Year |
Citation |
Score |
2018 |
Montag J, Petersen B, Flögel AK, Becker E, Lucas-Hahn A, Cost GJ, Mühlfeld C, Kraft T, Niemann H, Brenner B. Successful knock-in of Hypertrophic Cardiomyopathy-mutation R723G into the MYH7 gene mimics HCM pathology in pigs. Scientific Reports. 8: 4786. PMID 29555974 DOI: 10.1038/S41598-018-22936-Z |
0.314 |
|
2018 |
Rajavel S, Ito CE, Abe K, Guerrero V, Uenishi GI, Scharenberg AM, Cost GJ. Chemically Controlled, Immunosuppression-Resistant, Anti-Bcma CAR-T Cells for Treatment of Antibody-Mediated Autoimmunity Blood. 132: 2203-2203. DOI: 10.1182/Blood-2018-99-117630 |
0.333 |
|
2018 |
Uenishi GI, Abe K, Sun B, Mallari C, Scharenberg AM, Cost GJ. Genome Editing Via NHEJ-Mediated Targeted Integration Retains Engraftment Potential of Edited Hematopoietic Stem Cells Blood. 132: 3480-3480. DOI: 10.1182/Blood-2018-99-117488 |
0.432 |
|
2018 |
Montag J, Petersen B, Katharina Flögel A, Becker E, Lucas-Hahn A, Cost GJ, Mühlfeld C, Kraft T, Niemann H, Brenner B. A Genome Edited Pig with the Hypertrophic Cardiomyopathy-Mutation R723G in the MYH7-gene Biophysical Journal. 114: 84a. DOI: 10.1016/J.Bpj.2017.11.502 |
0.346 |
|
2016 |
Hoban MD, Romero Z, Cost GJ, Mendel M, Holmes M, Kohn DB. Delivery of Genome Editing Reagents to Hematopoietic Stem/Progenitor Cells. Current Protocols in Stem Cell Biology. 36: 5B.4.1-5B.4.10. PMID 26840227 DOI: 10.1002/9780470151808.Sc05B04S36 |
0.403 |
|
2016 |
Bjurström CF, Mojadidi M, Lomova A, Lai S, Fitz-Gibbon S, Pellegrini M, Cooper AR, Lill GR, Kaufman M, Cost GJ, Holmes MC, Hollis RP, Kohn DB. Preservation of Gene Edited Hematopoietic Stem Cells By Transient Overexpression of BCL-2 mRNA Blood. 128: 3636-3636. DOI: 10.1182/Blood.V128.22.3636.3636 |
0.407 |
|
2016 |
Conway A, Boyko A, Hardin J, Holmes MC, Cost GJ. 432. Valproic Acid Treatment Enhances Hematopoietic Stem and Progenitor Cell Multipotency Ex Vivo for Enhanced Long-Term Engraftment of Gene-Modified Cells Molecular Therapy. 24: S171. DOI: 10.1016/S1525-0016(16)33241-5 |
0.352 |
|
2016 |
Genovese P, Schiroli G, Conway A, Ferrari S, Guschin DY, Di Tomaso T, Albano L, Marin V, Giuliani E, Gregory PD, Holmes MC, Gentner B, Bovolenta C, Cost GJ, Lombardo A, et al. 37. Towards Clinical Translation of Hematopoietic Stem Cell Gene Editing for the Correction of SCID-X1 Mutations Molecular Therapy. 24: S16-S17. DOI: 10.1016/S1525-0016(16)32846-5 |
0.447 |
|
2015 |
Hoban MD, Cost GJ, Mendel MC, Romero Z, Kaufman ML, Joglekar AV, Ho M, Lumaquin D, Gray D, Lill GR, Cooper AR, Urbinati F, Senadheera S, Zhu A, Liu PQ, et al. Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells. Blood. 125: 2597-604. PMID 25733580 DOI: 10.1182/Blood-2014-12-615948 |
0.427 |
|
2015 |
Conway A, Guschin DY, Genovese P, Lombardo A, Naldini L, Gregory PD, Holmes MC, Cost GJ. 686. Gene Correction of IL2RG in Human Hematopoietic Stem and Progenitor Cells Molecular Therapy. 23: S273. DOI: 10.1016/S1525-0016(16)34295-2 |
0.425 |
|
2015 |
Hoban MD, Mendel MC, Romero Z, Kaufman ML, Joglekar AV, Ho M, Lumaquin D, Gray D, Lill GR, Cooper AR, Urbinati F, Senadheera S, Zhu A, Liu P, Paschon DE, ... ... Cost GJ, et al. 115. Correction of the Sickle-Cell Disease Mutation in Human Hematopoietic Stem/Progenitor Cells Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33720-0 |
0.336 |
|
2015 |
Smith L, Chandra M, Ul-Hasan T, Cost G, Holmes M, Gregory P, Wong K, Chatterjee S. 55. AAVHSC Vectors Encoding Zinc-Finger Nucleases Mediate Efficient Targeted Integration at the Human AAVS1 Locus in CD34+ Human Hematopoietic Stem Cells Molecular Therapy. 23: S24. DOI: 10.1016/S1525-0016(16)33660-7 |
0.478 |
|
2015 |
Hacke K, Treger J, Bogan B, Rezek V, Narukawa M, Shimizu S, Liu P, Reik A, Lieber A, Crooks G, Kohn D, An DS, Kitchen S, Gregory P, Cost G, et al. A novel in vivo chemoselection strategy for genetically modified hematopoietic stem cells Cytotherapy. 17: S52. DOI: 10.1016/J.Jcyt.2015.03.486 |
0.332 |
|
2014 |
Inglese J, Dranchak P, Moran JJ, Jang SW, Srinivasan R, Santiago Y, Zhang L, Guha R, Martinez N, MacArthur R, Cost GJ, Svaren J. Genome editing-enabled HTS assays expand drug target pathways for Charcot-Marie-tooth disease. Acs Chemical Biology. 9: 2594-602. PMID 25188731 DOI: 10.1021/Cb5005492 |
0.358 |
|
2014 |
Sexton AN, Regalado SG, Lai CS, Cost GJ, O'Neil CM, Urnov FD, Gregory PD, Jaenisch R, Collins K, Hockemeyer D. Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation. Genes & Development. 28: 1885-99. PMID 25128433 DOI: 10.1101/Gad.246819.114 |
0.371 |
|
2014 |
Remy S, Tesson L, Menoret S, Usal C, De Cian A, Thepenier V, Thinard R, Baron D, Charpentier M, Renaud JB, Buelow R, Cost GJ, Giovannangeli C, Fraichard A, Concordet JP, et al. Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases. Genome Research. 24: 1371-83. PMID 24989021 DOI: 10.1101/Gr.171538.113 |
0.407 |
|
2014 |
Forster R, Chiba K, Schaeffer L, Regalado SG, Lai CS, Gao Q, Kiani S, Farin HF, Clevers H, Cost GJ, Chan A, Rebar EJ, Urnov FD, Gregory PD, Pachter L, et al. Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells. Stem Cell Reports. 2: 838-52. PMID 24936470 DOI: 10.1016/J.Stemcr.2014.05.001 |
0.325 |
|
2014 |
Conway A, Laganière J, Paschon DE, Hacke K, Kasahara N, Gregory PD, Holmes MC, Cost GJ. HPRT As a Selectable Safe Harbor for Transgenesis Blood. 124: 4796-4796. DOI: 10.1182/Blood.V124.21.4796.4796 |
0.429 |
|
2013 |
Jiang J, Jing Y, Cost GJ, Chiang JC, Kolpa HJ, Cotton AM, Carone DM, Carone BR, Shivak DA, Guschin DY, Pearl JR, Rebar EJ, Byron M, Gregory PD, Brown CJ, et al. Translating dosage compensation to trisomy 21. Nature. 500: 296-300. PMID 23863942 DOI: 10.1038/Nature12394 |
0.353 |
|
2013 |
Hauschild-Quintern J, Petersen B, Cost GJ, Niemann H. Gene knockout and knockin by zinc-finger nucleases: Current status and perspectives Cellular and Molecular Life Sciences. 70: 2969-2983. PMID 23161061 DOI: 10.1007/S00018-012-1204-1 |
0.449 |
|
2013 |
Cristea S, Freyvert Y, Santiago Y, Holmes MC, Urnov FD, Gregory PD, Cost GJ. In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration. Biotechnology and Bioengineering. 110: 871-80. PMID 23042119 DOI: 10.1002/Bit.24733 |
0.434 |
|
2013 |
Hoban MD, Joglekar AV, Gray D, Kaufman ML, Urbinati F, Senadheera S, Cost G, Reik A, Holmes MC, Gregory PD, Hollis RP, Kohn DB. Zinc Finger Nucleases Targeting The β-Globin Locus Drive Efficient Correction Of The Sickle Mutation In CD34+ Cells Blood. 122: 2904-2904. DOI: 10.1182/Blood.V122.21.2904.2904 |
0.425 |
|
2012 |
Hauschild J, Petersen B, Santiago Y, Queisser AL, Carnwath JW, Lucas-Hahn A, Zhang L, Meng X, Gregory PD, Schwinzer R, Cost GJ, Niemann H. 233 GENDER-UNSPECIFIC KNOCKOUT OF THE GGTA1 GENE IN PIGS USING ZINC FINGER NUCLEASES Reproduction, Fertility and Development. 24: 229. DOI: 10.1071/Rdv24N1Ab233 |
0.411 |
|
2011 |
Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng X, Hinkley SJ, Rebar EJ, et al. Genetic engineering of human pluripotent cells using TALE nucleases. Nature Biotechnology. 29: 731-4. PMID 21738127 DOI: 10.1038/Nbt.1927 |
0.413 |
|
2011 |
Hauschild J, Petersen B, Santiago Y, Queisser AL, Carnwath JW, Lucas-Hahn A, Zhang L, Meng X, Gregory PD, Schwinzer R, Cost GJ, Niemann H. Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases. Proceedings of the National Academy of Sciences of the United States of America. 108: 12013-7. PMID 21730124 DOI: 10.1073/Pnas.1106422108 |
0.427 |
|
2011 |
Cristea S, Gregory PD, Urnov FD, Cost GJ. Dissection of splicing regulation at an endogenous locus by zinc-finger nuclease-mediated gene editing. Plos One. 6: e16961. PMID 21347446 DOI: 10.1371/Journal.Pone.0016961 |
0.386 |
|
2011 |
Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, et al. A TALE nuclease architecture for efficient genome editing. Nature Biotechnology. 29: 143-8. PMID 21179091 DOI: 10.1038/Nbt.1755 |
0.445 |
|
2011 |
Hauschild J, Queisser AL, Carnwath JW, Cost G, Santiago Y, Rebar E, Gregory P, Niemann H, Petersen B. 329 GENETIC TARGETING OF THE PORCINE α1,3-GALACTOSYLTRANSFERASE GENE IN FETAL FIBROBLAST CELLS USING ZINC FINGER NUCLEASES Reproduction, Fertility and Development. 23: 260. DOI: 10.1071/Rdv23N1Ab329 |
0.438 |
|
2010 |
Ménoret S, Iscache AL, Tesson L, Rémy S, Usal C, Osborn MJ, Cost GJ, Brüggemann M, Buelow R, Anegon I. Characterization of immunoglobulin heavy chain knockout rats. European Journal of Immunology. 40: 2932-41. PMID 21038471 DOI: 10.1002/Eji.201040939 |
0.313 |
|
2010 |
Malphettes L, Freyvert Y, Chang J, Liu PQ, Chan E, Miller JC, Zhou Z, Nguyen T, Tsai C, Snowden AW, Collingwood TN, Gregory PD, Cost GJ. Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies. Biotechnology and Bioengineering. 106: 774-83. PMID 20564614 DOI: 10.1002/Bit.22751 |
0.326 |
|
2010 |
Orlando SJ, Santiago Y, DeKelver RC, Freyvert Y, Boydston EA, Moehle EA, Choi VM, Gopalan SM, Lou JF, Li J, Miller JC, Holmes MC, Gregory PD, Urnov FD, Cost GJ. Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology. Nucleic Acids Research. 38: e152. PMID 20530528 DOI: 10.1093/Nar/Gkq512 |
0.431 |
|
2010 |
Liu PQ, Chan EM, Cost GJ, Zhang L, Wang J, Miller JC, Guschin DY, Reik A, Holmes MC, Mott JE, Collingwood TN, Gregory PD. Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases. Biotechnology and Bioengineering. 106: 97-105. PMID 20047187 DOI: 10.1002/Bit.22654 |
0.452 |
|
2010 |
Geurts AM, Cost GJ, Rémy S, Cui X, Tesson L, Usal C, Ménoret S, Jacob HJ, Anegon I, Buelow R. Generation of gene-specific mutated rats using zinc-finger nucleases. Methods in Molecular Biology (Clifton, N.J.). 597: 211-25. PMID 20013236 DOI: 10.1007/978-1-60327-389-3_15 |
0.396 |
|
2010 |
Cost GJ, Freyvert Y, Vafiadis A, Santiago Y, Miller JC, Rebar E, Collingwood TN, Snowden A, Gregory PD. BAK and BAX deletion using zinc-finger nucleases yields apoptosis-resistant CHO cells. Biotechnology and Bioengineering. 105: 330-40. PMID 19777580 DOI: 10.1002/Bit.22541 |
0.319 |
|
2009 |
Scheifele LZ, Cost GJ, Zupancic ML, Caputo EM, Boeke JD. Retrotransposon overdose and genome integrity. Proceedings of the National Academy of Sciences of the United States of America. 106: 13927-32. PMID 19666515 DOI: 10.1073/Pnas.0906552106 |
0.538 |
|
2009 |
Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, et al. Knockout rats via embryo microinjection of zinc-finger nucleases. Science (New York, N.Y.). 325: 433. PMID 19628861 DOI: 10.1126/Science.1172447 |
0.41 |
|
2007 |
Cost GJ. Enzymatic ligation assisted by nucleases: simultaneous ligation and digestion promote the ordered assembly of DNA. Nature Protocols. 2: 2198-202. PMID 17853876 DOI: 10.1038/Nprot.2007.325 |
0.341 |
|
2007 |
Cost GJ, Cozzarelli NR. Directed assembly of DNA molecules via simultaneous ligation and digestion. Biotechniques. 42: 84, 86-9. PMID 17269489 DOI: 10.2144/000112283 |
0.341 |
|
2006 |
Cozzarelli NR, Cost GJ, Nöllmann M, Viard T, Stray JE. Giant proteins that move DNA: bullies of the genomic playground. Nature Reviews. Molecular Cell Biology. 7: 580-8. PMID 16936698 DOI: 10.1038/Nrm1982 |
0.379 |
|
2006 |
Cost GJ, Cozzarelli NR. Smc5p promotes faithful chromosome transmission and DNA repair in Saccharomyces cerevisiae. Genetics. 172: 2185-200. PMID 16452135 DOI: 10.1534/Genetics.105.053876 |
0.355 |
|
2005 |
Pease PJ, Levy O, Cost GJ, Gore J, Ptacin JL, Sherratt D, Bustamante C, Cozzarelli NR. Sequence-directed DNA translocation by purified FtsK. Science (New York, N.Y.). 307: 586-90. PMID 15681387 DOI: 10.1126/Science.1104885 |
0.353 |
|
2002 |
Cost GJ, Feng Q, Jacquier A, Boeke JD. Human L1 element target-primed reverse transcription in vitro. The Embo Journal. 21: 5899-910. PMID 12411507 DOI: 10.1093/Emboj/Cdf592 |
0.511 |
|
2002 |
Symer DE, Connelly C, Szak ST, Caputo EM, Cost GJ, Parmigiani G, Boeke JD. Human l1 retrotransposition is associated with genetic instability in vivo. Cell. 110: 327-38. PMID 12176320 DOI: 10.1016/S0092-8674(02)00839-5 |
0.529 |
|
2001 |
Cost GJ, Golding A, Schlissel MS, Boeke JD. Target DNA chromatinization modulates nicking by L1 endonuclease. Nucleic Acids Research. 29: 573-7. PMID 11139628 DOI: 10.1093/Nar/29.2.573 |
0.548 |
|
1998 |
Cost GJ, Boeke JD. Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure. Biochemistry. 37: 18081-93. PMID 9922177 DOI: 10.1021/Bi981858S |
0.543 |
|
1998 |
Brachmann CB, Davies A, Cost GJ, Caputo E, Li J, Hieter P, Boeke JD. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast (Chichester, England). 14: 115-32. PMID 9483801 DOI: 10.1002/(Sici)1097-0061(19980130)14:2<115::Aid-Yea204>3.0.Co;2-2 |
0.513 |
|
1996 |
Cost GJ, Boeke JD. A useful colony colour phenotype associated with the yeast selectable/counter-selectable marker MET15. Yeast (Chichester, England). 12: 939-41. PMID 8873447 DOI: 10.1002/(Sici)1097-0061(199608)12:10<939::Aid-Yea988>3.0.Co;2-L |
0.479 |
|
1995 |
Ess KC, Whitaker TL, Cost GJ, Witte DP, Hutton JJ, Aronow BJ. A central role for a single c-Myb binding site in a thymic locus control region. Molecular and Cellular Biology. 15: 5707-15. PMID 7565722 DOI: 10.1128/Mcb.15.10.5707 |
0.349 |
|
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