Dasiel Oscar Borroto-Escuela - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 
Area:
GPCR

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Borroto-Escuela DO, Fuxe K. On the G Protein-Coupled Receptor Neuromodulation of the Claustrum. Neurochemical Research. PMID 31172348 DOI: 10.1007/s11064-019-02822-4  1
2019 Fuxe K, Borroto-Escuela DO. Understanding receptor heteromerization and its allosteric integration of signals. Neuropharmacology. PMID 31054939 DOI: 10.1016/j.neuropharm.2019.05.001  1
2019 Chruścicka B, Wallace Fitzsimons SE, Borroto-Escuela DO, Druelle C, Stamou P, Nally K, Dinan TG, Cryan JF, Fuxe K, Schellekens H. Attenuation of Oxytocin and Serotonin 2A Receptor Signalling through Novel Heteroreceptor Formation. Acs Chemical Neuroscience. PMID 31038917 DOI: 10.1021/acschemneuro.8b00665  1
2019 Borroto-Escuela DO, Narváez M, Romero-Fernández W, Pinton L, Wydra K, Filip M, Beggiato S, Tanganelli S, Ferraro L, Fuxe K. Acute Cocaine Enhances Dopamine DR Recognition and Signaling and Counteracts DR Internalization in Sigma1R-DR Heteroreceptor Complexes. Molecular Neurobiology. PMID 30972626 DOI: 10.1007/s12035-019-1580-8  1
2019 Borroto-Escuela DO, Fuxe K. Adenosine heteroreceptor complexes in the basal ganglia are implicated in Parkinson's disease and its treatment. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 30637481 DOI: 10.1007/s00702-019-01969-2  1
2018 Borroto-Escuela DO, Wydra K, Filip M, Fuxe K. A2AR-D2R Heteroreceptor Complexes in Cocaine Reward and Addiction. Trends in Pharmacological Sciences. 39: 1008-1020. PMID 30384981 DOI: 10.1016/j.tips.2018.10.007  1
2018 Borroto-Escuela DO, Rodriguez D, Romero-Fernandez W, Kapla J, Jaiteh M, Ranganathan A, Lazarova T, Fuxe K, Carlsson J. Mapping the Interface of a GPCR Dimer: A Structural Model of the A Adenosine and D Dopamine Receptor Heteromer. Frontiers in Pharmacology. 9: 829. PMID 30214407 DOI: 10.3389/fphar.2018.00829  1
2018 Borroto-Escuela DO, Tarakanov AO, Brito I, Fuxe K. Glutamate heteroreceptor complexes in the brain. Pharmacological Reports : Pr. 70: 936-950. PMID 30103174 DOI: 10.1016/j.pharep.2018.04.002  1
2018 Borroto-Escuela DO, Perez De La Mora M, Manger P, Narváez M, Beggiato S, Crespo-Ramírez M, Navarro G, Wydra K, Díaz-Cabiale Z, Rivera A, Ferraro L, Tanganelli S, Filip M, Franco R, Fuxe K. Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors. Frontiers in Synaptic Neuroscience. 10: 20. PMID 30042672 DOI: 10.3389/fnsyn.2018.00020  1
2018 Kostrzewa RM, Wydra K, Filip M, Crawford C, McDougall SA, Brown RW, Borroto-Escuela DO, Fuxe K, Gainetdinov RR. Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders. The Journal of Pharmacology and Experimental Therapeutics. PMID 29921706 DOI: 10.1124/jpet.118.247981  1
2018 Borroto-Escuela DO, Narváez M, Ambrogini P, Ferraro L, Brito I, Romero-Fernandez W, Andrade-Talavera Y, Flores-Burgess A, Millon C, Gago B, Narvaez JA, Odagaki Y, Palkovits M, Diaz-Cabiale Z, Fuxe K. Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment. Molecules (Basel, Switzerland). 23. PMID 29865267 DOI: 10.3390/molecules23061341  1
2018 Narváez M, Borroto-Escuela DO, Santín L, Millón C, Gago B, Flores-Burgess A, Barbancho MA, Pérez de la Mora M, Narváez J, Díaz-Cabiale Z, Fuxe K. A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats. Frontiers in Cellular Neuroscience. 12: 119. PMID 29765307 DOI: 10.3389/fncel.2018.00119  1
2018 Borroto-Escuela DO, Hinz S, Navarro G, Franco R, Müller CE, Fuxe K. Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation. Frontiers in Neuroscience. 12: 43. PMID 29467608 DOI: 10.3389/fnins.2018.00043  1
2018 Borroto-Escuela DO, Wydra K, Li X, Rodriguez D, Carlsson J, Jastrzębska J, Filip M, Fuxe K. Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats. Molecular Neurobiology. PMID 29383683 DOI: 10.1007/s12035-018-0887-1  1
2018 Hernández-Pérez OR, Crespo-Ramírez M, Cuza-Ferrer Y, Anias-Calderón J, Zhang L, Roldan-Roldan G, Aguilar-Roblero R, Borroto-Escuela DO, Fuxe K, Perez de la Mora M. Differential activation of arginine-vasopressin receptor subtypes in the amygdaloid modulation of anxiety in the rat by arginine-vasopressin. Psychopharmacology. PMID 29306965 DOI: 10.1007/s00213-017-4817-0  1
2017 Borroto-Escuela DO, DuPont CM, Li X, Savelli D, Lattanzi D, Srivastava I, Narváez M, Di Palma M, Barbieri E, Andrade-Talavera Y, Cuppini R, Odagaki Y, Palkovits M, Ambrogini P, Lindskog M, et al. Disturbances in the FGFR1-5-HT1A Heteroreceptor Complexes in the Raphe-Hippocampal 5-HT System Develop in a Genetic Rat Model of Depression. Frontiers in Cellular Neuroscience. 11: 309. PMID 29066953 DOI: 10.3389/fncel.2017.00309  1
2017 Borroto-Escuela DO, Li X, Tarakanov AO, Savelli D, Narváez M, Shumilov K, Andrade-Talavera Y, Jimenez-Beristain A, Pomierny B, Díaz-Cabiale Z, Cuppini R, Ambrogini P, Lindskog M, Fuxe K. Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition. Acs Omega. 2: 4779-4789. PMID 28920103 DOI: 10.1021/acsomega.7b00629  1
2017 Borroto-Escuela DO, Narváez M, Wydra K, Pintsuk J, Pinton L, Jimenez-Beristain A, Di Palma M, Jastrzębska J, Filip M, Fuxe K. Cocaine self-administration specifically increases A2AR-D2R and D2R-sigma1R heteroreceptor complexes in the rat nucleus accumbens shell. Relevance for cocaine use disorder. Pharmacology, Biochemistry, and Behavior. 155: 24-31. PMID 28300546 DOI: 10.1016/j.pbb.2017.03.003  1
2017 Flores-Burgess A, Millón C, Gago B, Narváez M, Borroto-Escuela DO, Mengod G, Narváez JA, Fuxe K, Santín L, Díaz-Cabiale Z. Galanin (1-15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression. Neuropharmacology. PMID 28288814 DOI: 10.1016/j.neuropharm.2017.03.010  1
2017 Borroto-Escuela DO, Carlsson J, Ambrogini P, Narváez M, Wydra K, Tarakanov AO, Li X, Millón C, Ferraro L, Cuppini R, Tanganelli S, Liu F, Filip M, Diaz-Cabiale Z, Fuxe K. Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease. Frontiers in Cellular Neuroscience. 11: 37. PMID 28270751 DOI: 10.3389/fncel.2017.00037  1
2017 Borroto-Escuela DO, Tarakanov AO, Bechter K, Fuxe K. IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia. Frontiers in Psychiatry. 8: 24. PMID 28261115 DOI: 10.3389/fpsyt.2017.00024  1
2017 Millón C, Flores-Burgess A, Narváez M, Borroto-Escuela DO, Gago B, Santín L, Castilla-Ortega E, Narváez JÁ, Fuxe K, Díaz-Cabiale Z. The neuropeptides Galanin and Galanin(1-15) in depression-like behaviours. Neuropeptides. PMID 28196617 DOI: 10.1016/j.npep.2017.01.004  1
2016 Pintsuk J, Borroto-Escuela DO, Lai TK, Liu F, Fuxe K. Alterations in ventral and dorsal striatal allosteric A2AR-D2R receptor-receptor interactions after amphetamine challenge: Relevance for schizophrenia. Life Sciences. PMID 27984074 DOI: 10.1016/j.lfs.2016.10.027  1
2016 Borroto-Escuela DO, Wydra K, Pintsuk J, Narvaez M, Corrales F, Zaniewska M, Agnati LF, Franco R, Tanganelli S, Ferraro L, Filip M, Fuxe K. Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes. Neural Plasticity. 2016: 4827268. PMID 27872762 DOI: 10.1155/2016/4827268  1
2016 Borroto-Escuela DO, Fuxe K. Diversity and bias through dopamine D2R heteroreceptor complexes. Current Opinion in Pharmacology. 32: 16-22. PMID 27838588 DOI: 10.1016/j.coph.2016.10.004  1
2016 Fuxe K, Borroto-Escuela DO. Volume transmission and receptor-receptor interactions in heteroreceptor complexes: understanding the role of new concepts for brain communication. Neural Regeneration Research. 11: 1220-3. PMID 27651759 DOI: 10.4103/1673-5374.189168  1
2016 de la Mora MP, Pérez-Carrera D, Crespo-Ramírez M, Tarakanov A, Fuxe K, Borroto-Escuela DO. Signaling in dopamine D2 receptor-Oxytocin receptor heterocomplexes and its relevance for the anxiolytic effects of dopamine and oxytocin interactions in the amygdala of the rat. Biochimica Et Biophysica Acta. PMID 27425032 DOI: 10.1016/j.bbadis.2016.07.004  1
2016 Rivera A, Gago B, Suárez-Boomgaard D, Yoshitake T, Roales-Buján R, Valderrama-Carvajal A, Bilbao A, Medina-Luque J, Díaz-Cabiale Z, Craenenbroeck KV, Borroto-Escuela DO, Kehr J, Rodríguez de Fonseca F, Santín L, de la Calle A, et al. Dopamine D4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction. Addiction Biology. PMID 27212105 DOI: 10.1111/adb.12407  1
2016 Skieterska K, Shen A, Clarisse D, Rondou P, Borroto-Escuela DO, Lintermans B, Fuxe K, Xiang YK, Van Craenenbroeck K. Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins. Cellular Signalling. PMID 27155323 DOI: 10.1016/j.cellsig.2016.05.003  1
2016 Borroto-Escuela DO, Pintsuk J, Schäfer T, Friedland K, Ferraro L, Tanganelli S, Liu F, Fuxe K. Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia. Therapeutic Advances in Psychopharmacology. 6: 77-94. PMID 27141290 DOI: 10.1177/2045125316637570  1
2016 Beggiato S, Tomasini MC, Borelli AC, Borroto-Escuela DO, Fuxe K, Antonelli T, Tanganelli S, Ferraro L. Functional role of striatal A2A, D2 and mGlu5 receptor interactions in regulating striatopallidal GABA neuron transmission. Journal of Neurochemistry. PMID 27127992 DOI: 10.1111/jnc.13652  1
2016 Pintsuk J, Borroto-Escuela DO, Pomierny B, Wydra K, Zaniewska M, Filip M, Fuxe K. Cocaine self-administration differentially affects allosteric A2A-D2 receptor-receptor interactions in the striatum. Relevance for cocaine use disorder. Pharmacology, Biochemistry, and Behavior. PMID 26987369 DOI: 10.1016/j.pbb.2016.03.004  1
2016 Millón C, Flores-Burgess A, Narváez M, Borroto-Escuela DO, Santín L, Gago B, Narváez JA, Fuxe K, Díaz-Cabiale Z. Galanin (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT: involvement of the raphe-hippocampal 5-HT neuron system. Brain Structure & Function. PMID 26792005 DOI: 10.1007/s00429-015-1180-y  1
2016 Fuxe K, Borroto-Escuela DO. Heteroreceptor Complexes and their Allosteric Receptor-Receptor Interactions as a Novel Biological Principle for Integration of Communication in the CNS: Targets for Drug Development. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 41: 380-2. PMID 26657959 DOI: 10.1038/npp.2015.244  1
2016 Borroto-Escuela DO, Hagman B, Woolfenden M, Pinton L, Jiménez-Beristain A, Oflijan J, Narvaez M, Di Palma M, Feltmann K, Sartini S, Ambrogini P, Ciruela F, Cuppini R, Fuxe K. In situ proximity ligation assay to study and understand the distribution and balance of GPCR homo- and heteroreceptor complexes in the brain Neuromethods. 110: 109-124. DOI: 10.1007/978-1-4939-3064-7_9  1
2016 Morató X, Borroto-Escuela DO, Fuxe K, Fernández-Dueñas V, Ciruela F. Co-immunoprecipitation from brain Neuromethods. 110: 19-29. DOI: 10.1007/978-1-4939-3064-7_2  1
2015 Borroto-Escuela DO, Tarakanov AO, Fuxe K. FGFR1-5-HT1A Heteroreceptor Complexes: Implications for Understanding and Treating Major Depression. Trends in Neurosciences. PMID 26687454 DOI: 10.1016/j.tins.2015.11.003  1
2015 Narváez M, Borroto-Escuela DO, Millón C, Gago B, Flores-Burgess A, Santín L, Fuxe K, Narváez JA, Díaz-Cabiale Z. Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the dentate gyrus are related with antidepressant-like effects. Brain Structure & Function. PMID 26666529 DOI: 10.1007/s00429-015-1153-1  1
2015 Agnati LF, Guidolin D, Cervetto C, Borroto-Escuela DO, Fuxe K. Role of iso-receptors in receptor-receptor interactions with a focus on dopamine iso-receptor complexes. Reviews in the Neurosciences. PMID 26418645 DOI: 10.1515/revneuro-2015-0024  1
2015 Tena-Campos M, Ramon E, Borroto-Escuela DO, Fuxe K, Garriga P. The zinc binding receptor GPR39 interacts with 5-HT1A and GalR1 to form dynamic heteroreceptor complexes with signaling diversity. Biochimica Et Biophysica Acta. 1852: 2585-2592. PMID 26365466 DOI: 10.1016/j.bbadis.2015.09.003  1
2015 Fuxe K, Borroto-Escuela DO. Basimglurant for treatment of major depressive disorder: a novel negative allosteric modulator of metabotropic glutamate receptor 5. Expert Opinion On Investigational Drugs. 24: 1247-60. PMID 26219727 DOI: 10.1517/13543784.2015.1074175  1
2015 Navarro G, Borroto-Escuela DO, Fuxe K, Franco R. Purinergic signaling in Parkinson's disease. Relevance for treatment. Neuropharmacology. PMID 26211977 DOI: 10.1016/j.neuropharm.2015.07.024  1
2015 Borroto-Escuela DO, Agnati LF, Bechter K, Jansson A, Tarakanov AO, Fuxe K. The role of transmitter diffusion and flow versus extracellular vesicles in volume transmission in the brain neural-glial networks. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26009762 DOI: 10.1098/rstb.2014.0183  1
2015 Borroto-Escuela DO, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Jiménez-Beristain A, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Enhancement of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems. Relevance for neuroplasticity and depression. Biochemical and Biophysical Research Communications. 463: 180-6. PMID 25957476 DOI: 10.1016/j.bbrc.2015.04.133  1
2015 Fuxe K, Agnati LF, Marcoli M, Borroto-Escuela DO. Volume Transmission in Central Dopamine and Noradrenaline Neurons and Its Astroglial Targets. Neurochemical Research. PMID 25894681 DOI: 10.1007/s11064-015-1574-5  1
2015 Millón C, Flores-Burgess A, Narváez M, Borroto-Escuela DO, Santín L, Parrado C, Narváez JA, Fuxe K, Díaz-Cabiale Z. A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522404 DOI: 10.1093/ijnp/pyu064  1
2015 Fuxe K, Guidolin D, Agnati LF, Borroto-Escuela DO. Dopamine heteroreceptor complexes as therapeutic targets in Parkinson's disease. Expert Opinion On Therapeutic Targets. 19: 377-98. PMID 25486101 DOI: 10.1517/14728222.2014.981529  1
2015 Borroto-Escuela DO, Narvaez M, Pérez-Alea M, Tarakanov AO, Jiménez-Beristain A, Mudó G, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Evidence for the existence of FGFR1-5-HT1A heteroreceptor complexes in the midbrain raphe 5-HT system. Biochemical and Biophysical Research Communications. 456: 489-93. PMID 25485703 DOI: 10.1016/j.bbrc.2014.11.112  1
2015 Wydra K, Suder A, Borroto-Escuela DO, Filip M, Fuxe K. On the role of A₂A and D₂ receptors in control of cocaine and food-seeking behaviors in rats. Psychopharmacology. 232: 1767-78. PMID 25420611 DOI: 10.1007/s00213-014-3818-5  1
2015 Guidolin D, Agnati LF, Marcoli M, Borroto-Escuela DO, Fuxe K. G-protein-coupled receptor type A heteromers as an emerging therapeutic target. Expert Opinion On Therapeutic Targets. 19: 265-83. PMID 25381716 DOI: 10.1517/14728222.2014.981155  1
2015 Narváez M, Millón C, Borroto-Escuela D, Flores-Burgess A, Santín L, Parrado C, Gago B, Puigcerver A, Fuxe K, Narváez JA, Díaz-Cabiale Z. Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the amygdala lead to increased anxiolytic actions. Brain Structure & Function. 220: 2289-301. PMID 24841617 DOI: 10.1007/s00429-014-0788-7  1
2014 Navarro G, Borroto-Escuela DO, Fuxe K, Franco R. Potential of caveolae in the therapy of cardiovascular and neurological diseases. Frontiers in Physiology. 5: 370. PMID 25324780 DOI: 10.3389/fphys.2014.00370  1
2014 Romero-Fernandez W, Borroto-Escuela DO, Vargas-Barroso V, Narváez M, Di Palma M, Agnati LF, Larriva Sahd J, Fuxe K. Dopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complex and their link to the tubero-infundibular dopamine neurons. European Journal of Histochemistry : Ejh. 58: 2400. PMID 25308843 DOI: 10.4081/ejh.2014.2400  1
2014 Fuxe K, Borroto-Escuela D, Fisone G, Agnati LF, Tanganelli S. Understanding the role of heteroreceptor complexes in the central nervous system. Current Protein & Peptide Science. 15: 647. PMID 25256022  1
2014 Tena-Campos M, Ramon E, Rivera D, Borroto-Escuela DO, Romero-Fernandez W, Fuxe K, Garriga P. G-protein-coupled receptors oligomerization: emerging signaling units and new opportunities for drug design. Current Protein & Peptide Science. 15: 648-58. PMID 25175459  1
2014 Ferraro L, Beggiato S, Borroto-Escuela DO, Ravani L, O'Connor WT, Tomasini MC, Borelli AC, Agnati LF, Antonelli T, Tanganelli S, Fuxe K. Neurotensin NTS1-dopamine D2 receptor-receptor interactions in putative receptor heteromers: relevance for Parkinson's disease and schizophrenia. Current Protein & Peptide Science. 15: 681-90. PMID 25175457  1
2014 Van Craenenbroeck K, Borroto-Escuela DO, Skieterska K, Duchou J, Romero-Fernandez W, Fuxe K. Role of dimerization in dopamine D(4) receptor biogenesis. Current Protein & Peptide Science. 15: 659-65. PMID 25175456  1
2014 Agnati LF, Guidolin D, Marcoli M, Genedani S, Borroto-Escuela D, Maura G, Fuxe K. "Neuro-semeiotics" and "free-energy minimization" suggest a unified perspective for integrative brain actions: focus on receptor heteromers and Roamer type of volume transmission. Current Protein & Peptide Science. 15: 703-18. PMID 25175453  1
2014 Borroto-Escuela DO, Narvaez M, Di Palma M, Calvo F, Rodriguez D, Millon C, Carlsson J, Agnati LF, Garriga P, Díaz-Cabiale Z, Fuxe K. Preferential activation by galanin 1-15 fragment of the GalR1 protomer of a GalR1-GalR2 heteroreceptor complex. Biochemical and Biophysical Research Communications. 452: 347-53. PMID 25152404 DOI: 10.1016/j.bbrc.2014.08.061  1
2014 Fuxe K, Borroto-Escuela DO, Tarakanov AO, Romero-Fernandez W, Ferraro L, Tanganelli S, Perez-Alea M, Di Palma M, Agnati LF. Dopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: novel targets for antipsychotic drugs. Progress in Brain Research. 211: 113-39. PMID 24968778 DOI: 10.1016/B978-0-444-63425-2.00005-2  1
2014 Fuxe K, Agnati LF, Borroto-Escuela DO. The impact of receptor-receptor interactions in heteroreceptor complexes on brain plasticity. Expert Review of Neurotherapeutics. 14: 719-21. PMID 24894440 DOI: 10.1586/14737175.2014.922878  1
2014 Agnati LF, Guidolin D, Maura G, Marcoli M, Leo G, Carone C, De Caro R, Genedani S, Borroto-Escuela DO, Fuxe K. Information handling by the brain: proposal of a new "paradigm" involving the roamer type of volume transmission and the tunneling nanotube type of wiring transmission. Journal of Neural Transmission (Vienna, Austria : 1996). 121: 1431-49. PMID 24866694 DOI: 10.1007/s00702-014-1240-0  1
2014 Fuxe K, Tarakanov A, Romero Fernandez W, Ferraro L, Tanganelli S, Filip M, Agnati LF, Garriga P, Diaz-Cabiale Z, Borroto-Escuela DO. Diversity and Bias through Receptor-Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization. Frontiers in Endocrinology. 5: 71. PMID 24860548 DOI: 10.3389/fendo.2014.00071  1
2014 Borroto-Escuela DO, Brito I, Romero-Fernandez W, Di Palma M, Oflijan J, Skieterska K, Duchou J, Van Craenenbroeck K, Suárez-Boomgaard D, Rivera A, Guidolin D, Agnati LF, Fuxe K. The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components. International Journal of Molecular Sciences. 15: 8570-90. PMID 24830558 DOI: 10.3390/ijms15058570  1
2014 Suárez-Boomgaard D, Gago B, Valderrama-Carvajal A, Roales-Buján R, Craenenbroeck KV, Duchou J, Borroto-Escuela DO, Medina-Luque J, de la Calle A, Fuxe K, Rivera A. Dopamine Dâ‚„ receptor counteracts morphine-induced changes in µ opioid receptor signaling in the striosomes of the rat caudate putamen. International Journal of Molecular Sciences. 15: 1481-98. PMID 24451133 DOI: 10.3390/ijms15011481  1
2014 Borroto-Escuela DO, Romero-Fernandez W, Narvaez M, Oflijan J, Agnati LF, Fuxe K. Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes. Biochemical and Biophysical Research Communications. 443: 278-84. PMID 24309097 DOI: 10.1016/j.bbrc.2013.11.104  1
2014 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Palkovits M, Tarakanov AO, Ciruela F, Agnati LF. Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 131-55. PMID 24105074 DOI: 10.1038/npp.2013.242  1
2014 Ferraro L, Beggiato S, Borroto-Escuela DO, Ravani L, O'connor WT, Tomasini MC, Borelli AC, Agnati LF, Antonelli T, Tanganelli S, Fuxe K. Neurotensin nts1-dopamine d2 receptor-receptor interactions in putative receptor heteromers: Relevance for parkinson’s disease and schizophrenia Current Protein and Peptide Science. 15: 703-718.  1
2013 Borroto-Escuela DO, Corrales F, Narvaez M, Oflijan J, Agnati LF, Palkovits M, Fuxe K. Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2. Biochemical and Biophysical Research Communications. 441: 387-92. PMID 24157794 DOI: 10.1016/j.bbrc.2013.10.067  1
2013 Borroto-Escuela DO, Flajolet M, Agnati LF, Greengard P, Fuxe K. Bioluminescence resonance energy transfer methods to study G protein-coupled receptor-receptor tyrosine kinase heteroreceptor complexes. Methods in Cell Biology. 117: 141-64. PMID 24143976 DOI: 10.1016/B978-0-12-408143-7.00008-6  1
2013 Borroto-Escuela DO, Romero-Fernandez W, Rivera A, Van Craenenbroeck K, Tarakanov AO, Agnati LF, Fuxe K. On the g-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation. Evidence-Based Complementary and Alternative Medicine : Ecam. 2013: 563716. PMID 23956775 DOI: 10.1155/2013/563716  1
2013 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Zhang WB, Agnati LF. Volume transmission and its different forms in the central nervous system. Chinese Journal of Integrative Medicine. 19: 323-9. PMID 23674109 DOI: 10.1007/s11655-013-1455-1  1
2013 Borroto-Escuela DO, Ravani A, Tarakanov AO, Brito I, Narvaez M, Romero-Fernandez W, Corrales F, Agnati LF, Tanganelli S, Ferraro L, Fuxe K. Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers. Biochemical and Biophysical Research Communications. 435: 140-6. PMID 23624386 DOI: 10.1016/j.bbrc.2013.04.058  1
2013 Borroto-Escuela DO, Romero-Fernandez W, Garriga P, Ciruela F, Narvaez M, Tarakanov AO, Palkovits M, Agnati LF, Fuxe K. G protein-coupled receptor heterodimerization in the brain. Methods in Enzymology. 521: 281-94. PMID 23351745 DOI: 10.1016/B978-0-12-391862-8.00015-6  1
2013 Romero-Fernandez W, Borroto-Escuela DO, Agnati LF, Fuxe K. Evidence for the existence of dopamine D2-oxytocin receptor heteromers in the ventral and dorsal striatum with facilitatory receptor-receptor interactions. Molecular Psychiatry. 18: 849-50. PMID 22824810 DOI: 10.1038/mp.2012.103  1
2013 Fuxe K, Borroto-Escuela DO, Tarakanov A, Fernandez WR, Manger P, Rivera A, Van Craenenbroeck K, Skieterska K, Diaz-Cabiale Z, Filip M, Ferraro L, Tanganelli S, Guidolin D, Cullheim S, De La Mora MP, et al. Understanding the balance and integration of volume and synaptic transmission. Relevance for psychiatry Neurology Psychiatry and Brain Research. 19: 141-158. DOI: 10.1016/j.npbr.2013.10.002  1
2012 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Calvo F, Garriga P, Tena M, Narvaez M, Millón C, Parrado C, Ciruela F, Agnati LF, Narvaez JA, Díaz-Cabiale Z. On the existence and function of galanin receptor heteromers in the central nervous system. Frontiers in Endocrinology. 3: 127. PMID 23112793 DOI: 10.3389/fendo.2012.00127  1
2012 Fernández-Dueñas V, Gómez-Soler M, Jacobson KA, Kumar ST, Fuxe K, Borroto-Escuela DO, Ciruela F. Molecular determinants of A2AR-D2R allosterism: role of the intracellular loop 3 of the D2R. Journal of Neurochemistry. 123: 373-84. PMID 22924752 DOI: 10.1111/j.1471-4159.2012.07956.x  1
2012 Tarakanov AO, Fuxe KG, Borroto-Escuela DO. Integrin triplets of marine sponges in human D2 receptor heteromers. Journal of Receptor and Signal Transduction Research. 32: 202-8. PMID 22712841 DOI: 10.3109/10799893.2012.692119  1
2012 Fernández-Dueñas V, Llorente J, Gandía J, Borroto-Escuela DO, Agnati LF, Tasca CI, Fuxe K, Ciruela F. Fluorescence resonance energy transfer-based technologies in the study of protein-protein interactions at the cell surface. Methods (San Diego, Calif.). 57: 467-72. PMID 22683304 DOI: 10.1016/j.ymeth.2012.05.007  1
2012 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Diaz-Cabiale Z, Rivera A, Ferraro L, Tanganelli S, Tarakanov AO, Garriga P, Narváez JA, Ciruela F, Guescini M, Agnati LF. Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks. Frontiers in Physiology. 3: 136. PMID 22675301 DOI: 10.3389/fphys.2012.00136  1
2012 Ciruela F, Fernández-Dueñas V, Llorente J, Borroto-Escuela D, Cuffí ML, Carbonell L, Sánchez S, Agnati LF, Fuxe K, Tasca CI. G protein-coupled receptor oligomerization and brain integration: focus on adenosinergic transmission. Brain Research. 1476: 86-95. PMID 22575562 DOI: 10.1016/j.brainres.2012.04.056  1
2012 Tarakanov AO, Fuxe KG, Borroto-Escuela DO. Integrin triplets of marine sponges in human brain receptor heteromers. Journal of Molecular Neuroscience : Mn. 48: 154-60. PMID 22573093 DOI: 10.1007/s12031-012-9793-6  1
2012 Borroto-Escuela DO, Romero-Fernandez W, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Agnati LF, Ciruela F, Belluardo N, Fuxe K. The existence of FGFR1-5-HT1A receptor heterocomplexes in midbrain 5-HT neurons of the rat: relevance for neuroplasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6295-303. PMID 22553035 DOI: 10.1523/JNEUROSCI.4203-11.2012  1
2012 Agnati LF, Barlow P, Ghidoni R, Borroto-Escuela DO, Guidolin D, Fuxe K. Possible genetic and epigenetic links between human inner speech, schizophrenia and altruism. Brain Research. 1476: 38-57. PMID 22483963 DOI: 10.1016/j.brainres.2012.02.074  1
2012 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Ciruela F, Manger P, Leo G, Díaz-Cabiale Z, Agnati LF. On the role of volume transmission and receptor-receptor interactions in social behaviour: focus on central catecholamine and oxytocin neurons. Brain Research. 1476: 119-31. PMID 22373652 DOI: 10.1016/j.brainres.2012.01.062  1
2012 Fuxe K, Borroto-Escuela DO, Marcellino D, Romero-Fernandez W, Frankowska M, Guidolin D, Filip M, Ferraro L, Woods AS, Tarakanov A, Ciruela F, Agnati LF, Tanganelli S. GPCR heteromers and their allosteric receptor-receptor interactions. Current Medicinal Chemistry. 19: 356-63. PMID 22335512  1
2012 Guescini M, Leo G, Genedani S, Carone C, Pederzoli F, Ciruela F, Guidolin D, Stocchi V, Mantuano M, Borroto-Escuela DO, Fuxe K, Agnati LF. Microvesicle and tunneling nanotube mediated intercellular transfer of g-protein coupled receptors in cell cultures. Experimental Cell Research. 318: 603-13. PMID 22266577 DOI: 10.1016/j.yexcr.2012.01.005  1
2012 Tarakanov AO, Fuxe KG, Borroto-Escuela DO. On the origin of the triplet puzzle of homologies in receptor heteromers: Toll-like receptor triplets in different types of receptors. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 517-23. PMID 22068823 DOI: 10.1007/s00702-011-0734-2  1
2012 Borroto-Escuela DO, Romero-Fernandez W, Mudó G, Pérez-Alea M, Ciruela F, Tarakanov AO, Narvaez M, Di Liberto V, Agnati LF, Belluardo N, Fuxe K. Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity. Biological Psychiatry. 71: 84-91. PMID 22035699 DOI: 10.1016/j.biopsych.2011.09.012  1
2012 Borroto-Escuela DO, Agnati LF, Fuxe K, Ciruela F. Muscarinic acetylcholine receptor-interacting proteins (mAChRIPs): targeting the receptorsome. Current Drug Targets. 13: 53-71. PMID 22023407 DOI: 10.2174/138945012798868506  1
2012 Tarakanov AO, Fuxe KG, Borroto-Escuela DO. On the origin of the triplet puzzle of homologies in receptor heteromers: immunoglobulin triplets in different types of receptors. Journal of Molecular Neuroscience : Mn. 46: 616-21. PMID 21932037 DOI: 10.1007/s12031-011-9649-5  1
2011 Borroto-Escuela DO, Romero-Fernandez W, García-Negredo G, Correia PA, Garriga P, Fuxe K, Ciruela F. Dissecting the conserved NPxxY motif of the M3 muscarinic acetylcholine receptor: critical role of Asp-7.49 for receptor signaling and multiprotein complex formation. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 1009-22. PMID 22178951 DOI: 10.1159/000335788  1
2011 Romero-Fernandez W, Borroto-Escuela DO, Alea MP, Garcia-Mesa Y, Garriga P. Altered trafficking and unfolded protein response induction as a result of M3 muscarinic receptor impaired N-glycosylation. Glycobiology. 21: 1663-72. PMID 21798865 DOI: 10.1093/glycob/cwr105  1
2011 Alea MP, Borroto-Escuela DO, Romero-Fernandez W, Fuxe K, Garriga P. Differential expression of muscarinic acetylcholine receptor subtypes in Jurkat cells and their signaling. Journal of Neuroimmunology. 237: 13-22. PMID 21742386 DOI: 10.1016/j.jneuroim.2011.05.010  1
2011 Borroto-Escuela DO, Tarakanov AO, Guidolin D, Ciruela F, Agnati LF, Fuxe K. Moonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration. Iubmb Life. 63: 463-72. PMID 21698749 DOI: 10.1002/iub.473  1
2011 Romero-Fernandez W, Borroto-Escuela DO, Tarakanov AO, Mudó G, Narvaez M, Pérez-Alea M, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Agonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family. Biochemical and Biophysical Research Communications. 409: 764-8. PMID 21621521 DOI: 10.1016/j.bbrc.2011.05.085  1
2011 Romero-Fernandez W, Garriga P, Borroto-Escuela DO. Overproduction of human M₃ muscarinic acetylcholine receptor: an approach toward structural studies. Biotechnology Progress. 27: 838-45. PMID 21548142 DOI: 10.1002/btpr.615  1
2011 Van Craenenbroeck K, Borroto-Escuela DO, Romero-Fernandez W, Skieterska K, Rondou P, Lintermans B, Vanhoenacker P, Fuxe K, Ciruela F, Haegeman G. Dopamine D4 receptor oligomerization--contribution to receptor biogenesis. The Febs Journal. 278: 1333-44. PMID 21320289 DOI: 10.1111/j.1742-4658.2011.08052.x  1
2011 Ciruela F, Gómez-Soler M, Guidolin D, Borroto-Escuela DO, Agnati LF, Fuxe K, Fernández-Dueñas V. Adenosine receptor containing oligomers: their role in the control of dopamine and glutamate neurotransmission in the brain. Biochimica Et Biophysica Acta. 1808: 1245-55. PMID 21316336 DOI: 10.1016/j.bbamem.2011.02.007  1
2011 Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Ciruela F, Agnati LF, Fuxe K. On the existence of a possible A2A-D2-β-Arrestin2 complex: A2A agonist modulation of D2 agonist-induced β-arrestin2 recruitment. Journal of Molecular Biology. 406: 687-99. PMID 21256133 DOI: 10.1016/j.jmb.2011.01.022  1
2011 Borroto-Escuela DO, Van Craenenbroeck K, Romero-Fernandez W, Guidolin D, Woods AS, Rivera A, Haegeman G, Agnati LF, Tarakanov AO, Fuxe K. Dopamine D2 and D4 receptor heteromerization and its allosteric receptor-receptor interactions. Biochemical and Biophysical Research Communications. 404: 928-34. PMID 21184734 DOI: 10.1016/j.bbrc.2010.12.083  1
2011 Borroto-Escuela DO, Correia PA, Romero-Fernandez W, Narvaez M, Fuxe K, Ciruela F, Garriga P. Muscarinic receptor family interacting proteins: role in receptor function. Journal of Neuroscience Methods. 195: 161-9. PMID 21134400 DOI: 10.1016/j.jneumeth.2010.11.025  1
2010 Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Gómez-Soler M, Corrales F, Marcellino D, Narvaez M, Frankowska M, Flajolet M, Heintz N, Agnati LF, Ciruela F, Fuxe K. Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices. Biochemical and Biophysical Research Communications. 402: 801-7. PMID 21040702 DOI: 10.1016/j.bbrc.2010.10.122  1
2010 Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Marcellino D, Ciruela F, Agnati LF, Fuxe K. Dopamine D2 and 5-hydroxytryptamine 5-HT(â‚‚A) receptors assemble into functionally interacting heteromers. Biochemical and Biophysical Research Communications. 401: 605-10. PMID 20888323 DOI: 10.1016/j.bbrc.2010.09.110  1
2010 Ciruela F, Vallano A, Arnau JM, Sánchez S, Borroto-Escuela DO, Agnati LF, Fuxe K, Fernández-Dueñas V. G protein-coupled receptor oligomerization for what? Journal of Receptor and Signal Transduction Research. 30: 322-30. PMID 20718634 DOI: 10.3109/10799893.2010.508166  1
2010 Fuxe K, Marcellino D, Borroto-Escuela DO, Frankowska M, Ferraro L, Guidolin D, Ciruela F, Agnati LF. The changing world of G protein-coupled receptors: from monomers to dimers and receptor mosaics with allosteric receptor-receptor interactions. Journal of Receptor and Signal Transduction Research. 30: 272-83. PMID 20684666 DOI: 10.3109/10799893.2010.506191  1
2010 Borroto-Escuela DO, García-Negredo G, Garriga P, Fuxe K, Ciruela F. The M(5) muscarinic acetylcholine receptor third intracellular loop regulates receptor function and oligomerization. Biochimica Et Biophysica Acta. 1803: 813-25. PMID 20398705 DOI: 10.1016/j.bbamcr.2010.04.002  1
2010 Fuxe K, Marcellino D, Borroto-Escuela DO, Guescini M, Fernández-Dueñas V, Tanganelli S, Rivera A, Ciruela F, Agnati LF. Adenosine-dopamine interactions in the pathophysiology and treatment of CNS disorders. Cns Neuroscience & Therapeutics. 16: e18-42. PMID 20345970 DOI: 10.1111/j.1755-5949.2009.00126.x  1
2010 Borroto-Escuela DO, Correia PA, Perez Alea M, Narvaez M, Garriga P, Fuxe K, Ciruela F. Impaired M(3) muscarinic acetylcholine receptor signal transduction through blockade of binding of multiple proteins to its third intracellular loop. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 25: 397-408. PMID 20332620 DOI: 10.1159/000303044  1
2010 Borroto-Escuela DO, Marcellino D, Narvaez M, Flajolet M, Heintz N, Agnati L, Ciruela F, Fuxe K. A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R. Biochemical and Biophysical Research Communications. 394: 222-7. PMID 20197060 DOI: 10.1016/j.bbrc.2010.02.168  1
2010 Borroto-Escuela DO, Narvaez M, Marcellino D, Parrado C, Narvaez JA, Tarakanov AO, Agnati LF, Díaz-Cabiale Z, Fuxe K. Galanin receptor-1 modulates 5-hydroxtryptamine-1A signaling via heterodimerization. Biochemical and Biophysical Research Communications. 393: 767-72. PMID 20171159 DOI: 10.1016/j.bbrc.2010.02.078  1
2006 Borroto Escuela DO, Perez Alea M, Fernandez WR, Gil DB. Vectors and P64k gene targeting for tandem affinity purification in Neisseria meningitidis. Journal of Microbiological Methods. 65: 187-93. PMID 16169105 DOI: 10.1016/j.mimet.2005.07.013  0.64
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