Year |
Citation |
Score |
2024 |
Srivastava S, Miranda P, Giraldez T, Zhu J, Cachau RE, Holmgren M. Structural bases for blockade and activation of BK channels by Ba ions. Frontiers in Molecular Biosciences. 11: 1454273. PMID 39359662 DOI: 10.3389/fmolb.2024.1454273 |
0.762 |
|
2023 |
Kshatri A, Rivero-Pérez B, Giraldez T. Subunit-specific inhibition of BK channels by piperine. Biophysical Journal. PMID 37700524 DOI: 10.1016/j.bpj.2023.09.002 |
0.461 |
|
2022 |
Mercado E, Paniagua N, Sánchez-Robles EM, Girón R, Alvarez de la Rosa D, Giraldez T, Goicoechea C. SGK1.1 isoform is involved in nociceptive modulation, offering a protective effect against noxious cold stimulus in a sexually dimorphic manner. Pharmacology, Biochemistry, and Behavior. 212: 173302. PMID 34838531 DOI: 10.1016/j.pbb.2021.173302 |
0.765 |
|
2021 |
Martin-Batista E, Manville RW, Rivero-Pérez B, Bartolomé-Martín D, Alvarez de la Rosa D, Abbott GW, Giraldez T. Activation of SGK1.1 Upregulates the M-current in the Presence of Epilepsy Mutations. Frontiers in Molecular Neuroscience. 14: 798261. PMID 34899186 DOI: 10.3389/fnmol.2021.798261 |
0.802 |
|
2021 |
Gómez R, Maglio LE, Gonzalez-Hernandez AJ, Rivero-Pérez B, Bartolomé-Martín D, Giraldez T. NMDA receptor-BK channel coupling regulates synaptic plasticity in the barrel cortex. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34453004 DOI: 10.1073/pnas.2107026118 |
0.807 |
|
2021 |
Martin-Batista E, Maglio LE, Armas-Capote N, Hernández G, Alvarez de la Rosa D, Giraldez T. SGK1.1 limits brain damage after status epilepticus through M current-dependent and independent mechanisms. Neurobiology of Disease. 153: 105317. PMID 33639207 DOI: 10.1016/j.nbd.2021.105317 |
0.782 |
|
2020 |
Cazaña-Pérez V, Cidad P, Navarro-González JF, Rojo-Mencía J, Jaisser F, López-López JR, Alvarez de la Rosa D, Giraldez T, Pérez-García MT. Kv1.3 Channel Inhibition Limits Uremia-Induced Calcification in Mouse and Human Vascular Smooth Muscle. Function (Oxford, England). 2: zqaa036. PMID 35330975 DOI: 10.1093/function/zqaa036 |
0.81 |
|
2020 |
Kshatri A, Cerrada A, Gimeno R, Bartolomé-Martín D, Rojas P, Giraldez T. Correction: Differential regulation of BK channels by fragile X mental retardation protein. The Journal of General Physiology. 152. PMID 32442240 DOI: 10.1085/Jgp.20191250205042020C |
0.41 |
|
2020 |
Kshatri A, Cerrada A, Gimeno R, Bartolomé-Martín D, Rojas P, Giraldez T. Differential regulation of BK channels by fragile X mental retardation protein. The Journal of General Physiology. 152. PMID 32275741 DOI: 10.1085/Jgp.201912502 |
0.539 |
|
2020 |
Srivastava S, Miranda P, Giráldez T, Holmgren M. Labeling and Purification of BK Channel for Single Molecule Experiments Biophysical Journal. 118: 271a-272a. DOI: 10.1016/J.Bpj.2019.11.1563 |
0.752 |
|
2020 |
Kshatri AS, Giraldez T. Reversible Block of BK Channels by Piperine Biophysical Journal. 118: 264a. DOI: 10.1016/J.Bpj.2019.11.1530 |
0.506 |
|
2020 |
Gonzalez Hernandez AJ, Rivero-Perez B, Bartolome-Martin D, de la Rosa DA, Plested AJ, Giráldez T. State-dependent Photocrosslinking at the BK Channel Intersubunit Interface Biophysical Journal. 118: 169a. DOI: 10.1016/J.Bpj.2019.11.1034 |
0.456 |
|
2019 |
Armas-Capote N, Maglio LE, Pérez-Atencio L, Martin-Batista E, Reboreda A, Barios JA, Hernandez G, Alvarez de la Rosa D, Lamas JA, Barrio LC, Giraldez T. SGK1.1 Reduces Kainic Acid-Induced Seizure Severity and Leads to Rapid Termination of Seizures. Cerebral Cortex (New York, N.Y. : 1991). PMID 31819941 DOI: 10.1093/Cercor/Bhz302 |
0.771 |
|
2019 |
Gómez R, Maglio LE, Gonzalez-Hernandez AJ, Rivero-Perez B, Giraldez T. Role of NMDAR-BK Complexes in the Integration of Synaptic Inputs of Barrel Cortex Pyramidal Neurons Biophysical Journal. 116: 36a. DOI: 10.1016/J.Bpj.2018.11.240 |
0.757 |
|
2018 |
Miranda P, Holmgren M, Giraldez T. Voltage-dependent dynamics of the BK channel cytosolic gating ring are coupled to the membrane-embedded voltage sensor. Elife. 7. PMID 30526860 DOI: 10.7554/Elife.40664 |
0.778 |
|
2018 |
Kshatri AS, Gonzalez-Hernandez A, Giraldez T. Physiological Roles and Therapeutic Potential of Ca Activated Potassium Channels in the Nervous System. Frontiers in Molecular Neuroscience. 11: 258. PMID 30104956 DOI: 10.3389/Fnmol.2018.00258 |
0.829 |
|
2018 |
Cazaña-Pérez V, Cidad P, Donate-Correa J, Martín-Núñez E, López-López JR, Pérez-García MT, Giraldez T, Navarro-González JF, Alvarez de la Rosa D. Phenotypic Modulation of Cultured Primary Human Aortic Vascular Smooth Muscle Cells by Uremic Serum. Frontiers in Physiology. 9: 89. PMID 29483881 DOI: 10.3389/Fphys.2018.00089 |
0.741 |
|
2018 |
Miranda P, Holmgren M, Giraldez T. Author response: Voltage-dependent dynamics of the BK channel cytosolic gating ring are coupled to the membrane-embedded voltage sensor Elife. DOI: 10.7554/Elife.40664.014 |
0.756 |
|
2018 |
Cerrada A, Kshatri A, Gimeno R, Giráldez T. Quantitative Analysis of Subcellular Nanodomains Formed by BK and Voltage-Gated Calcium Channels Biophysical Journal. 114: 479a-480a. DOI: 10.1016/J.Bpj.2017.11.2636 |
0.479 |
|
2018 |
Gonzalez-Hernandez AJ, Kshatri A, Giraldez T. Role of an Intrasubunit Ca2+ Bridge Dependent Activation of BK Channels Biophysical Journal. 114: 479a. DOI: 10.1016/J.Bpj.2017.11.2634 |
0.809 |
|
2018 |
Giraldez T. Molecular Rearrangements Underlying Function of Large Conductance Calcium- and Voltage-Regulated Potassium Channels Biophysical Journal. 114: 34a. DOI: 10.1016/J.Bpj.2017.11.246 |
0.471 |
|
2017 |
Kshatri AS, Gonzalez-Hernandez AJ, Giraldez T. Functional validation of Ca(2+)-binding residues from the crystal structure of the BK ion channel. Biochimica Et Biophysica Acta. PMID 28966112 DOI: 10.1016/J.Bbamem.2017.09.023 |
0.806 |
|
2017 |
Arce-Franco M, Dominguez-Luis M, Pec MK, Martínez-Gimeno C, Miranda P, Alvarez de la Rosa D, Giraldez T, García-Verdugo JM, Machado JD, Díaz-González F. Functional effects of proinflammatory factors present in Sjögren's syndrome salivary microenvironment in an in vitro model of human salivary gland. Scientific Reports. 7: 11897. PMID 28928382 DOI: 10.1038/S41598-017-12282-X |
0.764 |
|
2017 |
Giraldez T, Rothberg BS. Understanding the conformational motions of RCK gating rings. The Journal of General Physiology. PMID 28246116 DOI: 10.1085/Jgp.201611726 |
0.525 |
|
2017 |
Miranda P, Giraldez T, Holmgren M. BK Channel Gating-Ring Voltage Dependence Motions Biophysical Journal. 112: 39a. DOI: 10.1016/J.Bpj.2016.11.249 |
0.783 |
|
2016 |
Giraldez T. The GoSlo family of BK channel activators: a no-go for γ subunits? Channels (Austin, Tex.). 0. PMID 27960620 DOI: 10.1080/19336950.2016.1263136 |
0.35 |
|
2016 |
Miranda P, Giraldez T, Holmgren M. Interactions of divalent cations with calcium binding sites of BK channels reveal independent motions within the gating ring. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872281 DOI: 10.1073/Pnas.1611415113 |
0.766 |
|
2016 |
Jiménez-Canino R, Lorenzo-Díaz F, Jaisser F, Farman N, Giraldez T, Alvarez de la Rosa D. Histone deacetylase 6-controlled Hsp90 acetylation significantly alters mineralocorticoid receptor subcellular dynamics but not its transcriptional activity. Endocrinology. en20152055. PMID 27100623 DOI: 10.1210/En.2015-2055 |
0.764 |
|
2016 |
González-Montelongo R, Barros F, Alvarez de la Rosa D, Giraldez T. Plasma membrane insertion of epithelial sodium channels occurs with dual kinetics. Pflugers Archiv : European Journal of Physiology. PMID 26876388 DOI: 10.1007/S00424-016-1799-4 |
0.83 |
|
2016 |
Miranda P, Giraldez T, Holmgren M. Selective Cation Binding to the Gating-Ring Triggers Independent RCK Motions in the BK Channel Biophysical Journal. 110: 187a. DOI: 10.1016/J.Bpj.2015.11.1041 |
0.763 |
|
2015 |
Miranda P, Giraldez T, Holmgren M. Voltage Dependence of BK Channels Gating Ring Motion Studied by State Dependent FRET Biophysical Journal. 108: 119a. DOI: 10.1016/J.Bpj.2014.11.666 |
0.78 |
|
2014 |
Giraldez T. Let's twist (the S4) again. Biophysical Journal. 107: 1035-7. PMID 25185537 DOI: 10.1016/J.Bpj.2014.07.043 |
0.378 |
|
2014 |
Cabrera E, González-Montelongo R, Giraldez T, Alvarez de la Rosa D, Siverio JM. Molecular components of nitrate and nitrite efflux in yeast. Eukaryotic Cell. 13: 267-78. PMID 24363367 DOI: 10.1128/Ec.00268-13 |
0.744 |
|
2014 |
Miranda P, Giraldez T, Holmgren M. Divalent Cation-Dependent Motion of the BK Channel Gating-Ring Reported by State Dependent FRET Biophysical Journal. 106: 436a-437a. DOI: 10.1016/J.Bpj.2013.11.2459 |
0.778 |
|
2013 |
Giraldez T, DomÃnguez J, Alvarez de la Rosa D. ENaC in the brain--future perspectives and pharmacological implications. Current Molecular Pharmacology. 6: 44-9. PMID 23547934 DOI: 10.2174/1874467211306010006 |
0.829 |
|
2013 |
Alvarez de la Rosa D, Navarro-González JF, Giraldez T. ENaC modulators and renal disease. Current Molecular Pharmacology. 6: 35-43. PMID 23547933 DOI: 10.2174/1874467211306010005 |
0.814 |
|
2013 |
Miranda P, Contreras JE, Plested AJ, Sigworth FJ, Holmgren M, Giraldez T. State-dependent FRET reports calcium- and voltage-dependent gating-ring motions in BK channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 5217-22. PMID 23479636 DOI: 10.1073/Pnas.1219611110 |
0.83 |
|
2013 |
Miranda P, Cadaveira-Mosquera A, González-Montelongo R, Villarroel A, González-Hernández T, Lamas JA, Alvarez de la Rosa D, Giraldez T. The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the M-current. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2684-96. PMID 23392695 DOI: 10.1523/Jneurosci.3442-12.2013 |
0.82 |
|
2013 |
Hernández-DÃaz I, Giraldez T, Morales S, Hernandez G, Salido E, Canessa CM, Alvarez de la Rosa D. Heterogeneous nuclear ribonucleoprotein A2/B1 is a tissue-specific aldosterone target gene with prominent induction in the rat distal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G122-31. PMID 23139218 DOI: 10.1152/Ajpgi.00130.2012 |
0.774 |
|
2013 |
Miranda P, Cadaveira-Mosquera A, Gonzalez-Montelongo R, Villarroel A, Antonio Lamas J, de la Rosa DA, Giraldez T. Regulation of the Kv7.2/3 Channels by the Neuronal Serum-and Gluococorticoids-Regulated Kinase 1.1 Biophysical Journal. 104: 268a. DOI: 10.1016/J.Bpj.2012.11.1505 |
0.737 |
|
2012 |
Aivar P, Fernández-Orth J, Gomis-Perez C, Alberdi A, Alaimo A, Rodríguez MS, Giraldez T, Miranda P, Areso P, Villarroel A. Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker. Plos One. 7: e47263. PMID 23115641 DOI: 10.1371/Journal.Pone.0047263 |
0.709 |
|
2012 |
Krumm P, Giraldez T, Alvarez de la Rosa D, Clauss WG, Fronius M, Althaus M. Thiol-reactive compounds from garlic inhibit the epithelial sodium channel (ENaC). Bioorganic & Medicinal Chemistry. 20: 3979-84. PMID 22668601 DOI: 10.1016/J.Bmc.2012.05.021 |
0.783 |
|
2012 |
Aguilar-Sánchez C, Hernández-Díaz I, Lorenzo-Díaz F, Navarro JF, Hughes TE, Giraldez T, Alvarez de la Rosa D. Identification of permissive insertion sites for generating functional fluorescent mineralocorticoid receptors. Endocrinology. 153: 3517-25. PMID 22621960 DOI: 10.1210/En.2012-1210 |
0.767 |
|
2012 |
Giraldez T, Rojas P, Jou J, Flores C, Alvarez de la Rosa D. The epithelial sodium channel δ-subunit: new notes for an old song. American Journal of Physiology. Renal Physiology. 303: F328-38. PMID 22573384 DOI: 10.1152/Ajprenal.00116.2012 |
0.832 |
|
2012 |
Wesch D, Althaus M, Miranda P, Cruz-Muros I, Fronius M, González-Hernández T, Clauss WG, Alvarez de la Rosa D, Giraldez T. Differential N termini in epithelial Na+ channel δ-subunit isoforms modulate channel trafficking to the membrane. American Journal of Physiology. Cell Physiology. 302: C868-79. PMID 22159085 DOI: 10.1152/Ajpcell.00255.2011 |
0.818 |
|
2012 |
Miranda P, Contreras JE, Wesch D, Sigworth FJ, Holmgren M, Giraldez T. State-Dependent FRET Reports Large Gating-Ring Motions in BK Channels Biophysical Journal. 102: 687a. DOI: 10.1016/J.Bpj.2011.11.3735 |
0.825 |
|
2011 |
Miranda P, Contreras J, Wesch DL, Sigworth FJ, Holmgren M, Giraldez T. Calcium Induces Structural Rearrangements of the Gating Ring of the Human BK Channel Biophysical Journal. 100: 260a. DOI: 10.1016/J.Bpj.2010.12.1636 |
0.823 |
|
2010 |
Afonso-Oramas D, Cruz-Muros I, Barroso-Chinea P, Ãlvarez de la Rosa D, Castro-Hernández J, Salas-Hernández J, Giráldez T, González-Hernández T. The dopamine transporter is differentially regulated after dopaminergic lesion. Neurobiology of Disease. 40: 518-30. PMID 20688165 DOI: 10.1016/J.Nbd.2010.07.012 |
0.746 |
|
2010 |
Wesch D, Miranda P, Afonso-Oramas D, Althaus M, Castro-Hernández J, Dominguez J, Morty RE, Clauss W, González-Hernández T, Alvarez de la Rosa D, Giraldez T. The neuronal-specific SGK1.1 kinase regulates {delta}-epithelial Na+ channel independently of PY motifs and couples it to phospholipase C signaling. American Journal of Physiology. Cell Physiology. 299: C779-90. PMID 20631247 DOI: 10.1152/Ajpcell.00184.2010 |
0.824 |
|
2010 |
Hernández-DÃaz I, Giraldez T, Arnau MR, Smits VA, Jaisser F, Farman N, Alvarez de la Rosa D. The mineralocorticoid receptor is a constitutive nuclear factor in cardiomyocytes due to hyperactive nuclear localization signals. Endocrinology. 151: 3888-99. PMID 20484457 DOI: 10.1210/En.2010-0099 |
0.757 |
|
2010 |
Wesch D, Miranda P, de la Rosa DA, Giraldez T. Regulation of Delta-Enac Ion Channels by the Neuronal-Specific Sgk1.1 Kinase Biophysical Journal. 98: 96a. DOI: 10.1016/J.Bpj.2009.12.541 |
0.831 |
|
2009 |
Afonso-Oramas D, Cruz-Muros I, Alvarez de la Rosa D, Abreu P, Giráldez T, Castro-Hernández J, Salas-Hernández J, Lanciego JL, RodrÃguez M, González-Hernández T. Dopamine transporter glycosylation correlates with the vulnerability of midbrain dopaminergic cells in Parkinson's disease. Neurobiology of Disease. 36: 494-508. PMID 19766189 DOI: 10.1016/J.Nbd.2009.09.002 |
0.744 |
|
2009 |
Giraldez T. Combining Patch-clamp and Fluorescence to Study Structural Dynamics of Ion Channels Biophysical Journal. 96: 383a. DOI: 10.1016/J.Bpj.2008.12.2866 |
0.414 |
|
2009 |
Wesch D, de la Rosa DA, Giraldez T. Quantitative Analysis Of DEG/ENaC Subunits Interaction Biophysical Journal. 96: 536a. DOI: 10.1016/J.Bpj.2008.12.2767 |
0.824 |
|
2007 |
Giraldez T, Afonso-Oramas D, Cruz-Muros I, Garcia-Marin V, Pagel P, González-Hernández T, Alvarez de la Rosa D. Cloning and functional expression of a new epithelial sodium channel delta subunit isoform differentially expressed in neurons of the human and monkey telencephalon. Journal of Neurochemistry. 102: 1304-15. PMID 17472699 DOI: 10.1111/J.1471-4159.2007.04622.X |
0.816 |
|
2007 |
Pec MK, Artwohl M, Fernández JJ, Souto ML, Alvarez de la Rosa D, Giraldez T, Valenzuela-Fernández A, DÃaz-González F. Chemical modulation of VLA integrin affinity in human breast cancer cells. Experimental Cell Research. 313: 1121-34. PMID 17331499 DOI: 10.1016/j.yexcr.2007.01.015 |
0.737 |
|
2005 |
Giraldez T, Hughes TE, Sigworth FJ. Generation of functional fluorescent BK channels by random insertion of GFP variants. The Journal of General Physiology. 126: 429-38. PMID 16260837 DOI: 10.1085/Jgp.200509368 |
0.687 |
|
2005 |
Miranda P, Giráldez T, de la Peña P, Manso DG, Alonso-Ron C, Gómez-Varela D, DomÃnguez P, Barros F. Specificity of TRH receptor coupling to G-proteins for regulation of ERG K+ channels in GH3 rat anterior pituitary cells. The Journal of Physiology. 566: 717-36. PMID 15905217 DOI: 10.1113/Jphysiol.2005.085803 |
0.733 |
|
2003 |
Gomez-Varela D, Giraldez T, de la Pena P, Dupuy SG, Garcia-Manso D, Barros F. Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells. The Journal of Physiology. 547: 913-29. PMID 12562894 DOI: 10.1111/J.1469-7793.2003.00913.X |
0.784 |
|
2003 |
Gómez-Varela D, Barros F, Viloria CG, Giráldez T, Manso DG, Dupuy SG, Miranda P, de la Peña P. Relevance of the proximal domain in the amino-terminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor. Febs Letters. 535: 125-30. PMID 12560090 DOI: 10.1016/S0014-5793(02)03888-7 |
0.774 |
|
2002 |
Gómez-Varela D, de la Peña P, GarcÃa J, Giráldez T, Barros F. Influence of amino-terminal structures on kinetic transitions between several closed and open states in human erg K+ channels. The Journal of Membrane Biology. 187: 117-33. PMID 12029369 DOI: 10.1007/S00232-001-0156-4 |
0.647 |
|
2002 |
Giráldez T, de la Peña P, Gómez-Varela D, Barros F. Correlation between electrical activity and intracellular Ca2+ oscillations in GH3 rat anterior pituitary cells. Cell Calcium. 31: 65-78. PMID 11969247 DOI: 10.1054/Ceca.2001.0260 |
0.542 |
|
2000 |
Viloria CG, Barros F, Giráldez T, Gómez-Varela D, de la Peña P. Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating. Biophysical Journal. 79: 231-46. PMID 10866950 DOI: 10.1016/S0006-3495(00)76286-2 |
0.669 |
|
1998 |
Barros F, Gomez-Varela D, Viloria CG, Palomero T, Giráldez T, de la Peña P. Modulation of human erg K+ channel gating by activation of a G protein-coupled receptor and protein kinase C. The Journal of Physiology. 511: 333-46. PMID 9706014 DOI: 10.1111/J.1469-7793.1998.333Bh.X |
0.684 |
|
1997 |
Barros F, del Camino D, Pardo LA, Palomero T, Giráldez T, de la Peña P. Demonstration of an inwardly rectifying K+ current component modulated by thyrotropin-releasing hormone and caffeine in GH3 rat anterior pituitary cells. Pflã¼Gers Archiv : European Journal of Physiology. 435: 119-29. PMID 9359911 DOI: 10.1007/S004240050491 |
0.795 |
|
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