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Travis T. Denton, Ph.D. - Publications

Affiliations: 
2002 University of Montana, Missoula, MT 
Area:
Organic Chemistry, Pharmaceutical Chemistry, Biochemistry
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11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Shen D, Kruger L, Deatherage T, Denton TT. Synthesis of α-Ketoglutaramic acid. Analytical Biochemistry. 113862. PMID 32771374 DOI: 10.1016/J.Ab.2020.113862  0.309
2016 Banerjee K, Munshi S, Xu H, Frank DE, Chen HL, Chu CT, Yang J, Cho S, Kagan VE, Denton TT, Tyurina YY, Jiang JF, Gibson GE. Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease. Neurochemistry International. PMID 26923918 DOI: 10.1016/J.Neuint.2016.02.011  0.307
2015 Gibson GE, Xu H, Chen HL, Chen W, Denton TT, Zhang S. Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines. Journal of Neurochemistry. 134: 86-96. PMID 25772995 DOI: 10.1111/Jnc.13096  0.317
2015 Hensley K, Denton TT. Alternative functions of the brain transsulfuration pathway represent an underappreciated aspect of brain redox biochemistry with significant potential for therapeutic engagement. Free Radical Biology & Medicine. 78: 123-34. PMID 25463282 DOI: 10.1016/J.Freeradbiomed.2014.10.581  0.31
2015 Bobango J, Denton TT, Talley TT. A survey of high resolution AChBP X-ray structures reveals details of tertiary and quaternary movements of the protein, both real and imagined, upon ligand binding Biochemical Pharmacology. 97: 628. DOI: 10.1016/J.Bcp.2015.08.022  0.546
2006 Yano JK, Denton TT, Cerny MA, Zhang X, Johnson EF, Cashman JR. Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization. Journal of Medicinal Chemistry. 49: 6987-7001. PMID 17125252 DOI: 10.1021/Jm060519R  0.33
2006 Santos SS, Gibson GE, Cooper AJ, Denton TT, Thompson CM, Bunik VI, Alves PM, Sonnewald U. Inhibitors of the alpha-ketoglutarate dehydrogenase complex alter [1-13C]glucose and [U-13C]glutamate metabolism in cerebellar granule neurons. Journal of Neuroscience Research. 83: 450-8. PMID 16416424 DOI: 10.1002/Jnr.20749  0.499
2005 Bunik VI, Denton TT, Xu H, Thompson CM, Cooper AJ, Gibson GE. Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells. Biochemistry. 44: 10552-61. PMID 16060664 DOI: 10.1021/Bi0503100  0.503
2005 Denton TT, Zhang X, Cashman JR. 5-substituted, 6-substituted, and unsubstituted 3-heteroaromatic pyridine analogues of nicotine as selective inhibitors of cytochrome P-450 2A6. Journal of Medicinal Chemistry. 48: 224-39. PMID 15634016 DOI: 10.1021/Jm049696N  0.312
2002 Denton T, Seib T, Bridges R, Thompson C. Synthesis and preliminary evaluation of trans-3,4-conformationally-restricted glutamate and pyroglutamate analogues as novel EAAT2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 12: 3209-13. PMID 12372536 DOI: 10.1016/S0960-894X(02)00520-6  0.474
2001 Denton TT, Thompson CM, Cooper AJ. Analysis of conformationally restricted alpha-ketoglutarate analogues as substrates of dehydrogenases and aminotransferases. Analytical Biochemistry. 298: 265-74. PMID 11700982 DOI: 10.1006/Abio.2001.5366  0.499
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