Ana Lucia Severo Rodrigues - Publications

Affiliations: 
Biochemistry Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil 
Area:
antidepressants

189 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Galts CPC, Bettio LEB, Jewett DC, Yang CC, Brocardo PS, Rodrigues ALS, Thacker JS, Gil-Mohapel J. Depression in Neurodegenerative Diseases: Common Mechanisms and Current Treatment Options. Neuroscience and Biobehavioral Reviews. PMID 30995512 DOI: 10.1016/j.neubiorev.2019.04.002  0.72
2019 Casseb GAS, Ambrósio G, Rodrigues ALS, Kaster MP. Levels of 25-hydroxyvitamin D, biochemical parameters and symptoms of depression and anxiety in healthy individuals. Metabolic Brain Disease. PMID 30604028 DOI: 10.1007/s11011-018-0371-7  0.84
2018 Pazini FL, Cunha MP, Rodrigues ALS. The possible beneficial effects of creatine for the management of depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 89: 193-206. PMID 30193988 DOI: 10.1016/j.pnpbp.2018.08.029  0.84
2018 de Paula Nascimento-Castro C, Wink AC, da Fônseca VS, Bianco CD, Winkelmann-Duarte EC, Farina M, Rodrigues ALS, Gil-Mohapel J, de Bem AF, Brocardo PS. Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington's Disease. Neural Plasticity. 2018: 4056383. PMID 30186318 DOI: 10.1155/2018/4056383  0.72
2018 Neis VB, Bettio LB, Moretti M, Rosa PB, Olescowicz G, Fraga DB, Gonçalves FM, Freitas AE, Heinrich IA, Lopes MW, Leal RB, Rodrigues ALS. Single administration of agmatine reverses the depressive-like behavior induced by corticosterone in mice: Comparison with ketamine and fluoxetine. Pharmacology, Biochemistry, and Behavior. 173: 44-50. PMID 30125592 DOI: 10.1016/j.pbb.2018.08.005  0.56
2018 Neis VB, Rosa PB, Moretti M, Rodrigues ALS. Involvement of Heme Oxygenase-1 in Neuropsychiatric and Neurodegenerative Diseases. Current Pharmaceutical Design. PMID 30019638 DOI: 10.2174/1381612824666180717160623  0.48
2018 Cunha MP, Pazini FL, Lieberknecht V, Rodrigues ALS. Subchronic administration of creatine produces antidepressant-like effect by modulating hippocampal signaling pathway mediated by FNDC5/BDNF/Akt in mice. Journal of Psychiatric Research. 104: 78-87. PMID 30005372 DOI: 10.1016/j.jpsychires.2018.07.001  0.84
2018 Tavares MK, Dos Reis S, Platt N, Heinrich IA, Wolin IAV, Leal RB, Kaster MP, Rodrigues ALS, Freitas AE. Agmatine potentiates neuroprotective effects of subthreshold concentrations of ketamine via mTOR/S6 kinase signaling pathway. Neurochemistry International. PMID 29763645 DOI: 10.1016/j.neuint.2018.05.006  0.84
2018 Rosa JM, Pazini FL, Cunha MP, Colla ARS, Manosso LM, Mancini G, Souza ACG, de Bem AF, Prediger RD, Rodrigues ALS. Antidepressant effects of creatine on amyloid β-treated mice: The role of GSK-3β/Nrf pathway. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29753049 DOI: 10.1016/j.pnpbp.2018.05.001  0.84
2018 do Espírito Santo CC, Secco DD, Meireles A, de Freitas GR, Bobinski F, Cunha MP, Rodrigues ALS, Swarowsky A, Santos ARS, Ilha J. Locomotor Treadmill Training Promotes Soleus Trophism by Mammalian Target of Rapamycin Pathway in Paraplegic Rats. Neurochemical Research. PMID 29737479 DOI: 10.1007/s11064-018-2543-6  0.76
2018 Ambrósio G, Kaufmann FN, Manosso L, Platt N, Ghisleni G, Rodrigues ALS, Rieger DK, Kaster MP. Depression and peripheral inflammatory profile of patients with obesity. Psychoneuroendocrinology. 91: 132-141. PMID 29550676 DOI: 10.1016/j.psyneuen.2018.03.005  0.84
2018 Siteneski A, Cunha MP, Lieberknecht V, Pazini FL, Gruhn K, Brocardo PS, Rodrigues ALS. Central irisin administration affords antidepressant-like effect and modulates neuroplasticity-related genes in the hippocampus and prefrontal cortex of mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29524513 DOI: 10.1016/j.pnpbp.2018.03.004  0.84
2018 Fraga DB, Olescowicz G, Moretti M, Siteneski A, Tavares MK, Azevedo D, Colla ARS, Rodrigues ALS. Anxiolytic effects of ascorbic acid and ketamine in mice. Journal of Psychiatric Research. 100: 16-23. PMID 29475017 DOI: 10.1016/j.jpsychires.2018.02.006  0.52
2018 da Fonsêca VS, da Silva Colla AR, de Paula Nascimento-Castro C, Plácido E, Rosa JM, Farina M, Gil-Mohapel J, Rodrigues ALS, Brocardo PS. Brain-Derived Neurotrophic Factor Prevents Depressive-Like Behaviors in Early-Symptomatic YAC128 Huntington's Disease Mice. Molecular Neurobiology. PMID 29388082 DOI: 10.1007/s12035-018-0890-6  0.76
2017 Moretti M, Ribeiro CM, Neis VB, Bettio LEB, Rosa PB, Rodrigues ALS. Evidence for the involvement of opioid system in the antidepressant-like effect of ascorbic acid. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 29222646 DOI: 10.1007/s00210-017-1446-4  0.48
2017 Engel DF, de Oliveira J, Lieberknecht V, Rodrigues ALS, de Bem AF, Gabilan NH. Duloxetine Protects Human Neuroblastoma Cells from Oxidative Stress-Induced Cell Death Through Akt/Nrf-2/HO-1 Pathway. Neurochemical Research. PMID 29134401 DOI: 10.1007/s11064-017-2433-3  0.6
2017 Ramos-Hryb AB, Cunha MP, Pazini FL, Lieberknecht V, Prediger RDS, Kaster MP, Rodrigues ALS. Ursolic acid affords antidepressant-like effects in mice through the activation of PKA, PKC, CAMK-II and MEK1/2. Pharmacological Reports : Pr. 69: 1240-1246. PMID 29128805 DOI: 10.1016/j.pharep.2017.05.009  0.84
2017 Ramos-Hryb AB, Pazini FL, Kaster MP, Rodrigues ALS. Therapeutic Potential of Ursolic Acid to Manage Neurodegenerative and Psychiatric Diseases. Cns Drugs. PMID 29098660 DOI: 10.1007/s40263-017-0474-4  0.84
2017 Moretti M, Fraga DB, Rodrigues ALS. Preventive and therapeutic potential of ascorbic acid in neurodegenerative diseases. Cns Neuroscience & Therapeutics. PMID 28980404 DOI: 10.1111/cns.12767  0.48
2017 Olescowicz G, Neis VB, Fraga DB, Rosa PB, Azevedo DP, Melleu FF, Brocardo PS, Gil-Mohapel J, Rodrigues ALS. Antidepressant and pro-neurogenic effects of agmatine in a mouse model of stress induced by chronic exposure to corticosterone. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28842257 DOI: 10.1016/j.pnpbp.2017.08.017  0.72
2017 Gonçalves FM, Neis VB, Rieger DK, Peres TV, Lopes MW, Heinrich IA, Costa AP, Rodrigues ALS, Kaster MP, Leal RB. Glutamatergic system and mTOR-signaling pathway participate in the antidepressant-like effect of inosine in the tail suspension test. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 28695335 DOI: 10.1007/s00702-017-1753-4  0.84
2017 Mazur FG, Oliveira LFG, Cunha MP, Rodrigues ALS, Pértile RAN, Vendruscolo LF, Izídio GS. Effects of physical exercise and social isolation on anxiety-related behaviors in two inbred rat strains. Behavioural Processes. 142: 70-78. PMID 28602748 DOI: 10.1016/j.beproc.2017.06.001  0.76
2017 Moretti M, Fraga DB, Rodrigues ALS. Ascorbic Acid to Manage Psychiatric Disorders. Cns Drugs. PMID 28600627 DOI: 10.1007/s40263-017-0446-8  0.48
2017 Neis VB, Rosa PB, Olescowicz G, Rodrigues ALS. Therapeutic potential of agmatine for CNS disorders. Neurochemistry International. PMID 28522414 DOI: 10.1016/j.neuint.2017.05.006  0.48
2017 Manosso LM, Moretti M, Rosa JM, Cunha MP, Rodrigues AL. Evidence for the involvement of heme oxygenase-1 in the antidepressant-like effect of zinc. Pharmacological Reports : Pr. 69: 497-503. PMID 28342333 DOI: 10.1016/j.pharep.2017.01.010  0.76
2017 Kaufmann FN, Costa AP, Ghisleni G, Diaz AP, Rodrigues AL, Peluffo H, Kaster MP. Nlrp3 Inflammasome-Driven Pathways In Depression: Clinical And Preclinical Findings. Brain, Behavior, and Immunity. PMID 28263786 DOI: 10.1016/j.bbi.2017.03.002  0.84
2017 Budni J, Molz S, Dal-Cim T, Martín-de-Saavedra MD, Egea J, Lopéz MG, Tasca CI, Rodrigues AL. Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS. Molecular Neurobiology. PMID 28185129 DOI: 10.1007/s12035-017-0425-6  0.64
2016 Gonçalves FM, Neis VB, Rieger DK, Lopes MW, Heinrich IA, Costa AP, Rodrigues AL, Kaster MP, Leal RB. Signaling pathways underlying the antidepressant-like effect of inosine in mice. Purinergic Signalling. PMID 27966087 DOI: 10.1007/s11302-016-9551-2  0.84
2016 Bettio LE, Gil-Mohapel J, Rodrigues AL. Current perspectives on the antidepressant-like effects of guanosine. Neural Regeneration Research. 11: 1411-1413. PMID 27857738 DOI: 10.4103/1673-5374.191209  0.72
2016 Freitas AE, Neis VB, Rodrigues AL. Agmatine, a potential novel therapeutic strategy for depression. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27836390 DOI: 10.1016/j.euroneuro.2016.10.013  0.44
2016 Lieberknecht V, Cunha MP, Junqueira SC, Coelho ID, de Souza LF, Dos Santos AR, Rodrigues AL, Dutra RC, Dafre AL. Antidepressant-like effect of pramipexole in an inflammatory model of depression. Behavioural Brain Research. PMID 27825895 DOI: 10.1016/j.bbr.2016.11.007  0.76
2016 Neis VB, Bettio LE, Moretti M, Rosa PB, Ribeiro CM, Freitas AE, Gonçalves FM, Leal RB, Rodrigues AL. Acute agmatine administration, similar to ketamine, reverses depressive-like behavior induced by chronic unpredictable stress in mice. Pharmacology, Biochemistry, and Behavior. PMID 27743829 DOI: 10.1016/j.pbb.2016.10.004  0.56
2016 Cunha MP, Pazini FL, Lieberknecht V, Budni J, Oliveira Á, Rosa JM, Mancini G, Mazzardo L, Colla AR, Leite MC, Santos AR, Martins DF, de Bem AF, Gonçalves CA, Farina M, ... Rodrigues AL, et al. MPP(+)-Lesioned Mice: an Experimental Model of Motor, Emotional, Memory/Learning, and Striatal Neurochemical Dysfunctions. Molecular Neurobiology. PMID 27722926 DOI: 10.1007/s12035-016-0147-1  0.84
2016 Moretti M, Budni J, Ribeiro CM, Rieger DK, Leal RB, Rodrigues AL. Subchronic administration of ascorbic acid elicits antidepressant-like effect and modulates cell survival signaling pathways in mice. The Journal of Nutritional Biochemistry. 38: 50-56. PMID 27721116 DOI: 10.1016/j.jnutbio.2016.09.004  0.64
2016 Pazini FL, Cunha MP, Azevedo D, Rosa JM, Colla A, de Oliveira J, Ramos-Hryb AB, Brocardo PS, Gil-Mohapel J, Rodrigues AL. Creatine Prevents Corticosterone-Induced Reduction in Hippocampal Proliferation and Differentiation: Possible Implication for Its Antidepressant Effect. Molecular Neurobiology. PMID 27714631 DOI: 10.1007/s12035-016-0148-0  0.84
2016 Ludka FK, Cunha MP, Dal-Cim T, Binder LB, Constantino LC, Massari CM, Martins WC, Rodrigues AL, Tasca CI. Atorvastatin Protects from Aβ1-40-Induced Cell Damage and Depressive-Like Behavior via ProBDNF Cleavage. Molecular Neurobiology. PMID 27709490 DOI: 10.1007/s12035-016-0134-6  0.76
2016 Ludka FK, Constantino LC, Dal-Cim T, Binder LB, Zomkowski A, Rodrigues AL, Tasca CI. Involvement of PI3K/Akt/GSK-3β and mTOR in the antidepressant-like effect of atorvastatin in mice. Journal of Psychiatric Research. 82: 50-57. PMID 27468164 DOI: 10.1016/j.jpsychires.2016.07.004  0.56
2016 Rosa PB, Neis VB, Ribeiro CM, Moretti M, Rodrigues AL. Antidepressant-like effects of ascorbic acid and ketamine involve modulation of GABAA and GABAB receptors. Pharmacological Reports : Pr. 68: 996-1001. PMID 27423525 DOI: 10.1016/j.pharep.2016.05.010  0.48
2016 Bettio LE, Patten AR, Gil-Mohapel J, O'Rourke NF, Hanley RP, Kennedy S, Gopalakrishnan K, Rodrigues AL, Wulff J, Christie BR. ISX-9 can potentiate cell proliferation and neuronal commitment in the rat dentate gyrus. Neuroscience. PMID 27373772 DOI: 10.1016/j.neuroscience.2016.06.042  0.72
2016 Cunha AS, Matheus FC, Moretti M, Sampaio TB, Poli A, Santos DB, Colle D, Cunha MP, Blum-Silva CH, Sandjo LP, Reginatto FH, Rodrigues AL, Farina M, Prediger RD. Agmatine attenuates reserpine-induced oral dyskinesia in mice: Role of oxidative stress, nitric oxide and glutamate NMDA receptors. Behavioural Brain Research. PMID 27306571 DOI: 10.1016/j.bbr.2016.06.014  0.76
2016 Engel DF, de Oliveira J, Lopes JB, Santos DB, Moreira EL, Farina M, Rodrigues AL, de Souza Brocardo P, de Bem AF. Is there an association between hypercholesterolemia and depression? Behavioral evidence from the LDLr(-/-) mouse experimental model. Behavioural Brain Research. PMID 27185735 DOI: 10.1016/j.bbr.2016.05.029  0.72
2016 Junqueira SC, Dos Santos Coelho I, Lieberknecht V, Cunha MP, Calixto JB, Rodrigues AL, Santos AR, Dutra RC. Inosine, an Endogenous Purine Nucleoside, Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis: a Role for A2A Adenosine Receptor. Molecular Neurobiology. PMID 27130268 DOI: 10.1007/s12035-016-9893-3  0.48
2016 Neis VB, Moretti M, Bettio LE, Ribeiro CM, Rosa PB, Gonçalves FM, Lopes MW, Leal RB, Rodrigues AL. Agmatine produces antidepressant-like effects by activating AMPA receptors and mTOR signaling. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27061850 DOI: 10.1016/j.euroneuro.2016.03.009  0.56
2016 Bettio LE, Gil-Mohapel J, Rodrigues AL. Guanosine and its role in neuropathologies. Purinergic Signalling. PMID 27002712 DOI: 10.1007/s11302-016-9509-4  0.72
2016 Cunha MP, Lieberknecht V, Ramos-Hryb AB, Olescowicz G, Ludka FK, Tasca CI, Gabilan NH, Rodrigues AL. Creatine affords protection against glutamate-induced nitrosative and oxidative stress. Neurochemistry International. PMID 26804444 DOI: 10.1016/j.neuint.2016.01.002  0.48
2016 Lieberknecht V, Junqueira SC, Cunha MP, Barbosa TA, de Souza LF, Coelho IS, Santos AR, Rodrigues AL, Dafré AL, Dutra RC. Pramipexole, a Dopamine D2/D3 Receptor-Preferring Agonist, Prevents Experimental Autoimmune Encephalomyelitis Development in Mice. Molecular Neurobiology. PMID 26801190 DOI: 10.1007/s12035-016-9717-5  0.48
2016 Bettio LE, Neis VB, Pazini FL, Brocardo PS, Patten AR, Gil-Mohapel J, Christie BR, Rodrigues AL. The antidepressant-like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation. The European Journal of Neuroscience. PMID 26779605 DOI: 10.1111/ejn.13172  0.48
2016 Manosso LM, Moretti M, Colla AR, Ribeiro CM, Dal-Cim T, Tasca CI, Rodrigues AL. Involvement of glutamatergic neurotransmission in the antidepressant-like effect of zinc in the chronic unpredictable stress model of depression. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 26747027 DOI: 10.1007/s00702-015-1504-3  0.48
2015 Kaster MP, Moretti M, Cunha MP, Rodrigues AL. Novel approaches for the management of depressive disorders. European Journal of Pharmacology. PMID 26703867 DOI: 10.1016/j.ejphar.2015.12.029  0.48
2015 Pazini FL, Cunha MP, Rosa JM, Colla AR, Lieberknecht V, Oliveira Á, Rodrigues AL. Creatine, Similar to Ketamine, Counteracts Depressive-Like Behavior Induced by Corticosterone via PI3K/Akt/mTOR Pathway. Molecular Neurobiology. PMID 26660117 DOI: 10.1007/s12035-015-9580-9  0.48
2015 Moretti M, Neis VB, Matheus FC, Cunha MP, Rosa PB, Ribeiro CM, Rodrigues AL, Prediger RD. Effects of Agmatine on Depressive-Like Behavior Induced by Intracerebroventricular Administration of 1-Methyl-4-phenylpyridinium (MPP(+)). Neurotoxicity Research. 28: 222-31. PMID 26156429 DOI: 10.1007/s12640-015-9540-1  0.76
2015 Nascimento FP, Macedo-Júnior SJ, Borges FR, Cremonese RP, da Silva MD, Luiz-Cerutti M, Martins DF, Rodrigues AL, Santos AR. Thalidomide reduces mechanical hyperalgesia and depressive-like behavior induced by peripheral nerve crush in mice. Neuroscience. 303: 51-8. PMID 26126925 DOI: 10.1016/j.neuroscience.2015.06.044  0.44
2015 Kaster MP, Machado NJ, Silva HB, Nunes A, Ardais AP, Santana M, Baqi Y, Müller CE, Rodrigues AL, Porciúncula LO, Chen JF, Tomé ÂR, Agostinho P, Canas PM, Cunha RA. Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress. Proceedings of the National Academy of Sciences of the United States of America. 112: 7833-8. PMID 26056314 DOI: 10.1073/pnas.1423088112  0.84
2015 Freitas AE, Egea J, Buendia I, Gómez-Rangel V, Parada E, Navarro E, Casas AI, Wojnicz A, Ortiz JA, Cuadrado A, Ruiz-Nuño A, Rodrigues AL, Lopez MG. Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice. Molecular Neurobiology. PMID 25966970 DOI: 10.1007/s12035-015-9182-6  0.6
2015 Cunha MP, Budni J, Ludka FK, Pazini FL, Rosa JM, Oliveira Á, Lopes MW, Tasca CI, Leal RB, Rodrigues AL. Involvement of PI3K/Akt Signaling Pathway and Its Downstream Intracellular Targets in the Antidepressant-Like Effect of Creatine. Molecular Neurobiology. PMID 25943184 DOI: 10.1007/s12035-015-9192-4  0.76
2015 Colla AR, Rosa JM, Cunha MP, Rodrigues AL. Anxiolytic-like effects of ursolic acid in mice. European Journal of Pharmacology. 758: 171-6. PMID 25861934 DOI: 10.1016/j.ejphar.2015.03.077  0.76
2015 Moretti M, Budni J, Freitas AE, Neis VB, Ribeiro CM, de Oliveira Balen G, Rieger DK, Leal RB, Rodrigues AL. TNF-α-induced depressive-like phenotype and p38(MAPK) activation are abolished by ascorbic acid treatment. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 902-12. PMID 25836357 DOI: 10.1016/j.euroneuro.2015.03.006  0.64
2015 Cunha MP, Pazini FL, Rosa JM, Ramos-Hryb AB, Oliveira Á, Kaster MP, Rodrigues AL. Creatine, similarly to ketamine, affords antidepressant-like effects in the tail suspension test via adenosine A₁ and A2A receptor activation. Purinergic Signalling. 11: 215-27. PMID 25702084 DOI: 10.1007/s11302-015-9446-7  0.76
2015 Vandresen-Filho S, França LM, Alcantara-Junior J, Nogueira LC, de Brito TM, Lopes L, Junior FM, Vanzeler ML, Bertoldo DB, Dias PG, Colla AR, Hoeller A, Duzzioni M, Rodrigues AL, de Lima TC, et al. Statins enhance cognitive performance in object location test in albino Swiss mice: involvement of beta-adrenoceptors. Physiology & Behavior. 143: 27-34. PMID 25700896 DOI: 10.1016/j.physbeh.2015.02.024  0.76
2015 Manosso LM, Moretti M, Ribeiro CM, Gonçalves FM, Leal RB, Rodrigues AL. Antidepressant-like effect of zinc is dependent on signaling pathways implicated in BDNF modulation. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 59: 59-67. PMID 25600102 DOI: 10.1016/j.pnpbp.2015.01.008  0.76
2015 Cunha MP, Pazini FL, Ludka FK, Rosa JM, Oliveira Á, Budni J, Ramos-Hryb AB, Lieberknecht V, Bettio LE, Martín-de-Saavedra MD, López MG, Tasca CI, Rodrigues AL. The modulation of NMDA receptors and L-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test. Amino Acids. 47: 795-811. PMID 25555469 DOI: 10.1007/s00726-014-1910-0  0.76
2015 Neis VB, Moretti M, Manosso LM, Lopes MW, Leal RB, Rodrigues AL. Agmatine enhances antidepressant potency of MK-801 and conventional antidepressants in mice. Pharmacology, Biochemistry, and Behavior. 130: 9-14. PMID 25553821 DOI: 10.1016/j.pbb.2014.12.009  0.56
2015 Freitas AE, Egea J, Buendía I, Navarro E, Rada P, Cuadrado A, Rodrigues AL, López MG. Agmatine induces Nrf2 and protects against corticosterone effects in hippocampal neuronal cell line. Molecular Neurobiology. 51: 1504-19. PMID 25084759 DOI: 10.1007/s12035-014-8827-1  0.76
2015 Kaster MP, Machado NJ, Silva HB, Nunes A, Ardais AP, Santana M, Baqi Y, Müller CE, Rodrigues ALS, Porciúncula LO, Chen JF, Tomé ÂR, Agostinho P, Canas PM, Cunha RA. Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress Proceedings of the National Academy of Sciences of the United States of America. 112: 7833-7838. DOI: 10.1073/pnas.1423088112  0.76
2015 Freitas AE, Egea J, Buendia I, Gómez-Rangel V, Parada E, Navarro E, Casas AI, Wojnicz A, Ortiz JA, Cuadrado A, Ruiz-Nuño A, Rodrigues ALS, Lopez MG. Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice Molecular Neurobiology. DOI: 10.1007/s12035-015-9182-6  0.76
2014 De Bem A, Engel D, de Oliveira J, Moreira EL, Neis VB, Santos DB, Lopes JB, Rodrigues AL, Brocardo P. Hypercholesterolemia as a risk factor for depressive disorder? Free Radical Biology & Medicine. 75: S28. PMID 26461327 DOI: 10.1016/j.freeradbiomed.2014.10.753  0.44
2014 Cunha MP, Martín-de-Saavedra MD, Romero A, Egea J, Ludka FK, Tasca CI, Farina M, Rodrigues AL, López MG. Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson's model. Asn Neuro. 6. PMID 25424428 DOI: 10.1177/1759091414554945  0.76
2014 Rieger DK, Cunha RM, Lopes MW, Costa AP, Budni J, Rodrigues AL, Walz R, Teixeira EH, Nascimento KS, Cavada BS, Leal RB. ConBr, a lectin from Canavalia brasiliensis seeds, modulates signaling pathways and increases BDNF expression probably via a glycosylated target. Journal of Molecular Recognition : Jmr. 27: 746-54. PMID 25319623 DOI: 10.1002/jmr.2401  0.76
2014 Bettio LE, Freitas AE, Neis VB, Santos DB, Ribeiro CM, Rosa PB, Farina M, Rodrigues AL. Guanosine prevents behavioral alterations in the forced swimming test and hippocampal oxidative damage induced by acute restraint stress. Pharmacology, Biochemistry, and Behavior. 127: 7-14. PMID 25316306 DOI: 10.1016/j.pbb.2014.10.002  0.72
2014 Rosa PB, Ribeiro CM, Bettio LE, Colla A, Lieberknecht V, Moretti M, Rodrigues AL. Folic acid prevents depressive-like behavior induced by chronic corticosterone treatment in mice. Pharmacology, Biochemistry, and Behavior. 127: 1-6. PMID 25316305 DOI: 10.1016/j.pbb.2014.10.003  0.6
2014 Freitas AE, Bettio LE, Neis VB, Moretti M, Ribeiro CM, Lopes MW, Leal RB, Rodrigues AL. Sub-chronic agmatine treatment modulates hippocampal neuroplasticity and cell survival signaling pathways in mice. Journal of Psychiatric Research. 58: 137-46. PMID 25161097 DOI: 10.1016/j.jpsychires.2014.07.024  0.56
2014 Cunha MP, Budni J, Pazini FL, Oliveira Á, Rosa JM, Lopes MW, Leal RB, Rodrigues AL. Involvement of PKA, PKC, CAMK-II and MEK1/2 in the acute antidepressant-like effect of creatine in mice. Pharmacological Reports : Pr. 66: 653-9. PMID 24948068 DOI: 10.1016/j.pharep.2014.03.004  0.76
2014 Moretti M, Matheus FC, de Oliveira PA, Neis VB, Ben J, Walz R, Rodrigues AL, Prediger RD. Role of agmatine in neurodegenerative diseases and epilepsy. Frontiers in Bioscience (Elite Edition). 6: 341-59. PMID 24896210  0.76
2014 Colla AR, Oliveira A, Pazini FL, Rosa JM, Manosso LM, Cunha MP, Rodrigues AL. Serotonergic and noradrenergic systems are implicated in the antidepressant-like effect of ursolic acid in mice. Pharmacology, Biochemistry, and Behavior. 124: 108-16. PMID 24887451 DOI: 10.1016/j.pbb.2014.05.015  0.76
2014 Ludka FK, Constantino LC, Kuminek G, Binder LB, Zomkowski AD, Cunha MP, Dal-Cim T, Rodrigues AL, Tasca CI. Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice. Pharmacology, Biochemistry, and Behavior. 122: 253-60. PMID 24769309 DOI: 10.1016/j.pbb.2014.04.005  0.76
2014 Rieger DK, Costa AP, Budni J, Moretti M, Barbosa SG, Nascimento KS, Teixeira EH, Cavada BS, Rodrigues AL, Leal RB. Antidepressant-like effect of Canavalia brasiliensis (ConBr) lectin in mice: evidence for the involvement of the glutamatergic system. Pharmacology, Biochemistry, and Behavior. 122: 53-60. PMID 24650588 DOI: 10.1016/j.pbb.2014.03.008  0.64
2014 de Rezende VB, Rosa DV, Comim CM, Magno LA, Rodrigues AL, Vidigal P, Jeromin A, Quevedo J, Romano-Silva MA. NCS-1 deficiency causes anxiety and depressive-like behavior with impaired non-aversive memory in mice. Physiology & Behavior. 130: 91-8. PMID 24631552 DOI: 10.1016/j.physbeh.2014.03.005  0.76
2014 Neis VB, Manosso LM, Moretti M, Freitas AE, Daufenbach J, Rodrigues AL. Depressive-like behavior induced by tumor necrosis factor-α is abolished by agmatine administration. Behavioural Brain Research. 261: 336-44. PMID 24406719 DOI: 10.1016/j.bbr.2013.12.038  0.52
2014 Freitas AE, Bettio LE, Neis VB, Santos DB, Ribeiro CM, Rosa PB, Farina M, Rodrigues AL. Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 50: 143-50. PMID 24370459 DOI: 10.1016/j.pnpbp.2013.12.012  0.72
2014 Moretti M, Budni J, Freitas AE, Rosa PB, Rodrigues AL. Antidepressant-like effect of ascorbic acid is associated with the modulation of mammalian target of rapamycin pathway. Journal of Psychiatric Research. 48: 16-24. PMID 24209999 DOI: 10.1016/j.jpsychires.2013.10.014  0.64
2014 Vasconcelos MA, Arruda FVS, Santos HS, Rodrigues AS, Bandeira PN, Albuquerque MRJR, Cavada BS, Teixeira EH, Henriques M, Pereira MO. Effect of a casbane diterpene isolated from Croton nepetaefolius on the prevention and control of biofilms formed by bacteria and Candida species Industrial Crops and Products. 61: 499-509. DOI: 10.1016/j.indcrop.2014.07.027  0.4
2013 Freitas AE, Moretti M, Budni J, Balen GO, Fernandes SC, Veronezi PO, Heller M, Micke GA, Pizzolatti MG, Rodrigues AL. NMDA receptors and the L-arginine-nitric oxide-cyclic guanosine monophosphate pathway are implicated in the antidepressant-like action of the ethanolic extract from Tabebuia avellanedae in mice. Journal of Medicinal Food. 16: 1030-8. PMID 24236576 DOI: 10.1089/jmf.2012.0276  0.64
2013 Manosso LM, Moretti M, Rodrigues AL. Nutritional strategies for dealing with depression. Food & Function. 4: 1776-93. PMID 24154759 DOI: 10.1039/c3fo60246j  0.52
2013 Gonçalves FM, Freitas AE, Peres TV, Rieger DK, Ben J, Maestri M, Costa AP, Tramontina AC, Gonçalves CA, Rodrigues AL, Nagano CS, Teixeira EH, Nascimento KS, Cavada BS, Leal RB. Vatairea macrocarpa lectin (VML) induces depressive-like behavior and expression of neuroinflammatory markers in mice. Neurochemical Research. 38: 2375-84. PMID 24026569 DOI: 10.1007/s11064-013-1150-9  0.56
2013 Rosa JM, Dafre AL, Rodrigues AL. Antidepressant-like responses in the forced swimming test elicited by glutathione and redox modulation. Behavioural Brain Research. 253: 165-72. PMID 23850355 DOI: 10.1016/j.bbr.2013.07.009  0.76
2013 Manosso LM, Neis VB, Moretti M, Daufenbach JF, Freitas AE, Colla AR, Rodrigues AL. Antidepressant-like effect of α-tocopherol in a mouse model of depressive-like behavior induced by TNF-α. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 46: 48-57. PMID 23816813 DOI: 10.1016/j.pnpbp.2013.06.012  0.52
2013 Piletz JE, Aricioglu F, Cheng JT, Fairbanks CA, Gilad VH, Haenisch B, Halaris A, Hong S, Lee JE, Li J, Liu P, Molderings GJ, Rodrigues AL, Satriano J, Seong GJ, et al. Agmatine: clinical applications after 100 years in translation. Drug Discovery Today. 18: 880-93. PMID 23769988 DOI: 10.1016/j.drudis.2013.05.017  0.76
2013 Zeni AL, Zomkowski AD, Maraschin M, Tasca CI, Rodrigues AL. Evidence of the involvement of the monoaminergic systems in the antidepressant-like effect of Aloysia gratissima. Journal of Ethnopharmacology. 148: 914-20. PMID 23747494 DOI: 10.1016/j.jep.2013.05.042  0.56
2013 Martín-de-Saavedra MD, Budni J, Cunha MP, Gómez-Rangel V, Lorrio S, Del Barrio L, Lastres-Becker I, Parada E, Tordera RM, Rodrigues AL, Cuadrado A, López MG. Nrf2 participates in depressive disorders through an anti-inflammatory mechanism. Psychoneuroendocrinology. 38: 2010-22. PMID 23623252 DOI: 10.1016/j.psyneuen.2013.03.020  0.76
2013 Kaster MP, Budni J, Gazal M, Cunha MP, Santos AR, Rodrigues AL. The antidepressant-like effect of inosine in the FST is associated with both adenosine A1 and A 2A receptors. Purinergic Signalling. 9: 481-6. PMID 23613131 DOI: 10.1007/s11302-013-9361-8  0.76
2013 Dos Santos VV, Rodrigues AL, De Lima TC, de Barioglio SR, Raisman-Vozari R, Prediger RD. Ghrelin as a neuroprotective and palliative agent in Alzheimer's and Parkinson's disease. Current Pharmaceutical Design. 19: 6773-90. PMID 23530516  0.52
2013 Engel D, Zomkowski AD, Lieberknecht V, Rodrigues AL, Gabilan NH. Chronic administration of duloxetine and mirtazapine downregulates proapoptotic proteins and upregulates neurotrophin gene expression in the hippocampus and cerebral cortex of mice. Journal of Psychiatric Research. 47: 802-8. PMID 23522402 DOI: 10.1016/j.jpsychires.2013.02.013  0.76
2013 Cunha MP, Martín-de-Saavedra MD, Romero A, Parada E, Egea J, Del Barrio L, Rodrigues AL, López MG. Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: Involvement of intracellular signaling pathways. Neuroscience. 238: 185-94. PMID 23485810 DOI: 10.1016/j.neuroscience.2013.02.030  0.48
2013 dos Santos VV, Santos DB, Lach G, Rodrigues AL, Farina M, De Lima TC, Prediger RD. Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ(1-40)) administration in mice. Behavioural Brain Research. 244: 107-15. PMID 23396168 DOI: 10.1016/j.bbr.2013.01.039  0.76
2013 Cunha MP, Pazini FL, Oliveira Á, Bettio LE, Rosa JM, Machado DG, Rodrigues AL. The activation of α1-adrenoceptors is implicated in the antidepressant-like effect of creatine in the tail suspension test. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 44: 39-50. PMID 23357536 DOI: 10.1016/j.pnpbp.2013.01.014  0.76
2013 Cunha MP, Pazini FL, Oliveira Á, Machado DG, Rodrigues AL. Evidence for the involvement of 5-HT1A receptor in the acute antidepressant-like effect of creatine in mice. Brain Research Bulletin. 95: 61-9. PMID 23352985 DOI: 10.1016/j.brainresbull.2013.01.005  0.76
2013 Freitas AE, Machado DG, Budni J, Neis VB, Balen GO, Lopes MW, de Souza LF, Veronezi PO, Heller M, Micke GA, Pizzolatti MG, Dafre AL, Leal RB, Rodrigues AL. Antidepressant-like action of the bark ethanolic extract from Tabebuia avellanedae in the olfactory bulbectomized mice. Journal of Ethnopharmacology. 145: 737-45. PMID 23237932 DOI: 10.1016/j.jep.2012.11.040  0.64
2013 Cunha MP, Oliveira Á, Pazini FL, Machado DG, Bettio LE, Budni J, Aguiar AS, Martins DF, Santos AR, Rodrigues AL. The antidepressant-like effect of physical activity on a voluntary running wheel. Medicine and Science in Sports and Exercise. 45: 851-9. PMID 23190594 DOI: 10.1249/MSS.0b013e31827b23e6  0.76
2013 Budni J, Zomkowski AD, Engel D, Santos DB, dos Santos AA, Moretti M, Valvassori SS, Ornell F, Quevedo J, Farina M, Rodrigues AL. Folic acid prevents depressive-like behavior and hippocampal antioxidant imbalance induced by restraint stress in mice. Experimental Neurology. 240: 112-21. PMID 23142187 DOI: 10.1016/j.expneurol.2012.10.024  0.76
2013 Machado DG, Cunha MP, Neis VB, Balen GO, Colla A, Bettio LE, Oliveira A, Pazini FL, Dalmarco JB, Simionatto EL, Pizzolatti MG, Rodrigues AL. Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L. Food Chemistry. 136: 999-1005. PMID 23122155 DOI: 10.1016/j.foodchem.2012.09.028  0.76
2013 Moretti M, Budni J, Dos Santos DB, Antunes A, Daufenbach JF, Manosso LM, Farina M, Rodrigues AL. Protective effects of ascorbic acid on behavior and oxidative status of restraint-stressed mice. Journal of Molecular Neuroscience : Mn. 49: 68-79. PMID 23054587 DOI: 10.1007/s12031-012-9892-4  0.72
2013 Freitas AE, Machado DG, Budni J, Neis VB, Balen GO, Lopes MW, de Souza LF, Dafre AL, Leal RB, Rodrigues AL. Fluoxetine modulates hippocampal cell signaling pathways implicated in neuroplasticity in olfactory bulbectomized mice. Behavioural Brain Research. 237: 176-84. PMID 23018126 DOI: 10.1016/j.bbr.2012.09.035  0.64
2013 Ludka FK, Zomkowski AD, Cunha MP, Dal-Cim T, Zeni AL, Rodrigues AL, Tasca CI. Acute atorvastatin treatment exerts antidepressant-like effect in mice via the L-arginine-nitric oxide-cyclic guanosine monophosphate pathway and increases BDNF levels. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 400-12. PMID 22682406 DOI: 10.1016/j.euroneuro.2012.05.005  0.76
2012 Zomkowski AD, Engel D, Cunha MP, Gabilan NH, Rodrigues AL. The role of the NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of duloxetine in the forced swimming test. Pharmacology, Biochemistry, and Behavior. 103: 408-17. PMID 23010381 DOI: 10.1016/j.pbb.2012.09.011  0.76
2012 Zeni AL, Zomkowski AD, Maraschin M, Rodrigues AL, Tasca CI. Involvement of PKA, CaMKII, PKC, MAPK/ERK and PI3K in the acute antidepressant-like effect of ferulic acid in the tail suspension test. Pharmacology, Biochemistry, and Behavior. 103: 181-6. PMID 22960128 DOI: 10.1016/j.pbb.2012.08.020  0.56
2012 Machado DG, Cunha MP, Neis VB, Balen GO, Colla A, Grando J, Brocardo PS, Bettio LE, Capra JC, Rodrigues AL. Fluoxetine reverses depressive-like behaviors and increases hippocampal acetylcholinesterase activity induced by olfactory bulbectomy. Pharmacology, Biochemistry, and Behavior. 103: 220-9. PMID 22960127 DOI: 10.1016/j.pbb.2012.08.024  0.76
2012 Machado DG, Neis VB, Balen GO, Colla A, Cunha MP, Dalmarco JB, Pizzolatti MG, Prediger RD, Rodrigues AL. Antidepressant-like effect of ursolic acid isolated from Rosmarinus officinalis L. in mice: evidence for the involvement of the dopaminergic system. Pharmacology, Biochemistry, and Behavior. 103: 204-11. PMID 22940588 DOI: 10.1016/j.pbb.2012.08.016  0.76
2012 Colla AR, Machado DG, Bettio LE, Colla G, Magina MD, Brighente IM, Rodrigues AL. Involvement of monoaminergic systems in the antidepressant-like effect of Eugenia brasiliensis Lam. (Myrtaceae) in the tail suspension test in mice. Journal of Ethnopharmacology. 143: 720-31. PMID 22884868 DOI: 10.1016/j.jep.2012.07.038  0.48
2012 Kaster MP, Machado DG, Santos AR, Rodrigues AL. Involvement of NMDA receptors in the antidepressant-like action of adenosine. Pharmacological Reports : Pr. 64: 706-13. PMID 22814023  0.76
2012 Bettio LE, Cunha MP, Budni J, Pazini FL, Oliveira Á, Colla AR, Rodrigues AL. Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways. Behavioural Brain Research. 234: 137-48. PMID 22743004 DOI: 10.1016/j.bbr.2012.06.021  0.76
2012 Machado DG, Cunha MP, Neis VB, Balen GO, Colla AR, Grando J, Brocardo PS, Bettio LE, Dalmarco JB, Rial D, Prediger RD, Pizzolatti MG, Rodrigues AL. Rosmarinus officinalis L. hydroalcoholic extract, similar to fluoxetine, reverses depressive-like behavior without altering learning deficit in olfactory bulbectomized mice. Journal of Ethnopharmacology. 143: 158-69. PMID 22721880 DOI: 10.1016/j.jep.2012.06.017  0.76
2012 Cunha MP, Machado DG, Capra JC, Jacinto J, Bettio LE, Rodrigues AL. Antidepressant-like effect of creatine in mice involves dopaminergic activation. Journal of Psychopharmacology (Oxford, England). 26: 1489-501. PMID 22674968 DOI: 10.1177/0269881112447989  0.76
2012 Moretti M, Budni J, Ribeiro CM, Rodrigues AL. Involvement of different types of potassium channels in the antidepressant-like effect of ascorbic acid in the mouse tail suspension test. European Journal of Pharmacology. 687: 21-7. PMID 22575518 DOI: 10.1016/j.ejphar.2012.04.041  0.64
2012 Carlini VP, Machado DG, Buteler F, Ghersi M, Ponzio MF, Martini AC, Schiöth HB, de Cuneo MF, Rodrigues AL, de Barioglio SR. Acute ghrelin administration reverses depressive-like behavior induced by bilateral olfactory bulbectomy in mice. Peptides. 35: 160-5. PMID 22525660 DOI: 10.1016/j.peptides.2012.03.031  0.48
2012 Zeni AL, Zomkowski AD, Maraschin M, Rodrigues AL, Tasca CI. Ferulic acid exerts antidepressant-like effect in the tail suspension test in mice: evidence for the involvement of the serotonergic system. European Journal of Pharmacology. 679: 68-74. PMID 22266492 DOI: 10.1016/j.ejphar.2011.12.041  0.56
2012 Budni J, Freitas AE, Binfaré RW, Rodrigues AL. Role of potassium channels in the antidepressant-like effect of folic acid in the forced swimming test in mice. Pharmacology, Biochemistry, and Behavior. 101: 148-54. PMID 22227220 DOI: 10.1016/j.pbb.2011.12.008  0.64
2012 Budni J, Lobato KR, Binfaré RW, Freitas AE, Costa AP, Martín-de-Saavedra MD, Leal RB, Lopez MG, Rodrigues AL. Involvement of PI3K, GSK-3β and PPARγ in the antidepressant-like effect of folic acid in the forced swimming test in mice. Journal of Psychopharmacology (Oxford, England). 26: 714-23. PMID 22037925 DOI: 10.1177/0269881111424456  0.76
2012 Kaster MP, Gadotti VM, Calixto JB, Santos AR, Rodrigues AL. Depressive-like behavior induced by tumor necrosis factor-α in mice. Neuropharmacology. 62: 419-26. PMID 21867719 DOI: 10.1016/j.neuropharm.2011.08.018  0.76
2011 Bettio LE, Machado DG, Cunha MP, Capra JC, Missau FC, Santos AR, Pizzolatti MG, Rodrigues AL. Antidepressant-like effect of extract from Polygala paniculata: involvement of the monoaminergic systems. Pharmaceutical Biology. 49: 1277-85. PMID 22077163 DOI: 10.3109/13880209.2011.621958  0.76
2011 Moretti M, Freitas AE, Budni J, Fernandes SC, Balen Gde O, Rodrigues AL. Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test. Behavioural Brain Research. 225: 328-33. PMID 21802450 DOI: 10.1016/j.bbr.2011.07.024  0.64
2011 Zeni AL, Zomkowski AD, Dal-Cim T, Maraschin M, Rodrigues AL, Tasca CI. Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway. Journal of Ethnopharmacology. 137: 864-74. PMID 21767626 DOI: 10.1016/j.jep.2011.07.009  0.56
2011 Molz S, Dal-Cim T, Budni J, Martín-de-Saavedra MD, Egea J, Romero A, del Barrio L, Rodrigues AL, López MG, Tasca CI. Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition. Journal of Neuroscience Research. 89: 1400-8. PMID 21671255 DOI: 10.1002/jnr.22681  0.76
2011 Budni J, Romero A, Molz S, Martín-de-Saavedra MD, Egea J, Del Barrio L, Tasca CI, Rodrigues AL, López MG. Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid. Neuroscience. 190: 346-53. PMID 21640799 DOI: 10.1016/j.neuroscience.2011.05.053  0.76
2010 Zomkowski AD, Engel D, Gabilan NH, Rodrigues AL. Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effects of escitalopram in the forced swimming test. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 20: 793-801. PMID 20810255 DOI: 10.1016/j.euroneuro.2010.07.011  0.48
2010 Schwarzbold ML, Rial D, De Bem T, Machado DG, Cunha MP, dos Santos AA, dos Santos DB, Figueiredo CP, Farina M, Goldfeder EM, Rodrigues AL, Prediger RD, Walz R. Effects of traumatic brain injury of different severities on emotional, cognitive, and oxidative stress-related parameters in mice. Journal of Neurotrauma. 27: 1883-93. PMID 20649482 DOI: 10.1089/neu.2010.1318  0.76
2010 Brocardo PS, Budni J, Pavesi E, Franco JL, Uliano-Silva M, Trevisan R, Terenzi MG, Dafre AL, Rodrigues AL. Folic acid administration prevents ouabain-induced hyperlocomotion and alterations in oxidative stress markers in the rat brain. Bipolar Disorders. 12: 414-24. PMID 20636639 DOI: 10.1111/j.1399-5618.2010.00827.x  0.72
2010 Capra JC, Cunha MP, Machado DG, Zomkowski AD, Mendes BG, Santos AR, Pizzolatti MG, Rodrigues AL. Antidepressant-like effect of scopoletin, a coumarin isolated from Polygala sabulosa (Polygalaceae) in mice: evidence for the involvement of monoaminergic systems. European Journal of Pharmacology. 643: 232-8. PMID 20599906 DOI: 10.1016/j.ejphar.2010.06.043  0.76
2010 Nascimento FP, Figueredo SM, Marcon R, Martins DF, Macedo SJ, Lima DA, Almeida RC, Ostroski RM, Rodrigues AL, Santos AR. Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways. The Journal of Pharmacology and Experimental Therapeutics. 334: 590-8. PMID 20472668 DOI: 10.1124/jpet.110.166058  0.44
2010 Binfaré RW, Mantovani M, Budni J, Santos AR, Rodrigues AL. Involvement of dopamine receptors in the antidepressant-like effect of melatonin in the tail suspension test. European Journal of Pharmacology. 638: 78-83. PMID 20406627 DOI: 10.1016/j.ejphar.2010.04.011  0.64
2010 Lobato KR, Cardoso CC, Binfaré RW, Budni J, Wagner CL, Brocardo PS, de Souza LF, Brocardo C, Flesch S, Freitas AE, Dafré AL, Rodrigues AL. alpha-Tocopherol administration produces an antidepressant-like effect in predictive animal models of depression. Behavioural Brain Research. 209: 249-59. PMID 20144659 DOI: 10.1016/j.bbr.2010.02.002  0.72
2010 Freitas AE, Budni J, Lobato KR, Binfaré RW, Machado DG, Jacinto J, Veronezi PO, Pizzolatti MG, Rodrigues AL. Antidepressant-like action of the ethanolic extract from Tabebuia avellanedae in mice: evidence for the involvement of the monoaminergic system. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34: 335-43. PMID 20026371 DOI: 10.1016/j.pnpbp.2009.12.010  0.64
2009 Binfaré RW, Rosa AO, Lobato KR, Santos AR, Rodrigues AL. Ascorbic acid administration produces an antidepressant-like effect: evidence for the involvement of monoaminergic neurotransmission. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 33: 530-40. PMID 19439241 DOI: 10.1016/j.pnpbp.2009.02.003  0.64
2009 Franco JL, Posser T, Mattos JJ, Trevisan R, Brocardo PS, Rodrigues AL, Leal RB, Farina M, Marques MR, Bainy AC, Dafre AL. Zinc reverses malathion-induced impairment in antioxidant defenses. Toxicology Letters. 187: 137-43. PMID 19429256 DOI: 10.1016/j.toxlet.2009.02.015  0.72
2009 Machado DG, Bettio LE, Cunha MP, Capra JC, Dalmarco JB, Pizzolatti MG, Rodrigues AL. Antidepressant-like effect of the extract of Rosmarinus officinalis in mice: involvement of the monoaminergic system. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 33: 642-50. PMID 19286446 DOI: 10.1016/j.pnpbp.2009.03.004  0.76
2009 Lapa Fda R, Gadotti VM, Missau FC, Pizzolatti MG, Marques MC, Dafré AL, Farina M, Rodrigues AL, Santos AR. Antinociceptive properties of the hydroalcoholic extract and the flavonoid rutin obtained from Polygala paniculata L. in mice. Basic & Clinical Pharmacology & Toxicology. 104: 306-15. PMID 19281602 DOI: 10.1111/j.1742-7843.2008.00365.x  0.72
2009 Brocardo PS, Budni J, Lobato KR, Santos AR, Rodrigues AL. Evidence for the involvement of the opioid system in the antidepressant-like effect of folic acid in the mouse forced swimming test. Behavioural Brain Research. 200: 122-7. PMID 19162083 DOI: 10.1016/j.bbr.2009.01.004  0.72
2009 Cardoso CC, Lobato KR, Binfaré RW, Ferreira PK, Rosa AO, Santos AR, Rodrigues AL. Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 33: 235-42. PMID 19059299 DOI: 10.1016/j.pnpbp.2008.11.007  0.64
2009 Posser T, Kaster MP, Baraúna SC, Rocha JB, Rodrigues AL, Leal RB. Antidepressant-like effect of the organoselenium compound ebselen in mice: evidence for the involvement of the monoaminergic system. European Journal of Pharmacology. 602: 85-91. PMID 19026628 DOI: 10.1016/j.ejphar.2008.10.055  0.76
2008 Sabioni P, Baretta IP, Ninomiya EM, Gustafson L, Rodrigues AL, Andreatini R. The antimanic-like effect of tamoxifen: Behavioural comparison with other PKC-inhibiting and antiestrogenic drugs. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 1927-31. PMID 18930105 DOI: 10.1016/j.pnpbp.2008.09.023  0.56
2008 Cunha MP, Machado DG, Bettio LE, Capra JC, Rodrigues AL. Interaction of zinc with antidepressants in the tail suspension test. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 1913-20. PMID 18824054 DOI: 10.1016/j.pnpbp.2008.09.006  0.76
2008 Brocardo Pde S, Budni J, Lobato KR, Kaster MP, Rodrigues AL. Antidepressant-like effect of folic acid: Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway. European Journal of Pharmacology. 598: 37-42. PMID 18789921 DOI: 10.1016/j.ejphar.2008.08.033  0.76
2008 Ribas CM, Meotti FC, Nascimento FP, Jacques AV, Dafre AL, Rodrigues AL, Farina M, Soldi C, Mendes BG, Pizzolatti MG, Santos AR. Antinociceptive effect of the Polygala sabulosa hydroalcoholic extract in mice: evidence for the involvement of glutamatergic receptors and cytokine pathways. Basic & Clinical Pharmacology & Toxicology. 103: 43-7. PMID 18598298 DOI: 10.1111/j.1742-7843.2008.00245.x  0.72
2008 Rosa AO, Kaster MP, Binfaré RW, Morales S, Martín-Aparicio E, Navarro-Rico ML, Martinez A, Medina M, García AG, López MG, Rodrigues AL. Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 1549-56. PMID 18579278 DOI: 10.1016/j.pnpbp.2008.05.020  0.76
2008 Machado DG, Bettio LE, Cunha MP, Santos AR, Pizzolatti MG, Brighente IM, Rodrigues AL. Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: evidence for the involvement of the serotonergic and noradrenergic systems. European Journal of Pharmacology. 587: 163-8. PMID 18457827 DOI: 10.1016/j.ejphar.2008.03.021  0.76
2008 Trevisan R, Uliano-Silva M, Pandolfo P, Franco JL, Brocardo PS, Santos AR, Farina M, Rodrigues AL, Takahashi RN, Dafre AL. Antioxidant and acetylcholinesterase response to repeated malathion exposure in rat cerebral cortex and hippocampus. Basic & Clinical Pharmacology & Toxicology. 102: 365-9. PMID 18341513 DOI: 10.1111/j.1742-7843.2007.00182.x  0.76
2008 Lobato KR, Binfaré RW, Budni J, Rosa AO, Santos AR, Rodrigues AL. Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 994-9. PMID 18289757 DOI: 10.1016/j.pnpbp.2008.01.012  0.64
2008 Franco JL, Posser T, Brocardo PS, Trevisan R, Uliano-Silva M, Gabilan NH, Santos AR, Leal RB, Rodrigues AL, Farina M, Dafre AL. Involvement of glutathione, ERK1/2 phosphorylation and BDNF expression in the antidepressant-like effect of zinc in rats. Behavioural Brain Research. 188: 316-23. PMID 18191237 DOI: 10.1016/j.bbr.2007.11.012  0.72
2008 Brocardo PS, Budni J, Kaster MP, Santos AR, Rodrigues AL. Folic acid administration produces an antidepressant-like effect in mice: evidence for the involvement of the serotonergic and noradrenergic systems. Neuropharmacology. 54: 464-73. PMID 18078962 DOI: 10.1016/j.neuropharm.2007.10.016  0.76
2007 Luiz AP, Moura JD, Meotti FC, Guginski G, Guimarães CL, Azevedo MS, Rodrigues AL, Santos AR. Antinociceptive action of ethanolic extract obtained from roots of Humirianthera ampla Miers. Journal of Ethnopharmacology. 114: 355-63. PMID 17900839 DOI: 10.1016/j.jep.2007.08.016  0.44
2007 Kaster MP, Budni J, Santos AR, Rodrigues AL. Pharmacological evidence for the involvement of the opioid system in the antidepressant-like effect of adenosine in the mouse forced swimming test. European Journal of Pharmacology. 576: 91-8. PMID 17868670 DOI: 10.1016/j.ejphar.2007.08.026  0.76
2007 Budni J, Gadotti VM, Kaster MP, Santos AR, Rodrigues AL. Role of different types of potassium channels in the antidepressant-like effect of agmatine in the mouse forced swimming test. European Journal of Pharmacology. 575: 87-93. PMID 17761162 DOI: 10.1016/j.ejphar.2007.08.010  0.76
2007 Codagnone FT, Consoni FT, Rodrigues AL, Vital MA, Andreatini R. Veratrine blocks the lamotrigine-induced swimming increase and immobility decrease in the modified forced swimming test. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 1307-11. PMID 17619070 DOI: 10.1016/j.pnpbp.2007.05.017  0.56
2007 Paszcuk AF, Gadotti VM, Tibola D, Quintão NL, Rodrigues AL, Calixto JB, Santos AR. Anti-hypernociceptive properties of agmatine in persistent inflammatory and neuropathic models of pain in mice. Brain Research. 1159: 124-33. PMID 17573052 DOI: 10.1016/j.brainres.2007.04.050  0.76
2007 Zeidan MP, Zomkowski AD, Rosa AO, Rodrigues AL, Gabilan NH. Evidence for imidazoline receptors involvement in the agmatine antidepressant-like effect in the forced swimming test. European Journal of Pharmacology. 565: 125-31. PMID 17445795 DOI: 10.1016/j.ejphar.2007.03.027  0.52
2007 Kaster MP, Raupp I, Binfaré RW, Andreatini R, Rodrigues AL. Antidepressant-like effect of lamotrigine in the mouse forced swimming test: evidence for the involvement of the noradrenergic system. European Journal of Pharmacology. 565: 119-24. PMID 17433291 DOI: 10.1016/j.ejphar.2007.03.003  0.76
2007 Brocardo PS, Assini F, Franco JL, Pandolfo P, Müller YM, Takahashi RN, Dafre AL, Rodrigues AL. Zinc attenuates malathion-induced depressant-like behavior and confers neuroprotection in the rat brain. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 140-8. PMID 17327255 DOI: 10.1093/toxsci/kfm024  0.76
2007 Kaster MP, Budni J, Binfaré RW, Santos AR, Rodrigues AL. The inhibition of different types of potassium channels underlies the antidepressant-like effect of adenosine in the mouse forced swimming test. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 690-6. PMID 17296254 DOI: 10.1016/j.pnpbp.2006.12.018  0.76
2007 Machado DG, Kaster MP, Binfaré RW, Dias M, Santos AR, Pizzolatti MG, Brighente IM, Rodrigues AL. Antidepressant-like effect of the extract from leaves of Schinus molle L. in mice: evidence for the involvement of the monoaminergic system. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 421-8. PMID 17182164 DOI: 10.1016/j.pnpbp.2006.11.004  0.76
2006 Mantovani M, Kaster MP, Pertile R, Calixto JB, Rodrigues AL, Santos AR. Mechanisms involved in the antinociception caused by melatonin in mice. Journal of Pineal Research. 41: 382-9. PMID 17014696 DOI: 10.1111/j.1600-079X.2006.00380.x  0.76
2006 Barauna SC, Kaster MP, Heckert BT, do Nascimento KS, Rossi FM, Teixeira EH, Cavada BS, Rodrigues AL, Leal RB. Antidepressant-like effect of lectin from Canavalia brasiliensis (ConBr) administered centrally in mice. Pharmacology, Biochemistry, and Behavior. 85: 160-9. PMID 16950503 DOI: 10.1016/j.pbb.2006.07.030  0.76
2006 Zomkowski AD, Santos AR, Rodrigues AL. Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 30: 1419-25. PMID 16822602 DOI: 10.1016/j.pnpbp.2006.05.016  0.44
2006 Gadotti VM, Tibola D, Paszcuk AF, Rodrigues AL, Calixto JB, Santos AR. Contribution of spinal glutamatergic receptors to the antinociception caused by agmatine in mice. Brain Research. 1093: 116-22. PMID 16765330 DOI: 10.1016/j.brainres.2006.03.087  0.76
2006 Meotti FC, Rosa JM, Brocardo PS, Balz D, Waltrick AP, Bagio A, Goulart EC, Dafre AL, Rodrigues AL, Santos AR. Protective effect of crude extract from Wedelia paludosa (Asteraceae) on the hepatotoxicity induced by paracetamol in mice. The Journal of Pharmacy and Pharmacology. 58: 137-42. PMID 16393474 DOI: 10.1211/jpp.58.1.0017  0.76
2006 Almeida RC, Felisbino CS, López MG, Rodrigues AL, Gabilan NH. Evidence for the involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice. Behavioural Brain Research. 168: 318-22. PMID 16387371 DOI: 10.1016/j.bbr.2005.11.023  0.48
2006 Almeida RC, Souza DG, Soletti RC, López MG, Rodrigues AL, Gabilan NH. Involvement of PKA, MAPK/ERK and CaMKII, but not PKC in the acute antidepressant-like effect of memantine in mice. Neuroscience Letters. 395: 93-7. PMID 16289784 DOI: 10.1016/j.neulet.2005.10.057  0.76
2005 Assini FL, Zanette KD, Brocardo PS, Pandolfo P, Rodrigues AL, Takahashi RN. Behavioral effects and ChE measures after acute and repeated administration of malathion in rats. Environmental Toxicology and Pharmacology. 20: 443-9. PMID 21783624 DOI: 10.1016/j.etap.2005.05.007  0.76
2005 Kaster MP, Rosa AO, Santos AR, Rodrigues AL. Involvement of nitric oxide-cGMP pathway in the antidepressant-like effects of adenosine in the forced swimming test. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 8: 601-6. PMID 16202183 DOI: 10.1017/S1461145705005316  0.76
2005 Rodrigues AL, Rosa JM, Gadotti VM, Goulart EC, Santos MM, Silva AV, Sehnem B, Rosa LS, Gonçalves RM, Corrêa R, Santos AR. Antidepressant-like and antinociceptive-like actions of 4-(4'-chlorophenyl)-6-(4''-methylphenyl)-2-hydrazinepyrimidine Mannich base in mice. Pharmacology, Biochemistry, and Behavior. 82: 156-62. PMID 16153700 DOI: 10.1016/j.pbb.2005.08.003  0.76
2005 Kaster MP, Santos AR, Rodrigues AL. Involvement of 5-HT1A receptors in the antidepressant-like effect of adenosine in the mouse forced swimming test. Brain Research Bulletin. 67: 53-61. PMID 16140163 DOI: 10.1016/j.brainresbull.2005.05.025  0.76
2005 Kaster MP, Ferreira PK, Santos AR, Rodrigues AL. Effects of potassium channel inhibitors in the forced swimming test: possible involvement of L-arginine-nitric oxide-soluble guanylate cyclase pathway. Behavioural Brain Research. 165: 204-9. PMID 16122818 DOI: 10.1016/j.bbr.2005.06.031  0.76
2005 Zomkowski AD, Santos AR, Rodrigues AL. Evidence for the involvement of the opioid system in the agmatine antidepressant-like effect in the forced swimming test. Neuroscience Letters. 381: 279-83. PMID 15896484 DOI: 10.1016/j.neulet.2005.02.026  0.44
2005 Rosa KA, Gadotti VM, Rosa AO, Rodrigues AL, Calixto JB, Santos AR. Evidence for the involvement of glutamatergic system in the antinociceptive effect of ascorbic acid. Neuroscience Letters. 381: 185-8. PMID 15882814 DOI: 10.1016/j.neulet.2005.02.032  0.76
2005 Santos AR, Gadotti VM, Oliveira GL, Tibola D, Paszcuk AF, Neto A, Spindola HM, Souza MM, Rodrigues AL, Calixto JB. Mechanisms involved in the antinociception caused by agmatine in mice. Neuropharmacology. 48: 1021-34. PMID 15857629 DOI: 10.1016/j.neuropharm.2005.01.012  0.76
2005 Brocardo PS, Pandolfo P, Takahashi RN, Rodrigues AL, Dafre AL. Antioxidant defenses and lipid peroxidation in the cerebral cortex and hippocampus following acute exposure to malathion and/or zinc chloride. Toxicology. 207: 283-91. PMID 15596258 DOI: 10.1016/j.tox.2004.09.012  0.76
2004 Kaster MP, Rosa AO, Rosso MM, Goulart EC, Santos AR, Rodrigues AL. Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors. Neuroscience Letters. 355: 21-4. PMID 14729225 DOI: 10.1016/j.neulet.2003.10.040  0.76
2004 Cordova FM, Rodrigues AL, Giacomelli MB, Oliveira CS, Posser T, Dunkley PR, Leal RB. Lead stimulates ERK1/2 and p38MAPK phosphorylation in the hippocampus of immature rats. Brain Research. 998: 65-72. PMID 14725969  0.56
2003 Rosa AO, Lin J, Calixto JB, Santos AR, Rodrigues AL. Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice. Behavioural Brain Research. 144: 87-93. PMID 12946598 DOI: 10.1016/S0166-4328(03)00069-X  0.76
2003 Mantovani M, Pértile R, Calixto JB, Santos AR, Rodrigues AL. Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway. Neuroscience Letters. 343: 1-4. PMID 12749983 DOI: 10.1016/S0304-3940(03)00306-9  0.76
2002 Gondran M, Eckeli AL, Migues PV, Gabilan NH, Rodrigues AL. The crude extract from the sea anemone, Bunodosoma caissarum elicits convulsions in mice: possible involvement of the glutamatergic system. Toxicon : Official Journal of the International Society On Toxinology. 40: 1667-74. PMID 12457877  0.48
2002 Zomkowski AD, Hammes L, Lin J, Calixto JB, Santos AR, Rodrigues AL. Agmatine produces antidepressant-like effects in two models of depression in mice. Neuroreport. 13: 387-91. PMID 11930146  0.44
2002 Rodrigues AL, da Silva GL, Mateussi AS, Fernandes ES, Miguel OG, Yunes RA, Calixto JB, Santos AR. Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus. Life Sciences. 70: 1347-58. PMID 11885577  0.44
2001 Goulart EC, Pereira CA, Garcia RC, Giacomelli MB, Rodrigues AL. Effects of lead and/or zinc exposure during the second stage of rapid postnatal brain growth on delta-aminolevulinate dehydratase and negative geotaxis of suckling rats. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 34: 785-90. PMID 11378669  0.52
2000 da Silva GD, Matteussi AS, dos Santos AR, Calixto JB, Rodrigues AL. Evidence for dual effects of nitric oxide in the forced swimming test and in the tail suspension test in mice. Neuroreport. 11: 3699-702. PMID 11117475  0.36
1999 Rodrigues AL, Regner A, Rubin MA, Souza DO. Effects of lead on adenylate cyclase activity in rat cerebral cortex. Neurochemical Research. 24: 1037-42. PMID 10478943  0.44
1998 Mello CF, Kraemer CK, Filippin A, Morsch VM, Rodrigues AL, Martins AF, Rubin MA. Effect of lead acetate on neurobehavioral development of rats. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 31: 943-50. PMID 9698759  0.44
1998 Beirith A, Santos AR, Rodrigues AL, Creczynski-Pasa TB, Calixto JB. Spinal and supraspinal antinociceptive action of dipyrone in formalin, capsaicin and glutamate tests. Study of the mechanism of action. European Journal of Pharmacology. 345: 233-45. PMID 9592021  0.44
1996 Rodrigues AL, Rocha JB, Mello CF, Souza DO. Effect of perinatal lead exposure on rat behaviour in open-field and two-way avoidance tasks. Pharmacology & Toxicology. 79: 150-6. PMID 8884874  0.44
1996 Rodrigues AL, Rocha JB, Pereira ME, Souza DO. Delta-aminolevulinic acid dehydratase activity in weanling and adult rats exposed to lead acetate. Bulletin of Environmental Contamination and Toxicology. 57: 47-53. PMID 8661459  0.44
1993 Rodrigues AL, Rubin MA, Souza DO, de Mello CF. Lead exposure and latent learning ability of adult female rats. Behavioral and Neural Biology. 60: 274-9. PMID 8297324  0.44
Show low-probability matches.