Kenner C. Rice, Ph.D. - Publications

Affiliations: 
Drug Design and Synthesis Section, Chemical Biology Research Branch National Institute on Drug Abuse 
Area:
medicinal chemistry, drugs of abuse
Website:
http://irp.drugabuse.gov/Rice.html

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Pomrenze MB, Millan EZ, Hopf FW, Keiflin R, Maiya R, Blasio A, Dadgar J, Kharazia V, De Guglielmo G, Crawford E, Janak PH, George O, Rice KC, Messing RO. A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. Frontiers in Neuroscience. 9: 487. PMID 26733798 DOI: 10.3389/fnins.2015.00487  0.76
2015 Wang X, Zhang Y, Peng Y, Hutchinson MR, Rice KC, Yin H, Watkins LR. Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as Toll-like receptor 4 antagonists. British Journal of Pharmacology. PMID 26603732 DOI: 10.1111/bph.13394  0.76
2015 Zhang C, Kuo CC, Moghadam SH, Monte L, Campbell SN, Rice KC, Sawchenko PE, Masliah E, Rissman RA. Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26555315 DOI: 10.1016/j.jalz.2015.09.007  0.76
2015 Ayanwuyi LO, Stopponi S, Ubaldi M, Cippitelli A, Nasuti C, Damadzic R, Heilig M, Schank J, Cheng K, Rice KC, Ciccocioppo R. Neurokinin 1 receptor blockade in the medial amygdala attenuates alcohol drinking in rats with innate anxiety but not in wistar rats. British Journal of Pharmacology. PMID 26275374 DOI: 10.1111/bph.13280  0.76
2015 King HE, Wakeford A, Taylor W, Wetzell B, Rice KC, Riley AL. Sex differences in 3,4-methylenedioxypyrovalerone (MDPV)-induced taste avoidance and place preferences. Pharmacology, Biochemistry, and Behavior. 137: 16-22. PMID 26216834 DOI: 10.1016/j.pbb.2015.07.013  0.76
2015 Wahid HH, Dorian C, Yin Chin P, Hutchinson MR, Rice KC, Olson DM, Moldenhauer LM, Robertson SA. Toll-like receptor 4 is an essential upstream regulator of on-time parturition and perinatal viability in mice. Endocrinology. EN20151089. PMID 26151355 DOI: 10.1210/EN.2015-1089  0.76
2015 Anastasio NC, Stutz SJ, Fink LH, Swinford-Jackson SE, Sears RM, DiLeone RJ, Rice KC, Moeller FG, Cunningham KA. Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity. Acs Chemical Neuroscience. PMID 26120876 DOI: 10.1021/acschemneuro.5b00094  0.88
2015 Flax SM, Wakeford AG, Cheng K, Rice KC, Riley AL. Effect of norbinaltorphimine on ∆(9)-tetrahydrocannabinol (THC)-induced taste avoidance in adolescent and adult Sprague-Dawley rats. Psychopharmacology. PMID 26025420 DOI: 10.1007/s00213-015-3970-6  0.76
2015 Selfridge BR, Wang X, Zhang Y, Yin H, Grace PM, Watkins LR, Jacobson AE, Rice KC. Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists. Journal of Medicinal Chemistry. 58: 5038-52. PMID 26010811 DOI: 10.1021/acs.jmedchem.5b00426  0.88
2015 Jalah R, Torres OB, Mayorov AV, Li F, Antoline JF, Jacobson AE, Rice KC, Deschamps JR, Beck Z, Alving CR, Matyas GR. Efficacy, but Not Antibody Titer or Affinity, of a Heroin Hapten Conjugate Vaccine Correlates with Increasing Hapten Densities on Tetanus Toxoid, but Not on CRM197 Carriers. Bioconjugate Chemistry. 26: 1041-53. PMID 25970207 DOI: 10.1021/acs.bioconjchem.5b00085  0.88
2015 Blasio A, Valenza M, Iyer MR, Rice KC, Steardo L, Hayashi T, Cottone P, Sabino V. Sigma-1 receptor mediates acquisition of alcohol drinking and seeking behavior in alcohol-preferring rats. Behavioural Brain Research. 287: 315-22. PMID 25848705 DOI: 10.1016/j.bbr.2015.03.065  0.88
2015 Grace PM, Shimizu K, Strand KA, Rice KC, Deng G, Watkins LR, Herson PS. (+)-Naltrexone is neuroprotective and promotes alternative activation in the mouse hippocampus after cardiac arrest/cardiopulmonary resuscitation. Brain, Behavior, and Immunity. 48: 115-22. PMID 25774010 DOI: 10.1016/j.bbi.2015.03.005  0.88
2015 Suzuki M, Deschamps JR, Jacobson AE, Rice KC. Chiral resolution and absolute configuration of the enantiomers of the psychoactive "designer drug" 3,4-methylenedioxypyrovalerone. Chirality. 27: 287-93. PMID 25727807 DOI: 10.1002/chir.22423  0.88
2015 Fink LH, Anastasio NC, Fox RG, Rice KC, Moeller FG, Cunningham KA. Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1957-68. PMID 25666313 DOI: 10.1038/npp.2015.46  0.88
2015 Zhang C, Kuo CC, Moghadam SH, Monte L, Rice KC, Rissman RA. Corticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer’s Disease Transgenic Mouse Model. Journal of Alzheimer's Disease : Jad. 45: 639-50. PMID 25649650 DOI: 10.3233/JAD-141722  0.76
2015 Northcutt AL, Hutchinson MR, Wang X, Baratta MV, Hiranita T, Cochran TA, Pomrenze MB, Galer EL, Kopajtic TA, Li CM, Amat J, Larson G, Cooper DC, Huang Y, O'Neill CE, ... ... Rice KC, et al. DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. Molecular Psychiatry. PMID 25644383 DOI: 10.1038/mp.2014.177  0.88
2015 Iyer MR, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena 49. N-substituted rac-cis-4a-arylalkyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols. European Journal of Medicinal Chemistry. 92: 531-9. PMID 25599950 DOI: 10.1016/j.ejmech.2015.01.025  0.88
2015 Corrigan F, Wu Y, Tuke J, Coller JK, Rice KC, Diener KR, Hayball JD, Watkins LR, Somogyi AA, Hutchinson MR. Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling. Brain, Behavior, and Immunity. 45: 245-52. PMID 25542736 DOI: 10.1016/j.bbi.2014.12.019  0.88
2015 King HE, Wetzell B, Rice KC, Riley AL. An assessment of MDPV-induced place preference in adult Sprague-Dawley rats. Drug and Alcohol Dependence. 146: 116-9. PMID 25468817 DOI: 10.1016/j.drugalcdep.2014.11.002  0.88
2015 Altarifi AA, Rice KC, Negus SS. Effects of μ-opioid receptor agonists in assays of acute pain-stimulated and pain-depressed behavior in male rats: role of μ-agonist efficacy and noxious stimulus intensity. The Journal of Pharmacology and Experimental Therapeutics. 352: 208-17. PMID 25406170 DOI: 10.1124/jpet.114.219873  0.76
2015 Lewis SS, Hutchinson MR, Frick MM, Zhang Y, Maier SF, Sammakia T, Rice KC, Watkins LR. Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain. Brain, Behavior, and Immunity. 44: 128-36. PMID 25218902 DOI: 10.1016/j.bbi.2014.09.004  0.76
2015 Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's Disease : Jad. 43: 967-76. PMID 25125464 DOI: 10.3233/JAD-141281  0.76
2015 Carbonaro TM, Eshleman AJ, Forster MJ, Cheng K, Rice KC, Gatch MB. The role of 5-HT2A, 5-HT 2C and mGlu2 receptors in the behavioral effects of tryptamine hallucinogens N,N-dimethyltryptamine and N,N-diisopropyltryptamine in rats and mice. Psychopharmacology. 232: 275-84. PMID 24985890 DOI: 10.1007/s00213-014-3658-3  0.88
2015 Schank JR, Nelson BS, Damadzic R, Tapocik JD, Yao M, King CE, Rowe KE, Cheng K, Rice KC, Heilig M. Neurokinin-1 receptor antagonism attenuates neuronal activity triggered by stress-induced reinstatement of alcohol seeking Neuropharmacology. 99: 106-114. DOI: 10.1016/j.neuropharm.2015.07.009  0.76
2015 Bachtell R, Hutchinson MR, Wang X, Rice KC, Maier SF, Watkins LR. Targeting the toll of drug abuse: The translational potential of toll-like receptor 4 Cns and Neurological Disorders - Drug Targets. 14: 692-698.  0.88
2014 King HE, Wetzell B, Rice KC, Riley AL. 3,4-methylenedioxypyrovalerone (MDPV)-induced conditioned taste avoidance in the F344/N and LEW rat strains. Pharmacology, Biochemistry, and Behavior. 126: 163-9. PMID 25284129 DOI: 10.1016/j.pbb.2014.09.021  0.88
2014 Leitl MD, Potter DN, Cheng K, Rice KC, Carlezon WA, Negus SS. Sustained pain-related depression of behavior: effects of intraplantar formalin and complete freund's adjuvant on intracranial self-stimulation (ICSS) and endogenous kappa opioid biomarkers in rats. Molecular Pain. 10: 62. PMID 25245060 DOI: 10.1186/1744-8069-10-62  0.88
2014 Grace PM, Ramos KM, Rodgers KM, Wang X, Hutchinson MR, Lewis MT, Morgan KN, Kroll JL, Taylor FR, Strand KA, Zhang Y, Berkelhammer D, Huey MG, Greene LI, Cochran TA, ... ... Rice KC, et al. Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae. Neuroscience. 280: 299-317. PMID 25241065 DOI: 10.1016/j.neuroscience.2014.09.020  0.88
2014 Micioni Di Bonaventura MV, Ciccocioppo R, Romano A, Bossert JM, Rice KC, Ubaldi M, St Laurent R, Gaetani S, Massi M, Shaham Y, Cifani C. Role of bed nucleus of the stria terminalis corticotrophin-releasing factor receptors in frustration stress-induced binge-like palatable food consumption in female rats with a history of food restriction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11316-24. PMID 25143612 DOI: 10.1523/JNEUROSCI.1854-14.2014  0.88
2014 Zwicker JD, Zhang Y, Ren J, Hutchinson MR, Rice KC, Watkins LR, Greer JJ, Funk GD. Glial TLR4 signaling does not contribute to opioid-induced depression of respiration. Journal of Applied Physiology (Bethesda, Md. : 1985). 117: 857-68. PMID 25103966 DOI: 10.1152/japplphysiol.00534.2014  0.88
2014 Torres OB, Jalah R, Rice KC, Li F, Antoline JF, Iyer MR, Jacobson AE, Boutaghou MN, Alving CR, Matyas GR. Characterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines. Analytical and Bioanalytical Chemistry. 406: 5927-37. PMID 25084736 DOI: 10.1007/s00216-014-8035-x  0.88
2014 Blasio A, Rice KC, Sabino V, Cottone P. Characterization of a shortened model of diet alternation in female rats: effects of the CB1 receptor antagonist rimonabant on food intake and anxiety-like behavior. Behavioural Pharmacology. 25: 609-17. PMID 25011007 DOI: 10.1097/FBP.0000000000000059  0.88
2014 Li F, Cheng K, Antoline JF, Iyer MR, Matyas GR, Torres OB, Jalah R, Beck Z, Alving CR, Parrish DA, Deschamps JR, Jacobson AE, Rice KC. Synthesis and immunological effects of heroin vaccines. Organic & Biomolecular Chemistry. 12: 7211-32. PMID 24995943 DOI: 10.1039/c4ob01053a  0.88
2014 Mabrouk OS, Dripps IJ, Ramani S, Chang C, Han JL, Rice KC, Jutkiewicz EM. Automated touch screen device for recording complex rodent behaviors. Journal of Neuroscience Methods. 233: 129-36. PMID 24952323 DOI: 10.1016/j.jneumeth.2014.05.004  0.88
2014 Dong H, Wang S, Zeng Z, Li F, Montalvo-Ortiz J, Tucker C, Akhtar S, Shi J, Meltzer HY, Rice KC, Csernansky JG. Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice. Psychopharmacology. 231: 4711-22. PMID 24862368 DOI: 10.1007/s00213-014-3629-8  0.88
2014 Augier E, Flanigan M, Dulman RS, Pincus A, Schank JR, Rice KC, Kejun C, Heilig M, Tapocik JD. Wistar rats acquire and maintain self-administration of 20 % ethanol without water deprivation, saccharin/sucrose fading, or extended access training. Psychopharmacology. 231: 4561-8. PMID 24858375 DOI: 10.1007/s00213-014-3605-3  0.88
2014 Selfridge BR, Deschamps JR, Jacobson AE, Rice KC. Synthesis of enantiopure 10-nornaltrexones in the search for Toll-like receptor 4 antagonists and opioid ligands. The Journal of Organic Chemistry. 79: 5007-18. PMID 24773391 DOI: 10.1021/jo500568s  0.88
2014 Bajo M, Madamba SG, Roberto M, Blednov YA, Sagi VN, Roberts E, Rice KC, Harris RA, Siggins GR. Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala. Brain, Behavior, and Immunity. 40: 191-202. PMID 24675033 DOI: 10.1016/j.bbi.2014.03.007  0.88
2014 Matyas GR, Rice KC, Cheng K, Li F, Antoline JF, Iyer MR, Jacobson AE, Mayorov AV, Beck Z, Torres OB, Alving CR. Facial recognition of heroin vaccine opiates: type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine. Vaccine. 32: 1473-9. PMID 24486371 DOI: 10.1016/j.vaccine.2014.01.028  0.88
2014 Kupchik YM, Scofield MD, Rice KC, Cheng K, Roques BP, Kalivas PW. Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1057-66. PMID 24431463 DOI: 10.1523/JNEUROSCI.4336-13.2014  0.88
2014 Ellis A, Wieseler J, Favret J, Johnson KW, Rice KC, Maier SF, Falci S, Watkins LR. Systemic administration of propentofylline, ibudilast, and (+)-naltrexone each reverses mechanical allodynia in a novel rat model of central neuropathic pain. The Journal of Pain : Official Journal of the American Pain Society. 15: 407-21. PMID 24412802 DOI: 10.1016/j.jpain.2013.12.007  0.88
2014 Xiong W, Chen SR, He L, Cheng K, Zhao YL, Chen H, Li DP, Homanics GE, Peever J, Rice KC, Wu LG, Pan HL, Zhang L. Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease. Nature Neuroscience. 17: 232-9. PMID 24390226 DOI: 10.1038/nn.3615  0.88
2014 Sukhtankar DD, Lee H, Rice KC, Ko MC. Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain Psychopharmacology. 231: 1377-1387. PMID 24217900 DOI: 10.1007/s00213-013-3341-0  0.88
2014 Schank JR, King CE, Sun H, Cheng K, Rice KC, Heilig M, Weinshenker D, Schroeder JP. The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1093-101. PMID 24173499 DOI: 10.1038/npp.2013.309  0.88
2014 Merluzzi AP, Hurwitz ZE, Briscione MA, Cobuzzi JL, Wetzell B, Rice KC, Riley AL. Age-dependent MDPV-induced taste aversions and thermoregulation in adolescent and adult rats. Developmental Psychobiology. 56: 943-54. PMID 24122728 DOI: 10.1002/dev.21171  0.88
2014 Leitl MD, Onvani S, Bowers MS, Cheng K, Rice KC, Carlezon WA, Banks ML, Negus SS. Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 614-24. PMID 24008352 DOI: 10.1038/npp.2013.236  0.88
2014 Dore R, Valenza M, Wang X, Rice KC, Sabino V, Cottone P. The inverse agonist of CB1 receptor SR141716 blocks compulsive eating of palatable food. Addiction Biology. 19: 849-61. PMID 23587012 DOI: 10.1111/adb.12056  0.88
2014 Anizan S, Ellefsen K, Concheiro M, Suzuki M, Rice KC, Baumann MH, Huestis MA. 3,4-Methylenedioxypyrovalerone (MDPV) and metabolites quantification in human and rat plasma by liquid chromatography-high resolution mass spectrometry Analytica Chimica Acta. 827: 54-63. DOI: 10.1016/j.aca.2014.04.015  0.88
2013 Murnane KS, Winschel J, Schmidt KT, Stewart LM, Rose SJ, Cheng K, Rice KC, Howell LL. Serotonin 2A receptors differentially contribute to abuse-related effects of cocaine and cocaine-induced nigrostriatal and mesolimbic dopamine overflow in nonhuman primates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13367-74. PMID 23946394 DOI: 10.1523/JNEUROSCI.1437-13.2013  0.88
2013 Altarifi AA, Rice KC, Negus SS. Abuse-related effects of μ-opioid analgesics in an assay of intracranial self-stimulation in rats: Modulation by chronic morphine exposure Behavioural Pharmacology. 24: 459-470. PMID 23881045 DOI: 10.1097/FBP.0b013e328364c0bd  0.88
2013 Lim HJ, Dersch CM, Rothman RB, Deschamps JR, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 48. C7- and C8-substituted 5-phenylmorphan opioids from diastereoselective alkylation. European Journal of Medicinal Chemistry. 67: 335-43. PMID 23880358 DOI: 10.1016/j.ejmech.2013.06.030  0.88
2013 Murnane KS, Andersen ML, Rice KC, Howell LL. Selective serotonin 2A receptor antagonism attenuates the effects of amphetamine on arousal and dopamine overflow in non-human primates. Journal of Sleep Research. 22: 581-8. PMID 23879373 DOI: 10.1111/jsr.12045  0.88
2013 Blasio A, Iemolo A, Sabino V, Petrosino S, Steardo L, Rice KC, Orlando P, Iannotti FA, Di Marzo V, Zorrilla EP, Cottone P. Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2498-507. PMID 23793355 DOI: 10.1038/npp.2013.153  0.88
2013 Iemolo A, Blasio A, St Cyr SA, Jiang F, Rice KC, Sabino V, Cottone P. CRF-CRF1 receptor system in the central and basolateral nuclei of the amygdala differentially mediates excessive eating of palatable food. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2456-66. PMID 23748225 DOI: 10.1038/npp.2013.147  0.88
2013 Li W, Shi X, Wang L, Guo T, Wei T, Cheng K, Rice KC, Kingery WS, Clark JD. Epidermal adrenergic signaling contributes to inflammation and pain sensitization in a rat model of complex regional pain syndrome. Pain. 154: 1224-36. PMID 23718987 DOI: 10.1016/j.pain.2013.03.033  0.88
2013 Gatch MB, Kozlenkov A, Huang RQ, Yang W, Nguyen JD, González-Maeso J, Rice KC, France CP, Dillon GH, Forster MJ, Schetz JA. The HIV antiretroviral drug efavirenz has LSD-like properties. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2373-84. PMID 23702798 DOI: 10.1038/npp.2013.135  0.88
2013 Matyas GR, Mayorov AV, Rice KC, Jacobson AE, Cheng K, Iyer MR, Li F, Beck Z, Janda KD, Alving CR. Liposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs. Vaccine. 31: 2804-10. PMID 23624097 DOI: 10.1016/j.vaccine.2013.04.027  0.88
2013 Iyer MR, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 47. Novel C4a- and N-substituted-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols. Bioorganic & Medicinal Chemistry. 21: 3298-309. PMID 23618710 DOI: 10.1016/j.bmc.2013.02.060  0.88
2013 Birdsong WT, Arttamangkul S, Clark MJ, Cheng K, Rice KC, Traynor JR, Williams JT. Increased agonist affinity at the μ-opioid receptor induced by prolonged agonist exposure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4118-27. PMID 23447620 DOI: 10.1523/JNEUROSCI.4187-12.2013  0.88
2013 Schank JR, Tapocik JD, Barbier E, Damadzic R, Eskay RL, Sun H, Rowe KE, King CE, Yao M, Flanigan ME, Solomon MG, Karlsson C, Cheng K, Rice KC, Heilig M. Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats. Biological Psychiatry. 73: 774-81. PMID 23419547 DOI: 10.1016/j.biopsych.2012.12.027  0.88
2013 Briscione MA, Serafine KM, Merluzzi AP, Rice KC, Riley AL. The effects of the 5-HT3 receptor antagonist tropisetron on cocaine-induced conditioned taste aversions. Pharmacology, Biochemistry, and Behavior. 105: 112-7. PMID 23415734 DOI: 10.1016/j.pbb.2013.02.003  0.88
2013 Theberge FR, Li X, Kambhampati S, Pickens CL, St Laurent R, Bossert JM, Baumann MH, Hutchinson MR, Rice KC, Watkins LR, Shaham Y. Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving. Biological Psychiatry. 73: 729-37. PMID 23384483 DOI: 10.1016/j.biopsych.2012.12.019  0.88
2013 Lewis SS, Hutchinson MR, Zhang Y, Hund DK, Maier SF, Rice KC, Watkins LR. Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain. Brain, Behavior, and Immunity. 30: 24-32. PMID 23348028 DOI: 10.1016/j.bbi.2013.01.005  0.88
2013 Cunningham KA, Anastasio NC, Fox RG, Stutz SJ, Bubar MJ, Swinford SE, Watson CS, Gilbertson SR, Rice KC, Rosenzweig-Lipson S, Moeller FG. Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction. Acs Chemical Neuroscience. 4: 110-21. PMID 23336050 DOI: 10.1021/cn300072u  0.88
2013 Jutkiewicz EM, Rice KC, Carroll FI, Woods JH. Patterns of nicotinic receptor antagonism II: cardiovascular effects in rats. Drug and Alcohol Dependence. 131: 284-97. PMID 23333294 DOI: 10.1016/j.drugalcdep.2012.12.021  0.88
2013 Barbier E, Vendruscolo LF, Schlosburg JE, Edwards S, Juergens N, Park PE, Misra KK, Cheng K, Rice KC, Schank J, Schulteis G, Koob GF, Heilig M. The NK1 receptor antagonist L822429 reduces heroin reinforcement. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 976-84. PMID 23303056 DOI: 10.1038/npp.2012.261  0.88
2013 Koek W, Cheng K, Rice KC. Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: Comparison with GABAB receptor agonists and drugs of abuse Journal of Pharmacology and Experimental Therapeutics. 344: 553-560. PMID 23275067 DOI: 10.1124/jpet.112.202226  0.88
2013 Sulima A, Cheng K, Jacobson AE, Rice KC, Gawrisch K, Lee YS. Z and e rotamers of N-formyl-1-bromo-4-hydroxy-3-methoxymorphinan-6-one and their interconversion as studied by 1H/13C NMR spectroscopy and quantum chemical calculations Magnetic Resonance in Chemistry. 51: 82-88. PMID 23233124 DOI: 10.1002/mrc.3909  0.88
2013 Fantegrossi WE, Gannon BM, Zimmerman SM, Rice KC. In vivo effects of abused 'bath salt' constituent 3,4- methylenedioxypyrovalerone (MDPV) in mice: Drug discrimination, thermoregulation, and locomotor activity Neuropsychopharmacology. 38: 563-573. PMID 23212455 DOI: 10.1038/npp.2012.233  0.88
2013 Sabino V, Kwak J, Rice KC, Cottone P. Pharmacological characterization of the 20% alcohol intermittent access model in Sardinian alcohol-preferring rats: a model of binge-like drinking. Alcoholism, Clinical and Experimental Research. 37: 635-43. PMID 23126554 DOI: 10.1111/acer.12008  0.88
2013 Li JX, Shah AP, Patel SK, Rice KC, France CP. Modification of the behavioral effects of morphine in rats by serotonin 5-HT₁A and 5-HTâ‚‚A receptor agonists: antinociception, drug discrimination, and locomotor activity. Psychopharmacology. 225: 791-801. PMID 22993050 DOI: 10.1007/s00213-012-2870-2  0.88
2012 Guo TZ, Wei T, Shi X, Li WW, Hou S, Wang L, Tsujikawa K, Rice KC, Cheng K, Clark DJ, Kingery WS. Neuropeptide deficient mice have attenuated nociceptive, vascular, and inflammatory changes in a tibia fracture model of complex regional pain syndrome. Molecular Pain. 8: 85. PMID 23191958 DOI: 10.1186/1744-8069-8-85  0.88
2012 Li F, Deck JA, Dersch CM, Rothman RB, Deschamps JR, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 46. N-substituted-2,3,4,9, 10,10a-hexahydro-1H-1,4a-(epiminoethano)phenanthren-6- and 8-ols - Carbocyclic relatives of f-oxide-bridged phenylmorphans European Journal of Medicinal Chemistry. 58: 557-567. PMID 23168379 DOI: 10.1016/j.ejmech.2012.10.041  0.88
2012 Yekkirala AS, Banks ML, Lunzer MM, Negus SS, Rice KC, Portoghese PS. Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys. Acs Chemical Neuroscience. 3: 720-7. PMID 23019498 DOI: 10.1021/cn300049m  0.88
2012 Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, ... ... Rice KC, et al. Opioid activation of toll-like receptor 4 contributes to drug reinforcement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11187-200. PMID 22895704 DOI: 10.1523/JNEUROSCI.0684-12.2012  0.88
2012 Tam J, Cinar R, Liu J, Godlewski G, Wesley D, Jourdan T, Szanda G, Mukhopadhyay B, Chedester L, Liow JS, Innis RB, Cheng K, Rice KC, Deschamps JR, Chorvat RJ, et al. Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance Cell Metabolism. 16: 167-179. PMID 22841573 DOI: 10.1016/j.cmet.2012.07.002  0.88
2012 Koffarnus MN, Collins GT, Rice KC, Chen J, Woods JH, Winger G. Self-administration of agonists selective for dopamine D2, D3, and D4 receptors by rhesus monkeys. Behavioural Pharmacology. 23: 331-8. PMID 22785383 DOI: 10.1097/FBP.0b013e3283564dbb  0.88
2012 Parylak SL, Cottone P, Sabino V, Rice KC, Zorrilla EP. Effects of CB1 and CRF1 receptor antagonists on binge-like eating in rats with limited access to a sweet fat diet: lack of withdrawal-like responses. Physiology & Behavior. 107: 231-42. PMID 22776620 DOI: 10.1016/j.physbeh.2012.06.017  0.88
2012 Cottone P, Wang X, Park JW, Valenza M, Blasio A, Kwak J, Iyer MR, Steardo L, Rice KC, Hayashi T, Sabino V. Antagonism of sigma-1 receptors blocks compulsive-like eating. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2593-604. PMID 22713906 DOI: 10.1038/npp.2012.89  0.88
2012 Serafine KM, Briscione MA, Rice KC, Riley AL. Dopamine mediates cocaine-induced conditioned taste aversions as demonstrated with cross-drug preexposure to GBR 12909. Pharmacology, Biochemistry, and Behavior. 102: 269-74. PMID 22579912 DOI: 10.1016/j.pbb.2012.04.012  0.88
2012 Lewis SS, Loram LC, Hutchinson MR, Li CM, Zhang Y, Maier SF, Huang Y, Rice KC, Watkins LR. (+)-naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats. The Journal of Pain : Official Journal of the American Pain Society. 13: 498-506. PMID 22520687 DOI: 10.1016/j.jpain.2012.02.005  0.88
2012 Rissman RA, Staup MA, Lee AR, Justice NJ, Rice KC, Vale W, Sawchenko PE. Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation. Proceedings of the National Academy of Sciences of the United States of America. 109: 6277-82. PMID 22451915 DOI: 10.1073/pnas.1203140109  0.88
2012 Sawyer EK, Mun J, Nye JA, Kimmel HL, Voll RJ, Stehouwer JS, Rice KC, Goodman MM, Howell LL. Neurobiological changes mediating the effects of chronic fluoxetine on cocaine use. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1816-24. PMID 22434223 DOI: 10.1038/npp.2012.29  0.88
2012 Negus SS, Rosenberg MB, Altarifi AA, O'Connell RH, Folk JE, Rice KC. Effects of the delta opioid receptor agonist SNC80 on pain-related depression of intracranial self-stimulation (ICSS) in rats Journal of Pain. 13: 317-327. PMID 22424913 DOI: 10.1016/j.jpain.2011.12.003  0.88
2012 Boos TL, Cheng K, Greiner E, Deschamps JR, Jacobson AE, Rice KC. Configurational reassignment and improved preparation of the competitive IL-6 receptor antagonist 20 R,21 R-epoxyresibufogenin-3-formate Journal of Natural Products. 75: 661-668. PMID 22360661 DOI: 10.1021/np2008957  0.88
2012 Iyer MR, Lee YS, Deschamps JR, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity. European Journal of Medicinal Chemistry. 50: 44-54. PMID 22341895 DOI: 10.1016/j.ejmech.2012.01.025  0.88
2012 Koek W, France CP, Cheng K, Rice KC. Effects of the GABAB receptor-positive modulators CGP7930 and rac-BHFF in baclofen- and γ-hydroxybutyrate-discriminating pigeons. The Journal of Pharmacology and Experimental Therapeutics. 341: 369-76. PMID 22319197 DOI: 10.1124/jpet.111.190975  0.88
2012 Murnane KS, Kimmel HL, Rice KC, Howell LL. The neuropharmacology of prolactin secretion elicited by 3,4-methylenedioxymethamphetamine ("ecstasy"): a concurrent microdialysis and plasma analysis study. Hormones and Behavior. 61: 181-90. PMID 22197270 DOI: 10.1016/j.yhbeh.2011.10.012  0.88
2012 Kimura T, Yeliseev AA, Vukoti K, Rhodes SD, Cheng K, Rice KC, Gawrisch K. Recombinant cannabinoid type 2 receptor in liposome model activates g protein in response to anionic lipid constituents. The Journal of Biological Chemistry. 287: 4076-87. PMID 22134924 DOI: 10.1074/jbc.M111.268425  0.88
2012 Negus SS, O'Connell R, Morrissey E, Cheng K, Rice KC. Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in rats Journal of Pharmacology and Experimental Therapeutics. 340: 501-509. PMID 22128346 DOI: 10.1124/jpet.111.186783  0.88
2012 Wu Y, Lousberg EL, Moldenhauer LM, Hayball JD, Coller JK, Rice KC, Watkins LR, Somogyi AA, Hutchinson MR. Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice. British Journal of Pharmacology. 165: 1319-29. PMID 21955045 DOI: 10.1111/j.1476-5381.2011.01572.x  0.88
2012 Hensler JG, Advani T, Burke TF, Cheng K, Rice KC, Koek W. GABAB receptor-positive modulators: brain region-dependent effects. The Journal of Pharmacology and Experimental Therapeutics. 340: 19-26. PMID 21954301 DOI: 10.1124/jpet.111.186577  0.88
2012 Negus SS, Morrissey EM, Folk JE, Rice KC. Interaction between mu and delta opioid receptor agonists in an assay of capsaicin-induced thermal allodynia in rhesus monkeys Pain Research and Treatment. 2012. DOI: 10.1155/2012/867067  0.88
2011 Lim HJ, Deschamps JR, Jacobson AE, Rice KC. Diastereoselective One-Pot Synthesis of 7- and 8-Substituted 5-Phenylmorphans Organic Letters. 13: 5322-5325. PMID 21905747 DOI: 10.1021/ol2021862  0.88
2011 Hutchinson MR, Shavit Y, Grace PM, Rice KC, Maier SF, Watkins LR. Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacological Reviews. 63: 772-810. PMID 21752874 DOI: 10.1124/pr.110.004135  0.88
2011 Jutkiewicz EM, Brooks EA, Kynaston AD, Rice KC, Woods JH. Patterns of nicotinic receptor antagonism: nicotine discrimination studies. The Journal of Pharmacology and Experimental Therapeutics. 339: 194-202. PMID 21730011 DOI: 10.1124/jpet.111.182170  0.88
2011 Koffarnus MN, Newman AH, Grundt P, Rice KC, Woods JH. Effects of selective dopaminergic compounds on a delay-discounting task. Behavioural Pharmacology. 22: 300-11. PMID 21694584 DOI: 10.1097/FBP.0b013e3283473bcb  0.88
2011 Li F, Folk JE, Cheng K, Kurimura M, Deck JA, Deschamps JR, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: compounds with moderate to low opioid-receptor affinity. Bioorganic & Medicinal Chemistry. 19: 4330-7. PMID 21684752 DOI: 10.1016/j.bmc.2011.05.035  0.88
2011 Winter JC, Amorosi DJ, Rice KC, Cheng K, Yu AM. Stimulus control by 5-methoxy-N,N-dimethyltryptamine in wild-type and CYP2D6-humanized mice. Pharmacology, Biochemistry, and Behavior. 99: 311-5. PMID 21624387 DOI: 10.1016/j.pbb.2011.05.015  0.88
2011 Kim JH, Deschamps JR, Rothman RB, Dersch CM, Folk JE, Cheng K, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. Part 42: Synthesis and in vitro pharmacological characterization of the N-methyl and N-phenethyl analogues of the racemic ortho-c and para-c oxide-bridged phenylmorphans Bioorganic and Medicinal Chemistry. 19: 3434-3443. PMID 21570305 DOI: 10.1016/j.bmc.2011.04.028  0.88
2011 Anastasio NC, Stoffel EC, Fox RG, Bubar MJ, Rice KC, Moeller FG, Cunningham KA. Serotonin (5-hydroxytryptamine) 5-HT(2A) receptor: association with inherent and cocaine-evoked behavioral disinhibition in rats. Behavioural Pharmacology. 22: 248-61. PMID 21499079 DOI: 10.1097/FBP.0b013e328345f90d  0.88
2011 Xiong W, Cheng K, Cui T, Godlewski G, Rice KC, Xu Y, Zhang L. Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia. Nature Chemical Biology. 7: 296-303. PMID 21460829 DOI: 10.1038/nchembio.552  0.88
2011 Banks ML, Roma PG, Folk JE, Rice KC, Negus SS. Effects of the delta-opioid agonist SNC80 on the abuse liability of methadone in rhesus monkeys: a behavioral economic analysis. Psychopharmacology. 216: 431-9. PMID 21369752 DOI: 10.1007/s00213-011-2235-2  0.88
2011 Sabino V, Cottone P, Blasio A, Iyer MR, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP. Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1207-18. PMID 21346735 DOI: 10.1038/npp.2011.5  0.88
2011 Schank JR, Pickens CL, Rowe KE, Cheng K, Thorsell A, Rice KC, Shaham Y, Heilig M. Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429. Psychopharmacology. 218: 111-9. PMID 21340476 DOI: 10.1007/s00213-011-2201-z  0.88
2011 Jagoda EM, Lang L, Mccullough K, Contoreggi C, Kim BM, Ma Y, Rice KC, Szajek LP, Eckelman WC, Kiesewetter DO. [76Br]BMK-152, a nonpeptide analogue, with high affinity and low nonspecific binding for the corticotropin-releasing factor type 1 receptor Synapse. 65: 910-918. PMID 21308801 DOI: 10.1002/syn.20919  0.88
2011 Cheng K, Lee YS, Rothman RB, Dersch CM, Bittman RW, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 41. Unusual inverse μ-agonists and potent μ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphans Journal of Medicinal Chemistry. 54: 957-969. PMID 21247164 DOI: 10.1021/jm1011676  0.88
2011 Li JX, Koek W, Rice KC, France CP. Effects of direct- and indirect-acting serotonin receptor agonists on the antinociceptive and discriminative stimulus effects of morphine in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 940-9. PMID 21209613 DOI: 10.1038/npp.2010.232  0.88
2011 Li JX, Crocker C, Koek W, Rice KC, France CP. Effects of serotonin (5-HT)1A and 5-HT2A receptor agonists on schedule-controlled responding in rats: drug combination studies. Psychopharmacology. 213: 489-97. PMID 21174080 DOI: 10.1007/s00213-010-2136-9  0.88
2010 Fantegrossi WE, Simoneau J, Cohen MS, Zimmerman SM, Henson CM, Rice KC, Woods JH. Interaction of 5-HT2A and 5-HT2C receptors in R(-)-2,5-dimethoxy-4-iodoamphetamine-elicited head twitch behavior in mice. The Journal of Pharmacology and Experimental Therapeutics. 335: 728-34. PMID 20858706 DOI: 10.1124/jpet.110.172247  0.88
2010 Rothman RB, Baumann MH, Blough BE, Jacobson AE, Rice KC, Partilla JS. Evidence for noncompetitive modulation of substrate-induced serotonin release Synapse. 64: 862-869. PMID 20842720 DOI: 10.1002/syn.20804  0.88
2010 Banks ML, Folk JE, Rice KC, Negus SS. Selective enhancement of fentanyl-induced antinociception by the delta agonist SNC162 but not by ketamine in rhesus monkeys: Further evidence supportive of delta agonists as candidate adjuncts to mu opioid analgesics. Pharmacology, Biochemistry, and Behavior. 97: 205-12. PMID 20678514 DOI: 10.1016/j.pbb.2010.07.019  0.88
2010 Banks ML, Rice KC, Negus SS. Antinociceptive interactions between Mu-opioid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy. The Journal of Pharmacology and Experimental Therapeutics. 335: 497-505. PMID 20675432 DOI: 10.1124/jpet.110.169276  0.88
2010 Koek W, France CP, Cheng K, Rice KC. GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo. The Journal of Pharmacology and Experimental Therapeutics. 335: 163-71. PMID 20628000 DOI: 10.1124/jpet.110.171116  0.88
2010 Vardanyan M, Melemedjian OK, Price TJ, Ossipov MH, Lai J, Roberts E, Boos TL, Deschamps JR, Jacobson AE, Rice KC, Porreca F. Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist. Pain. 151: 257-65. PMID 20599324 DOI: 10.1016/j.pain.2010.05.022  0.88
2010 De Bruyne S, Wyffels L, Boos TL, Staelens S, Deleye S, Rice KC, De Vos F. In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter Nuclear Medicine and Biology. 37: 469-477. PMID 20447559 DOI: 10.1016/j.nucmedbio.2009.10.006  0.88
2010 Hutchinson MR, Loram LC, Zhang Y, Shridhar M, Rezvani N, Berkelhammer D, Phipps S, Foster PS, Landgraf K, Falke JJ, Rice KC, Maier SF, Yin H, Watkins LR. Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity. Neuroscience. 168: 551-63. PMID 20381591 DOI: 10.1016/j.neuroscience.2010.03.067  0.88
2010 Hutchinson MR, Lewis SS, Coats BD, Rezvani N, Zhang Y, Wieseler JL, Somogyi AA, Yin H, Maier SF, Rice KC, Watkins LR. Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences. Neuroscience. 167: 880-93. PMID 20178837 DOI: 10.1016/j.neuroscience.2010.02.011  0.88
2010 Negus SS, Morrissey EM, Rosenberg M, Cheng K, Rice KC. Effects of kappa opioids in an assay of pain-depressed intracranial self-stimulation in rats Psychopharmacology. 209: 149-159. PMID 20101391 DOI: 10.1007/s00213-009-1770-6  0.88
2010 Negus SS, Banks ML, Folk JE, Rice KC. Modulation of delta opioid agonist-induced antinociception by repeated morphine pretreatment in rhesus monkeys. Life Sciences. 86: 385-92. PMID 20096291 DOI: 10.1016/j.lfs.2010.01.006  0.88
2010 Li JX, Koek W, Rice KC, France CP. Differential effects of serotonin 5-HT1A receptor agonists on the discriminative stimulus effects of the 5-HT2A receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rats and rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 333: 244-52. PMID 20053932 DOI: 10.1124/jpet.109.163451  0.88
2010 Iyer MR, Lee YS, Deschamps JR, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 40. N-substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ols. Bioorganic & Medicinal Chemistry. 18: 91-9. PMID 20005115 DOI: 10.1016/j.bmc.2009.11.022  0.88
2010 Sally EJ, Xu H, Dersch CM, Hsin LW, Chang LT, Prisinzano TE, Simpson DS, Giuvelis D, Rice KC, Jacobson AE, Cheng K, Bilsky EJ, Rothman RB. Identification of a novel "almost neutral" micro-opioid receptor antagonist in CHO cells expressing the cloned human mu-opioid receptor. Synapse (New York, N.Y.). 64: 280-8. PMID 19953652 DOI: 10.1002/syn.20723  0.88
2010 Lewis SS, Hutchinson MR, Rezvani N, Loram LC, Zhang Y, Maier SF, Rice KC, Watkins LR. Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta. Neuroscience. 165: 569-83. PMID 19833175 DOI: 10.1016/j.neuroscience.2009.10.011  0.88
2010 Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, ... ... Rice KC, et al. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain, Behavior, and Immunity. 24: 83-95. PMID 19679181 DOI: 10.1016/j.bbi.2009.08.004  0.88
2010 Linders JTM, Furlano DC, Mattson MV, Jacobson AE, Rice KC. Synthesis and preliminary biochemical evaluation of novel derivatives of PCP Letters in Drug Design and Discovery. 7: 79-87. DOI: 10.2174/157018010790225813  0.88
2009 Iyer MR, Deschamps JR, Jacobson AE, Rice KC. PROBES FOR NARCOTIC RECEPTOR MEDIATED PHENOMENA. 38. AN EXPEDITIOUS SYNTHESIS OF RAC-CIS-4a-ETHYL-2-METHYL-1,2,3,4,4a,9a-HEXAHYDROBENZOFURO[2,3-c]PYRIDIN-6-OL AND RAC-CIS-2-METHYL-4a-PHENETHYL-1,2,3,4,4a,9a-HEXAHYDROBENZOFURO[2,3-c]PYRIDIN-6-OL. Heterocycles. 79: 1061. PMID 20101277 DOI: 10.3987/COM-09-S(D)84  0.88
2009 Cottone P, Sabino V, Roberto M, Bajo M, Pockros L, Frihauf JB, Fekete EM, Steardo L, Rice KC, Grigoriadis DE, Conti B, Koob GF, Zorrilla EP. CRF system recruitment mediates dark side of compulsive eating. Proceedings of the National Academy of Sciences of the United States of America. 106: 20016-20. PMID 19901333 DOI: 10.1073/pnas.0908789106  0.88
2009 Hutchinson MR, Ramos KM, Loram LC, Wieseler J, Sholar PW, Kearney JJ, Lewis MT, Crysdale NY, Zhang Y, Harrison JA, Maier SF, Rice KC, Watkins LR. Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. Neuroscience. 164: 1821-32. PMID 19788917 DOI: 10.1016/j.neuroscience.2009.09.046  0.88
2009 Watkins LR, Hutchinson MR, Rice KC, Maier SF. The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia. Trends in Pharmacological Sciences. 30: 581-91. PMID 19762094 DOI: 10.1016/j.tips.2009.08.002  0.88
2009 Li JX, Unzeitig A, Javors MA, Rice KC, Koek W, France CP. Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), ketanserin, and (R)-(+)-{alpha}-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol (MDL100907) in rats. The Journal of Pharmacology and Experimental Therapeutics. 331: 671-9. PMID 19687292 DOI: 10.1124/jpet.109.157560  0.88
2009 Kreibich AS, Briand L, Cleck JN, Ecke L, Rice KC, Blendy JA. Stress-induced potentiation of cocaine reward: a role for CRF R1 and CREB. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2609-17. PMID 19675537 DOI: 10.1038/npp.2009.91  0.88
2009 Zhang Y, Lee YS, Rothman RB, Dersch CM, Deschamps JR, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 39. Enantiomeric n-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged phenylmorphans Journal of Medicinal Chemistry. 52: 7570-7579. PMID 19627147 DOI: 10.1021/jm9004225  0.88
2009 Klejbor I, Kucinski A, Wersinger SR, Corso T, Spodnik JH, Dziewiatkowski J, MoryÅ› J, Hesse RA, Rice KC, Miletich R, Stachowiak EK, Stachowiak MK. Serotonergic hyperinnervation and effective serotonin blockade in an FGF receptor developmental model of psychosis. Schizophrenia Research. 113: 308-21. PMID 19570652 DOI: 10.1016/j.schres.2009.06.006  0.88
2009 Kimura T, Cheng K, Rice KC, Gawrisch K. Location, structure, and dynamics of the synthetic cannabinoid ligand CP-55,940 in lipid bilayers Biophysical Journal. 96: 4916-4924. PMID 19527650 DOI: 10.1016/j.bpj.2009.03.033  0.88
2009 Davis CM, Rice KC, Riley AL. Opiate-agonist induced taste aversion learning in the Fischer 344 and Lewis inbred rat strains: evidence for differential mu opioid receptor activation. Pharmacology, Biochemistry, and Behavior. 93: 397-405. PMID 19508878 DOI: 10.1016/j.pbb.2009.06.001  0.88
2009 Francesconi W, Berton F, Repunte-Canonigo V, Hagihara K, Thurbon D, Lekic D, Specio SE, Greenwell TN, Chen SA, Rice KC, Richardson HN, O'Dell LE, Zorrilla EP, Morales M, Koob GF, et al. Protracted withdrawal from alcohol and drugs of abuse impairs long-term potentiation of intrinsic excitability in the juxtacapsular bed nucleus of the stria terminalis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5389-401. PMID 19403807 DOI: 10.1523/JNEUROSCI.5129-08.2009  0.88
2009 Nic Dhonnchadha BA, Fox RG, Stutz SJ, Rice KC, Cunningham KA. Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model. Behavioral Neuroscience. 123: 382-96. PMID 19331461 DOI: 10.1037/a0014592  0.88
2009 Greenwell TN, Funk CK, Cottone P, Richardson HN, Chen SA, Rice KC, Zorrilla EP, Koob GF. Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long- but not short-access rats. Addiction Biology. 14: 130-43. PMID 19291009 DOI: 10.1111/j.1369-1600.2008.00142.x  0.88
2009 Nie Z, Zorrilla EP, Madamba SG, Rice KC, Roberto M, Siggins GR. Presynaptic CRF1 receptors mediate the ethanol enhancement of GABAergic transmission in the mouse central amygdala. Thescientificworldjournal. 9: 68-85. PMID 19151899 DOI: 10.1100/tsw.2009.1  0.88
2009 Collins GT, Truccone A, Haji-Abdi F, Newman AH, Grundt P, Rice KC, Husbands SM, Greedy BM, Enguehard-Gueiffier C, Gueiffier A, Chen J, Wang S, Katz JL, Grandy DK, Sunahara RK, et al. Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice. The Journal of Pharmacology and Experimental Therapeutics. 329: 210-7. PMID 19136638 DOI: 10.1124/jpet.108.144048  0.88
2009 Do Carmo GP, Folk JE, Rice KC, Chartoff E, Carlezon WA, Negus SS. The selective non-peptidic delta opioid agonist SNC80 does not facilitate intracranial self-stimulation in rats. European Journal of Pharmacology. 604: 58-65. PMID 19133255 DOI: 10.1016/j.ejphar.2008.12.021  0.88
2009 Li JX, Rice KC, France CP. Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rhesus monkeys: antagonism and apparent pA2 analyses. The Journal of Pharmacology and Experimental Therapeutics. 328: 976-81. PMID 19098164 DOI: 10.1124/jpet.108.145458  0.88
2009 Negus SS, Bear AE, Folk JE, Rice KC. Role of delta opioid efficacy as a determinant of mu/delta opioid interactions in rhesus monkeys. European Journal of Pharmacology. 602: 92-100. PMID 19027735 DOI: 10.1016/j.ejphar.2008.11.004  0.88
2009 Kohut SJ, Roma PG, Davis CM, Zernig G, Saria A, Dominguez JM, Rice KC, Riley AL. The impact of early environmental rearing condition on the discriminative stimulus effects and Fos expression induced by cocaine in adult male and female rats. Psychopharmacology. 203: 383-97. PMID 18953528 DOI: 10.1007/s00213-008-1368-4  0.88
2009 Sabino V, Cottone P, Zhao Y, Iyer MR, Steardo L, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP. The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1482-93. PMID 18946467 DOI: 10.1038/npp.2008.192  0.88
2009 May JA, Sharif NA, Chen HH, Liao JC, Kelly CR, Glennon RA, Young R, Li JX, Rice KC, France CP. Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A [(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine]. Pharmacology, Biochemistry, and Behavior. 91: 307-14. PMID 18718483 DOI: 10.1016/j.pbb.2008.07.015  0.88
2009 Negus SS, Rice KC. Mechanisms of withdrawal-associated increases in heroin self-administration: Pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys Neuropsychopharmacology. 34: 899-911. PMID 18704098 DOI: 10.1038/npp.2008.127  0.88
2009 Davis CM, Stevenson GW, Cañadas F, Ullrich T, Rice KC, Riley AL. Discriminative stimulus properties of naloxone in Long-Evans rats: assessment with the conditioned taste aversion baseline of drug discrimination learning. Psychopharmacology. 203: 421-9. PMID 18594795 DOI: 10.1007/s00213-008-1233-5  0.88
2009 Lang L, Ma Y, Kim BM, Jagoda EM, Rice KC, Szajek LP, Contoreggi C, Gold PW, Chrousos GP, Eckelman WC, Kiesewettera DO. [76Br]BMK-I-152, a non-peptide analogue for PET imaging of corticotropin-releasing hormone type 1 receptor (CRHR1) Journal of Labelled Compounds and Radiopharmaceuticals. 52: 394-400. DOI: 10.1002/jlcr.1616  0.88
2009 De Bruyne S, Boos TL, Wyffels L, Goeman JL, Rice KC, De Vos F. Synthesis, radiosynthesis and in vivo evaluation of [123I]-4-(2- (bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine as a selective tracer for imaging the dopamine transporter Journal of Labelled Compounds and Radiopharmaceuticals. 52: 304-311. DOI: 10.1002/jlcr.1603  0.88
2008 Kurimura M, Liu H, Sulima A, Hashimoto A, Przybyl AK, Ohshima E, Kodato S, Deschamps JR, Dersch CM, Rothman RB, Yong SL, Jacobson AE, Rice KC. Probes for narcotic receptor mediated phenomena. 37.1 Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analogues of the ortho- and para-d-isomers Journal of Medicinal Chemistry. 51: 7866-7881. PMID 19053757 DOI: 10.1021/jm800913d  0.88
2008 Zezula J, Singer L, Przybył AK, Hashimoto A, Dersch CM, Rothman RB, Deschamps J, Lee YS, Jacobson AE, Rice KC. Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans. Organic & Biomolecular Chemistry. 6: 2868-83. PMID 18688479 DOI: 10.1039/b803433h  0.88
2008 Hutchinson MR, Zhang Y, Brown K, Coats BD, Shridhar M, Sholar PW, Patel SJ, Crysdale NY, Harrison JA, Maier SF, Rice KC, Watkins LR. Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). The European Journal of Neuroscience. 28: 20-9. PMID 18662331 DOI: 10.1111/j.1460-9568.2008.06321.x  0.88
2008 Roma PG, Rinker JA, Serafine KM, Chen SA, Barr CS, Cheng K, Rice KC, Riley AL. Genetic and early environmental contributions to alcohol's aversive and physiological effects. Pharmacology, Biochemistry, and Behavior. 91: 134-9. PMID 18639579 DOI: 10.1016/j.pbb.2008.06.022  0.88
2008 Do Carmo GP, Polt R, Bilsky EJ, Rice KC, Negus SS. Behavioral pharmacology of the mu/delta opioid glycopeptide MMP2200 in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 326: 939-48. PMID 18511649 DOI: 10.1124/jpet.108.138180  0.88
2008 Rutherford JM, Wang J, Xu H, Dersch CM, Partilla JS, Rice KC, Rothman RB. Evidence for a mu-delta opioid receptor complex in CHO cells co-expressing mu and delta opioid peptide receptors. Peptides. 29: 1424-31. PMID 18472184 DOI: 10.1016/j.peptides.2008.03.019  0.88
2008 Horn TL, Harder JB, Johnson WD, Curry PT, Parchment RE, Morrissey RL, Mellick PW, Calis KA, Gold PW, Rice KC, Contoreggi C, Charney DS, Cizza G, Glaze ER, Tomaszewski JE, et al. Integration of in vivo and in vitro approaches to characterize the toxicity of Antalarmin, a corticotropin-releasing hormone receptor antagonist Toxicology. 248: 8-17. PMID 18423834 DOI: 10.1016/j.tox.2008.03.002  0.88
2008 Hsin LW, Chang LT, Rothman RB, Dersch CM, Jacobson AE, Rice KC. Design and synthesis of 2- and 3-substituted-3-phenylpropyl analogs of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: Role of amino, fluoro, hydroxyl, methoxyl, methyl, methylene, and oxo substituents on affinity for the dopamine and serotonin transporters Journal of Medicinal Chemistry. 51: 2795-2806. PMID 18393401 DOI: 10.1021/jm701270n  0.88
2008 Yang X, Wang S, Rice KC, Munro CA, Wand GS. Restraint stress and ethanol consumption in two mouse strains. Alcoholism, Clinical and Experimental Research. 32: 840-52. PMID 18336636 DOI: 10.1111/j.1530-0277.2008.00632.x  0.88
2008 Pascoe JE, Williams KL, Mukhopadhyay P, Rice KC, Woods JH, Ko MC. Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic-pituitary-adrenal axis in monkeys. Psychoneuroendocrinology. 33: 478-86. PMID 18325678 DOI: 10.1016/j.psyneuen.2008.01.006  0.88
2008 Li JX, Rice KC, France CP. Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 324: 827-33. PMID 17993605 DOI: 10.1124/jpet.107.130625  0.88
2008 Cheng K, Saha B, Mahadevan A, Razdan RK, Kunos G, Jacobson AE, Rice KC. Synthesis of 2-(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenamidoethyl-d 4 dihydrogen phosphate, tetra-deuterated pAEA Journal of Labelled Compounds and Radiopharmaceuticals. 51: 389-390. DOI: 10.1002/jlcr.1540  0.88
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