Adair Roberto Soares Santos - Publications

Affiliations: 
Physiology Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil 
Area:
nociception

178 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Macedo-Júnior SJ, Nascimento FP, Luiz-Cerutti M, Santos ARS. The role of peripheral adenosine receptors in glutamate-induced pain nociceptive behavior. Purinergic Signalling. PMID 33860899 DOI: 10.1007/s11302-021-09781-y  0.36
2021 Martins-Silva C, de Souza Pinho N, Ferreira GG, Aguiar RM, Ferreira TA, Pires RGW, Tizziani T, Pizzolatti MG, Santos ARS. Polygala sabulosa A.W. Bennett extract mitigates motor and cognitive deficits in a mouse model of acute ischemia. Metabolic Brain Disease. PMID 33394286 DOI: 10.1007/s11011-020-00660-w  0.4
2020 Vieira G, Cavalli J, Gonçalves ECD, Braga SFP, Ferreira RS, Santos ARS, Cola M, Raposo NRB, Capasso R, Dutra RC. Antidepressant-Like Effect of Terpineol in an Inflammatory Model of Depression: Involvement of the Cannabinoid System and D2 Dopamine Receptor. Biomolecules. 10. PMID 32443870 DOI: 10.3390/biom10050792  0.48
2020 Gonçalves ECD, Vieira G, Gonçalves TR, Simões RR, Brusco I, Oliveira SM, Calixto JB, Cola M, Santos ARS, Dutra RC. Bradykinin Receptors Play a Critical Role in the Chronic Post-ischaemia Pain Model. Cellular and Molecular Neurobiology. PMID 32222846 DOI: 10.1007/S10571-020-00832-3  0.76
2020 Gonçalves ECD, Assis PM, Junqueira LA, Cola M, Santos ARS, Raposo NRB, Dutra RC. Citral Inhibits the Inflammatory Response and Hyperalgesia in Mice: The Role of TLR4, TLR2/Dectin-1, and CB2 Cannabinoid Receptor/ATP-Sensitive K Channel Pathways. Journal of Natural Products. PMID 32150408 DOI: 10.1021/acs.jnatprod.9b01134  0.48
2019 Salgado ASI, Stramosk J, Ludtke DD, Kuci ACC, Salm DC, Ceci LA, Petronilho F, Florentino D, Danielski LG, Gassenferth A, Souza LR, Rezin GT, Santos ARS, Mazzardo-Martins L, Reed WR, et al. Manual Therapy Reduces Pain Behavior and Oxidative Stress in a Murine Model of Complex Regional Pain Syndrome Type I. Brain Sciences. 9. PMID 31405150 DOI: 10.3390/brainsci9080197  0.32
2019 Santos AR, Freitas P, Ferreira J, Oliveira A, Gonçalves M, Faria D, Bicho Augusto J, Simões J, Santos A, Gago M, Oliveira J, Antunes RM, Correia D, Lynce A, Brito J, et al. Risk stratification in normotensive acute pulmonary embolism patients: focus on the intermediate-high risk subgroup. European Heart Journal. Acute Cardiovascular Care. 2048872619846506. PMID 31017472 DOI: 10.1177/2048872619846506  0.6
2018 Freitas P, Santos AR, Ferreira AM, Oliveira A, Gonçalves M, Corte-Real A, Lameiras C, Maurício J, Ornelas É, Matos C, Faria D, Augusto J, Simões J, Ferreira I, Pedroso A, ... Santos AC, et al. Derivation and external validation of the SHIeLD score for predicting outcome in normotensive pulmonary embolism. International Journal of Cardiology. PMID 30638984 DOI: 10.1016/j.ijcard.2018.12.062  0.6
2018 da Rosa HS, Coelho IS, da Silva MD, Fernandes MS, Bertelli PR, Minetto L, Moura S, de Paula F, Santos AR, Mendez ASL, Folmer V. Sida tuberculata extract reduces the nociceptive response by chemical noxious stimuli in mice: Implications for mechanism of action, relation to chemical composition and molecular docking. Phytotherapy Research : Ptr. PMID 30375066 DOI: 10.1002/ptr.6220  0.32
2018 Cardoso GH, Petry DM, Probst JJ, de Souza LF, Ganguilhet G, Bobinski F, Santos ARS, Martins DF, Bonorino KC, Dafre AL, Hizume Kunzler DC. High-Intensity Exercise Prevents Disturbances in Lung Inflammatory Cytokines and Antioxidant Defenses Induced by Lipopolysaccharide. Inflammation. PMID 30030654 DOI: 10.1007/S10753-018-0849-9  0.32
2018 do Espírito Santo CC, Secco DD, Meireles A, de Freitas GR, Bobinski F, Cunha MP, Rodrigues ALS, Swarowsky A, Santos ARS, Ilha J. Locomotor Treadmill Training Promotes Soleus Trophism by Mammalian Target of Rapamycin Pathway in Paraplegic Rats. Neurochemical Research. PMID 29737479 DOI: 10.1007/S11064-018-2543-6  0.56
2017 Martins DF, Martins TC, Batisti AP, Dos Santos Leonel L, Bobinski F, Belmonte LAO, Mazzardo-Martins L, Cargnin-Ferreira E, Santos ARS. Long-Term Regular Eccentric Exercise Decreases Neuropathic Pain-like Behavior and Improves Motor Functional Recovery in an Axonotmesis Mouse Model: the Role of Insulin-like Growth Factor-1. Molecular Neurobiology. PMID 29250715 DOI: 10.1007/S12035-017-0829-3  0.32
2017 Neves LMS, Gonçalves ECD, Cavalli J, Vieira G, Laurindo LR, Simões RR, Coelho IS, Santos ARS, Marcolino AM, Cola M, Dutra RC. Photobiomodulation Therapy Improves Acute Inflammatory Response in Mice: the Role of Cannabinoid Receptors/ATP-Sensitive K(+) Channel/p38-MAPK Signalling Pathway. Molecular Neurobiology. PMID 28980210 DOI: 10.1007/s12035-017-0792-z  0.48
2017 Rodrigues Simões R, Dos Santos Coelho I, Célio Junqueira S, Regina Pigatto G, José Salvador M, Santos AR, de Faria FM. Oral treatment with essential oil of Hyptis spicigera Lam. (Lamiaceae) reduces acute pain and inflammation in mice: Potential interactions with transient receptor potential (TRP) ion channels. Journal of Ethnopharmacology. PMID 28213106 DOI: 10.1016/j.jep.2017.02.025  0.32
2016 Horinouchi CD, Mendes DA, Nolte S, Brito PS, Soley BD, Favero GM, Facundo VA, Santos AR, Cabrini DA, Otuki MF. Anti-proliferative and anti-inflammatory effects of 3β,6β,16β-Trihydroxylup-20(29)-ene on cutaneous inflammation. Journal of Ethnopharmacology. PMID 27880883 DOI: 10.1016/j.jep.2016.11.035  0.4
2016 Cunha MP, Pazini FL, Lieberknecht V, Budni J, Oliveira Á, Rosa JM, Mancini G, Mazzardo L, Colla AR, Leite MC, Santos AR, Martins DF, de Bem AF, Gonçalves CA, Farina M, et al. MPP(+)-Lesioned Mice: an Experimental Model of Motor, Emotional, Memory/Learning, and Striatal Neurochemical Dysfunctions. Molecular Neurobiology. PMID 27722926 DOI: 10.1007/s12035-016-0147-1  0.44
2016 Souza PS, Gonçalves ED, Pedroso GS, Farias HR, Junqueira SC, Marcon R, Tuon T, Cola M, Silveira PC, Santos AR, Calixto JB, Souza CT, de Pinho RA, Dutra RC. Physical Exercise Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Peripheral Immune Response and Blood-Brain Barrier Disruption. Molecular Neurobiology. PMID 27447807 DOI: 10.1007/S12035-016-0014-0  0.76
2016 Junqueira SC, Dos Santos Coelho I, Lieberknecht V, Cunha MP, Calixto JB, Rodrigues AL, Santos AR, Dutra RC. Inosine, an Endogenous Purine Nucleoside, Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis: a Role for A2A Adenosine Receptor. Molecular Neurobiology. PMID 27130268 DOI: 10.1007/S12035-016-9893-3  0.36
2016 Nucci-Martins C, Nascimento LF, Venzke D, Brethanha LC, Sako AV, Oliveira AS, Brighente IM, Micke GA, Pizzolatti MG, Santos AR. Antinociceptive effect of hydroalcoholic extract and isoflavone isolated from Polygala molluginifolia in mice: evidence for the involvement of opioid receptors and TRPV1 and TRPA1 channels. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 23: 429-40. PMID 27064002 DOI: 10.1016/j.phymed.2016.02.002  0.36
2016 Pigatto GR, Coelho IS, Aquino RS, Bauermann LF, Santos AR. Light-Emitting Diode Phototherapy Reduces Nocifensive Behavior Induced by Thermal and Chemical Noxious Stimuli in Mice: Evidence for the Involvement of Capsaicin-Sensitive Central Afferent Fibers. Molecular Neurobiology. PMID 27056078 DOI: 10.1007/s12035-016-9887-1  0.36
2016 Simões RR, Dos Santos Coelho I, do Espírito Santo CC, Morel AF, Zanchet EM, Santos AR. Oral treatment with methanolic extract of the root bark of Condalia buxifolia Reissek alleviates acute pain and inflammation in mice: Potential interactions with PGE2, TRPV1/ASIC and PKA Signaling Pathways. Journal of Ethnopharmacology. PMID 27013097 DOI: 10.1016/j.jep.2016.03.050  0.36
2016 Martins DF, Turnes BL, Cidral-Filho FJ, Bobinski F, Rosas RF, Danielski LG, Petronilho F, Santos AR. Light-emitting diode therapy reduces persistent inflammatory pain: Role of interleukin 10 and antioxidant enzymes. Neuroscience. PMID 27001179 DOI: 10.1016/J.Neuroscience.2016.03.035  0.32
2016 Dutra RC, Campos MM, Santos AR, Calixto JB. Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives. Pharmacological Research. PMID 26812486 DOI: 10.1016/J.Phrs.2016.01.021  0.48
2016 Lieberknecht V, Junqueira SC, Cunha MP, Barbosa TA, de Souza LF, Coelho IS, Santos AR, Rodrigues AL, Dafré AL, Dutra RC. Pramipexole, a Dopamine D2/D3 Receptor-Preferring Agonist, Prevents Experimental Autoimmune Encephalomyelitis Development in Mice. Molecular Neurobiology. PMID 26801190 DOI: 10.1007/s12035-016-9717-5  0.48
2015 Leivas CL, Nascimento LF, Barros WM, Santos AR, Iacomini M, Cordeiro LM. Substituted galacturonan from starfruit: Chemical structure and antinociceptive and anti-inflammatory effects. International Journal of Biological Macromolecules. PMID 26706843 DOI: 10.1016/j.ijbiomac.2015.12.034  0.48
2015 Lima FD, Stamm DN, Della Pace ID, Ribeiro LR, Rambo LM, Bresciani G, Ferreira J, Rossato MF, Silva MA, Pereira ME, Ineu RP, Santos AR, Bobinski F, Fighera MR, Royes LF. Ibuprofen intake increases exercise time to exhaustion: A possible role for preventing exercise-induced fatigue. Scandinavian Journal of Medicine & Science in Sports. PMID 26589249 DOI: 10.1111/Sms.12549  0.68
2015 da Silva MD, Cidral-Filho FJ, Winkelmann-Duarte EC, Cargnin-Ferreira E, Calixto JB, Dutra RC, Santos AR. Diacerein reduces joint damage, pain behavior and inhibits transient receptor potential vanilloid 1, matrix metalloproteinase and glial cells in rat spinal cord. International Journal of Rheumatic Diseases. PMID 26481104 DOI: 10.1111/1756-185X.12741  0.36
2015 Martins DF, Prado MR, Daruge E, Batisti AP, Emer AA, Mazzardo-Martins L, Santos AR, Piovezan AP. Caffeine prevents antihyperalgesic effect of gabapentin in an animal model of CRPS I: evidence for the involvement of spinal adenosine A1 receptor. Journal of the Peripheral Nervous System : Jpns. PMID 26456872 DOI: 10.1111/jns.12149  0.68
2015 Bobinski F, Alarcón Ferreira TA, Córdova MM, Dombrowski PA, da Cunha C, Santo CC, Poli A, Wanderley Pires RG, Martins-Silva C, Sluka KA, Soares Santos AR. Role of brainstem serotonin in analgesia produced by low-intensity exercise on neuropathic pain following sciatic nerve injury in mice. Pain. PMID 26447701 DOI: 10.1097/J.Pain.0000000000000372  0.36
2015 Simões RR, Coelho IS, Junqueira SC, Maldaner G, Morel AF, Venzke D, Ruani AP, Pizzolatti MG, Zanchet EM, Santos AR. Pharmacological evidence favouring the traditional use of the root bark of Condalia buxifolia Reissek in the relief of pain and inflammation in mice. Journal of Ethnopharmacology. PMID 26409180 DOI: 10.1016/j.jep.2015.09.028  0.4
2015 Nucci-Martins C, Martins DF, Nascimento LF, Venzke D, Oliveira AS, Frederico MJ, Silva FR, Brighente IM, Pizzolatti MG, Santos AR. Ameliorative potential of standardized fruit extract of Pterodon pubescens Benth on neuropathic pain in mice: Evidence for the mechanisms of action. Journal of Ethnopharmacology. PMID 26386380 DOI: 10.1016/j.jep.2015.09.005  0.4
2015 Martins DF, Emer AA, Paula Batisti A, Donatello N, Carlesso MG, Mazzardo-Martins L, Venzke D, Micke GA, Pizzolatti MG, Paula Piovezan A, Dos Santos AR. Inhalation of Cedrus atlantica essential oil Alleviates pain behavior through activation of descending pain modulation Pathways in a mouse model of postoperative pain. Journal of Ethnopharmacology. PMID 26344850 DOI: 10.1016/j.jep.2015.08.048  0.4
2015 Ávila LC, Bruggemann TR, Bobinski F, da Silva MD, Oliveira RC, Martins DF, Mazzardo-Martins L, Duarte MM, de Souza LF, Dafre A, Vieira Rde P, Santos AR, Bonorino KC, Hizume Kunzler Dde C. Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury. Plos One. 10: e0137273. PMID 26332044 DOI: 10.1371/Journal.Pone.0137273  0.32
2015 Nascimento FP, Macedo-Júnior SJ, Borges FR, Cremonese RP, da Silva MD, Luiz-Cerutti M, Martins DF, Rodrigues AL, Santos AR. Thalidomide reduces mechanical hyperalgesia and depressive-like behavior induced by peripheral nerve crush in mice. Neuroscience. 303: 51-8. PMID 26126925 DOI: 10.1016/j.neuroscience.2015.06.044  0.44
2015 Brüggemann TR, Ávila LC, Fortkamp B, Greiffo FR, Bobinski F, Mazzardo-Martins L, Martins DF, Duarte MM, Dafre A, Santos AR, Silva MD, Souza LF, Vieira RP, Hizume-Kunzler DC. Effects of Swimming on the Inflammatory and Redox Response in a Model of Allergic Asthma. International Journal of Sports Medicine. PMID 25958938 DOI: 10.1055/S-0035-1549904  0.4
2015 Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira AB, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, de Souza Melo CP, Silveira AB, Leal PC, Frederico MJ, do Nascimento LF, ... Santos AR, et al. N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia. European Journal of Medicinal Chemistry. 96: 504-18. PMID 25951294 DOI: 10.1016/J.Ejmech.2015.02.041  0.36
2015 Castro AJ, Cazarolli LH, de Carvalho FK, da Luz G, Altenhofen D, dos Santos AR, Pizzolatti MG, Silva FR. Acute effect of 3β-hidroxihop-22(29)ene on insulin secretion is mediated by GLP-1, potassium and calcium channels for the glucose homeostasis. The Journal of Steroid Biochemistry and Molecular Biology. 150: 112-22. PMID 25843210 DOI: 10.1016/j.jsbmb.2015.03.011  0.4
2015 Brüggemann TR, Ávila LC, Fortkamp B, Greiffo FR, Bobinski F, Mazzardo-Martins L, Martins DF, Duarte MM, Dafre A, Santos AR, Silva MD, Souza LF, Vieira RP, Hizume-Kunzler DC. Effects of Swimming on the Inflammatory and Redox Response in a Model of Allergic Asthma. International Journal of Sports Medicine. 36: 579-84. PMID 25837246 DOI: 10.1055/s-0034-1395588  0.32
2015 Martins DF, Brito RN, Stramosk J, Batisti AP, Madeira F, Turnes BL, Mazzardo-Martins L, Santos AR, Piovezan AP. Peripheral neurobiologic mechanisms of antiallodynic effect of warm water immersion therapy on persistent inflammatory pain. Journal of Neuroscience Research. 93: 157-66. PMID 25079058 DOI: 10.1002/jnr.23461  0.32
2015 Nascimento FP, Macedo-Júnior SJ, Pamplona FA, Luiz-Cerutti M, Córdova MM, Constantino L, Tasca CI, Dutra RC, Calixto JB, Reid A, Sawynok J, Santos AR. Adenosine A1 receptor-dependent antinociception induced by inosine in mice: pharmacological, genetic and biochemical aspects. Molecular Neurobiology. 51: 1368-78. PMID 25064055 DOI: 10.1007/S12035-014-8815-5  0.36
2015 da Silva MD, Bobinski F, Sato KL, Kolker SJ, Sluka KA, Santos AR. IL-10 cytokine released from M2 macrophages is crucial for analgesic and anti-inflammatory effects of acupuncture in a model of inflammatory muscle pain. Molecular Neurobiology. 51: 19-31. PMID 24961568 DOI: 10.1007/S12035-014-8790-X  0.36
2014 Basting RT, Nishijima CM, Lopes JA, Santos RC, Lucena Périco L, Laufer S, Bauer S, Costa MF, Santos LC, Rocha LR, Vilegas W, Santos AR, Dos Santos C, Hiruma-Lima CA. Antinociceptive, anti-inflammatory and gastroprotective effects of a hydroalcoholic extract from the leaves of Eugenia punicifolia (Kunth) DC. in rodents. Journal of Ethnopharmacology. 157: 257-67. PMID 25311275 DOI: 10.1016/J.Jep.2014.09.041  0.36
2014 Nishijima CM, Ganev EG, Mazzardo-Martins L, Martins DF, Rocha LR, Santos AR, Hiruma-Lima CA. Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain. European Journal of Pharmacology. 736: 16-25. PMID 24792822 DOI: 10.1016/j.ejphar.2014.04.029  0.32
2014 Kalegari M, Cerutti ML, Macedo-Júnior SJ, Bobinski F, Miguel MD, Eparvier V, Santos AR, Stien D, Miguel OG. Chemical composition and antinociceptive effect of aqueous extract from Rourea induta Planch. leaves in acute and chronic pain models. Journal of Ethnopharmacology. 153: 801-9. PMID 24680990 DOI: 10.1016/J.Jep.2014.03.045  0.48
2014 Trevisan G, Rossato MF, Hoffmeister C, Müller LG, Pase C, Córdova MM, Rosa F, Tonello R, Hausen BS, Boligon AA, Moresco RN, Athayde ML, Burguer ME, Santos AR, Ferreira J. Antinociceptive and antiedematogenic effect of pecan (Carya illinoensis) nut shell extract in mice: a possible beneficial use for a by-product of the nut industry. Journal of Basic and Clinical Physiology and Pharmacology. 1-10. PMID 24468619 DOI: 10.1515/jbcpp-2013-0137  0.6
2014 Assis LC, Hort MA, de Souza GV, Martini AC, Forner S, Martins DF, Silva JC, Horst H, dos Santos AR, Pizzolatti MG, Rae GA, Koepp J, de Bem AF, do Valle RM. Neuroprotective effect of the proanthocyanidin-rich fraction in experimental model of spinal cord injury. The Journal of Pharmacy and Pharmacology. 66: 694-704. PMID 24438047 DOI: 10.1111/jphp.12177  0.4
2014 Ferreira AP, Rodrigues FS, Della-Pace ID, Mota BC, Oliveira SM, de Campos Velho Gewehr C, Bobinski F, de Oliveira CV, Brum JS, Oliveira MS, Furian AF, de Barros CS, dos Santos AR, Ferreira J, Fighera MR, et al. HOE-140, an antagonist of B2 receptor, protects against memory deficits and brain damage induced by moderate lateral fluid percussion injury in mice. Psychopharmacology. 231: 1935-48. PMID 24202114 DOI: 10.1007/S00213-013-3336-X  0.6
2014 Borges FR, Silva MD, Córdova MM, Schambach TR, Pizzolatti MG, Santos AR. Anti-inflammatory action of hydroalcoholic extract, dichloromethane fraction and steroid α-spinasterol from Polygala sabulosa in LPS-induced peritonitis in mice. Journal of Ethnopharmacology. 151: 144-50. PMID 24161429 DOI: 10.1016/j.jep.2013.10.009  0.4
2014 Cidral-Filho FJ, Mazzardo-Martins L, Martins DF, Santos AR. Light-emitting diode therapy induces analgesia in a mouse model of postoperative pain through activation of peripheral opioid receptors and the L-arginine/nitric oxide pathway. Lasers in Medical Science. 29: 695-702. PMID 23832179 DOI: 10.1007/s10103-013-1385-3  0.32
2013 Moré AO, Cidral-Filho FJ, Mazzardo-Martins L, Martins DF, Nascimento FP, Li SM, Santos AR. Caffeine at Moderate Doses Can Inhibit Acupuncture-Induced Analgesia in a Mouse Model of Postoperative Pain. Journal of Caffeine Research. 3: 143-148. PMID 24761281 DOI: 10.1089/jcr.2013.0014  0.32
2013 Machado JA, Ghizoni MF, Bertelli J, Teske GC, Teske GC, Martins DF, Mazzardo-Martins L, Cargnin-Ferreira E, Santos AR, Piovezan AP. Stretch-induced nerve injury: a proposed technique for the study of nerve regeneration and evaluation of the influence of gabapentin on this model. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas / Sociedade Brasileira De Biofisica ... [Et Al.]. 46: 929-935. PMID 24270909 DOI: 10.1590/1414-431X20132863  0.32
2013 Martins DF, Mazzardo-Martins L, Cidral-Filho FJ, Gadotti VM, Santos AR. Peripheral and spinal activation of cannabinoid receptors by joint mobilization alleviates postoperative pain in mice. Neuroscience. 255: 110-21. PMID 24120553 DOI: 10.1016/j.neuroscience.2013.09.055  0.56
2013 Ferreira AP, Rodrigues FS, Della-Pace ID, Mota BC, Oliveira SM, Velho Gewehr Cde C, Bobinski F, de Oliveira CV, Brum JS, Oliveira MS, Furian AF, de Barros CS, Ferreira J, Santos AR, Fighera MR, et al. The effect of NADPH-oxidase inhibitor apocynin on cognitive impairment induced by moderate lateral fluid percussion injury: role of inflammatory and oxidative brain damage. Neurochemistry International. 63: 583-93. PMID 24076474 DOI: 10.1016/J.Neuint.2013.09.012  0.68
2013 Walker CI, Trevisan G, Rossato MF, Silva CR, Pinheiro FV, Franciscato C, Tatsch E, Moretto MB, Silva MD, Manfron MP, Noal Moresco R, Santos AR, Pereira ME, Ferreira J. Antinociceptive effect of Mirabilis jalapa on acute and chronic pain models in mice. Journal of Ethnopharmacology. 149: 685-93. PMID 23906783 DOI: 10.1016/j.jep.2013.07.027  0.6
2013 Sassaki GL, Rattmann YD, Santana-Filho AP, Riter DS, Iagher F, Trindade ES, da Silva MD, Santos AR, de Souza LM, Iacomini M, Gorin PA. Galactofuranosyl glycosides: immunomodulatory effects on macrophages and in vivo enhancement of lethality on sepsis. Chemico-Biological Interactions. 205: 29-37. PMID 23756126 DOI: 10.1016/j.cbi.2013.05.014  0.32
2013 Prudente AS, Loddi AM, Duarte MR, Santos AR, Pochapski MT, Pizzolatti MG, Hayashi SS, Campos FR, Pontarolo R, Santos FA, Cabrini DA, Otuki MF. Pre-clinical anti-inflammatory aspects of a cuisine and medicinal millennial herb: Malva sylvestris L. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 58: 324-31. PMID 23684757 DOI: 10.1016/j.fct.2013.04.042  0.4
2013 Kaster MP, Budni J, Gazal M, Cunha MP, Santos AR, Rodrigues AL. The antidepressant-like effect of inosine in the FST is associated with both adenosine A1 and A 2A receptors. Purinergic Signalling. 9: 481-6. PMID 23613131 DOI: 10.1007/S11302-013-9361-8  0.68
2013 Coelho V, Mazzardo-Martins L, Martins DF, Santos AR, da Silva Brum LF, Picada JN, Pereira P. Neurobehavioral and genotoxic evaluation of (-)-linalool in mice. Journal of Natural Medicines. 67: 876-80. PMID 23436179 DOI: 10.1007/s11418-013-0751-6  0.32
2013 Córdova MM, Martins DF, Silva MD, Baggio CH, Carbonero ER, Ruthes AC, Iacomini M, Santos AR. Polysaccharide glucomannan isolated from Heterodermia obscurata attenuates acute and chronic pain in mice. Carbohydrate Polymers. 92: 2058-64. PMID 23399258 DOI: 10.1016/j.carbpol.2012.11.041  0.4
2013 Cidral-Filho FJ, Martins DF, Moré AO, Mazzardo-Martins L, Silva MD, Cargnin-Ferreira E, Santos AR. Light-emitting diode therapy induces analgesia and decreases spinal cord and sciatic nerve tumour necrosis factor-α levels after sciatic nerve crush in mice. European Journal of Pain (London, England). 17: 1193-204. PMID 23339021 DOI: 10.1002/j.1532-2149.2012.00280.x  0.4
2013 Erthal V, da Silva MD, Cidral-Filho FJ, Santos AR, Nohama P. ST36 laser acupuncture reduces pain-related behavior in rats: involvement of the opioidergic and serotonergic systems. Lasers in Medical Science. 28: 1345-51. PMID 23291880 DOI: 10.1007/s10103-012-1260-7  0.32
2013 Martins DF, Mazzardo-Martins L, Soldi F, Stramosk J, Piovezan AP, Santos AR. High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system. Neuroscience. 234: 69-76. PMID 23291454 DOI: 10.1016/j.neuroscience.2012.12.042  0.32
2013 Della-Pace ID, Rambo LM, Ribeiro LR, Saraiva AL, de Oliveira SM, Silva CR, Villarinho JG, Rossato MF, Ferreira J, de Carvalho LM, de Oliveira Lima F, Furian AF, Oliveria MS, Santos AR, Facundo VA, et al. Triterpene 3β, 6β, 16β trihidroxilup-20(29)-ene protects against excitability and oxidative damage induced by pentylenetetrazol: the role of Na(+),K(+)-ATPase activity. Neuropharmacology. 67: 455-64. PMID 23219656 DOI: 10.1016/j.neuropharm.2012.10.022  0.68
2013 Cunha MP, Oliveira Á, Pazini FL, Machado DG, Bettio LE, Budni J, Aguiar AS, Martins DF, Santos AR, Rodrigues AL. The antidepressant-like effect of physical activity on a voluntary running wheel. Medicine and Science in Sports and Exercise. 45: 851-9. PMID 23190594 DOI: 10.1249/MSS.0b013e31827b23e6  0.36
2013 Horinouchi CD, Mendes DA, Soley Bda S, Pietrovski EF, Facundo VA, Santos AR, Cabrini DA, Otuki MF. Combretum leprosum Mart. (Combretaceae): potential as an antiproliferative and anti-inflammatory agent. Journal of Ethnopharmacology. 145: 311-9. PMID 23159472 DOI: 10.1016/j.jep.2012.10.064  0.4
2013 Martins DF, Mazzardo-Martins L, Cidral-Filho FJ, Stramosk J, Santos AR. Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors. Physical Therapy. 93: 401-12. PMID 23086409 DOI: 10.2522/ptj.20120226  0.32
2013 Macedo-Junior SJ, Nascimento FP, Luiz-Cerutti M, Santos AR. Role of pertussis toxin-sensitive G-protein, K+ channels, and voltage-gated Ca2+ channels in the antinociceptive effect of inosine. Purinergic Signalling. 9: 51-8. PMID 22806273 DOI: 10.1007/s11302-012-9327-2  0.36
2013 Dal Bó W, Luiz AP, Martins DF, Mazzardo-Martins L, Santos AR. Eugenol reduces acute pain in mice by modulating the glutamatergic and tumor necrosis factor alpha (TNF-α) pathways. Fundamental & Clinical Pharmacology. 27: 517-25. PMID 22775297 DOI: 10.1111/j.1472-8206.2012.01052.x  0.4
2012 Mazzardo-Martins L, Martins DF, Stramosk J, Cidral-Filho FJ, Santos AR. Glycogen synthase kinase 3-specific inhibitor AR-A014418 decreases neuropathic pain in mice: evidence for the mechanisms of action. Neuroscience. 226: 411-20. PMID 23000630 DOI: 10.1016/j.neuroscience.2012.09.020  0.32
2012 Matheus FC, Aguiar AS, Castro AA, Villarinho JG, Ferreira J, Figueiredo CP, Walz R, Santos AR, Tasca CI, Prediger RD. Neuroprotective effects of agmatine in mice infused with a single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Behavioural Brain Research. 235: 263-72. PMID 22921927 DOI: 10.1016/J.Bbr.2012.08.017  0.68
2012 Montrucchio DP, Miguel OG, Zanin SM, da Silva GA, Cardozo AM, Santos AR. Antinociceptive effects of a chloroform extract and the alkaloid dicentrine isolated from fruits of Ocotea puberula. Planta Medica. 78: 1543-8. PMID 22815198 DOI: 10.1055/s-0032-1315026  0.48
2012 Kaster MP, Machado DG, Santos AR, Rodrigues AL. Involvement of NMDA receptors in the antidepressant-like action of adenosine. Pharmacological Reports : Pr. 64: 706-13. PMID 22814023 DOI: 10.1016/S1734-1140(12)70865-4  0.68
2012 Martins DF, Bobinski F, Mazzardo-Martins L, Cidral-Filho FJ, Nascimento FP, Gadotti VM, Santos AR. Ankle joint mobilization decreases hypersensitivity by activation of peripheral opioid receptors in a mouse model of postoperative pain. Pain Medicine (Malden, Mass.). 13: 1049-58. PMID 22776137 DOI: 10.1111/J.1526-4637.2012.01438.X  0.56
2012 Gadotti VM, Martins DF, Pinto HF, Oliveira G, Kaster MP, Quintão NL, Santos AR. Diacerein decreases visceral pain through inhibition of glutamatergic neurotransmission and cytokine signaling in mice. Pharmacology, Biochemistry, and Behavior. 102: 549-54. PMID 22750064 DOI: 10.1016/J.Pbb.2012.06.018  0.68
2012 Nucci C, Mazzardo-Martins L, Stramosk J, Brethanha LC, Pizzolatti MG, Santos AR, Martins DF. Oleaginous extract from the fruits Pterodon pubescens Benth induces antinociception in animal models of acute and chronic pain. Journal of Ethnopharmacology. 143: 170-8. PMID 22728247 DOI: 10.1016/j.jep.2012.06.020  0.4
2012 Rattmann YD, Anselm E, Kim JH, Dal-Ros S, Auger C, Miguel OG, Santos AR, Chataigneau T, Schini-Kerth VB. Natural product extract of Dicksonia sellowiana induces endothelium-dependent relaxations by a redox-sensitive Src- and Akt-dependent activation of eNOS in porcine coronary arteries. Journal of Vascular Research. 49: 284-98. PMID 22538863 DOI: 10.1159/000336647  0.68
2012 da Rocha Lapa F, da Silva MD, de Almeida Cabrini D, Santos AR. Anti-inflammatory effects of purine nucleosides, adenosine and inosine, in a mouse model of pleurisy: evidence for the role of adenosine A2 receptors. Purinergic Signalling. 8: 693-704. PMID 22456813 DOI: 10.1007/s11302-012-9299-2  0.32
2012 Saragusti AC, Bustos PS, Pierosan L, Cabrera JL, Chiabrando GA, Santos AR, Ortega MG. Involvement of the L-arginine-nitric oxide pathway in the antinociception caused by fruits of Prosopis strombulifera (Lam.) Benth. Journal of Ethnopharmacology. 140: 117-22. PMID 22230471 DOI: 10.1016/j.jep.2011.12.044  0.68
2012 Rodrigues MR, Kanazawa LK, das Neves TL, da Silva CF, Horst H, Pizzolatti MG, Santos AR, Baggio CH, Werner MF. Antinociceptive and anti-inflammatory potential of extract and isolated compounds from the leaves of Salvia officinalis in mice. Journal of Ethnopharmacology. 139: 519-26. PMID 22154965 DOI: 10.1016/j.jep.2011.11.042  0.4
2012 Kaster MP, Gadotti VM, Calixto JB, Santos AR, Rodrigues AL. Depressive-like behavior induced by tumor necrosis factor-α in mice. Neuropharmacology. 62: 419-26. PMID 21867719 DOI: 10.1016/J.Neuropharm.2011.08.018  0.68
2012 Mota BC, Pereira L, Souza MA, Silva LF, Magni DV, Ferreira AP, Oliveira MS, Furian AF, Mazzardo-Martins L, Silva MD, Santos AR, Ferreira J, Fighera MR, Royes LF. Exercise pre-conditioning reduces brain inflammation and protects against toxicity induced by traumatic brain injury: behavioral and neurochemical approach. Neurotoxicity Research. 21: 175-84. PMID 21735317 DOI: 10.1007/S12640-011-9257-8  0.6
2011 Bettio LE, Machado DG, Cunha MP, Capra JC, Missau FC, Santos AR, Pizzolatti MG, Rodrigues AL. Antidepressant-like effect of extract from Polygala paniculata: involvement of the monoaminergic systems. Pharmaceutical Biology. 49: 1277-85. PMID 22077163 DOI: 10.3109/13880209.2011.621958  0.68
2011 Martins DF, Mazzardo-Martins L, Gadotti VM, Nascimento FP, Lima DA, Speckhann B, Favretto GA, Bobinski F, Cargnin-Ferreira E, Bressan E, Dutra RC, Calixto JB, Santos AR. Ankle joint mobilization reduces axonotmesis-induced neuropathic pain and glial activation in the spinal cord and enhances nerve regeneration in rats. Pain. 152: 2653-61. PMID 21906878 DOI: 10.1016/J.Pain.2011.08.014  0.68
2011 Bobinski F, Martins DF, Bratti T, Mazzardo-Martins L, Winkelmann-Duarte EC, Guglielmo LG, Santos AR. Neuroprotective and neuroregenerative effects of low-intensity aerobic exercise on sciatic nerve crush injury in mice. Neuroscience. 194: 337-48. PMID 21864654 DOI: 10.1016/J.Neuroscience.2011.07.075  0.32
2011 Cidral-Filho FJ, da Silva MD, Moré AO, Córdova MM, Werner MF, Santos AR. Manual acupuncture inhibits mechanical hypersensitivity induced by spinal nerve ligation in rats. Neuroscience. 193: 370-6. PMID 21835228 DOI: 10.1016/j.neuroscience.2011.07.076  0.32
2011 da Silva MD, Guginski G, Werner MF, Baggio CH, Marcon R, Santos AR. Involvement of Interleukin-10 in the Anti-Inflammatory Effect of Sanyinjiao (SP6) Acupuncture in a Mouse Model of Peritonitis. Evidence-Based Complementary and Alternative Medicine : Ecam. 2011: 217946. PMID 21799673 DOI: 10.1093/ecam/neq036  0.32
2011 Pereira M, Siba IP, Chioca LR, Correia D, Vital MA, Pizzolatti MG, Santos AR, Andreatini R. Myricitrin, a nitric oxide and protein kinase C inhibitor, exerts antipsychotic-like effects in animal models. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 1636-44. PMID 21689712 DOI: 10.1016/j.pnpbp.2011.06.002  0.4
2011 Lapa Fda R, Soares KC, Rattmann YD, Crestani S, Missau FC, Pizzolatti MG, Marques MC, Rieck L, Santos AR. Vasorelaxant and hypotensive effects of the extract and the isolated flavonoid rutin obtained from Polygala paniculata L. The Journal of Pharmacy and Pharmacology. 63: 875-81. PMID 21585387 DOI: 10.1111/j.2042-7158.2010.01240.x  0.4
2011 Coelho VR, Gianesini J, Von Borowski R, Mazzardo-Martins L, Martins DF, Picada JN, Santos AR, Brum LF, Pereira P. (-)-Linalool, a naturally occurring monoterpene compound, impairs memory acquisition in the object recognition task, inhibitory avoidance test and habituation to a novel environment in rats. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 18: 896-901. PMID 21420842 DOI: 10.1016/j.phymed.2011.02.010  0.32
2011 Figueredo SM, do Nascimento FP, Freitas CS, Baggio CH, Soldi C, Pizzolatti MG, de Ibarrola Mdel C, de Arrua RL, Santos AR. Antinociceptive and gastroprotective actions of ethanolic extract from Pluchea sagittalis (Lam.) Cabrera. Journal of Ethnopharmacology. 135: 603-9. PMID 21392568 DOI: 10.1016/j.jep.2011.03.006  0.4
2011 Córdova MM, Werner MF, Silva MD, Ruani AP, Pizzolatti MG, Santos AR. Further antinociceptive effects of myricitrin in chemical models of overt nociception in mice. Neuroscience Letters. 495: 173-7. PMID 21315136 DOI: 10.1016/j.neulet.2011.02.007  0.4
2011 Magni DV, Souza MA, Oliveira AP, Furian AF, Oliveira MS, Ferreira J, Santos AR, Mello CF, Royes LF, Fighera MR. Lipopolysaccharide enhances glutaric acid-induced seizure susceptibility in rat pups: behavioral and electroencephalographic approach. Epilepsy Research. 93: 138-48. PMID 21183317 DOI: 10.1016/J.Eplepsyres.2010.11.007  0.6
2011 Longhi-Balbinot DT, Martins DF, Lanznaster D, Silva MD, Facundo VA, Santos AR. Further analyses of mechanisms underlying the antinociceptive effect of the triterpene 3β, 6β, 16β-trihydroxylup-20(29)-ene in mice. European Journal of Pharmacology. 653: 32-40. PMID 21156170 DOI: 10.1016/j.ejphar.2010.11.028  0.4
2011 Rattmann YD, Mendéz-Sánchez SC, Furian AF, Paludo KS, de Souza LM, Dartora N, Oliveira MS, Costa EM, Miguel OG, Sassaki GL, Iacomini M, Mello CF, Franco CR, da Silva-Santos JE, Cadena SM, ... ... Santos AR, et al. Standardized extract of Dicksonia sellowiana Presl. Hook (Dicksoniaceae) decreases oxidative damage in cultured endothelial cells and in rats. Journal of Ethnopharmacology. 133: 999-1007. PMID 21094243 DOI: 10.1016/J.Jep.2010.11.030  0.48
2011 Martins DF, Rosa AO, Gadotti VM, Mazzardo-Martins L, Nascimento FP, Egea J, López MG, Santos AR. The antinociceptive effects of AR-A014418, a selective inhibitor of glycogen synthase kinase-3 beta, in mice. The Journal of Pain : Official Journal of the American Pain Society. 12: 315-22. PMID 20705523 DOI: 10.1016/J.Jpain.2010.06.007  0.68
2010 Franco JL, Posser T, Missau F, Pizzolatti MG, Dos Santos AR, Souza DO, Aschner M, Rocha JB, Dafre AL, Farina M. Structure-activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction. Environmental Toxicology and Pharmacology. 30: 272-278. PMID 21127717 DOI: 10.1016/J.Etap.2010.07.003  0.4
2010 Capra JC, Cunha MP, Machado DG, Zomkowski AD, Mendes BG, Santos AR, Pizzolatti MG, Rodrigues AL. Antidepressant-like effect of scopoletin, a coumarin isolated from Polygala sabulosa (Polygalaceae) in mice: evidence for the involvement of monoaminergic systems. European Journal of Pharmacology. 643: 232-8. PMID 20599906 DOI: 10.1016/j.ejphar.2010.06.043  0.68
2010 Mazzardo-Martins L, Martins DF, Marcon R, Dos Santos UD, Speckhann B, Gadotti VM, Sigwalt AR, Guglielmo LG, Santos AR. High-intensity extended swimming exercise reduces pain-related behavior in mice: involvement of endogenous opioids and the serotonergic system. The Journal of Pain : Official Journal of the American Pain Society. 11: 1384-93. PMID 20488763 DOI: 10.1016/j.jpain.2010.03.015  0.56
2010 Nascimento FP, Figueredo SM, Marcon R, Martins DF, Macedo SJ, Lima DA, Almeida RC, Ostroski RM, Rodrigues AL, Santos AR. Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways. The Journal of Pharmacology and Experimental Therapeutics. 334: 590-8. PMID 20472668 DOI: 10.1124/jpet.110.166058  0.44
2010 Batista PA, Werner MF, Oliveira EC, Burgos L, Pereira P, Brum LF, Story GM, Santos AR. The antinociceptive effect of (-)-linalool in models of chronic inflammatory and neuropathic hypersensitivity in mice. The Journal of Pain : Official Journal of the American Pain Society. 11: 1222-9. PMID 20452289 DOI: 10.1016/j.jpain.2010.02.022  0.68
2010 Binfaré RW, Mantovani M, Budni J, Santos AR, Rodrigues AL. Involvement of dopamine receptors in the antidepressant-like effect of melatonin in the tail suspension test. European Journal of Pharmacology. 638: 78-83. PMID 20406627 DOI: 10.1016/j.ejphar.2010.04.011  0.48
2010 Meotti FC, Coelho Idos S, Santos AR. The nociception induced by glutamate in mice is potentiated by protons released into the solution. The Journal of Pain : Official Journal of the American Pain Society. 11: 570-8. PMID 20338819 DOI: 10.1016/j.jpain.2009.09.012  0.4
2010 Pasin JS, Ferreira AP, Saraiva AL, Ratzlaff V, Andrighetto R, Tomazetti J, Avila DS, Alves SH, Rubin MA, Ferreira J, Santos AR, Mello CF. Diacerein decreases TNF-alpha and IL-1beta levels in peritoneal fluid and prevents Baker's yeast-induced fever in young rats. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 59: 189-96. PMID 19730987 DOI: 10.1007/s00011-009-0085-8  0.6
2009 Longhi-Balbinot DT, Pietrovski EF, Gadotti VM, Martins DF, Facundo VA, Santos AR. Spinal antinociception evoked by the triterpene 3beta, 6beta, 16beta-trihydroxylup-20(29)-ene in mice: evidence for the involvement of the glutamatergic system via NMDA and metabotropic glutamate receptors. European Journal of Pharmacology. 623: 30-6. PMID 19765585 DOI: 10.1016/j.ejphar.2009.09.004  0.56
2009 Marcon R, Luiz AP, Werner MF, Freitas CS, Baggio CH, Nascimento FP, Soldi C, Pizzolatti MG, Santos AR. Evidence of TRPV1 receptor and PKC signaling pathway in the antinociceptive effect of amyrin octanoate. Brain Research. 1295: 76-88. PMID 19646975 DOI: 10.1016/j.brainres.2009.07.073  0.4
2009 Werner JA, Oliveira SM, Martins DF, Mazzardo L, Dias Jde F, Lordello AL, Miguel OG, Royes LF, Ferreira J, Santos AR. Evidence for a role of 5-HT(1A) receptor on antinociceptive action from Geissospermum vellosii. Journal of Ethnopharmacology. 125: 163-9. PMID 19497357 DOI: 10.1016/j.jep.2009.05.026  0.6
2009 Binfaré RW, Rosa AO, Lobato KR, Santos AR, Rodrigues AL. Ascorbic acid administration produces an antidepressant-like effect: evidence for the involvement of monoaminergic neurotransmission. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 33: 530-40. PMID 19439241 DOI: 10.1016/j.pnpbp.2009.02.003  0.44
2009 Freitas CS, Baggio CH, Twardowschy A, dos Santos AC, Mayer B, Luiz AP, dos Santos CA, Marques MC, dos Santos AR. Involvement of glutamate and cytokine pathways on antinociceptive effect of Pfaffia glomerata in mice. Journal of Ethnopharmacology. 122: 468-72. PMID 19429314 DOI: 10.1016/j.jep.2009.01.033  0.4
2009 Guginski G, Luiz AP, Silva MD, Massaro M, Martins DF, Chaves J, Mattos RW, Silveira D, Ferreira VM, Calixto JB, Santos AR. Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice. Pharmacology, Biochemistry, and Behavior. 93: 10-6. PMID 19358864 DOI: 10.1016/J.Pbb.2009.03.014  0.68
2009 Lapa Fda R, Gadotti VM, Missau FC, Pizzolatti MG, Marques MC, Dafré AL, Farina M, Rodrigues AL, Santos AR. Antinociceptive properties of the hydroalcoholic extract and the flavonoid rutin obtained from Polygala paniculata L. in mice. Basic & Clinical Pharmacology & Toxicology. 104: 306-15. PMID 19281602 DOI: 10.1111/j.1742-7843.2008.00365.x  0.56
2009 Freitas CS, Baggio CH, Dos Santos AC, Mayer B, Twardowschy A, Luiz AP, Marcon R, Soldi C, Pizzolatti MG, Dos Santos EP, Marques MC, Santos AR. Antinociceptive properties of the hydroalcoholic extract, fractions and compounds obtained from the aerial parts of Baccharis illinita DC in mice. Basic & Clinical Pharmacology & Toxicology. 104: 285-92. PMID 19281601 DOI: 10.1111/j.1742-7843.2008.00367.x  0.4
2009 Brocardo PS, Budni J, Lobato KR, Santos AR, Rodrigues AL. Evidence for the involvement of the opioid system in the antidepressant-like effect of folic acid in the mouse forced swimming test. Behavioural Brain Research. 200: 122-7. PMID 19162083 DOI: 10.1016/j.bbr.2009.01.004  0.44
2009 Martins Rde P, Braga Hde C, da Silva AP, Dalmarco JB, de Bem AF, dos Santos AR, Dafre AL, Pizzolatti MG, Latini A, Aschner M, Farina M. Synergistic neurotoxicity induced by methylmercury and quercetin in mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 47: 645-9. PMID 19141311 DOI: 10.1016/J.Fct.2008.12.020  0.4
2009 Ribeiro LR, Fighera MR, Oliveira MS, Furian AF, Rambo LM, Ferreira AP, Saraiva AL, Souza MA, Lima FD, Magni DV, Dezengrini R, Flores EF, Butterfield DA, Ferreira J, dos Santos AR, et al. Methylmalonate-induced seizures are attenuated in inducible nitric oxide synthase knockout mice. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 27: 157-63. PMID 19073247 DOI: 10.1016/J.Ijdevneu.2008.11.005  0.68
2009 Cardoso CC, Lobato KR, Binfaré RW, Ferreira PK, Rosa AO, Santos AR, Rodrigues AL. Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 33: 235-42. PMID 19059299 DOI: 10.1016/j.pnpbp.2008.11.007  0.44
2009 Meotti FC, Coelho IS, Franco JL, Dafre AL, Rocha JB, Santos AR. Redox modulation at the peripheral site alters nociceptive transmission in vivo. Clinical and Experimental Pharmacology & Physiology. 36: 272-7. PMID 18986332 DOI: 10.1111/j.1440-1681.2008.05056.x  0.4
2009 Rattmann YD, Crestani S, Lapa FR, Miguel OG, Marques MC, da Silva-Santos JE, Santos AR. Activation of muscarinic receptors by a hydroalcoholic extract of Dicksonia sellowiana Presl. HooK (Dicksoniaceae) induces vascular relaxation and hypotension in rats. Vascular Pharmacology. 50: 27-33. PMID 18805508 DOI: 10.1016/j.vph.2008.08.005  0.48
2008 Smiderle FR, Olsen LM, Carbonero ER, Marcon R, Baggio CH, Freitas CS, Santos AR, Torri G, Gorin PA, Iacomini M. A 3-O-methylated mannogalactan from Pleurotus pulmonarius: structure and antinociceptive effect. Phytochemistry. 69: 2731-6. PMID 18834999 DOI: 10.1016/j.phytochem.2008.08.006  0.68
2008 Smiderle FR, Olsen LM, Carbonero ER, Baggio CH, Freitas CS, Marcon R, Santos AR, Gorin PA, Iacomini M. Anti-inflammatory and analgesic properties in a rodent model of a (1-->3),(1-->6)-linked beta-glucan isolated from Pleurotus pulmonarius. European Journal of Pharmacology. 597: 86-91. PMID 18789924 DOI: 10.1016/j.ejphar.2008.08.028  0.68
2008 Freitas CS, Baggio CH, Finau J, Anginoni M, Pizzolatti MG, Santos AR, Marques MC. Inhibition of H+/K+ ATPase in the gastroprotective effect of Baccharis illinita DC. The Journal of Pharmacy and Pharmacology. 60: 1105-10. PMID 18644203 DOI: 10.1211/jpp.60.8.0017  0.4
2008 Ribas CM, Meotti FC, Nascimento FP, Jacques AV, Dafre AL, Rodrigues AL, Farina M, Soldi C, Mendes BG, Pizzolatti MG, Santos AR. Antinociceptive effect of the Polygala sabulosa hydroalcoholic extract in mice: evidence for the involvement of glutamatergic receptors and cytokine pathways. Basic & Clinical Pharmacology & Toxicology. 103: 43-7. PMID 18598298 DOI: 10.1111/j.1742-7843.2008.00245.x  0.44
2008 Machado DG, Bettio LE, Cunha MP, Santos AR, Pizzolatti MG, Brighente IM, Rodrigues AL. Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: evidence for the involvement of the serotonergic and noradrenergic systems. European Journal of Pharmacology. 587: 163-8. PMID 18457827 DOI: 10.1016/j.ejphar.2008.03.021  0.68
2008 Trevisan R, Uliano-Silva M, Pandolfo P, Franco JL, Brocardo PS, Santos AR, Farina M, Rodrigues AL, Takahashi RN, Dafre AL. Antioxidant and acetylcholinesterase response to repeated malathion exposure in rat cerebral cortex and hippocampus. Basic & Clinical Pharmacology & Toxicology. 102: 365-9. PMID 18341513 DOI: 10.1111/J.1742-7843.2007.00182.X  0.68
2008 Lobato KR, Binfaré RW, Budni J, Rosa AO, Santos AR, Rodrigues AL. Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 994-9. PMID 18289757 DOI: 10.1016/j.pnpbp.2008.01.012  0.44
2008 Franco JL, Posser T, Brocardo PS, Trevisan R, Uliano-Silva M, Gabilan NH, Santos AR, Leal RB, Rodrigues AL, Farina M, Dafre AL. Involvement of glutathione, ERK1/2 phosphorylation and BDNF expression in the antidepressant-like effect of zinc in rats. Behavioural Brain Research. 188: 316-23. PMID 18191237 DOI: 10.1016/j.bbr.2007.11.012  0.44
2008 Soldi C, Pizzolatti MG, Luiz AP, Marcon R, Meotti FC, Mioto LA, Santos AR. Synthetic derivatives of the alpha- and beta-amyrin triterpenes and their antinociceptive properties. Bioorganic & Medicinal Chemistry. 16: 3377-86. PMID 18160299 DOI: 10.1016/j.bmc.2007.12.008  0.4
2008 Brocardo PS, Budni J, Kaster MP, Santos AR, Rodrigues AL. Folic acid administration produces an antidepressant-like effect in mice: evidence for the involvement of the serotonergic and noradrenergic systems. Neuropharmacology. 54: 464-73. PMID 18078962 DOI: 10.1016/J.Neuropharm.2007.10.016  0.68
2008 Quintão NL, Santos AR, Campos MM, Calixto JB. The role of neurotrophic factors in genesis and maintenance of mechanical hypernociception after brachial plexus avulsion in mice. Pain. 136: 125-33. PMID 17706869 DOI: 10.1016/J.Pain.2007.06.027  0.68
2007 Franco JL, Braga HC, Stringari J, Missau FC, Posser T, Mendes BG, Leal RB, Santos AR, Dafre AL, Pizzolatti MG, Farina M. Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin. Chemical Research in Toxicology. 20: 1919-26. PMID 17944542 DOI: 10.1021/tx7002323  0.4
2007 Lapa Fda R, Freitas CS, Baggio CH, Missau FC, Pizzolatti MG, Santos AR, Marques MC. Gastroprotective activity of the hydroalcoholic extract obtained from Polygala paniculata L. in rats. The Journal of Pharmacy and Pharmacology. 59: 1413-9. PMID 17910817 DOI: 10.1211/jpp.59.10.0012  0.4
2007 Luiz AP, Moura JD, Meotti FC, Guginski G, Guimarães CL, Azevedo MS, Rodrigues AL, Santos AR. Antinociceptive action of ethanolic extract obtained from roots of Humirianthera ampla Miers. Journal of Ethnopharmacology. 114: 355-63. PMID 17900839 DOI: 10.1016/j.jep.2007.08.016  0.44
2007 Andrade EL, Ferreira J, Santos AR, Calixto JB. Pharmacological analysis of paregoric elixir and its constituents: in vitro and in vivo studies. Journal of Ethnopharmacology. 114: 218-26. PMID 17869462 DOI: 10.1016/J.Jep.2007.08.004  0.68
2007 Kaster MP, Budni J, Santos AR, Rodrigues AL. Pharmacological evidence for the involvement of the opioid system in the antidepressant-like effect of adenosine in the mouse forced swimming test. European Journal of Pharmacology. 576: 91-8. PMID 17868670 DOI: 10.1016/J.Ejphar.2007.08.026  0.68
2007 Budni J, Gadotti VM, Kaster MP, Santos AR, Rodrigues AL. Role of different types of potassium channels in the antidepressant-like effect of agmatine in the mouse forced swimming test. European Journal of Pharmacology. 575: 87-93. PMID 17761162 DOI: 10.1016/J.Ejphar.2007.08.010  0.68
2007 Meotti FC, Posser T, Missau FC, Pizzolatti MG, Leal RB, Santos AR. Involvement of p38MAPK on the antinociceptive action of myricitrin in mice. Biochemical Pharmacology. 74: 924-31. PMID 17678631 DOI: 10.1016/j.bcp.2007.06.024  0.4
2007 Lucena GM, Franco JL, Ribas CM, Azevedo MS, Meotti FC, Gadotti VM, Dafre AL, Santos AR, Farina M. Cipura paludosa extract prevents methyl mercury-induced neurotoxicity in mice. Basic & Clinical Pharmacology & Toxicology. 101: 127-31. PMID 17651315 DOI: 10.1111/j.1742-7843.2007.00091.x  0.56
2007 Paszcuk AF, Gadotti VM, Tibola D, Quintão NL, Rodrigues AL, Calixto JB, Santos AR. Anti-hypernociceptive properties of agmatine in persistent inflammatory and neuropathic models of pain in mice. Brain Research. 1159: 124-33. PMID 17573052 DOI: 10.1016/J.Brainres.2007.04.050  0.68
2006 DalBó S, Jürgensen S, Horst H, Soethe DN, Santos AR, Pizzolatti MG, Ribeiro-do-Valle RM. Analysis of the antinociceptive effect of the proanthocyanidin-rich fraction obtained from Croton celtidifolius barks: evidence for a role of the dopaminergic system. Pharmacology, Biochemistry, and Behavior. 85: 317-23. PMID 17030059 DOI: 10.1016/j.pbb.2006.08.014  0.68
2006 Mantovani M, Kaster MP, Pertile R, Calixto JB, Rodrigues AL, Santos AR. Mechanisms involved in the antinociception caused by melatonin in mice. Journal of Pineal Research. 41: 382-9. PMID 17014696 DOI: 10.1111/J.1600-079X.2006.00380.X  0.68
2006 Gadotti VM, Tibola D, Paszcuk AF, Rodrigues AL, Calixto JB, Santos AR. Contribution of spinal glutamatergic receptors to the antinociception caused by agmatine in mice. Brain Research. 1093: 116-22. PMID 16765330 DOI: 10.1016/J.Brainres.2006.03.087  0.68
2006 Quintão NL, Balz D, Santos AR, Campos MM, Calixto JB. Long-lasting neuropathic pain induced by brachial plexus injury in mice: Role triggered by the pro-inflammatory cytokine, tumour necrosis factor alpha. Neuropharmacology. 50: 614-20. PMID 16386767 DOI: 10.1016/J.Neuropharm.2005.11.007  0.68
2006 Meotti FC, Luiz AP, Pizzolatti MG, Kassuya CA, Calixto JB, Santos AR. Analysis of the antinociceptive effect of the flavonoid myricitrin: evidence for a role of the L-arginine-nitric oxide and protein kinase C pathways. The Journal of Pharmacology and Experimental Therapeutics. 316: 789-96. PMID 16260583 DOI: 10.1124/Jpet.105.092825  0.68
2005 Quintão NL, Medeiros R, Santos AR, Campos MM, Calixto JB. The effects of diacerhein on mechanical allodynia in inflammatory and neuropathic models of nociception in mice. Anesthesia and Analgesia. 101: 1763-9. PMID 16301256 DOI: 10.1213/01.Ane.0000184182.03203.61  0.68
2005 Campos MM, Fernandes ES, Ferreira J, Santos AR, Calixto JB. Antidepressant-like effects of Trichilia catigua (Catuaba) extract: evidence for dopaminergic-mediated mechanisms. Psychopharmacology. 182: 45-53. PMID 15991001 DOI: 10.1007/S00213-005-0052-1  0.68
2005 DalBó S, Jürgensen S, Horst H, Ruzza AA, Soethe DN, Santos AR, Pizzolatti MG, Ribeiro-do-Valle RM. Antinociceptive effect of proanthocyanidins from Croton celtidifolius bark. The Journal of Pharmacy and Pharmacology. 57: 765-71. PMID 15969932 DOI: 10.1211/0022357056091  0.4
2005 Rosa KA, Gadotti VM, Rosa AO, Rodrigues AL, Calixto JB, Santos AR. Evidence for the involvement of glutamatergic system in the antinociceptive effect of ascorbic acid. Neuroscience Letters. 381: 185-8. PMID 15882814 DOI: 10.1016/J.Neulet.2005.02.032  0.68
2005 Santos AR, Gadotti VM, Oliveira GL, Tibola D, Paszcuk AF, Neto A, Spindola HM, Souza MM, Rodrigues AL, Calixto JB. Mechanisms involved in the antinociception caused by agmatine in mice. Neuropharmacology. 48: 1021-34. PMID 15857629 DOI: 10.1016/J.Neuropharm.2005.01.012  0.68
2005 Otuki MF, Ferreira J, Lima FV, Meyre-Silva C, Malheiros A, Muller LA, Cani GS, Santos AR, Yunes RA, Calixto JB. Antinociceptive properties of mixture of alpha-amyrin and beta-amyrin triterpenes: evidence for participation of protein kinase C and protein kinase A pathways. The Journal of Pharmacology and Experimental Therapeutics. 313: 310-8. PMID 15626726 DOI: 10.1124/Jpet.104.071779  0.68
2004 Dias Elpo Zomkowski A, Oscar Rosa A, Lin J, Santos AR, Calixto JB, Lúcia Severo Rodrigues A. Evidence for serotonin receptor subtypes involvement in agmatine antidepressant like-effect in the mouse forced swimming test. Brain Research. 1023: 253-63. PMID 15374751 DOI: 10.1016/J.Brainres.2004.07.041  0.76
2004 Campos MM, Fernandes ES, Ferreira J, Bortolanza LB, Santos AR, Calixto JB. Pharmacological and neurochemical evidence for antidepressant-like effects of the herbal product Catuama. Pharmacology, Biochemistry, and Behavior. 78: 757-64. PMID 15301932 DOI: 10.1016/J.Pbb.2004.05.024  0.68
2004 Rodrigues-Filho R, Campos MM, Ferreira J, Santos AR, Bertelli JA, Calixto JB. Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain. Brain Research. 1018: 159-70. PMID 15276874 DOI: 10.1016/J.Brainres.2004.05.058  0.68
2004 Bertelli JA, dos Santos AR, Taleb M, Calixto JB, Mira JC, Ghizoni MF. Long interpositional nerve graft consistently induces incomplete motor and sensory recovery in the rat. An experimental model to test nerve repair. Journal of Neuroscience Methods. 134: 75-80. PMID 15102505 DOI: 10.1016/J.Jneumeth.2003.11.002  0.76
2004 Calixto JB, Campos MM, Otuki MF, Santos AR. Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules. Planta Medica. 70: 93-103. PMID 14994184 DOI: 10.1055/S-2004-815483  0.68
2003 Calixto JB, Otuki MF, Santos AR. Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor kappa B (NF-kappaB). Planta Medica. 69: 973-83. PMID 14735432 DOI: 10.1055/S-2003-45141  0.68
2003 Rosa AO, Lin J, Calixto JB, Santos AR, Rodrigues AL. Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice. Behavioural Brain Research. 144: 87-93. PMID 12946598 DOI: 10.1016/S0166-4328(03)00069-X  0.68
2003 Rodrigues-Filho R, Santos AR, Bertelli JA, Calixto JB. Avulsion injury of the rat brachial plexus triggers hyperalgesia and allodynia in the hindpaws: a new model for the study of neuropathic pain. Brain Research. 982: 186-94. PMID 12915254 DOI: 10.1016/S0006-8993(03)03007-5  0.68
2003 Mantovani M, Pértile R, Calixto JB, Santos AR, Rodrigues AL. Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway. Neuroscience Letters. 343: 1-4. PMID 12749983 DOI: 10.1016/S0304-3940(03)00306-9  0.68
2003 Beirith A, Santos AR, Calixto JB. The role of neuropeptides and capsaicin-sensitive fibres in glutamate-induced nociception and paw oedema in mice. Brain Research. 969: 110-6. PMID 12676371 DOI: 10.1016/S0006-8993(03)02286-8  0.68
2003 Lunardi F, Guzela M, Rodrigues AT, Corrêa R, Eger-Mangrich I, Steindel M, Grisard EC, Assreuy J, Calixto JB, Santos AR. Trypanocidal and leishmanicidal properties of substitution-containing chalcones. Antimicrobial Agents and Chemotherapy. 47: 1449-51. PMID 12654691 DOI: 10.1128/Aac.47.4.1449-1451.2003  0.68
2001 Calixto JB, Scheidt C, Otuki M, Santos AR. Biological activity of plant extracts: novel analgesic drugs. Expert Opinion On Emerging Drugs. 6: 261-79. PMID 15989526 DOI: 10.1517/14728214.6.2.261  0.76
2000 Santos AR, De Campos RO, Miguel OG, Filho VC, Siani AC, Yunes RA, Calixto JB. Antinociceptive properties of extracts of new species of plants of the genus Phyllanthus (Euphorbiaceae). Journal of Ethnopharmacology. 72: 229-38. PMID 10967476 DOI: 10.1016/S0378-8741(00)00256-7  0.76
2000 Calixto JB, Beirith A, Ferreira J, Santos AR, Filho VC, Yunes RA. Naturally occurring antinociceptive substances from plants. Phytotherapy Research : Ptr. 14: 401-18. PMID 10960893 DOI: 10.1002/1099-1573(200009)14:6<401::Aid-Ptr762>3.0.Co;2-H  0.76
2000 Ferreira J, Floriani AE, Filho VC, Delle Monache F, Yunes RA, Calixto JB, Santos AR. Antinociceptive properties of the methanolic extract and two triterpenes isolated from Epidendrum Mosenii stems (Orchidaceae). Life Sciences. 66: 791-802. PMID 10698354 DOI: 10.1016/S0024-3205(99)00652-9  0.76
1999 Ferreira J, Santos AR, Calixto JB. Antinociception produced by systemic, spinal and supraspinal administration of amiloride in mice. Life Sciences. 65: 1059-66. PMID 10499873 DOI: 10.1016/S0024-3205(99)00336-7  0.76
1999 Santos AR, De Campos RO, Miguel OG, Cechinel-Filho V, Yunes RA, Calixto JB. The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester. European Journal of Pharmacology. 379: 7-17. PMID 10499367 DOI: 10.1016/S0014-2999(99)00490-2  0.76
1999 Trentin AP, Santos AR, Guedes A, Pizzolatti MG, Yunes RA, Calixto JB. Antinociception caused by the extract of Hedyosmum brasiliense and its active principle, the sesquiterpene lactone 13-hydroxy-8,9-dehydroshizukanolide. Planta Medica. 65: 517-21. PMID 10483370 DOI: 10.1055/S-1999-14007  0.68
1999 Beirith A, Santos AR, Calixto JB, Hess SC, Messana I, Ferrari F, Yunes RA. Study of the antinociceptive action of the ethanolic extract and the triterpene 24-hydroxytormentic acid isolated from the stem bark of Ocotea suaveolens. Planta Medica. 65: 50-5. PMID 10083846 DOI: 10.1055/S-1999-13962  0.76
1998 Cechinel-Filho V, Santos AR, Calixto JB, Delle-Monache F, Miguel OG, Yunes RA. Triterpenes from Phyllanthus sellowianus roots. Planta Medica. 64: 194. PMID 17253237 DOI: 10.1055/S-2006-957406  0.76
1998 Cechinel Filho V, Schlemper V, Santos AR, Pinheiro TR, Yunes RA, Mendes GL, Calixto JB, Delle Monache F. Isolation and identification of active compounds from Drimys winteri barks. Journal of Ethnopharmacology. 62: 223-7. PMID 9849632 DOI: 10.1016/S0378-8741(98)00069-5  0.76
1998 Mendes GL, Santos AR, Campos MM, Tratsk KS, Yunes RA, Cechinel Filho V, Calixto JB. Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae). Life Sciences. 63: 369-81. PMID 9714424 DOI: 10.1016/S0024-3205(98)00285-9  0.76
1998 Beirith A, Santos AR, Rodrigues AL, Creczynski-Pasa TB, Calixto JB. Spinal and supraspinal antinociceptive action of dipyrone in formalin, capsaicin and glutamate tests. Study of the mechanism of action. European Journal of Pharmacology. 345: 233-45. PMID 9592021 DOI: 10.1016/S0014-2999(98)00026-0  0.76
1997 de Campos RO, Santos AR, Vaz ZR, Pinheiro TR, Pizzolatti MG, Cechinel Filho V, Delle Monache F, Yunes RA, Calixto JB. Antinociceptive properties of the hydroalcoholic extract and preliminary study of a xanthone isolated from Polygala cyparissias (Polygalaceae). Life Sciences. 61: 1619-30. PMID 9353171 DOI: 10.1016/S0024-3205(97)00741-8  0.76
1997 Trentin AP, Santos AR, Miguel OG, Pizzolatti MG, Yunes RA, Calixto JB. Mechanisms involved in the antinociceptive effect in mice of the hydroalcoholic extract of Siphocampylus verticillatus. The Journal of Pharmacy and Pharmacology. 49: 567-72. PMID 9178196 DOI: 10.1111/J.2042-7158.1997.Tb06843.X  0.68
1996 Teixeira RM, Santos AR, Ribeiro SJ, Calixto JB, Rae GA, De Lima TC. Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice. European Journal of Pharmacology. 311: 7-14. PMID 8884230 DOI: 10.1016/0014-2999(96)00390-1  0.76
1996 Miguel OG, Calixto JB, Santos AR, Messana I, Ferrari F, Cechinel Filho V, Pizzolatti MG, Yunes RA. Chemical and preliminary analgesic evaluation of geraniin and furosin isolated from Phyllanthus sellowianus. Planta Medica. 62: 146-9. PMID 8657748 DOI: 10.1055/S-2006-957838  0.76
1995 Miguel OG, Filho VC, Pizzolatti MG, Santos AR, Calixto JB, Ferrari F, Messana I, Yunes RA. A triterpene and phenolic compounds from leaves and stems of Phyllanthus sellowianus. Planta Medica. 61: 391. PMID 17238095 DOI: 10.1055/S-2006-958120  0.76
1995 Santos AR, Filho VC, Yunes RA, Calixto JB. Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus. General Pharmacology. 26: 1499-1506. PMID 8690236 DOI: 10.1016/0306-3623(95)00030-5  0.76
1995 Santos AR, Niero R, Filho VC, Yunes RA, Pizzolatti MG, Delle Monache F, Calixto JB. Antinociceptive properties of steroids isolated from Phyllanthus corcovadensis in mice. Planta Medica. 61: 329-32. PMID 7480179 DOI: 10.1055/s-2006-958093  0.76
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