Year |
Citation |
Score |
2017 |
Owen DR, Fan J, Campioli E, Venugopal S, Midzak A, Daly E, Harlay A, Issop L, Libri V, Kalogiannopoulou D, Oliver E, Gallego-Colon E, Colasanti A, Huson L, Rabiner I, et al. TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis. The Biochemical Journal. PMID 29074640 DOI: 10.1042/Bcj20170648 |
0.404 |
|
2016 |
Midzak A, Papadopoulos V. Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein Assemblies. Frontiers in Endocrinology. 7: 106. PMID 27524977 DOI: 10.3389/Fendo.2016.00106 |
0.423 |
|
2015 |
Midzak A, Zirkin B, Papadopoulos V. Translocator protein: pharmacology and steroidogenesis. Biochemical Society Transactions. 43: 572-8. PMID 26551695 DOI: 10.1042/Bst20150061 |
0.58 |
|
2015 |
Fan J, Campioli E, Midzak A, Culty M, Papadopoulos V. Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation. Proceedings of the National Academy of Sciences of the United States of America. 112: 7261-6. PMID 26039990 DOI: 10.1073/Pnas.1502670112 |
0.305 |
|
2015 |
Midzak A, Denora N, Laquintana V, Cutrignelli A, Lopedota A, Franco M, Altomare CD, Papadopoulos V. 2-Phenylimidazo[1,2-a]pyridine-containing ligands of the 18-kDa translocator protein (TSPO) behave as agonists and antagonists of steroidogenesis in a mouse leydig tumor cell line. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 76: 231-7. PMID 26002041 DOI: 10.1016/J.Ejps.2015.05.021 |
0.352 |
|
2015 |
Midzak AS, Akula N, Rone MB, Papadopoulos V. Computational modeling and biological validation of novel non-steroidal ligands for the cholesterol recognition/interaction amino acid consensus (CRAC) motif of the mitochondrial translocator protein (TSPO). Pharmacological Research. 99: 393-403. PMID 25936508 DOI: 10.1016/J.Phrs.2015.03.023 |
0.414 |
|
2015 |
Papadopoulos V, Aghazadeh Y, Fan J, Campioli E, Zirkin B, Midzak A. Translocator protein-mediated pharmacology of cholesterol transport and steroidogenesis. Molecular and Cellular Endocrinology. 408: 90-8. PMID 25818881 DOI: 10.1016/J.Mce.2015.03.014 |
0.559 |
|
2014 |
Rone MB, Midzak AS, Martinez-Arguelles DB, Fan J, Ye X, Blonder J, Papadopoulos V. Steroidogenesis in MA-10 mouse Leydig cells is altered via fatty acid import into the mitochondria. Biology of Reproduction. 91: 96. PMID 25210128 DOI: 10.1095/Biolreprod.114.121434 |
0.449 |
|
2014 |
Midzak A, Papadopoulos V. Binding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterols. Traffic (Copenhagen, Denmark). 15: 895-914. PMID 24890942 DOI: 10.1111/Tra.12177 |
0.372 |
|
2013 |
Chung JY, Chen H, Midzak A, Burnett AL, Papadopoulos V, Zirkin BR. Drug ligand-induced activation of translocator protein (TSPO) stimulates steroid production by aged Brown Norway rat leydig cells Endocrinology. 154: 2156-2165. PMID 23525219 DOI: 10.1210/En.2012-2226 |
0.584 |
|
2012 |
Midzak A, Rammouz G, Papadopoulos V. Structure-activity relationship (SAR) analysis of a family of steroids acutely controlling steroidogenesis. Steroids. 77: 1327-34. PMID 22986075 DOI: 10.1016/J.Steroids.2012.08.019 |
0.408 |
|
2012 |
Rone MB, Midzak AS, Issop L, Rammouz G, Jagannathan S, Fan J, Ye X, Blonder J, Veenstra T, Papadopoulos V. Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones. Molecular Endocrinology (Baltimore, Md.). 26: 1868-82. PMID 22973050 DOI: 10.1210/Me.2012-1159 |
0.42 |
|
2012 |
Akula N, Midzak A, Lecanu L, Papadopoulos V. Identification of small-molecule inhibitors of the steroidogenic acute regulatory protein (STARD1) by structure-based design. Bioorganic & Medicinal Chemistry Letters. 22: 4139-43. PMID 22575868 DOI: 10.1016/J.Bmcl.2012.04.058 |
0.328 |
|
2011 |
Midzak AS, Chen H, Aon MA, Papadopoulos V, Zirkin BR. ATP synthesis, mitochondrial function, and steroid biosynthesis in rodent primary and tumor Leydig cells. Biology of Reproduction. 84: 976-85. PMID 21228212 DOI: 10.1095/Biolreprod.110.087460 |
0.571 |
|
2011 |
Midzak A, Akula N, Lecanu L, Papadopoulos V. Novel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis. The Journal of Biological Chemistry. 286: 9875-87. PMID 21209087 DOI: 10.1074/Jbc.M110.203216 |
0.456 |
|
2011 |
Midzak A, Rone M, Aghazadeh Y, Culty M, Papadopoulos V. Mitochondrial protein import and the genesis of steroidogenic mitochondria. Molecular and Cellular Endocrinology. 336: 70-9. PMID 21147195 DOI: 10.1016/J.Mce.2010.12.007 |
0.416 |
|
2009 |
Midzak AS, Chen H, Papadopoulos V, Zirkin BR. Leydig cell aging and the mechanisms of reduced testosterone synthesis. Molecular and Cellular Endocrinology. 299: 23-31. PMID 18761053 DOI: 10.1016/J.Mce.2008.07.016 |
0.551 |
|
2008 |
Midzak A, Zirkin BR. Metabolic Control of Steroidogenesis and Implications for Aging in the Brown Norway Rat Leydig Cell. Biology of Reproduction. 78: 82-82. DOI: 10.1093/Biolreprod/78.S1.82 |
0.527 |
|
2008 |
Chen H, Zhou L, Midzak AS, Beattie MC, Liu J, Zirkin BR. Effect of Glutathione Depletion on Susceptibility of MA-10 Leydig Cell Steroidogenesis to Oxidative Stress. Biology of Reproduction. 78: 151-151. DOI: 10.1093/Biolreprod/78.S1.151A |
0.571 |
|
2007 |
Midzak AS, Liu J, Zirkin BR, Chen H. Effect of myxothiazol on Leydig cell steroidogenesis: inhibition of luteinizing hormone-mediated testosterone synthesis but stimulation of basal steroidogenesis. Endocrinology. 148: 2583-90. PMID 17332065 DOI: 10.1210/En.2006-1488 |
0.564 |
|
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