. Genotype-phenotype correlations in FTDP-17: does form follow function? Experimental Neurology. 187: 229-34. PMID 15144848 DOI: 10.1016/J.Expneurol.2004.01.031  0.239
2012 Ma L, Dockendorf M, Krishna G, Kleijn H, Su J, Forman M, Stone J. Population pharmacokinetic modeling of the novel BACE inhibitor MK-8931 following single and multiple dose administration in healthy subjects Alzheimers & Dementia. 8: 187. DOI: 10.1016/J.Jalz.2012.05.508  0.193
2018 Lohith TG, Bennacef I, Vandenberghe R, Vandenbulcke M, Salinas-Valenzuela C, Declercq R, Reynders T, Telan-Choing F, Riffel K, Celen S, Serdons K, Bormans G, Tsai K, Walji A, Hostetler ED, ... ... Forman M, et al. First-in-human brain imaging of Alzheimer dementia patients and elderly controls with F-MK-6240, a PET tracer targeting neurofibrillary tangle pathology. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29880509 DOI: 10.2967/Jnumed.118.208215  0.191
1999 Hsu WC, Loevner LA, Forman MS, Thaler ER. Superficial siderosis of the CNS associated with multiple cavernous malformations. Ajnr. American Journal of Neuroradiology. 20: 1245-8. PMID 10472980  0.18
2018 Chris Min K, Dockendorf MF, Palcza J, Tseng J, Ma L, Stone JA, Kleijn HJ, Hodsman P, Masuo K, Tanen M, Troyer MD, van Vugt M, Forman MS. Pharmacokinetics and Pharmacodynamics of the BACE1 Inhibitor Verubecestat (MK-8931) in Healthy Japanese Adults: a Randomized, Placebo-Controlled Study. Clinical Pharmacology and Therapeutics. PMID 30347431 DOI: 10.1002/cpt.1258  0.173
2019 Forman M, Palcza J, Tseng J, Stone JA, Walker B, Swearingen D, Troyer MD, Dockendorf MF. Safety, Tolerability, and Pharmacokinetics of the β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor Verubecestat (MK-8931) in Healthy Elderly Male and Female Subjects. Clinical and Translational Science. PMID 31215755 DOI: 10.1111/cts.12645  0.134
2011 Sanabria-Bohorquez S, Hostetler E, Van Laere K, Koole M, Bormans G, Serdons K, de Hoon J, Vandenberghe R, Versijpt J, De Lepeleire I, Reynders T, Tamagnan G, Marek K, Seibyl J, Jennings D, ... ... Forman M, et al. P2-035: Preliminary evaluation of the amyloid PET Radioligand [18F]MK-3328 in Alzheimer's Disease patients Alzheimer's & Dementia. 7: S319-S319. DOI: 10.1016/J.Jalz.2011.05.925  0.122
2017 Gold L, Egan M, Forman M, Dam T, Zhang Y, Kost J, Michelson D. POTENTIAL THERAPEUTIC BENEFITS OF DECREASING Aβ PRODUCTION THROUGH BACE INHIBITION Innovation in Aging. 1: 349-350. DOI: 10.1093/GERONI/IGX004.1279  0.116
2010 Forman MS, Nishikubo JB, Han RK, Le A, Balashova NV, Kachlany SC. Gangliosides block Aggregatibacter Actinomycetemcomitans leukotoxin (LtxA)-mediated hemolysis. Toxins. 2: 2824-36. PMID 22069577 DOI: 10.3390/toxins2122824  0.098
2001 Jabs DA, Martin BK, Forman MS, Dunn JP, Davis JL, Weinberg DV, Biron KK, Baldanti F. Mutations conferring ganciclovir resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. The Journal of Infectious Diseases. 183: 333-337. PMID 11120934 DOI: 10.1086/317931  0.095
2003 Weinberg A, Jabs DA, Chou S, Martin BK, Lurain NS, Forman MS, Crumpacker C. Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. The Journal of Infectious Diseases. 187: 777-84. PMID 12599051 DOI: 10.1086/368385  0.094
2002 Hu H, Jabs DA, Forman MS, Martin BK, Dunn JP, Weinberg DV, Davis JL. Comparison of cytomegalovirus (CMV) UL97 gene sequences in the blood and vitreous of patients with acquired immunodeficiency syndrome and CMV retinitis. The Journal of Infectious Diseases. 185: 861-7. PMID 11920309 DOI: 10.1086/339603  0.093
2003 Jabs DA, Martin BK, Forman MS, Hubbard L, Dunn JP, Kempen JH, Davis JL, Weinberg DV. Cytomegalovirus resistance to ganciclovir and clinical outcomes of patients with cytomegalovirus retinitis. American Journal of Ophthalmology. 135: 26-34. PMID 12504693 DOI: 10.1016/S0002-9394(02)01759-2  0.093
1985 Forman MS, Nakamura M, Mimori T, Gelpi C, Hardin JA. Detection of antibodies to small nuclear ribonucleoproteins and small cytoplasmic ribonucleoproteins using unlabeled cell extracts. Arthritis and Rheumatism. 28: 1356-61. PMID 2935157 DOI: 10.1002/art.1780281207  0.092
2015 Forman MS, Chuang SK, August M. The Accuracy of Clinical Diagnosis of Oral Lesions and Patient-Specific Risk Factors that Affect Diagnosis. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. PMID 25981860 DOI: 10.1016/j.joms.2015.04.026  0.091
2015 Forman MS, Chuang SK, August M. The Accuracy of Clinical Diagnosis of Oral Lesions and Patient-Specific Risk Factors that Affect Diagnosis Journal of Oral and Maxillofacial Surgery. DOI: 10.1016/j.joms.2015.04.026  0.091
1994 Brozna JP, Forman M, Carson SD. Staurosporine blocks down-regulation of monocyte-associated tissue factor Blood Coagulation and Fibrinolysis. 5: 929-938. PMID 7534487  0.086
2006 Jabs DA, Martin BK, Ricks MO, Forman MS. Detection of ganciclovir resistance in patients with AIDS and cytomegalovirus retinitis: correlation of genotypic methods with viral phenotype and clinical outcome. The Journal of Infectious Diseases. 193: 1728-37. PMID 16703517 DOI: 10.1086/504270  0.083
1995 Dunn JP, MacCumber MW, Forman MS, Charache P, Apuzzo L, Jabs DA. Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir. American Journal of Ophthalmology. 119: 587-96. PMID 7733184 DOI: 10.1016/S0002-9394(14)70217-X  0.079
2001 Jabs DA, Martin BK, Forman MS, Dunn JP, Davis JL, Weinberg DV, Biron KK, Baldanti F, Hu H. Longitudinal observations on mutations conferring ganciclovir resistance in patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis: The Cytomegalovirus and Viral Resistance Study Group Report Number 8. American Journal of Ophthalmology. 132: 700-10. PMID 11704031 DOI: 10.1016/S0002-9394(01)01161-8  0.075
2000 Boockvar JA, Shafa R, Forman MS, O'Rourke DM. Symptomatic lateral ventricular ependymal cysts: criteria for distinguishing these rare cysts from other symptomatic cysts of the ventricles: case report. Neurosurgery. 46: 1229-32; discussion . PMID 10807256  0.069
1997 Enger C, Jabs DA, Dunn JP, Forman MS, Bressler NM, Margolick JB, Charache P. Viral resistance and CMV retinitis: design and methods of a prospective study. CRVR Research Groups. Cytomegalovirus Retinitis Viral Resistance Research Group. Ophthalmic Epidemiology. 4: 41-8. PMID 9145415 DOI: 10.3109/09286589709058060  0.068
1986 Bender BS, Bennett R, Laughon BE, Greenough WB, Gaydos C, Sears SD, Forman MS, Bartlett JG. Is Clostridium difficile endemic in chronic-care facilities? Lancet. 2: 11-3. PMID 2873315 DOI: 10.1016/S0140-6736(86)92559-6  0.059
2001 Abrahams JM, Forman MS, Grady MS, Diamond SL. Delivery of human vascular endothelial growth factor with platinum coils enhances wall thickening and coil impregnation in a rat aneurysm model. Ajnr. American Journal of Neuroradiology. 22: 1410-7. PMID 11498439  0.055
2020 Gibson C, Hartmann G, Ma B, Chain A, Smith S, Forman M, Datta S, Bateman T, Li Y, Khalilieh S. P213 - A priori prediction of CYP3A victim drug-drug interaction of MK-1 and diltiazem using physiologically-based pharmacokinetic modeling (PBPK): qualification using clinical data Drug Metabolism and Pharmacokinetics. 35: S87. DOI: 10.1016/J.Dmpk.2020.04.214  0.049
2005 Jabs DA, Martin BK, Forman MS, Ricks MO. Cytomegalovirus (CMV) blood DNA load, CMV retinitis progression, and occurrence of resistant CMV in patients with CMV retinitis. The Journal of Infectious Diseases. 192: 640-9. PMID 16028133 DOI: 10.1086/432012  0.049
2012 Forman MS, Advani S, Newman C, Gaydos CA, Milstone AM, Valsamakis A. Diagnostic performance of two highly multiplexed respiratory virus assays in a pediatric cohort. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 55: 168-72. PMID 22832060 DOI: 10.1016/j.jcv.2012.06.019  0.048
2010 Jabs DA, Martin BK, Forman MS. Mortality associated with resistant cytomegalovirus among patients with cytomegalovirus retinitis and AIDS. Ophthalmology. 117: 128-132.e2. PMID 19818505 DOI: 10.1016/j.ophtha.2009.06.016  0.048
2001 Abrahams JM, Forman MS, Grady MS, Diamond SL. Biodegradable polyglycolide endovascular coils promote wall thickening and drug delivery in a rat aneurysm model. Neurosurgery. 49: 1187-93; discussion . PMID 11846912 DOI: 10.1097/00006123-200111000-00030  0.046
2010 Hart DE, Forman M, Veale AG. Effect of tubing condensate on non-invasive positive pressure ventilators tested under simulated clinical conditions. Sleep & Breathing = Schlaf & Atmung. 15: 535-41. PMID 20669050 DOI: 10.1007/s11325-010-0397-5  0.044
1991 Forman MS, Puré E. T-independent and T-dependent B lymphoblasts: helper T cells prime for interleukin 2-induced growth and secretion of immunoglobulins that utilize downstream heavy chains. The Journal of Experimental Medicine. 173: 687-97. PMID 1825505 DOI: 10.1084/JEM.173.3.687  0.043
1979 Forman MS, Adams EW, Vanderpool EA, Turner W. Induction of acid-stable canine interferon in vivo and in vitro. American Journal of Veterinary Research. 40: 1440-2. PMID 43104  0.041
2011 Forman M. The Politics of Inheritance in Romans The Politics of Inheritance in Romans. 1-268. DOI: 10.1017/CBO9780511975141  0.04
2015 Greer AE, Forman MS, Valsamakis A. Comparison of BKV quantification using a single automated nucleic acid extraction platform and 3 real-time PCR assays. Diagnostic Microbiology and Infectious Disease. 82: 297-302. PMID 25971156 DOI: 10.1016/J.Diagmicrobio.2015.04.006  0.038
2007 Martin BK, Ricks MO, Forman MS, Jabs DA. Change over time in incidence of ganciclovir resistance in patients with cytomegalovirus retinitis. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 44: 1001-8. PMID 17342657 DOI: 10.1086/512368  0.036
1993 Forman MS, Charache P. Ethical considerations of molecular genetic testing for infectious agents Clinical Chemistry. 39: 716.  0.027
2003 Knepp JH, Geahr MA, Forman MS, Valsamakis A. Comparison of automated and manual nucleic acid extraction methods for detection of enterovirus RNA. Journal of Clinical Microbiology. 41: 3532-6. PMID 12904351 DOI: 10.1128/JCM.41.8.3532-3536.2003  0.027
2011 Murthy S, Hayward GS, Wheelan S, Forman MS, Ahn JH, Pass RF, Arav-Boger R. Detection of a single identical cytomegalovirus (CMV) strain in recently seroconverted young women. Plos One. 6: e15949. PMID 21264339 DOI: 10.1371/Journal.Pone.0015949  0.026
1992 Forman MS, Merz CS, Charache P. Detection of herpes simplex virus by a nonradiometric spin-amplified in situ hybridization assay. Journal of Clinical Microbiology. 30: 581-4. PMID 1372619  0.023
2008 Hayden RT, Hokanson KM, Pounds SB, Bankowski MJ, Belzer SW, Carr J, Diorio D, Forman MS, Joshi Y, Hillyard D, Hodinka RL, Nikiforova MN, Romain CA, Stevenson J, Valsamakis A, et al. Multicenter comparison of different real-time PCR assays for quantitative detection of Epstein-Barr virus. Journal of Clinical Microbiology. 46: 157-63. PMID 17989187 DOI: 10.1128/JCM.01252-07  0.021
1999 Harmenberg J, Brytting M, Jabs DA, Forman MS, Enger CL. Limitations of cytomegalovirus testing [1] (multiple letters) Antimicrobial Agents and Chemotherapy. 43: 1528-1529. PMID 10383372  0.015
2021 Forman M, Kouassi A, Brandt T, Barsky L, Zamora C, Dekarske D. Palatability and Swallowability of Pimavanserin When Mixed with Selected Food Vehicles: An Exploratory Open-Label Crossover Study. Geriatrics (Basel, Switzerland). 6. PMID 34203662 DOI: 10.3390/geriatrics6020061  0.014
2008 Sarrazin C, Dragan A, Gärtner BC, Forman MS, Traver S, Zeuzem S, Valsamakis A. Evaluation of an automated, highly sensitive, real-time PCR-based assay (COBAS Ampliprep/COBAS TaqMan) for quantification of HCV RNA. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 43: 162-8. PMID 18692434 DOI: 10.1016/j.jcv.2008.06.013  0.014
2004 Forman MS, Valsamakis A. Increased sensitivity of the Roche COBAS AMPLICOR HCV test, version 2.0, using modified extraction techniques. The Journal of Molecular Diagnostics : Jmd. 6: 225-30. PMID 15269299 DOI: 10.1016/S1525-1578(10)60514-4  0.013
2001 Nowak-Wegrzyn A, Phipatanakul W, Winkelstein JA, Forman MS, Lederman HM. Successful treatment of enterovirus infection with the use of pleconaril in 2 infants with severe combined immunodeficiency. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 32: E13-4. PMID 11112666 DOI: 10.1086/317523  0.012
2016 Gotter AL, Forman MS, Harrell CM, Stevens J, Svetnik V, Yee KL, Li X, Roecker AJ, Fox SV, Tannenbaum PL, Garson SL, Lepeleire ID, Calder N, Rosen L, Struyk A, et al. Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man. Scientific Reports. 6: 27147. PMID 27256922 DOI: 10.1038/Srep27147  0.01
2008 Forman MS, Valsamakis A. Performance characteristics of a quantitative hepatitis C virus RNA assay using COBAS AmpliPrep total nucleic acid isolation and COBAS taqman hepatitis C virus analyte-specific reagent. The Journal of Molecular Diagnostics : Jmd. 10: 147-53. PMID 18276771 DOI: 10.2353/jmoldx.2008.070108  0.01
2004 Forman MS, Valsamakis A. Verification of an assay for quantification of hepatitis C virus RNA by use of an analyte-specific reagent and two different extraction methods. Journal of Clinical Microbiology. 42: 3581-8. PMID 15297501 DOI: 10.1128/JCM.42.8.3581-3588.2004  0.01
1993 Threlkeld AB, Froggatt JW, Schein OD, Forman MS. Efficacy of a disinfectant wipe method for the removal of adenovirus 8 from tonometer tips. Ophthalmology. 100: 1841-5. PMID 8259284  0.01
1989 Barnes SD, Leclair JM, Forman MS, Townsend TR, Laughlin GM, Charache P. Comparison of nasal brush and nasopharyngeal aspirate techniques in obtaining specimens for detection of respiratory syncytial viral antigen by immunofluorescence. The Pediatric Infectious Disease Journal. 8: 598-601. PMID 2677955  0.01
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