| Year |
Citation |
Score |
| 2018 |
Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X. Crk proteins transduce FGF signaling to promote lens fiber cell elongation. Elife. 7. PMID 29360039 DOI: 10.7554/Elife.32586 |
0.435 |
|
| 2016 |
Sana ME, Quilliam LA, Spitaleri A, Pezzoli L, Marchetti D, Lodrini C, Candiago E, Lincesso AR, Ferrazzi P, Iascone M. A Novel HRAS Mutation Independently Contributes to Left Ventricular Hypertrophy in a Family with a Known MYH7 Mutation. Plos One. 11: e0168501. PMID 28002430 DOI: 10.1371/Journal.Pone.0168501 |
0.319 |
|
| 2015 |
Chrzanowska-Wodnicka M, White GC, Quilliam LA, Whitehead KJ. Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature. Plos One. 10: e0145689. PMID 26714318 DOI: 10.1371/Journal.Pone.0145689 |
0.318 |
|
| 2015 |
Birukova AA, Meng F, Tian Y, Meliton A, Sarich N, Quilliam LA, Birukov KG. Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1. Biochimica Et Biophysica Acta. 1852: 778-91. PMID 25545047 DOI: 10.1016/J.Bbadis.2014.12.016 |
0.308 |
|
| 2014 |
Sayyah J, Bartakova A, Nogal N, Quilliam LA, Stupack DG, Brown JH. The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth. The Journal of Biological Chemistry. 289: 17689-98. PMID 24790104 DOI: 10.1074/Jbc.M113.536227 |
0.529 |
|
| 2013 |
Wittchen ES, Nishimura E, McCloskey M, Wang H, Quilliam LA, Chrzanowska-Wodnicka M, Hartnett ME. Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo. Plos One. 8: e73070. PMID 24039860 DOI: 10.1371/Journal.Pone.0073070 |
0.388 |
|
| 2013 |
Babcock JT, Nguyen HB, He Y, Hendricks JW, Wek RC, Quilliam LA. Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response. The Journal of Biological Chemistry. 288: 15687-98. PMID 23612979 DOI: 10.1074/Jbc.M112.431056 |
0.767 |
|
| 2013 |
Schmid MC, Franco I, Kang SW, Hirsch E, Quilliam LA, Varner JA. PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth. Plos One. 8: e60226. PMID 23565202 DOI: 10.1371/Journal.Pone.0060226 |
0.445 |
|
| 2013 |
Nguyen HB, Babcock JT, Wells CD, Quilliam LA. LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap. Oncogene. 32: 4100-9. PMID 23027127 DOI: 10.1038/Onc.2012.431 |
0.786 |
|
| 2012 |
Crotzer VL, Matute JD, Arias AA, Zhao H, Quilliam LA, Dinauer MC, Blum JS. Cutting edge: NADPH oxidase modulates MHC class II antigen presentation by B cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 3800-4. PMID 22984083 DOI: 10.4049/Jimmunol.1103080 |
0.303 |
|
| 2012 |
Siroky BJ, Yin H, Babcock JT, Lu L, Hellmann AR, Dixon BP, Quilliam LA, Bissler JJ. Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress. American Journal of Physiology. Renal Physiology. 303: F831-44. PMID 22791333 DOI: 10.1152/Ajprenal.00441.2011 |
0.758 |
|
| 2012 |
Jeyaraj SC, Unger NT, Eid AH, Mitra S, Paul El-Dahdah N, Quilliam LA, Flavahan NA, Chotani MA. Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 303: C499-511. PMID 22621783 DOI: 10.1152/Ajpcell.00461.2011 |
0.428 |
|
| 2012 |
Castro AF, Campos T, Babcock JT, Armijo ME, Martínez-Conde A, Pincheira R, Quilliam LA. M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells. Journal of Cellular Biochemistry. 113: 1253-64. PMID 22121046 DOI: 10.1002/Jcb.23458 |
0.761 |
|
| 2012 |
Nguyen HB, Babcock JT, Wells CD, Quilliam LA. Abstract LB-29: LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-29 |
0.785 |
|
| 2012 |
Babcock JT, Nguen HB, He Y, Wek RC, Quilliam LA. Abstract LB-247: mTORC1 enhances bortezomib-induced death in TSC-null cells by a c-MYC-dependent induction of the unfolded protein response Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-247 |
0.779 |
|
| 2011 |
Bai Y, Luo Y, Liu S, Zhang L, Shen K, Dong Y, Walls CD, Quilliam LA, Wells CD, Cao Y, Zhang ZY. PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein. The Journal of Biological Chemistry. 286: 42316-24. PMID 22009749 DOI: 10.1074/Jbc.M111.286302 |
0.394 |
|
| 2011 |
Kepner EM, Yoder SM, Oh E, Kalwat MA, Wang Z, Quilliam LA, Thurmond DC. Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 301: E1072-80. PMID 21828338 DOI: 10.1152/Ajpendo.00312.2011 |
0.374 |
|
| 2011 |
Babcock JT, Quilliam LA. Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin. Current Drug Targets. 12: 1223-31. PMID 21561413 DOI: 10.2174/138945011795906589 |
0.759 |
|
| 2010 |
Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam LA, Chrzanowska-Wodnicka M, White GC, Malarkannan S. Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. The Journal of Experimental Medicine. 207: 1923-38. PMID 20733035 DOI: 10.1084/Jem.20100040 |
0.328 |
|
| 2010 |
Panchatcharam M, Miriyala S, Yang F, Leitges M, Chrzanowska-Wodnicka M, Quilliam LA, Anaya P, Morris AJ, Smyth SS. Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling. The International Journal of Biochemistry & Cell Biology. 42: 965-74. PMID 20184965 DOI: 10.1016/J.Biocel.2010.02.009 |
0.367 |
|
| 2008 |
Asuri S, Yan J, Paranavitana NC, Quilliam LA. E-cadherin dis-engagement activates the Rap1 GTPase. Journal of Cellular Biochemistry. 105: 1027-37. PMID 18767072 DOI: 10.1002/Jcb.21902 |
0.74 |
|
| 2008 |
Yan J, Li F, Ingram DA, Quilliam LA. Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions. Molecular and Cellular Biology. 28: 5803-10. PMID 18625726 DOI: 10.1128/Mcb.00393-08 |
0.649 |
|
| 2007 |
Li Y, Yan J, De P, Chang HC, Yamauchi A, Christopherson KW, Paranavitana NC, Peng X, Kim C, Munugalavadla V, Munugulavadla V, Kapur R, Chen H, Shou W, Stone JC, ... ... Quilliam LA, et al. Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. Journal of Immunology (Baltimore, Md. : 1950). 179: 8322-31. PMID 18056377 DOI: 10.4049/Jimmunol.179.12.8322 |
0.606 |
|
| 2007 |
Quilliam LA. New insights into the mechanisms of SOS activation. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe67. PMID 18042941 DOI: 10.1126/Stke.4142007Pe67 |
0.429 |
|
| 2007 |
Hong J, Doebele RC, Lingen MW, Quilliam LA, Tang WJ, Rosner MR. Anthrax edema toxin inhibits endothelial cell chemotaxis via Epac and Rap1. The Journal of Biological Chemistry. 282: 19781-7. PMID 17491018 DOI: 10.1074/Jbc.M700128200 |
0.311 |
|
| 2006 |
Quilliam LA. Specificity and expression of RalGPS as RalGEFs. Methods in Enzymology. 407: 108-14. PMID 16757318 DOI: 10.1016/S0076-6879(05)07010-2 |
0.37 |
|
| 2006 |
Felekkis K, Quilliam LA, Lerner A. Characterization of AND-34 function and signaling. Methods in Enzymology. 407: 55-63. PMID 16757314 DOI: 10.1016/S0076-6879(05)07006-0 |
0.393 |
|
| 2006 |
Li Y, Asuri S, Rebhun JF, Castro AF, Paranavitana NC, Quilliam LA. The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane. The Journal of Biological Chemistry. 281: 2506-14. PMID 16316996 DOI: 10.1074/Jbc.M508165200 |
0.743 |
|
| 2005 |
Castro AF, Rebhun JF, Quilliam LA. Measuring Ras-family GTP levels in vivo--running hot and cold. Methods (San Diego, Calif.). 37: 190-6. PMID 16289967 DOI: 10.1016/J.Ymeth.2005.05.015 |
0.398 |
|
| 2005 |
Felekkis KN, Narsimhan RP, Near R, Castro AF, Zheng Y, Quilliam LA, Lerner A. AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner. Molecular Cancer Research : McR. 3: 32-41. PMID 15671247 |
0.409 |
|
| 2004 |
Arthur WT, Quilliam LA, Cooper JA. Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. The Journal of Cell Biology. 167: 111-22. PMID 15479739 DOI: 10.1083/Jcb.200404068 |
0.497 |
|
| 2003 |
Castro AF, Rebhun JF, Clark GJ, Quilliam LA. Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner. The Journal of Biological Chemistry. 278: 32493-6. PMID 12842888 DOI: 10.1074/Jbc.C300226200 |
0.493 |
|
| 2003 |
Zheng Y, Quilliam LA. Activation of the Ras superfamily of small GTPases. Workshop on exchange factors. Embo Reports. 4: 463-8. PMID 12717452 DOI: 10.1038/Sj.Embor.Embor831 |
0.457 |
|
| 2002 |
Gu Y, Byrne MC, Paranavitana NC, Aronow B, Siefring JE, D'Souza M, Horton HF, Quilliam LA, Williams DA. Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells. Molecular and Cellular Biology. 22: 7645-57. PMID 12370311 DOI: 10.1128/Mcb.22.21.7645-7657.2002 |
0.471 |
|
| 2002 |
Quilliam LA, Rebhun JF, Castro AF. A growing family of guanine nucleotide exchange factors is responsible for activation of Ras-family GTPases. Progress in Nucleic Acid Research and Molecular Biology. 71: 391-444. PMID 12102558 DOI: 10.1016/S0079-6603(02)71047-7 |
0.439 |
|
| 2002 |
Reuther GW, Lambert QT, Rebhun JF, Caligiuri MA, Quilliam LA, Der CJ. RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia. The Journal of Biological Chemistry. 277: 30508-14. PMID 11880369 DOI: 10.1074/Jbc.M111330200 |
0.377 |
|
| 2002 |
Mei FC, Qiao J, Tsygankova OM, Meinkoth JL, Quilliam LA, Cheng X. Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation. The Journal of Biological Chemistry. 277: 11497-504. PMID 11801596 DOI: 10.1074/Jbc.M110856200 |
0.358 |
|
| 2001 |
Zong H, Kaibuchi K, Quilliam LA. The insert region of RhoA is essential for Rho kinase activation and cellular transformation. Molecular and Cellular Biology. 21: 5287-98. PMID 11463812 DOI: 10.1128/Mcb.21.16.5287-5298.2001 |
0.443 |
|
| 2001 |
Quilliam LA, Rebhun JF, Zong H, Castro AF. Analyses of M-Ras/R-Ras3 signaling and biology. Methods in Enzymology. 333: 187-202. PMID 11400336 DOI: 10.1016/S0076-6879(01)33056-2 |
0.385 |
|
| 2001 |
Tsygankova OM, Saavedra A, Rebhun JF, Quilliam LA, Meinkoth JL. Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A. Molecular and Cellular Biology. 21: 1921-9. PMID 11238928 DOI: 10.1128/Mcb.21.6.1921-1929.2001 |
0.486 |
|
| 2000 |
Rebhun JF, Castro AF, Quilliam LA. Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction. The Journal of Biological Chemistry. 275: 34901-8. PMID 10934204 DOI: 10.1074/Jbc.M005327200 |
0.422 |
|
| 2000 |
Rebhun JF, Chen H, Quilliam LA. Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral. The Journal of Biological Chemistry. 275: 13406-10. PMID 10747847 DOI: 10.1074/Jbc.C000085200 |
0.4 |
|
| 2000 |
Sood R, Porter AC, Ma K, Quilliam LA, Wek RC. Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress. The Biochemical Journal. 346: 281-93. PMID 10677345 DOI: 10.1042/0264-6021:3460281 |
0.393 |
|
| 1999 |
Quilliam LA, Castro AF, Rogers-Graham KS, Martin CB, Der CJ, Bi C. M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6. The Journal of Biological Chemistry. 274: 23850-7. PMID 10446149 DOI: 10.1074/Jbc.274.34.23850 |
0.325 |
|
| 1999 |
Braverman LE, Quilliam LA. Identification of Grb4/Nckβ, a Src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck Journal of Biological Chemistry. 274: 5542-5549. PMID 10026169 DOI: 10.1074/Jbc.274.9.5542 |
0.403 |
|
| 1999 |
Zong H, Raman N, Mickelson-Young LA, Atkinson SJ, Quilliam LA. Loop 6 of RhoA confers specificity for effector binding, stress fiber formation, and cellular transformation Journal of Biological Chemistry. 274: 4551-4560. PMID 9988689 DOI: 10.1074/Jbc.274.8.4551 |
0.399 |
|
| 1997 |
Lander HM, Hajjar DP, Hempstead BL, Mirza UA, Chait BT, Campbell S, Quilliam LA. A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction. The Journal of Biological Chemistry. 272: 4323-6. PMID 9020151 DOI: 10.1074/Jbc.272.7.4323 |
0.386 |
|
| 1997 |
Huff SY, Quilliam LA, Cox AD, Der CJ. R-Ras is regulated by activators and effectors distinct from those that control Ras function Oncogene. 14: 133-143. PMID 9010215 DOI: 10.1038/Sj.Onc.1200815 |
0.392 |
|
| 1996 |
Quilliam LA, Lambert QT, Mickelson-Young LA, Westwick JK, Sparks AB, Kay BK, Jenkins NA, Gilbert DJ, Copeland NG, Der CJ. Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling. The Journal of Biological Chemistry. 271: 28772-6. PMID 8910519 DOI: 10.1074/Jbc.271.46.28772 |
0.397 |
|
| 1996 |
Bokoch GM, Wang Y, Bohl BP, Sells MA, Quilliam LA, Knaus UG. Interaction of the Nck adapter protein with p21-activated kinase (PAK1) Journal of Biological Chemistry. 271: 25746-25749. PMID 8824201 DOI: 10.1074/Jbc.271.42.25746 |
0.378 |
|
| 1996 |
Lander HM, Milbank AJ, Tauras JM, Hajjar DP, Hempstead BL, Schwartz GD, Kraemer RT, Mirza UA, Chait BT, Burk SC, Quilliam LA. Redox regulation of cell signalling. Nature. 381: 380-1. PMID 8632794 DOI: 10.1038/381380A0 |
0.414 |
|
| 1996 |
Quilliam LA, Hisaka MM, Zhong S, Lowry A, Mosteller RD, Han J, Drugan JK, Broek D, Campbell SL, Der CJ. Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors. The Journal of Biological Chemistry. 271: 11076-82. PMID 8626650 DOI: 10.1074/Jbc.271.19.11076 |
0.391 |
|
| 1996 |
Song KS, Li S, Okamoto T, Quilliam LA, Sargiacomo M, Lisanti MP. Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains: Detergent-free purification of caveolae membranes Journal of Biological Chemistry. 271: 9690-9697. PMID 8621645 DOI: 10.1074/Jbc.271.16.9690 |
0.375 |
|
| 1996 |
Fridell YWC, Jin Y, Quilliam LA, Burchert A, Mccloskey P, Spizz G, Varnum B, Der C, Liu ET. Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase Molecular and Cellular Biology. 16: 135-145. PMID 8524290 DOI: 10.1128/Mcb.16.1.135 |
0.419 |
|
| 1995 |
Overbeck AF, Brtva TR, Cox AD, Graham SM, Huff SY, Khosravi-Far R, Quilliam LA, Solski PA, Der CJ. Guanine nucleotide exchange factors: activators of Ras superfamily proteins. Molecular Reproduction and Development. 42: 468-76. PMID 8607978 DOI: 10.1002/Mrd.1080420415 |
0.312 |
|
| 1995 |
Quilliam LA, Khosravi-Far R, Huff SY, Der CJ. Guanine nucleotide exchange factors: Activators of the Ras superfamily of proteins Bioessays. 17: 395-404. PMID 7786285 DOI: 10.1002/Bies.950170507 |
0.324 |
|
| 1994 |
Quilliam LA, Huff SY, Rabun KM, Wei W, Park W, Broek D, Der CJ. Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity. Proceedings of the National Academy of Sciences of the United States of America. 91: 8512-6. PMID 8078913 DOI: 10.1073/Pnas.91.18.8512 |
0.334 |
|
| 1994 |
Maly FE, Quilliam LA, Dorseuil O, Der CJ, Bokoch GM. Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes Journal of Biological Chemistry. 269: 18743-18746. PMID 8034626 |
0.315 |
|
| 1994 |
Scheele JS, Pilz RB, Quilliam LA, Boss GR. Identification of a ras-related protein in murine erythroleukemia cells that is a cAMP-dependent protein kinase substrate and is phosphorylated during chemically induced differentiation Journal of Biological Chemistry. 269: 18599-18606. PMID 8034608 |
0.34 |
|
| 1993 |
Clark GJ, Quilliam LA, Hisaka MM, Der CJ. Differential antagonism of Ras biological activity by catalytic and Src homology domains of Ras GTPase activation protein Proceedings of the National Academy of Sciences of the United States of America. 90: 4887-4891. PMID 8506332 DOI: 10.1073/Pnas.90.11.4887 |
0.314 |
|
| 1993 |
Pendergast AM, Quilliam LA, Cripe LD, Bassing CH, Dai Z, Li N, Batzer A, Rabun KM, Der CJ, Schlessinger J. BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein. Cell. 75: 175-85. PMID 8402896 |
0.35 |
|
| 1991 |
Buss JE, Quilliam LA, Kato K, Casey PJ, Solski PA, Wong G, Clark R, McCormick F, Bokoch GM, Der CJ. The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein. Molecular and Cellular Biology. 11: 1523-30. PMID 1899909 DOI: 10.1128/Mcb.11.3.1523 |
0.319 |
|
| 1990 |
Quilliam LA, Der CJ, Brown JH. GTP-binding protein-stimulated phospholipase C and phospholipase D activities in ras-transformed NIH 3T3 fibroblasts Second Messengers and Phosphoproteins. 13: 59-67. PMID 2149569 |
0.333 |
|
| 1988 |
Brown JH, Orellana SA, Buss JE, Quilliam LA. Regulation of phosphoinositide hydrolysis by GTP-binding proteins, phorbol esters and botulinum toxin type D Advances in Experimental Medicine and Biology. 236: 229-237. PMID 2853564 DOI: 10.1007/978-1-4757-5971-6_18 |
0.366 |
|
| 1988 |
Quilliam LA, Brown JH, Buss JE. A 22 kDa ras-related G-protein is the substrate for an ADP-ribosyltransferase from Clostridium botulinum Febs Letters. 238: 22-26. PMID 2844595 DOI: 10.1016/0014-5793(88)80217-5 |
0.358 |
|
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