Year |
Citation |
Score |
2023 |
Armour EM, Thomas CM, Greco G, Bhatnagar A, Elefant F. Experience-dependent Tip60 nucleocytoplasmic transport is regulated by its NLS/NES sequences for neuroplasticity gene control. Molecular and Cellular Neurosciences. 103888. PMID 37598897 DOI: 10.1016/j.mcn.2023.103888 |
0.497 |
|
2023 |
Bhatnagar A, Krick K, Karisetty BC, Armour EM, Heller EA, Elefant F. Tip60's novel RNA-binding function modulates alternative splicing of pre-mRNA targets implicated in Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36849418 DOI: 10.1523/JNEUROSCI.2331-22.2023 |
0.564 |
|
2021 |
Beaver M, Karisetty BC, Zhang H, Bhatnagar A, Armour E, Parmar V, Brown R, Xiang M, Elefant F. Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain. Epigenetics. 1-22. PMID 34369292 DOI: 10.1080/15592294.2021.1959742 |
0.477 |
|
2020 |
Karisetty BC, Bhatnagar A, Armour EM, Beaver M, Zhang H, Elefant F. Amyloid-β Peptide Impact on Synaptic Function and Neuroepigenetic Gene Control Reveal New Therapeutic Strategies for Alzheimer's Disease. Frontiers in Molecular Neuroscience. 13: 577622. PMID 33304239 DOI: 10.3389/fnmol.2020.577622 |
0.333 |
|
2020 |
Zhang H, Karisetty BC, Bhatnagar A, Armour EM, Beaver M, Roach TV, Mortazavi S, Mandloi S, Elefant F. Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration. Molecular and Cellular Neurosciences. 109: 103570. PMID 33160016 DOI: 10.1016/j.mcn.2020.103570 |
0.327 |
|
2020 |
Beaver M, Bhatnagar A, Panikker P, Zhang H, Snook R, Parmar V, Vijayakumar G, Betini N, Akhter S, Elefant F. Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases. Scientific Reports. 10: 18265. PMID 33106538 DOI: 10.1038/s41598-020-75035-3 |
0.488 |
|
2019 |
Li YC, Panikker P, Xing B, Yang SS, Alexandropoulos C, McEachern EP, Akumuo R, Zhao E, Gulchina Y, Pletnikov MV, Urs NM, Caron MG, Elefant F, Gao WJ. Deletion of Glycogen Synthase Kinase-3β in D Receptor-Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor-Dependent Synaptic Plasticity. Biological Psychiatry. PMID 31892408 DOI: 10.1016/J.Biopsych.2019.10.025 |
0.326 |
|
2019 |
Karnay A, Karisetty BC, Beaver M, Elefant F. Hippocampal stimulation promotes intracellular Tip60 dynamics with concomitant genome reorganization and synaptic gene activation. Molecular and Cellular Neurosciences. 101: 103412. PMID 31682915 DOI: 10.1016/J.Mcn.2019.103412 |
0.497 |
|
2019 |
Zhang H, Jia M, Wang XW, Ye C, Li Y, Wang N, Elefant F, Ma H, Cui C. Dentate gyrus μ-opioid receptor-mediated neurogenic processes are associated with alterations in morphine self-administration. Scientific Reports. 9: 1471. PMID 30728362 DOI: 10.1038/S41598-018-37083-8 |
0.337 |
|
2018 |
Panikker P, Xu SJ, Zhang H, Sarthi J, Beaver M, Sheth A, Akhter S, Elefant F. Restoring Tip60 HAT/HDAC2 balance in the neurodegenerative brain relieves epigenetic transcriptional repression and reinstates cognition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29654189 DOI: 10.1523/Jneurosci.2840-17.2018 |
0.793 |
|
2017 |
Gulchina Y, Xu SJ, Snyder MA, Elefant F, Gao WJ. Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia. Journal of Neurochemistry. PMID 28628228 DOI: 10.1111/Jnc.14101 |
0.793 |
|
2016 |
Xu S, Panikker P, Iqbal S, Elefant F. Tip60 HAT Action Mediates Environmental Enrichment Induced Cognitive Restoration. Plos One. 11: e0159623. PMID 27454757 DOI: 10.1371/Journal.Pone.0159623 |
0.821 |
|
2015 |
Xu S, Elefant F. Tip off the HAT- Epigenetic control of learning and memory by Drosophila Tip60. Fly. 9: 22-8. PMID 26327426 DOI: 10.1080/19336934.2015.1080887 |
0.834 |
|
2014 |
Xu S, Wilf R, Menon T, Panikker P, Sarthi J, Elefant F. Epigenetic control of learning and memory in Drosophila by Tip60 HAT action. Genetics. 198: 1571-86. PMID 25326235 DOI: 10.1534/Genetics.114.171660 |
0.8 |
|
2013 |
Johnson AA, Sarthi J, Pirooznia SK, Reube W, Elefant F. Increasing Tip60 HAT levels rescues axonal transport defects and associated behavioral phenotypes in a Drosophila Alzheimer's disease model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7535-47. PMID 23616558 DOI: 10.1523/Jneurosci.3739-12.2013 |
0.778 |
|
2013 |
Pirooznia SK, Elefant F. A HAT for sleep?: epigenetic regulation of sleep by Tip60 in Drosophila. Fly. 7: 99-104. PMID 23572111 DOI: 10.4161/Fly.24141 |
0.788 |
|
2013 |
Pirooznia SK, Elefant F. Targeting specific HATs for neurodegenerative disease treatment: translating basic biology to therapeutic possibilities. Frontiers in Cellular Neuroscience. 7: 30. PMID 23543406 DOI: 10.3389/Fncel.2013.00030 |
0.827 |
|
2012 |
Pirooznia SK, Chiu K, Chan MT, Zimmerman JE, Elefant F. Epigenetic regulation of axonal growth of Drosophila pacemaker cells by histone acetyltransferase tip60 controls sleep. Genetics. 192: 1327-45. PMID 22982579 DOI: 10.1534/Genetics.112.144667 |
0.819 |
|
2012 |
Pirooznia SK, Sarthi J, Johnson AA, Toth MS, Chiu K, Koduri S, Elefant F. Tip60 HAT activity mediates APP induced lethality and apoptotic cell death in the CNS of a Drosophila Alzheimer's disease model. Plos One. 7: e41776. PMID 22848598 DOI: 10.1371/Journal.Pone.0041776 |
0.796 |
|
2011 |
Sarthi J, Elefant F. dTip60 HAT activity controls synaptic bouton expansion at the Drosophila neuromuscular junction. Plos One. 6: e26202. PMID 22046262 DOI: 10.1371/Journal.Pone.0026202 |
0.804 |
|
2011 |
Lorbeck M, Pirooznia K, Sarthi J, Zhu X, Elefant F. Microarray analysis uncovers a role for Tip60 in nervous system function and general metabolism. Plos One. 6: e18412. PMID 21494552 DOI: 10.1371/Journal.Pone.0018412 |
0.737 |
|
2010 |
Singh N, Lorbeck MT, Zervos A, Zimmerman J, Elefant F. The histone acetyltransferase Elp3 plays in active role in the control of synaptic bouton expansion and sleep in Drosophila. Journal of Neurochemistry. 115: 493-504. PMID 20626565 DOI: 10.1111/J.1471-4159.2010.06892.X |
0.788 |
|
2010 |
Lorbeck MT, Singh N, Zervos A, Dhatta M, Lapchenko M, Yang C, Elefant F. The histone demethylase Dmel\Kdm4A controls genes required for life span and male-specific sex determination in Drosophila. Gene. 450: 8-17. PMID 19786080 DOI: 10.1016/J.Gene.2009.09.007 |
0.774 |
|
2007 |
Zhu X, Singh N, Donnelly C, Boimel P, Elefant F. The cloning and characterization of the histone acetyltransferase human homolog Dmel\TIP60 in Drosophila melanogaster: Dmel\TIP60 is essential for multicellular development. Genetics. 175: 1229-40. PMID 17179074 DOI: 10.1534/Genetics.106.063685 |
0.793 |
|
2006 |
Ho Y, Elefant F, Liebhaber SA, Cooke NE. Locus control region transcription plays an active role in long-range gene activation. Molecular Cell. 23: 365-75. PMID 16885026 DOI: 10.1016/J.Molcel.2006.05.041 |
0.433 |
|
2002 |
Ho Y, Elefant F, Cooke N, Liebhaber S. A defined locus control region determinant links chromatin domain acetylation with long-range gene activation. Molecular Cell. 9: 291-302. PMID 11864603 DOI: 10.1016/S1097-2765(02)00447-1 |
0.452 |
|
2000 |
Elefant F, Su Y, Liebhaber SA, Cooke NE. Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region. The Embo Journal. 19: 6814-22. PMID 11118216 DOI: 10.1093/Emboj/19.24.6814 |
0.449 |
|
2000 |
Elefant F, Cooke NE, Liebhaber SA. Targeted recruitment of histone acetyltransferase activity to a locus control region. The Journal of Biological Chemistry. 275: 13827-34. PMID 10788505 DOI: 10.1074/Jbc.275.18.13827 |
0.492 |
|
1999 |
Elefant F, Palter KB. Tissue-specific expression of dominant negative mutant Drosophila HSC70 causes developmental defects and lethality. Molecular Biology of the Cell. 10: 2101-17. PMID 10397752 DOI: 10.1091/Mbc.10.7.2101 |
0.742 |
|
1997 |
Manseau L, Baradaran A, Brower D, Budhu A, Elefant F, Phan H, Philp AV, Yang M, Glover D, Kaiser K, Palter K, Selleck S. GAL4 enhancer traps expressed in the embryo, larval brain, imaginal discs, and ovary of Drosophila. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 209: 310-22. PMID 9215645 DOI: 10.1002/(Sici)1097-0177(199707)209:3<310::Aid-Aja6>3.0.Co;2-L |
0.731 |
|
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