Deborah J. Clegg - Publications

Internal Medicine University of Texas Southwestern Medical Center, Dallas, TX, United States 
hypothalamic regulation of adiposity

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction. Cell Metabolism. 29: 1232. PMID 31067449 DOI: 10.1016/j.cmet.2019.04.006  0.32
2016 Santiago AM, Clegg DJ, Routh VH. Ventromedial hypothalamic glucose sensing and glucose homeostasis vary throughout the estrous cycle. Physiology & Behavior. PMID 27666162 DOI: 10.1016/j.physbeh.2016.09.021  1
2016 Palmer BF, Clegg DJ. Achieving the Benefits of a High-Potassium, Paleolithic Diet, Without the Toxicity. Mayo Clinic Proceedings. PMID 26948054 DOI: 10.1016/j.mayocp.2016.01.012  1
2016 Stout MB, Steyn FJ, Jurczak MJ, Camporez JG, Zhu Y, Hawse JR, Jurk D, Palmer AK, Xu M, Pirtskhalava T, Evans GL, de Souza Santos R, Frank AP, White TA, Monroe DG, ... ... Clegg DJ, et al. 17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26809497 DOI: 10.1093/gerona/glv309  0.84
2015 Palmer BF, Clegg DJ. Electrolyte and Acid-Base Disturbances in Diabetes Mellitus. The New England Journal of Medicine. 373: 2482-3. PMID 26672863 DOI: 10.1056/NEJMc1511638  0.76
2015 Frank AP, Zechner JF, Clegg DJ. Gastric Bypass Surgery but not Caloric Restriction Improves Reproductive Function in Obese Mice. Obesity Surgery. PMID 26667161 DOI: 10.1007/s11695-015-2009-8  0.76
2015 Palmer BF, Clegg DJ. An Emerging Role of Natriuretic Peptides: Igniting the Fat Furnace to Fuel and Warm the Heart. Mayo Clinic Proceedings. PMID 26518101 DOI: 10.1016/j.mayocp.2015.08.006  0.76
2015 Palmer BF, Clegg DJ. Electrolyte and Acid-Base Disturbances in Patients with Diabetes Mellitus. The New England Journal of Medicine. 373: 548-59. PMID 26244308 DOI: 10.1056/NEJMra1503102  0.76
2015 Xu P, Cao X, He Y, Zhu L, Yang Y, Saito K, Wang C, Yan X, Hinton AO, Zou F, Ding H, Xia Y, Yan C, Shu G, Wu SP, ... ... Clegg DJ, et al. Estrogen receptor-α in medial amygdala neurons regulates body weight. The Journal of Clinical Investigation. 125: 2861-76. PMID 26098212 DOI: 10.1172/JCI80941  1
2015 Mayor RS, Finch KE, Zehr J, Morselli E, Neinast MD, Frank AP, Hahner LD, Wang J, Rakheja D, Palmer BF, Rosenfeld CR, Savani RC, Clegg DJ. Maternal high fat diet is associated with impaired fetal lung development. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00105.2015. PMID 26092997 DOI: 10.1152/ajplung.00105.2015  0.76
2015 Neinast MD, Frank AP, Zechner JF, Li Q, Vishvanath L, Palmer BF, Aguirre V, Gupta RK, Clegg DJ. Activation of natriuretic peptides and the sympathetic nervous system following Roux-en-Y gastric bypass is associated with gonadal adipose tissues browning. Molecular Metabolism. 4: 427-36. PMID 25973390 DOI: 10.1016/j.molmet.2015.02.006  0.76
2015 Waters EM, Thompson LI, Patel P, Gonzales AD, Ye HZ, Filardo EJ, Clegg DJ, Gorecka J, Akama KT, McEwen BS, Milner TA. G-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2384-97. PMID 25673833 DOI: 10.1523/JNEUROSCI.1298-14.2015  1
2015 Palmer BF, Clegg DJ. The sexual dimorphism of obesity. Molecular and Cellular Endocrinology. 402: 113-9. PMID 25578600 DOI: 10.1016/j.mce.2014.11.029  0.76
2015 Morselli E, Frank AP, Palmer BF, Rodriguez-Navas C, Criollo A, Clegg DJ. A sexually dimorphic hypothalamic response to chronic high-fat diet consumption International Journal of Obesity. DOI: 10.1038/ijo.2015.114  1
2014 Morselli E, Fuente-Martin E, Finan B, Kim M, Frank A, Garcia-Caceres C, Navas CR, Gordillo R, Neinast M, Kalainayakan SP, Li DL, Gao Y, Yi CX, Hahner L, Palmer BF, ... ... Clegg DJ, et al. Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα. Cell Reports. 9: 633-45. PMID 25373903 DOI: 10.1016/j.celrep.2014.09.025  0.76
2014 Lapid K, Lim A, Clegg DJ, Zeve D, Graff JM. Oestrogen signalling in white adipose progenitor cells inhibits differentiation into brown adipose and smooth muscle cells. Nature Communications. 5: 5196. PMID 25330806 DOI: 10.1038/ncomms6196  1
2014 Kim M, Neinast MD, Frank AP, Sun K, Park J, Zehr JA, Vishvanath L, Morselli E, Amelotte M, Palmer BF, Gupta RK, Scherer PE, Clegg DJ. ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue. Molecular Metabolism. 3: 642-51. PMID 25161887 DOI: 10.1016/j.molmet.2014.05.007  1
2014 Cao X, Xu P, Oyola MG, Xia Y, Yan X, Saito K, Zou F, Wang C, Yang Y, Hinton A, Yan C, Ding H, Zhu L, Yu L, Yang B, ... ... Clegg DJ, et al. Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice. The Journal of Clinical Investigation. 124: 4351-62. PMID 25157819 DOI: 10.1172/JCI74726  1
2014 Palmer BF, Clegg DJ. Oxygen sensing and metabolic homeostasis. Molecular and Cellular Endocrinology. 397: 51-8. PMID 25132648 DOI: 10.1016/j.mce.2014.08.001  1
2014 Park J, Morley TS, Kim M, Clegg DJ, Scherer PE. Obesity and cancer--mechanisms underlying tumour progression and recurrence. Nature Reviews. Endocrinology. 10: 455-65. PMID 24935119 DOI: 10.1038/nrendo.2014.94  0.76
2014 Frank A, Brown LM, Clegg DJ. The role of hypothalamic estrogen receptors in metabolic regulation. Frontiers in Neuroendocrinology. 35: 550-7. PMID 24882636 DOI: 10.1016/j.yfrne.2014.05.002  1
2014 Picard A, Rouch C, Kassis N, Moullé VS, Croizier S, Denis RG, Castel J, Coant N, Davis K, Clegg DJ, Benoit SC, Prévot V, Bouret S, Luquet S, Le Stunff H, et al. Hippocampal lipoprotein lipase regulates energy balance in rodents. Molecular Metabolism. 3: 167-76. PMID 24634821 DOI: 10.1016/j.molmet.2013.11.002  0.76
2014 Davis KE, Carstens EJ, Irani BG, Gent LM, Hahner LM, Clegg DJ. Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis. Hormones and Behavior. 66: 196-207. PMID 24560890 DOI: 10.1016/j.yhbeh.2014.02.004  1
2014 Palmer BF, Clegg DJ. Ascent to altitude as a weight loss method: the good and bad of hypoxia inducible factor activation. Obesity (Silver Spring, Md.). 22: 311-7. PMID 23625659 DOI: 10.1002/oby.20499  1
2014 Reizes O, Benoit SC, Clegg DJ. Neuroregulation of appetite Treatment of the Obese Patient. 3-22. DOI: 10.1007/978-1-4939-1203-2_1  0.76
2013 Clegg DJ, Palmer BF. Effects of an estrogen receptor α variant. The New England Journal of Medicine. 369: 1663-4. PMID 24152274 DOI: 10.1056/NEJMc1310364#SA1  1
2013 Davis KE, D Neinast M, Sun K, M Skiles W, D Bills J, A Zehr J, Zeve D, D Hahner L, W Cox D, M Gent L, Xu Y, V Wang Z, A Khan S, Clegg DJ. The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis. Molecular Metabolism. 2: 227-42. PMID 24049737 DOI: 10.1016/j.molmet.2013.05.006  1
2013 Fuente-Martin E, Garcia-Caceres C, Morselli E, Clegg DJ, Chowen JA, Finan B, Brinton RD, Tschöp MH. Estrogen, astrocytes and the neuroendocrine control of metabolism. Reviews in Endocrine & Metabolic Disorders. 14: 331-8. PMID 24009071 DOI: 10.1007/s11154-013-9263-7  1
2013 Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, ... ... Clegg DJ, et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. Plos Genetics. 9: e1003500. PMID 23754948 DOI: 10.1371/journal.pgen.1003500  1
2013 Mauvais-Jarvis F, Clegg DJ, Hevener AL. The role of estrogens in control of energy balance and glucose homeostasis. Endocrine Reviews. 34: 309-38. PMID 23460719 DOI: 10.1210/er.2012-1055  1
2013 Frazão R, Cravo RM, Donato J, Ratra DV, Clegg DJ, Elmquist JK, Zigman JM, Williams KW, Elias CF. Shift in Kiss1 cell activity requires estrogen receptor α. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2807-20. PMID 23407940 DOI: 10.1523/JNEUROSCI.1610-12.2013  1
2013 Brown LM, Clegg DJ. Estrogen and leptin regulation of endocrinological features of anorexia nervosa. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 237. PMID 23147480 DOI: 10.1038/npp.2012.176  1
2012 Clegg DJ. Minireview: the year in review of estrogen regulation of metabolism. Molecular Endocrinology (Baltimore, Md.). 26: 1957-60. PMID 23051593 DOI: 10.1210/me.2012-1284  1
2012 Castañeda TR, Abplanalp W, Um SH, Pfluger PT, Schrott B, Brown K, Grant E, Carnevalli L, Benoit SC, Morgan DA, Gilham D, Hui DY, Rahmouni K, Thomas G, Kozma SC, ... Clegg DJ, et al. Metabolic control by S6 kinases depends on dietary lipids. Plos One. 7: e32631. PMID 22412899 DOI: 10.1371/journal.pone.0032631  1
2012 Krikorian R, Shidler MD, Dangelo K, Couch SC, Benoit SC, Clegg DJ. Dietary ketosis enhances memory in mild cognitive impairment. Neurobiology of Aging. 33: 425.e19-27. PMID 21130529 DOI: 10.1016/j.neurobiolaging.2010.10.006  1
2011 Speakman JR, Levitsky DA, Allison DB, Bray MS, de Castro JM, Clegg DJ, Clapham JC, Dulloo AG, Gruer L, Haw S, Hebebrand J, Hetherington MM, Higgs S, Jebb SA, Loos RJ, et al. Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity. Disease Models & Mechanisms. 4: 733-45. PMID 22065844 DOI: 10.1242/dmm.008698  1
2011 Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metabolism. 14: 453-65. PMID 21982706 DOI: 10.1016/j.cmet.2011.08.009  1
2011 Holland WL, Bikman BT, Wang LP, Yuguang G, Sargent KM, Bulchand S, Knotts TA, Shui G, Clegg DJ, Wenk MR, Pagliassotti MJ, Scherer PE, Summers SA. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. The Journal of Clinical Investigation. 121: 1858-70. PMID 21490391 DOI: 10.1172/JCI43378  1
2011 Meyer MR, Clegg DJ, Prossnitz ER, Barton M. Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors. Acta Physiologica (Oxford, England). 203: 259-69. PMID 21281456 DOI: 10.1111/j.1748-1716.2010.02237.x  1
2011 Park CJ, Zhao Z, Glidewell-Kenney C, Lazic M, Chambon P, Krust A, Weiss J, Clegg DJ, Dunaif A, Jameson JL, Levine JE. Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice. The Journal of Clinical Investigation. 121: 604-12. PMID 21245576 DOI: 10.1172/JCI41702  1
2011 Clegg DJ, Gotoh K, Kemp C, Wortman MD, Benoit SC, Brown LM, D'Alessio D, Tso P, Seeley RJ, Woods SC. Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiology & Behavior. 103: 10-6. PMID 21241723 DOI: 10.1016/j.physbeh.2011.01.010  1
2011 Irani BG, Xiang Z, Yarandi HN, Holder JR, Moore MC, Bauzo RM, Proneth B, Shaw AM, Millard WJ, Chambers JB, Benoit SC, Clegg DJ, Haskell-Luevano C. Implication of the melanocortin-3 receptor in the regulation of food intake. European Journal of Pharmacology. 660: 80-7. PMID 21199647 DOI: 10.1016/j.ejphar.2010.10.101  1
2011 Davis JF, Choi DL, Clegg DJ, Benoit SC. Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice. Physiology & Behavior. 103: 39-43. PMID 21036184 DOI: 10.1016/j.physbeh.2010.10.017  1
2011 Davis JF, Choi DL, Schurdak JD, Fitzgerald MF, Clegg DJ, Lipton JW, Figlewicz DP, Benoit SC. Leptin regulates energy balance and motivation through action at distinct neural circuits. Biological Psychiatry. 69: 668-74. PMID 21035790 DOI: 10.1016/j.biopsych.2010.08.028  1
2011 Ford J, Hajibeigi A, Long M, Hahner L, Gore C, Hsieh JT, Clegg D, Zerwekh J, Öz OK. GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice Journal of Bone and Mineral Research. 26: 298-307. PMID 20734455 DOI: 10.1002/jbmr.209  1
2011 Benoit SC, Kemp CJ, Elias CF, Abplanalp W, Herman JP, Migrenne S, Lefevre AL, Cruciani-Guglielmacci C, Magnan C, Yu F, Niswender K, Irani BG, Holland WL, Clegg DJ. Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents (Journal of Clinical Investigation (2010) 120, 1 (394) DOI: 10.1172/JCI36714C1) Journal of Clinical Investigation. 121: 456.  1
2010 Zheng Q, Zhu J, Shanabrough M, Borok E, Benoit SC, Horvath TL, Clegg DJ, Reizes O. Enhanced anorexigenic signaling in lean obesity resistant syndecan-3 null mice. Neuroscience. 171: 1032-40. PMID 20923696 DOI: 10.1016/j.neuroscience.2010.09.060  1
2010 Irani BG, Donato J, Olson DP, Lowell BB, Sacktor TC, Reyland ME, Tolson KP, Zinn AR, Ueta Y, Sakata I, Zigman JM, Elias CF, Clegg DJ. Distribution and neurochemical characterization of protein kinase C-theta and -delta in the rodent hypothalamus. Neuroscience. 170: 1065-79. PMID 20691763 DOI: 10.1016/j.neuroscience.2010.07.064  1
2010 Brown LM, Gent L, Davis K, Clegg DJ. Metabolic impact of sex hormones on obesity. Brain Research. 1350: 77-85. PMID 20441773 DOI: 10.1016/j.brainres.2010.04.056  1
2010 Shi H, Sorrell JE, Clegg DJ, Woods SC, Seeley RJ. The roles of leptin receptors on POMC neurons in the regulation of sex-specific energy homeostasis. Physiology & Behavior. 100: 165-72. PMID 20193700 DOI: 10.1016/j.physbeh.2010.02.018  1
2010 Grove KL, Fried SK, Greenberg AS, Xiao XQ, Clegg DJ. A microarray analysis of sexual dimorphism of adipose tissues in high-fat-diet-induced obese mice. International Journal of Obesity (2005). 34: 989-1000. PMID 20157318 DOI: 10.1038/ijo.2010.12  1
2010 Davidson TL, Kanoski SE, Chan K, Clegg DJ, Benoit SC, Jarrard LE. Hippocampal lesions impair retention of discriminative responding based on energy state cues. Behavioral Neuroscience. 124: 97-105. PMID 20141284 DOI: 10.1037/a0018402  1
2010 Brown LM, Clegg DJ. Central effects of estradiol in the regulation of food intake, body weight, and adiposity. The Journal of Steroid Biochemistry and Molecular Biology. 122: 65-73. PMID 20035866 DOI: 10.1016/j.jsbmb.2009.12.005  1
2010 Jessen L, Clegg DJ, Bouman SD. Evaluation of the lack of anorectic effect of intracerebroventricular insulin in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R43-50. PMID 19864335 DOI: 10.1152/ajpregu.90736.2008  1
2010 Benoit SC, Kemp CJ, Elias CF, Abplanalp W, Herman JP, Migrenne S, Lefevre AL, Cruciani-Guglielmacci C, Magnan C, Yu F, Niswender K, Irani BG, Holland WL, Clegg DJ. Palmitic acid mediates hypothalamic insulin resistance by altering PKC-q subcellular localization in rodents (Journal of Clinical Investigation (2009) 119, (2577-2589)) Journal of Clinical Investigation. 120: 394. DOI: 10.1172/JCI36714C1  1
2009 Nedungadi TP, Clegg DJ. Sexual dimorphism in body fat distribution and risk for cardiovascular diseases. Journal of Cardiovascular Translational Research. 2: 321-7. PMID 20560019 DOI: 10.1007/s12265-009-9101-1  1
2009 Benoit SC, Kemp CJ, Elias CF, Abplanalp W, Herman JP, Migrenne S, Lefevre AL, Cruciani-Guglielmacci C, Magnan C, Yu F, Niswender K, Irani BG, Holland WL, Clegg DJ. Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents. The Journal of Clinical Investigation. 119: 2577-89. PMID 19726875 DOI: 10.1172/JCI36714  1
2009 Wang HH, Liu M, Clegg DJ, Portincasa P, Wang DQ. New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation. Biochimica Et Biophysica Acta. 1791: 1037-47. PMID 19589396 DOI: 10.1016/j.bbalip.2009.06.006  1
2009 Liu S, Le May C, Wong WP, Ward RD, Clegg DJ, Marcelli M, Korach KS, Mauvais-Jarvis F. Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival. Diabetes. 58: 2292-302. PMID 19587358 DOI: 10.2337/db09-0257  1
2009 Medvedovic M, Gear R, Freudenberg JM, Schneider J, Bornschein R, Yan M, Mistry MJ, Hendrix H, Karyala S, Halbleib D, Heffelfinger S, Clegg DJ, Anderson MW. Influence of fatty acid diets on gene expression in rat mammary epithelial cells. Physiological Genomics. 38: 80-8. PMID 19351911 DOI: 10.1152/physiolgenomics.00007.2009  1
2009 Shi H, Seeley RJ, Clegg DJ. Sexual differences in the control of energy homeostasis. Frontiers in Neuroendocrinology. 30: 396-404. PMID 19341761 DOI: 10.1016/j.yfrne.2009.03.004  1
2009 Shi H, Clegg DJ. Sex differences in the regulation of body weight. Physiology & Behavior. 97: 199-204. PMID 19250944 DOI: 10.1016/j.physbeh.2009.02.017  1
2009 Haas E, Bhattacharya I, Brailoiu E, Damjanović M, Brailoiu GC, Gao X, Mueller-Guerre L, Marjon NA, Gut A, Minotti R, Meyer MR, Amann K, Ammann E, Perez-Dominguez A, Genoni M, ... Clegg DJ, et al. Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity. Circulation Research. 104: 288-91. PMID 19179659 DOI: 10.1161/CIRCRESAHA.108.190892  1
2009 Posey KA, Clegg DJ, Printz RL, Byun J, Morton GJ, Vivekanandan-Giri A, Pennathur S, Baskin DG, Heinecke JW, Woods SC, Schwartz MW, Niswender KD. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. American Journal of Physiology. Endocrinology and Metabolism. 296: E1003-12. PMID 19116375 DOI: 10.1152/ajpendo.90377.2008  1
2009 Davidson TL, Chan K, Jarrard LE, Kanoski SE, Clegg DJ, Benoit SC. Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation. Hippocampus. 19: 235-52. PMID 18831000 DOI: 10.1002/hipo.20499  1
2009 Shertzer HG, Schneider SN, Kendig EL, Clegg DJ, D'Alessio DA, Johansson E, Genter MB. Tetrahydroindenoindole inhibits the progression of diabetes in mice. Chemico-Biological Interactions. 177: 71-80. PMID 18823964 DOI: 10.1016/j.cbi.2008.09.001  1
2008 Davis JF, Tracy AL, Schurdak JD, Tschöp MH, Lipton JW, Clegg DJ, Benoit SC. Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat. Behavioral Neuroscience. 122: 1257-63. PMID 19045945 DOI: 10.1037/a0013111  1
2008 Benoit SC, Tracy AL, Davis JF, Choi D, Clegg DJ. Novel functions of orexigenic hypothalamic peptides: from genes to behavior. Nutrition (Burbank, Los Angeles County, Calif.). 24: 843-7. PMID 18725081 DOI: 10.1016/j.nut.2008.06.028  1
2008 Shen L, Tso P, Woods SC, Clegg DJ, Barber KL, Carey K, Liu M. Brain apolipoprotein E: an important regulator of food intake in rats. Diabetes. 57: 2092-8. PMID 18559657 DOI: 10.2337/db08-0291  1
2008 Kendig EL, Schneider SN, Clegg DJ, Genter MB, Shertzer HG. Over-the-counter analgesics normalize blood glucose and body composition in mice fed a high fat diet. Biochemical Pharmacology. 76: 216-24. PMID 18554574 DOI: 10.1016/j.bcp.2008.05.001  1
2008 Shertzer HG, Schneider SN, Kendig EL, Clegg DJ, D'Alessio DA, Genter MB. Acetaminophen normalizes glucose homeostasis in mouse models for diabetes. Biochemical Pharmacology. 75: 1402-10. PMID 18237716 DOI: 10.1016/j.bcp.2007.12.003  1
2008 Tracy AL, Clegg DJ, Johnson JD, Davidson TL, Benoit SC. The melanocortin antagonist AgRP (83-132) increases appetitive responding for a fat, but not a carbohydrate, reinforcer. Pharmacology, Biochemistry, and Behavior. 89: 263-71. PMID 18234306 DOI: 10.1016/j.pbb.2007.12.018  1
2008 Kemp CJ, D'Alessio DA, Scott RO, Kelm GR, Meller ST, Barrera JG, Seeley RJ, Clegg DJ, Benoit SC. Voluntary consumption of ethyl oleate reduces food intake and body weight in rats. Physiology & Behavior. 93: 912-8. PMID 18234242 DOI: 10.1016/j.physbeh.2007.12.008  1
2008 Eric Hu X, Wos JA, Dowty ME, Suchanek PM, Ji W, Chambers JB, Benoit SC, Clegg DJ, Reizes O. Small-molecule melanin-concentrating hormone-1 receptor antagonists require brain penetration for inhibition of food intake and reduction in body weight. The Journal of Pharmacology and Experimental Therapeutics. 324: 206-13. PMID 17932246 DOI: 10.1124/jpet.107.130435  1
2008 Reizes O, Benoit SC, Clegg DJ. The role of syndecans in the regulation of body weight and synaptic plasticity. The International Journal of Biochemistry & Cell Biology. 40: 28-45. PMID 17698399 DOI: 10.1016/j.biocel.2007.06.011  1
2007 Davidson TL, Kanoski SE, Schier LA, Clegg DJ, Benoit SC. A potential role for the hippocampus in energy intake and body weight regulation. Current Opinion in Pharmacology. 7: 613-6. PMID 18032108 DOI: 10.1016/j.coph.2007.10.008  1
2007 Gear RB, Yan M, Schneider J, Succop P, Heffelfinger SC, Clegg DJ. Charles River Sprague Dawley rats lack early age-dependent susceptibility to DMBA-induced mammary carcinogenesis. International Journal of Biological Sciences. 3: 408-16. PMID 17940635  1
2007 Davis JF, Melhorn SJ, Shurdak JD, Heiman JU, Tschöp MH, Clegg DJ, Benoit SC. Comparison of hydrogenated vegetable shortening and nutritionally complete high-fat diet on limited access-binge behavior in rats. Physiology & Behavior. 92: 924-30. PMID 17689576 DOI: 10.1016/j.physbeh.2007.06.024  1
2007 Clegg DJ, Brown LM, Zigman JM, Kemp CJ, Strader AD, Benoit SC, Woods SC, Mangiaracina M, Geary N. Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats. Diabetes. 56: 1051-8. PMID 17251274 DOI: 10.2337/db06-0015  1
2007 Brown LM, Benoit SC, Woods SC, Clegg DJ. Intraventricular (i3vt) ghrelin increases food intake in fatty Zucker rats. Peptides. 28: 612-6. PMID 17196305 DOI: 10.1016/j.peptides.2006.11.012  1
2007 Benoit SC, Clegg DJ, Woods SC. Energy balance and feeding Handbook of Neurochemistry and Molecular Neurobiology: Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology. 619-640. DOI: 10.1007/978-0-387-30405-2_16  0.76
2006 Clegg DJ, Heffelfinger SC. Obesity: its influence on breast cancer susceptibility. Women's Health (London, England). 2: 577-85. PMID 19803965 DOI: 10.2217/17455057.2.4.577  1
2006 Duncan EA, Rider TR, Jandacek RJ, Clegg DJ, Benoit SC, Tso P, Woods SC. The regulation of alcohol intake by melanin-concentrating hormone in rats. Pharmacology, Biochemistry, and Behavior. 85: 728-35. PMID 17188345 DOI: 10.1016/j.pbb.2006.11.004  1
2006 Brown LM, Clegg DJ, Benoit SC, Woods SC. Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice. Physiology & Behavior. 89: 687-91. PMID 16979194 DOI: 10.1016/j.physbeh.2006.08.008  1
2006 McNamara RK, Ostrander M, Abplanalp W, Richtand NM, Benoit SC, Clegg DJ. Modulation of phosphoinositide-protein kinase C signal transduction by omega-3 fatty acids: implications for the pathophysiology and treatment of recurrent neuropsychiatric illness. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 75: 237-57. PMID 16935483 DOI: 10.1016/j.plefa.2006.07.009  1
2006 Clegg DJ, Brown LM, Woods SC, Benoit SC. Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes. 55: 978-87. PMID 16567519 DOI: 10.2337/diabetes.55.04.06.db05-1339  1
2006 Reizes O, Clegg DJ, Strader AD, Benoit SC. A role for syndecan-3 in the melanocortin regulation of energy balance. Peptides. 27: 274-80. PMID 16289473 DOI: 10.1016/j.peptides.2005.02.030  1
2006 Gotoh K, Liu M, Benoit SC, Clegg DJ, Davidson WS, D'Alessio D, Seeley RJ, Tso P, Woods SC. Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R202-7. PMID 16166201 DOI: 10.1152/ajpregu.00502.2005  1
2006 Woods SC, Benoit SC, Clegg DJ. The brain-gut-islet connection Diabetes. 55: S114-S121. DOI: 10.2337/db06-S015  1
2005 Reed JA, Clegg DJ, Smith KB, Tolod-Richer EG, Matter EK, Picard LS, Seeley RJ. GM-CSF action in the CNS decreases food intake and body weight. The Journal of Clinical Investigation. 115: 3035-44. PMID 16276414 DOI: 10.1172/JCI25681  1
2005 Ogawa R, Strader AD, Clegg DJ, Sakai RR, Seeley RJ, Woods SC. Chronic food restriction and reduced dietary fat: risk factors for bouts of overeating. Physiology & Behavior. 86: 578-85. PMID 16176825 DOI: 10.1016/j.physbeh.2005.08.028  1
2005 Davidson TL, Kanoski SE, Tracy AL, Walls EK, Clegg D, Benoit SC. The interoceptive cue properties of ghrelin generalize to cues produced by food deprivation. Peptides. 26: 1602-10. PMID 16112399 DOI: 10.1016/j.peptides.2005.02.014  1
2005 Otto B, Spranger J, Benoit SC, Clegg DJ, Tschöp MH. The many faces of ghrelin: new perspectives for nutrition research? The British Journal of Nutrition. 93: 765-71. PMID 16022744 DOI: 10.1079/BJN20051446  1
2005 Benoit SC, Clegg DJ, Woods SC, Seeley RJ. The role of previous exposure in the appetitive and consummatory effects of orexigenic neuropeptides. Peptides. 26: 751-7. PMID 15808905 DOI: 10.1016/j.peptides.2004.12.012  1
2005 Clegg DJ, Benoit SC, Reed JA, Woods SC, Dunn-Meynell A, Levin BE. Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 288: R981-6. PMID 15604298 DOI: 10.1152/ajpregu.00675.2004  1
2004 Woods SC, D'Alessio DA, Tso P, Rushing PA, Clegg DJ, Benoit SC, Gotoh K, Liu M, Seeley RJ. Consumption of a high-fat diet alters the homeostatic regulation of energy balance. Physiology & Behavior. 83: 573-8. PMID 15621062 DOI: 10.1016/j.physbeh.2004.07.026  1
2004 Clegg DJ, Woods SC. The physiology of obesity. Clinical Obstetrics and Gynecology. 47: 967-79; discussion 9. PMID 15596949 DOI: 10.1097/01.grf.0000135355.25879.41  1
2004 Woods SC, Benoit SC, Clegg DJ, Seeley RJ. Clinical endocrinology and metabolism. Regulation of energy homeostasis by peripheral signals. Best Practice & Research. Clinical Endocrinology & Metabolism. 18: 497-515. PMID 15533772 DOI: 10.1016/j.beem.2004.08.004  1
2004 Seeley RJ, Drazen DL, Clegg DJ. The critical role of the melanocortin system in the control of energy balance. Annual Review of Nutrition. 24: 133-49. PMID 15189116 DOI: 10.1146/annurev.nutr.24.012003.132428  1
2004 Benoit SC, Clegg DJ, Seeley RJ, Woods SC. Insulin and leptin as adiposity signals. Recent Progress in Hormone Research. 59: 267-85. PMID 14749506 DOI: 10.1210/rp.59.1.267  1
2004 Niswender KD, Clegg DJ, Morrison CD, Morton GJ, Benoit SC. The human obesity epidemic - A physiological perspective Current Medicinal Chemistry: Immunology, Endocrine and Metabolic Agents. 4: 91-104. DOI: 10.2174/1568013043357824  1
2003 Drazen DL, Wortman MD, Schwartz MW, Clegg DJ, van Dijk G, Woods SC, Seeley RJ. Adrenalectomy alters the sensitivity of the central nervous system melanocortin system. Diabetes. 52: 2928-34. PMID 14633853 DOI: 10.2337/diabetes.52.12.2928  1
2003 Woods SC, Gotoh K, Clegg DJ. Gender differences in the control of energy homeostasis. Experimental Biology and Medicine (Maywood, N.J.). 228: 1175-80. PMID 14610257  1
2003 Benoit SC, Clegg DJ, Barrera JG, Seeley RJ, Woods SC. Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII. Diabetes. 52: 2684-8. PMID 14578286 DOI: 10.2337/diabetes.52.11.2684  1
2003 Reizes O, Benoit SC, Strader AD, Clegg DJ, Akunuru S, Seeley RJ. Syndecan-3 modulates food intake by interacting with the melanocortin/AgRP pathway. Annals of the New York Academy of Sciences. 994: 66-73. PMID 12851299  1
2003 Clegg DJ, Benoit SC, Air EL, Jackman A, Tso P, D'Alessio D, Woods SC, Seeley RJ. Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII. Endocrinology. 144: 2941-6. PMID 12810549 DOI: 10.1210/en.2002-0218  1
2003 Wortman MD, Clegg DJ, D'Alessio D, Woods SC, Seeley RJ. C75 inhibits food intake by increasing CNS glucose metabolism. Nature Medicine. 9: 483-5. PMID 12724740 DOI: 10.1038/nm0503-483  1
2003 Benoit SC, McQuade JA, Clegg DJ, Xu M, Rushing PA, Woods SC, Seeley RJ. Altered feeding responses in mice with targeted disruption of the dopamine-3 receptor gene. Behavioral Neuroscience. 117: 46-54. PMID 12619907 DOI: 10.1037/0735-7044.117.1.46  1
2003 Clegg DJ, Riedy CA, Smith KA, Benoit SC, Woods SC. Differential sensitivity to central leptin and insulin in male and female rats. Diabetes. 52: 682-7. PMID 12606509 DOI: 10.2337/diabetes.52.3.682  1
2003 Clegg DJ, Edwards GL, Martin RJ. Central insulin potentiates eating elicited by 2-deoxy-D-glucose. Physiology & Behavior. 78: 331-6. PMID 12576132 DOI: 10.1016/S0031-9384(02)01000-4  1
2003 Clegg DJ, Air EL, Benoit SC, Sakai RS, Seeley RJ, Woods SC. Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 284: R494-9. PMID 12557891  1
2003 Niswender KD, Morrison CD, Clegg DJ, Olson R, Baskin DG, Myers MG, Seeley RJ, Schwartz MW. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes. 52: 227-31. PMID 12540590 DOI: 10.2337/diabetes.52.2.227  1
2002 Clegg DJ, Wortman MD, Benoit SC, McOsker CC, Seeley RJ. Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion. Diabetes. 51: 3196-201. PMID 12401710  1
2002 Brugman S, Clegg DJ, Woods SC, Seeley RJ. Combined blockade of both micro - and kappa-opioid receptors prevents the acute orexigenic action of Agouti-related protein. Endocrinology. 143: 4265-70. PMID 12399421 DOI: 10.1210/en.2002-220230  1
2002 Benoit SC, Air EL, Coolen LM, Strauss R, Jackman A, Clegg DJ, Seeley RJ, Woods SC. The catabolic action of insulin in the brain is mediated by melanocortins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9048-52. PMID 12388611  1
2002 Clegg DJ, Air EL, Woods SC, Seeley RJ. Eating elicited by orexin-a, but not melanin-concentrating hormone, is opioid mediated. Endocrinology. 143: 2995-3000. PMID 12130565 DOI: 10.1210/endo.143.8.8977  1
2002 Air EL, Benoit SC, Clegg DJ, Seeley RJ, Woods SC. Insulin and leptin combine additively to reduce food intake and body weight in rats. Endocrinology. 143: 2449-52. PMID 12021212 DOI: 10.1210/endo.143.6.8948  1
2002 Air EL, Benoit SC, Blake Smith KA, Clegg DJ, Woods SC. Acute third ventricular administration of insulin decreases food intake in two paradigms. Pharmacology, Biochemistry, and Behavior. 72: 423-9. PMID 11900815 DOI: 10.1016/S0091-3057(01)00780-8  1
1999 Clegg DJ, Smagin GN. The role of CRF (corticotropin releasing factor) in the causation of obesity in the obese Zucker rat Biochemical Archives. 15: 189-200.  1
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