| Year |
Citation |
Score |
| 2020 |
Cianferoni D, Radusky LG, Head SA, Serrano L, Delgado J. ProteinFishing: A protein complex generator within the ModelX toolsuite. Bioinformatics (Oxford, England). PMID 32437555 DOI: 10.1093/Bioinformatics/Btaa533 |
0.391 |
|
| 2020 |
Kennedy SA, Jarboui MA, Srihari S, Raso C, Bryan K, Dernayka L, Charitou T, Bernal-Llinares M, Herrera-Montavez C, Krstic A, Matallanas D, Kotlyar M, Jurisica I, Curak J, Wong V, ... ... Serrano L, et al. Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS. Nature Communications. 11: 499. PMID 31980649 DOI: 10.1038/S41467-019-14224-9 |
0.336 |
|
| 2019 |
Delgado Blanco J, Radusky LG, Cianferoni D, Serrano L. Protein-assisted RNA fragment docking (RnaX) for modeling RNA-protein interactions using ModelX. Proceedings of the National Academy of Sciences of the United States of America. PMID 31732673 DOI: 10.1073/Pnas.1910999116 |
0.352 |
|
| 2018 |
Radusky L, Modenutti C, Delgado J, Bustamante JP, Vishnopolska S, Kiel C, Serrano L, Marti M, Turjanski A. VarQ: A Tool for the Structural and Functional Analysis of Human Protein Variants. Frontiers in Genetics. 9: 620. PMID 30574164 DOI: 10.3389/Fgene.2018.00620 |
0.382 |
|
| 2018 |
Yang JS, Garriga-Canut M, Link N, Carolis C, Broadbent K, Beltran-Sastre V, Serrano L, Maurer SP. rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions. Nature Communications. 9: 3747. PMID 30217970 DOI: 10.1038/S41467-018-06128-X |
0.382 |
|
| 2018 |
Besray Unal E, Kiel C, Benisty H, Campbell A, Pickering K, Blüthgen N, Sansom OJ, Serrano L. Systems level expression correlation of Ras GTPase regulators. Cell Communication and Signaling : Ccs. 16: 46. PMID 30111366 DOI: 10.1186/S12964-018-0256-8 |
0.325 |
|
| 2018 |
Blanco JD, Radusky L, Climente-González H, Serrano L. FoldX accurate structural protein-DNA binding prediction using PADA1 (Protein Assisted DNA Assembly 1). Nucleic Acids Research. PMID 29608705 DOI: 10.1093/Nar/Gky228 |
0.361 |
|
| 2017 |
Suay-Corredera C, Herrero-Galán E, Velázquez-Carreras D, Urrutia-Irazábal Í, García-Giustiniani D, Delgado J, Serrano L, García-Pavía P, Monserrat L, Alegre-Cebollada J. Nanomechanical Phenotypes in Hypertrophic Cardiomyopathy caused by Missense Mutations in Cardiac Myosin-Binding Protein C Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.907 |
0.368 |
|
| 2016 |
Chen WH, van Noort V, Lluch-Senar M, Hennrich ML, H Wodke JA, Yus E, Alibés A, Roma G, Mende DR, Pesavento C, Typas A, Gavin AC, Serrano L, Bork P. Integration of multi-omics data of a genome-reduced bacterium: Prevalence of post-transcriptional regulation and its correlation with protein abundances. Nucleic Acids Research. PMID 26773059 DOI: 10.1093/Nar/Gkw004 |
0.302 |
|
| 2015 |
Lluch-Senar M, Mancuso FM, Climente-González H, Peña-Paz MI, Sabido E, Serrano L. Rescuing discarded spectra: Full comprehensive analysis of a minimal proteome. Proteomics. PMID 26702875 DOI: 10.1002/Pmic.201500187 |
0.359 |
|
| 2015 |
Schaefer MH, Serrano L, Andrade-Navarro MA. Correcting for the study bias associated with protein-protein interaction measurements reveals differences between protein degree distributions from different cancer types. Frontiers in Genetics. 6: 260. PMID 26300911 DOI: 10.3389/Fgene.2015.00260 |
0.387 |
|
| 2015 |
Verschueren E, Spiess M, Gkourtsa A, Avula T, Landgraf C, Mancilla VT, Huber A, Volkmer R, Winsor B, Serrano L, Hochstenbach F, Distel B. Evolution of the SH3 Domain Specificity Landscape in Yeasts. Plos One. 10: e0129229. PMID 26068101 DOI: 10.1371/Journal.Pone.0129229 |
0.367 |
|
| 2015 |
Toufighi K, Yang JS, Luis NM, Aznar Benitah S, Lehner B, Serrano L, Kiel C. Dissecting the calcium-induced differentiation of human primary keratinocytes stem cells by integrative and structural network analyses. Plos Computational Biology. 11: e1004256. PMID 25946651 DOI: 10.1371/Journal.Pcbi.1004256 |
0.375 |
|
| 2015 |
Trussart M, Serra F, Baù D, Junier I, Serrano L, Marti-Renom MA. Assessing the limits of restraint-based 3D modeling of genomes and genomic domains. Nucleic Acids Research. 43: 3465-77. PMID 25800747 DOI: 10.1093/Nar/Gkv221 |
0.303 |
|
| 2015 |
Lluch-Senar M, Delgado J, Chen WH, Lloréns-Rico V, O'Reilly FJ, Wodke JA, Unal EB, Yus E, Martínez S, Nichols RJ, Ferrar T, Vivancos A, Schmeisky A, Stülke J, van Noort V, ... ... Serrano L, et al. Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium. Molecular Systems Biology. 11: 780. PMID 25609650 DOI: 10.15252/Msb.20145558 |
0.318 |
|
| 2015 |
Wodke JA, Alibés A, Cozzuto L, Hermoso A, Yus E, Lluch-Senar M, Serrano L, Roma G. MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae. Nucleic Acids Research. 43: D618-23. PMID 25378328 DOI: 10.1093/Nar/Gku1105 |
0.307 |
|
| 2015 |
Lluch-Senar M, Delgado J, Chen WH, Lloréns-Rico V, O'Reilly FJ, Wodke JAH, Unal EB, Yus E, Martínez S, Nichols RJ, Ferrar T, Vivancos A, Schmeisky A, Stülke J, Van Noort V, ... ... Serrano L, et al. Defining a minimal cell: Essentiality of small ORFs and ncRNAs in a genome-reduced bacterium Molecular Systems Biology. 11. DOI: 10.15252/msb.20145558 |
0.574 |
|
| 2014 |
Yang JS, Sabidó E, Serrano L, Kiel C. TAPAS: tools to assist the targeted protein quantification of human alternative splice variants. Bioinformatics (Oxford, England). 30: 2989-90. PMID 24996896 DOI: 10.1093/Bioinformatics/Btu428 |
0.358 |
|
| 2014 |
Schaefer MH, Yang JS, Serrano L, Kiel C. Protein conservation and variation suggest mechanisms of cell type-specific modulation of signaling pathways. Plos Computational Biology. 10: e1003659. PMID 24922536 DOI: 10.1371/Journal.Pcbi.1003659 |
0.359 |
|
| 2014 |
Kiel C, Serrano L. Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations. Molecular Systems Biology. 10: 727. PMID 24803665 DOI: 10.1002/Msb.20145092 |
0.335 |
|
| 2014 |
Hasenhindl C, Lai B, Delgado J, Traxlmayr MW, Stadlmayr G, Rüker F, Serrano L, Oostenbrink C, Obinger C. Creating stable stem regions for loop elongation in Fcabs - insights from combining yeast surface display, in silico loop reconstruction and molecular dynamics simulations. Biochimica Et Biophysica Acta. 1844: 1530-40. PMID 24792385 DOI: 10.1016/J.Bbapap.2014.04.020 |
0.376 |
|
| 2014 |
Kiel C, Ebhardt HA, Burnier J, Portugal C, Sabidó E, Zimmermann T, Aebersold R, Serrano L. Quantification of ErbB network proteins in three cell types using complementary approaches identifies cell-general and cell-type-specific signaling proteins. Journal of Proteome Research. 13: 300-13. PMID 24313378 DOI: 10.1021/Pr400878X |
0.358 |
|
| 2013 |
Kiel C, Verschueren E, Yang JS, Serrano L. Integration of protein abundance and structure data reveals competition in the ErbB signaling network. Science Signaling. 6: ra109. PMID 24345680 DOI: 10.1126/Scisignal.2004560 |
0.425 |
|
| 2013 |
Grünberg R, Burnier JV, Ferrar T, Beltran-Sastre V, Stricher F, van der Sloot AM, Garcia-Olivas R, Mallabiabarrena A, Sanjuan X, Zimmermann T, Serrano L. Engineering of weak helper interactions for high-efficiency FRET probes. Nature Methods. 10: 1021-7. PMID 23995386 DOI: 10.1038/Nmeth.2625 |
0.356 |
|
| 2013 |
Dos Santos HG, Abia D, Janowski R, Mortuza G, Bertero MG, Boutin M, Guarín N, Méndez-Giraldez R, Nuñez A, Pedrero JG, Redondo P, Sanz M, Speroni S, Teichert F, Bruix M, ... ... Serrano L, et al. Structure and non-structure of centrosomal proteins. Plos One. 8: e62633. PMID 23671615 DOI: 10.1371/Journal.Pone.0062633 |
0.426 |
|
| 2013 |
Verschueren E, Vanhee P, Rousseau F, Schymkowitz J, Serrano L. Protein-peptide complex prediction through fragment interaction patterns. Structure (London, England : 1993). 21: 789-97. PMID 23583037 DOI: 10.1016/J.Str.2013.02.023 |
0.443 |
|
| 2012 |
Kiel C, Serrano L. Structural data in synthetic biology approaches for studying general design principles of cellular signaling networks. Structure (London, England : 1993). 20: 1806-13. PMID 23141693 DOI: 10.1016/J.Str.2012.10.002 |
0.361 |
|
| 2012 |
Yang JS, Campagna A, Delgado J, Vanhee P, Serrano L, Kiel C. SAPIN: a framework for the structural analysis of protein interaction networks. Bioinformatics (Oxford, England). 28: 2998-9. PMID 22954630 DOI: 10.1093/Bioinformatics/Bts539 |
0.401 |
|
| 2012 |
Magis C, van der Sloot AM, Serrano L, Notredame C. An improved understanding of TNFL/TNFR interactions using structure-based classifications. Trends in Biochemical Sciences. 37: 353-63. PMID 22789664 DOI: 10.1016/J.Tibs.2012.06.002 |
0.333 |
|
| 2012 |
van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, et al. Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. Molecular Systems Biology. 8: 571. PMID 22373819 DOI: 10.1038/Msb.2012.4 |
0.37 |
|
| 2012 |
Lamond AI, Uhlen M, Horning S, Makarov A, Robinson CV, Serrano L, Hartl FU, Baumeister W, Werenskiold AK, Andersen JS, Vorm O, Linial M, Aebersold R, Mann M. Advancing cell biology through proteomics in space and time (PROSPECTS). Molecular & Cellular Proteomics : McP. 11: O112.017731. PMID 22311636 DOI: 10.1074/Mcp.O112.017731 |
0.345 |
|
| 2011 |
Kiel C, Vogt A, Campagna A, Chatr-aryamontri A, Swiatek-de Lange M, Beer M, Bolz S, Mack AF, Kinkl N, Cesareni G, Serrano L, Ueffing M. Structural and functional protein network analyses predict novel signaling functions for rhodopsin. Molecular Systems Biology. 7: 551. PMID 22108793 DOI: 10.1038/Msb.2011.83 |
0.381 |
|
| 2011 |
Maier T, Schmidt A, Güell M, Kühner S, Gavin AC, Aebersold R, Serrano L. Quantification of mRNA and protein and integration with protein turnover in a bacterium. Molecular Systems Biology. 7: 511. PMID 21772259 DOI: 10.1038/Msb.2011.38 |
0.377 |
|
| 2011 |
Verschueren E, Vanhee P, van der Sloot AM, Serrano L, Rousseau F, Schymkowitz J. Protein design with fragment databases. Current Opinion in Structural Biology. 21: 452-9. PMID 21684149 DOI: 10.1016/J.Sbi.2011.05.002 |
0.413 |
|
| 2011 |
Nadra AD, Serrano L, Alibés A. DNA-binding specificity prediction with FoldX. Methods in Enzymology. 498: 3-18. PMID 21601671 DOI: 10.1016/B978-0-12-385120-8.00001-2 |
0.33 |
|
| 2011 |
Gfeller D, Butty F, Wierzbicka M, Verschueren E, Vanhee P, Huang H, Ernst A, Dar N, Stagljar I, Serrano L, Sidhu SS, Bader GD, Kim PM. The multiple-specificity landscape of modular peptide recognition domains. Molecular Systems Biology. 7: 484. PMID 21525870 DOI: 10.1038/Msb.2011.18 |
0.458 |
|
| 2011 |
Vanhee P, van der Sloot AM, Verschueren E, Serrano L, Rousseau F, Schymkowitz J. Computational design of peptide ligands. Trends in Biotechnology. 29: 231-9. PMID 21316780 DOI: 10.1016/J.Tibtech.2011.01.004 |
0.376 |
|
| 2011 |
Rakoczy EP, Kiel C, McKeone R, Stricher F, Serrano L. Analysis of disease-linked rhodopsin mutations based on structure, function, and protein stability calculations. Journal of Molecular Biology. 405: 584-606. PMID 21094163 DOI: 10.1016/J.Jmb.2010.11.003 |
0.338 |
|
| 2011 |
Muñoz IG, Prieto J, Subramanian S, Coloma J, Redondo P, Villate M, Merino N, Marenchino M, D'Abramo M, Gervasio FL, Grizot S, Daboussi F, Smith J, Chion-Sotinel I, Pâques F, ... ... Serrano L, et al. Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus. Nucleic Acids Research. 39: 729-43. PMID 20846960 DOI: 10.1093/Nar/Gkq801 |
0.309 |
|
| 2010 |
Alibés A, Serrano L, Nadra AD. Structure-based DNA-binding prediction and design. Methods in Molecular Biology (Clifton, N.J.). 649: 77-88. PMID 20680828 DOI: 10.1007/978-1-60761-753-2_4 |
0.37 |
|
| 2010 |
Raineri E, Ribeca P, Serrano L, Maier T. A more precise characterization of chaperonin substrates. Bioinformatics (Oxford, England). 26: 1685-9. PMID 20519287 DOI: 10.1093/Bioinformatics/Btq287 |
0.359 |
|
| 2010 |
Magis C, Stricher F, van der Sloot AM, Serrano L, Notredame C. T-RMSD: a fine-grained, structure-based classification method and its application to the functional characterization of TNF receptors. Journal of Molecular Biology. 400: 605-17. PMID 20471393 DOI: 10.1016/J.Jmb.2010.05.012 |
0.32 |
|
| 2010 |
Grünberg R, Serrano L. Strategies for protein synthetic biology. Nucleic Acids Research. 38: 2663-75. PMID 20385577 DOI: 10.1093/Nar/Gkq139 |
0.411 |
|
| 2010 |
Grünberg R, Ferrar TS, van der Sloot AM, Constante M, Serrano L. Building blocks for protein interaction devices. Nucleic Acids Research. 38: 2645-62. PMID 20215443 DOI: 10.1093/Nar/Gkq152 |
0.413 |
|
| 2010 |
Maurer-Stroh S, Debulpaep M, Kuemmerer N, Lopez de la Paz M, Martins IC, Reumers J, Morris KL, Copland A, Serpell L, Serrano L, Schymkowitz JW, Rousseau F. Exploring the sequence determinants of amyloid structure using position-specific scoring matrices. Nature Methods. 7: 237-42. PMID 20154676 DOI: 10.1038/Nmeth.1432 |
0.346 |
|
| 2010 |
Sánchez-Hidalgo M, Fernández-Escamilla AM, Martínez-Bueno M, Valdivia E, Serrano L, Maqueda M. Conformational stability and activity of circular Enterocin AS-48 derivatives. Protein and Peptide Letters. 17: 708-14. PMID 19958277 DOI: 10.2174/092986610791190390 |
0.356 |
|
| 2010 |
Vanhee P, Stricher F, Baeten L, Verschueren E, Serrano L, Rousseau F, Schymkowitz J. Modeling protein-peptide interactions using protein fragments: fitting the pieces? Bmc Bioinformatics. 11: 1-2. DOI: 10.1186/1471-2105-11-S10-O1 |
0.382 |
|
| 2009 |
Kühner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castaño-Diez D, Chen WH, Devos D, Güell M, Norambuena T, ... ... Serrano L, et al. Proteome organization in a genome-reduced bacterium. Science (New York, N.Y.). 326: 1235-40. PMID 19965468 DOI: 10.1126/Science.1176343 |
0.326 |
|
| 2009 |
Maier T, Güell M, Serrano L. Correlation of mRNA and protein in complex biological samples. Febs Letters. 583: 3966-73. PMID 19850042 DOI: 10.1016/J.Febslet.2009.10.036 |
0.333 |
|
| 2009 |
Vanhee P, Stricher F, Baeten L, Verschueren E, Lenaerts T, Serrano L, Rousseau F, Schymkowitz J. Protein-peptide interactions adopt the same structural motifs as monomeric protein folds. Structure (London, England : 1993). 17: 1128-36. PMID 19679090 DOI: 10.1016/J.Str.2009.06.013 |
0.446 |
|
| 2009 |
Encinar JA, Fernandez-Ballester G, Sánchez IE, Hurtado-Gomez E, Stricher F, Beltrao P, Serrano L. ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs. Bioinformatics (Oxford, England). 25: 2418-24. PMID 19602529 DOI: 10.1093/Bioinformatics/Btp424 |
0.766 |
|
| 2009 |
Sloot AMVd, Kiel C, Serrano L, Stricher F. Protein design in biological networks: from manipulating the input to modifying the output Protein Engineering Design & Selection. 22: 537-542. PMID 19574296 DOI: 10.1093/Protein/Gzp032 |
0.373 |
|
| 2009 |
Markson G, Kiel C, Hyde R, Brown S, Charalabous P, Bremm A, Semple J, Woodsmith J, Duley S, Salehi-Ashtiani K, Vidal M, Komander D, Serrano L, Lehner P, Sanderson CM. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. Genome Research. 19: 1905-11. PMID 19549727 DOI: 10.1101/Gr.093963.109 |
0.303 |
|
| 2009 |
Fernandez-Ballester G, Beltrao P, Gonzalez JM, Song YH, Wilmanns M, Valencia A, Serrano L. Structure-based prediction of the Saccharomyces cerevisiae SH3-ligand interactions. Journal of Molecular Biology. 388: 902-16. PMID 19324052 DOI: 10.1016/J.Jmb.2009.03.038 |
0.693 |
|
| 2009 |
Petukhov M, Tatsu Y, Tamaki K, Murase S, Uekawa H, Yoshikawa S, Serrano L, Yumoto N. Design of stable alpha-helices using global sequence optimization. Journal of Peptide Science : An Official Publication of the European Peptide Society. 15: 359-65. PMID 19222027 DOI: 10.1002/Psc.1122 |
0.452 |
|
| 2009 |
Raineri E, Ribeca P, Serrano L, Maier T. Novel Determinants Describe Chaperonin Substrate Proteins Nature Precedings. DOI: 10.1038/Npre.2009.2968.2 |
0.406 |
|
| 2009 |
Raineri E, Ribeca P, Serrano L, Maier T. Evolvability of Chaperonin Substrate Proteins Nature Precedings. DOI: 10.1038/Npre.2009.2968.1 |
0.382 |
|
| 2008 |
Kiel C, Aydin D, Serrano L. Association rate constants of ras-effector interactions are evolutionarily conserved. Plos Computational Biology. 4. PMID 19096503 DOI: 10.1371/Journal.Pcbi.1000245 |
0.373 |
|
| 2008 |
Liew CW, Vockel M, Glassmeier G, Brandner JM, Fernandez-Ballester GJ, Schwarz JR, Schulz S, Buck F, Serrano L, Richter D, Kreienkamp HJ. Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions. Febs Letters. 583: 49-54. PMID 19071123 DOI: 10.1016/J.Febslet.2008.11.048 |
0.362 |
|
| 2008 |
Lenaerts T, Ferkinghoff-Borg J, Stricher F, Serrano L, Schymkowitz JW, Rousseau F. Quantifying information transfer by protein domains: analysis of the Fyn SH2 domain structure. Bmc Structural Biology. 8: 43. PMID 18842137 DOI: 10.1186/1472-6807-8-43 |
0.387 |
|
| 2008 |
Esteras-Chopo A, Morra G, Moroni E, Serrano L, Paz MLdl, Colombo G. A molecular dynamics study of the interaction of D-peptide amyloid inhibitors with their target sequence reveals a potential inhibitory pharmacophore conformation. Journal of Molecular Biology. 383: 266-280. PMID 18703072 DOI: 10.1016/J.Jmb.2008.07.076 |
0.386 |
|
| 2008 |
Baeten L, Reumers J, Tur V, Stricher F, Lenaerts T, Serrano L, Rousseau F, Schymkowitz J. Reconstruction of protein backbones from the BriX collection of canonical protein fragments. Plos Computational Biology. 4: e1000083. PMID 18483555 DOI: 10.1371/Journal.Pcbi.1000083 |
0.452 |
|
| 2008 |
Isalan M, Lemerle C, Michalodimitrakis K, Horn C, Beltrao P, Raineri E, Garriga-Canut M, Serrano L. Evolvability and hierarchy in rewired bacterial gene networks. Nature. 452: 840-5. PMID 18421347 DOI: 10.1038/Nature06847 |
0.596 |
|
| 2008 |
Sánchez IE, Beltrao P, Stricher F, Schymkowitz J, Ferkinghoff-Borg J, Rousseau F, Serrano L. Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm. Plos Computational Biology. 4: e1000052. PMID 18389064 DOI: 10.1371/Journal.Pcbi.1000052 |
0.761 |
|
| 2008 |
Sánchez-Hidalgo M, Martínez-Bueno M, Fernández-Escamilla AM, Valdivia E, Serrano L, Maqueda M. Effect of replacing glutamic residues upon the biological activity and stability of the circular enterocin AS-48. The Journal of Antimicrobial Chemotherapy. 61: 1256-65. PMID 18385141 DOI: 10.1093/Jac/Dkn126 |
0.308 |
|
| 2008 |
Kiel C, Beltrao P, Serrano L. Analyzing protein interaction networks using structural information. Annual Review of Biochemistry. 77: 415-41. PMID 18304007 DOI: 10.1146/Annurev.Biochem.77.062706.133317 |
0.68 |
|
| 2008 |
Campagna A, Serrano L, Kiel C. Shaping dots and lines: Adding modularity into protein interaction networks using structural information Febs Letters. 582: 1231-1236. PMID 18282473 DOI: 10.1016/J.Febslet.2008.02.019 |
0.379 |
|
| 2008 |
Fajardo-Sanchez E, Stricher F, Pâques F, Isalan M, Serrano L. Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences. Nucleic Acids Research. 36: 2163-2173. PMID 18276641 DOI: 10.1093/Nar/Gkn059 |
0.308 |
|
| 2007 |
Pey AL, Stricher F, Serrano L, Martinez A. Predicted Effects of Missense Mutations on Native-State Stability Account for Phenotypic Outcome in Phenylketonuria, a Paradigm of Misfolding Diseases American Journal of Human Genetics. 81: 1006-1024. PMID 17924342 DOI: 10.1086/521879 |
0.329 |
|
| 2007 |
Szczepek M, Brondani V, Büchel J, Serrano L, Segal DJ, Cathomen T. Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. Nature Biotechnology. 25: 786-93. PMID 17603476 DOI: 10.1038/Nbt1317 |
0.347 |
|
| 2007 |
Kiel C, Serrano L. Prediction of Ras-effector interactions using position energy matrices Bioinformatics. 23: 2226-2230. PMID 17599936 DOI: 10.1093/Bioinformatics/Btm336 |
0.403 |
|
| 2007 |
Beltrao P, Kiel C, Serrano L. Structures in systems biology. Current Opinion in Structural Biology. 17: 378-84. PMID 17574836 DOI: 10.1016/J.Sbi.2007.05.005 |
0.621 |
|
| 2007 |
Kiel C, Foglierini M, Kuemmerer N, Beltrao P, Serrano L. A genome-wide Ras-effector interaction network. Journal of Molecular Biology. 370: 1020-32. PMID 17544445 DOI: 10.1016/J.Jmb.2007.05.015 |
0.651 |
|
| 2007 |
Tokuriki N, Stricher F, Schymkowitz J, Serrano L, Tawfik DS. The stability effects of protein mutations appear to be universally distributed. Journal of Molecular Biology. 369: 1318-32. PMID 17482644 DOI: 10.1016/J.Jmb.2007.03.069 |
0.345 |
|
| 2007 |
Beltrao P, Serrano L. Specificity and evolvability in eukaryotic protein interaction networks. Plos Computational Biology. 3: e25. PMID 17305419 DOI: 10.1038/Npre.2007.26.1 |
0.666 |
|
| 2007 |
Kölsch V, Seher T, Fernandez-Ballester GJ, Serrano L, Leptin M. Control of Drosophila gastrulation by apical localization of adherens junctions and RhoGEF2. Science (New York, N.Y.). 315: 384-6. PMID 17234948 DOI: 10.1126/Science.1134833 |
0.307 |
|
| 2007 |
Cerdà-Costa N, Esteras-Chopo A, Avilés FX, Serrano L, Villegas V. Early kinetics of amyloid fibril formation reveals conformational reorganisation of initial aggregates. Journal of Molecular Biology. 366: 1351-63. PMID 17204287 DOI: 10.1016/J.Jmb.2006.12.007 |
0.397 |
|
| 2007 |
Beltrao P, Serrano L. Correction: Specificity and Evolvability in Eukaryotic Protein Interaction Networks Plos Computational Biology. 3: e70. DOI: 10.1371/Journal.Pcbi.0030070 |
0.606 |
|
| 2006 |
Sánchez IE, Tejero J, Gómez-Moreno C, Medina M, Serrano L. Point mutations in protein globular domains: contributions from function, stability and misfolding. Journal of Molecular Biology. 363: 422-32. PMID 16978645 DOI: 10.1016/J.Jmb.2006.08.020 |
0.64 |
|
| 2006 |
Fernández-Escamilla AM, Ventura S, Serrano L, Jiménez MA. Design and NMR conformational study of a beta-sheet peptide based on Betanova and WW domains. Protein Science : a Publication of the Protein Society. 15: 2278-89. PMID 16963647 DOI: 10.1110/Ps.062186506 |
0.38 |
|
| 2006 |
Rousseau F, Wilkinson H, Villanueva J, Serrano L, Schymkowitz JW, Itzhaki LS. Domain swapping in p13suc1 results in formation of native-like, cytotoxic aggregates. Journal of Molecular Biology. 363: 496-505. PMID 16963085 DOI: 10.1016/J.Jmb.2006.07.061 |
0.351 |
|
| 2006 |
Fernandez-Ballester G, Serrano L. Prediction of Protein–Protein Interaction Based on Structure Methods of Molecular Biology. 340: 207-234. PMID 16957339 DOI: 10.1385/1-59745-116-9:207 |
0.408 |
|
| 2006 |
Kempkens Ö, Médina E, Fernandez-Ballester G, Özüyaman S, Bivic AL, Serrano L, Knust E. Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila Crumbs for the PDZ domains of Stardust and DmPar-6 European Journal of Cell Biology. 85: 753-767. PMID 16697075 DOI: 10.1016/J.Ejcb.2006.03.003 |
0.424 |
|
| 2006 |
Musi V, Birdsall B, Fernandez-Ballester G, Guerrini R, Salvatori S, Serrano L, Pastore A. New approaches to high-throughput structure characterization of SH3 complexes: the example of Myosin-3 and Myosin-5 SH3 domains from S. cerevisiae. Protein Science : a Publication of the Protein Society. 15: 795-807. PMID 16600966 DOI: 10.1110/Ps.051785506 |
0.438 |
|
| 2006 |
Rousseau F, Schymkowitz J, Serrano L. Protein aggregation and amyloidosis: confusion of the kinds? Current Opinion in Structural Biology. 16: 118-26. PMID 16434184 DOI: 10.1016/J.Sbi.2006.01.011 |
0.354 |
|
| 2006 |
Rousseau F, Serrano L, Schymkowitz JW. How evolutionary pressure against protein aggregation shaped chaperone specificity. Journal of Molecular Biology. 355: 1037-47. PMID 16359707 DOI: 10.1016/J.Jmb.2005.11.035 |
0.399 |
|
| 2006 |
Arnould S, Chames P, Perez C, Lacroix E, Duclert A, Epinat JC, Stricher F, Petit AS, Patin A, Guillier S, Rolland S, Prieto J, Blanco FJ, Bravo J, Montoya G, ... Serrano L, et al. Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets. Journal of Molecular Biology. 355: 443-58. PMID 16310802 DOI: 10.1016/J.Jmb.2005.10.065 |
0.361 |
|
| 2006 |
Kiel C, Serrano L. The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes. Journal of Molecular Biology. 355: 821-844. PMID 16310215 DOI: 10.1016/J.Jmb.2005.10.010 |
0.407 |
|
| 2005 |
Neduva V, Linding R, Su-Angrand I, Stark A, de Masi F, Gibson TJ, Lewis J, Serrano L, Russell RB. Systematic discovery of new recognition peptides mediating protein interaction networks. Plos Biology. 3: e405. PMID 16279839 DOI: 10.1371/Journal.Pbio.0030405 |
0.43 |
|
| 2005 |
Michalodimitrakis KM, Sourjik V, Serrano L. Plasticity in amino acid sensing of the chimeric receptor Taz. Molecular Microbiology. 58: 257-66. PMID 16164563 DOI: 10.1111/J.1365-2958.2005.04821.X |
0.316 |
|
| 2005 |
Beltrao P, Serrano L. Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions. Plos Computational Biology. 1: e26. PMID 16110343 DOI: 10.1371/Journal.Pcbi.0010026 |
0.655 |
|
| 2005 |
Schymkowitz JW, Rousseau F, Martins IC, Ferkinghoff-Borg J, Stricher F, Serrano L. Prediction of water and metal binding sites and their affinities by using the Fold-X force field. Proceedings of the National Academy of Sciences of the United States of America. 102: 10147-52. PMID 16006526 DOI: 10.1073/Pnas.0501980102 |
0.304 |
|
| 2005 |
Schymkowitz J, Borg J, Stricher F, Nys R, Rousseau F, Serrano L. The FoldX web server: an online force field. Nucleic Acids Research. 33: W382-8. PMID 15980494 DOI: 10.1093/Nar/Gki387 |
0.394 |
|
| 2005 |
Bork P, Serrano L. Towards cellular systems in 4D. Cell. 121: 507-9. PMID 15907464 DOI: 10.1016/J.Cell.2005.05.001 |
0.308 |
|
| 2005 |
López de la Paz M, de Mori GM, Serrano L, Colombo G. Sequence dependence of amyloid fibril formation: insights from molecular dynamics simulations. Journal of Molecular Biology. 349: 583-96. PMID 15882870 DOI: 10.1016/J.Jmb.2005.03.081 |
0.368 |
|
| 2005 |
Kiel C, Wohlgemuth S, Rousseau F, Schymkowitz J, Ferkinghoff-Borg J, Wittinghofer F, Serrano L. Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations. Journal of Molecular Biology. 348: 759-75. PMID 15826669 DOI: 10.1016/J.Jmb.2005.02.046 |
0.327 |
|
| 2005 |
Maxwell KL, Wildes D, Zarrine-Afsar A, De Los Rios MA, Brown AG, Friel CT, Hedberg L, Horng JC, Bona D, Miller EJ, Vallée-Bélisle A, Main ER, Bemporad F, Qiu L, Teilum K, ... ... Serrano L, et al. Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Science : a Publication of the Protein Society. 14: 602-16. PMID 15689503 DOI: 10.1110/Ps.041205405 |
0.387 |
|
| 2005 |
Reumers J, Schymkowitz J, Ferkinghoff-Borg J, Stricher F, Serrano L, Rousseau F. SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs. Nucleic Acids Research. 33: D527-32. PMID 15608254 DOI: 10.1093/Nar/Gki086 |
0.322 |
|
| 2004 |
Ander M, Beltrao P, Di Ventura B, Ferkinghoff-Borg J, Foglierini M, Kaplan A, Lemerle C, Tomás-Oliveira I, Serrano L. SmartCell, a framework to simulate cellular processes that combines stochastic approximation with diffusion and localisation: analysis of simple networks Systems Biology. 1: 129-138. PMID 17052123 DOI: 10.1049/sb:20045017 |
0.554 |
|
| 2004 |
Burns DC, Flint DG, Kumita JR, Feldman HJ, Serrano L, Zhang Z, Smart OS, Woolley GA. Origins of helix-coil switching in a light-sensitive peptide. Biochemistry. 43: 15329-38. PMID 15581345 DOI: 10.1021/Bi048152K |
0.361 |
|
| 2004 |
Sloot AMvd, Mullally MM, Fernandez-Ballester G, Serrano L, Quax WJ. Stabilization of TRAIL, an all-β-sheet multimeric protein, using computational redesign Protein Engineering Design & Selection. 17: 673-680. PMID 15486023 DOI: 10.1093/Protein/Gzh079 |
0.386 |
|
| 2004 |
Fernandez-Escamilla AM, Rousseau F, Schymkowitz J, Serrano L. Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins. Nature Biotechnology. 22: 1302-6. PMID 15361882 DOI: 10.1038/Nbt1012 |
0.37 |
|
| 2004 |
Cobos ES, Pisabarro MT, Vega MC, Lacroix E, Serrano L, Ruiz-Sanz J, Martinez JC. A miniprotein scaffold used to assemble the polyproline II binding epitope recognized by SH3 domains. Journal of Molecular Biology. 342: 355-65. PMID 15313630 DOI: 10.1016/J.Jmb.2004.06.078 |
0.449 |
|
| 2004 |
Linding R, Schymkowitz J, Rousseau F, Diella F, Serrano L. A comparative study of the relationship between protein structure and beta-aggregation in globular and intrinsically disordered proteins. Journal of Molecular Biology. 342: 345-53. PMID 15313629 DOI: 10.1016/J.Jmb.2004.06.088 |
0.43 |
|
| 2004 |
Petukhov M, Rychkov G, Firsov L, Serrano L. H-bonding in protein hydration revisited. Protein Science : a Publication of the Protein Society. 13: 2120-9. PMID 15238635 DOI: 10.1110/Ps.04748404 |
0.328 |
|
| 2004 |
Kiel C, Serrano L, Herrmann C. A detailed thermodynamic analysis of ras/effector complex interfaces. Journal of Molecular Biology. 340: 1039-1058. PMID 15236966 DOI: 10.1016/J.Jmb.2004.05.050 |
0.359 |
|
| 2004 |
Ventura S, Serrano L. Designing proteins from the inside out. Proteins. 56: 1-10. PMID 15162481 DOI: 10.1002/Prot.20142 |
0.43 |
|
| 2004 |
Ventura S, Zurdo J, Narayanan S, Parreño M, Mangues R, Reif B, Chiti F, Giannoni E, Dobson CM, Aviles FX, Serrano L. Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case. Proceedings of the National Academy of Sciences of the United States of America. 101: 7258-63. PMID 15123800 DOI: 10.1073/Pnas.0308249101 |
0.44 |
|
| 2004 |
Aloy P, Böttcher B, Ceulemans H, Leutwein C, Mellwig C, Fischer S, Gavin AC, Bork P, Superti-Furga G, Serrano L, Russell RB. Structure-based assembly of protein complexes in yeast. Science (New York, N.Y.). 303: 2026-9. PMID 15044803 DOI: 10.1126/Science.1092645 |
0.358 |
|
| 2004 |
Fernández-Escamilla AM, Cheung MS, Vega MC, Wilmanns M, Onuchic JN, Serrano L. Solvation in protein folding analysis: combination of theoretical and experimental approaches. Proceedings of the National Academy of Sciences of the United States of America. 101: 2834-9. PMID 14978284 DOI: 10.1073/Pnas.0304180101 |
0.408 |
|
| 2004 |
Fernandez-Ballester G, Blanes-Mira C, Serrano L. The tryptophan switch: changing ligand-binding specificity from type I to type II in SH3 domains. Journal of Molecular Biology. 335: 619-29. PMID 14672668 DOI: 10.1016/J.Jmb.2003.10.060 |
0.372 |
|
| 2004 |
Villanueva J, Yanes O, Querol E, Serrano L, Aviles FX. Identification of protein ligands in complex biological samples using intensity-fading MALDI-TOF mass spectrometry. Analytical Chemistry. 75: 3385-95. PMID 14570188 DOI: 10.1021/Ac020644K |
0.365 |
|
| 2004 |
Lindorff-Larsen K, Paci E, Serrano L, Dobson CM, Vendruscolo M. Calculation of mutational free energy changes in transition states for protein folding. Biophysical Journal. 85: 1207-14. PMID 12885664 DOI: 10.1016/S0006-3495(03)74556-1 |
0.388 |
|
| 2004 |
Spagnolo L, Ventura S, Serrano L. Folding specificity induced by loop stiffness. Protein Science : a Publication of the Protein Society. 12: 1473-82. PMID 12824493 DOI: 10.1110/Ps.0302603 |
0.436 |
|
| 2003 |
Villanueva J, Villegas V, Querol E, Avilés FX, Serrano L. Monitoring disappearance of monomers and generation of resistance to proteolysis during the formation of the activation domain of human procarboxypeptidase A2 (ADA2h) amyloid fibrils by matrix-assisted laser-desorption ionization-time-of-flight-MS. The Biochemical Journal. 374: 489-95. PMID 12765547 DOI: 10.1042/Bj20030368 |
0.385 |
|
| 2003 |
Cobos ES, Filimonov VV, Vega MC, Mateo PL, Serrano L, Martínez JC. A thermodynamic and kinetic analysis of the folding pathway of an SH3 domain entropically stabilised by a redesigned hydrophobic core. Journal of Molecular Biology. 328: 221-33. PMID 12684010 DOI: 10.1016/S0022-2836(03)00273-0 |
0.414 |
|
| 2003 |
Jiménez MA, Villegas V, Santoro J, Serrano L, Vendrell J, Avilés FX, Rico M. NMR solution structure of the activation domain of human procarboxypeptidase A2. Protein Science : a Publication of the Protein Society. 12: 296-305. PMID 12538893 DOI: 10.1110/Ps.0227303 |
0.352 |
|
| 2003 |
Mendes J, Guerois R, Serrano L. Energy estimation in protein design. Current Opinion in Structural Biology. 12: 441-6. PMID 12163065 DOI: 10.1016/S0959-440X(02)00345-7 |
0.329 |
|
| 2003 |
Micheelsen MA, Rischel C, Ferkinghoff-Borg J, Guerois R, Serrano L. Mean first-passage time analysis reveals rate-limiting steps, parallel pathways and dead ends in a simple model of protein folding Europhysics Letters (Epl). 61: 561-566. DOI: 10.1209/Epl/I2003-00165-4 |
0.36 |
|
| 2003 |
Ventura S, Serrano L. Spectroscopic Analysis of Amyloid Fibril Formation in SH3-Domains Spectroscopy. 17: 647-652. DOI: 10.1155/2003/296902 |
0.357 |
|
| 2002 |
Schymkowitz JW, Rousseau F, Serrano L. Surfing on protein folding energy landscapes. Proceedings of the National Academy of Sciences of the United States of America. 99: 15846-8. PMID 12461186 DOI: 10.1073/Pnas.012686599 |
0.426 |
|
| 2002 |
López De La Paz M, Goldie K, Zurdo J, Lacroix E, Dobson CM, Hoenger A, Serrano L. De novo designed peptide-based amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America. 99: 16052-7. PMID 12456886 DOI: 10.1073/Pnas.252340199 |
0.356 |
|
| 2002 |
Ventura S, Lacroix E, Serrano L. Insights into the origin of the tendency of the PI3-SH3 domain to form amyloid fibrils. Journal of Molecular Biology. 322: 1147-58. PMID 12367534 DOI: 10.1016/S0022-2836(02)00783-0 |
0.374 |
|
| 2002 |
Villanueva J, Villegas V, Querol E, Avilés FX, Serrano L. Protein secondary structure and stability determined by combining exoproteolysis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Journal of Mass Spectrometry : Jms. 37: 974-84. PMID 12271440 DOI: 10.1002/Jms.356 |
0.429 |
|
| 2002 |
Reina J, Lacroix E, Hobson SD, Fernandez-Ballester G, Rybin V, Schwab MS, Serrano L, Gonzalez C. Computer-aided design of a PDZ domain to recognize new target sequences. Nature Structural Biology. 9: 621-7. PMID 12080331 DOI: 10.1038/Nsb815 |
0.397 |
|
| 2002 |
Guerois R, Nielsen JE, Serrano L. Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations. Journal of Molecular Biology. 320: 369-87. PMID 12079393 DOI: 10.1016/S0022-2836(02)00442-4 |
0.536 |
|
| 2002 |
Ventura S, Vega MC, Lacroix E, Angrand I, Spagnolo L, Serrano L. Conformational strain in the hydrophobic core and its implications for protein folding and design. Nature Structural Biology. 9: 485-93. PMID 12006985 DOI: 10.1038/Nsb799 |
0.378 |
|
| 2002 |
Viguera AR, Vega C, Serrano L. Unspecific hydrophobic stabilization of folding transition states. Proceedings of the National Academy of Sciences of the United States of America. 99: 5349-54. PMID 11959988 DOI: 10.1073/pnas.072387799 |
0.327 |
|
| 2002 |
Petukhov M, Uegaki K, Yumoto N, Serrano L. Amino acid intrinsic alpha-helical propensities III: positional dependence at several positions of C terminus. Protein Science : a Publication of the Protein Society. 11: 766-77. PMID 11910021 DOI: 10.1110/Ps.2610102 |
0.317 |
|
| 2002 |
Angrand I, Serrano L, Lacroix E. Computer-assisted re-design of spectrin SH3 residue clusters. Biomolecular Engineering. 18: 125-34. PMID 11566604 DOI: 10.1016/S1389-0344(01)00093-4 |
0.442 |
|
| 2001 |
Choma CT, Tieleman DP, Cregut D, Serrano L, Berendsen HJ. Towards the design and computational characterization of a membrane protein. Journal of Molecular Graphics & Modelling. 20: 219-34. PMID 11766047 DOI: 10.1016/S1093-3263(01)00111-5 |
0.365 |
|
| 2001 |
López de la Paz M, Lacroix E, Ramírez-Alvarado M, Serrano L. Computer-aided design of beta-sheet peptides. Journal of Molecular Biology. 312: 229-46. PMID 11545599 DOI: 10.1006/Jmbi.2001.4918 |
0.642 |
|
| 2001 |
Viguera AR, Serrano L. Bergerac-SH3: "frustation" induced by stabilizing the folding nucleus. Journal of Molecular Biology. 311: 357-71. PMID 11478866 DOI: 10.1006/Jmbi.2001.4738 |
0.453 |
|
| 2001 |
Ramírez-Alvarado M, Blanco FJ, Serrano L. Elongation of the BH8 beta-hairpin peptide: Electrostatic interactions in beta-hairpin formation and stability. Protein Science : a Publication of the Protein Society. 10: 1381-92. PMID 11420440 DOI: 10.1110/Ps.52901 |
0.639 |
|
| 2001 |
Garcia P, Serrano L, Durand D, Rico M, Bruix M. NMR and SAXS characterization of the denatured state of the chemotactic protein CheY: implications for protein folding initiation. Protein Science : a Publication of the Protein Society. 10: 1100-12. PMID 11369848 DOI: 10.1110/Ps.52701 |
0.456 |
|
| 2001 |
Nesmelova I, Krushelnitsky A, Idiyatullin D, Blanco F, Ramirez-Alvarado M, Daragan VA, Serrano L, Mayo KH. Conformational exchange on the microsecond time scale in alpha-helix and beta-hairpin peptides measured by 13C NMR transverse relaxation. Biochemistry. 40: 2844-53. PMID 11258895 DOI: 10.1021/Bi001293B |
0.581 |
|
| 2001 |
Guerois R, Serrano L. Protein design based on folding models. Current Opinion in Structural Biology. 11: 101-6. PMID 11179898 DOI: 10.1016/S0959-440X(00)00170-6 |
0.415 |
|
| 2001 |
Berisio R, Viguera A, Serrano L, Wilmanns M. Atomic resolution structure of a mutant of the spectrin SH3 domain. Acta Crystallographica. Section D, Biological Crystallography. 57: 337-40. PMID 11173498 DOI: 10.1107/S090744490001581X |
0.353 |
|
| 2001 |
Guerois R, Serrano L. The SH3-fold family: experimental evidence and prediction of variations in the folding pathways. Journal of Molecular Biology. 304: 967-82. PMID 11124040 DOI: 10.1006/Jmbi.2000.4234 |
0.442 |
|
| 2001 |
Villegas V, Zurdo J, Filimonov VV, Avilés FX, Dobson CM, Serrano L. Protein engineering as a strategy to avoid formation of amyloid fibrils. Protein Science : a Publication of the Protein Society. 9: 1700-8. PMID 11045616 DOI: 10.1110/Ps.9.9.1700 |
0.419 |
|
| 2000 |
Vega MC, Martínez JC, Serrano L. Thermodynamic and structural characterization of Asn and Ala residues in the disallowed II' region of the Ramachandran plot. Protein Science. 9: 2322-2328. PMID 11206053 DOI: 10.1110/Ps.9.12.2322 |
0.327 |
|
| 2000 |
Domingues H, Peters J, Schneider KH, Apeler H, Sebald W, Oschkinat H, Serrano L. Improving the refolding yield of interleukin-4 through the optimization of local interactions. Journal of Biotechnology. 84: 217-30. PMID 11164263 DOI: 10.1016/S0168-1656(00)00327-8 |
0.337 |
|
| 2000 |
Westerholm-Parvinen A, Vernos I, Serrano L. Kinesin subfamily UNC104 contains a FHA domain: boundaries and physicochemical characterization. Febs Letters. 486: 285-290. PMID 11119720 DOI: 10.1016/S0014-5793(00)02310-3 |
0.336 |
|
| 2000 |
Solà M, López-Hernández E, Cronet P, Lacroix E, Serrano L, Coll M, Párraga A. Towards understanding a molecular switch mechanism: thermodynamic and crystallographic studies of the signal transduction protein CheY. Journal of Molecular Biology. 303: 213-25. PMID 11023787 DOI: 10.1006/Jmbi.2000.4507 |
0.426 |
|
| 2000 |
Fernández AM, Villegas V, Martínez JC, Van Nuland NA, Conejero-Lara F, Avilés FX, Serrano L, Filimonov VV, Mateo PL. Thermodynamic analysis of helix-engineered forms of the activation domain of human procarboxypeptidase A2. European Journal of Biochemistry / Febs. 267: 5891-9. PMID 10998048 DOI: 10.1046/J.1432-1327.2000.01638.X |
0.352 |
|
| 2000 |
Taddei N, Chiti F, Fiaschi T, Bucciantini M, Capanni C, Stefani M, Serrano L, Dobson CM, Ramponi G. Stabilisation of alpha-helices by site-directed mutagenesis reveals the importance of secondary structure in the transition state for acylphosphatase folding. Journal of Molecular Biology. 300: 633-47. PMID 10884358 DOI: 10.1006/Jmbi.2000.3870 |
0.407 |
|
| 2000 |
Becskei A, Serrano L. Engineering stability in gene networks by autoregulation Nature. 405: 590-593. PMID 10850721 DOI: 10.1038/35014651 |
0.302 |
|
| 2000 |
Kortemme T, Kelly MJ, Kay LE, Forman-Kay J, Serrano L. Similarities between the spectrin SH3 domain denatured state and its folding transition state. Journal of Molecular Biology. 297: 1217-29. PMID 10764585 DOI: 10.1006/Jmbi.2000.3618 |
0.654 |
|
| 2000 |
Serrano L. The relationship between sequence and structure in elementary folding units. Advances in Protein Chemistry. 53: 49-85. PMID 10751943 DOI: 10.1016/S0065-3233(00)53002-2 |
0.396 |
|
| 2000 |
Wallon G, Rappsilber J, Mann M, Serrano L. Model for stathmin/OP18 binding to tubulin Embo Journal. 19: 213-222. PMID 10637225 DOI: 10.1093/Emboj/19.2.213 |
0.311 |
|
| 2000 |
Petukhov M, Uegaki K, Yumoto N, Yoshikawa S, Serrano L. Position dependence of amino acid intrinsic helical propensities II: non-charged polar residues: Ser, Thr, Asn, and Gln. Protein Science : a Publication of the Protein Society. 8: 2144-50. PMID 10548060 DOI: 10.1110/Ps.8.10.2144 |
0.331 |
|
| 2000 |
Petukhov M, Cregut D, Soares CM, Serrano L. Local water bridges and protein conformational stability. Protein Science : a Publication of the Protein Society. 8: 1982-9. PMID 10548043 DOI: 10.1110/Ps.8.10.1982 |
0.357 |
|
| 2000 |
Viguera AR, Serrano L. Stable proline box motif at the N-terminal end of alpha-helices. Protein Science : a Publication of the Protein Society. 8: 1733-42. PMID 10493574 DOI: 10.1110/Ps.8.9.1733 |
0.361 |
|
| 1999 |
Martinez JC, Serrano L. The folding transition state between SH3 domains is conformationally restricted and evolutionary conserved Nature Structural Biology. 6: 1010-1016. PMID 10542091 DOI: 10.1038/14896 |
0.423 |
|
| 1999 |
Cregut D, Civera C, Macias MJ, Wallon G, Serrano L. A tale of two secondary structure elements: when a beta-hairpin becomes an alpha-helix. Journal of Molecular Biology. 292: 389-401. PMID 10493883 DOI: 10.1006/Jmbi.1999.2966 |
0.493 |
|
| 1999 |
Lacroix E, Kortemme T, Lopez de la Paz M, Serrano L. The design of linear peptides that fold as monomeric beta-sheet structures. Current Opinion in Structural Biology. 9: 487-93. PMID 10449370 DOI: 10.1016/S0959-440X(99)80069-4 |
0.675 |
|
| 1999 |
Filimonov VV, Azuaga AI, Viguera AR, Serrano L, Mateo PL. A thermodynamic analysis of a family of small globular proteins: SH3 domains. Biophysical Chemistry. 77: 195-208. PMID 10326252 DOI: 10.1016/S0301-4622(99)00025-3 |
0.371 |
|
| 1999 |
Ramírez-Alvarado M, Kortemme T, Blanco FJ, Serrano L. Beta-hairpin and beta-sheet formation in designed linear peptides. Bioorganic & Medicinal Chemistry. 7: 93-103. PMID 10199660 DOI: 10.1016/S0968-0896(98)00215-6 |
0.745 |
|
| 1999 |
Cregut D, Serrano L. Molecular dynamics as a tool to detect protein foldability. A mutant of domain B1 of protein G with non-native secondary structure propensities. Protein Science : a Publication of the Protein Society. 8: 271-82. PMID 10048320 DOI: 10.1110/Ps.8.2.271 |
0.409 |
|
| 1999 |
Blanco FJ, Angrand I, Serrano L. Exploring the conformational properties of the sequence space between two proteins with different folds: an experimental study. Journal of Molecular Biology. 285: 741-53. PMID 9878441 DOI: 10.1006/Jmbi.1998.2333 |
0.454 |
|
| 1999 |
Solá M, Gomis-Rüth FX, Serrano L, González A, Coll M. Three-dimensional crystal structure of the transcription factor PhoB receiver domain. Journal of Molecular Biology. 285: 675-87. PMID 9878437 DOI: 10.1006/Jmbi.1998.2326 |
0.365 |
|
| 1999 |
Lacroix E, Viguera AR, Serrano L. Elucidating the folding problem of alpha-helices: local motifs, long-range electrostatics, ionic-strength dependence and prediction of NMR parameters. Journal of Molecular Biology. 284: 173-91. PMID 9811549 DOI: 10.1006/Jmbi.1998.2145 |
0.418 |
|
| 1998 |
Blanco FJ, Serrano L, Forman-Kay JD. High populations of non-native structures in the denatured state are compatible with the formation of the native folded state Journal of Molecular Biology. 284: 1153-1164. PMID 9837733 DOI: 10.1006/Jmbi.1998.2229 |
0.413 |
|
| 1998 |
Vázquez MI, Rivas G, Cregut D, Serrano L, Esteban M. The vaccinia virus 14-kilodalton (A27L) fusion protein forms a triple coiled-coil structure and interacts with the 21-kilodalton (A17L) virus membrane protein through a C-terminal α-helix Journal of Virology. 72: 10126-10137. PMID 9811753 DOI: 10.1128/Jvi.72.12.10126-10137.1998 |
0.416 |
|
| 1998 |
Villegas V, Martínez JC, Avilés FX, Serrano L. Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain. Journal of Molecular Biology. 283: 1027-36. PMID 9799641 DOI: 10.1006/Jmbi.1998.2158 |
0.418 |
|
| 1998 |
Wilcock D, Pisabarro MT, López-Hernandez E, Serrano L, Coll M. Structure analysis of two CheY mutants: importance of the hydrogen-bond contribution to protein stability. Acta Crystallographica. Section D, Biological Crystallography. 54: 378-85. PMID 9761905 DOI: 10.1107/S0907444997012158 |
0.343 |
|
| 1998 |
Martinez JC, Pisabarro MT, Serrano L. Obligatory steps in protein folding and the conformational diversity of the transition state. Nature Structural & Molecular Biology. 5: 721-729. PMID 9699637 DOI: 10.1038/1418 |
0.38 |
|
| 1998 |
Pisabarro MT, Serrano L, Wilmanns M. Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions. Journal of Molecular Biology. 281: 513-21. PMID 9698566 DOI: 10.1006/Jmbi.1998.1932 |
0.386 |
|
| 1998 |
Kortemme T, Ramírez-Alvarado M, Serrano L. Design of a 20-amino acid, three-stranded beta-sheet protein. Science (New York, N.Y.). 281: 253-6. PMID 9657719 DOI: 10.1126/Science.281.5374.253 |
0.742 |
|
| 1998 |
Petukhov M, Muñoz V, Yumoto N, Yoshikawa S, Serrano L. Position dependence of non-polar amino acid intrinsic helical propensities. Journal of Molecular Biology. 278: 279-89. PMID 9571050 DOI: 10.1006/Jmbi.1998.1682 |
0.614 |
|
| 1998 |
Lacroix E, Viguera AR, Serrano L. Reading protein sequences backwards. Folding & Design. 3: 79-85. PMID 9565752 DOI: 10.1016/S1359-0278(98)00013-3 |
0.382 |
|
| 1998 |
Ramirez-Alvarado M, Daragan VA, Serrano L, Mayo KH. Motional dynamics of residues in a beta-hairpin peptide measured by 13C-NMR relaxation. Protein Science : a Publication of the Protein Society. 7: 720-9. PMID 9541404 DOI: 10.1002/Pro.5560070321 |
0.571 |
|
| 1998 |
Blanco F, Ramírez-Alvarado M, Serrano L. Formation and stability of beta-hairpin structures in polypeptides. Current Opinion in Structural Biology. 8: 107-11. PMID 9519303 DOI: 10.1016/S0959-440X(98)80017-1 |
0.647 |
|
| 1998 |
Prieto J, Serrano L. C-capping and helix stability: the Pro C-capping motif. Journal of Molecular Biology. 274: 276-88. PMID 9398533 DOI: 10.1006/Jmbi.1997.1322 |
0.361 |
|
| 1998 |
Martinez J, Viguera A, Serrano L, Filimonov V, Mateo P. The DSC data analysis for small, single-domain proteins. Application to the SH3 domain Reactive and Functional Polymers. 36: 221-225. DOI: 10.1016/S1381-5148(97)00088-6 |
0.368 |
|
| 1997 |
Ramírez-Alvarado M, Blanco FJ, Niemann H, Serrano L. Role of beta-turn residues in beta-hairpin formation and stability in designed peptides. Journal of Molecular Biology. 273: 898-912. PMID 9367780 DOI: 10.1006/Jmbi.1997.1347 |
0.659 |
|
| 1997 |
Viguera AR, Serrano L. Loop length, intramolecular diffusion and protein folding. Nature Structural Biology. 4: 939-46. PMID 9360611 DOI: 10.1038/Nsb1197-939 |
0.377 |
|
| 1997 |
Lacroix E, Bruix M, López-Hernández E, Serrano L, Rico M. Amide hydrogen exchange and internal dynamics in the chemotactic protein CheY from Escherichia coli. Journal of Molecular Biology. 271: 472-87. PMID 9268672 DOI: 10.1006/Jmbi.1997.1178 |
0.417 |
|
| 1997 |
Blanco FJ, Ortiz AR, Serrano L. 1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure. Journal of Biomolecular Nmr. 9: 347-57. PMID 9255941 DOI: 10.1023/A:1018330122908 |
0.312 |
|
| 1997 |
Prieto J, Wilmans M, Jiménez MA, Rico M, Serrano L. Non-native local interactions in protein folding and stability: introducing a helical tendency in the all beta-sheet alpha-spectrin SH3 domain. Journal of Molecular Biology. 268: 760-78. PMID 9175859 DOI: 10.1006/Jmbi.1997.0984 |
0.474 |
|
| 1997 |
Blanco FJ, Ortiz AR, Serrano L. Role of a nonnative interaction in the folding of the protein G B1 domain as inferred from the conformational analysis of the alpha-helix fragment. Folding & Design. 2: 123-33. PMID 9135985 DOI: 10.1016/S1359-0278(97)00017-5 |
0.474 |
|
| 1997 |
Muñoz V, Serrano L. Development of the multiple sequence approximation within the AGADIR model of alpha-helix formation: comparison with Zimm-Bragg and Lifson-Roig formalisms. Biopolymers. 41: 495-509. PMID 9095674 DOI: 10.1002/(Sici)1097-0282(19970415)41:5<495::Aid-Bip2>3.0.Co;2-H |
0.614 |
|
| 1997 |
Viguera AR, Villegas V, Avilés FX, Serrano L. Favourable native-like helical local interactions can accelerate protein folding. Folding & Design. 2: 23-33. PMID 9080196 DOI: 10.1016/S1359-0278(97)00003-5 |
0.46 |
|
| 1997 |
Muñoz V, Serrano L. Local versus nonlocal interactions in protein folding and stability--an experimentalist's point of view. Folding & Design. 1: R71-7. PMID 9079385 DOI: 10.1016/S1359-0278(96)00036-3 |
0.588 |
|
| 1997 |
Muñoz V, Cronet P, López-Hernández E, Serrano L. Analysis of the effect of local interactions on protein stability. Folding & Design. 1: 167-78. PMID 9079379 DOI: 10.1016/S1359-0278(96)00029-6 |
0.632 |
|
| 1997 |
López-Hernández E, Cronet P, Serrano L, Muñoz V. Folding kinetics of Che Y mutants with enhanced native alpha-helix propensities. Journal of Molecular Biology. 266: 610-20. PMID 9067614 DOI: 10.1006/Jmbi.1996.0793 |
0.657 |
|
| 1997 |
Bruix M, Muñoz V, Campos-Olivas R, Del Bosque JR, Serrano L, Rico M. Characterisation of the isolated Che Y C-terminal fragment (79-129)--Exploring the structure/stability/folding relationship of the alpha/beta parallel protein Che Y. European Journal of Biochemistry. 243: 384-92. PMID 9030763 DOI: 10.1111/J.1432-1033.1997.0384A.X |
0.623 |
|
| 1997 |
Ramírez-Alvarado M, Serrano L, Blanco FJ. Conformational analysis of peptides corresponding to all the secondary structure elements of protein L B1 domain: secondary structure propensities are not conserved in proteins with the same fold. Protein Science : a Publication of the Protein Society. 6: 162-74. PMID 9007989 DOI: 10.1002/pro.5560060119 |
0.657 |
|
| 1996 |
Viguera AR, Serrano L, Wilmanns M. Different folding transition states may result in the same native structure. Nature Structural Biology. 3: 874-80. PMID 8836105 DOI: 10.1038/Nsb1096-874 |
0.381 |
|
| 1996 |
Ramírez-Alvarado M, Blanco FJ, Serrano L. De novo design and structural analysis of a model beta-hairpin peptide system. Nature Structural Biology. 3: 604-12. PMID 8673604 DOI: 10.1038/Nsb0796-604 |
0.64 |
|
| 1996 |
Bellsolell L, Cronet P, Majolero M, Serrano L, Coll M. The three-dimensional structure of two mutants of the signal transduction protein CheY suggest its molecular activation mechanism. Journal of Molecular Biology. 257: 116-28. PMID 8632450 DOI: 10.1006/Jmbi.1996.0151 |
0.388 |
|
| 1996 |
Viguera AR, Jiménez MA, Rico M, Serrano L. Conformational analysis of peptides corresponding to β-hairpins and a β-sheet that represent the entire sequence of the α-spectrin SH3 domain Journal of Molecular Biology. 255: 507-521. PMID 8568894 DOI: 10.1006/Jmbi.1996.0042 |
0.335 |
|
| 1996 |
Muñoz V, Blanco FJ, Serrano L. The distribution of alpha-helix propensity along the polypeptide chain is not conserved in proteins from the same family. Protein Science : a Publication of the Protein Society. 4: 1577-86. PMID 8520484 DOI: 10.1002/Pro.5560040816 |
0.604 |
|
| 1996 |
López-Hernéndez E, Serrano L. Structure of the transition state for folding of the 129 aa protein CheY resembles that of a smaller protein, CI-2 Folding and Design. 1: 43-55. DOI: 10.1016/S1359-0278(96)00011-9 |
0.414 |
|
| 1996 |
Villegas V, Viguera AR, Avilés FX, Serrano L. Stabilization of proteins by rational design of α-helix stability using helix/coil transition theory Folding and Design. 1: 29-34. DOI: 10.1016/S1359-0278(96)00009-0 |
0.435 |
|
| 1995 |
Pisabarro MT, Ortiz AR, Serrano L, Wade RC. Homology modeling of the Abl-SH3 domain. Proteins. 20: 203-15. PMID 7892170 DOI: 10.1002/Prot.340200302 |
0.41 |
|
| 1995 |
Muñoz V, Serrano L. Elucidating the Folding Problem of Helical Peptides using Empirical Parameters. III>Temperature and pH Dependence Journal of Molecular Biology. 245: 297-308. PMID 7844818 DOI: 10.1006/Jmbi.1994.0024 |
0.627 |
|
| 1995 |
Muñoz V, Serrano L. Elucidating the folding problem of helical peptides using empirical parameters. II. Helix macrodipole effects and rational modification of the helical content of natural peptides. Journal of Molecular Biology. 245: 275-296. PMID 7844817 DOI: 10.1006/Jmbi.1994.0023 |
0.657 |
|
| 1995 |
Cronet P, Bellsolell L, Sander C, Coll M, Serrano L. Investigating the structural determinants of the p21-like triphosphate and Mg2+ binding site. Journal of Molecular Biology. 249: 654-64. PMID 7783218 DOI: 10.1006/Jmbi.1995.0326 |
0.372 |
|
| 1995 |
Muñoz V, Serrano L. Intrinsic secondary structure propensities of the amino acids, using statistical phi-psi matrices: comparison with experimental scales. Proteins. 20: 301-11. PMID 7731949 DOI: 10.1002/Prot.340200403 |
0.601 |
|
| 1995 |
Muñoz V, Serrano L, Jiménez MA, Rico M. Structural analysis of peptides encompassing all α-helices of three α/β parallel proteins: Che-Y, flavodoxin and P21-Ras: Implications for α-Helix stability and the folding of α/β parallel proteins Journal of Molecular Biology. 247: 648-669. PMID 7723021 DOI: 10.1016/S0022-2836(05)80145-7 |
0.633 |
|
| 1995 |
Pisabarro MT, Ortiz AR, Viguera AR, Gago F, Serrano L. Molecular modeling of the interaction of polyproline-based peptides with the Abl-SH3 domain: rational modification of the interaction. Protein Engineering. 7: 1455-62. PMID 7716156 DOI: 10.1093/Protein/7.12.1455 |
0.366 |
|
| 1995 |
Muñoz V, Blanco FJ, Serrano L. The hydrophobic-staple motif and a role for loop-residues in alpha-helix stability and protein folding. Nature Structural Biology. 2: 380-5. PMID 7664095 DOI: 10.1038/Nsb0595-380 |
0.663 |
|
| 1995 |
Muñoz V, Serrano L. Elucidating the folding problem of helical peptides using empirical parameters. Nature Structural Biology. 1: 399-409. PMID 7664054 DOI: 10.1038/Nsb0694-399 |
0.607 |
|
| 1995 |
Viguera AR, Serrano L. Experimental analysis of the Schellman motif. Journal of Molecular Biology. 251: 150-60. PMID 7643384 DOI: 10.1006/Jmbi.1995.0422 |
0.428 |
|
| 1995 |
Viguera AR, Serrano L. Side-chain interactions between sulfur-containing amino acids and phenylalanine in alpha-helices. Biochemistry. 34: 8771-9. PMID 7612617 DOI: 10.1021/Bi00027A028 |
0.407 |
|
| 1995 |
Muñoz V, Serrano L. Helix design, prediction and stability. Current Opinion in Biotechnology. 6: 382-6. PMID 7579647 DOI: 10.1016/0958-1669(95)80066-2 |
0.625 |
|
| 1995 |
Muñoz V, Serrano L. Analysis of i,i+5 and i,i+8 hydrophobic interactions in a helical model peptide bearing the hydrophobic staple motif. Biochemistry. 34: 15301-6. PMID 7578146 DOI: 10.1021/Bi00046A039 |
0.588 |
|
| 1995 |
Villegas V, Azuaga A, Catasús L, Reverter D, Mateo PL, Avilés FX, Serrano L. Evidence for a two-state transition in the folding process of the activation domain of human procarboxypeptidase A2. Biochemistry. 34: 15105-10. PMID 7578124 DOI: 10.1021/Bi00046A017 |
0.405 |
|
| 1995 |
Serrano L. Comparison between the φ Distribution of the Amino Acids in the Protein Database and NMR Data Indicates that Amino Acids have Various φ Propensities in the Random Coil Conformation Journal of Molecular Biology. 254: 322-333. PMID 7490751 DOI: 10.1006/Jmbi.1995.0619 |
0.384 |
|
| 1995 |
López-Hernández E, Serrano L. Empirical correlation for the replacement of Ala by Gly: importance of amino acid secondary intrinsic propensities. Proteins. 22: 340-9. PMID 7479708 DOI: 10.1002/Prot.340220405 |
0.361 |
|
| 1995 |
Blanco FJ, Serrano L. Folding Of Protein G B1 Domain Studied By The Conformational Characterization Of Fragments Comprising Its Secondary Structure Elements Febs Journal. 230: 634-649. DOI: 10.1111/J.1432-1033.1995.0634H.X |
0.422 |
|
| 1995 |
Santoro J, Bruix M, Pascual J, López E, Serrano L, Rico M. Three-dimensional structure of chemotactic che Y protein in aqueous solution by nuclear magnetic resonance methods Journal of Molecular Biology. 247: 717-725. DOI: 10.1016/S0022-2836(05)80150-0 |
0.342 |
|
| 1995 |
Viguera AR, Blanco FJ, Serrano L. The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics Journal of Molecular Biology. 247: 670-681. DOI: 10.1016/S0022-2836(05)80146-9 |
0.428 |
|
| 1994 |
Muñoz V, Lopez EM, Jager M, Serrano L. Kinetic characterization of the chemotactic protein from Escherichia coli, CheY. Kinetic analysis of the inverse hydrophobic effect. Biochemistry. 33: 5858-66. PMID 8180214 DOI: 10.1021/Bi00185A025 |
0.604 |
|
| 1994 |
Bellsolell L, Prieto J, Serrano L, Coll M. Magnesium Binding to the Bacterial Chemotaxis Protein CheY Results in Large Conformational Changes Involving its Functional Surface Journal of Molecular Biology. 238: 489-495. PMID 8176739 DOI: 10.1006/Jmbi.1994.1308 |
0.392 |
|
| 1994 |
Viguera AR, Arrondo JL, Musacchio A, Saraste M, Serrano L. Characterization of the interaction of natural proline-rich peptides with five different SH3 domains. Biochemistry. 33: 10925-33. PMID 8086409 DOI: 10.1021/Bi00202A011 |
0.375 |
|
| 1994 |
Jiménez MA, Muñoz V, Rico M, Serrano L. Helix stop and start signals in peptides and proteins: The capping box does not necessarily prevent helix elongation Journal of Molecular Biology. 242: 487-496. PMID 7932705 DOI: 10.1006/JMBI.1994.1596 |
0.588 |
|
| 1994 |
Blanco FJ, Rivas G, Serrano L. A short linear peptide that folds into a native stable β-hairpin in aqueous solution Nature Structural Biology. 1: 584-590. PMID 7634098 DOI: 10.1038/Nsb0994-584 |
0.4 |
|
| 1994 |
Serrano L. Protein engineering and the dissection of protein folding pathways Current Opinion in Structural Biology. 4: 107-111. DOI: 10.1016/S0959-440X(94)90067-1 |
0.367 |
|
| 1993 |
Serrano L, Day AG, Fersht AR. Step-wise mutation of barnase to binase. A procedure for engineering increased stability of proteins and an experimental analysis of the evolution of protein stability. Journal of Molecular Biology. 233: 305-12. PMID 8377205 DOI: 10.1006/Jmbi.1993.1508 |
0.374 |
|
| 1993 |
Bruix M, Pascual J, Santoro J, Prieto J, Serrano L, Rico M. 1H- and 15N-NMR assignment and solution structure of the chemotactic Escherichia coli Che Y protein. European Journal of Biochemistry. 215: 573-85. PMID 8354264 DOI: 10.1111/J.1432-1033.1993.Tb18068.X |
0.391 |
|
| 1993 |
Padilla R, Otin CL, Serrano L, Avila J. Role of the carboxy terminal region of β tubulin on microtubule dynamics through its interaction with the GTP phosphate binding region Febs Letters. 325: 173-176. PMID 8319803 DOI: 10.1016/0014-5793(93)81067-A |
0.308 |
|
| 1993 |
Filimonov VV, Prieto J, Martinez JC, Bruix M, Mateo PL, Serrano L. Thermodynamic analysis of the chemotactic protein from Escherichia coli, CheY. Biochemistry. 32: 12906-12921. PMID 8251514 DOI: 10.1021/Bi00210A045 |
0.425 |
|
| 1993 |
Fersht AR, Matouschek A, Sancho J, Serrano L, Vuilleumier S. Pathway of protein folding. Faraday Discussions. 183-93. PMID 1290932 DOI: 10.1039/Fd9929300183 |
0.46 |
|
| 1993 |
Fersht AR, Jackson SE, Serrano L. Protein stability : experimental data from protein engineering Philosophical Transactions of the Royal Society A. 345: 141-151. DOI: 10.1098/Rsta.1993.0125 |
0.429 |
|
| 1993 |
Fersht AR, Serrano L. Principles of protein stability derived from protein engineering experiments Current Opinion in Structural Biology. 3: 75-83. DOI: 10.1016/0959-440X(93)90205-Y |
0.399 |
|
| 1992 |
Meiering EM, Serrano L, Fersht AR. Effect of active site residues in barnase on activity and stability. Journal of Molecular Biology. 225: 585-9. PMID 1602471 DOI: 10.1016/0022-2836(92)90387-Y |
0.329 |
|
| 1992 |
Serrano L, Matouschek A, Fersht AR. The folding of an enzyme. VI. The folding pathway of barnase: comparison with theoretical models. Journal of Molecular Biology. 224: 847-59. PMID 1569561 DOI: 10.1016/0022-2836(92)90566-3 |
0.444 |
|
| 1992 |
Matouschek A, Serrano L, Meiering EM, Bycroft M, Fersht AR. The folding of an enzyme. V. H/2H exchange-nuclear magnetic resonance studies on the folding pathway of barnase: complementarity to and agreement with protein engineering studies. Journal of Molecular Biology. 224: 837-45. PMID 1569560 DOI: 10.1016/0022-2836(92)90565-2 |
0.431 |
|
| 1992 |
Matouschek A, Serrano L, Fersht AR. The folding of an enzyme. IV. Structure of an intermediate in the refolding of barnase analysed by a protein engineering procedure. Journal of Molecular Biology. 224: 819-35. PMID 1569559 DOI: 10.1016/0022-2836(92)90564-Z |
0.353 |
|
| 1992 |
Serrano L, Matouschek A, Fersht AR. The folding of an enzyme. III. Structure of the transition state for unfolding of barnase analysed by a protein engineering procedure. Journal of Molecular Biology. 224: 805-18. PMID 1569558 DOI: 10.1016/0022-2836(92)90563-Y |
0.441 |
|
| 1992 |
Serrano L, Kellis JT, Cann P, Matouschek A, Fersht AR. The folding of an enzyme. II. Substructure of barnase and the contribution of different interactions to protein stability. Journal of Molecular Biology. 224: 783-804. PMID 1569557 DOI: 10.1016/0022-2836(92)90562-X |
0.39 |
|
| 1992 |
Fersht AR, Matouschek A, Serrano L. The folding of an enzyme. I. Theory of protein engineering analysis of stability and pathway of protein folding. Journal of Molecular Biology. 224: 771-82. PMID 1569556 DOI: 10.1016/0022-2836(92)90561-W |
0.407 |
|
| 1992 |
Serrano L, Neira JL, Sancho J, Fersht AR. Effect of alanine versus glycine in alpha-helices on protein stability. Nature. 356: 453-5. PMID 1557131 DOI: 10.1038/356453A0 |
0.432 |
|
| 1992 |
Sancho J, Serrano L, Fersht AR. Histidine residues at the N- and C-termini of alpha-helices: perturbed pKas and protein stability. Biochemistry. 31: 2253-8. PMID 1540580 DOI: 10.1021/Bi00123A006 |
0.381 |
|
| 1992 |
Serrano L, Sancho J, Hirshberg M, Fersht AR. Alpha-helix stability in proteins. I. Empirical correlations concerning substitution of side-chains at the N and C-caps and the replacement of alanine by glycine or serine at solvent-exposed surfaces. Journal of Molecular Biology. 227: 544-59. PMID 1404368 DOI: 10.1016/0022-2836(92)90906-Z |
0.36 |
|
| 1991 |
Horovitz A, Serrano L, Fersht AR. COSMIC analysis of the major α-helix of barnase during folding Journal of Molecular Biology. 219: 5-9. PMID 2023260 DOI: 10.1016/0022-2836(91)90852-W |
0.429 |
|
| 1991 |
Serrano L, Bycroft M, Fersht AR. Aromatic-aromatic interactions and protein stability. Investigation by double-mutant cycles. Journal of Molecular Biology. 218: 465-75. PMID 2010920 DOI: 10.1016/0022-2836(91)90725-L |
0.436 |
|
| 1991 |
Fersht AR, Bycroft M, Horovitz A, Kellis JT, Matouschek A, Serrano L. Pathway and stability of protein folding Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 332: 171-176. PMID 1678536 DOI: 10.1098/Rstb.1991.0046 |
0.459 |
|
| 1991 |
Fersht AR, Matouschek AT, Bycroft M, Kellis JT, Serrano L. Physical-Organic Molecular Biology : Pathway And Stability Of Protein Folding Pure and Applied Chemistry. 63: 187-194. DOI: 10.1351/Pac199163020187 |
0.447 |
|
| 1990 |
Bycroft M, Matouschek AT, Kellis JT, Serrano L, Fersht AR. Detection and characterization of a folding intermediate in barnase by NMR Nature. 346: 488-490. PMID 2377210 DOI: 10.1038/346488A0 |
0.424 |
|
| 1990 |
Matouschek AT, Kellis JT, Serrano L, Bycroft M, Fersht AR. Transient folding intermediates characterized by protein engineering Nature. 346: 440-445. PMID 2377205 DOI: 10.1038/346440A0 |
0.394 |
|
| 1990 |
Horovitz A, Serrano L, Avron B, Bycroft M, Fersht AR. Strength and co-operativity of contributions of surface salt bridges to protein stability Journal of Molecular Biology. 216: 1031-1044. PMID 2266554 DOI: 10.1016/S0022-2836(99)80018-7 |
0.423 |
|
| 1990 |
Serrano L, Horovitz A, Avron B, Bycroft M, Fersht AR. Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles Biochemistry®. 29: 9343-9352. PMID 2248951 DOI: 10.1021/Bi00492A006 |
0.348 |
|
| 1989 |
Serrano L, Fersht AR. Capping and alpha-helix stability. Nature. 342: 296-9. PMID 2812029 DOI: 10.1038/342296A0 |
0.335 |
|
| 1989 |
Matouschek AT, Kellis JT, Serrano L, Fersht AR. Mapping the transition state and pathway of protein folding by protein engineering Nature. 340: 122-126. PMID 2739734 DOI: 10.1038/340122A0 |
0.368 |
|
| 1988 |
Valencia A, Serrano L, Caballero R, Anderson PS, Lacal JC. Conformational alterations detected by circular dichroism induced in the normal ras p21 protein by activating point mutations at position 12, 59, or 61. European Journal of Biochemistry / Febs. 174: 621-7. PMID 3292238 DOI: 10.1111/J.1432-1033.1988.Tb14143.X |
0.375 |
|
| 1987 |
Avila J, Serrano L, Maccioni RB. Regulatory aspects of the colchicine interactions with tubulin. Molecular and Cellular Biochemistry. 73: 29-36. PMID 3543651 DOI: 10.1007/Bf00229373 |
0.339 |
|
| 1984 |
Serrano L, Avila J, Maccioni RB. Controlled proteolysis of tubulin by subtilisin: localization of the site for MAP2 interaction. Biochemistry. 23: 4675-81. PMID 6388633 DOI: 10.1021/Bi00315A024 |
0.338 |
|
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