Edward S. Lein - Publications

Affiliations: 
Allen Institute for Brain Science, Seattle, WA, United States 
Area:
Gene expression

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Bakken TE, Miller JA, Ding SL, Sunkin SM, Smith KA, Ng L, Szafer A, Dalley RA, Royall JJ, Lemon T, Shapouri S, Aiona K, Arnold J, Bennett JL, Bertagnolli D, ... ... Lein ES, et al. A comprehensive transcriptional map of primate brain development. Nature. PMID 27409810 DOI: 10.1038/nature18637  0.52
2016 Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, ... ... Lein ES, et al. Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons. Nature Protocols. 11: 499-524. PMID 26890679 DOI: 10.1038/nprot.2016.015  1
2015 Hawrylycz M, Miller JA, Menon V, Feng D, Dolbeare T, Guillozet-Bongaarts AL, Jegga AG, Aronow BJ, Lee CK, Bernard A, Glasser MF, Dierker DL, Menche J, Szafer A, Collman F, ... ... Lein E, et al. Canonical genetic signatures of the adult human brain. Nature Neuroscience. PMID 26571460 DOI: 10.1038/nn.4171  1
2015 Bakken TE, Miller JA, Luo R, Bernard A, Bennett JL, Lee CK, Bertagnolli D, Parikshak NN, Smith KA, Sunkin SM, Amaral DG, Geschwind DH, Lein ES. Spatiotemporal dynamics of the postnatal developing primate brain transcriptome. Human Molecular Genetics. 24: 4327-39. PMID 25954031 DOI: 10.1093/hmg/ddv166  0.36
2015 Rossier J, Bernard A, Cabungcal JH, Perrenoud Q, Savoye A, Gallopin T, Hawrylycz M, Cuénod M, Do K, Urban A, Lein ES. Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin. Molecular Psychiatry. 20: 154-61. PMID 25510509 DOI: 10.1038/mp.2014.162  1
2015 Ouyang A, Jeon T, Sunkin SM, Pletikos M, Sedmak G, Sestan N, Lein ES, Huang H. Spatial mapping of structural and connectional imaging data for the developing human brain with diffusion tensor imaging. Methods (San Diego, Calif.). 73: 27-37. PMID 25448302 DOI: 10.1016/j.ymeth.2014.10.025  1
2015 Sorensen SA, Bernard A, Menon V, Royall JJ, Glattfelder KJ, Desta T, Hirokawa K, Mortrud M, Miller JA, Zeng H, Hohmann JG, Jones AR, Lein ES. Correlated gene expression and target specificity demonstrate excitatory projection neuron diversity. Cerebral Cortex (New York, N.Y. : 1991). 25: 433-49. PMID 24014670 DOI: 10.1093/cercor/bht243  1
2014 Pfenning AR, Hara E, Whitney O, Rivas MV, Wang R, Roulhac PL, Howard JT, Wirthlin M, Lovell PV, Ganapathy G, Mouncastle J, Moseley MA, Thompson JW, Soderblom EJ, Iriki A, ... ... Lein E, et al. Convergent transcriptional specializations in the brains of humans and song-learning birds. Science (New York, N.Y.). 346: 1256846. PMID 25504733 DOI: 10.1126/science.1256846  1
2014 Lee FS, Heimer H, Giedd JN, Lein ES, Šestan N, Weinberger DR, Casey BJ. Mental health. Adolescent mental health--opportunity and obligation. Science (New York, N.Y.). 346: 547-9. PMID 25359951 DOI: 10.1126/science.1260497  1
2014 Strange BA, Witter MP, Lein ES, Moser EI. Functional organization of the hippocampal longitudinal axis. Nature Reviews. Neuroscience. 15: 655-69. PMID 25234264 DOI: 10.1038/nrn3785  1
2014 Bernier R, Golzio C, Xiong B, Stessman HA, Coe BP, Penn O, Witherspoon K, Gerdts J, Baker C, Vulto-van Silfhout AT, Schuurs-Hoeijmakers JH, Fichera M, Bosco P, Buono S, Alberti A, ... ... Lein E, et al. Disruptive CHD8 mutations define a subtype of autism early in development. Cell. 158: 263-76. PMID 24998929 DOI: 10.1016/j.cell.2014.06.017  1
2014 Molnár Z, Kaas JH, de Carlos JA, Hevner RF, Lein E, NÄ›mec P. Evolution and development of the mammalian cerebral cortex. Brain, Behavior and Evolution. 83: 126-39. PMID 24776993 DOI: 10.1159/000357753  1
2014 Lein E, Hawrylycz M. The genetic geography of the brain Scientific American. 310: 70-77. PMID 24712126 DOI: 10.1038/scientificamerican0414-70  1
2014 Miller JA, Ding SL, Sunkin SM, Smith KA, Ng L, Szafer A, Ebbert A, Riley ZL, Royall JJ, Aiona K, Arnold JM, Bennet C, Bertagnolli D, Brouner K, Butler S, ... ... Lein ES, et al. Transcriptional landscape of the prenatal human brain. Nature. 508: 199-206. PMID 24695229 DOI: 10.1038/nature13185  1
2014 Stoner R, Chow ML, Boyle MP, Sunkin SM, Mouton PR, Roy S, Wynshaw-Boris A, Colamarino SA, Lein ES, Courchesne E. Patches of disorganization in the neocortex of children with autism. The New England Journal of Medicine. 370: 1209-19. PMID 24670167 DOI: 10.1056/NEJMoa1307491  1
2014 Miller JA, Menon V, Goldy J, Kaykas A, Lee CK, Smith KA, Shen EH, Phillips JW, Lein ES, Hawrylycz MJ. Improving reliability and absolute quantification of human brain microarray data by filtering and scaling probes using RNA-Seq. Bmc Genomics. 15: 154. PMID 24564186 DOI: 10.1186/1471-2164-15-154  1
2014 Prüfer K, Racimo F, Patterson N, Jay F, Sankararaman S, Sawyer S, Heinze A, Renaud G, Sudmant PH, de Filippo C, Li H, Mallick S, Dannemann M, Fu Q, Kircher M, ... ... Lein ES, et al. The complete genome sequence of a Neanderthal from the Altai Mountains. Nature. 505: 43-9. PMID 24352235 DOI: 10.1038/nature12886  1
2013 Willsey AJ, Sanders SJ, Li M, Dong S, Tebbenkamp AT, Muhle RA, Reilly SK, Lin L, Fertuzinhos S, Miller JA, Murtha MT, Bichsel C, Niu W, Cotney J, Ercan-Sencicek AG, ... ... Lein ES, et al. Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell. 155: 997-1007. PMID 24267886 DOI: 10.1016/j.cell.2013.10.020  1
2013 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Å estan N, ... ... Lein ES, et al. Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development (Cambridge, England). 140: 4633-44. PMID 24154525 DOI: 10.1242/dev.097212  1
2012 Hawrylycz MJ, Lein ES, Guillozet-Bongaarts AL, Shen EH, Ng L, Miller JA, van de Lagemaat LN, Smith KA, Ebbert A, Riley ZL, Abajian C, Beckmann CF, Bernard A, Bertagnolli D, Boe AF, et al. An anatomically comprehensive atlas of the adult human brain transcriptome. Nature. 489: 391-9. PMID 22996553 DOI: 10.1038/nature11405  1
2012 Zeng H, Shen EH, Hohmann JG, Oh SW, Bernard A, Royall JJ, Glattfelder KJ, Sunkin SM, Morris JA, Guillozet-Bongaarts AL, Smith KA, Ebbert AJ, Swanson B, Kuan L, Page DT, ... ... Lein ES, et al. Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures. Cell. 149: 483-96. PMID 22500809 DOI: 10.1016/j.cell.2012.02.052  1
2012 Bernard A, Lubbers LS, Tanis KQ, Luo R, Podtelezhnikov AA, Finney EM, McWhorter MM, Serikawa K, Lemon T, Morgan R, Copeland C, Smith K, Cullen V, Davis-Turak J, Lee CK, ... ... Lein ES, et al. Transcriptional architecture of the primate neocortex. Neuron. 73: 1083-99. PMID 22445337 DOI: 10.1016/j.neuron.2012.03.002  1
2011 Hofer SB, Ko H, Pichler B, Vogelstein J, Ros H, Zeng H, Lein E, Lesica NA, Mrsic-Flogel TD. Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex. Nature Neuroscience. 14: 1045-52. PMID 21765421 DOI: 10.1038/nn.2876  1
2011 Hawrylycz M, Ng L, Page D, Morris J, Lau C, Faber S, Faber V, Sunkin S, Menon V, Lein E, Jones A. Multi-scale correlation structure of gene expression in the brain. Neural Networks : the Official Journal of the International Neural Network Society. 24: 933-42. PMID 21764550 DOI: 10.1016/j.neunet.2011.06.012  1
2011 Boyle MP, Bernard A, Thompson CL, Ng L, Boe A, Mortrud M, Hawrylycz MJ, Jones AR, Hevner RF, Lein ES. Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. The Journal of Comparative Neurology. 519: 2061-89. PMID 21491433 DOI: 10.1002/cne.22655  1
2011 Lin D, Boyle MP, Dollar P, Lee H, Lein ES, Perona P, Anderson DJ. Functional identification of an aggression locus in the mouse hypothalamus. Nature. 470: 221-6. PMID 21307935 DOI: 10.1038/nature09736  1
2011 Zariwala HA, Madisen L, Ahrens KF, Bernard A, Lein ES, Jones AR, Zeng H. Visual tuning properties of genetically identified layer 2/3 neuronal types in the primary visual cortex of cre-transgenic mice. Frontiers in Systems Neuroscience. 4: 162. PMID 21283555 DOI: 10.3389/fnsys.2010.00162  1
2011 Zariwala HA, Madisen L, Ahrens KF, Bernard A, Lein ES, Jones AR, Zeng H. Visual tuning properties of genetically identified layer 2/3 neuronal types in the primary visual cortex of Cre-transgenic mice Frontiers in Systems Neuroscience 1
2010 Thompson CL, Wisor JP, Lee CK, Pathak SD, Gerashchenko D, Smith KA, Fischer SR, Kuan CL, Sunkin SM, Ng LL, Lau C, Hawrylycz M, Jones AR, Kilduff TS, Lein ES. Molecular and anatomical signatures of sleep deprivation in the mouse brain. Frontiers in Neuroscience. 4: 165. PMID 21088695 DOI: 10.3389/fnins.2010.00165  1
2010 Morris JA, Royall JJ, Bertagnolli D, Boe AF, Burnell JJ, Byrnes EJ, Copeland C, Desta T, Fischer SR, Goldy J, Glattfelder KJ, Kidney JM, Lemon T, Orta GJ, Parry SE, ... ... Lein ES, et al. Divergent and nonuniform gene expression patterns in mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 19049-54. PMID 20956311 DOI: 10.1073/pnas.1003732107  1
2010 Madisen L, Zwingman TA, Sunkin SM, Oh SW, Zariwala HA, Gu H, Ng LL, Palmiter RD, Hawrylycz MJ, Jones AR, Lein ES, Zeng H. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nature Neuroscience. 13: 133-40. PMID 20023653 DOI: 10.1038/nn.2467  1
2010 Ng L, Lau C, Sunkin SM, Bernard A, Chakravarty MM, Lein ES, Jones AR, Hawrylycz M. Surface-based mapping of gene expression and probabilistic expression maps in the mouse cortex. Methods (San Diego, Calif.). 50: 55-62. PMID 19818854 DOI: 10.1016/j.ymeth.2009.10.001  1
2010 Hawrylycz M, Bernard A, Lau C, Sunkin SM, Chakravarty MM, Lein ES, Jones AR, Ng L. Areal and laminar differentiation in the mouse neocortex using large scale gene expression data. Methods (San Diego, Calif.). 50: 113-21. PMID 19800006 DOI: 10.1016/j.ymeth.2009.09.005  1
2010 Thompson CL, Lein ES. Hippocampus: Molecular Anatomy Encyclopedia of Neuroscience. 1143-1148. DOI: 10.1016/B978-008045046-9.01811-8  1
2009 Bernard A, Sorensen SA, Lein ES. Shifting the paradigm: new approaches for characterizing and classifying neurons. Current Opinion in Neurobiology. 19: 530-6. PMID 19896835 DOI: 10.1016/j.conb.2009.09.010  1
2009 Ng L, Bernard A, Lau C, Overly CC, Dong HW, Kuan C, Pathak S, Sunkin SM, Dang C, Bohland JW, Bokil H, Mitra PP, Puelles L, Hohmann J, Anderson DJ, ... Lein ES, et al. An anatomic gene expression atlas of the adult mouse brain. Nature Neuroscience. 12: 356-62. PMID 19219037 DOI: 10.1038/nn.2281  1
2009 Pathak SD, Haynorb DR, Thompson CL, Lein E, Hawrylycz M. Gene expression based mouse brain parcellation using Markov random field regularized non-negative matrix factorization Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7262. DOI: 10.1117/12.813437  1
2008 Thompson CL, Pathak SD, Jeromin A, Ng LL, MacPherson CR, Mortrud MT, Cusick A, Riley ZL, Sunkin SM, Bernard A, Puchalski RB, Gage FH, Jones AR, Bajic VB, Hawrylycz MJ, ... Lein ES, et al. Genomic anatomy of the hippocampus. Neuron. 60: 1010-21. PMID 19109908 DOI: 10.1016/j.neuron.2008.12.008  1
2008 Kilduff TS, Lein ES, de la Iglesia H, Sakurai T, Fu YH, Shaw P. New developments in sleep research: molecular genetics, gene expression, and systems neurobiology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11814-8. PMID 19005045 DOI: 10.1523/JNEUROSCI.3768-08.2008  1
2008 Wisor JP, Pasumarthi RK, Gerashchenko D, Thompson CL, Pathak S, Sancar A, Franken P, Lein ES, Kilduff TS. Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7193-201. PMID 18614689 DOI: 10.1523/JNEUROSCI.1150-08.2008  1
2008 Lee CK, Sunkin SM, Kuan C, Thompson CL, Pathak S, Ng L, Lau C, Fischer S, Mortrud M, Slaughterbeck C, Jones A, Lein E, Hawrylycz M. Quantitative methods for genome-scale analysis of in situ hybridization and correlation with microarray data. Genome Biology. 9: R23. PMID 18234097 DOI: 10.1186/gb-2008-9-1-r23  1
2008 Wisor JP, Pasumarthi RK, Gerashchenko D, Thompson CL, Pathak S, Sancar A, Franken P, Lein ES, Kilduff TS. Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains (Journal of Neuroscience (July 9, 2008) (7193-7201)) Journal of Neuroscience. 28: 7929.  1
2007 Ng L, Pathak SD, Kuan C, Lau C, Dong H, Sodt A, Dang C, Avants B, Yushkevich P, Gee JC, Haynor D, Lein E, Jones A, Hawrylycz M. Neuroinformatics for genome-wide 3D gene expression mapping in the mouse brain Ieee/Acm Transactions On Computational Biology and Bioinformatics. 4: 382-392. PMID 17666758 DOI: 10.1109/TCBB.2007.1035  1
2007 Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, Bernard A, Boe AF, Boguski MS, Brockway KS, Byrnes EJ, Chen L, Chen L, Chen TM, Chin MC, Chong J, et al. Genome-wide atlas of gene expression in the adult mouse brain. Nature. 445: 168-76. PMID 17151600 DOI: 10.1038/nature05453  1
2006 Tan EM, Yamaguchi Y, Horwitz GD, Gosgnach S, Lein ES, Goulding M, Albright TD, Callaway EM. Selective and quickly reversible inactivation of mammalian neurons in vivo using the Drosophila allatostatin receptor. Neuron. 51: 157-70. PMID 16846851 DOI: 10.1016/j.neuron.2006.06.018  1
2005 Lie DC, Colamarino SA, Song HJ, Désiré L, Mira H, Consiglio A, Lein ES, Jessberger S, Lansford H, Dearie AR, Gage FH. Wnt signalling regulates adult hippocampal neurogenesis. Nature. 437: 1370-5. PMID 16251967 DOI: 10.1038/nature04108  1
2005 Lein ES, Callaway EM, Albright TD, Gage FH. Redefining the boundaries of the hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional reconstruction. The Journal of Comparative Neurology. 485: 1-10. PMID 15776443 DOI: 10.1002/cne.20426  1
2005 Pathak S, Lein E, Smith S, Haynor DR, Hawrylycz M. Gene expression detection and expression visualization in in-situ hybridized cross-sectional images of the mouse brain Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5747: 1112-1119. DOI: 10.1117/12.594722  1
2004 Lein ES, Zhao X, Gage FH. Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3879-89. PMID 15084669 DOI: 10.1523/JNEUROSCI.4710-03.2004  1
2003 Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee KF, Gage FH. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. 100: 6777-82. PMID 12748381 DOI: 10.1073/pnas.1131928100  1
2002 Lechner HA, Lein ES, Callaway EM. A genetic method for selective and quickly reversible silencing of Mammalian neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5287-90. PMID 12097479  1
2001 Zhao X, Lein ES, He A, Smith SC, Aston C, Gage FH. Transcriptional profiling reveals strict boundaries between hippocampal subregions. The Journal of Comparative Neurology. 441: 187-96. PMID 11745644 DOI: 10.1002/cne.1406  1
2001 Lee E, Lein ES, Firestone GL. Tissue-specific expression of the transcriptionally regulated serum and glucocorticoid-inducible protein kinase (Sgk) during mouse embryogenesis. Mechanisms of Development. 103: 177-81. PMID 11335130 DOI: 10.1016/S0925-4773(01)00351-3  1
2000 Lein ES, Hohn A, Shatz CJ. Dynamic regulation of BDNF and NT-3 expression during visual system development. The Journal of Comparative Neurology. 420: 1-18. PMID 10745216 DOI: 10.1002/(SICI)1096-9861(20000424)420:1<1::AID-CNE1>3.0.CO;2-H  1
2000 Lein ES, Shatz CJ. Rapid regulation of brain-derived neurotrophic factor mRNA within eye-specific circuits during ocular dominance column formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 1470-83. PMID 10662837  1
1999 Lein ES, Finney EM, McQuillen PS, Shatz CJ. Subplate neuron ablation alters neurotrophin expression and ocular dominance column formation. Proceedings of the National Academy of Sciences of the United States of America. 96: 13491-5. PMID 10557348 DOI: 10.1073/pnas.96.23.13491  1
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