R Andrew Tasker - Publications

Biomedical Sciences UPEI, Charlottetown, Prince Edward Island, Canada 
neurodegeneration, excitatory amino acids, neurotoxicology, behaviour, epilepsy, stroke

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hume AW, Tasker RA. Endothelin-1-Induced Ischemic Damage and Functional Impairment Is Mediated Primarily by NR2B-Containing NMDA Receptors. Neurotoxicity Research. PMID 31797304 DOI: 10.1007/s12640-019-00138-3  0.76
2019 Happ DF, Wegener G, Tasker RA. Effect of ischemic lesions in medial prefrontal cortex and nucleus accumbens on affective behavior in rats. Behavioural Brain Research. 112234. PMID 31521735 DOI: 10.1016/j.bbr.2019.112234  1
2017 Happ DF, Tasker RA. Effects of α7 Nicotinic Receptor Activation on Cell Survival in Rat Organotypic Hippocampal Slice Cultures. Neurotoxicity Research. PMID 29273965 DOI: 10.1007/s12640-017-9854-2  1
2017 Déziel RA, Tasker RA. Bilateral ischaemic lesions of the medial prefrontal cortex are anxiogenic in the rat. Acta Neuropsychiatrica. 1-6. PMID 29202895 DOI: 10.1017/neu.2017.32  0.76
2017 Bernard PB, Ramsay LA, MacDonald DS, Tasker RA. Progressive changes in hippocampal cytoarchitecture in a neurodevelopmental rat model of epilepsy: implications for understanding presymptomatic epileptogenesis, predictive diagnosis, and targeted treatments. The Epma Journal. 8: 247-254. PMID 29021835 DOI: 10.1007/s13167-017-0111-9  1
2016 Déziel RA, Tasker RA. Effects of Endothelin-Induced Prefrontal Cortical Lesions on Delay Discounting in the Rat. Behavioral Neuroscience. PMID 28004949 DOI: 10.1037/bne0000179  0.76
2016 Thomsen MB, Lillethorup TP, Jakobsen S, Nielsen EH, Simonsen M, Wegener G, Landau AM, Tasker RA. Neonatal domoic acid alters in vivo binding of [(11)C]yohimbine to α2-adrenoceptors in adult rat brain. Psychopharmacology. PMID 27557950 DOI: 10.1007/s00213-016-4416-5  1
2016 Happ DF, Tasker RA. A method for objectively quantifying propidium iodide exclusion in organotypic hippocampal slice cultures. Journal of Neuroscience Methods. 269: 1-5. PMID 27179931 DOI: 10.1016/j.jneumeth.2016.05.006  1
2015 Marriott AL, Tasker RA, Ryan CL, Doucette TA. Alterations to prepulse inhibition magnitude and latency in adult rats following neonatal treatment with domoic acid and social isolation rearing. Behavioural Brain Research. PMID 26590368 DOI: 10.1016/j.bbr.2015.11.009  1
2015 Marriott AL, Rojas-Mancilla E, Morales P, Herrera-Marschitz M, Tasker RA. Models of progressive neurological dysfunction originating early in life. Progress in Neurobiology. PMID 26483068 DOI: 10.1016/j.pneurobio.2015.10.001  1
2015 Déziel RA, Ryan CL, Tasker RA. Ischemic lesions localized to the medial prefrontal cortex produce selective deficits in measures of executive function in rats. Behavioural Brain Research. 293: 54-61. PMID 26166190 DOI: 10.1016/j.bbr.2015.07.003  1
2014 Marriott AL, Tasker RA, Ryan CL, Doucette TA. Neonatal domoic acid abolishes latent inhibition in male but not female rats and has differential interactions with social isolation. Neuroscience Letters. 578: 22-6. PMID 24954074 DOI: 10.1016/j.neulet.2014.06.025  1
2014 Livingston-Thomas JM, McGuire EP, Doucette TA, Tasker RA. Voluntary forced use of the impaired limb following stroke facilitates functional recovery in the rat. Behavioural Brain Research. 261: 210-9. PMID 24388978 DOI: 10.1016/j.bbr.2013.12.032  1
2014 Pérez-Gómez A, Tasker RA. Enhanced mossy fiber sprouting and synapse formation in organotypic hippocampal cultures following transient domoic acid excitotoxicity. Neurotoxicity Research. 25: 402-10. PMID 24347374 DOI: 10.1007/s12640-013-9450-z  1
2013 Pérez-Gómez A, Tasker RA. Transient domoic acid excitotoxicity increases BDNF expression and activates both MEK- and PKA-dependent neurogenesis in organotypic hippocampal slices. Bmc Neuroscience. 14: 72. PMID 23865384 DOI: 10.1186/1471-2202-14-72  1
2013 Livingston-Thomas JM, Tasker RA. Animal models of post-ischemic forced use rehabilitation: methods, considerations, and limitations. Experimental & Translational Stroke Medicine. 5: 2. PMID 23343500 DOI: 10.1186/2040-7378-5-2  1
2013 Livingston-Thomas JM, Hume AW, Doucette TA, Tasker RA. A novel approach to induction and rehabilitation of deficits in forelimb function in a rat model of ischemic stroke. Acta Pharmacologica Sinica. 34: 104-12. PMID 23103624 DOI: 10.1038/aps.2012.106  1
2012 Gill DA, Perry MA, McGuire EP, Pérez-Gómez A, Tasker RA. Low-dose neonatal domoic acid causes persistent changes in behavioural and molecular indicators of stress response in rats. Behavioural Brain Research. 230: 409-17. PMID 22387806 DOI: 10.1016/j.bbr.2012.02.036  1
2012 Pérez-Gómez A, Tasker RA. Enhanced neurogenesis in organotypic cultures of rat hippocampus after transient subfield-selective excitotoxic insult induced by domoic acid. Neuroscience. 208: 97-108. PMID 22366222 DOI: 10.1016/j.neuroscience.2012.02.003  1
2011 Kjaer SL, Hougaard KS, Tasker RA, MacDonald DS, Rosenberg R, Elfving B, Wegener G. Influence of diurnal phase on startle response in adult rats exposed to dexamethasone in utero. Physiology & Behavior. 102: 444-52. PMID 21172366 DOI: 10.1016/j.physbeh.2010.12.015  1
2011 Herrera-Marschitz M, Morales P, Leyton L, Bustamante D, Klawitter V, Espina-Marchant P, Allende C, Lisboa F, Cunich G, Jara-Cavieres A, Neira T, Gutierrez-Hernandez MA, Gonzalez-Lira V, Simola N, Schmitt A, et al. Perinatal asphyxia: current status and approaches towards neuroprotective strategies, with focus on sentinel proteins. Neurotoxicity Research. 19: 603-27. PMID 20645042 DOI: 10.1007/s12640-010-9208-9  1
2011 Fatehi-Hassanabad Z, Tasker RA. Peroxisome proliferator-activated receptor-γ (PPAR-γ) activation confers functional neuroprotection in global ischemia. Neurotoxicity Research. 19: 462-71. PMID 20524105 DOI: 10.1007/s12640-010-9201-3  1
2010 Tasker RA, Adams-Marriott AL, Shaw CA. New animal models of progressive neurodegeneration: tools for identifying targets in predictive diagnostics and presymptomatic treatment. The Epma Journal. 1: 217-27. PMID 23199060 DOI: 10.1007/s13167-010-0019-0  1
2010 Gill DA, Bastlund JF, Watson WP, Ryan CL, Reynolds DS, Tasker RA. Neonatal exposure to low-dose domoic acid lowers seizure threshold in adult rats. Neuroscience. 169: 1789-99. PMID 20600646 DOI: 10.1016/j.neuroscience.2010.06.045  1
2010 Gill DA, Ramsay SL, Tasker RA. Selective reductions in subpopulations of GABAergic neurons in a developmental rat model of epilepsy. Brain Research. 1331: 114-23. PMID 20331981 DOI: 10.1016/j.brainres.2010.03.054  1
2010 Morales P, Simola N, Bustamante D, Lisboa F, Fiedler J, Gebicke-Haerter PJ, Morelli M, Tasker RA, Herrera-Marschitz M. Nicotinamide prevents the long-term effects of perinatal asphyxia on apoptosis, non-spatial working memory and anxiety in rats. Experimental Brain Research. 202: 1-14. PMID 20012537 DOI: 10.1007/s00221-009-2103-z  1
2009 Gill DA, Bastlund JF, Anderson NJ, Tasker RA. Reductions in paradoxical sleep time in adult rats treated neonatally with low dose domoic acid. Behavioural Brain Research. 205: 564-7. PMID 19631692 DOI: 10.1016/j.bbr.2009.07.018  1
2009 Perry MA, Ryan CL, Tasker RA. Effects of low dose neonatal domoic acid administration on behavioural and physiological response to mild stress in adult rats. Physiology & Behavior. 98: 53-9. PMID 19375434 DOI: 10.1016/j.physbeh.2009.04.009  1
2008 Sun HS, Doucette TA, Liu Y, Fang Y, Teves L, Aarts M, Ryan CL, Bernard PB, Lau A, Forder JP, Salter MW, Wang YT, Tasker RA, Tymianski M. Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat. Stroke; a Journal of Cerebral Circulation. 39: 2544-53. PMID 18617669 DOI: 10.1161/STROKEAHA.107.506048  1
2007 Cui H, Hayashi A, Sun HS, Belmares MP, Cobey C, Phan T, Schweizer J, Salter MW, Wang YT, Tasker RA, Garman D, Rabinowitz J, Lu PS, Tymianski M. PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9901-15. PMID 17855605 DOI: 10.1523/JNEUROSCI.1464-07.2007  1
2007 Bernard PB, Macdonald DS, Gill DA, Ryan CL, Tasker RA. Hippocampal mossy fiber sprouting and elevated trkB receptor expression following systemic administration of low dose domoic acid during neonatal development. Hippocampus. 17: 1121-33. PMID 17636548 DOI: 10.1002/hipo.20342  1
2007 Novelli A, Tasker RA. Excitatory amino acids in epilepsy: from the clinics to the laboratory. Amino Acids. 32: 295-7. PMID 17393261 DOI: 10.1007/s00726-006-0413-z  1
2007 Doucette TA, Ryan CL, Tasker RA. Gender-based changes in cognition and emotionality in a new rat model of epilepsy. Amino Acids. 32: 317-22. PMID 17068662 DOI: 10.1007/s00726-006-0418-7  1
2006 Ryan CL, Doucette TA, Gill DA, Langdon KD, Liu Y, Perry MA, Tasker RA. An improved post-operative care protocol allows detection of long-term functional deficits following MCAo surgery in rats. Journal of Neuroscience Methods. 154: 30-7. PMID 16423407 DOI: 10.1016/j.jneumeth.2005.11.009  1
2005 Tasker RA, Perry MA, Doucette TA, Ryan CL. NMDA receptor involvement in the effects of low dose domoic acid in neonatal rats. Amino Acids. 28: 193-6. PMID 15714252 DOI: 10.1007/s00726-005-0167-z  1
2005 Novelli A, Tasker RAR. Introduction: Signaling in neurodegeneration (Chapter 2) Amino Acids. 28: 165-167. DOI: 10.1007/s00726-005-0163-3  1
2004 Doucette TA, Bernard PB, Husum H, Perry MA, Ryan CL, Tasker RA. Low doses of domoic acid during postnatal development produce permanent changes in rat behaviour and hippocampal morphology. Neurotoxicity Research. 6: 555-63. PMID 15639787 DOI: 10.1007/BF03033451  1
2003 Doucette TA, Bernard PB, Yuill PC, Tasker RA, Ryan CL. Low doses of non-NMDA glutamate receptor agonists alter neurobehavioural development in the rat. Neurotoxicology and Teratology. 25: 473-9. PMID 12798964 DOI: 10.1016/S0892-0362(03)00034-5  1
2002 Tasker RA, Bernard PB, Doucette TA, Kerr DS, Zabidin Y, Alvarez-Fernandez L, Fernandez-Maroto B, Fernandez-Sanchez MT, Novelli A. Comparison of the in vitro and in vivo neurotoxicity of three new sources of kainic acid. Amino Acids. 23: 45-54. PMID 12373517 DOI: 10.1007/s00726-001-0108-4  1
2002 Duka T, Seiss E, Tasker R. The effects of extrinsic context on nicotine discrimination. Behavioural Pharmacology. 13: 39-47. PMID 11990718  1
2002 Novelli A, Tasker RA. Excitotoxicity - Introduction Amino Acids. 23: 9-10. DOI: 10.1007/s007260200028  1
2000 Doucette TA, Ryan CL, Tasker RA. Use of osmotic minipumps for sustained drug delivery in rat pups: effects on physical and neurobehavioural development. Physiology & Behavior. 71: 207-12. PMID 11134704 DOI: 10.1016/S0031-9384(00)00315-2  1
2000 Doucette TA, Strain SM, Allen GV, Ryan CL, Tasker RA. Comparative behavioural toxicity of domoic acid and kainic acid in neonatal rats. Neurotoxicology and Teratology. 22: 863-9. PMID 11120392 DOI: 10.1016/S0892-0362(00)00110-0  1
2000 Novelli A, Tasker RA. On excitotoxicity. Amino Acids. 19: 227-8. PMID 11026493  0.44
2000 Duka T, Tasker R, McGowan JF. The effects of 3-week estrogen hormone replacement on cognition in elderly healthy females. Psychopharmacology. 149: 129-39. PMID 10805607  1
1998 Duka T, Tasker R, Stephens DN. Alcohol choice and outcome expectancies in social drinkers. Behavioural Pharmacology. 9: 643-53. PMID 9862089  1
1998 Duka T, Tasker R, Russell K, Stephens DN. Discriminative stimulus properties of nicotine at low doses: the effects of caffeine preload. Behavioural Pharmacology. 9: 219-29. PMID 9832936  1
1998 Tasker RA, Strain SM. Synergism between NMDA and domoic acid in a murine model of behavioural neurotoxicity. Neurotoxicology. 19: 593-7. PMID 9745916  1
1998 Tasker RA, Connell BJ, Ross SJ, Elson CM. Development of an injectable sustained-release formulation of morphine: antinociceptive properties in rats. Laboratory Animals. 32: 270-5. PMID 9718474  1
1998 Duka T, Stephens DN, Russell C, Tasker R. Discriminative stimulus properties of low doses of ethanol in humans. Psychopharmacology. 136: 379-89. PMID 9600584 DOI: 10.1007/s002130050581  1
1997 Tasker RA, Ross SJ, Dohoo SE, Elson CM. Pharmacokinetics of an injectable sustained-release formulation of morphine for use in dogs. Journal of Veterinary Pharmacology and Therapeutics. 20: 362-7. PMID 9350256  1
1997 Dohoo SE, Tasker RA. Pharmacokinetics of oral morphine sulfate in dogs: a comparison of sustained release and conventional formulations. Canadian Journal of Veterinary Research = Revue Canadienne De Recherche VéTéRinaire. 61: 251-5. PMID 9342447  1
1996 Tasker RA, Strain SM, Drejer J. Selective reduction in domoic acid toxicity in vivo by a novel non-N-methyl-D-aspartate receptor antagonist. Canadian Journal of Physiology and Pharmacology. 74: 1047-54. PMID 8960397 DOI: 10.1139/cjpp-74-9-1047  1
1994 Connell BJ, Barnes JC, Blatt T, Tasker RA. Rapid development of tolerance to morphine in the formalin test. Neuroreport. 5: 817-20. PMID 8018856  1
1994 Dohoo S, Tasker RA, Donald A. Pharmacokinetics of parenteral and oral sustained-release morphine sulphate in dogs. Journal of Veterinary Pharmacology and Therapeutics. 17: 426-33. PMID 7707487  1
1992 Tasker RA, Connell BJ, Yole MJ. Systemic injections of alpha-1 adrenergic agonists produce antinociception in the formalin test. Pain. 49: 383-91. PMID 1357619 DOI: 10.1016/0304-3959(92)90246-8  1
1991 Tasker RA, Connell BJ, Strain SM. Pharmacology of systemically administered domoic acid in mice. Canadian Journal of Physiology and Pharmacology. 69: 378-82. PMID 2059903  1
1991 Strain SM, Tasker RA. Hippocampal damage produced by systemic injections of domoic acid in mice. Neuroscience. 44: 343-52. PMID 1944890 DOI: 10.1016/0306-4522(91)90059-W  1
1990 Blanchard JR, Tasker RA. High-performance liquid chromatographic assay for domoic acid in serum of different species. Journal of Chromatography. 526: 546-9. PMID 2361994 DOI: 10.1016/S0378-4347(00)82538-4  1
1990 Franklin KB, Abbott FV, English MJ, Jeans ME, Tasker RA, Young SN. Tryptophan-morphine interactions and postoperative pain. Pharmacology, Biochemistry, and Behavior. 35: 157-63. PMID 2315355 DOI: 10.1016/0091-3057(90)90221-3  1
1990 Tasker RAR, Connell BJ, Strain SM. Pharmacological, behavioural and morphological studies of domoic acid toxicity in vivo European Journal of Pharmacology. 183: 959. DOI: 10.1016/0014-2999(90)92800-X  1
1989 Vaccarino AL, Tasker RA, Melzack R. Analgesia produced by normal doses of opioid antagonists alone and in combination with morphine. Pain. 36: 103-9. PMID 2537485 DOI: 10.1016/0304-3959(89)90117-6  1
1989 Tasker RA, Melzack R. Different alpha-receptor subtypes are involved in clonidine-produced analgesia in different pain tests. Life Sciences. 44: 9-17. PMID 2536453 DOI: 10.1016/0024-3205(89)90212-9  1
1988 Vaccarino AL, Tasker RA, Melzack R. Systemic administration of naloxone produces analgesia in BALB/c mice in the formalin pain test. Neuroscience Letters. 84: 103-7. PMID 3347367 DOI: 10.1016/0304-3940(88)90345-X  1
1987 Tasker RA, Choinière M, Libman SM, Melzack R. Analgesia produced by injection of lidocaine into the lateral hypothalamus. Pain. 31: 237-48. PMID 3431882 DOI: 10.1016/0304-3959(87)90039-X  1
1986 Tasker RA, Nakatsu K. Metabolism and disposition of 3,6-dibutanoylmorphine in rat brain. Canadian Journal of Physiology and Pharmacology. 64: 1160-3. PMID 3779514  1
1986 Tasker RA, Nakatsu K. Simultaneous quantitation of morphine, monobutanoylmorphine and dibutanoylmorphine using short capillary column gas chromatography-mass spectrometry. The Analyst. 111: 563-5. PMID 3740426 DOI: 10.1039/AN9861100563  1
1984 Tasker RA, Nakatsu K. Evaluation of 3,6-dibutanoylmorphine as an analgesic in vivo: comparison with morphine and 3,6-diacetylmorphine. Life Sciences. 34: 1659-67. PMID 6727542 DOI: 10.1016/0024-3205(84)90637-4  1
1984 Owen JA, Tasker RA, Nakatsu K. A simple, less stressful rat restrainer. Experientia. 40: 306-8. PMID 6698193 DOI: 10.1007/BF01947596  1
1984 Tasker RA, Vander Velden PL, Nakatsu K. Relative cataleptic potency of narcotic analgesics, including 3,6-dibutanoylmorphine and 6-monoacetylmorphine. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 8: 747-50. PMID 6543399 DOI: 10.1016/0278-5846(84)90051-4  1
1983 Nakatsu K, Tasker RA, Bukowskyj M. Shortening of liquid chromatography columns for reduced retention time. Analytical Chemistry. 55: 1455-6. PMID 6614498  1
1982 Tasker RA, Nakatsu K. Rapid, reliable and sensitive assay for warfarin using normal-phase high-performance liquid chromatography. Journal of Chromatography. 228: 346-9. PMID 7076759 DOI: 10.1016/S0378-4347(00)80452-1  1
1982 Tasker RA, Nakatsu K. Factors affecting ultrafiltration-assessed values for drug binding. Clinical Chemistry. 28: 1244-6. PMID 7074924  1
1980 Tasker RAR, Nakatsu K, Brien JF, Munt P. Inter-technique variability in the determination of theophylline binding in human serum Clinical Research. 28: 667A.  1
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