David J. Mokler - Related publications

University of New England, Biddeford, ME, United States 
Limbic system, serotonin
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Li D, Park S, Lee K, Jang DS, Kim SK. 5-HT receptors mediate the analgesic effect of rosavin in a mouse model of oxaliplatin-induced peripheral neuropathic pain. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 25: 489-494. PMID 34448466 DOI: 10.4196/kjpp.2021.25.5.489   
2021 Wu Y, Wu J, Lin Z, Wang Q, Li Y, Wang A, Shan X, Liu J. Administration of a Probiotic Mixture Ameliorates Cisplatin-Induced Mucositis and Pica by Regulating 5-HT in Rats. Journal of Immunology Research. 2021: 9321196. PMID 34568500 DOI: 10.1155/2021/9321196   
2021 Madden JT, Reyna NC, Goranson EV, Gonzalez TA, Zavala AR, Pentkowski NS. Blocking serotonin 2A (5-HT) receptors attenuates the acquisition of methamphetamine-induced conditioned place preference in adult female rats. Behavioural Brain Research. 415: 113521. PMID 34391796 DOI: 10.1016/j.bbr.2021.113521   
2021 Gu D, Zhou S, Yao L, Tan Y, Chi X, Shi D, Guo S, Liu C. Effects of ShenLing BaiZhu San Supplementation on Gut Microbiota and Oxidative Stress in Rats with Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine : Ecam. 2021: 3960989. PMID 34630607 DOI: 10.1155/2021/3960989   
2021 Denis M, Dupas T, Persello A, Dontaine J, Bultot L, Betus C, Pelé T, Dhot J, Erraud A, Maillard A, Montnach J, Leroux AA, Bigot-Corbel E, Vertommen D, Rivière M, et al. An -GlcNAcylomic Approach Reveals ACLY as a Potential Target in Sepsis in the Young Rat. International Journal of Molecular Sciences. 22. PMID 34502162 DOI: 10.3390/ijms22179236   
2021 Wang W, Zhang X. Antihypertensive Effect of Galegine from in Rats. Molecules (Basel, Switzerland). 26. PMID 34443434 DOI: 10.3390/molecules26164830   
2021 Miller L, Hébert CD, Grimes SD, Toomey JS, Oh JY, Rose JJ, Patel RP. Safety and toxicology assessment of sodium nitrite administered by intramuscular injection. Toxicology and Applied Pharmacology. 115702. PMID 34464673 DOI: 10.1016/j.taap.2021.115702   
2021 Salman T, Afroz R, Nawaz S, Mahmood K, Haleem DJ, Zarina S. Differential effects of memory enhancing and impairing doses of methylphenidate on serotonin metabolism and 5-HT1A, GABA, glutamate receptor expression in the rat prefrontal cortex. Biochimie. 191: 51-61. PMID 34454977 DOI: 10.1016/j.biochi.2021.08.009   
2021 Oyewopo AO, Adeleke O, Johnson O, Akingbade A, Olaniyi KS, Areola ED, Tokunbo O. Regulatory effects of quercetin on testicular histopathology induced by cyanide in Wistar rats. Heliyon. 7: e07662. PMID 34401560 DOI: 10.1016/j.heliyon.2021.e07662   
2021 Yeh JN, Sung PH, Chiang JY, Sheu JJ, Huang CR, Chu YC, Chua S, Yip HK. Early treatment with combination of SS31 and entresto effectively preserved the heart function in doxorubicin-induced dilated cardiomyopathic rat. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 141: 111886. PMID 34426177 DOI: 10.1016/j.biopha.2021.111886   
2021 Techera Antunes FT, de Souza AH, Caminski ES, Greggio S, Venturin GT, da Costa JC, Taffarel M, Rebelo IN, Gomez MV, Correa DS, Vilanova FN, Regner AP, Dallegrave E. Neuroprotective effects of the CTK 01512-2 toxin against neurotoxicity induced by 3-nitropropionic acid in rats. Neurotoxicology. PMID 34478769 DOI: 10.1016/j.neuro.2021.08.016   
2021 Sun L. Low-dose cyclooxygenase-2 (COX-2) inhibitor celecoxib plays a protective role in the rat model of neonatal necrotizing enterocolitis. Bioengineered. 12: 7234-7245. PMID 34546832 DOI: 10.1080/21655979.2021.1980646   
2021 Park SH, Lim JO, Kim WI, Park SW, Lee SJ, Shin IS, Moon C, Kim JH, Heo JD, Kim JC. Subchronic Toxicity Evaluation of Aluminum Oxide Nanoparticles in Rats Following 28-Day Repeated Oral Administration. Biological Trace Element Research. PMID 34535882 DOI: 10.1007/s12011-021-02926-5   
2021 Li X, Yeh CY, Bello NT. High-fat diet attenuates morphine withdrawal effects on sensory-evoked locus coeruleus norepinephrine neural activity in male obese rats. Nutritional Neuroscience. 1-10. PMID 34467832 DOI: 10.1080/1028415X.2021.1968103   
2021 Hassan EB, Doyle N, Bienvenu JG, Stent A, Guillemin GJ, Duque G. Evaluating the toxicity of escalating dose of oral picolinic acid in Sprague-Dawley rats. Toxicology. 152960. PMID 34555453 DOI: 10.1016/j.tox.2021.152960   
2021 Swann-Thomsen HE, Mendez-Gallardo V, Kollmeyer LR, Hunter K, Brumley MR. A preliminary investigation of high retinoic acid exposure during fetal development on behavioral competency and litter characteristics in newborn rats. Brain and Behavior. e2253. PMID 34473418 DOI: 10.1002/brb3.2253   
2021 AbdRabou MA, Mehany ABM, Farrag IM, Belal A, Abdelzaher OF, El-Sharkawy A, Abd El-Azez AM, El-Sharkawy SM, Al Badawi MH. Therapeutic Effect of Murine Bone Marrow-Derived Mesenchymal Stromal/Stem Cells and Human Placental Extract on Testicular Toxicity Resulting from Doxorubicin in Rats. Biomed Research International. 2021: 9979670. PMID 34409109 DOI: 10.1155/2021/9979670   
2021 Salemi LA, Sahlstrom AL, Lim SY, Johnson PN, Dannaway D, Miller JL. Evaluation of the Use of Caffeine Citrate Maintenance Doses >5 mg/kg/day in Preterm Neonates for Apnea of Prematurity. The Journal of Pediatric Pharmacology and Therapeutics : Jppt : the Official Journal of Ppag. 26: 608-614. PMID 34421411 DOI: 10.5863/1551-6776-26.6.608   
2021 Ekor M, Owusu Agyei PE, Obese E, Biney RP, Henneh IT, Antwi-Adjei M, Yahaya ES, Amoakohene G, Akakpo PK. Celecoxib exhibits therapeutic potential in experimental model of hyperlipidaemia. Plos One. 16: e0247735. PMID 34403420 DOI: 10.1371/journal.pone.0247735   
2021 Ayoub SM, Piscitelli F, Silvestri C, Limebeer CL, Rock EM, Smoum R, Farag M, de Almeida H, Sullivan MT, Lacroix S, Boubertakh B, Nallabelli N, Lichtman AH, Leri F, Mechoulam R, et al. Spontaneous and Naloxone-Precipitated Withdrawal Behaviors From Chronic Opiates are Accompanied by Changes in -Oleoylglycine and -Oleoylalanine Levels in the Brain and Ameliorated by Treatment With These Mediators. Frontiers in Pharmacology. 12: 706703. PMID 34603019 DOI: 10.3389/fphar.2021.706703   
2021 Zare Z, Zarbakhsh S, Mashhadban S, Moradgholi A, Mohammadi M. Apoptosis is involved in paraoxon-induced histological changes in rat cerebellum. Drug and Chemical Toxicology. 1-7. PMID 34412520 DOI: 10.1080/01480545.2021.1966243   
2021 Refaie MMM, Shehata S, Ibrahim RA, Bayoumi AMA, Abdel-Gaber SA. Dose-Dependent Cardioprotective Effect of Hemin in Doxorubicin-Induced Cardiotoxicity Via Nrf-2/HO-1 and TLR-5/NF-κB/TNF-α Signaling Pathways. Cardiovascular Toxicology. PMID 34510376 DOI: 10.1007/s12012-021-09694-7   
2021 Murugan S, Solanki H, Purusothaman D, Bethapudi B, Ravalji M, Mundkinajeddu D. Safety Evaluation of Standardized Extract of (NR-INF-02): A 90-Day Subchronic Oral Toxicity Study in Rats. Biomed Research International. 2021: 6671853. PMID 34337042 DOI: 10.1155/2021/6671853   
2021 Zhu JP, Gong H, Labreche F, Kou XH, Wu CE, Fan GJ, Li TT, Wang JH. In vivo toxicity assessment of 4'-O-methylpyridoxine from Ginkgo biloba seeds: growth, hematology, metabolism, and oxidative parameters. Toxicon : Official Journal of the International Society On Toxinology. PMID 34425140 DOI: 10.1016/j.toxicon.2021.08.015   
2021 Harun NH, Rasdi NA, Salleh RM, Safuan S, Ahmad WANW, Fuad WEM. Subacute Toxicity Evaluation of Methanolic Extract of in Rats. Tropical Life Sciences Research. 32: 65-81. PMID 34367515 DOI: 10.21315/tlsr2021.32.2.5   
2021 Xu Y, Lu J, Yao B, Zhang Y, Huang S, Liu J, Zhang Y, Guo Y, Wang X. P-glycoprotein mediates the pharmacokinetic interaction of olanzapine with fluoxetine in rats. Toxicology and Applied Pharmacology. 115735. PMID 34610281 DOI: 10.1016/j.taap.2021.115735   
2021 Fonseca KM, Macda RodriguesCosta D, da Silva VF, de Carvalho JL, Oliveira AP, de Melo Sousa FB, Lopes ALF, da Silva Martins C, de Sousa Chaves L, Nicolau LAD, Cerqueira GS, Medeiros JVR. Anti-inflammatory effect of L-cysteine (a semi-essential amino acid) on 5-FU-induced oral mucositis in hamsters. Amino Acids. PMID 34410507 DOI: 10.1007/s00726-021-03062-z   
2021 Reyes-Cuapio E, Coronado-Álvarez A, Quiroga C, Alcaraz-Silva J, Ruíz-Ruíz JC, Imperatori C, Murillo-Rodríguez E. Juvenile cannabidiol chronic treatments produce robust changes in metabolic markers in adult male Wistar rats. European Journal of Pharmacology. 174463. PMID 34478689 DOI: 10.1016/j.ejphar.2021.174463   
2021 Maliyakkal N, Saleem U, Anwar F, Shah MA, Ahmad B, Umer F, Almoyad MAA, Parambi DGT, Beeran AA, Nath LR, Aleya L, Mathew B. Ameliorative effect of ethoxylated chalcone-based MAO-B inhibitor on behavioural predictors of haloperidol-induced Parkinsonism in mice: evidence of its antioxidative role against Parkinson's diseases. Environmental Science and Pollution Research International. PMID 34476688 DOI: 10.1007/s11356-021-15955-3   
2021 Sabe M, Zhao N, Crippa A, Kaiser S. Antipsychotics for negative and positive symptoms of schizophrenia: dose-response meta-analysis of randomized controlled acute phase trials. Npj Schizophrenia. 7: 43. PMID 34518532 DOI: 10.1038/s41537-021-00171-2   
2021 Bilal M, Ahmad S, Rehman T, Ghauri AO, Khalid S, Abbasi WM, Zakki SA. Anti-Hyperuricemic and Uricosuric Potential of in Oxonate-Induced Hyperuricemic Rats. Dose-Response : a Publication of International Hormesis Society. 19: 15593258211040329. PMID 34483784 DOI: 10.1177/15593258211040329   
2021 Moretti RL, Dias EN, Kiel SG, Augusto MCM, Rodrigues PS, Sampaio ACS, Medeiros LS, Martins MFM, Suffredini IB, Cardoso CV, Bondan EF. Behavioral and morphological effects of resveratrol and curcumin in rats submitted to doxorubicin-induced cognitive impairment. Research in Veterinary Science. 140: 242-250. PMID 34536813 DOI: 10.1016/j.rvsc.2021.09.009   
2021 Majeed KA, Yousaf MS, Tahir MS, Khan AR, Khan S, Saeed AA, Rehman H. Effects of Subacute Exposure of Dibutyl Phthalate on the Homeostatic Model Assessment, Thyroid Function, and Redox Status in Rats. Biomed Research International. 2021: 5521516. PMID 34395617 DOI: 10.1155/2021/5521516   
2021 Engevik M, Ruan W, Visuthranukul C, Shi Z, Engevik KA, Engevik AC, Fultz R, Schady DA, Spinler JK, Versalovic J. ATCC 6475 metabolites upregulate the serotonin transporter in the intestinal epithelium. Beneficial Microbes. 1-18. PMID 34550056 DOI: 10.3920/BM2020.0216   
2021 Alhazza IM, Ebaid H, Omar MS, Hassan I, Habila MA, Al-Tamimi J, Sheikh M. Supplementation with selenium nanoparticles alleviates diabetic nephropathy during pregnancy in the diabetic female rats. Environmental Science and Pollution Research International. PMID 34420167 DOI: 10.1007/s11356-021-15905-z   
2021 Tso KH, Lumsangkul C, Cheng MC, Ju JC, Fan YK, Chiang HI. Differential Effects of Green Tea Powders on the Protection of Brown Tsaiya and Kaiya Ducklings against Trichothecene T-2 Toxin Toxicity. Animals : An Open Access Journal From Mdpi. 11. PMID 34573507 DOI: 10.3390/ani11092541   
2021 Ramos KA, James IE, Skobieranda F, Soergel DG, Ruff D, Fossler MJ. Two-Part Phase 1 Multiple-Ascending-Dose Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of TRV734 in Healthy Adults. Clinical Pharmacology in Drug Development. PMID 34480428 DOI: 10.1002/cpdd.1016   
2021 Hemmer S, Wagmann L, Meyer MR. Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose. Archives of Toxicology. PMID 34414480 DOI: 10.1007/s00204-021-03135-8   
2021 Sandamali JAN, Hewawasam RP, Jayatilaka KAPW, Mudduwa LKB. Blume (Ceylon cinnamon) bark extract attenuates doxorubicin induced cardiotoxicity in Wistar rats. Saudi Pharmaceutical Journal : Spj : the Official Publication of the Saudi Pharmaceutical Society. 29: 820-832. PMID 34408544 DOI: 10.1016/j.jsps.2021.06.004   
2021 Wang P, Gao X, Liang M, Fang Y, Jia J, Tian J, Li Z, Qin X. Dose-Effect/Toxicity of Bupleuri Radix on Chronic Unpredictable Mild Stress and Normal Rats Based on Liver Metabolomics. Frontiers in Pharmacology. 12: 627451. PMID 34557088 DOI: 10.3389/fphar.2021.627451   
2021 Latif K, Khan AU, Izhar Ul Haque M, Naeem K. Bergapten Attenuates Nitroglycerin-Induced Migraine Headaches through Inhibition of Oxidative Stress and Inflammatory Mediators. Acs Chemical Neuroscience. PMID 34455773 DOI: 10.1021/acschemneuro.1c00146   
2021 Bin Jardan YA, Ahad A, Raish M, Ahmad A, Alam MA, Al-Mohizea AM, Al-Jenoobi FI. Assessment of glibenclamide pharmacokinetics in poloxamer 407-induced hyperlipidemic rats. Saudi Pharmaceutical Journal : Spj : the Official Publication of the Saudi Pharmaceutical Society. 29: 719-723. PMID 34400867 DOI: 10.1016/j.jsps.2021.05.002   
2021 Bradosty SW, Hamad SW, Agha NFS, Shaikh FK, Qadir Nanakali NM, Aziz PY, Salehen N, Suzergoz F, Abdulla MA. In vivo hepatoprotective effect of Morinda elliptica stem extract against liver fibrosis induced by thioacetamide. Environmental Toxicology. PMID 34436826 DOI: 10.1002/tox.23353   
2021 Dong P, Xia L, Hu L, Yang K, Wang H, Ye P. Runjing Decoction alleviated cyclophosphamide-induced oligoasthenospermia rats by inhibiting cell apoptosis via RXFP1/AKT/FOXO1 pathway. Andrologia. e14216. PMID 34396564 DOI: 10.1111/and.14216   
2021 Dehpour AR, Yousefi-Manesh H, Sheibani M, Sadeghi MA, Hemmati S, Noori T, Shirooie S. Evaluation of Anti-inflammatory and Antioxidant Effects of Sumatriptan on Carbon Tetrachloride-induced Hepatotoxicity in Rats. Drug Research. PMID 34500479 DOI: 10.1055/a-1589-5395   
2021 Hwang SJ, Wang JH, Lee JS, Lee HD, Choi TJ, Choi SH, Son CG. , a Standardized Herbal Formula, Enhances Gastric Emptying via Modulation of the Ghrelin Pathway in a Loperamide-induced Functional Dyspepsia Mouse Model. Frontiers in Pharmacology. 12: 753153. PMID 34630123 DOI: 10.3389/fphar.2021.753153   
2021 Manzar N, Khan SA, Fatima N, Nisa MU, Ahmad MH, Afzal MI, Saeed HFU, Imran M, Anjum FM, Arshad MS. Exploring the prophylactic role of soy isoflavones against polycystic ovarian syndrome. Food Science & Nutrition. 9: 4738-4744. PMID 34531987 DOI: 10.1002/fsn3.2322   
2021 Jolayemi KO, Mamman M, Sani D, Okoronkwo MO, Udechukwu CC, Orakpoghenor O. Comparative effects of artemether and in combination with diminazene aceturate in the treatment of experimental infection in rats. Journal of Parasitic Diseases : Official Organ of the Indian Society For Parasitology. 45: 673-682. PMID 34475648 DOI: 10.1007/s12639-021-01350-9   
2021 Oyovwi MO, Ben-Azu B, Edesiri TP, Victor E, Rotu RA, Ozegbe QEB, Nwangwa EK, Atuadu V, Adebayo OG. Kolaviron abates busulfan-induced episodic memory deficit and testicular dysfunction in rats: The implications for neuroendopathobiological changes during chemotherapy. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 142: 112022. PMID 34411912 DOI: 10.1016/j.biopha.2021.112022   
2021 Hoffman EG, Jahngiriesmaili M, Mandel ER, Greenberg C, Aiken J, D'Souza NC, Pasieka A, Teich T, Chan O, Liggins R, Riddell MC. Somatostatin Receptor Antagonism Reverses Glucagon Counterregulatory Failure in Recurrently Hypoglycemic Male Rats. Endocrinology. PMID 34477204 DOI: 10.1210/endocr/bqab189