Year |
Citation |
Score |
2022 |
Peçanha FLM, Jaafar R, Werneck-de-Castro JP, Apostolopolou CC, Bhushan A, Bernal-Mizrachi E. The Transcription Factor YY1 is Essential for Normal DNA Repair and Cell Cycle in Human and Mouse β-cells. Diabetes. PMID 35594378 DOI: 10.2337/db21-0908 |
0.376 |
|
2019 |
Thompson PJ, Shah A, Apostolopolou H, Bhushan A. BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes. International Journal of Molecular Sciences. 20. PMID 31561444 DOI: 10.3390/Ijms20194776 |
0.496 |
|
2019 |
Jaafar R, Tran S, Shah A, Sun G, Valdearcos M, Marchetti P, Masini M, Swisa A, Giacometti S, Bernal-Mizrachi E, Matveyenko A, Hebrok M, Dor Y, Rutter GA, Koliwad SK, ... Bhushan A, et al. mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes. The Journal of Clinical Investigation. 130. PMID 31265435 DOI: 10.1172/Jci127021 |
0.432 |
|
2019 |
Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R. The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function. Diabetes. PMID 31201281 DOI: 10.2337/Db19-0349 |
0.498 |
|
2019 |
Nair GG, Liu JS, Russ HA, Tran S, Saxton MS, Chen R, Juang C, Li ML, Nguyen VQ, Giacometti S, Puri S, Xing Y, Wang Y, Szot GL, Oberholzer J, ... Bhushan A, et al. Author Correction: Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells. Nature Cell Biology. PMID 30914825 DOI: 10.1038/S41556-019-0316-3 |
0.352 |
|
2019 |
Thompson PJ, Shah A, Ntranos V, Van Gool F, Atkinson M, Bhushan A. Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes. Cell Metabolism. PMID 30799288 DOI: 10.1016/J.Cmet.2019.01.021 |
0.468 |
|
2019 |
Nair GG, Liu JS, Russ HA, Tran S, Saxton MS, Chen R, Juang C, Li ML, Nguyen VQ, Giacometti S, Puri S, Xing Y, Wang Y, Szot GL, Oberholzer J, ... Bhushan A, et al. Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells. Nature Cell Biology. 21: 263-274. PMID 30710150 DOI: 10.1038/S41556-018-0271-4 |
0.457 |
|
2018 |
Cyphert HA, Walker EM, Hang Y, Dhawan S, Haliyur R, Bonatakis L, Avrahami D, Brissova M, Kaestner KH, Bhushan A, Powers AC, Stein R. "Examining How the MAFB Transcription Factor Affects Islet β Cell Function Postnatally". Diabetes. PMID 30425060 DOI: 10.2337/Db18-0903 |
0.411 |
|
2017 |
Tschen SI, Zeng C, Field L, Dhawan S, Bhushan A, Georgia S. Cyclin D2 is sufficient to drive beta cell self-renewal and regeneration. Cell Cycle (Georgetown, Tex.). 0. PMID 28763258 DOI: 10.1080/15384101.2017.1319999 |
0.458 |
|
2016 |
Thompson P, Bhushan A. β Cells led astray by transcription factors and the company they keep. The Journal of Clinical Investigation. PMID 27941244 DOI: 10.1172/Jci91304 |
0.467 |
|
2016 |
Dhawan S, Dirice E, Kulkarni RN, Bhushan A. Inhibition of TGF-beta signaling promotes human pancreatic beta cell replication. Diabetes. PMID 26936960 DOI: 10.2337/Db15-1331 |
0.403 |
|
2015 |
Dhawan S, Tschen SI, Zeng C, Guo T, Hebrok M, Matveyenko A, Bhushan A. DNA methylation directs functional maturation of pancreatic β cells. The Journal of Clinical Investigation. PMID 26098213 DOI: 10.1172/Jci79956 |
0.413 |
|
2015 |
Stewart AF, Hussain MA, García-Ocaña A, Vasavada RC, Bhushan A, Bernal-Mizrachi E, Kulkarni RN. Human β-cell proliferation and intracellular signaling: part 3. Diabetes. 64: 1872-85. PMID 25999530 DOI: 10.2337/Db14-1843 |
0.422 |
|
2013 |
Zhou JX, Dhawan S, Fu H, Snyder E, Bottino R, Kundu S, Kim SK, Bhushan A. Combined modulation of polycomb and trithorax genes rejuvenates β cell replication. The Journal of Clinical Investigation. 123: 4849-58. PMID 24216481 DOI: 10.1172/Jci69468 |
0.413 |
|
2013 |
Kartikasari AE, Zhou JX, Kanji MS, Chan DN, Sinha A, Grapin-Botton A, Magnuson MA, Lowry WE, Bhushan A. The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation. The Embo Journal. 32: 1393-408. PMID 23584530 DOI: 10.1038/Emboj.2013.78 |
0.664 |
|
2013 |
Georgia S, Kanji M, Bhushan A. DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis. Genes & Development. 27: 372-7. PMID 23431054 DOI: 10.1101/Gad.207001.112 |
0.669 |
|
2013 |
Kanji MS, Martin MG, Bhushan A. Dicer1 is required to repress neuronal fate during endocrine cell maturation. Diabetes. 62: 1602-11. PMID 23382448 DOI: 10.2337/Db12-0841 |
0.665 |
|
2011 |
Papizan JB, Singer RA, Tschen SI, Dhawan S, Friel JM, Hipkens SB, Magnuson MA, Bhushan A, Sussel L. Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming. Genes & Development. 25: 2291-305. PMID 22056672 DOI: 10.1101/Gad.173039.111 |
0.424 |
|
2011 |
Tschen SI, Georgia S, Dhawan S, Bhushan A. Skp2 is required for incretin hormone-mediated β-cell proliferation. Molecular Endocrinology (Baltimore, Md.). 25: 2134-43. PMID 21980072 DOI: 10.1210/Me.2011-1119 |
0.435 |
|
2011 |
Dhawan S, Georgia S, Tschen SI, Fan G, Bhushan A. Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx. Developmental Cell. 20: 419-29. PMID 21497756 DOI: 10.1016/J.Devcel.2011.03.012 |
0.412 |
|
2010 |
Georgia S, Bhushan A. Pregnancy hormones boost beta cells via serotonin. Nature Medicine. 16: 756-7. PMID 20613752 DOI: 10.1038/Nm0710-756 |
0.397 |
|
2010 |
Matveyenko AV, Georgia S, Bhushan A, Butler PC. Inconsistent formation and nonfunction of insulin-positive cells from pancreatic endoderm derived from human embryonic stem cells in athymic nude rats. American Journal of Physiology. Endocrinology and Metabolism. 299: E713-20. PMID 20587750 DOI: 10.1152/Ajpendo.00279.2010 |
0.371 |
|
2010 |
Georgia S, Hinault C, Kawamori D, Hu J, Meyer J, Kanji M, Bhushan A, Kulkarni RN. Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents. Diabetes. 59: 987-96. PMID 20103709 DOI: 10.2337/Db09-0838 |
0.675 |
|
2009 |
Dhawan S, Tschen SI, Bhushan A. Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation. Genes & Development. 23: 906-11. PMID 19390085 DOI: 10.1101/Gad.1742609 |
0.467 |
|
2009 |
Tschen SI, Dhawan S, Gurlo T, Bhushan A. Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice. Diabetes. 58: 1312-20. PMID 19228811 DOI: 10.2337/Db08-1651 |
0.429 |
|
2009 |
Schulthess FT, Katz S, Ardestani A, Kawahira H, Georgia S, Bosco D, Bhushan A, Maedler K. Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. Plos One. 4: e4394. PMID 19197367 DOI: 10.1371/Journal.Pone.0004394 |
0.427 |
|
2008 |
Meier JJ, Butler AE, Saisho Y, Monchamp T, Galasso R, Bhushan A, Rizza RA, Butler PC. Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans. Diabetes. 57: 1584-94. PMID 18334605 DOI: 10.2337/Db07-1369 |
0.417 |
|
2007 |
Dhawan S, Georgia S, Bhushan A. Formation and regeneration of the endocrine pancreas. Current Opinion in Cell Biology. 19: 634-45. PMID 18061427 DOI: 10.1016/J.Ceb.2007.09.015 |
0.538 |
|
2007 |
Butler PC, Meier JJ, Butler AE, Bhushan A. The replication of beta cells in normal physiology, in disease and for therapy. Nature Clinical Practice. Endocrinology & Metabolism. 3: 758-68. PMID 17955017 DOI: 10.1038/Ncpendmet0647 |
0.469 |
|
2007 |
Zhong L, Georgia S, Tschen SI, Nakayama K, Nakayama K, Bhushan A. Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells. The Journal of Clinical Investigation. 117: 2869-76. PMID 17823659 DOI: 10.1172/Jci32198 |
0.502 |
|
2007 |
Butler AE, Huang A, Rao PN, Bhushan A, Hogan WJ, Rizza RA, Butler PC. Hematopoietic stem cells derived from adult donors are not a source of pancreatic beta-cells in adult nondiabetic humans. Diabetes. 56: 1810-6. PMID 17456852 DOI: 10.2337/Db06-1385 |
0.495 |
|
2006 |
Georgia S, Bhushan A. p27 Regulates the transition of beta-cells from quiescence to proliferation. Diabetes. 55: 2950-6. PMID 17065330 DOI: 10.2337/Db06-0249 |
0.505 |
|
2006 |
Georgia S, Soliz R, Li M, Zhang P, Bhushan A. p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors. Developmental Biology. 298: 22-31. PMID 16899237 DOI: 10.1016/J.Ydbio.2006.05.036 |
0.449 |
|
2006 |
Meier JJ, Bhushan A, Butler PC. The potential for stem cell therapy in diabetes. Pediatric Research. 59: 65R-73R. PMID 16549551 DOI: 10.1203/01.Pdr.0000206857.38581.49 |
0.479 |
|
2006 |
Wang X, Ge S, Gonzalez I, McNamara G, Rountree CB, Xi KK, Huang G, Bhushan A, Crooks GM. Formation of pancreatic duct epithelium from bone marrow during neonatal development. Stem Cells (Dayton, Ohio). 24: 307-14. PMID 16510429 DOI: 10.1634/Stemcells.2005-0052 |
0.331 |
|
2005 |
Meier JJ, Bhushan A, Butler AE, Rizza RA, Butler PC. Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: Indirect evidence for islet regeneration? Diabetologia. 48: 2221-2228. PMID 16205882 DOI: 10.1007/S00125-005-1949-2 |
0.456 |
|
2004 |
Georgia S, Bhushan A. Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. The Journal of Clinical Investigation. 114: 963-8. PMID 15467835 DOI: 10.1172/Jci22098 |
0.476 |
|
2004 |
Wang X, Ge S, McNamara G, Bhushan A. Formation of Pancreatic Duct Cells from Bone Marrow during Neonatal Development. Blood. 104: 675-675. DOI: 10.1182/Blood.V104.11.675.675 |
0.346 |
|
1998 |
Bhushan A, Chen Y, Vale W. Smad7 inhibits mesoderm formation and promotes neural cell fate in Xenopus embryos. Developmental Biology. 200: 260-8. PMID 9705232 DOI: 10.1006/Dbio.1998.8965 |
0.352 |
|
1997 |
Chen Y, Bhushan A, Vale W. Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 12938-43. PMID 9371779 DOI: 10.1073/Pnas.94.24.12938 |
0.306 |
|
1994 |
Bhushan A, Lin HY, Lodish HF, Kintner CR. The transforming growth factor beta type II receptor can replace the activin type II receptor in inducing mesoderm. Molecular and Cellular Biology. 14: 4280-5. PMID 8196664 DOI: 10.1128/Mcb.14.6.4280 |
0.364 |
|
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