Tomas Björklund - Publications

Affiliations: 
Brain Repair and Imaging in Neural Systems Lund University, Lund, Skåne län, Sweden 
Area:
Parkinson's Disease, Gene therapy
Website:
http://tomas.wnc.se

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Avallone M, Pardo J, Mergiya TF, Rájová J, Räsänen A, Davidsson M, Åkerblom M, Quintino L, Kumar D, Bramham CR, Björklund T. Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated gene labeling. Frontiers in Molecular Neuroscience. 16: 1140785. PMID 37415832 DOI: 10.3389/fnmol.2023.1140785  0.653
2023 Rájová J, Davidsson M, Avallone M, Hartnor M, Aldrin-Kirk P, Cardoso T, Nolbrant S, Mollbrink A, Storm P, Heuer A, Parmar M, Björklund T. Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants . Molecular Therapy. Methods & Clinical Development. 29: 381-394. PMID 37251982 DOI: 10.1016/j.omtm.2023.04.008  0.755
2021 Aldrin-Kirk P, Åkerblom M, Cardoso T, Nolbrant S, Adler AF, Liu X, Heuer A, Davidsson M, Parmar M, Björklund T. A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants. Stem Cell Reports. PMID 34971563 DOI: 10.1016/j.stemcr.2021.11.014  0.765
2021 Björklund T, Davidsson M. Next-Generation Gene Therapy for Parkinson's Disease Using Engineered Viral Vectors. Journal of Parkinson's Disease. PMID 34366370 DOI: 10.3233/JPD-212674  0.649
2021 Parmar M, Björklund A, Björklund T. In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy? Current Opinion in Genetics & Development. 70: 76-82. PMID 34175529 DOI: 10.1016/j.gde.2021.06.002  0.348
2020 Negrini M, Wang G, Heuer A, Björklund T, Davidsson M. AAV Production Everywhere: A Simple, Fast, and Reliable Protocol for In-house AAV Vector Production Based on Chloroform Extraction. Current Protocols in Neuroscience. 93: e103. PMID 32865885 DOI: 10.1002/Cpns.103  0.638
2019 Davidsson M, Wang G, Aldrin-Kirk P, Cardoso T, Nolbrant S, Hartnor M, Mudannayake J, Parmar M, Björklund T. A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism. Proceedings of the National Academy of Sciences of the United States of America. PMID 31818949 DOI: 10.1073/Pnas.1910061116  0.768
2019 Aldrin-Kirk P, Björklund T. Practical Considerations for the Use of DREADD and Other Chemogenetic Receptors to Regulate Neuronal Activity in the Mammalian Brain. Methods in Molecular Biology (Clifton, N.J.). 1937: 59-87. PMID 30706390 DOI: 10.1007/978-1-4939-9065-8_4  0.724
2018 Tordo J, O'Leary C, Antunes ASLM, Palomar N, Aldrin-Kirk P, Basche M, Bennett A, D'Souza Z, Gleitz H, Godwin A, Holley RJ, Parker H, Liao AY, Rouse P, Youshani AS, et al. A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency. Brain : a Journal of Neurology. PMID 29788236 DOI: 10.1093/Brain/Awy126  0.743
2018 Davidsson M, Díaz-Fernández P, Torroba M, Schwich OD, Aldrin-Kirk P, Quintino L, Heuer A, Wang G, Lundberg C, Bjorklund T. Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing. Rna (New York, N.Y.). PMID 29386333 DOI: 10.1261/Rna.063925.117  0.767
2017 Aldrin-Kirk P, Heuer A, Ottosson DR, Davidsson M, Mattsson B, Björklund T. Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum. Neurobiology of Disease. PMID 29037828 DOI: 10.1016/J.Nbd.2017.10.010  0.74
2016 Davidsson M, Diaz-Fernandez P, Schwich OD, Torroba M, Wang G, Björklund T. A novel process of viral vector barcoding and library preparation enables high-diversity library generation and recombination-free paired-end sequencing. Scientific Reports. 6: 37563. PMID 27874090 DOI: 10.1038/Srep37563  0.662
2016 Aldrin-Kirk P, Heuer A, Wang G, Mattsson B, Lundblad M, Parmar M, Björklund T. DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor. Neuron. PMID 27161524 DOI: 10.1016/J.Neuron.2016.04.017  0.752
2016 Björklund T. Expression of Multiple Functional RNAs or Proteins from One Viral Vector. Methods in Molecular Biology (Clifton, N.J.). 1382: 41-56. PMID 26611577 DOI: 10.1007/978-1-4939-3271-9_3  0.312
2016 Davidsson M, Wang G, Aldrin-Kirk P, Hartnor M, Björklund T. 542. Novel Barcode-Based In Vivo Screening Method for Generating De Novo AAV Serotypes for CNS-Directed Gene Therapy Molecular Therapy. 24: S216-S217. DOI: 10.1016/S1525-0016(16)33350-0  0.768
2015 Davidsson M, Aldrin-Kirk P, Díaz-Fernández P, Quintino L, Lundberg C, Björklund T. 345. A Novel Toolbox for RNA-Editing Based on Massively Parallel Screening Using Barcoded Viral Vectors Molecular Therapy. 23: S137-S138. DOI: 10.1016/S1525-0016(16)33954-5  0.749
2015 Aldrin-Kirk P, Heuer A, Mattsson B, Wang G, Lundblad M, Parmar M, Björklund T. 18. Novel Approach Using Fetal Dopaminergic Grafts In Situ Transduced with AAV-DREADDs Significantly Increases Behavioral Motor Recovery in a Rat Model of Parkinson's Disease Molecular Therapy. 23: S8-S9. DOI: 10.1016/S1525-0016(16)33622-X  0.778
2014 Holmqvist S, Chutna O, Bousset L, Aldrin-Kirk P, Li W, Björklund T, Wang ZY, Roybon L, Melki R, Li JY. Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats. Acta Neuropathologica. 128: 805-20. PMID 25296989 DOI: 10.1007/S00401-014-1343-6  0.729
2010 Dodiya HB, Bjorklund T, Stansell J, Mandel RJ, Kirik D, Kordower JH. Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 579-87. PMID 19773746 DOI: 10.1038/Mt.2009.216  0.59
2010 Soylu R, Hult S, Björklund T, Belgardt BF, Mauer J, Brüning JC, Kirik D, Petersén Å. A24 Hypothalamic expression of mutant huntingtin causes metabolic disturbances in mice Journal of Neurology, Neurosurgery & Psychiatry. 81: A8.1-A8. DOI: 10.1136/Jnnp.2010.222570.24  0.667
2009 Björklund A, Björklund T, Kirik D. Gene therapy for dopamine replacement in Parkinson's disease. Science Translational Medicine. 1: 2ps2. PMID 20368161 DOI: 10.1126/Scitranslmed.3000350  0.558
2008 Ulusoy A, Bjorklund T, Hermening S, Kirik D. In vivo gene delivery for development of mammalian models for Parkinson's disease. Experimental Neurology. 209: 89-100. PMID 18028909 DOI: 10.1016/J.Expneurol.2007.09.011  0.573
2008 Björklund T, Morizane A, Kirik D, Brundin P. Future Cell-and Gene-Based Therapies for Parkinson's Disease Therapeutics of Parkinson's Disease and Other Movement Disorders. 145-156. DOI: 10.1002/9780470713990.ch8  0.522
2007 Eslamboli A, Romero-Ramos M, Burger C, Bjorklund T, Muzyczka N, Mandel RJ, Baker H, Ridley RM, Kirik D. Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain. Brain : a Journal of Neurology. 130: 799-815. PMID 17303591 DOI: 10.1093/Brain/Awl382  0.498
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