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Kenner C. Rice, Ph.D. - Publications

Affiliations: 
Drug Design and Synthesis Section, Chemical Biology Research Branch National Institute on Drug Abuse 
Area:
medicinal chemistry, drugs of abuse
Website:
http://irp.drugabuse.gov/Rice.html

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Year Citation  Score
2020 Kwilasz AJ, Todd LS, Duran-Malle JC, Schrama AEW, Mitten EH, Larson TA, Clements MA, Harris KM, Litwiler ST, Wang X, Van Dam AM, Maier SF, Rice KC, Watkins LR, Barrientos RM. Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone. Behavioural Brain Research. 112896. PMID 32905811 DOI: 10.1016/J.Bbr.2020.112896  0.92
2020 Makarova M, Barrientos RC, Torres OB, Matyas GR, Jacobson AE, Sulima A, Rice KC. Synthesis of a Deuterated 6-AmHap Internal Standard for the Determination of Hapten Density in a Heroin Vaccine Drug Product. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 32876947 DOI: 10.1002/Jlcr.3880  0.88
2020 Barrientos RC, Bow EW, Whalen C, Torres OB, Sulima A, Beck Z, Jacobson AE, Rice KC, Matyas GR. A novel vaccine that blunts fentanyl effects and sequesters ultrapotent fentanyl analogs. Molecular Pharmaceutics. PMID 32787282 DOI: 10.1021/Acs.Molpharmaceut.0C00497  0.88
2020 Green-Fulgham SM, Ball JB, Maier SF, Rice KC, Watkins LR, Grace PM. Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists. Journal of Neuroscience Research. PMID 32533604 DOI: 10.1002/Jnr.24645  0.92
2020 Wang M, Irvin TC, Herdman CA, Hanna RD, Hassan SA, Lee YS, Kaska S, Crowley RS, Prisinzano TE, Withey SL, Paronis CA, Bergman J, Inan S, Geller EB, Adler MW, ... ... Rice KC, et al. The Intriguing Effects of Substituents in the -Phenethyl Moiety of Norhydromorphone: A Bifunctional Opioid from a Set of "Tail Wags Dog" Experiments. Molecules (Basel, Switzerland). 25. PMID 32517185 DOI: 10.3390/Molecules25112640  0.64
2020 Dripps IJ, Chen R, Shafer AM, Livingston KE, Disney A, Husbands SM, Traynor JR, Rice KC, Jutkiewicz EM. Pharmacological Properties of Delta Opioid Receptor-Mediated Behaviors: Agonist Efficacy and Receptor Reserve. The Journal of Pharmacology and Experimental Therapeutics. PMID 32467352 DOI: 10.1124/Jpet.119.262717  0.64
2020 Robertson SA, Hutchinson MR, Rice KC, Chin PY, Moldenhauer LM, Stark MJ, Olson DM, Keelan JA. Targeting Toll-like receptor-4 to tackle preterm birth and fetal inflammatory injury. Clinical & Translational Immunology. 9: e1121. PMID 32313651 DOI: 10.1002/Cti2.1121  0.92
2020 Doyle MR, Sulima A, Rice KC, Collins GT. Interactions between reinforcement history and drug-primed reinstatement: Studies with MDPV and mixtures of MDPV and caffeine. Addiction Biology. e12904. PMID 32237282 DOI: 10.1111/Adb.12904  1
2020 Chen Y, Moutal A, Navratilova E, Kopruszinski C, Yue X, Ikegami M, Chow M, Kanazawa I, Bellampalli SS, Xie J, Patwardhan A, Rice K, Fields H, Akopian A, Neugebauer V, et al. Erratum: The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females (Science Translational Medicine DOI: 10.1126/scitranslmed.aay7550) Science Translational Medicine. 12. PMID 32132219 DOI: 10.1126/Scitranslmed.Abb4549  0.36
2020 Hyatt WS, Hirsh CE, Russell LN, Chitre NM, Murnane KS, Rice KC, Fantegrossi WE. The synthetic cathinone 3,4-methylenedioxypyrovalerone increases impulsive action in rats. Behavioural Pharmacology. PMID 32101987 DOI: 10.1097/Fbp.0000000000000548  0.92
2020 Wahid HH, Chin PY, Sharkey DJ, Diener KR, Hutchinson MR, Rice KC, Moldenhauer LM, Robertson SA. Toll-like receptor-4 antagonist (+)-naltrexone protects against carbamyl-platelet activating factor (Cpaf)-induced preterm labor in mice. The American Journal of Pathology. PMID 32084361 DOI: 10.1016/J.Ajpath.2020.01.008  0.92
2020 Chen Y, Moutal A, Navratilova E, Kopruszinski C, Yue X, Ikegami M, Chow M, Kanazawa I, Bellampalli SS, Xie J, Patwardhan A, Rice K, Fields H, Akopian A, Neugebauer V, et al. The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females. Science Translational Medicine. 12. PMID 32024801 DOI: 10.1126/Scitranslmed.Aay7550  0.36
2019 Fulenwider HD, Nennig SE, Hafeez H, Price ME, Baruffaldi F, Pravetoni M, Cheng K, Rice KC, Manvich DF, Schank JR. Sex differences in oral oxycodone self-administration and stress-primed reinstatement in rats. Addiction Biology. e12822. PMID 31830773 DOI: 10.1111/Adb.12822  0.84
2019 Schindler CW, Thorndike EB, Walters HM, Walther D, Rice KC, Baumann MH. Stereoselective neurochemical, behavioral, and cardiovascular effects of α-pyrrolidinovalerophenone enantiomers in male rats. Addiction Biology. e12842. PMID 31724254 DOI: 10.1111/Adb.12842  0.48
2019 Chin PY, Dorian C, Sharkey DJ, Hutchinson MR, Rice KC, Moldenhauer LM, Robertson SA. Toll-like receptor-4 antagonist (+)-naloxone confers sexually dimorphic protection from inflammation-induced fetal programming in mice. Endocrinology. PMID 31504393 DOI: 10.1210/En.2019-00493  0.92
2019 Nelson KH, Manke HN, Imanalieva A, Rice KC, Riley AL. Sex differences in α-pyrrolidinopentiophenone (α-PVP)-induced taste avoidance, place preference, hyperthermia and locomotor activity in rats. Pharmacology, Biochemistry, and Behavior. 172762. PMID 31445057 DOI: 10.1016/J.Pbb.2019.172762  0.84
2019 Collins GT, Sulima A, Rice KC, France CP. Self-administration of the synthetic cathinones 3,4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinopentiophenone (α-PVP) in rhesus monkeys. Psychopharmacology. PMID 31346629 DOI: 10.1007/S00213-019-05339-4  1
2019 Oppong-Damoah A, Curry KE, Blough BE, Rice KC, Murnane KS. Effects of the synthetic psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI) on ethanol consumption and place conditioning in male mice. Psychopharmacology. PMID 31309240 DOI: 10.1007/S00213-019-05328-7  0.92
2019 Wang X, Northcutt AL, Cochran TA, Zhang X, Fabisiak TJ, Haas ME, Amat J, Li H, Rice KC, Maier S, Bachtell RK, Hutchinson MR, Watkins LR. Methamphetamine activates Toll-like receptor 4 to induce central immune signaling within the ventral tegmental area and contributes to extracellular dopamine increase in the nucleus accumbens shell. Acs Chemical Neuroscience. PMID 31282647 DOI: 10.1021/Acschemneuro.9B00225  0.92
2019 Nelson BS, Fulenwider HD, Nennig SE, Smith BM, Sequeira MK, Chimberoff SH, Richie CT, Cheng K, Rice KC, Harvey BK, Heilig M, Schank JR. Escalated Alcohol Self-Administration and Sensitivity to Yohimbine-Induced Reinstatement in Alcohol Preferring Rats: Potential Role of Neurokinin-1 Receptors in the Amygdala. Neuroscience. PMID 31242442 DOI: 10.1016/J.Neuroscience.2019.06.023  0.84
2019 Hyatt WS, Berquist MD, Chitre NM, Russell LN, Rice KC, Murnane KS, Fantegrossi WE. Repeated administration of synthetic cathinone 3,4-methylenedioxypyrovalerone persistently increases impulsive choice in rats. Behavioural Pharmacology. PMID 31211703 DOI: 10.1097/Fbp.0000000000000492  0.92
2019 Ray A, Canal CE, Ehlen JC, Rice KC, Murnane KS. M100907 and BD 1047 Attenuate the Acute Toxic Effects of Methamphetamine. Neurotoxicology. PMID 31163210 DOI: 10.1016/J.Neuro.2019.05.011  0.92
2019 Zhang X, Peng Y, Grace PM, Metcalf MD, Kwilasz AJ, Wang Y, Zhang T, Wu S, Selfridge BR, Portoghese PS, Rice KC, Watkins LR, Hutchinson MR, Wang X. Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900173RRR. PMID 31162938 DOI: 10.1096/Fj.201900173Rrr  0.92
2019 Luethi D, Kolaczynska KE, Walter M, Suzuki M, Rice KC, Blough BE, Hoener MC, Baumann MH, Liechti ME. Metabolites of the ring-substituted stimulants MDMA, methylone and MDPV differentially affect human monoaminergic systems. Journal of Psychopharmacology (Oxford, England). 269881119844185. PMID 31038382 DOI: 10.1177/0269881119844185  0.52
2019 Murnane KS, Guner OF, Bowen JP, Rambacher KM, Moniri NH, Murphy TJ, Daphney CM, Oppong-Damoah A, Rice KC. The adrenergic receptor antagonist carvedilol interacts with serotonin 2A receptors both in vitro and in vivo. Pharmacology, Biochemistry, and Behavior. PMID 30998954 DOI: 10.1016/J.Pbb.2019.04.003  0.92
2019 Curry DW, Berro LF, Belkoff AR, Sulima A, Rice KC, Howell LL. Sensitization to the prosocial effects of 3,4-methylenedioxymethamphetamine (MDMA). Neuropharmacology. PMID 30922893 DOI: 10.1016/J.Neuropharm.2019.03.017  0.88
2019 Cai NS, Quiroz C, Bonaventura J, Bonifazi A, Cole TO, Purks J, Billing AS, Massey E, Wagner M, Wish ED, Guitart X, Rea W, Lam S, Moreno E, Casadó-Anguera V, ... ... Rice KC, et al. Opioid-galanin receptor heteromers mediate the dopaminergic effects of opioids. The Journal of Clinical Investigation. 130. PMID 30913037 DOI: 10.1172/Jci126912  0.64
2019 Schindler CW, Thorndike EC, Rice KC, Partilla JS, Baumann MH. The supplement adulterant β-methylphenethylamine (BMPEA, 2-phenylpropan-1-amine) increases blood pressure by acting at peripheral norepinephrine transporters. The Journal of Pharmacology and Experimental Therapeutics. PMID 30898867 DOI: 10.1124/Jpet.118.255976  0.48
2019 Schwienteck KL, Faunce KE, Rice KC, Obeng S, Zhang Y, Blough BE, Grim TW, Stevens Negus S, Banks ML. Effectiveness comparisons of G-protein biased and unbiased mu opioid receptor ligands in warm water tail-withdrawal and drug discrimination in male and female rats. Neuropharmacology. PMID 30660628 DOI: 10.1016/J.Neuropharm.2019.01.020  0.68
2019 Cornelissen JC, Steele FF, Tenney RD, Obeng S, Rice KC, Zhang Y, Banks ML. Role of mu-opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64-6198 in rhesus monkeys. European Journal of Pharmacology. 844: 175-182. PMID 30552903 DOI: 10.1016/J.Ejphar.2018.12.021  0.68
2019 Odabas-Geldiay M, Shields H, Berro LF, Rice KC, Howell LL. Effects of acute treatments with the serotonin 2A antagonist M100907 alone or in combination with the serotonin 2C agonist WAY163909 on methamphetamine self-administration in rhesus monkeys. Drug and Alcohol Dependence. 194: 252-256. PMID 30469095 DOI: 10.1016/J.Drugalcdep.2018.10.018  0.76
2019 Kwilasz AJ, Todd LS, Duran-Malle LC, Schrama AE, Mitten EH, Dam AMV, Maier SF, Rice KC, Watkins LR, Barrientos RM. Abstract # 3170 The TLR2/4 antagonist (+)-naltrexone blocks contextual long-term memory deficits in experimental autoimmune encephalitis and associated neuroinflammation in hippocampus Brain Behavior and Immunity. 76. DOI: 10.1016/J.Bbi.2018.11.282  0.92
2018 Uhl GR, Martinez MJ, Paik P, Sulima A, Bi GH, Iyer MR, Gardner E, Rice KC, Xi ZX. Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist. Proceedings of the National Academy of Sciences of the United States of America. PMID 30348770 DOI: 10.1073/Pnas.1720446115  0.88
2018 Nelson KH, López-Arnau R, Hempel BJ, To P, Manke HN, Crissman ME, Clasen MM, Rice KC, Riley AL. Stereoselective effects of the second-generation synthetic cathinone α-pyrrolidinopentiophenone (α-PVP): assessments of conditioned taste avoidance in rats. Psychopharmacology. PMID 30334086 DOI: 10.1007/S00213-018-5070-X  0.84
2018 Gannon BM, Baumann MH, Walther D, Jimenez-Morigosa C, Sulima A, Rice KC, Collins GT. The abuse-related effects of pyrrolidine-containing cathinones are related to their potency and selectivity to inhibit the dopamine transporter. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 43: 2399-2407. PMID 30305739 DOI: 10.1038/S41386-018-0209-3  1
2018 Gannon BM, Mesmin MP, Sulima A, Rice KC, Collins GT. Behavioral economic analysis of the reinforcing effects of "bath salts" mixtures: studies with MDPV, methylone, and caffeine in male Sprague-Dawley rats. Psychopharmacology. PMID 30267131 DOI: 10.1007/S00213-018-5046-X  1
2018 Trychta KA, Heathward EJ, Sulima A, Bäck S, Farokhnia M, Richie CT, Leggio L, Rice KC, Harvey BK. Extracellular esterase activity as an indicator of endoplasmic reticulum calcium depletion. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 1-10. PMID 30095301 DOI: 10.1080/1354750X.2018.1490968  0.88
2018 Shi X, Guo TZ, Li W, Sahbaie P, Rice KC, Sulima A, Clark JD, Kingery WS. Exercise Reverses Nociceptive Sensitization, Upregulated Neuropeptide Signaling, Inflammatory Changes, Anxiety, and Memory Impairment in a Mouse Tibia Fracture Model. Anesthesiology. PMID 29994924 DOI: 10.1097/Aln.0000000000002332  0.88
2018 Anttila JE, Albert K, Wires ES, Mätlik K, Loram LC, Watkins LR, Rice KC, Wang Y, Harvey BK, Airavaara M. Post-stroke Intranasal (+)-Naloxone Delivery Reduces Microglial Activation and Improves Behavioral Recovery from Ischemic Injury. Eneuro. 5. PMID 29766045 DOI: 10.1523/ENEURO.0395-17.2018  0.92
2018 Sequeira MK, Nelson BS, Fulenwider HD, King CE, Nennig SE, Bohannon JB, Cheng K, Rice KC, Heilig M, Schank JR. The neurokinin-1 receptor mediates escalated alcohol intake induced by multiple drinking models. Neuropharmacology. 137: 194-201. PMID 29758386 DOI: 10.1016/J.Neuropharm.2018.05.005  0.84
2018 Torres OB, Duval AJ, Sulima A, Antoline JFG, Jacobson AE, Rice KC, Alving CR, Matyas GR. A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids. Analytical and Bioanalytical Chemistry. PMID 29675707 DOI: 10.1007/S00216-018-1060-4  0.88
2018 Cone K, Lanpher J, Kinens A, Richard P, Couture S, Brackin R, Payne E, Harrington K, Rice KC, Stevenson GW. Delta/mu opioid receptor interactions in operant conditioning assays of pain-depressed responding and drug-induced rate suppression: assessment of therapeutic index in male Sprague Dawley rats. Psychopharmacology. PMID 29572653 DOI: 10.1007/S00213-018-4876-X  0.4
2018 Zhang X, Cui F, Chen H, Zhang T, Yang K, Wang Y, Jiang Z, Rice KC, Watkins LR, Hutchinson MR, Li Y, Peng Y, Wang X. Dissecting the Innate Immune Recognition of Opioid Inactive Isomer (+)-Naltrexone Derived Toll-like Receptor 4 (TLR4) Antagonists. Journal of Chemical Information and Modeling. PMID 29518316 DOI: 10.1021/Acs.Jcim.7B00717  0.92
2018 Elmore JS, Decker AM, Sulima A, Rice KC, Partilla JS, Blough BE, Baumann MH. Comparative neuropharmacology of N-(2-methoxybenzyl)-2,5-dimethoxyphenethylamine (NBOMe) hallucinogens and their 2C counterparts in male rats. Neuropharmacology. PMID 29501528 DOI: 10.1016/J.Neuropharm.2018.02.033  0.88
2018 Fulenwider HD, Smith BM, Nichenko AS, Carpenter JM, Nennig SE, Cheng K, Rice KC, Schank JR. Cellular and behavioral effects of lipopolysaccharide treatment are dependent upon neurokinin-1 receptor activation. Journal of Neuroinflammation. 15: 60. PMID 29486768 DOI: 10.1186/S12974-018-1098-4  0.84
2018 Cornelissen JC, Obeng S, Rice KC, Zhang Y, Negus SS, Banks M. Application of receptor theory to the design and use of fixed-proportion mu-opioid agonist and antagonist mixtures in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. PMID 29330156 DOI: 10.1124/Jpet.117.246439  0.68
2017 Remeniuk B, King T, Suktankhar D, Nippert A, Li N, Li F, Cheng K, Rice KC, Porreca F. Disease modifying actions of IL-6 blockade in a rat model of bone cancer pain. Pain. PMID 29300279 DOI: 10.1097/J.Pain.0000000000001139  0.84
2017 Dripps IJ, Boyer BT, Neubig RR, Rice KC, Traynor JR, Jutkiewicz EM. Role of signaling molecules in behaviors mediated by the δ-receptor agonist SNC80. British Journal of Pharmacology. PMID 29278419 DOI: 10.1111/Bph.14131  0.64
2017 Torres OB, Matyas GR, Rao M, Peachman KK, Jalah R, Beck Z, Michael NL, Rice KC, Jacobson AE, Alving CR. Heroin-HIV-1 (H2) vaccine: induction of dual immunologic effects with a heroin hapten-conjugate and an HIV-1 envelope V2 peptide with liposomal lipid A as an adjuvant. Npj Vaccines. 2: 13. PMID 29263870 DOI: 10.1038/s41541-017-0013-9  0.6
2017 Sulima A, Jalah R, Antoline JFG, Torres OB, Imler GH, Deschamps JR, Beck Z, Alving CR, Jacobson AE, Rice KC, Matyas GR. A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse. Journal of Medicinal Chemistry. PMID 29236495 DOI: 10.1021/Acs.Jmedchem.7B01427  0.88
2017 Gannon BM, Sulima A, Rice KC, Collins GT. Inhibition of cocaine and 3,4-methylenedioxypyrovalerone (MDPV) self-administration by lorcaserin is mediated by 5-HT2C receptors in rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 29217539 DOI: 10.1124/Jpet.117.246082  1
2017 Clasen MM, Flax SM, Hempel BJ, Cheng K, Rice KC, Riley AL. Antagonism of the kappa opioid receptor attenuates THC-induced place aversions in adult male Sprague-Dawley rats. Pharmacology, Biochemistry, and Behavior. PMID 29100992 DOI: 10.1016/J.Pbb.2017.10.010  0.84
2017 Moerke MJ, Banks ML, Cheng K, Rice KC, Negus SS. Maintenance on naltrexone+amphetamine decreases cocaine-vs.-food choice in male rhesus monkeys. Drug and Alcohol Dependence. 181: 85-93. PMID 29040826 DOI: 10.1016/J.Drugalcdep.2017.09.020  0.84
2017 Jacobsen JH, Buisman-Pijlman F, Mustafa S, Rice KC, Hutchinson MR. Antagonising TLR4-TRIF signalling before or after a low-dose alcohol binge during adolescence prevents alcohol drinking but not seeking behaviour in adulthood. Neuropharmacology. PMID 28947376 DOI: 10.1016/J.Neuropharm.2017.09.028  0.92
2017 Gannon BM, Williamson A, Rice KC, Fantegrossi WE. Role of monoaminergic systems and ambient temperature in bath salts constituent 3,4-methylenedioxypyrovalerone (MDPV) elicited hyperthermia and locomotor stimulation in mice. Neuropharmacology. PMID 28887185 DOI: 10.1016/J.Neuropharm.2017.09.004  1
2017 Gannon BM, Russell LN, Modi MS, Rice KC, Fantegrossi WE. Effects of orally self-administered bath salt constituent 3,4-methylenedioxypyrovalerone (MDPV) in mice. Drug and Alcohol Dependence. 179: 408-415. PMID 28866386 DOI: 10.1016/J.Drugalcdep.2017.06.031  1
2017 Jacobsen JHW, Buisman-Pijlman FT, Mustafa S, Rice KC, Hutchinson MR. The efficacy of (+)-Naltrexone on alcohol preference and seeking behaviour is dependent on light-cycle. Brain, Behavior, and Immunity. PMID 28864261 DOI: 10.1016/J.Bbi.2017.08.021  0.92
2017 Grace PM, Strand KA, Galer EL, Rice KC, Maier SF, Watkins LR. Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats. Brain, Behavior, and Immunity. PMID 28860068 DOI: 10.1016/J.Bbi.2017.08.018  0.92
2017 Gannon BM, Galindo KI, Mesmin MP, Sulima A, Rice KC, Collins GT. Relative reinforcing effects of second-generation synthetic cathinones: Acquisition of self-administration and fixed ratio dose-response curves in rats. Neuropharmacology. PMID 28811192 DOI: 10.1016/J.Neuropharm.2017.08.018  1
2017 Lantz SM, Rosas-Hernandez H, Cuevas E, Robinson B, Rice KC, Fantegrossi WE, Imam SZ, Paule MG, Ali SF. Monoaminergic toxicity induced by cathinone phthalimide: an in vitro study. Neuroscience Letters. PMID 28684237 DOI: 10.1016/J.Neulet.2017.06.059  0.92
2017 Gannon BM, Galindo KI, Mesmin MP, Rice KC, Collins GT. Reinforcing Effects of Binary Mixtures of Common bath salts Constituents: Studies with 3,4-Methylenedioxypyrovalerone (MDPV), 3,4-Methylenedioxymethcathinone (Methylone), and Caffeine in Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28677665 DOI: 10.1038/Npp.2017.141  1
2017 Wires ES, Trychta KA, Bäck S, Sulima A, Rice KC, Harvey BK. High fat diet disrupts endoplasmic reticulum calcium homeostasis in the rat liver. Journal of Hepatology. PMID 28596111 DOI: 10.1016/J.Jhep.2017.05.023  0.88
2017 Gannon BM, Rice KC, Collins GT. Reinforcing effects of abused 'bath salts' constituents 3,4-methylenedioxypyrovalerone and α-pyrrolidinopentiophenone and their enantiomers. Behavioural Pharmacology. PMID 28570297 DOI: 10.1097/Fbp.0000000000000315  1
2017 Nelson KH, Hempel BJ, Clasen MM, Rice KC, Riley AL. Conditioned taste avoidance, conditioned place preference and hyperthermia induced by the second generation 'bath salt' α-pyrrolidinopentiophenone (α-PVP). Pharmacology, Biochemistry, and Behavior. PMID 28427995 DOI: 10.1016/J.Pbb.2017.04.003  0.84
2017 Pitts EG, Minerva AR, Oliver EB, Kohn JN, Logun MT, Sulima A, Rice KC, Howell LL. 3,4-Methylenedioxymethamphetamine Increases Affiliative Behaviors in Squirrel Monkeys in a Serotonin 2A Receptor-Dependent Manner. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28425496 DOI: 10.1038/Npp.2017.80  0.88
2017 Wieseler J, Ellis A, McFadden A, Stone K, Brown K, Cady S, Bastos LF, Sprunger D, Rezvani N, Johnson K, Rice KC, Maier SF, Watkins LR. Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators. Brain Research. PMID 28322750 DOI: 10.1016/J.Brainres.2017.03.011  0.92
2017 Truong PM, Hassan SA, Lee YS, Kopajtic TA, Katz JL, Chadderdon AM, Traynor JR, Deschamps JR, Jacobson AE, Rice KC. Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study. Bioorganic & Medicinal Chemistry. PMID 28314512 DOI: 10.1016/J.Bmc.2017.02.064  0.64
2017 Gannon BM, Galindo KI, Rice KC, Collins GT. Individual differences in the relative reinforcing effects of 3,4-methylenedioxypyrovalerone (MDPV) under fixed and progressive ratio schedules of reinforcement in rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 28179474 DOI: 10.1124/Jpet.116.239376  1
2016 Perez Diaz M, Andersen ML, Rice KC, Howell LL. Effects of a Serotonin 2C Agonist and a 2A Antagonist on Actigraphy-Based Sleep Parameters Disrupted by Methamphetamine Self-Administration in Rhesus Monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27986974 DOI: 10.1038/Npp.2016.280  0.76
2016 Baumann MH, Bukhari MO, Lehner KR, Anizan S, Rice KC, Concheiro M, Huestis MA. Neuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs. Current Topics in Behavioral Neurosciences. PMID 27830575 DOI: 10.1007/7854_2016_53  0.48
2016 Chin PY, Dorian CL, Hutchinson MR, Olson DM, Rice KC, Moldenhauer LM, Robertson SA. Novel Toll-like receptor-4 antagonist (+)-naloxone protects mice from inflammation-induced preterm birth. Scientific Reports. 6: 36112. PMID 27819333 DOI: 10.1038/Srep36112  0.92
2016 Schindler CW, Thorndike EB, Suzuki M, Rice KC, Baumann MH. Pharmacological Mechanisms Underlying the Cardiovascular Effects of the "Bath Salt" Constituent 3,4-Methylenedioxypyrovalerone (MDPV). British Journal of Pharmacology. PMID 27714779 DOI: 10.1111/Bph.13640  0.52
2016 Elmore J, Dillon-Carter O, Partilla J, Ellefsen KN, Concheiro M, Suzuki M, Rice KC, Huestis MA, Baumann MH. Pharmacokinetic Profiles and Pharmacodynamic Effects for Methylone and its Metabolites in Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27658484 DOI: 10.1038/Npp.2016.213  0.52
2016 Serafine KM, Rice KC, France CP. Characterization of the discriminative stimulus effects of lorcaserin in rats. Journal of the Experimental Analysis of Behavior. PMID 27640338 DOI: 10.1002/Jeab.222  0.84
2016 Dripps IJ, Wang Q, Neubig RR, Rice KC, Traynor JR, Jutkiewicz EM. The role of regulator of G protein signaling 4 in delta-opioid receptor-mediated behaviors. Psychopharmacology. PMID 27624599 DOI: 10.1007/S00213-016-4432-5  0.64
2016 Woloshchuk CJ, Nelson KH, Rice KC, Riley AL. Effects of 3,4-methylenedioxypyrovalerone (MDPV) pre-exposure on the aversive effects of MDPV, cocaine and lithium chloride: Implications for abuse vulnerability. Drug and Alcohol Dependence. PMID 27520883 DOI: 10.1016/J.Drugalcdep.2016.08.008  0.84
2016 Ellis A, Grace PM, Wieseler J, Favret J, Springer K, Skarda B, Hutchinson MR, Falci S, Rice KC, Maier SF, Watkins LR. Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury. Brain, Behavior, and Immunity. PMID 27519154 DOI: 10.1016/J.Bbi.2016.08.004  0.72
2016 Collins GT, Abbott M, Galindo K, Rush EL, Rice KC, France CP. Discriminative stimulus effects of binary drug mixtures: studies with cocaine, MDPV, and caffeine. The Journal of Pharmacology and Experimental Therapeutics. PMID 27493274 DOI: 10.1124/Jpet.116.234252  1
2016 Rosas-Hernandez H, Cuevas E, Lantz SM, Rice KC, Gannon BM, Fantegrossi WE, Gonzalez C, Paule MG, Ali SF. Methamphetamine, 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxypyrovalerone (MDPV) induce differential cytotoxic effects in bovine brain microvessel endothelial cells. Neuroscience Letters. PMID 27320055 DOI: 10.1016/J.Neulet.2016.06.029  1
2016 Grace PM, Strand KA, Galer EL, Urban DJ, Wang X, Baratta MV, Fabisiak TJ, Anderson ND, Cheng K, Greene LI, Berkelhammer D, Zhang Y, Ellis AL, Yin HH, Campeau S, ... Rice KC, et al. Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247388 DOI: 10.1073/Pnas.1602070113  0.36
2016 Katz JL, Hiranita T, Kopajtic TA, Rice KC, Mesangeau C, Narayanan S, Abdelazeem AH, McCurdy CR. Blockade of Cocaine or Sigma Receptor Agonist Self-Administration by Subtype- Selective Sigma Receptor Antagonists. The Journal of Pharmacology and Experimental Therapeutics. PMID 27189970 DOI: 10.1124/Jpet.116.232728  0.72
2016 Saccone PA, Zelenock KA, Linsdey AM, Sulima A, Rice KC, Prinssen EP, Wichmann J, Woods JH. Characterization of the discriminative stimulus effects of a NOP receptor agonist Ro 64-6198 in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. PMID 26801398 DOI: 10.1124/Jpet.115.231134  0.72
2016 Gannon BM, Williamson A, Suzuki M, Rice KC, Fantegrossi WE. Stereoselective Effects of Abused "Bath Salt" Constituent 3,4-Methylenedioxypyrovalerone in Mice: Drug Discrimination, Locomotor Activity, and Thermoregulation. The Journal of Pharmacology and Experimental Therapeutics. 356: 615-23. PMID 26769917 DOI: 10.1124/Jpet.115.229500  1
2016 Gannon BM, Williamson A, Suzuki M, Rice KC, Fantegrossi WE. Stereoselective effects of abused "bath salt" constituent 3,4-methylenedioxypyrovalerone in mice: Drug discrimination, locomotor activity, and thermoregulation Journal of Pharmacology and Experimental Therapeutics. 356: 615-623. DOI: 10.1124/jpet.115.229500  0.72
2015 Pomrenze MB, Millan EZ, Hopf FW, Keiflin R, Maiya R, Blasio A, Dadgar J, Kharazia V, De Guglielmo G, Crawford E, Janak PH, George O, Rice KC, Messing RO. A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. Frontiers in Neuroscience. 9: 487. PMID 26733798 DOI: 10.3389/Fnins.2015.00487  0.72
2015 Torres OB, Antoline JF, Li F, Jalah R, Jacobson AE, Rice KC, Alving CR, Matyas GR. A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse. Analytical and Bioanalytical Chemistry. PMID 26677020 DOI: 10.1007/S00216-015-9223-Z  0.6
2015 Wang X, Zhang Y, Peng Y, Hutchinson MR, Rice KC, Yin H, Watkins LR. Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as Toll-like receptor 4 antagonists. British Journal of Pharmacology. PMID 26603732 DOI: 10.1111/Bph.13394  0.72
2015 Zhang C, Kuo CC, Moghadam SH, Monte L, Campbell SN, Rice KC, Sawchenko PE, Masliah E, Rissman RA. Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26555315 DOI: 10.1016/J.Jalz.2015.09.007  0.72
2015 Serafine KM, Rice KC, France CP. Directly Observable Behavioral Effects of Lorcaserin in Rats. The Journal of Pharmacology and Experimental Therapeutics. 355: 381-5. PMID 26384326 DOI: 10.1124/Jpet.115.228148  0.72
2015 Ayanwuyi LO, Stopponi S, Ubaldi M, Cippitelli A, Nasuti C, Damadzic R, Heilig M, Schank J, Cheng K, Rice KC, Ciccocioppo R. Neurokinin 1 receptor blockade in the medial amygdala attenuates alcohol drinking in rats with innate anxiety but not in wistar rats. British Journal of Pharmacology. PMID 26275374 DOI: 10.1111/Bph.13280  0.72
2015 King HE, Wakeford A, Taylor W, Wetzell B, Rice KC, Riley AL. Sex differences in 3,4-methylenedioxypyrovalerone (MDPV)-induced taste avoidance and place preferences. Pharmacology, Biochemistry, and Behavior. 137: 16-22. PMID 26216834 DOI: 10.1016/J.Pbb.2015.07.013  0.72
2015 Schank JR, Nelson BS, Damadzic R, Tapocik JD, Yao M, King CE, Rowe KE, Cheng K, Rice KC, Heilig M. Neurokinin-1 receptor antagonism attenuates neuronal activity triggered by stress-induced reinstatement of alcohol seeking. Neuropharmacology. 99: 106-114. PMID 26188146 DOI: 10.1016/J.Neuropharm.2015.07.009  0.84
2015 Wahid HH, Dorian C, Yin Chin P, Hutchinson MR, Rice KC, Olson DM, Moldenhauer LM, Robertson SA. Toll-like receptor 4 is an essential upstream regulator of on-time parturition and perinatal viability in mice. Endocrinology. EN20151089. PMID 26151355 DOI: 10.1210/En.2015-1089  0.72
2015 Anastasio NC, Stutz SJ, Fink LH, Swinford-Jackson SE, Sears RM, DiLeone RJ, Rice KC, Moeller FG, Cunningham KA. Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity. Acs Chemical Neuroscience. PMID 26120876 DOI: 10.1021/Acschemneuro.5B00094  0.96
2015 Flax SM, Wakeford AG, Cheng K, Rice KC, Riley AL. Effect of norbinaltorphimine on ∆(9)-tetrahydrocannabinol (THC)-induced taste avoidance in adolescent and adult Sprague-Dawley rats. Psychopharmacology. PMID 26025420 DOI: 10.1007/S00213-015-3970-6  0.72
2015 Bachtell R, Hutchinson MR, Wang X, Rice KC, Maier SF, Watkins LR. Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4. Cns & Neurological Disorders Drug Targets. 14: 692-9. PMID 26022268 DOI: 10.2174/1871527314666150529132503  0.92
2015 Selfridge BR, Wang X, Zhang Y, Yin H, Grace PM, Watkins LR, Jacobson AE, Rice KC. Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists. Journal of Medicinal Chemistry. 58: 5038-52. PMID 26010811 DOI: 10.1021/Acs.Jmedchem.5B00426  0.96
2015 Jalah R, Torres OB, Mayorov AV, Li F, Antoline JF, Jacobson AE, Rice KC, Deschamps JR, Beck Z, Alving CR, Matyas GR. Efficacy, but Not Antibody Titer or Affinity, of a Heroin Hapten Conjugate Vaccine Correlates with Increasing Hapten Densities on Tetanus Toxoid, but Not on CRM197 Carriers. Bioconjugate Chemistry. 26: 1041-53. PMID 25970207 DOI: 10.1021/Acs.Bioconjchem.5B00085  0.96
2015 Blasio A, Valenza M, Iyer MR, Rice KC, Steardo L, Hayashi T, Cottone P, Sabino V. Sigma-1 receptor mediates acquisition of alcohol drinking and seeking behavior in alcohol-preferring rats. Behavioural Brain Research. 287: 315-22. PMID 25848705 DOI: 10.1016/J.Bbr.2015.03.065  0.96
2015 Grace PM, Shimizu K, Strand KA, Rice KC, Deng G, Watkins LR, Herson PS. (+)-Naltrexone is neuroprotective and promotes alternative activation in the mouse hippocampus after cardiac arrest/cardiopulmonary resuscitation. Brain, Behavior, and Immunity. 48: 115-22. PMID 25774010 DOI: 10.1016/J.Bbi.2015.03.005  0.96
2015 Suzuki M, Deschamps JR, Jacobson AE, Rice KC. Chiral resolution and absolute configuration of the enantiomers of the psychoactive "designer drug" 3,4-methylenedioxypyrovalerone. Chirality. 27: 287-93. PMID 25727807 DOI: 10.1002/Chir.22423  0.96
2015 Fink LH, Anastasio NC, Fox RG, Rice KC, Moeller FG, Cunningham KA. Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1957-68. PMID 25666313 DOI: 10.1038/Npp.2015.46  0.96
2015 Zhang C, Kuo CC, Moghadam SH, Monte L, Rice KC, Rissman RA. Corticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer’s Disease Transgenic Mouse Model. Journal of Alzheimer's Disease : Jad. 45: 639-50. PMID 25649650 DOI: 10.3233/Jad-141722  0.72
2015 Northcutt AL, Hutchinson MR, Wang X, Baratta MV, Hiranita T, Cochran TA, Pomrenze MB, Galer EL, Kopajtic TA, Li CM, Amat J, Larson G, Cooper DC, Huang Y, O'Neill CE, ... ... Rice KC, et al. DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. Molecular Psychiatry. PMID 25644383 DOI: 10.1038/Mp.2014.177  0.96
2015 Iyer MR, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena 49. N-substituted rac-cis-4a-arylalkyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols. European Journal of Medicinal Chemistry. 92: 531-9. PMID 25599950 DOI: 10.1016/J.Ejmech.2015.01.025  0.96
2015 Hutsell BA, Cheng K, Rice KC, Negus SS, Banks ML. Effects of the kappa opioid receptor antagonist nor-binaltorphimine (nor-BNI) on cocaine versus food choice and extended-access cocaine intake in rhesus monkeys. Addiction Biology. PMID 25581305 DOI: 10.1111/Adb.12206  0.72
2015 Corrigan F, Wu Y, Tuke J, Coller JK, Rice KC, Diener KR, Hayball JD, Watkins LR, Somogyi AA, Hutchinson MR. Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling. Brain, Behavior, and Immunity. 45: 245-52. PMID 25542736 DOI: 10.1016/J.Bbi.2014.12.019  0.96
2015 King HE, Wetzell B, Rice KC, Riley AL. An assessment of MDPV-induced place preference in adult Sprague-Dawley rats. Drug and Alcohol Dependence. 146: 116-9. PMID 25468817 DOI: 10.1016/J.Drugalcdep.2014.11.002  0.96
2015 Altarifi AA, Rice KC, Negus SS. Effects of μ-opioid receptor agonists in assays of acute pain-stimulated and pain-depressed behavior in male rats: role of μ-agonist efficacy and noxious stimulus intensity. The Journal of Pharmacology and Experimental Therapeutics. 352: 208-17. PMID 25406170 DOI: 10.1124/Jpet.114.219873  0.72
2015 Lewis SS, Hutchinson MR, Frick MM, Zhang Y, Maier SF, Sammakia T, Rice KC, Watkins LR. Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain. Brain, Behavior, and Immunity. 44: 128-36. PMID 25218902 DOI: 10.1016/J.Bbi.2014.09.004  0.72
2015 Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's Disease : Jad. 43: 967-76. PMID 25125464 DOI: 10.3233/Jad-141281  0.72
2015 Carbonaro TM, Eshleman AJ, Forster MJ, Cheng K, Rice KC, Gatch MB. The role of 5-HT2A, 5-HT 2C and mGlu2 receptors in the behavioral effects of tryptamine hallucinogens N,N-dimethyltryptamine and N,N-diisopropyltryptamine in rats and mice. Psychopharmacology. 232: 275-84. PMID 24985890 DOI: 10.1007/S00213-014-3658-3  0.96
2015 Schank JR, Nelson BS, Damadzic R, Tapocik JD, Yao M, King CE, Rowe KE, Cheng K, Rice KC, Heilig M. Neurokinin-1 receptor antagonism attenuates neuronal activity triggered by stress-induced reinstatement of alcohol seeking Neuropharmacology. 99: 106-114. DOI: 10.1016/j.neuropharm.2015.07.009  0.72
2015 Ellefsen KN, Concheiro M, Suzuki M, Rice KC, Elmore JS, Baumann MH, Huestis MA. Quantification of methylone and metabolites in rat and human plasma by liquid chromatography-tandem mass spectrometry Forensic Toxicology. 33: 202-212. DOI: 10.1007/S11419-015-0263-Z  0.52
2015 Bachtell R, Hutchinson MR, Wang X, Rice KC, Maier SF, Watkins LR. Targeting the toll of drug abuse: The translational potential of toll-like receptor 4 Cns and Neurological Disorders - Drug Targets. 14: 692-698.  0.96
2014 Anizan S, Concheiro M, Lehner KR, Bukhari MO, Suzuki M, Rice KC, Baumann MH, Huestis MA. Linear pharmacokinetics of 3,4-methylenedioxypyrovalerone (MDPV) and its metabolites in the rat: relationship to pharmacodynamic effects. Addiction Biology. PMID 25475011 DOI: 10.1111/Adb.12201  0.52
2014 King HE, Wetzell B, Rice KC, Riley AL. 3,4-methylenedioxypyrovalerone (MDPV)-induced conditioned taste avoidance in the F344/N and LEW rat strains. Pharmacology, Biochemistry, and Behavior. 126: 163-9. PMID 25284129 DOI: 10.1016/J.Pbb.2014.09.021  0.96
2014 Leitl MD, Potter DN, Cheng K, Rice KC, Carlezon WA, Negus SS. Sustained pain-related depression of behavior: effects of intraplantar formalin and complete freund's adjuvant on intracranial self-stimulation (ICSS) and endogenous kappa opioid biomarkers in rats. Molecular Pain. 10: 62. PMID 25245060 DOI: 10.1186/1744-8069-10-62  0.96
2014 Grace PM, Ramos KM, Rodgers KM, Wang X, Hutchinson MR, Lewis MT, Morgan KN, Kroll JL, Taylor FR, Strand KA, Zhang Y, Berkelhammer D, Huey MG, Greene LI, Cochran TA, ... ... Rice KC, et al. Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae. Neuroscience. 280: 299-317. PMID 25241065 DOI: 10.1016/J.Neuroscience.2014.09.020  0.96
2014 Micioni Di Bonaventura MV, Ciccocioppo R, Romano A, Bossert JM, Rice KC, Ubaldi M, St Laurent R, Gaetani S, Massi M, Shaham Y, Cifani C. Role of bed nucleus of the stria terminalis corticotrophin-releasing factor receptors in frustration stress-induced binge-like palatable food consumption in female rats with a history of food restriction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11316-24. PMID 25143612 DOI: 10.1523/Jneurosci.1854-14.2014  0.96
2014 Zwicker JD, Zhang Y, Ren J, Hutchinson MR, Rice KC, Watkins LR, Greer JJ, Funk GD. Glial TLR4 signaling does not contribute to opioid-induced depression of respiration. Journal of Applied Physiology (Bethesda, Md. : 1985). 117: 857-68. PMID 25103966 DOI: 10.1152/Japplphysiol.00534.2014  0.96
2014 Torres OB, Jalah R, Rice KC, Li F, Antoline JF, Iyer MR, Jacobson AE, Boutaghou MN, Alving CR, Matyas GR. Characterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines. Analytical and Bioanalytical Chemistry. 406: 5927-37. PMID 25084736 DOI: 10.1007/S00216-014-8035-X  0.96
2014 Blasio A, Rice KC, Sabino V, Cottone P. Characterization of a shortened model of diet alternation in female rats: effects of the CB1 receptor antagonist rimonabant on food intake and anxiety-like behavior. Behavioural Pharmacology. 25: 609-17. PMID 25011007 DOI: 10.1097/Fbp.0000000000000059  0.96
2014 Li F, Cheng K, Antoline JF, Iyer MR, Matyas GR, Torres OB, Jalah R, Beck Z, Alving CR, Parrish DA, Deschamps JR, Jacobson AE, Rice KC. Synthesis and immunological effects of heroin vaccines. Organic & Biomolecular Chemistry. 12: 7211-32. PMID 24995943 DOI: 10.1039/C4Ob01053A  0.96
2014 Mabrouk OS, Dripps IJ, Ramani S, Chang C, Han JL, Rice KC, Jutkiewicz EM. Automated touch screen device for recording complex rodent behaviors. Journal of Neuroscience Methods. 233: 129-36. PMID 24952323 DOI: 10.1016/J.Jneumeth.2014.05.004  0.96
2014 Dong H, Wang S, Zeng Z, Li F, Montalvo-Ortiz J, Tucker C, Akhtar S, Shi J, Meltzer HY, Rice KC, Csernansky JG. Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice. Psychopharmacology. 231: 4711-22. PMID 24862368 DOI: 10.1007/S00213-014-3629-8  0.96
2014 Augier E, Flanigan M, Dulman RS, Pincus A, Schank JR, Rice KC, Kejun C, Heilig M, Tapocik JD. Wistar rats acquire and maintain self-administration of 20 % ethanol without water deprivation, saccharin/sucrose fading, or extended access training. Psychopharmacology. 231: 4561-8. PMID 24858375 DOI: 10.1007/S00213-014-3605-3  0.96
2014 Anizan S, Ellefsen K, Concheiro M, Suzuki M, Rice KC, Baumann MH, Huestis MA. 3,4-Methylenedioxypyrovalerone (MDPV) and metabolites quantification in human and rat plasma by liquid chromatography-high resolution mass spectrometry. Analytica Chimica Acta. 827: 54-63. PMID 24832995 DOI: 10.1016/J.Aca.2014.04.015  0.52
2014 Selfridge BR, Deschamps JR, Jacobson AE, Rice KC. Synthesis of enantiopure 10-nornaltrexones in the search for Toll-like receptor 4 antagonists and opioid ligands. The Journal of Organic Chemistry. 79: 5007-18. PMID 24773391 DOI: 10.1021/Jo500568S  0.96
2014 Bajo M, Madamba SG, Roberto M, Blednov YA, Sagi VN, Roberts E, Rice KC, Harris RA, Siggins GR. Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala. Brain, Behavior, and Immunity. 40: 191-202. PMID 24675033 DOI: 10.1016/J.Bbi.2014.03.007  0.96
2014 Matyas GR, Rice KC, Cheng K, Li F, Antoline JF, Iyer MR, Jacobson AE, Mayorov AV, Beck Z, Torres OB, Alving CR. Facial recognition of heroin vaccine opiates: type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine. Vaccine. 32: 1473-9. PMID 24486371 DOI: 10.1016/J.Vaccine.2014.01.028  0.96
2014 Kupchik YM, Scofield MD, Rice KC, Cheng K, Roques BP, Kalivas PW. Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1057-66. PMID 24431463 DOI: 10.1523/Jneurosci.4336-13.2014  0.96
2014 Ellis A, Wieseler J, Favret J, Johnson KW, Rice KC, Maier SF, Falci S, Watkins LR. Systemic administration of propentofylline, ibudilast, and (+)-naltrexone each reverses mechanical allodynia in a novel rat model of central neuropathic pain. The Journal of Pain : Official Journal of the American Pain Society. 15: 407-21. PMID 24412802 DOI: 10.1016/J.Jpain.2013.12.007  0.96
2014 Xiong W, Chen SR, He L, Cheng K, Zhao YL, Chen H, Li DP, Homanics GE, Peever J, Rice KC, Wu LG, Pan HL, Zhang L. Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease. Nature Neuroscience. 17: 232-9. PMID 24390226 DOI: 10.1038/Nn.3615  0.96
2014 Sukhtankar DD, Lee H, Rice KC, Ko MC. Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain Psychopharmacology. 231: 1377-1387. PMID 24217900 DOI: 10.1007/S00213-013-3341-0  0.96
2014 Schank JR, King CE, Sun H, Cheng K, Rice KC, Heilig M, Weinshenker D, Schroeder JP. The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1093-101. PMID 24173499 DOI: 10.1038/Npp.2013.309  0.96
2014 Merluzzi AP, Hurwitz ZE, Briscione MA, Cobuzzi JL, Wetzell B, Rice KC, Riley AL. Age-dependent MDPV-induced taste aversions and thermoregulation in adolescent and adult rats. Developmental Psychobiology. 56: 943-54. PMID 24122728 DOI: 10.1002/Dev.21171  0.96
2014 Leitl MD, Onvani S, Bowers MS, Cheng K, Rice KC, Carlezon WA, Banks ML, Negus SS. Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 614-24. PMID 24008352 DOI: 10.1038/Npp.2013.236  0.96
2014 Dore R, Valenza M, Wang X, Rice KC, Sabino V, Cottone P. The inverse agonist of CB1 receptor SR141716 blocks compulsive eating of palatable food. Addiction Biology. 19: 849-61. PMID 23587012 DOI: 10.1111/Adb.12056  0.96
2014 Anizan S, Ellefsen K, Concheiro M, Suzuki M, Rice KC, Baumann MH, Huestis MA. 3,4-Methylenedioxypyrovalerone (MDPV) and metabolites quantification in human and rat plasma by liquid chromatography-high resolution mass spectrometry Analytica Chimica Acta. 827: 54-63. DOI: 10.1016/j.aca.2014.04.015  0.96
2013 Murnane KS, Winschel J, Schmidt KT, Stewart LM, Rose SJ, Cheng K, Rice KC, Howell LL. Serotonin 2A receptors differentially contribute to abuse-related effects of cocaine and cocaine-induced nigrostriatal and mesolimbic dopamine overflow in nonhuman primates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13367-74. PMID 23946394 DOI: 10.1523/Jneurosci.1437-13.2013  0.96
2013 Altarifi AA, Rice KC, Negus SS. Abuse-related effects of μ-opioid analgesics in an assay of intracranial self-stimulation in rats: Modulation by chronic morphine exposure Behavioural Pharmacology. 24: 459-470. PMID 23881045 DOI: 10.1097/Fbp.0B013E328364C0Bd  0.96
2013 Lim HJ, Dersch CM, Rothman RB, Deschamps JR, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 48. C7- and C8-substituted 5-phenylmorphan opioids from diastereoselective alkylation. European Journal of Medicinal Chemistry. 67: 335-43. PMID 23880358 DOI: 10.1016/J.Ejmech.2013.06.030  0.96
2013 Murnane KS, Andersen ML, Rice KC, Howell LL. Selective serotonin 2A receptor antagonism attenuates the effects of amphetamine on arousal and dopamine overflow in non-human primates. Journal of Sleep Research. 22: 581-8. PMID 23879373 DOI: 10.1111/Jsr.12045  0.96
2013 Blasio A, Iemolo A, Sabino V, Petrosino S, Steardo L, Rice KC, Orlando P, Iannotti FA, Di Marzo V, Zorrilla EP, Cottone P. Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2498-507. PMID 23793355 DOI: 10.1038/Npp.2013.153  0.96
2013 Iemolo A, Blasio A, St Cyr SA, Jiang F, Rice KC, Sabino V, Cottone P. CRF-CRF1 receptor system in the central and basolateral nuclei of the amygdala differentially mediates excessive eating of palatable food. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2456-66. PMID 23748225 DOI: 10.1038/Npp.2013.147  0.96
2013 Li W, Shi X, Wang L, Guo T, Wei T, Cheng K, Rice KC, Kingery WS, Clark JD. Epidermal adrenergic signaling contributes to inflammation and pain sensitization in a rat model of complex regional pain syndrome. Pain. 154: 1224-36. PMID 23718987 DOI: 10.1016/J.Pain.2013.03.033  0.96
2013 Gatch MB, Kozlenkov A, Huang RQ, Yang W, Nguyen JD, González-Maeso J, Rice KC, France CP, Dillon GH, Forster MJ, Schetz JA. The HIV antiretroviral drug efavirenz has LSD-like properties. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2373-84. PMID 23702798 DOI: 10.1038/Npp.2013.135  0.96
2013 Matyas GR, Mayorov AV, Rice KC, Jacobson AE, Cheng K, Iyer MR, Li F, Beck Z, Janda KD, Alving CR. Liposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs. Vaccine. 31: 2804-10. PMID 23624097 DOI: 10.1016/J.Vaccine.2013.04.027  0.96
2013 Iyer MR, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 47. Novel C4a- and N-substituted-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols. Bioorganic & Medicinal Chemistry. 21: 3298-309. PMID 23618710 DOI: 10.1016/J.Bmc.2013.02.060  0.96
2013 Birdsong WT, Arttamangkul S, Clark MJ, Cheng K, Rice KC, Traynor JR, Williams JT. Increased agonist affinity at the μ-opioid receptor induced by prolonged agonist exposure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4118-27. PMID 23447620 DOI: 10.1523/Jneurosci.4187-12.2013  0.96
2013 Schank JR, Tapocik JD, Barbier E, Damadzic R, Eskay RL, Sun H, Rowe KE, King CE, Yao M, Flanigan ME, Solomon MG, Karlsson C, Cheng K, Rice KC, Heilig M. Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats. Biological Psychiatry. 73: 774-81. PMID 23419547 DOI: 10.1016/J.Biopsych.2012.12.027  0.96
2013 Briscione MA, Serafine KM, Merluzzi AP, Rice KC, Riley AL. The effects of the 5-HT3 receptor antagonist tropisetron on cocaine-induced conditioned taste aversions. Pharmacology, Biochemistry, and Behavior. 105: 112-7. PMID 23415734 DOI: 10.1016/J.Pbb.2013.02.003  0.96
2013 Theberge FR, Li X, Kambhampati S, Pickens CL, St Laurent R, Bossert JM, Baumann MH, Hutchinson MR, Rice KC, Watkins LR, Shaham Y. Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving. Biological Psychiatry. 73: 729-37. PMID 23384483 DOI: 10.1016/J.Biopsych.2012.12.019  0.96
2013 Lewis SS, Hutchinson MR, Zhang Y, Hund DK, Maier SF, Rice KC, Watkins LR. Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain. Brain, Behavior, and Immunity. 30: 24-32. PMID 23348028 DOI: 10.1016/J.Bbi.2013.01.005  0.96
2013 Cunningham KA, Anastasio NC, Fox RG, Stutz SJ, Bubar MJ, Swinford SE, Watson CS, Gilbertson SR, Rice KC, Rosenzweig-Lipson S, Moeller FG. Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction. Acs Chemical Neuroscience. 4: 110-21. PMID 23336050 DOI: 10.1021/Cn300072U  0.96
2013 Jutkiewicz EM, Rice KC, Carroll FI, Woods JH. Patterns of nicotinic receptor antagonism II: cardiovascular effects in rats. Drug and Alcohol Dependence. 131: 284-97. PMID 23333294 DOI: 10.1016/J.Drugalcdep.2012.12.021  0.96
2013 Barbier E, Vendruscolo LF, Schlosburg JE, Edwards S, Juergens N, Park PE, Misra KK, Cheng K, Rice KC, Schank J, Schulteis G, Koob GF, Heilig M. The NK1 receptor antagonist L822429 reduces heroin reinforcement. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 976-84. PMID 23303056 DOI: 10.1038/Npp.2012.261  0.96
2013 Koek W, Cheng K, Rice KC. Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: Comparison with GABAB receptor agonists and drugs of abuse Journal of Pharmacology and Experimental Therapeutics. 344: 553-560. PMID 23275067 DOI: 10.1124/Jpet.112.202226  0.96
2013 Sulima A, Cheng K, Jacobson AE, Rice KC, Gawrisch K, Lee YS. Z and e rotamers of N-formyl-1-bromo-4-hydroxy-3-methoxymorphinan-6-one and their interconversion as studied by 1H/13C NMR spectroscopy and quantum chemical calculations Magnetic Resonance in Chemistry. 51: 82-88. PMID 23233124 DOI: 10.1002/Mrc.3909  0.96
2013 Fantegrossi WE, Gannon BM, Zimmerman SM, Rice KC. In vivo effects of abused 'bath salt' constituent 3,4- methylenedioxypyrovalerone (MDPV) in mice: Drug discrimination, thermoregulation, and locomotor activity Neuropsychopharmacology. 38: 563-573. PMID 23212455 DOI: 10.1038/Npp.2012.233  0.96
2013 Sabino V, Kwak J, Rice KC, Cottone P. Pharmacological characterization of the 20% alcohol intermittent access model in Sardinian alcohol-preferring rats: a model of binge-like drinking. Alcoholism, Clinical and Experimental Research. 37: 635-43. PMID 23126554 DOI: 10.1111/Acer.12008  0.96
2013 Li JX, Shah AP, Patel SK, Rice KC, France CP. Modification of the behavioral effects of morphine in rats by serotonin 5-HT₁A and 5-HTâ‚‚A receptor agonists: antinociception, drug discrimination, and locomotor activity. Psychopharmacology. 225: 791-801. PMID 22993050 DOI: 10.1007/S00213-012-2870-2  0.96
2012 Guo TZ, Wei T, Shi X, Li WW, Hou S, Wang L, Tsujikawa K, Rice KC, Cheng K, Clark DJ, Kingery WS. Neuropeptide deficient mice have attenuated nociceptive, vascular, and inflammatory changes in a tibia fracture model of complex regional pain syndrome. Molecular Pain. 8: 85. PMID 23191958 DOI: 10.1186/1744-8069-8-85  0.96
2012 Li F, Deck JA, Dersch CM, Rothman RB, Deschamps JR, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 46. N-substituted-2,3,4,9, 10,10a-hexahydro-1H-1,4a-(epiminoethano)phenanthren-6- and 8-ols - Carbocyclic relatives of f-oxide-bridged phenylmorphans European Journal of Medicinal Chemistry. 58: 557-567. PMID 23168379 DOI: 10.1016/J.Ejmech.2012.10.041  0.96
2012 Yekkirala AS, Banks ML, Lunzer MM, Negus SS, Rice KC, Portoghese PS. Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys. Acs Chemical Neuroscience. 3: 720-7. PMID 23019498 DOI: 10.1021/Cn300049M  0.96
2012 Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, ... ... Rice KC, et al. Opioid activation of toll-like receptor 4 contributes to drug reinforcement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11187-200. PMID 22895704 DOI: 10.1523/Jneurosci.0684-12.2012  0.96
2012 Tam J, Cinar R, Liu J, Godlewski G, Wesley D, Jourdan T, Szanda G, Mukhopadhyay B, Chedester L, Liow JS, Innis RB, Cheng K, Rice KC, Deschamps JR, Chorvat RJ, et al. Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance Cell Metabolism. 16: 167-179. PMID 22841573 DOI: 10.1016/J.Cmet.2012.07.002  0.96
2012 Koffarnus MN, Collins GT, Rice KC, Chen J, Woods JH, Winger G. Self-administration of agonists selective for dopamine D2, D3, and D4 receptors by rhesus monkeys. Behavioural Pharmacology. 23: 331-8. PMID 22785383 DOI: 10.1097/Fbp.0B013E3283564Dbb  0.96
2012 Parylak SL, Cottone P, Sabino V, Rice KC, Zorrilla EP. Effects of CB1 and CRF1 receptor antagonists on binge-like eating in rats with limited access to a sweet fat diet: lack of withdrawal-like responses. Physiology & Behavior. 107: 231-42. PMID 22776620 DOI: 10.1016/J.Physbeh.2012.06.017  0.96
2012 Cottone P, Wang X, Park JW, Valenza M, Blasio A, Kwak J, Iyer MR, Steardo L, Rice KC, Hayashi T, Sabino V. Antagonism of sigma-1 receptors blocks compulsive-like eating. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2593-604. PMID 22713906 DOI: 10.1038/Npp.2012.89  0.96
2012 Negus SS, Morrissey EM, Folk JE, Rice KC. Interaction between Mu and Delta Opioid Receptor Agonists in an Assay of Capsaicin-Induced Thermal Allodynia in Rhesus Monkeys. Pain Research and Treatment. 2012: 867067. PMID 22666579 DOI: 10.1155/2012/867067  0.52
2012 Serafine KM, Briscione MA, Rice KC, Riley AL. Dopamine mediates cocaine-induced conditioned taste aversions as demonstrated with cross-drug preexposure to GBR 12909. Pharmacology, Biochemistry, and Behavior. 102: 269-74. PMID 22579912 DOI: 10.1016/J.Pbb.2012.04.012  0.96
2012 Lewis SS, Loram LC, Hutchinson MR, Li CM, Zhang Y, Maier SF, Huang Y, Rice KC, Watkins LR. (+)-naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats. The Journal of Pain : Official Journal of the American Pain Society. 13: 498-506. PMID 22520687 DOI: 10.1016/J.Jpain.2012.02.005  0.96
2012 Rissman RA, Staup MA, Lee AR, Justice NJ, Rice KC, Vale W, Sawchenko PE. Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation. Proceedings of the National Academy of Sciences of the United States of America. 109: 6277-82. PMID 22451915 DOI: 10.1073/Pnas.1203140109  0.96
2012 Sawyer EK, Mun J, Nye JA, Kimmel HL, Voll RJ, Stehouwer JS, Rice KC, Goodman MM, Howell LL. Neurobiological changes mediating the effects of chronic fluoxetine on cocaine use. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1816-24. PMID 22434223 DOI: 10.1038/Npp.2012.29  0.96
2012 Negus SS, Rosenberg MB, Altarifi AA, O'Connell RH, Folk JE, Rice KC. Effects of the delta opioid receptor agonist SNC80 on pain-related depression of intracranial self-stimulation (ICSS) in rats Journal of Pain. 13: 317-327. PMID 22424913 DOI: 10.1016/J.Jpain.2011.12.003  0.96
2012 Boos TL, Cheng K, Greiner E, Deschamps JR, Jacobson AE, Rice KC. Configurational reassignment and improved preparation of the competitive IL-6 receptor antagonist 20 R,21 R-epoxyresibufogenin-3-formate Journal of Natural Products. 75: 661-668. PMID 22360661 DOI: 10.1021/Np2008957  0.96
2012 Iyer MR, Lee YS, Deschamps JR, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity. European Journal of Medicinal Chemistry. 50: 44-54. PMID 22341895 DOI: 10.1016/J.Ejmech.2012.01.025  0.96
2012 Koek W, France CP, Cheng K, Rice KC. Effects of the GABAB receptor-positive modulators CGP7930 and rac-BHFF in baclofen- and γ-hydroxybutyrate-discriminating pigeons. The Journal of Pharmacology and Experimental Therapeutics. 341: 369-76. PMID 22319197 DOI: 10.1124/Jpet.111.190975  0.96
2012 Murnane KS, Kimmel HL, Rice KC, Howell LL. The neuropharmacology of prolactin secretion elicited by 3,4-methylenedioxymethamphetamine ("ecstasy"): a concurrent microdialysis and plasma analysis study. Hormones and Behavior. 61: 181-90. PMID 22197270 DOI: 10.1016/J.Yhbeh.2011.10.012  0.96
2012 Kimura T, Yeliseev AA, Vukoti K, Rhodes SD, Cheng K, Rice KC, Gawrisch K. Recombinant cannabinoid type 2 receptor in liposome model activates g protein in response to anionic lipid constituents. The Journal of Biological Chemistry. 287: 4076-87. PMID 22134924 DOI: 10.1074/Jbc.M111.268425  0.96
2012 Negus SS, O'Connell R, Morrissey E, Cheng K, Rice KC. Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in rats Journal of Pharmacology and Experimental Therapeutics. 340: 501-509. PMID 22128346 DOI: 10.1124/Jpet.111.186783  0.96
2012 Wu Y, Lousberg EL, Moldenhauer LM, Hayball JD, Coller JK, Rice KC, Watkins LR, Somogyi AA, Hutchinson MR. Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice. British Journal of Pharmacology. 165: 1319-29. PMID 21955045 DOI: 10.1111/J.1476-5381.2011.01572.X  0.96
2012 Hensler JG, Advani T, Burke TF, Cheng K, Rice KC, Koek W. GABAB receptor-positive modulators: brain region-dependent effects. The Journal of Pharmacology and Experimental Therapeutics. 340: 19-26. PMID 21954301 DOI: 10.1124/Jpet.111.186577  0.96
2012 Negus SS, Morrissey EM, Folk JE, Rice KC. Interaction between mu and delta opioid receptor agonists in an assay of capsaicin-induced thermal allodynia in rhesus monkeys Pain Research and Treatment. 2012. DOI: 10.1155/2012/867067  0.96
2011 Lim HJ, Deschamps JR, Jacobson AE, Rice KC. Diastereoselective One-Pot Synthesis of 7- and 8-Substituted 5-Phenylmorphans Organic Letters. 13: 5322-5325. PMID 21905747 DOI: 10.1021/Ol2021862  0.96
2011 Hutchinson MR, Shavit Y, Grace PM, Rice KC, Maier SF, Watkins LR. Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacological Reviews. 63: 772-810. PMID 21752874 DOI: 10.1124/Pr.110.004135  0.96
2011 Jutkiewicz EM, Brooks EA, Kynaston AD, Rice KC, Woods JH. Patterns of nicotinic receptor antagonism: nicotine discrimination studies. The Journal of Pharmacology and Experimental Therapeutics. 339: 194-202. PMID 21730011 DOI: 10.1124/Jpet.111.182170  0.96
2011 Koffarnus MN, Newman AH, Grundt P, Rice KC, Woods JH. Effects of selective dopaminergic compounds on a delay-discounting task. Behavioural Pharmacology. 22: 300-11. PMID 21694584 DOI: 10.1097/Fbp.0B013E3283473Bcb  0.96
2011 Li F, Folk JE, Cheng K, Kurimura M, Deck JA, Deschamps JR, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: compounds with moderate to low opioid-receptor affinity. Bioorganic & Medicinal Chemistry. 19: 4330-7. PMID 21684752 DOI: 10.1016/J.Bmc.2011.05.035  0.96
2011 Winter JC, Amorosi DJ, Rice KC, Cheng K, Yu AM. Stimulus control by 5-methoxy-N,N-dimethyltryptamine in wild-type and CYP2D6-humanized mice. Pharmacology, Biochemistry, and Behavior. 99: 311-5. PMID 21624387 DOI: 10.1016/J.Pbb.2011.05.015  0.96
2011 Kim JH, Deschamps JR, Rothman RB, Dersch CM, Folk JE, Cheng K, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. Part 42: Synthesis and in vitro pharmacological characterization of the N-methyl and N-phenethyl analogues of the racemic ortho-c and para-c oxide-bridged phenylmorphans Bioorganic and Medicinal Chemistry. 19: 3434-3443. PMID 21570305 DOI: 10.1016/J.Bmc.2011.04.028  0.96
2011 Anastasio NC, Stoffel EC, Fox RG, Bubar MJ, Rice KC, Moeller FG, Cunningham KA. Serotonin (5-hydroxytryptamine) 5-HT(2A) receptor: association with inherent and cocaine-evoked behavioral disinhibition in rats. Behavioural Pharmacology. 22: 248-61. PMID 21499079 DOI: 10.1097/Fbp.0B013E328345F90D  0.96
2011 Xiong W, Cheng K, Cui T, Godlewski G, Rice KC, Xu Y, Zhang L. Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia. Nature Chemical Biology. 7: 296-303. PMID 21460829 DOI: 10.1038/Nchembio.552  0.96
2011 Banks ML, Roma PG, Folk JE, Rice KC, Negus SS. Effects of the delta-opioid agonist SNC80 on the abuse liability of methadone in rhesus monkeys: a behavioral economic analysis. Psychopharmacology. 216: 431-9. PMID 21369752 DOI: 10.1007/S00213-011-2235-2  0.96
2011 Sabino V, Cottone P, Blasio A, Iyer MR, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP. Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1207-18. PMID 21346735 DOI: 10.1038/Npp.2011.5  0.96
2011 Schank JR, Pickens CL, Rowe KE, Cheng K, Thorsell A, Rice KC, Shaham Y, Heilig M. Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429. Psychopharmacology. 218: 111-9. PMID 21340476 DOI: 10.1007/S00213-011-2201-Z  0.96
2011 Jagoda EM, Lang L, Mccullough K, Contoreggi C, Kim BM, Ma Y, Rice KC, Szajek LP, Eckelman WC, Kiesewetter DO. [76Br]BMK-152, a nonpeptide analogue, with high affinity and low nonspecific binding for the corticotropin-releasing factor type 1 receptor Synapse. 65: 910-918. PMID 21308801 DOI: 10.1002/Syn.20919  0.96
2011 Cheng K, Lee YS, Rothman RB, Dersch CM, Bittman RW, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 41. Unusual inverse μ-agonists and potent μ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphans Journal of Medicinal Chemistry. 54: 957-969. PMID 21247164 DOI: 10.1021/Jm1011676  0.96
2011 Li JX, Koek W, Rice KC, France CP. Effects of direct- and indirect-acting serotonin receptor agonists on the antinociceptive and discriminative stimulus effects of morphine in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 940-9. PMID 21209613 DOI: 10.1038/Npp.2010.232  0.96
2011 Li JX, Crocker C, Koek W, Rice KC, France CP. Effects of serotonin (5-HT)1A and 5-HT2A receptor agonists on schedule-controlled responding in rats: drug combination studies. Psychopharmacology. 213: 489-97. PMID 21174080 DOI: 10.1007/S00213-010-2136-9  0.96
2011 Kimura T, Yeliseev A, Mihailescu M, Cheng K, Rice KC, Gawrisch K. Solid-State NMR Study of Ligand Binding to Human Peripheral Cannabinoid Receptor CB2 Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3202  0.84
2010 Fantegrossi WE, Simoneau J, Cohen MS, Zimmerman SM, Henson CM, Rice KC, Woods JH. Interaction of 5-HT2A and 5-HT2C receptors in R(-)-2,5-dimethoxy-4-iodoamphetamine-elicited head twitch behavior in mice. The Journal of Pharmacology and Experimental Therapeutics. 335: 728-34. PMID 20858706 DOI: 10.1124/Jpet.110.172247  0.96
2010 Rothman RB, Baumann MH, Blough BE, Jacobson AE, Rice KC, Partilla JS. Evidence for noncompetitive modulation of substrate-induced serotonin release Synapse. 64: 862-869. PMID 20842720 DOI: 10.1002/syn.20804  0.96
2010 Banks ML, Folk JE, Rice KC, Negus SS. Selective enhancement of fentanyl-induced antinociception by the delta agonist SNC162 but not by ketamine in rhesus monkeys: Further evidence supportive of delta agonists as candidate adjuncts to mu opioid analgesics. Pharmacology, Biochemistry, and Behavior. 97: 205-12. PMID 20678514 DOI: 10.1016/J.Pbb.2010.07.019  0.96
2010 Banks ML, Rice KC, Negus SS. Antinociceptive interactions between Mu-opioid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy. The Journal of Pharmacology and Experimental Therapeutics. 335: 497-505. PMID 20675432 DOI: 10.1124/Jpet.110.169276  0.96
2010 Koek W, France CP, Cheng K, Rice KC. GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo. The Journal of Pharmacology and Experimental Therapeutics. 335: 163-71. PMID 20628000 DOI: 10.1124/Jpet.110.171116  0.96
2010 Vardanyan M, Melemedjian OK, Price TJ, Ossipov MH, Lai J, Roberts E, Boos TL, Deschamps JR, Jacobson AE, Rice KC, Porreca F. Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist. Pain. 151: 257-65. PMID 20599324 DOI: 10.1016/J.Pain.2010.05.022  0.96
2010 De Bruyne S, Wyffels L, Boos TL, Staelens S, Deleye S, Rice KC, De Vos F. In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter Nuclear Medicine and Biology. 37: 469-477. PMID 20447559 DOI: 10.1016/J.Nucmedbio.2009.10.006  0.96
2010 Hutchinson MR, Loram LC, Zhang Y, Shridhar M, Rezvani N, Berkelhammer D, Phipps S, Foster PS, Landgraf K, Falke JJ, Rice KC, Maier SF, Yin H, Watkins LR. Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity. Neuroscience. 168: 551-63. PMID 20381591 DOI: 10.1016/J.Neuroscience.2010.03.067  0.96
2010 Hutchinson MR, Lewis SS, Coats BD, Rezvani N, Zhang Y, Wieseler JL, Somogyi AA, Yin H, Maier SF, Rice KC, Watkins LR. Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences. Neuroscience. 167: 880-93. PMID 20178837 DOI: 10.1016/J.Neuroscience.2010.02.011  0.96
2010 Negus SS, Morrissey EM, Rosenberg M, Cheng K, Rice KC. Effects of kappa opioids in an assay of pain-depressed intracranial self-stimulation in rats Psychopharmacology. 209: 149-159. PMID 20101391 DOI: 10.1007/S00213-009-1770-6  0.96
2010 Negus SS, Banks ML, Folk JE, Rice KC. Modulation of delta opioid agonist-induced antinociception by repeated morphine pretreatment in rhesus monkeys. Life Sciences. 86: 385-92. PMID 20096291 DOI: 10.1016/J.Lfs.2010.01.006  0.96
2010 Li JX, Koek W, Rice KC, France CP. Differential effects of serotonin 5-HT1A receptor agonists on the discriminative stimulus effects of the 5-HT2A receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rats and rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 333: 244-52. PMID 20053932 DOI: 10.1124/Jpet.109.163451  0.96
2010 Iyer MR, Lee YS, Deschamps JR, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 40. N-substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ols. Bioorganic & Medicinal Chemistry. 18: 91-9. PMID 20005115 DOI: 10.1016/J.Bmc.2009.11.022  0.96
2010 Sally EJ, Xu H, Dersch CM, Hsin LW, Chang LT, Prisinzano TE, Simpson DS, Giuvelis D, Rice KC, Jacobson AE, Cheng K, Bilsky EJ, Rothman RB. Identification of a novel "almost neutral" micro-opioid receptor antagonist in CHO cells expressing the cloned human mu-opioid receptor. Synapse (New York, N.Y.). 64: 280-8. PMID 19953652 DOI: 10.1002/Syn.20723  0.96
2010 Lewis SS, Hutchinson MR, Rezvani N, Loram LC, Zhang Y, Maier SF, Rice KC, Watkins LR. Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta. Neuroscience. 165: 569-83. PMID 19833175 DOI: 10.1016/J.Neuroscience.2009.10.011  0.96
2010 Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, ... ... Rice KC, et al. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain, Behavior, and Immunity. 24: 83-95. PMID 19679181 DOI: 10.1016/J.Bbi.2009.08.004  0.92
2010 Linders JTM, Furlano DC, Mattson MV, Jacobson AE, Rice KC. Synthesis and preliminary biochemical evaluation of novel derivatives of PCP Letters in Drug Design and Discovery. 7: 79-87. DOI: 10.2174/157018010790225813  0.96
2009 Iyer MR, Deschamps JR, Jacobson AE, Rice KC. PROBES FOR NARCOTIC RECEPTOR MEDIATED PHENOMENA. 38. AN EXPEDITIOUS SYNTHESIS OF RAC-CIS-4a-ETHYL-2-METHYL-1,2,3,4,4a,9a-HEXAHYDROBENZOFURO[2,3-c]PYRIDIN-6-OL AND RAC-CIS-2-METHYL-4a-PHENETHYL-1,2,3,4,4a,9a-HEXAHYDROBENZOFURO[2,3-c]PYRIDIN-6-OL. Heterocycles. 79: 1061. PMID 20101277 DOI: 10.3987/Com-09-S(D)84  0.96
2009 Cottone P, Sabino V, Roberto M, Bajo M, Pockros L, Frihauf JB, Fekete EM, Steardo L, Rice KC, Grigoriadis DE, Conti B, Koob GF, Zorrilla EP. CRF system recruitment mediates dark side of compulsive eating. Proceedings of the National Academy of Sciences of the United States of America. 106: 20016-20. PMID 19901333 DOI: 10.1073/Pnas.0908789106  0.96
2009 Hutchinson MR, Ramos KM, Loram LC, Wieseler J, Sholar PW, Kearney JJ, Lewis MT, Crysdale NY, Zhang Y, Harrison JA, Maier SF, Rice KC, Watkins LR. Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. Neuroscience. 164: 1821-32. PMID 19788917 DOI: 10.1016/J.Neuroscience.2009.09.046  0.96
2009 Watkins LR, Hutchinson MR, Rice KC, Maier SF. The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia. Trends in Pharmacological Sciences. 30: 581-91. PMID 19762094 DOI: 10.1016/J.Tips.2009.08.002  0.96
2009 Li JX, Unzeitig A, Javors MA, Rice KC, Koek W, France CP. Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), ketanserin, and (R)-(+)-{alpha}-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol (MDL100907) in rats. The Journal of Pharmacology and Experimental Therapeutics. 331: 671-9. PMID 19687292 DOI: 10.1124/Jpet.109.157560  0.96
2009 Kreibich AS, Briand L, Cleck JN, Ecke L, Rice KC, Blendy JA. Stress-induced potentiation of cocaine reward: a role for CRF R1 and CREB. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2609-17. PMID 19675537 DOI: 10.1038/Npp.2009.91  0.96
2009 Zhang Y, Lee YS, Rothman RB, Dersch CM, Deschamps JR, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 39. Enantiomeric n-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged phenylmorphans Journal of Medicinal Chemistry. 52: 7570-7579. PMID 19627147 DOI: 10.1021/Jm9004225  0.96
2009 Klejbor I, Kucinski A, Wersinger SR, Corso T, Spodnik JH, Dziewiatkowski J, MoryÅ› J, Hesse RA, Rice KC, Miletich R, Stachowiak EK, Stachowiak MK. Serotonergic hyperinnervation and effective serotonin blockade in an FGF receptor developmental model of psychosis. Schizophrenia Research. 113: 308-21. PMID 19570652 DOI: 10.1016/J.Schres.2009.06.006  0.96
2009 Kimura T, Cheng K, Rice KC, Gawrisch K. Location, structure, and dynamics of the synthetic cannabinoid ligand CP-55,940 in lipid bilayers Biophysical Journal. 96: 4916-4924. PMID 19527650 DOI: 10.1016/J.Bpj.2009.03.033  0.96
2009 Davis CM, Rice KC, Riley AL. Opiate-agonist induced taste aversion learning in the Fischer 344 and Lewis inbred rat strains: evidence for differential mu opioid receptor activation. Pharmacology, Biochemistry, and Behavior. 93: 397-405. PMID 19508878 DOI: 10.1016/J.Pbb.2009.06.001  0.96
2009 Francesconi W, Berton F, Repunte-Canonigo V, Hagihara K, Thurbon D, Lekic D, Specio SE, Greenwell TN, Chen SA, Rice KC, Richardson HN, O'Dell LE, Zorrilla EP, Morales M, Koob GF, et al. Protracted withdrawal from alcohol and drugs of abuse impairs long-term potentiation of intrinsic excitability in the juxtacapsular bed nucleus of the stria terminalis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5389-401. PMID 19403807 DOI: 10.1523/Jneurosci.5129-08.2009  0.96
2009 Jones JD, Hall FS, Uhl GR, Rice K, Riley AL. Differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion. Pharmacology, Biochemistry, and Behavior. 93: 75-81. PMID 19376154 DOI: 10.1016/J.Pbb.2009.04.009  0.96
2009 Nic Dhonnchadha BA, Fox RG, Stutz SJ, Rice KC, Cunningham KA. Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model. Behavioral Neuroscience. 123: 382-96. PMID 19331461 DOI: 10.1037/A0014592  0.96
2009 Greenwell TN, Funk CK, Cottone P, Richardson HN, Chen SA, Rice KC, Zorrilla EP, Koob GF. Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long- but not short-access rats. Addiction Biology. 14: 130-43. PMID 19291009 DOI: 10.1111/j.1369-1600.2008.00142.x  0.96
2009 Nie Z, Zorrilla EP, Madamba SG, Rice KC, Roberto M, Siggins GR. Presynaptic CRF1 receptors mediate the ethanol enhancement of GABAergic transmission in the mouse central amygdala. Thescientificworldjournal. 9: 68-85. PMID 19151899 DOI: 10.1100/Tsw.2009.1  0.96
2009 Collins GT, Truccone A, Haji-Abdi F, Newman AH, Grundt P, Rice KC, Husbands SM, Greedy BM, Enguehard-Gueiffier C, Gueiffier A, Chen J, Wang S, Katz JL, Grandy DK, Sunahara RK, et al. Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice. The Journal of Pharmacology and Experimental Therapeutics. 329: 210-7. PMID 19136638 DOI: 10.1124/Jpet.108.144048  0.96
2009 Do Carmo GP, Folk JE, Rice KC, Chartoff E, Carlezon WA, Negus SS. The selective non-peptidic delta opioid agonist SNC80 does not facilitate intracranial self-stimulation in rats. European Journal of Pharmacology. 604: 58-65. PMID 19133255 DOI: 10.1016/J.Ejphar.2008.12.021  0.96
2009 Li JX, Rice KC, France CP. Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rhesus monkeys: antagonism and apparent pA2 analyses. The Journal of Pharmacology and Experimental Therapeutics. 328: 976-81. PMID 19098164 DOI: 10.1124/Jpet.108.145458  0.96
2009 Negus SS, Bear AE, Folk JE, Rice KC. Role of delta opioid efficacy as a determinant of mu/delta opioid interactions in rhesus monkeys. European Journal of Pharmacology. 602: 92-100. PMID 19027735 DOI: 10.1016/J.Ejphar.2008.11.004  0.96
2009 Kohut SJ, Roma PG, Davis CM, Zernig G, Saria A, Dominguez JM, Rice KC, Riley AL. The impact of early environmental rearing condition on the discriminative stimulus effects and Fos expression induced by cocaine in adult male and female rats. Psychopharmacology. 203: 383-97. PMID 18953528 DOI: 10.1007/S00213-008-1368-4  0.96
2009 Sabino V, Cottone P, Zhao Y, Iyer MR, Steardo L, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP. The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1482-93. PMID 18946467 DOI: 10.1038/Npp.2008.192  0.96
2009 May JA, Sharif NA, Chen HH, Liao JC, Kelly CR, Glennon RA, Young R, Li JX, Rice KC, France CP. Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A [(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine]. Pharmacology, Biochemistry, and Behavior. 91: 307-14. PMID 18718483 DOI: 10.1016/J.Pbb.2008.07.015  0.96
2009 Negus SS, Rice KC. Mechanisms of withdrawal-associated increases in heroin self-administration: Pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys Neuropsychopharmacology. 34: 899-911. PMID 18704098 DOI: 10.1038/Npp.2008.127  0.96
2009 Davis CM, Stevenson GW, Cañadas F, Ullrich T, Rice KC, Riley AL. Discriminative stimulus properties of naloxone in Long-Evans rats: assessment with the conditioned taste aversion baseline of drug discrimination learning. Psychopharmacology. 203: 421-9. PMID 18594795 DOI: 10.1007/S00213-008-1233-5  0.96
2009 Lang L, Ma Y, Kim BM, Jagoda EM, Rice KC, Szajek LP, Contoreggi C, Gold PW, Chrousos GP, Eckelman WC, Kiesewettera DO. [76Br]BMK-I-152, a non-peptide analogue for PET imaging of corticotropin-releasing hormone type 1 receptor (CRHR1) Journal of Labelled Compounds and Radiopharmaceuticals. 52: 394-400. DOI: 10.1002/Jlcr.1616  0.96
2009 De Bruyne S, Boos TL, Wyffels L, Goeman JL, Rice KC, De Vos F. Synthesis, radiosynthesis and in vivo evaluation of [123I]-4-(2- (bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine as a selective tracer for imaging the dopamine transporter Journal of Labelled Compounds and Radiopharmaceuticals. 52: 304-311. DOI: 10.1002/jlcr.1603  0.96
2008 Kurimura M, Liu H, Sulima A, Hashimoto A, Przybyl AK, Ohshima E, Kodato S, Deschamps JR, Dersch CM, Rothman RB, Yong SL, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 37.1 Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analogues of the ortho- and para-d-isomers Journal of Medicinal Chemistry. 51: 7866-7881. PMID 19053757 DOI: 10.1021/Jm800913D  0.96
2008 Zezula J, Singer L, Przybył AK, Hashimoto A, Dersch CM, Rothman RB, Deschamps J, Lee YS, Jacobson AE, Rice KC. Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans. Organic & Biomolecular Chemistry. 6: 2868-83. PMID 18688479 DOI: 10.1039/B803433H  0.96
2008 Hutchinson MR, Zhang Y, Brown K, Coats BD, Shridhar M, Sholar PW, Patel SJ, Crysdale NY, Harrison JA, Maier SF, Rice KC, Watkins LR. Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). The European Journal of Neuroscience. 28: 20-9. PMID 18662331 DOI: 10.1111/J.1460-9568.2008.06321.X  0.96
2008 Roma PG, Rinker JA, Serafine KM, Chen SA, Barr CS, Cheng K, Rice KC, Riley AL. Genetic and early environmental contributions to alcohol's aversive and physiological effects. Pharmacology, Biochemistry, and Behavior. 91: 134-9. PMID 18639579 DOI: 10.1016/J.Pbb.2008.06.022  0.96
2008 Do Carmo GP, Polt R, Bilsky EJ, Rice KC, Negus SS. Behavioral pharmacology of the mu/delta opioid glycopeptide MMP2200 in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 326: 939-48. PMID 18511649 DOI: 10.1124/Jpet.108.138180  0.96
2008 Rutherford JM, Wang J, Xu H, Dersch CM, Partilla JS, Rice KC, Rothman RB. Evidence for a mu-delta opioid receptor complex in CHO cells co-expressing mu and delta opioid peptide receptors. Peptides. 29: 1424-31. PMID 18472184 DOI: 10.1016/J.Peptides.2008.03.019  0.96
2008 Horn TL, Harder JB, Johnson WD, Curry PT, Parchment RE, Morrissey RL, Mellick PW, Calis KA, Gold PW, Rice KC, Contoreggi C, Charney DS, Cizza G, Glaze ER, Tomaszewski JE, et al. Integration of in vivo and in vitro approaches to characterize the toxicity of Antalarmin, a corticotropin-releasing hormone receptor antagonist Toxicology. 248: 8-17. PMID 18423834 DOI: 10.1016/J.Tox.2008.03.002  0.96
2008 Hsin LW, Chang LT, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Design and synthesis of 2- and 3-substituted-3-phenylpropyl analogs of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: Role of amino, fluoro, hydroxyl, methoxyl, methyl, methylene, and oxo substituents on affinity for the dopamine and serotonin transporters Journal of Medicinal Chemistry. 51: 2795-2806. PMID 18393401 DOI: 10.1021/Jm701270N  0.96
2008 Yang X, Wang S, Rice KC, Munro CA, Wand GS. Restraint stress and ethanol consumption in two mouse strains. Alcoholism, Clinical and Experimental Research. 32: 840-52. PMID 18336636 DOI: 10.1111/J.1530-0277.2008.00632.X  0.96
2008 Pascoe JE, Williams KL, Mukhopadhyay P, Rice KC, Woods JH, Ko MC. Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic-pituitary-adrenal axis in monkeys. Psychoneuroendocrinology. 33: 478-86. PMID 18325678 DOI: 10.1016/J.Psyneuen.2008.01.006  0.96
2008 Li JX, Rice KC, France CP. Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 324: 827-33. PMID 17993605 DOI: 10.1124/Jpet.107.130625  0.96
2008 Jutkiewicz EM, Baladi MG, Folk JE, Rice KC, Woods JH. The delta-opioid receptor agonist SNC80 [(+)-4-[alpha(R)-alpha-[(2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl]-(3-methoxybenzyl)-N,N-diethylbenzamide] synergistically enhances the locomotor-activating effects of some psychomotor stimulants, but not direct dopamine agonists, in rats. The Journal of Pharmacology and Experimental Therapeutics. 324: 714-24. PMID 17986650 DOI: 10.1124/Jpet.107.123844  0.96
2008 Reissig CJ, Eckler JR, Rabin RA, Rice KC, Winter JC. The stimulus effects of 8-OH-DPAT: evidence for a 5-HT2A receptor-mediated component. Pharmacology, Biochemistry, and Behavior. 88: 312-7. PMID 17936346 DOI: 10.1016/J.Pbb.2007.09.011  0.96
2008 Fantegrossi WE, Reissig CJ, Katz EB, Yarosh HL, Rice KC, Winter JC. Hallucinogen-like effects of N,N-dipropyltryptamine (DPT): Possible mediation by serotonin 5-HT1A and 5-HT2A receptors in rodents Pharmacology Biochemistry and Behavior. 88: 358-365. PMID 17905422 DOI: 10.1016/J.Pbb.2007.09.007  0.96
2008 Cheng K, Saha B, Mahadevan A, Razdan RK, Kunos G, Jacobson AE, Rice KC. Synthesis of 2-(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenamidoethyl-d 4 dihydrogen phosphate, tetra-deuterated pAEA Journal of Labelled Compounds and Radiopharmaceuticals. 51: 389-390. DOI: 10.1002/Jlcr.1540  0.96
2007 Hutchinson MR, Bland ST, Johnson KW, Rice KC, Maier SF, Watkins LR. Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward. Thescientificworldjournal. 7: 98-111. PMID 17982582 DOI: 10.1100/Tsw.2007.230  0.96
2007 Zhao Y, Valdez GR, Fekete EM, Rivier JE, Vale WW, Rice KC, Weiss F, Zorrilla EP. Subtype-selective corticotropin-releasing factor receptor agonists exert contrasting, but not opposite, effects on anxiety-related behavior in rats. The Journal of Pharmacology and Experimental Therapeutics. 323: 846-54. PMID 17855476 DOI: 10.1124/Jpet.107.123208  0.96
2007 Marinelli PW, Funk D, Juzytsch W, Harding S, Rice KC, Shaham Y, Lê AD. The CRF1 receptor antagonist antalarmin attenuates yohimbine-induced increases in operant alcohol self-administration and reinstatement of alcohol seeking in rats. Psychopharmacology. 195: 345-55. PMID 17705061 DOI: 10.1007/S00213-007-0905-X  0.96
2007 Winter JC, Rice KC, Amorosi DJ, Rabin RA. Psilocybin-induced stimulus control in the rat Pharmacology Biochemistry and Behavior. 87: 472-480. PMID 17688928 DOI: 10.1016/J.Pbb.2007.06.003  0.96
2007 Hiebel AC, Lee YS, Bilsky E, Giuvelis D, Deschamps JR, Parrish DA, Aceto MD, May EL, Harris LS, Coop A, Dersch CM, Partilla JS, Rothman RB, Cheng K, Jacobson AE, ... Rice KC, et al. Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure-activity relationships of a potent mu-agonist delta-antagonist and an exceedingly potent antinociceptive in the enantiomeric C9-substituted 5-(3-hydroxyphenyl)-N-phenylethylmorphan series. Journal of Medicinal Chemistry. 50: 3765-76. PMID 17625813 DOI: 10.1021/Jm061325E  0.96
2007 Li JX, Rice KC, France CP. Behavioral effects of dipropyltryptamine in rats: evidence for 5-HT1A and 5-HT2A agonist activity. Behavioural Pharmacology. 18: 283-8. PMID 17551320 DOI: 10.1097/Fbp.0B013E3281F19Ca0  0.96
2007 Kino T, Rice KC, Chrousos GP. The PPARδ agonist GW501516 suppresses interleukin-6-mediated hepatocyte acute phase reaction via STAT3 inhibition European Journal of Clinical Investigation. 37: 425-433. PMID 17461989 DOI: 10.1111/J.1365-2362.2007.01796.X  0.96
2007 Kino T, Boos TL, Sulima A, Siegel EM, Gold PW, Rice KC, Chrousos GP. 3-O-Formyl-20R,21-epoxyresibufogenin suppresses IL-6-type cytokine actions by targeting the glycoprotein 130 subunit: potential clinical implications. The Journal of Allergy and Clinical Immunology. 120: 437-44. PMID 17451794 DOI: 10.1016/J.Jaci.2007.03.018  0.88
2007 Wang B, You ZB, Rice KC, Wise RA. Stress-induced relapse to cocaine seeking: roles for the CRF(2) receptor and CRF-binding protein in the ventral tegmental area of the rat. Psychopharmacology. 193: 283-94. PMID 17437087 DOI: 10.1007/S00213-007-0782-3  0.96
2007 Cheng K, Kim IJ, Lee MJ, Adah SA, Raymond TJ, Bilsky EJ, Aceto MD, May EL, Harris LS, Coop A, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Opioid ligands with mixed properties from substituted enantiomeric N-phenethyl-5-phenylmorphans. Synthesis of a micro-agonist delta-antagonist and delta-inverse agonists. Organic & Biomolecular Chemistry. 5: 1177-90. PMID 17406716 DOI: 10.1039/B618875C  0.96
2007 Collins GT, Newman AH, Grundt P, Rice KC, Husbands SM, Chauvignac C, Chen J, Wang S, Woods JH. Yawning and hypothermia in rats: effects of dopamine D3 and D2 agonists and antagonists. Psychopharmacology. 193: 159-70. PMID 17393143 DOI: 10.1007/S00213-007-0766-3  0.96
2007 Gilbert KM, Boos TL, Dersch CM, Greiner E, Jacobson AE, Lewis D, Matecka D, Prisinzano TE, Zhang Y, Rothman RB, Rice KC, Venanzi CA. DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods. Bioorganic & Medicinal Chemistry. 15: 1146-59. PMID 17127069 DOI: 10.1016/J.Bmc.2006.09.070  0.96
2007 Funk CK, Zorrilla EP, Lee MJ, Rice KC, Koob GF. Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats. Biological Psychiatry. 61: 78-86. PMID 16876134 DOI: 10.1016/J.Biopsych.2006.03.063  0.96
2007 Zezula J, Jacobson AE, Rice KC. A novel divergent synthesis of ortho-hydroxy-E and -F oxide-bridged 5-phenylmorphans Heterocycles. 71: 881-889. DOI: 10.3987/Com-07-11000  0.6
2007 Zezula J, Rice KC, Hudlicky T. Design for morphine alkaloids by intramolecular Heck strategy: Chemoenzymatic synthesis of 10-hydroxy-14-epi-dihydrocodeinone via C-D-B ring construction Synlett. 2863-2867. DOI: 10.1055/S-2007-990832  0.96
2007 Sulima A, Folk J, Jacobson AE, Rice KC. A new approach to the synthesis of the nonpeptide NOP receptor antagonist J-113397 Synthesis. 1547-1553. DOI: 10.1055/S-2007-966037  0.96
2006 Mello NK, Negus SS, Rice KC, Mendelson JH. Effects of the CRF1 antagonist antalarmin on cocaine self-administration and discrimination in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 85: 744-51. PMID 17182090 DOI: 10.1016/J.Pbb.2006.11.008  0.96
2006 Zoumakis E, Rice KC, Gold PW, Chrousos GP. Potential uses of corticotropin-releasing hormone antagonists Annals of the New York Academy of Sciences. 1083: 239-251. PMID 17148743 DOI: 10.1196/Annals.1367.021  0.96
2006 Danielsson I, Gasior M, Stevenson GW, Folk JE, Rice KC, Negus SS. Electroencephalographic and convulsant effects of the delta opioid agonist SNC80 in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 85: 428-34. PMID 17112570 DOI: 10.1016/J.Pbb.2006.09.012  0.96
2006 Sabino V, Cottone P, Koob GF, Steardo L, Lee MJ, Rice KC, Zorrilla EP. Dissociation between opioid and CRF1 antagonist sensitive drinking in Sardinian alcohol-preferring rats. Psychopharmacology. 189: 175-86. PMID 17047935 DOI: 10.1007/S00213-006-0546-5  0.96
2006 Grakalic I, Schindler CW, Baumann MH, Rice KC, Riley AL. Effects of stress modulation on morphine-induced conditioned place preferences and plasma corticosterone levels in Fischer, Lewis, and Sprague-Dawley rat strains. Psychopharmacology. 189: 277-86. PMID 17016707 DOI: 10.1007/s00213-006-0562-5  0.96
2006 Do Carmo GP, Mello NK, Rice KC, Folk JE, Negus SS. Effects of the selective delta opioid agonist SNC80 on cocaine- and food-maintained responding in rhesus monkeys. European Journal of Pharmacology. 547: 92-100. PMID 16934797 DOI: 10.1016/J.Ejphar.2006.06.075  0.96
2006 Fox MA, Stevenson GW, Rice KC, Riley AL. Naloxone, not proglumide or MK-801, alters effects of morphine preexposure on morphine-induced taste aversions. Pharmacology, Biochemistry, and Behavior. 84: 169-77. PMID 16777201 DOI: 10.1016/J.Pbb.2006.05.003  0.96
2006 Wood SK, Verhoeven RE, Savit AZ, Rice KC, Fischbach PS, Woods JH. Facilitation of cardiac vagal activity by CRF-R1 antagonists during swim stress in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2580-90. PMID 16710322 DOI: 10.1038/Sj.Npp.1301085  0.96
2006 Boos TL, Greiner E, Calhoun WJ, Prisinzano TE, Nightingale B, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Structure-activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter. Bioorganic & Medicinal Chemistry. 14: 3967-73. PMID 16563775 DOI: 10.1016/J.Bmc.2006.01.065  0.96
2006 Jutkiewicz EM, Baladi MG, Folk JE, Rice KC, Woods JH. The convulsive and electroencephalographic changes produced by nonpeptidic delta-opioid agonists in rats: comparison with pentylenetetrazol. The Journal of Pharmacology and Experimental Therapeutics. 317: 1337-48. PMID 16537798 DOI: 10.1124/Jpet.105.095810  0.96
2006 Zhang H, Torregrossa MM, Jutkiewicz EM, Shi YG, Rice KC, Woods JH, Watson SJ, Ko MC. Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects. The European Journal of Neuroscience. 23: 984-94. PMID 16519663 DOI: 10.1111/J.1460-9568.2006.04621.X  0.96
2006 Greiner E, Boos TL, Prisinzano TE, De Martino MG, Zeglis B, Dersch CM, Marcus J, Partilla JS, Rothman RB, Jacobson AE, Rice KC. Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity. Journal of Medicinal Chemistry. 49: 1766-72. PMID 16509591 DOI: 10.1021/Jm050766F  0.96
2006 Fantegrossi WE, Harrington AW, Kiessel CL, Eckler JR, Rabin RA, Winter JC, Coop A, Rice KC, Woods JH. Hallucinogen-like actions of 5-methoxy-N,N-diisopropyltryptamine in mice and rats. Pharmacology, Biochemistry, and Behavior. 83: 122-9. PMID 16460788 DOI: 10.1016/J.Pbb.2005.12.015  0.96
2006 Jutkiewicz EM, Torregrossa MM, Sobczyk-Kojiro K, Mosberg HI, Folk JE, Rice KC, Watson SJ, Woods JH. Behavioral and neurobiological effects of the enkephalinase inhibitor RB101 relative to its antidepressant effects. European Journal of Pharmacology. 531: 151-9. PMID 16442521 DOI: 10.1016/J.Ejphar.2005.12.002  0.96
2006 Taylor JL, Bishop C, Ullrich T, Rice KC, Walker PD. Serotonin 2A receptor antagonist treatment reduces dopamine D1 receptor-mediated rotational behavior but not L-DOPA-induced abnormal involuntary movements in the unilateral dopamine-depleted rat. Neuropharmacology. 50: 761-8. PMID 16434065 DOI: 10.1016/J.Neuropharm.2005.12.004  0.96
2006 Gardell LR, King T, Ossipov MH, Rice KC, Lai J, Vanderah TW, Porreca F. Opioid receptor-mediated hyperalgesia and antinociceptive tolerance induced by sustained opiate delivery. Neuroscience Letters. 396: 44-9. PMID 16343768 DOI: 10.1016/J.Neulet.2005.11.009  0.96
2006 Ghitza UE, Gray SM, Epstein DH, Rice KC, Shaham Y. The anxiogenic drug yohimbine reinstates palatable food seeking in a rat relapse model: a role of CRF1 receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2188-96. PMID 16341025 DOI: 10.1038/Sj.Npp.1300964  0.96
2006 Hiebel AC, Partilla JS, Rothman RB, Jacobson AE, Rice KC. Synthesis of [3H]-labelled 4-[ethyl[2,5,6-trimethyl-7-(2,4,6- trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3-[3H]-butan-1- ol: A high affinity radioligand for the corticotropin-releasing hormone type 1 receptor Journal of Labelled Compounds and Radiopharmaceuticals. 49: 635-640. DOI: 10.1002/Jlcr.1082  0.96
2006 Zezula J, Wang HYJ, Woods AS, Wise RA, Jacobson AE, Rice KC. The high specific activity tritium labeling of the ganglion-blocking nicotinic antagonist chlorisondamine Journal of Labelled Compounds and Radiopharmaceuticals. 49: 471-478. DOI: 10.1002/Jlcr.1069  0.96
2005 Freeman KB, Rice KC, Riley AL. Assessment of monoamine transporter inhibition in the mediation of cocaine-induced conditioned taste aversion. Pharmacology, Biochemistry, and Behavior. 82: 583-9. PMID 16337262 DOI: 10.1016/J.Pbb.2005.10.014  0.96
2005 Torregrossa MM, Folk JE, Rice KC, Watson SJ, Woods JH. Chronic administration of the delta opioid receptor agonist (+)BW373U86 and antidepressants on behavior in the forced swim test and BDNF mRNA expression in rats. Psychopharmacology. 183: 31-40. PMID 16220339 DOI: 10.1007/S00213-005-0113-5  0.96
2005 Jutkiewicz EM, Rice KC, Traynor JR, Woods JH. Separation of the convulsions and antidepressant-like effects produced by the delta-opioid agonist SNC80 in rats. Psychopharmacology. 182: 588-96. PMID 16163520 DOI: 10.1007/S00213-005-0138-9  0.96
2005 Jutkiewicz EM, Kaminsky ST, Rice KC, Traynor JR, Woods JH. Differential behavioral tolerance to the delta-opioid agonist SNC80 ([(+)-4-[(alphaR)-alpha-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in Sprague-Dawley rats. The Journal of Pharmacology and Experimental Therapeutics. 315: 414-22. PMID 16014751 DOI: 10.1124/Jpet.105.088831  0.96
2005 Sulima A, Prisinzano TE, Spande T, Deschamps JR, Whittaker N, Hochberg Z, Jacobson AE, Rice KC. A concise method for the preparation of deuterium-labeled cortisone: synthesis of [6,7-2H]cortisone. Steroids. 70: 763-9. PMID 16005918 DOI: 10.1016/J.Steroids.2005.04.006  0.96
2005 Winter JC, Kieres AK, Zimmerman MD, Reissig CJ, Eckler JR, Ullrich T, Rice KC, Rabin RA, Richards JB. The stimulus properties of LSD in C57BL/6 mice. Pharmacology, Biochemistry, and Behavior. 81: 830-7. PMID 16005500 DOI: 10.1016/J.Pbb.2005.05.014  0.96
2005 Fantegrossi WE, Harrington AW, Eckler JR, Arshad S, Rabin RA, Winter JC, Coop A, Rice KC, Woods JH. Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats. Psychopharmacology. 181: 496-503. PMID 15983786 DOI: 10.1007/S00213-005-0009-4  0.96
2005 Winter JC, Eckler JR, Rice KC, Rabin RA. Serotonergic/glutamatergic interactions: potentiation of phencyclidine-induced stimulus control by citalopram. Pharmacology, Biochemistry, and Behavior. 81: 694-700. PMID 15970314 DOI: 10.1016/J.Pbb.2005.03.022  0.96
2005 Wu H, Thatcher LN, Bernard D, Parrish DA, Deschamps JR, Rice KC, MacKerell AD, Coop A. Position of coordination of the lithium ion determines the regioselectivity of demethylations of 3,4-dimethoxymorphinans with L-selectride. Organic Letters. 7: 2531-4. PMID 15957883 DOI: 10.1021/Ol050433C  0.96
2005 Caballero-Hernández D, Weber RJ, Hicks ME, Tamez-Guerra R, Rodríguez-Padilla C, Tamez-Guerra P, Rice KC, Ananthan S, Gomez-Flores R. Potentiation of rat lymphocyte proliferation by novel non-peptidic synthetic opioids. International Immunopharmacology. 5: 1271-8. PMID 15914331 DOI: 10.1016/J.Intimp.2005.03.009  0.96
2005 Pick CG, Chernes Y, Rigai T, Rice KC, Schreiber S. The antinociceptive effect of zolpidem and zopiclone in mice Pharmacology Biochemistry and Behavior. 81: 417-423. PMID 15913749 DOI: 10.1016/J.Pbb.2005.02.013  0.96
2005 Nightingale B, Dersch CM, Boos TL, Greiner E, Calhoun WJ, Jacobson AE, Rice KC, Rothman RB. Studies of the biogenic amine transporters. XI. Identification of a 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR12909) analog that allosterically modulates the serotonin transporter. The Journal of Pharmacology and Experimental Therapeutics. 314: 906-15. PMID 15860577 DOI: 10.1124/Jpet.105.084376  0.96
2005 Stoffel EC, Ulibarri CM, Folk JE, Rice KC, Craft RM. Gonadal hormone modulation of mu, kappa, and delta opioid antinociception in male and female rats. The Journal of Pain : Official Journal of the American Pain Society. 6: 261-74. PMID 15820914 DOI: 10.1016/J.Jpain.2004.12.006  0.96
2005 Stevenson GW, Folk JE, Rice KC, Negus SS. Interactions between delta and mu opioid agonists in assays of schedule-controlled responding, thermal nociception, drug self-administration, and drug versus food choice in rhesus monkeys: studies with SNC80 [(+)-4-[(alphaR)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide] and heroin. The Journal of Pharmacology and Experimental Therapeutics. 314: 221-31. PMID 15792997 DOI: 10.1124/Jpet.104.082685  0.96
2005 Herin DV, Liu S, Ullrich T, Rice KC, Cunningham KA. Role of the serotonin 5-HT2A receptor in the hyperlocomotive and hyperthermic effects of (+)-3,4-methylenedioxymethamphetamine. Psychopharmacology. 178: 505-13. PMID 15765263 DOI: 10.1007/S00213-004-2030-4  0.96
2005 Jutkiewicz EM, Wood SK, Houshyar H, Hsin LW, Rice KC, Woods JH. The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats. Psychopharmacology. 180: 215-23. PMID 15696320 DOI: 10.1007/S00213-005-2164-Z  0.96
2005 Jutkiewicz EM, Walker NP, Folk JE, Rice KC, Portoghese PS, Woods JH, Traynor JR. Comparison of peptidic and nonpeptidic delta-opioid agonists on guanosine 5'-O-(3-[35S]thio)triphosphate ([35S]GTPgammaS) binding in brain slices from Sprague-Dawley rats. The Journal of Pharmacology and Experimental Therapeutics. 312: 1314-20. PMID 15574687 DOI: 10.1124/Jpet.104.078741  0.96
2004 Contoreggi C, Rice KC, Chrousos G. Nonpeptide corticotropin-releasing hormone receptor type 1 antagonists and their applications in psychosomatic disorders Neuroendocrinology. 80: 111-123. PMID 15523186 DOI: 10.1159/000081785  0.96
2004 Hashimoto A, Przybyl AK, Linders JT, Kodato S, Tian X, Deschamps JR, George C, Flippen-Anderson JL, Jacobson AE, Rice KC. Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans. The Journal of Organic Chemistry. 69: 5322-7. PMID 15287777 DOI: 10.1021/Jo040159K  0.6
2004 Kim IJ, Dersch CM, Rothman RB, Jacobson AE, Rice KC. A critical structural determinant of opioid receptor interaction with phenolic 5-phenylmorphans. Bioorganic & Medicinal Chemistry. 12: 4543-4550. PMID 15265502 DOI: 10.1016/J.Bmc.2004.05.038  0.6
2004 Eckelman WC, Rice KC, Contoreggi C. New tools to monitor stress using non-invasive PET imaging Annals of the New York Academy of Sciences. 1018: 487-494. PMID 15240406 DOI: 10.1196/Annals.1296.060  0.96
2004 Yu H, Kim IJ, Folk JE, Tian X, Rothman RB, Baumann MH, Dersch CM, Flippen-Anderson JL, Parrish D, Jacobson AE, Rice KC. Synthesis and pharmacological evaluation of 3-(3,4-dichlorophenyl)-1-indanamine derivatives as nonselective ligands for biogenic amine transporters. Journal of Medicinal Chemistry. 47: 2624-34. PMID 15115403 DOI: 10.1021/Jm0305873  0.6
2004 Bishop C, Tessmer JL, Ullrich T, Rice KC, Walker PD. Serotonin 5-HT2A receptors underlie increased motor behaviors induced in dopamine-depleted rats by intrastriatal 5-HT2A/2C agonism. The Journal of Pharmacology and Experimental Therapeutics. 310: 687-94. PMID 15044557 DOI: 10.1124/Jpet.104.066365  0.96
2004 Broadbear JH, Winger G, Rivier JE, Rice KC, Woods JH. Corticotropin-releasing hormone antagonists, astressin B and antalarmin: differing profiles of activity in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1112-21. PMID 14997174 DOI: 10.1038/Sj.Npp.1300410  0.96
2004 Lindsey KP, Wilcox KM, Votaw JR, Goodman MM, Plisson C, Carroll FI, Rice KC, Howell LL. Effects of dopamine transporter inhibitors on cocaine self-administration in rhesus monkeys: relationship to transporter occupancy determined by positron emission tomography neuroimaging. The Journal of Pharmacology and Experimental Therapeutics. 309: 959-69. PMID 14982963 DOI: 10.1124/Jpet.103.060293  0.96
2004 Kodato S, Linders JT, Gu XH, Yamada K, Flippen-Anderson JL, Deschamps JR, Jacobson AE, Rice KC. Synthesis of rac-(1R,4aR,9aR)-2-methyl-1,3,4,9a-tetrahydro-2H-1,4a-propanobenzofuro[2,3-c]pyridin-6-ol. An unusual double rearrangement leading to the ortho- and para-f oxide-bridged phenylmorphan isomers. Organic & Biomolecular Chemistry. 2: 330-6. PMID 14747861 DOI: 10.1039/B312633C  0.6
2004 Fantegrossi WE, Kiessel CL, Leach PT, Van Martin C, Karabenick RL, Chen X, Ohizumi Y, Ullrich T, Rice KC, Woods JH. Nantenine: an antagonist of the behavioral and physiological effects of MDMA in mice. Psychopharmacology. 173: 270-7. PMID 14740148 DOI: 10.1007/S00213-003-1741-2  0.96
2004 Jutkiewicz EM, Eller EB, Folk JE, Rice KC, Traynor JR, Woods JH. Delta-opioid agonists: differential efficacy and potency of SNC80, its 3-OH (SNC86) and 3-desoxy (SNC162) derivatives in Sprague-Dawley rats. The Journal of Pharmacology and Experimental Therapeutics. 309: 173-81. PMID 14722329 DOI: 10.1124/Jpet.103.061242  0.96
2004 Greiner E, Folk JE, Jacobson AE, Rice KC. A novel and facile preparation of bremazocine enantiomers through optically pure N-norbremazocines Bioorganic and Medicinal Chemistry. 12: 233-238. PMID 14697788 DOI: 10.1016/J.Bmc.2003.10.029  0.96
2004 Torregrossa MM, Isgor C, Folk JE, Rice KC, Watson SJ, Woods JH. The delta-opioid receptor agonist (+)BW373U86 regulates BDNF mRNA expression in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 649-59. PMID 14647482 DOI: 10.1038/Sj.Npp.1300345  0.96
2004 Thompson CM, Wojno H, Greiner E, May EL, Rice KC, Selley DE. Activation of G-proteins by morphine and codeine congeners: insights to the relevance of O- and N-demethylated metabolites at mu- and delta-opioid receptors. The Journal of Pharmacology and Experimental Therapeutics. 308: 547-54. PMID 14600248 DOI: 10.1124/Jpet.103.058602  0.96
2004 Prisinzano T, Rice KC, Baumann MH, Rothman RB. Development of Neurochemical Normalization ("Agonist Substitution") Therapeutics for Stimulant Abuse: Focus on the Dopamine Uptake Inhibitor, GBR12909 Current Medicinal Chemistry - Central Nervous System Agents. 4: 47-59. DOI: 10.2174/1568015043477630  0.96
2004 Deschamps JR, Coop A, Parrish DA, Rice KC. 7β,14β-Epoxyhydrocodone-6,6-dimethoxy ketal: An unusual oxetane-containing opioid Acta Crystallographica Section E: Structure Reports Online. 60: o331-o333. DOI: 10.1107/S1600536804002077  0.96
2003 Jutkiewicz EM, Rice KC, Woods JH, Winsauer PJ. Effects of the delta-opioid receptor agonist SNC80 on learning relative to its antidepressant-like effects in rats. Behavioural Pharmacology. 14: 509-16. PMID 14557718 DOI: 10.1097/00008877-200311000-00003  0.96
2003 Stevenson GW, Folk JE, Linsenmayer DC, Rice KC, Negus SS. Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception. The Journal of Pharmacology and Experimental Therapeutics. 307: 1054-64. PMID 14557380 DOI: 10.1124/Jpet.103.056515  0.96
2003 Kim IJ, Ullrich T, Janetka JW, Furness MS, Jacobson AE, Rothman RB, Dersch CM, Flippen-Anderson JL, George C, Rice KC. Diaryldimethylpiperazine ligands with μ- and δ-opioid receptor affinity: Synthesis of (+)-4-[(αR)-α -(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide and (-)-4-[(αR)-α -(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide Bioorganic and Medicinal Chemistry. 11: 4761-4768. PMID 14556791 DOI: 10.1016/S0968-0896(03)00496-6  0.96
2003 Rothman RB, Jayanthi S, Wang X, Dersch CM, Cadet JL, Prisinzano T, Rice KC, Baumann MH. High-dose fenfluramine administration decreases serotonin transporter binding, but not serotonin transporter protein levels, in rat forebrain. Synapse (New York, N.Y.). 50: 233-9. PMID 14515341 DOI: 10.1002/Syn.10266  0.68
2003 Jagoda E, Contoreggi C, Lee MJ, Kao CH, Szajek LP, Listwak S, Gold P, Chrousos G, Greiner E, Kim BM, Jacobson AE, Rice KC, Eckelman W. Autoradiographic visualization of corticotropin releasing hormone type 1 receptors with a nonpeptide ligand: synthesis of [(76)Br]MJL-1-109-2. Journal of Medicinal Chemistry. 46: 3559-62. PMID 12904058 DOI: 10.1021/Jm034077K  0.6
2003 Janetka JW, Furness MS, Zhang X, Coop A, Folk JE, Mattson MV, Jacobson AE, Rice KC. Enantioconvergent synthesis of (-)-(2R,5S)-1-allyl-2,5-dimethylpiperazine, an intermediate to δ-opioid receptor ligands Journal of Organic Chemistry. 68: 3976-3980. PMID 12737580 DOI: 10.1021/Jo0300385  0.96
2003 Williams KL, Ko MC, Rice KC, Woods JH. Effect of opioid receptor antagonists on hypothalamic-pituitary-adrenal activity in rhesus monkeys. Psychoneuroendocrinology. 28: 513-28. PMID 12689609 DOI: 10.1016/S0306-4530(02)00037-9  0.96
2003 Greiner E, Prisinzano T, Johnson EM, Dersch CM, Marcus J, Partilla JS, Rothman RB, Jacobson AE, Rice KC. Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine. Journal of Medicinal Chemistry. 46: 1465-9. PMID 12672246 DOI: 10.1021/Jm020419V  0.96
2003 Varga EV, Rubenzik MK, Stropova D, Sugiyama M, Grife V, Hruby VJ, Rice KC, Roeske WR, Yamamura HI. Converging protein kinase pathways mediate adenylyl cyclase superactivation upon chronic delta-opioid agonist treatment. The Journal of Pharmacology and Experimental Therapeutics. 306: 109-15. PMID 12660310 DOI: 10.1124/Jpet.103.049643  0.96
2003 Przybyl AK, Flippen-Anderson JL, Jacobson AE, Rice KC. Practical and high-yield syntheses of dihydromorphine from tetrahydrothebaine and efficient syntheses of (8S)-8-bromomorphide. The Journal of Organic Chemistry. 68: 2010-3. PMID 12608825 DOI: 10.1021/Jo0206871  0.6
2003 Fantegrossi WE, Godlewski T, Karabenick RL, Stephens JM, Ullrich T, Rice KC, Woods JH. Pharmacological characterization of the effects of 3,4-methylenedioxymethamphetamine ("ecstasy") and its enantiomers on lethality, core temperature, and locomotor activity in singly housed and crowded mice. Psychopharmacology. 166: 202-11. PMID 12563544 DOI: 10.1007/S00213-002-1261-5  0.96
2003 Okura T, Varga EV, Hosohata Y, Navratilova E, Cowell SM, Rice K, Nagase H, Hruby VJ, Roeske WR, Yamamura HI. Agonist-specific down-regulation of the human delta-opioid receptor. European Journal of Pharmacology. 459: 9-16. PMID 12505529 DOI: 10.1016/S0014-2999(02)02823-6  0.96
2003 Tadic D, Linders JTM, Flippen-Anderson JL, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. Part 31: Synthesis of rac-(3R,6aS,11aS)-2-methyl-1,3,4,5,6,11a-hexahydro-2H-3,6a-methanobenzofuro[2,3-c]azocine-10-ol, and azocine-8-ol, the ortho-c and the para-c oxide-bridged phenylmorphan isomers Tetrahedron. 59: 4603-4614. DOI: 10.1016/S0040-4020(03)00659-8  0.6
2002 Broadbear JH, Winger G, Rice KC, Woods JH. Antalarmin, a putative CRH-RI antagonist, has transient reinforcing effects in rhesus monkeys. Psychopharmacology. 164: 268-76. PMID 12424550 DOI: 10.1007/S00213-002-1187-Y  0.96
2002 Negus SS, Bidlack JM, Mello NK, Furness MS, Rice KC, Brandt MR. Delta opioid antagonist effects of buprenorphine in rhesus monkeys. Behavioural Pharmacology. 13: 557-70. PMID 12409994 DOI: 10.1097/00008877-200211000-00005  0.96
2002 Broom DC, Jutkiewicz EM, Rice KC, Traynor JR, Woods JH. Behavioral effects of delta-opioid receptor agonists: potential antidepressants? Japanese Journal of Pharmacology. 90: 1-6. PMID 12396021 DOI: 10.1254/Jjp.90.1  0.96
2002 Broom DC, Nitsche JF, Pintar JE, Rice KC, Woods JH, Traynor JR. Comparison of receptor mechanisms and efficacy requirements for delta-agonist-induced convulsive activity and antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 303: 723-9. PMID 12388657 DOI: 10.1124/Jpet.102.036525  0.96
2002 Dykstra LA, Granger AL, Allen RM, Zhang X, Rice KC. Antinociceptive effects of the selective delta opioid agonist SNC80 alone and in combination with mu opioids in the squirrel monkey titration procedure. Psychopharmacology. 163: 420-9. PMID 12373443 DOI: 10.1007/s00213-002-1100-8  0.96
2002 Broom DC, Jutkiewicz EM, Folk JE, Traynor JR, Rice KC, Woods JH. Convulsant activity of a non-peptidic delta-opioid receptor agonist is not required for its antidepressant-like effects in Sprague-Dawley rats. Psychopharmacology. 164: 42-8. PMID 12373418 DOI: 10.1007/S00213-002-1179-Y  0.96
2002 Prisinzano T, Greiner E, Johnson EM, Dersch CM, Marcus J, Partilla JS, Rothman RB, Jacobson AE, Rice KC. Piperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909): high affinity ligands for the dopamine transporter. Journal of Medicinal Chemistry. 45: 4371-4. PMID 12213078 DOI: 10.1021/Jm020264R  0.96
2002 Roth BL, Baner K, Westkaemper R, Siebert D, Rice KC, Steinberg S, Ernsberger P, Rothman RB. Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist. Proceedings of the National Academy of Sciences of the United States of America. 99: 11934-9. PMID 12192085 DOI: 10.1073/Pnas.182234399  0.52
2002 Hashimoto A, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Probes for narcotic receptor mediated phenomena. Part 28: new opioid antagonists from enantiomeric analogues of 5-(3-hydroxyphenyl)-N-phenylethylmorphan. Bioorganic & Medicinal Chemistry. 10: 3319-29. PMID 12150879 DOI: 10.1016/S0968-0896(02)00219-5  0.6
2002 Baumann MH, Phillips JM, Ayestas MA, Ali SF, Rice KC, Rothman RB. Preclinical evaluation of GBR12909 decanoate as a long-acting medication for methamphetamine dependence. Annals of the New York Academy of Sciences. 965: 92-108. PMID 12105088 DOI: 10.1111/J.1749-6632.2002.Tb04154.X  0.52
2002 Gabry KE, Chrousos GP, Rice KC, Mostafa RM, Sternberg E, Negrao AB, Webster EL, McCann SM, Gold PW. Marked suppression of gastric ulcerogenesis and intestinal responses to stress by a novel class of drugs. Molecular Psychiatry. 7: 474-83, 433. PMID 12082565 DOI: 10.1038/Sj.Mp.4001031  0.96
2002 Fantegrossi WE, Ullrich T, Rice KC, Woods JH, Winger G. 3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement. Psychopharmacology. 161: 356-64. PMID 12073162 DOI: 10.1007/S00213-002-1021-6  0.96
2002 Broom DC, Jutkiewicz EM, Folk JE, Traynor JR, Rice KC, Woods JH. Nonpeptidic delta-opioid receptor agonists reduce immobility in the forced swim assay in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 744-55. PMID 12007745 DOI: 10.1016/S0893-133X(01)00413-4  0.96
2002 Hsin LW, Dersch CM, Baumann MH, Stafford D, Glowa JR, Rothman RB, Jacobson AE, Rice KC. Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: Chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy) ethyl]-4-(3-phenylpropyl)piperazine Journal of Medicinal Chemistry. 45: 1321-1329. PMID 11882001 DOI: 10.1021/Jm010430F  0.96
2002 Ko MC, Naughton NN, Traynor JR, Song MS, Woods JH, Rice KC, McKnight AT. Orphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptors. British Journal of Pharmacology. 135: 943-50. PMID 11861322 DOI: 10.1038/Sj.Bjp.0704535  0.96
2002 Stevenson GW, Cañadas F, Gomez-Serrano M, Ullrich T, Zhang X, Rice KC, Riley AL. Delta opioid discrimination learning in the rat: assessment with the selective delta agonist SNC80. Pharmacology, Biochemistry, and Behavior. 71: 283-92. PMID 11812534 DOI: 10.1016/S0091-3057(01)00658-X  0.96
2002 Hsin LW, Tian X, Webster EL, Coop A, Caldwell TM, Jacobson AE, Chrousos GP, Gold PW, Habib KE, Ayala A, Eckelman WC, Contoreggi C, Rice KC. CRHR1 Receptor binding and lipophilicity of pyrrolopyrimidines, potential nonpeptide corticotropin-releasing hormone type 1 receptor antagonists. Bioorganic & Medicinal Chemistry. 10: 175-83. PMID 11738619 DOI: 10.1016/S0968-0896(01)00261-9  0.96
2002 Yamada K, Flippen-Anderson JL, Jacobson AE, Rice KC. Probes for Narcotic Receptor Mediated Phenomena; 29: Synthesis of rac-(4R,6aR,11bR)-3-Methyl-... Synthesis. 2002: 2359-2364. DOI: 10.1055/S-2002-35237  0.6
2002 Rothman RB, Carroll FI, Morales M, Rowley DL, Rice KC, Dersch CM, Donovan DM. Studies of the biogenic amine transporters. 10. Characterization of a novel cocaine binding site in brain membranes prepared from dopamine transporter knockout miceThis article is a US Government work and, as such, is in the public domain in the United States of America. Synapse. 44: 94. DOI: 10.1002/Syn.10060.Abs  0.52
2002 Greiner E, Atkinson AJ, Ayala A, Chrousos GP, Contoreggi C, Eckelman WC, Gold PW, Habib KE, Jacobson AE, Whittaker N, Webster EL, Rice KC. Synthesis of doubly 13C-labelled antalarmin isotopomers for pharmacokinetic studies Journal of Labelled Compounds and Radiopharmaceuticals. 45: 637-645. DOI: 10.1002/Jlcr.576  0.96
2001 Zhang Y, Joseph DB, Bowen WD, Flippen-Anderson JL, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues. Journal of Medicinal Chemistry. 44: 3937-45. PMID 11689080 DOI: 10.1021/Jm0101592  0.96
2001 Ullrich T, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Derivatives of 17-(2-methylallyl)-substituted noroxymorphone: variation of the delta address and its effects on affinity and selectivity for the delta opioid receptor. Bioorganic & Medicinal Chemistry Letters. 11: 2883-2885. PMID 11597422 DOI: 10.1016/S0960-894X(01)00580-7  0.72
2001 Xu H, Lu YF, Rice KC, Ananthan S, Rothman RB. SoRI 9409, a non-peptide opioid mu receptor agonist/delta receptor antagonist, fails to stimulate [35S]-GTP-gamma-S binding at cloned opioid receptors. Brain Research Bulletin. 55: 507-11. PMID 11543951 DOI: 10.1016/S0361-9230(01)00550-0  0.96
2001 Gomez-Flores R, Rice KC, Zhang X, Weber RJ. Increased tumor necrosis factor-alpha and nitric oxide production by rat macrophages following in vitro stimulation and intravenous administration of the delta-opioid agonist SNC 80. Life Sciences. 68: 2675-84. PMID 11400911 DOI: 10.1016/S0024-3205(01)01082-7  0.56
2001 Hosohata Y, Varga EV, Stropova D, Li X, Knapp RJ, Hruby VJ, Rice KC, Nagase H, Roeske WR, Yamamura HI. Mutation W284L of the human delta opioid receptor reveals agonist specific receptor conformations for G protein activation. Life Sciences. 68: 2233-42. PMID 11358332 DOI: 10.1016/S0024-3205(01)01011-6  0.96
2001 McLamore S, Ullrich T, Rothman RB, Xu H, Dersch C, Coop A, Davis P, Porreca F, Jacobson AE, Rice KC. Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy. Journal of Medicinal Chemistry. 44: 1471-4. PMID 11311071 DOI: 10.1021/Jm000511W  0.96
2001 Xu H, Lu YF, Thomas JB, Carroll FI, Rice KC, Rothman RB. Opioid peptide receptor studies. 15. Relative efficacy of 4-[(N-allyl-3-methyl-4-piperidinyl)phenylamino]-N,N-diethylbenzamide and related compounds at the cloned human delta-opioid receptor. Synapse (New York, N.Y.). 40: 269-74. PMID 11309842 DOI: 10.1002/Syn.1049  0.52
2001 Tian X, Hsin LW, Webster EL, Contoreggi C, Chrousos GP, Gold PW, Habib K, Ayala A, Eckelman WC, Jacobson AE, Rice KC. The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type 1 Bioorganic and Medicinal Chemistry Letters. 11: 331-333. PMID 11212103 DOI: 10.1016/S0960-894X(00)00661-2  0.96
2001 Stafford D, LeSage MG, Rice KC, Glowa JR. A comparison of cocaine, GBR 12909, and phentermine self-administration by rhesus monkeys on a progressive-ratio schedule Drug and Alcohol Dependence. 62: 41-47. PMID 11173166 DOI: 10.1016/S0376-8716(00)00158-7  0.96
2001 Rothman RB, Baumann MH, Dersch CM, Romero DV, Rice KC, Carroll FI, Partilla JS. Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse (New York, N.Y.). 39: 32-41. PMID 11071707 DOI: 10.1002/1098-2396(20010101)39:1<32::Aid-Syn5>3.0.Co;2-3  0.52
2000 Stafford D, Rice KC, Lewis DB, Glowa JR. Response requirements and unit dose modify the effects of GBR 12909 on cocaine-maintained behavior Experimental and Clinical Psychopharmacology. 8: 539-548. PMID 11127425 DOI: 10.1037//1064-1297.8.4.539  0.96
2000 Gu XH, Yu H, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline. Journal of Medicinal Chemistry. 43: 4868-76. PMID 11123996 DOI: 10.1021/Jm000329V  0.6
2000 Zhang Y, Rothman RB, Dersch CM, Costa BRd, Jacobson aAE, Rice KC. Synthesis and transporter binding properties of bridged piperazine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909). Journal of Medicinal Chemistry. 43: 4840-4849. PMID 11123994 DOI: 10.1021/Jm000300R  0.68
2000 Rothman RB, Partilla JS, Dersch CM, Carroll FI, Rice KC, Baumann MH. Methamphetamine dependence: medication development efforts based on the dual deficit model of stimulant addiction. Annals of the New York Academy of Sciences. 914: 71-81. PMID 11085310 DOI: 10.1111/J.1749-6632.2000.Tb05185.X  0.52
2000 Coop A, Jacobson AE, Aceto MD, Harris LS, Traynor JR, Woods JH, Rice KC. N-Cyclohexylethyl-N-noroxymorphindole: a mu-opioid preferring analogue of naltrindole. Bioorganic & Medicinal Chemistry Letters. 10: 2449-51. PMID 11078198 DOI: 10.1016/S0960-894X(00)00479-0  0.96
2000 Ullrich T, Rice KC. A practical synthesis of the serotonin 5-HT(2a) receptor antagonist MDL 100907, its enantiomer and their 3-phenolic derivatives as precursors for [11C ]labeled PET ligands Bioorganic and Medicinal Chemistry. 8: 2427-2432. PMID 11058037 DOI: 10.1016/S0968-0896(00)00175-9  0.96
2000 Briscoe RJ, Cabrera CL, Baird TJ, Rice KC, Woods JH. Antalarmin blockade of corticotropin releasing hormone-induced hypertension in rats. Brain Research. 881: 204-7. PMID 11036160 DOI: 10.1016/S0006-8993(00)02742-6  0.96
2000 Stevenson GW, Cañadas F, Zhang X, Rice KC, Riley AL. Morphine discriminative control is mediated by the mu opioid receptor: assessment of delta opioid substitution and antagonism. Pharmacology, Biochemistry, and Behavior. 66: 851-6. PMID 10973525 DOI: 10.1016/S0091-3057(00)00280-X  0.96
2000 Hutchinson AC, Simpson GR, Randall JF, Zhang X, Calderon SN, Rice KC, Riley AL. Assessment of SNC 80 and naltrindole within a conditioned taste aversion design. Pharmacology, Biochemistry, and Behavior. 66: 779-87. PMID 10973516 DOI: 10.1016/S0091-3057(00)00278-1  0.96
2000 Furness MS, Zhang X, Coop A, Jacobson AE, Rothman RB, Dersch CM, Xu H, Porreca F, Rice KC. Probes for narcotic receptor-mediated phenomena. 27. Synthesis and pharmacological evaluation of selective delta-opioid receptor agonists from 4-[(alphaR)-alpha-(2S,5R)-4-substituted-2, 5-dimethyl-1-piperazinyl-3-methoxybenzyl]-N,N-diethylbenzamides and their enantiomers. Journal of Medicinal Chemistry. 43: 3193-6. PMID 10956228 DOI: 10.1021/Jm0001222  0.96
2000 Habib KE, Weld KP, Rice KC, Pushkas J, Champoux M, Listwak S, Webster EL, Atkinson AJ, Schulkin J, Contoreggi C, Chrousos GP, McCann SM, Suomi SJ, Higley JD, Gold PW. Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates. Proceedings of the National Academy of Sciences of the United States of America. 97: 6079-84. PMID 10823952 DOI: 10.1073/Pnas.97.11.6079  0.96
2000 Hsin LW, Webster EL, Chrousos GP, Gold PW, Eckelman WC, Contoreggi C, Rice KC. Synthesis and biological activity of fluoro-substituted pyrrolo[2,3-d]pyrimidines: The development of potential positron emission tomography imaging agents for the corticotropin-releasing hormone type 1 receptor Bioorganic and Medicinal Chemistry Letters. 10: 707-710. PMID 10782669 DOI: 10.1016/S0960-894X(00)00071-8  0.96
2000 Baumann MH, Ayestas MA, Dersch CM, Brockington A, Rice KC, Rothman RB. Effects of phentermine and fenfluramine on extracellular dopamine and serotonin in rat nucleus accumbens: therapeutic implications. Synapse. 36: 102-113. PMID 10767057 DOI: 10.1002/(Sici)1098-2396(200005)36:2<102::Aid-Syn3>3.0.Co;2-#  0.52
2000 Hosohata Y, Vanderah TW, Burkey TH, Ossipov MH, Kovelowski CJ, Sora I, Uhl GR, Zhang X, Rice KC, Roeske WR, Hruby VJ, Yamamura HI, Lai J, Porreca F. delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice. European Journal of Pharmacology. 388: 241-8. PMID 10675732 DOI: 10.1016/S0014-2999(99)00897-3  0.96
2000 Rothman RB, Partilla JS, Baumann MH, Dersch CM, Carroll FI, Rice KC. Neurochemical neutralization of methamphetamine with high-affinity nonselective inhibitors of biogenic amine transporters: a pharmacological strategy for treating stimulant abuse. Synapse (New York, N.Y.). 35: 222-7. PMID 10657029 DOI: 10.1002/(Sici)1098-2396(20000301)35:3<222::Aid-Syn7>3.0.Co;2-K  0.52
2000 Kirby LG, Rice KC, Valentino RJ. Effects of corticotropin-releasing factor on neuronal activity in the serotonergic dorsal raphe nucleus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 148-62. PMID 10649828 DOI: 10.1016/S0893-133X(99)00093-7  0.96
2000 Wong ML, Kling MA, Munson PJ, Listwak S, Licinio J, Prolo P, Karp B, McCutcheon IE, Geracioti TD, DeBellis MD, Rice KC, Goldstein DS, Veldhuis JD, Chrousos GP, Oldfield EH, et al. Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism and corticotropin-releasing hormone. Proceedings of the National Academy of Sciences of the United States of America. 97: 325-30. PMID 10618417 DOI: 10.1073/pnas.97.1.325  0.96
1999 Zhang X, Rice KC, Calderon SN, Kayakiri H, Smith L, Coop A, Jacobson AE, Rothman RB, Davis P, Dersch CM, Porreca F. Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic delta opioid receptor ligands. Journal of Medicinal Chemistry. 42: 5455-63. PMID 10639287 DOI: 10.1021/Jm9903895  0.96
1999 Coop A, Pinto J, Wang L, McCullough K, Rothman RB, Dersch C, Jacobson AE, Rice KC. Delta opioid binding selectivity of 3-ether analogs of naltrindole. Bioorganic & Medicinal Chemistry Letters. 9: 3435-8. PMID 10617086 DOI: 10.1016/S0960-894X(99)00622-8  0.96
1999 Lewis DB, Matecka D, Zhang Y, Hsin LW, Dersch CM, Stafford D, Glowa JR, Rothman RB, Rice KC. Oxygenated analogues of 1-[2-(diphenylmethoxy)ethyl]- and 1- [2- [bis (4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents Journal of Medicinal Chemistry. 42: 5029-5042. PMID 10585212 DOI: 10.1021/Jm990291Q  0.96
1999 Heyliger SO, Jackson C, Rice KC, Rothman RB. Opioid peptide receptor studies. 10. Nor-BNI differentially inhibits kappa receptor agonist-induced G-protein activation in the guinea pig caudate: Further evidence of kappa receptor heterogeneity Synapse. 34: 256-265. PMID 10529720 DOI: 10.1002/(Sici)1098-2396(19991215)34:4<256::Aid-Syn2>3.0.Co;2-6  0.96
1999 Romero DV, Partilla JS, Zheng Q, Heyliger SO, Ni Q, Rice KC, Lai J, Rothman RB. Opioid peptide receptor studies. 12. Buprenorphine is a potent and selective mu/kappa antagonist in the [35S]-GTP-gamma-S functional binding assay. Synapse. 34: 83-94. PMID 10502307 DOI: 10.1002/(Sici)1098-2396(199911)34:2<83::Aid-Syn1>3.0.Co;2-S  0.52
1999 Ananthan S, Kezar HS, Carter RL, Saini SK, Rice KC, Wells JL, Davis P, Xu H, Dersch CM, Bilsky EJ, Porreca F, Rothman RB. Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans. Journal of Medicinal Chemistry. 42: 3527-38. PMID 10479286 DOI: 10.1021/Jm990039I  0.96
1999 Villemagne VL, Wong DF, Yokoi F, Stephane M, Rice KC, Matecka D, Clough DJ, Dannals RF, Rothman RB. GBR12909 attenuates amphetamine-induced striatal dopamine release as measured by [(11)C]raclopride continuous infusion PET scans. Synapse (New York, N.Y.). 33: 268-73. PMID 10421707 DOI: 10.1002/(Sici)1098-2396(19990915)33:4<268::Aid-Syn3>3.0.Co;2-W  0.52
1999 Wong ML, Webster EL, Spokes H, Phu P, Ehrhart-Bornstein M, Bornstein S, Park CS, Rice KC, Chrousos GP, Licinio J, Gold PW. Chronic administration of the non-peptide CRH type 1 receptor antagonist antalarmin does not blunt hypothalamic-pituitary-adrenal axis responses to acute immobilization stress Life Sciences. 65. PMID 10421433 DOI: 10.1016/S0024-3205(99)00268-4  0.96
1999 Li JG, Chen C, Yin J, Rice K, Zhang Y, Matecka D, de Riel JK, DesJarlais RL, Liu-Chen LY. ASP147 in the third transmembrane helix of the rat mu opioid receptor forms ion-pairing with morphine and naltrexone. Life Sciences. 65: 175-85. PMID 10416823 DOI: 10.1016/S0024-3205(99)00234-9  0.96
1999 Coop A, Rothman RB, Dersch C, Partilla J, Porreca F, Davis P, Jacobson AE, Rice KC. delta Opioid affinity and selectivity of 4-hydroxy-3-methoxyindolomorphinan analogues related to naltrindole. Journal of Medicinal Chemistry. 42: 1673-9. PMID 10229636 DOI: 10.1021/Jm9807003  0.96
1999 Xu H, Lu Y, Partilla JS, Zheng Q, Wang J, Brine GA, Carroll FI, Rice KC, Chen K, Chi Z, Rothman RB. Opioid peptide receptor studies, 11: involvement of Tyr148, Trp318 and His319 of the rat mu-opioid receptor in binding of mu-selective ligands. Synapse. 32: 23-28. PMID 10188634 DOI: 10.1002/(Sici)1098-2396(199904)32:1<23::Aid-Syn3>3.0.Co;2-N  0.52
1999 Aceto MD, Harris LS, Abood ME, Rice KC. Stereoselective mu- and delta-opioid receptor-related antinociception and binding with (+)-thebaine. European Journal of Pharmacology. 365: 143-7. PMID 9988096 DOI: 10.1016/S0014-2999(98)00862-0  0.96
1999 Coop A, Rice KC. Direct and Simple Conversion of Codeine to Thebainone-A and Dihydrothebainone Heterocycles. 50: 39-42. DOI: 10.3987/Com-98-S(H)15  1
1999 Coop A, Rice KC. Studies into the direct oxidation of codeinone to 14-hydroxycodeinone Tetrahedron. 55: 11429-11436. DOI: 10.1016/S0040-4020(99)00665-1  0.96
1998 Kubota H, Rothman RB, Dersch C, McCullough K, Pinto J, Rice KC. Synthesis and biological activity of 3-substituted 3-desoxynaltrindole derivatives. Bioorganic & Medicinal Chemistry Letters. 8: 799-804. PMID 9871544 DOI: 10.1016/S0960-894X(98)00105-X  0.52
1998 Zhang Y, Williams W, Torrence-Campbell C, Bowen WD, Rice KC. Characterization of novel N,N'-disubstituted piperazines as sigma receptor ligands. Journal of Medicinal Chemistry. 41: 4950-7. PMID 9836612 DOI: 10.1021/Jm980143K  0.96
1998 Ni Q, Xu H, Partilla JS, Rice KC, Matecka D, Calderon SN, Porreca F, Lai J, Schmidhammer H, Krassnig R, Rothman RB. Opioid peptide receptor studies. 9. Identification of a novel non-mu- non-delta-like opioid peptide binding site in rat brain. Peptides. 19: 1079-90. PMID 9700759 DOI: 10.1016/S0196-9781(98)00046-1  0.96
1998 Schweri MM, De Costa BR, Rice KC. Fourphit, an acylating phencyclidine derivative, attenuates cocaine- induced hyperactivity in rats Pharmacology Biochemistry and Behavior. 60: 615-623. PMID 9678644 DOI: 10.1016/S0091-3057(98)00040-9  0.96
1998 Ananthan S, Johnson CA, Carter RL, Clayton SD, Rice KC, Xu H, Davis P, Porreca F, Rothman RB. Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety. Journal of Medicinal Chemistry. 41: 2872-81. PMID 9667975 DOI: 10.1021/Jm980083I  0.96
1998 Chan EC, Falconer J, Madsen G, Rice KC, Webster EL, Chrousos GP, Smith R. A corticotropin-releasing hormone type I receptor antagonist delays parturition in sheep. Endocrinology. 139: 3357-60. PMID 9645712 DOI: 10.1210/Endo.139.7.6189  0.96
1998 Bornstein SR, Webster EL, Torpy DJ, Richman SJ, Mitsiades N, Igel M, Lewis DB, Rice KC, Joost HG, Tsokos M, Chrousos GP. Chronic effects of a nonpeptide corticotropin-releasing hormone type I receptor antagonist on pituitary-adrenal function, body weight, and metabolic regulation Endocrinology. 139: 1546-1555. PMID 9528933 DOI: 10.1210/Endo.139.4.5938  0.96
1998 Rothman RB, Silverthorn ML, Glowa JR, Matecka D, Rice KC, Carroll FI, Partilla JS, Uhl GR, Vandenbergh DJ, Dersch CM. Studies of the biogenic amine transporters. VII. Characterization of a novel cocaine binding site identified with [125I]RTI-55 in membranes prepared from human, monkey and guinea pig caudate. Synapse (New York, N.Y.). 28: 322-38. PMID 9517841 DOI: 10.1002/(Sici)1098-2396(199804)28:4<322::Aid-Syn8>3.0.Co;2-B  0.96
1998 Xu H, Lu YF, Partilla JS, Pinto J, Calderon SN, Matecka D, Rice KC, Lai J, Porreca F, Ananthan S, Rothman RB. Opioid peptide receptor studies. 8. One of the mouse brain deltaNCX binding sites is similar to the cloned mouse opioid delta receptor: further evidence for heterogeneity of delta opioid receptors. Peptides. 19: 343-50. PMID 9493867 DOI: 10.1016/S0196-9781(97)00294-5  0.96
1998 Lu YF, Xu H, Liu-Chen LY, Chen C, Partilla JS, Brine GA, Carroll FI, Rice KC, Lai J, Porreca F, Sadee W, Rothman RB. Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor. Synapse (New York, N.Y.). 28: 117-24. PMID 9450512 DOI: 10.1002/(Sici)1098-2396(199802)28:2<117::Aid-Syn2>3.0.Co;2-E  0.96
1998 Coop A, Rice KC. A Novel Synthesis Of Thebaine From Codeine Heterocycles. 49: 43-47. DOI: 10.3987/Com-98-S8  1
1998 Coop A, Janetka JW, Lewis JW, Rice KC. L-Selectride as a general reagent for the O-demethylation and N-decarbomethoxylation of opium alkaloids and derivatives Journal of Organic Chemistry. 63: 4392-4396. DOI: 10.1021/Jo9801972  1
1998 Coop A, Rice KC. L-Selectride as a convenient reagent for the selective cleavage of carbamates Tetrahedron Letters. 39: 8933-8934. DOI: 10.1016/S0040-4039(98)02018-8  1
1998 Kubota H, Rice KC. Palladium-catalyzed cyanation of hindered, electron-rich aryl triflates by zinc cyanide Tetrahedron Letters. 39: 2907-2910. DOI: 10.1016/S0040-4039(98)00414-6  0.96
1997 Katsura Y, Zhang X, Homma K, Rice KC, Calderon SN, Rothman RB, Yamamura HI, Davis P, Flippen-Anderson JL, Xu H, Becketts K, Foltz EJ, Porreca F. Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists. Journal of Medicinal Chemistry. 40: 2936-47. PMID 9288176 DOI: 10.1021/Jm970106D  0.96
1997 Quock RM, Hosohata Y, Knapp RJ, Burkey TH, Hosohata K, Zhang X, Rice KC, Nagase H, Hruby VJ, Porreca F, Roeske WR, Yamamura HI. Relative efficacies of delta-opioid receptor agonists at the cloned human delta-opioid receptor. European Journal of Pharmacology. 326: 101-4. PMID 9178661 DOI: 10.1016/S0014-2999(97)83488-7  0.96
1997 Glowa JR, Rice KC, Matecka D, Rothman RB. Phentermine/fenfluramine decreases cocaine self-administration in rhesus monkeys Neuroreport. 8: 1347-1351. PMID 9172133 DOI: 10.1097/00001756-199704140-00006  0.96
1997 Calderon SN, Rice KC, Rothman RB, Porreca F, Flippen-Anderson JL, Kayakiri H, Xu H, Becketts K, Smith LE, Bilsky EJ, Davis P, Horvath R. Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands. Journal of Medicinal Chemistry. 40: 695-704. PMID 9057856 DOI: 10.1021/Jm960319N  0.56
1996 Coop A, Lewis JW, Rice KC. Direct and Simple O-Demethylation of Thebaine to Oripavine. The Journal of Organic Chemistry. 61: 6774. PMID 11667567 DOI: 10.1021/Jo961473K  0.96
1996 Glowa JR, Fantegrossi WE, Lewis DB, Matecka D, Rice KC, Rothman RB. Sustained decrease in cocaine-maintained responding in rhesus monkeys with 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-hydroxy-3- phenylpropyl)piperazinyl decanoate, a long-acting ester derivative of GBR 12909 Journal of Medicinal Chemistry. 39: 4689-4691. PMID 8941381 DOI: 10.1021/Jm960551T  0.96
1996 Webster EL, Lewis DB, Torpy DJ, Zachman EK, Rice KC, Chrousos GP. In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: Suppression of pituitary ACTH release and peripheral inflammation Endocrinology. 137: 5747-5750. PMID 8940412 DOI: 10.1210/Endo.137.12.8940412  0.96
1996 Staley JK, Ouyang Q, Pablo J, Hearn WL, Flynn DD, Rothman RB, Rice KC, Mash DC. Pharmacological screen for activities of 12-hydroxyibogamine: A primary metabolite of the indole alkaloid ibogaine Psychopharmacology. 127: 10-18. PMID 8880938 DOI: 10.1007/Bf02805969  0.96
1996 Elmer GI, Brockington A, Gorelick DA, Carrol FI, Rice KC, Matecka D, Goldberg SR, Rothman RB. Cocaine cross-sensitization to dopamine uptake inhibitors: Unique effects of GBR12909 Pharmacology Biochemistry and Behavior. 53: 911-918. PMID 8801597 DOI: 10.1016/0091-3057(95)02143-4  0.96
1996 Zhang Y, Williams W, Bowen WD, Rice KC. Synthesis and evaluation of aryl-substituted N-(arylethyl)-N-methyl-2-(1-pyrrolidinyl)ethylamines and corresponding arylacetamides for sigma receptor affinity. Journal of Medicinal Chemistry. 39: 3564-8. PMID 8784455 DOI: 10.1021/Jm9600813  0.96
1996 Matsumoto RR, Bowen WD, Walker JM, Patrick SL, Zambon AC, Vo VN, Truong DD, De Costa BR, Rice KC. Dissociation of the motor effects of (+)-pentazocine from binding to sigma 1 sites. European Journal of Pharmacology. 301: 31-40. PMID 8773444 DOI: 10.1016/0014-2999(96)00008-8  0.96
1996 Bertha CM, Ellis M, Flippen-Anderson JL, Porreca F, Rothman RB, Davis P, Xu H, Becketts K, Rice KC. Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity. Journal of Medicinal Chemistry. 39: 2081-6. PMID 8642567 DOI: 10.1021/Jm950695S  0.52
1996 Zhu J, Yin J, Law PY, Claude PA, Rice KC, Evans CJ, Chen C, Yu L, Liu-Chen LY. Irreversible binding of cis-(+)-3-methylfentanyl isothiocyanate to the delta opioid receptor and determination of its binding domain. The Journal of Biological Chemistry. 271: 1430-4. PMID 8576134 DOI: 10.1074/Jbc.271.3.1430  0.96
1996 Costa BRd, He X, Dominguez C, Williams W, Rice KC, Bowen WD. The role of novel ligands in the biological characterization of sigma receptors Pharmacochemistry Library. 24: 313-320. DOI: 10.1016/S0165-7208(96)80025-0  0.52
1996 Calderon SN, Bertha CM, Gutkind JS, Xu H, Partilla JS, Rothman RB, Rice KC. Probes for narcotic receptor mediated phenomena 22. (1) synthesis and characterization of optically pure [3H](+)-4-[(αR)-α-((2S, 5R)-4-propyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N, N-diethylbenzamide, [3H]SNC 121, a novel high affinity and select Journal of Labelled Compounds and Radiopharmaceuticals. 38: 847-850. DOI: 10.1002/(Sici)1099-1344(199609)38:9<847::Aid-Jlcr900>3.0.Co;2-N  0.56
1995 Cha XY, Xu H, Ni Q, Partilla JS, Rice KC, Matecka D, Calderon SN, Porreca F, Lai J, Rothman RB. Opioid peptide receptor studies. 4. Antisense oligodeoxynucleotide to the delta opioid receptor delineates opioid receptor subtypes Regulatory Peptides. 59: 247-253. PMID 8584761 DOI: 10.1016/0167-0115(95)00095-S  0.56
1995 Ni Q, Xu H, Partilla JS, Costa BRd, Rice KC, Kayakiri H, Rothman RB. Opioid peptide receptor studies. 3. Interaction of opioid peptides and other drugs with four subtypes of the κ2 receptor in guinea pig brain Peptides. 16: 1083-1095. PMID 8532593 DOI: 10.1016/0196-9781(95)00091-W  0.52
1995 Rothman RB, Xu H, Wang JB, Partilla JS, Kayakiri H, Rice KC, Uhl GR. Ligand selectivity of cloned human and rat opioid mu receptors. Synapse (New York, N.Y.). 21: 60-4. PMID 8525463 DOI: 10.1002/Syn.890210109  0.52
1995 Cha XY, Xu H, Rice KC, Porreca F, Lai J, Ananthan S, Rothman RB. Opioid peptide receptor studies. 1. Identification of a novel delta-opioid receptor binding site in rat brain membranes. Peptides. 16: 191-8. PMID 7784248 DOI: 10.1016/0196-9781(94)00182-0  0.96
1995 Bertha CM, Flippen-Anderson JL, Rothman RB, Porreca F, Davis P, Xu H, Becketts K, Cha XY, Rice KC. Probes for narcotic receptor-mediated phenomena. 20. Alteration of opioid receptor subtype selectivity of the 5-(3-hydroxyphenyl)morphans by application of the message-address concept: preparation of delta-opioid receptor ligands. Journal of Medicinal Chemistry. 38: 1523-37. PMID 7739011 DOI: 10.1021/Jm00009A013  0.52
1995 Xu H, Goodman CB, Partilla JS, Ni Q, Kayakiri H, Rice KC, Rothman RB. 6 beta-[125iodo]-3, 14-dihydroxy-17-methyl-4, 5 alpha-epoxymorphinan ([125I]IOXY-AGO): a potent and selective radioligand for opioid mu receptors. Synapse. 19: 105-111. PMID 7725239 DOI: 10.1002/Syn.890190206  0.52
1995 Bowen WD, Bertha CM, Vilner BJ, Rice KC. CB-64D and CB-184: ligands with high sigma 2 receptor affinity and subtype selectivity. European Journal of Pharmacology. 278: 257-60. PMID 7589164 DOI: 10.1016/0014-2999(95)00176-L  0.96
1995 Bertha CM, Vilner BJ, Mattson MV, Bowen WD, Becketts K, Xu H, Rothman RB, Flippen-Anderson JL, Rice KC. (E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype. Journal of Medicinal Chemistry. 38: 4776-85. PMID 7490727 DOI: 10.1021/Jm00024A005  0.96
1995 Glowa JR, Wojnicki FHE, Matecka D, Rice KC, Rothman RB. Effects of dopamine reuptake inhibitors on food- and cocaine-maintained responding: II. Comparisons with other drugs and repeated administrations Experimental and Clinical Psychopharmacology. 3: 232-239. DOI: 10.1037/1064-1297.3.3.232  0.96
1995 Glowa JR, Wojnicki FHE, Matecka D, Bacher JD, Mansbach RS, Balster RL, Rice KC. Effects of Dopamine Reuptake Inhibitors on Food-and Cocaine-Maintained Responding: I. Dependence on Unit Dose of Cocaine Experimental and Clinical Psychopharmacology. 3: 219-231. DOI: 10.1037/1064-1297.3.3.219  0.96
1994 Dersch CM, Akunne HC, Partilla JS, Char GU, de Costa BR, Rice KC, Carroll FI, Rothman RB. Studies of the biogenic amine transporters. 1. Dopamine reuptake blockers inhibit [3H]mazindol binding to the dopamine transporter by a competitive mechanism: preliminary evidence for different binding domains. Neurochemical Research. 19: 201-8. PMID 8183430 DOI: 10.1007/Bf00966817  0.52
1994 Petrov ES, Varlinskaya EI, Robinson SR, Smotherman WP, de Costa BR, Rice KC. Kappa opioid effects on fetal behavior: central administration of U50,488. Physiology & Behavior. 56: 175-82. PMID 8084898 DOI: 10.1016/0031-9384(94)90276-3  0.96
1994 Calderon SN, Rothman RB, Porreca F, Flippen-Anderson JL, McNutt RW, Xu H, Smith LE, Bilsky EJ, Davis P, Rice KC. Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(alpha R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3- methoxybenzyl]-N,N-diethylbenzamide (SNC 80): a highly selective, nonpeptide delta opioid receptor agonist. Journal of Medicinal Chemistry. 37: 2125-8. PMID 8035418 DOI: 10.1021/Jm00040A002  0.56
1994 Bertha CM, Mattson MV, Flippen-Anderson JL, Rothman RB, Xu H, Cha XY, Becketts K, Rice KC. A marked change of receptor affinity of the 2-methyl-5-(3-hydroxyphenyl)morphans upon attachment of an (E)-8-benzylidene moiety: synthesis and evaluation of a new class of sigma receptor ligands. Journal of Medicinal Chemistry. 37: 3163-70. PMID 7932540 DOI: 10.1021/Jm00045A022  0.52
1994 Smotherman WP, Robinson SR, Varlinskaya EI, Petrov ES, Orlowski M, de Costa BR, Rice KC. Central administration of the endopeptidase 24.15 inhibitor cFP-AAF-pAB suggests dynorphin as the endogenous ligand underlying behavioral effects of milk in the fetal rat. Pharmacology, Biochemistry, and Behavior. 47: 715-9. PMID 7911578 DOI: 10.1016/0091-3057(94)90178-3  0.96
1994 Ni Q, Xu H, Partilla JS, Costa BRd, Rice KC, Borsodi A, Hosztafi S, Rothman RB. Dihydrocodeinone-hydrazone, dihydrocodeinone-oxime, naloxone-3-ome-oxime, and clocinnamox fail to irreversibly inhibit opioid kappa receptor binding Neurochemical Research. 19: 1159-1163. PMID 7824069 DOI: 10.1007/Bf00965150  0.52
1994 Xu H, Partilla JS, Becketts KM, Kayakiri H, Rice KC, Rothman RB. [125I]IOXY-AGO: A high affinity, mu-selective agonist opioid receptor ligand Regulatory Peptides. 54: 331-332. DOI: 10.1016/0167-0115(94)90523-1  0.52
1994 Rothman RB, Xu H, Wang JB, Partilla JS, Kayakiri H, Rice KC, Uhl GR. The ligand-selectivity of cloned human and rat opiate mu receptors studied with [125I]IOXY-AGO Regulatory Peptides. 54: 249-250. DOI: 10.1016/0167-0115(94)90483-9  0.52
1994 Cha XY, Xu H, Calderon SN, Smith LE, Rice KC, Porreca F, Rothman RB. BW373U86, its enantiomers, and related compounds: Interactions of non-peptide delta agonists at multiple δcx binding sites in rat brain Regulatory Peptides. 54: 45-46. DOI: 10.1016/0167-0115(94)90381-6  0.56
1994 Silverthom ML, Dersch CM, Partilla JS, Carroll FI, Matecka DL, Rice KC, Rothman RB. [125]RTI-55, a high affinity cocaine analog, labels two binding sites in human caudate membranes possibly related to the 5-HT transporter Biological Psychiatry. 35: 644. DOI: 10.1016/0006-3223(94)90763-3  0.52
1994 He X, Matecka D, Lee KS, Gu ZQ, Rice KC, Wong G, Skolnick P, De Costa BR. Synthesis of [123I]tert-butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine 3-carboxylate, a potential SPECT imaging agent for diazepam-insensitive (DI) benzodiazepine receptors Journal of Labelled Compounds and Radiopharmaceuticals. 34: 27-32. DOI: 10.1002/Jlcr.2580340105  0.96
1993 Rothman RB, Lewis B, Dersch C, Xu H, Radesca L, Costa BRD, Rice KC, Kilburn RB, Akunne HC, Pert A. Identification of a GBR12935 homolog, LR1111, which is over 4,000-fold selective for the dopamine transporter, relative to serotonin and norepinephrine transporters. Synapse. 14: 34-39. PMID 8511716 DOI: 10.1002/Syn.890140106  0.52
1993 Rothman RB, Becketts KM, Radesca LR, Costa BRd, Rice KC, Carroll FI, Dersch CM. Studies of the biogenic amine transporters. II. A brief study on the use of [3H]DA-uptake-inhibition to transporter-binding-inhibition ratios for the in vitro evaluation of putative cocaine antagonists. Life Sciences. 53. PMID 8412496 DOI: 10.1016/0024-3205(93)90602-Y  0.52
1993 Rothman RB, Xu H, Char GU, Kim A, De Costa BR, Rice KC, Zimmerman DM. Phenylpiperidine opioid antagonists that promote weight loss in rats have high affinity for the kappa 2B (enkephalin-sensitive) binding site. Peptides. 14: 17-20. PMID 8382809 DOI: 10.1016/0196-9781(93)90005-2  0.96
1993 Linders JTM, Monn JA, Mattson MV, George C, Jacobson AE, Rice KC. Synthesis and binding properties of MK-801 isothiocyanates; (+)-3-isothiocyanato-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrochloride: a new, potent and selective electrophilic affinity ligand for the NMDA receptor-coupled phencyclidine binding site Journal of Medicinal Chemistry. 36: 2499-2507. PMID 8355251 DOI: 10.1021/Jm00069A008  0.6
1993 Xu H, Partilla JS, Costa BRd, Rice KC, Rothman RB. Differential binding of opioid peptides and other drugs to two subtypes of opioid binding sites in mouse brain: Further evidence for δ receptor heterogeneity Peptides. 14: 893-907. PMID 8284266 DOI: 10.1016/0196-9781(93)90064-N  0.52
1993 Ni Q, Xu H, Partilla JS, Costa BRD, Rice KC, Rothman RB. Selective labeling of κ2 opioid receptors in rat brain by [125I]IOXY: Interaction of opioid peptides and other drugs with multiple κ2a binding sites Peptides. 14: 1279-1293. PMID 8134311 DOI: 10.1016/0196-9781(93)90188-M  0.52
1992 Rothman RB, Grieg N, Kim A, Costa BRd, Rice KC, Carroll FI, Pert A. Cocaine and GBR12909 produce equivalent motoric responses at different occupancy of the dopamine transporter Pharmacology, Biochemistry and Behavior. 43: 1135-1142. PMID 1475296 DOI: 10.1016/0091-3057(92)90493-Y  0.52
1992 Akunne HC, Costa BRd, Jacobson AE, Rice KC, Rothman RB. [3H] cocaine labels a binding site associated with the serotonin transporter in guinea pig brain: allosteric modulation by paroxetine. Neurochemical Research. 17: 1275-1283. PMID 1461373 DOI: 10.1007/Bf00968412  0.6
1992 Reith ME, de Costa B, Rice KC, Jacobson AE. Evidence for mutually exclusive binding of cocaine, BTCP, GBR 12935, and dopamine to the dopamine transporter. European Journal of Pharmacology. 227: 417-25. PMID 1446712 DOI: 10.1016/0922-4106(92)90160-W  0.6
1992 France CP, Winger G, Seggel MR, Rice KC, Woods JH. Pharmacological profile of a potent, efficacious fentanyl derivative in rhesus monkeys. Psychopharmacology. 109: 291-8. PMID 1365629 DOI: 10.1007/Bf02245876  0.96
1992 Thurkauf A, Mattson MV, Richardson S, Mirsadeghi S, Ornstein PL, Harrison EA, Rice KC, Jacobson AE, Monn JA. Analogues of the dioxolanes dexoxadrol and etoxadrol as potential phencyclidine-like agents. Synthesis and structure-activity relationships. Journal of Medicinal Chemistry. 35: 1323-9. PMID 1349351 DOI: 10.1021/Jm00086A001  0.96
1992 Xu H, Partilla JS, Costa BRd, Rice KC, Rothman RB. Interaction of opioid peptides and other drugs with multiple δncx binding sites in rat brain: Further evidence for heterogeneity Peptides. 13: 1207-1213. PMID 1337380 DOI: 10.1016/0196-9781(92)90030-7  0.52
1992 Rothman RB, Mahboubi A, Bykov V, Kim C, Costa BRd, Jacobson AE, Rice KC. Probing the opioid receptor complex with (+)-trans-SUPERFIT. II. Evidence that μ ligands are noncompetitive inhibitors of the δcx opioid peptide binding site Peptides. 13: 1137-1143. PMID 1337378 DOI: 10.1016/0196-9781(92)90020-4  0.6
1992 Rothman RB, Bykov V, Xue BG, Xu H, De Costa BR, Jacobson AE, Rice KC, Kleinman JE, Brady LS. Interaction of opioid peptides and other drugs with multiple kappa receptors in rat and human brain. Evidence for species differences. Peptides. 13: 977-87. PMID 1336192 DOI: 10.1016/0196-9781(92)90059-C  0.96
1992 Theodore WH, Carson RE, Andreasen P, Zametkin A, Blasberg R, Leiderman DB, Rice K, Newman A, Channing M, Dunn B. PET imaging of opiate receptor binding in human epilepsy using [18F]cyclofoxy. Epilepsy Research. 13: 129-39. PMID 1334456 DOI: 10.1016/0920-1211(92)90068-5  0.32
1992 Rothman RB, Bykov V, Jacobson AE, Rice KC, Long JE, Bowen WD. A study of the effect of the irreversible delta receptor antagonist [D-Ala2,Leu5,Cys6]-enkephalin on delta cx and delta ncx opioid binding sites in vitro and in vivo. Peptides. 13: 691-4. PMID 1331996 DOI: 10.1016/0196-9781(92)90174-2  0.96
1992 de Costa BR, Iadarola MJ, Rothman RB, Berman KF, George C, Newman AH, Mahboubi A, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 18. Epimeric 6 alpha- and 6 beta-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5 alpha-epoxymorphinans as potential ligands for opioid receptor single photon emission computed tomography: synthesis, evaluation, and radiochemistry of [125I]-6 beta-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5 alpha-epoxymorphinan. Journal of Medicinal Chemistry. 35: 2826-35. PMID 1322988 DOI: 10.1021/Jm00093A016  0.96
1992 Jamieson GA, Agrawal AK, Greco NJ, Tenner TE, Jones GD, Rice KC, Jacobson AE, White JG, Tandon NN. Phencyclidine binds to blood platelets with high affinity and specifically inhibits their activation by adrenaline. The Biochemical Journal. 285: 35-9. PMID 1322125 DOI: 10.1042/Bj2850035  0.96
1992 Akunne HC, Johannessen JN, Costa BRd, Rice KC, Rothman RB. MPTP lesions of the nigrostriatal dopaminergic projection decrease [3H]1-[1-(2-thienyl)cyclohexyl]piperidine binding to PCP site 2: further evidence that PCP site 2 is associated with the biogenic amine reuptake complex. Neurochemical Research. 17: 261-264. PMID 1320214 DOI: 10.1007/Bf00966668  0.52
1992 Gu ZQ, De Costa BR, Wong G, Rice KC, Skolnick P. Synthesis of [3H]tert-butyl 8-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4-benzodiazepi ne 3-carboxylate, a selective, high affinity ligand for the diazepam insensitive (DI) subtype of the benzodiazepine receptor Journal of Labelled Compounds and Radiopharmaceuticals. 31: 1049-1055. DOI: 10.1002/Jlcr.2580311213  0.96
1991 Sawada Y, Kawai R, McManaway M, Otsuki H, Rice KC, Patlak CS, Blasberg RG. Kinetic analysis of transport and opioid receptor binding of [3H](-)-cyclofoxy in rat brain in vivo: implications for human studies. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 11: 183-203. PMID 1847702 DOI: 10.1038/Jcbfm.1991.51  0.32
1991 Rothman RB, Mele A, Reid AA, Akunne HC, Greig N, Thurkauf A, de Costa BR, Rice KC, Pert A. GBR12909 antagonizes the ability of cocaine to elevate extracellular levels of dopamine Pharmacology, Biochemistry and Behavior. 40: 387-397. PMID 1839568 DOI: 10.1016/0091-3057(91)90570-R  0.96
1991 Akunne HC, Reid AA, Thurkauf A, Jacobson AE, de Costa BR, Rice KC, Heyes MP, Rothman RB. [3H]1-[2-(2-thienyl)cyclohexyl]piperidine labels two high-affinity binding sites in human cortex: further evidence for phencyclidine binding sites associated with the biogenic amine reuptake complex. Synapse (New York, N.Y.). 8: 289-300. PMID 1833849 DOI: 10.1002/Syn.890080407  0.96
1991 Moody EJ, Lewin AH, de Costa BR, Rice KC, Skolnick P. Site-specific acylation of GABA-gated Cl- channels: effects on 36Cl- uptake. European Journal of Pharmacology. 206: 113-8. PMID 1712308 DOI: 10.1016/0922-4106(91)90019-E  0.48
1991 Xu H, Ni Q, Jacobson AE, Rice KC, Rothman RB. Preliminary ligand binding data for subtypes of the delta opioid receptor in rat brain membranes. Life Sciences. 49. PMID 1681403 DOI: 10.1016/0024-3205(91)90204-O  0.6
1991 Rothman RB, Bykov V, Mahboubi A, Long JB, Jiang Q, Porreca F, de Costa BR, Jacobson AE, Rice KC, Holaday JW. Interaction of beta-funaltrexamine with [3H]cycloFOXY binding in rat brain: further evidence that beta-FNA alkylates the opioid receptor complex. Synapse (New York, N.Y.). 8: 86-99. PMID 1652797 DOI: 10.1002/Syn.890080203  0.96
1991 Xu H, Kim CH, Zhu YC, Weber RJ, Jacobson AE, Rice KC, Rothman RB. (+)-cis-3-methylfentanyl and its analogs bind pseudoirreversibly to the mu opioid binding site: evidence for pseudoallosteric modulation. Neuropharmacology. 30: 455-62. PMID 1650928 DOI: 10.1016/0028-3908(91)90006-W  0.6
1991 Contreras PC, Ragan DM, Bremer ME, Lanthorn TH, Gray NM, Iyengar S, Jacobson AE, Rice KC, de Costa BR. Evaluation of U-50,488H analogs for neuroprotective activity in the gerbil. Brain Research. 546: 79-82. PMID 1649669 DOI: 10.1016/0006-8993(91)91161-S  0.96
1991 Witkin JM, Johnson RE, Jaffe JH, Goldberg SR, Grayson NA, Rice KC, Katz JL. The partial opioid agonist, buprenorphine, protects against lethal effects of cocaine. Drug and Alcohol Dependence. 27: 177-84. PMID 1647294 DOI: 10.1016/0376-8716(91)90037-Y  0.96
1991 Rothman RB, Long JB, Bykov V, Xu H, Jacobson AE, Rice KC, Holaday JW. Upregulation of the opioid receptor complex by the chronic administration of morphine: a biochemical marker related to the development of tolerance and dependence. Peptides. 12: 151-60. PMID 1646998 DOI: 10.1016/0196-9781(91)90182-O  0.96
1991 Carr DJJ, DeCosta BR, Jacobson AE, Rice KC, Blalock JE. Enantioselective kappa opioid binding sites on the macrophage cell line, P388d1. Life Sciences. 49: 45-51. PMID 1646923 DOI: 10.1016/0024-3205(91)90578-Y  0.6
1991 Kawai R, Carson RE, Dunn B, Newman AH, Rice KC, Blasberg RG. Regional brain measurement of Bmax and KD with the opiate antagonist cyclofoxy: equilibrium studies in the conscious rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 11: 529-44. PMID 1646826 DOI: 10.1038/Jcbfm.1991.102  0.64
1991 Rothman RB, Xu H, Seggel M, Jacobson AE, Rice KC, Brine GA, Carroll FI. RTI-4614-4: an analog of (+)-cis-3-methylfentanyl with a 27,000-fold binding selectivity for mu versus delta opioid binding sites. Life Sciences. 48. PMID 1646357 DOI: 10.1016/0024-3205(91)90346-D  0.6
1990 Thurkauf A, de Costa B, Mattson MV, France CP, Price MT, Olney JW, Woods JH, Jacobson AE, Rice KC. Synthesis, phencyclidine-like pharmacology, and antiischemic potential of meta-substituted 1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridines. Journal of Medicinal Chemistry. 33: 2211-5. PMID 2374147 DOI: 10.1021/Jm00170A027  0.96
1990 Thurkauf A, de Costa B, Yamaguchi S, Mattson MV, Jacobson AE, Rice KC, Rogawski MA. Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues. Journal of Medicinal Chemistry. 33: 1452-8. PMID 2329567 DOI: 10.1021/Jm00167A027  0.96
1990 Kawai R, Sawada Y, Channing M, Newman AH, Rice KC, Blasberg RG. BBB transport and rapid tissue binding of cyclofoxy: comparison of active and inactive enantiomers. The American Journal of Physiology. 259: H1278-87. PMID 2221131 DOI: 10.1152/Ajpheart.1990.259.4.H1278  0.64
1990 Band L, Xu H, Bykov V, Greig N, Chong-Ho Kim, Newman A, Jacobson AE, Rice KC, Rothman RB. The potent opioid agonist, (+)-cis-3-methylfentanyl binds pseudoirreversibly to the opioid receptor complex in vitro and in vivo: Evidence for a novel mechanism of action Life Sciences. 47: 2231-2240. PMID 2176265 DOI: 10.1016/0024-3205(90)90154-J  0.96
1990 Reid AA, Monn JA, Jacobson AE, Rice KC, Rothman RB. Pseudoallosteric modulation by (+)-MK801 of NMDA-coupled phencyclidine binding sites. Life Sciences. 47: PL77-82. PMID 2174483 DOI: 10.1016/0024-3205(90)90531-U  0.96
1990 Creveling CR, Bell ME, Burke TR, Chang E, Lewandowski-Lovenberg GA, Kim CH, Rice KC, Daly JW. Procaine isothiocyanate: an irreversible inhibitor of the specific binding of [3H]batrachotoxinin-A benzoate to sodium channels. Neurochemical Research. 15: 441-8. PMID 2167458 DOI: 10.1007/Bf00969931  0.96
1990 McCabe RT, Costa BRd, Miller RL, Havunjian RH, Rice KC, Skolnick P. Characterization of benzodiazepine receptors with fluorescent ligands. The Faseb Journal. 4: 2934-2940. PMID 2165950 DOI: 10.1096/Fasebj.4.11.2165950  0.48
1990 Rothman RB, Bykov V, de Costa BR, Jacobson AE, Rice KC, Brady LS. Interaction of endogenous opioid peptides and other drugs with four kappa opioid binding sites in guinea pig brain. Peptides. 11: 311-31. PMID 2162533 DOI: 10.1016/0196-9781(90)90088-M  0.96
1990 Carr DJJ, DeCosta BR, Kim CH, Jacobson AE, Bost KL, Rice KC, Blalock JE. Anti-opioid receptor antibody recognition of a binding site on brain and leukocyte opioid receptors Neuroendocrinology. 51: 552-560. PMID 2162012 DOI: 10.1159/000125390  0.96
1990 Rice KC, Bolger GT. Interactions between phencyclidine and nifedipine at 45Ca2+-uptake sites on mouse brain neurons Biochemical Pharmacology. 39: 1825-1827. PMID 2160822 DOI: 10.1016/0006-2952(90)90134-7  0.96
1990 Kiesewetter DO, Finn RD, Rice KC, Monn JA. Synthesis of 11C-labeled (±)-5-methyl-10, 11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine [(±)-[11C]MK801] International Journal of Radiation Applications and Instrumentation. Part. 41: 139-142. PMID 2158943 DOI: 10.1016/0883-2889(90)90098-2  0.96
1990 Monn JA, Thurkauf A, Mattson MV, Jacobson AE, Rice KC. Synthesis and structure-activity relationship of C5-substituted analogues of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine [(+-)-desmethyl-MK801]: ligands for the NMDA receptor-coupled phencyclidine binding site. Journal of Medicinal Chemistry. 33: 1069-1076. PMID 2155320 DOI: 10.1021/Jm00165A029  0.6
1990 Nabeshima T, Yoshida S, Morinaka H, Kameyama T, Thurkauf A, Rice KC, Jacobson AE, Monn JA, Cho AK. MK-801 ameliorates delayed amnesia, but potentiates acute amnesia induced by CO. Neuroscience Letters. 108: 321-327. PMID 2154727 DOI: 10.1016/0304-3940(90)90661-R  0.6
1990 Reid AA, Mattson MV, de Costa BR, Thurkauf A, Jacobson AE, Monn JA, Rice KC, Rothman RB. Specificity of phencyclidine-like drugs and benzomorphan opiates for two high affinity phencyclidine binding sites in guinea pig brain. Neuropharmacology. 29: 811-7. PMID 1963480 DOI: 10.1016/0028-3908(90)90154-J  0.96
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