Martha C. Bohn - Publications

Pediatrics: Neurobiology Northwestern University, Evanston, IL 
Parkinson's Disease

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Jara JH, Stanford MJ, Zhu Y, Tu M, Hauswirth WW, Bohn MC, DeVries SH, Özdinler PH. Healthy and diseased corticospinal motor neurons are selectively transduced upon direct AAV2-2 injection into the motor cortex. Gene Therapy. PMID 26704722 DOI: 10.1038/Gt.2015.112  0.388
2015 Jara JH, Genç B, Cox GA, Bohn MC, Roos RP, Macklis JD, Ulup?nar E, Özdinler PH. Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function. Cerebral Cortex (New York, N.Y. : 1991). PMID 25596590 DOI: 10.1093/Cercor/Bhu318  0.363
2014 Khodr CE, Becerra A, Han Y, Bohn MC. Targeting alpha-synuclein with a microRNA-embedded silencing vector in the rat substantia nigra: positive and negative effects. Brain Research. 1550: 47-60. PMID 24463035 DOI: 10.1016/J.Brainres.2014.01.010  0.442
2014 Malchenko S, Xie J, de Fatima Bonaldo M, Vanin EF, Bhattacharyya BJ, Belmadani A, Xi G, Galat V, Goossens W, Seftor RE, Tomita T, Crispino J, Miller RJ, Bohn MC, Hendrix MJ, et al. Onset of rosette formation during spontaneous neural differentiation of hESC and hiPSC colonies. Gene. 534: 400-7. PMID 23954875 DOI: 10.1016/J.Gene.2013.07.101  0.402
2013 Rodríguez SS, Schwerdt JI, Barbeito CG, Flamini MA, Han Y, Bohn MC, Goya RG. Hypothalamic IGF-I gene therapy prolongs estrous cyclicity and protects ovarian structure in middle-aged female rats. Endocrinology. 154: 2166-73. PMID 23584855 DOI: 10.1210/En.2013-1069  0.394
2013 Glavaski-Joksimovic A, Bohn MC. Mesenchymal stem cells and neuroregeneration in Parkinson's disease. Experimental Neurology. 247: 25-38. PMID 23542820 DOI: 10.1016/J.Expneurol.2013.03.016  0.694
2012 Jara JH, Villa SR, Khan NA, Bohn MC, Ozdinler PH. AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS. Neurobiology of Disease. 47: 174-83. PMID 22521461 DOI: 10.1016/J.Nbd.2012.03.036  0.359
2012 Khodr CE, Pedapati J, Han Y, Bohn MC. Inclusion of a portion of the native SNCA 3'UTR reduces toxicity of human S129A SNCA on striatal-projecting dopamine neurons in rat substantia nigra. Developmental Neurobiology. 72: 906-17. PMID 22021082 DOI: 10.1002/Dneu.20989  0.532
2011 Degeorge ML, Marlowe D, Werner E, Soderstrom KE, Stock M, Mueller A, Bohn MC, Kozlowski DA. Combining glial cell line-derived neurotrophic factor gene delivery (AdGDNF) with L-arginine decreases contusion size but not behavioral deficits after traumatic brain injury. Brain Research. 1403: 45-56. PMID 21672665 DOI: 10.1016/J.Brainres.2011.05.058  0.651
2011 Khodr CE, Sapru MK, Pedapati J, Han Y, West NC, Kells AP, Bankiewicz KS, Bohn MC. An α-synuclein AAV gene silencing vector ameliorates a behavioral deficit in a rat model of Parkinson's disease, but displays toxicity in dopamine neurons. Brain Research. 1395: 94-107. PMID 21565333 DOI: 10.1016/J.Brainres.2011.04.036  0.554
2011 Han Y, Khodr CE, Sapru MK, Pedapati J, Bohn MC. A microRNA embedded AAV α-synuclein gene silencing vector for dopaminergic neurons. Brain Research. 1386: 15-24. PMID 21338582 DOI: 10.1016/J.Brainres.2011.02.041  0.513
2010 Glavaski-Joksimovic A, Virag T, Mangatu TA, McGrogan M, Wang XS, Bohn MC. Glial cell line-derived neurotrophic factor-secreting genetically modified human bone marrow-derived mesenchymal stem cells promote recovery in a rat model of Parkinson's disease. Journal of Neuroscience Research. 88: 2669-81. PMID 20544825 DOI: 10.1002/Jnr.22435  0.736
2010 Minnich JE, Mann SL, Stock M, Stolzenbach KA, Mortell BM, Soderstrom KE, Bohn MC, Kozlowski DA. Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects cortical neurons from dying following a traumatic brain injury. Restorative Neurology and Neuroscience. 28: 293-309. PMID 20479525 DOI: 10.3233/Rnn-2010-0528  0.671
2009 Glavaski-Joksimovic A, Virag T, Chang QA, West NC, Mangatu TA, McGrogan MP, Dugich-Djordjevic M, Bohn MC. Reversal of dopaminergic degeneration in a parkinsonian rat following micrografting of human bone marrow-derived neural progenitors. Cell Transplantation. 18: 801-14. PMID 19796495 DOI: 10.3727/096368909X470801  0.732
2008 Bolliet C, Bohn MC, Spector M. Non-viral delivery of the gene for glial cell line-derived neurotrophic factor to mesenchymal stem cells in vitro via a collagen scaffold. Tissue Engineering. Part C, Methods. 14: 207-19. PMID 18721070 DOI: 10.1089/Ten.Tec.2008.0168  0.442
2008 Ebert AD, Hann HJ, Bohn MC. Progressive degeneration of dopamine neurons in 6-hydroxydopamine rat model of Parkinson's disease does not involve activation of caspase-9 and caspase-3. Journal of Neuroscience Research. 86: 317-25. PMID 17787016 DOI: 10.1002/Jnr.21480  0.699
2006 Rick CE, Ebert A, Virag T, Bohn MC, Surmeier DJ. Differentiated dopaminergic MN9D cells only partially recapitulate the electrophysiological properties of midbrain dopaminergic neurons. Developmental Neuroscience. 28: 528-37. PMID 17028430 DOI: 10.1159/000095115  0.685
2006 Hadaczek P, Yamashita Y, Mirek H, Tamas L, Bohn MC, Noble C, Park JW, Bankiewicz K. The "perivascular pump" driven by arterial pulsation is a powerful mechanism for the distribution of therapeutic molecules within the brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 69-78. PMID 16650807 DOI: 10.1016/J.Ymthe.2006.02.018  0.332
2006 Sapru MK, Yates JW, Hogan S, Jiang L, Halter J, Bohn MC. Silencing of human alpha-synuclein in vitro and in rat brain using lentiviral-mediated RNAi. Experimental Neurology. 198: 382-90. PMID 16455076 DOI: 10.1016/J.Expneurol.2005.12.024  0.344
2006 Zhao P, Awosika W, Wu N, Macias F, Cepeda C, Levine M, Vellis Jd, Rick CE, Ebert A, Virag T, Bohn MC, Surmeier DJ, Espinosa-Jeffrey A, Lv X, Wang N, et al. Contents Vol. 28, 2006 Developmental Neuroscience. 28: 555-557. DOI: 10.1159/000096120  0.482
2006 Zhao P, Awosika W, Wu N, Macias F, Cepeda C, Levine M, Vellis Jd, Rick CE, Ebert A, Virag T, Bohn MC, Surmeier DJ, Espinosa-Jeffrey A, Lv X, Wang N, et al. Subject Index Vol. 28, 2006 Developmental Neuroscience. 28: 553-554. DOI: 10.1159/000096119  0.482
2005 Smith AD, Kozlowski DA, Bohn MC, Zigmond MJ. Effect of AdGDNF on dopaminergic neurotransmission in the striatum of 6-OHDA-treated rats. Experimental Neurology. 193: 420-6. PMID 15869944 DOI: 10.1016/J.Expneurol.2005.01.010  0.702
2005 Ebert AD, Chen F, He X, Cryns VL, Bohn MC. A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not in vivo. Experimental Neurology. 191: S80-94. PMID 15629764 DOI: 10.1016/J.Expneurol.2004.08.024  0.691
2004 Kozlowski DA, Miljan EA, Bremer EG, Harrod CG, Gerin C, Connor B, George D, Larson B, Bohn MC. Quantitative analyses of GFRalpha-1 and GFRalpha-2 mRNAs and tyrosine hydroxylase protein in the nigrostriatal system reveal bilateral compensatory changes following unilateral 6-OHDA lesions in the rat. Brain Research. 1016: 170-81. PMID 15246853 DOI: 10.1016/J.Brainres.2004.05.003  0.744
2004 Jiang L, Rampalli S, George D, Press C, Bremer EG, O'Gorman MR, Bohn MC. Tight regulation from a single tet-off rAAV vector as demonstrated by flow cytometry and quantitative, real-time PCR. Gene Therapy. 11: 1057-67. PMID 15152187 DOI: 10.1038/Sj.Gt.3302245  0.419
2001 Connor B, Kozlowski DA, Unnerstall JR, Elsworth JD, Tillerson JL, Schallert T, Bohn MC. Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration. Experimental Neurology. 169: 83-95. PMID 11312561 DOI: 10.1006/Exnr.2001.7638  0.792
2001 Kozlowski DA, Bremer E, Redmond DE, George D, Larson B, Bohn MC. Quantitative analysis of transgene protein, mRNA, and vector DNA following injection of an adenoviral vector harboring glial cell line-derived neurotrophic factor into the primate caudate nucleus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 256-61. PMID 11237683 DOI: 10.1006/Mthe.2000.0256  0.617
2000 Derby ML, Giuliano R, Figlewicz DA, Bohn MC. GDNF is trophic for mouse motoneurons that express a mutant superoxide dismutase (SOD-1) gene. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 1: 113-22. PMID 11467048 DOI: 10.1080/14660820050515412  0.328
2000 Bohn MC, Connor B, Kozlowski DA, Mohajeri MH. Gene transfer for neuroprotection in animal models of Parkinson's disease and amyotrophic lateral sclerosis. Novartis Foundation Symposium. 231: 70-89; discussion 89. PMID 11131547 DOI: 10.1002/0470870834.Ch5  0.771
2000 Kozlowski DA, Connor B, Tillerson JL, Schallert T, Bohn MC. Delivery of a GDNF gene into the substantia nigra after a progressive 6-OHDA lesion maintains functional nigrostriatal connections. Experimental Neurology. 166: 1-15. PMID 11031079 DOI: 10.1006/Exnr.2000.7463  0.788
2000 Bohn MC, Kozlowski DA, Connor B. Glial cell line-derived neurotrophic factor (GDNF) as a defensive molecule for neurodegenerative disease: a tribute to the studies of antonia vernadakis on neuronal-glial interactions. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 18: 679-84. PMID 10978846 DOI: 10.1016/S0736-5748(00)00036-8  0.768
1999 Connor B, Kozlowski DA, Schallert T, Tillerson JL, Davidson BL, Bohn MC. Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged Parkinsonian rat. Gene Therapy. 6: 1936-51. PMID 10637445 DOI: 10.1038/Sj.Gt.3301033  0.793
1999 Lawrence MS, Foellmer HG, Elsworth JD, Kim JH, Leranth C, Kozlowski DA, Bothwell AL, Davidson BL, Bohn MC, Redmond DE. Inflammatory responses and their impact on beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus. Gene Therapy. 6: 1368-79. PMID 10467361 DOI: 10.1038/Sj.Gt.3300958  0.607
1999 Mohajeri MH, Figlewicz DA, Bohn MC. Intramuscular grafts of myoblasts genetically modified to secrete glial cell line-derived neurotrophic factor prevent motoneuron loss and disease progression in a mouse model of familial amyotrophic lateral sclerosis. Human Gene Therapy. 10: 1853-66. PMID 10446925 DOI: 10.1089/10430349950017536  0.331
1999 Bohn MC, Choi-Lundberg DL, Davidson BL, Leranth C, Kozlowski DA, Smith JC, O'Banion MK, Redmond DE. Adenovirus-mediated transgene expression in nonhuman primate brain. Human Gene Therapy. 10: 1175-84. PMID 10340549 DOI: 10.1089/10430349950018166  0.632
1998 Choi-Lundberg DL, Lin Q, Schallert T, Crippens D, Davidson BL, Chang YN, Chiang YL, Qian J, Bardwaj L, Bohn MC. Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor. Experimental Neurology. 154: 261-75. PMID 9878166 DOI: 10.1006/Exnr.1998.6887  0.565
1995 Yoshimoto Y, Lin Q, Collier TJ, Frim DM, Breakefield XO, Bohn MC. Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson's disease. Brain Research. 691: 25-36. PMID 8590062 DOI: 10.1016/0006-8993(95)00596-I  0.403
1994 Cunningham LA, Short MP, Breakefield XO, Bohn MC. Nerve growth factor released by transgenic astrocytes enhances the function of adrenal chromaffin cell grafts in a rat model of Parkinson's disease. Brain Research. 658: 219-31. PMID 7834345  0.377
1991 Cunningham LA, Hansen JT, Short MP, Bohn MC. The use of genetically altered astrocytes to provide nerve growth factor to adrenal chromaffin cells grafted into the striatum. Brain Research. 561: 192-202. PMID 1686984 DOI: 10.1016/0006-8993(91)91595-R  0.364
1991 Engele J, Schubert D, Bohn MC. Conditioned media derived from glial cell lines promote survival and differentiation of dopaminergic neurons in vitro: role of mesencephalic glia. Journal of Neuroscience Research. 30: 359-71. PMID 1686785 DOI: 10.1002/jnr.490300212  0.36
1991 Cunningham LA, Short MP, Vielkind U, Breakefield XO, Bohn MC. Survival and differentiation within the adult mouse striatum of grafted rat pheochromocytoma cells (PC12) genetically modified to express recombinant beta-NGF. Experimental Neurology. 112: 174-82. PMID 1674694 DOI: 10.1016/0014-4886(91)90067-M  0.321
1988 Uht RM, McKelvy JF, Harrison RW, Bohn MC. Demonstration of glucocorticoid receptor-like immunoreactivity in glucocorticoid-sensitive vasopressin and corticotropin-releasing factor neurons in the hypothalamic paraventricular nucleus. Journal of Neuroscience Research. 19: 405-11, 468-9. PMID 3260289 DOI: 10.1002/Jnr.490190404  0.305
1987 Bohn MC, Cupit L, Marciano F, Gash DM. Adrenal medulla grafts enhance recovery of striatal dopaminergic fibers. Science (New York, N.Y.). 237: 913-6. PMID 2887034  0.325
1986 Bohn MC, Goldstein M, Black IB. Expression and development of phenylethanolamine N-methyltransferase (PNMT) in rat brain stem: studies with glucocorticoids. Developmental Biology. 114: 180-93. PMID 3514317 DOI: 10.1016/0012-1606(86)90394-5  0.323
1981 Black IB, Bohn MC, Jonakait GM, Kessler JA. Transmitter phenotypic expression in the embryo. Ciba Foundation Symposium. 83: 177-93. PMID 6117422 DOI: 10.1002/9780470720653.ch9  0.305
1981 Bohn MC, Goldstein M, Black IB. Role of glucocorticoids in expression of the adrenergic phenotype in rat embryonic adrenal gland. Developmental Biology. 82: 1-10. PMID 6112174 DOI: 10.1016/0012-1606(81)90423-1  0.376
1980 Bohn MC, Lauder JM. Cerebellar granule cell genesis in the hydrocortisone-treated rats. Developmental Neuroscience. 3: 81-9. PMID 7418632 DOI: 10.1159/000112380  0.38
1978 Bohn MC, Lauder JM. The Effects of Neonatal Hydrocortisone on Rat Cerebellar Development Developmental Neuroscience. 1: 250-266. DOI: 10.1159/000112579  0.331
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