Theodore G. Wensel, PhD - Publications

Affiliations: 
1988- Biochemistry and Molecular Biology Baylor College of Medicine, Houston, TX 
Area:
retina, TRP channels, RGS proteins, GPCR (dopamine, mGluR),fluorescence spectroscopy and microscopy, lanthanide luminscence, cryo-EM
Website:
http://ncmi.bcm.edu/homes/wensellab

141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Dosey TL, Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W, Wensel TG. Structures of TRPV2 in distinct conformations provide insight into role of the pore turret. Nature Structural & Molecular Biology. PMID 30598551 DOI: 10.1038/s41594-018-0168-8  1
2018 Agosto MA, Anastassov IA, Robichaux MA, Wensel TG. A Large Endoplasmic Reticulum-Resident Pool of TRPM1 in Retinal ON-Bipolar Cells. Eneuro. 5. PMID 30027108 DOI: 10.1523/ENEURO.0143-18.2018  1
2018 Dharmat R, Eblimit A, Robichaux MA, Zhang Z, Nguyen TT, Jung SY, He F, Jain A, Li Y, Qin J, Overbeek P, Roepman R, Mardon G, Wensel TG, Chen R. SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium. The Journal of Cell Biology. PMID 29899041 DOI: 10.1083/jcb.201712117  1
2018 Yu B, Egbejimi A, Dharmat R, Xu P, Zhao Z, Long B, Miao H, Chen R, Wensel TG, Cai J, Chen Y. Phagocytosed photoreceptor outer segments activate mTORC1 in the retinal pigment epithelium. Science Signaling. 11. PMID 29844054 DOI: 10.1126/scisignal.aag3315  1
2018 Agosto MA, Anastassov IA, Wensel TG. Differential epitope masking reveals synapse-specific complexes of TRPM1. Visual Neuroscience. 35: E001. PMID 29370879 DOI: 10.1017/S0952523817000360  1
2017 Tse DY, Kim SJ, Chung I, He F, Wensel TG, Wu SM. The ocular toxicity and pharmacokinetics of simvastatin following intravitreal injection in mice. International Journal of Ophthalmology. 10: 1361-1369. PMID 28944193 DOI: 10.18240/ijo.2017.09.05  1
2017 Galaz-Montoya M, Wright SJ, Rodriguez GJ, Lichtarge O, Wensel TG. Beta-2 Adrenergic Receptor Activation Mobilizes Intracellular Calcium via a Non-Canonical cAMP-Independent Signaling Pathway. The Journal of Biological Chemistry. PMID 28442571 DOI: 10.1074/jbc.M117.787119  1
2016 Wensel TG, Zhang Z, Anastassov IA, Gilliam JC, He F, Schmid MF, Robichaux MA. Structural and molecular bases of rod photoreceptor morphogenesis and disease. Progress in Retinal and Eye Research. PMID 27352937 DOI: 10.1016/j.preteyeres.2016.06.002  1
2016 He F, Agosto MA, Anastassov IA, Tse DY, Wu SM, Wensel TG. Phosphatidylinositol-3-phosphate is light-regulated and essential for survival in retinal rods. Scientific Reports. 6: 26978. PMID 27245220 DOI: 10.1038/srep26978  1
2016 Sung YM, Wilkins AD, Rodriguez GJ, Wensel TG, Lichtarge O. Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26979958 DOI: 10.1073/pnas.1516579113  1
2016 Zhao L, Chen Y, Bajaj AO, Eblimit A, Xu M, Soens ZT, Wang F, Ge Z, Jung SY, He F, Li Y, Wensel TG, Qin J, Chen R. Integrative subcellular proteomic analysis allows accurate prediction of human disease causing genes. Genome Research. PMID 26912414 DOI: 10.1101/gr.198911.115  1
2015 Roman-Sanchez R, Wensel TG, Wilson JH. Nonsense mutations in the rhodopsin gene that give rise to mild phenotypes trigger mRNA degradation in human cells by nonsense-mediated decay. Experimental Eye Research. PMID 26416182 DOI: 10.1016/j.exer.2015.09.013  1
2015 Zhang Z, He F, Constantine R, Baker ML, Baehr W, Schmid MF, Wensel TG, Agosto MA. Domain organization and conformational plasticity of the G protein effector, PDE6. The Journal of Biological Chemistry. 290: 17131-2. PMID 26163476 DOI: 10.1074/jbc.A115.647636  1
2015 Wang S, Tan KL, Agosto MA, Xiong B, Yamamoto S, Sandoval H, Jaiswal M, Bayat V, Zhang K, Charng WL, David G, Duraine L, Venkatachalam K, Wensel TG, Bellen HJ. Correction: the retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration. Plos Biology. 13: e1002170. PMID 26020534 DOI: 10.1371/journal.pbio.1002170  1
2015 Zhang Z, He F, Constantine R, Baker ML, Baehr W, Schmid MF, Wensel TG, Agosto MA. Domain organization and conformational plasticity of the G protein effector, PDE6. The Journal of Biological Chemistry. 290: 12833-43. PMID 25809480 DOI: 10.1074/jbc.M115.647636  1
2015 Wensel TG, Gilliam JC. Three-dimensional architecture of murine rod cilium revealed by cryo-EM. Methods in Molecular Biology (Clifton, N.J.). 1271: 267-92. PMID 25697530 DOI: 10.1007/978-1-4939-2330-4_18  1
2015 Kang HJ, Wilkins AD, Lichtarge O, Wensel TG. Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors. The Journal of Biological Chemistry. 290: 2870-8. PMID 25519912 DOI: 10.1074/jbc.M114.622233  1
2014 Sandoval IM, Price BA, Gross AK, Chan F, Sammons JD, Wilson JH, Wensel TG. Abrupt onset of mutations in a developmentally regulated gene during terminal differentiation of post-mitotic photoreceptor neurons in mice. Plos One. 9: e108135. PMID 25264759 DOI: 10.1371/journal.pone.0108135  1
2014 Kang HJ, Menlove K, Ma J, Wilkins A, Lichtarge O, Wensel TG. Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels. The Journal of Biological Chemistry. 289: 29961-74. PMID 25193666 DOI: 10.1074/jbc.M114.574483  1
2014 Agosto MA, Zhang Z, He F, Anastassov IA, Wright SJ, McGehee J, Wensel TG. Oligomeric state of purified transient receptor potential melastatin-1 (TRPM1), a protein essential for dim light vision. The Journal of Biological Chemistry. 289: 27019-33. PMID 25112866 DOI: 10.1074/jbc.M114.593780  1
2014 Wang S, Tan KL, Agosto MA, Xiong B, Yamamoto S, Sandoval H, Jaiswal M, Bayat V, Zhang K, Charng WL, David G, Duraine L, Venkatachalam K, Wensel TG, Bellen HJ. The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration. Plos Biology. 12: e1001847. PMID 24781186 DOI: 10.1371/journal.pbio.1001847  1
2013 Arshavsky VY, Wensel TG. Timing is everything: GTPase regulation in phototransduction. Investigative Ophthalmology & Visual Science. 54: 7725-33. PMID 24265205 DOI: 10.1167/iovs.13-13281  1
2012 Price BA, Sandoval IM, Chan F, Nichols R, Roman-Sanchez R, Wensel TG, Wilson JH. Rhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutant. Plos One. 7: e49889. PMID 23185477 DOI: 10.1371/journal.pone.0049889  1
2012 Gilliam JC, Chang JT, Sandoval IM, Zhang Y, Li T, Pittler SJ, Chiu W, Wensel TG. Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration. Cell. 151: 1029-41. PMID 23178122 DOI: 10.1016/j.cell.2012.10.038  1
2012 Wensel TG. Molecular Biology of Vision Basic Neurochemistry. 889-903. DOI: 10.1016/B978-0-12-374947-5.00051-1  1
2011 Price BA, Sandoval IM, Chan F, Simons DL, Wu SM, Wensel TG, Wilson JH. Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa. Investigative Ophthalmology & Visual Science. 52: 9728-36. PMID 22110080 DOI: 10.1167/iovs.11-8654  1
2011 Gilliam JC, Wensel TG. TRP channel gene expression in the mouse retina. Vision Research. 51: 2440-52. PMID 22037305 DOI: 10.1016/j.visres.2011.10.009  1
2011 Chan F, Hauswirth WW, Wensel TG, Wilson JH. Efficient mutagenesis of the rhodopsin gene in rod photoreceptor neurons in mice. Nucleic Acids Research. 39: 5955-66. PMID 21478169 DOI: 10.1093/nar/gkr196  1
2011 Moiseenkova-Bell V, Wensel TG. Functional and structural studies of TRP channels heterologously expressed in budding yeast. Advances in Experimental Medicine and Biology. 704: 25-40. PMID 21290288 DOI: 10.1007/978-94-007-0265-3_2  1
2011 Baehr W, Wensel T, Hageman G, Wu S, Zack D. Retinal ganglion cells: development, function, and disease. Vision Research. 51: 223. PMID 21251506 DOI: 10.1016/j.visres.2011.01.005  1
2010 Mojumder DK, Concepcion FA, Patel SK, Barkmeier AJ, Carvounis PE, Wilson JH, Holz ER, Wensel TG. Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Investigative Ophthalmology & Visual Science. 51: 5796-803. PMID 20505203 DOI: 10.1167/iovs.10-5541  1
2010 Rodriguez GJ, Yao R, Lichtarge O, Wensel TG. Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors. Proceedings of the National Academy of Sciences of the United States of America. 107: 7787-92. PMID 20385837 DOI: 10.1073/pnas.0914877107  1
2010 Budzynski E, Gross AK, McAlear SD, Peachey NS, Shukla M, He F, Edwards M, Won J, Hicks WL, Wensel TG, Naggert JK, Nishina PM. Mutations of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice. The Journal of Biological Chemistry. 285: 14521-33. PMID 20207741 DOI: 10.1074/jbc.M110.112409  1
2010 Jeffrey BG, Morgans CW, Puthussery T, Wensel TG, Burke NS, Brown RL, Duvoisin RM. R9AP stabilizes RGS11-G beta5 and accelerates the early light response of ON-bipolar cells. Visual Neuroscience. 27: 9-17. PMID 20100392 DOI: 10.1017/S0952523809990319  1
2010 Mancuso JJ, Qian Y, Long C, Wu GY, Wensel TG. Distribution of RGS9-2 in neurons of the mouse striatum. Journal of Neurochemistry. 112: 651-61. PMID 19912469 DOI: 10.1111/j.1471-4159.2009.06488.x  1
2010 Mojumder DK, Wensel TG. Topical mydriatics affect light-evoked retinal responses in anesthetized mice. Investigative Ophthalmology & Visual Science. 51: 567-76. PMID 19661232 DOI: 10.1167/iovs.09-4168  1
2010 Rodriguez GJ, Yao R, Lichtarge O, Wensel TG. Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors (Proceedings of the National Academy of Sciences of the United States of America (2010), 107, 17, (7787-7792) DOI: 10.1073/pnas.0914877107) Proceedings of the National Academy of Sciences of the United States of America. 107. DOI: 10.1073/pnas.1005260107  1
2010 Baehr W, Hageman G, Wensel T, Wu S, Zack D. Mechanisms of macular degeneration Vision Research. 50: 637. DOI: 10.1016/j.visres.2010.02.007  1
2010 Rodriguez GJ, Yao R, Lichtarge O, Wensel TG. Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 17 (7787-7792) DOI: 10.1073/pnas.0914877107) Proceedings of the National Academy of Sciences of the United States of America. 107: 9476.  1
2009 Yao CK, Lin YQ, Ly CV, Ohyama T, Haueter CM, Moiseenkova-Bell VY, Wensel TG, Bellen HJ. A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis. Cell. 138: 947-60. PMID 19737521 DOI: 10.1016/j.cell.2009.06.033  1
2009 Mancuso JJ, Larson AM, Wensel TG, Saggau P. Multiphoton adaptation of a commercial low-cost confocal microscope for live tissue imaging. Journal of Biomedical Optics. 14: 034048. PMID 19566340 DOI: 10.1117/1.3139850  1
2009 Mojumder DK, Qian Y, Wensel TG. Two R7 regulator of G-protein signaling proteins shape retinal bipolar cell signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7753-65. PMID 19535587 DOI: 10.1523/JNEUROSCI.1794-09.2009  1
2009 Moiseenkova-Bell VY, Wensel TG. Hot on the trail of TRP channel structure. The Journal of General Physiology. 133: 239-44. PMID 19237588 DOI: 10.1085/jgp.200810123  1
2009 Sakamoto K, McCluskey M, Wensel TG, Naggert JK, Nishina PM. New mouse models for recessive retinitis pigmentosa caused by mutations in the Pde6a gene. Human Molecular Genetics. 18: 178-92. PMID 18849587 DOI: 10.1093/hmg/ddn327  1
2008 Mojumder DK, Wensel TG, Frishman LJ. Subcellular compartmentalization of two calcium binding proteins, calretinin and calbindin-28 kDa, in ganglion and amacrine cells of the rat retina. Molecular Vision. 14: 1600-13. PMID 18769561  1
2008 Wang Q, Zhang X, Zhang L, He F, Zhang G, Jamrich M, Wensel TG. Activation-dependent hindrance of photoreceptor G protein diffusion by lipid microdomains. The Journal of Biological Chemistry. 283: 30015-24. PMID 18713731 DOI: 10.1074/jbc.M803953200  1
2008 Moiseenkova-Bell VY, Stanciu LA, Serysheva II, Tobe BJ, Wensel TG. Structure of TRPV1 channel revealed by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America. 105: 7451-5. PMID 18490661 DOI: 10.1073/pnas.0711835105  1
2008 Benfield AP, Macleod MC, Liu Y, Wu Q, Wensel TG, Vasquez KM. Targeted generation of DNA strand breaks using pyrene-conjugated triplex-forming oligonucleotides. Biochemistry. 47: 6279-88. PMID 18473480 DOI: 10.1021/bi7024029  1
2008 Jedema HP, Gold SJ, Gonzalez-Burgos G, Sved AF, Tobe BJ, Wensel T, Grace AA. Chronic cold exposure increases RGS7 expression and decreases alpha(2)-autoreceptor-mediated inhibition of noradrenergic locus coeruleus neurons. The European Journal of Neuroscience. 27: 2433-43. PMID 18461718 DOI: 10.1111/j.1460-9568.2008.06208.x  1
2008 Wensel TG. Signal transducing membrane complexes of photoreceptor outer segments. Vision Research. 48: 2052-61. PMID 18456304 DOI: 10.1016/j.visres.2008.03.010  1
2008 Abd-El-Barr MM, Albini TA, Carvounis PE, He F, Manzano RP, Chevez-Barrios P, Wensel TG, Wu SM, Holz ER. Safety and pharmokinetics of triamcinolone hexacetonide in rabbit eyes. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 24: 197-205. PMID 18355133 DOI: 10.1089/jop.2007.0103  1
2007 Morgans CW, Wensel TG, Brown RL, Perez-Leon JA, Bearnot B, Duvoisin RM. Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells. The European Journal of Neuroscience. 26: 2899-905. PMID 18001285 DOI: 10.1111/j.1460-9568.2007.05867.x  1
2007 Khajavi M, Shiga K, Wiszniewski W, He F, Shaw CA, Yan J, Wensel TG, Snipes GJ, Lupski JR. Oral curcumin mitigates the clinical and neuropathologic phenotype of the Trembler-J mouse: a potential therapy for inherited neuropathy. American Journal of Human Genetics. 81: 438-53. PMID 17701891 DOI: 10.1086/519926  1
2007 Marc RE, Jones BW, Anderson JR, Kinard K, Marshak DW, Wilson JH, Wensel T, Lucas RJ. Neural reprogramming in retinal degeneration. Investigative Ophthalmology & Visual Science. 48: 3364-71. PMID 17591910 DOI: 10.1167/iovs.07-0032  1
2007 Song JH, Song H, Wensel TG, Sokolov M, Martemyanov KA. Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. Molecular and Cellular Neurosciences. 35: 311-9. PMID 17442586 DOI: 10.1016/j.mcn.2007.03.006  1
2006 Gross AK, Decker G, Chan F, Sandoval IM, Wilson JH, Wensel TG. Defective development of photoreceptor membranes in a mouse model of recessive retinal degeneration. Vision Research. 46: 4510-8. PMID 16979686 DOI: 10.1016/j.visres.2006.07.012  1
2006 Krispel CM, Chen D, Melling N, Chen YJ, Martemyanov KA, Quillinan N, Arshavsky VY, Wensel TG, Chen CK, Burns ME. RGS expression rate-limits recovery of rod photoresponses. Neuron. 51: 409-16. PMID 16908407 DOI: 10.1016/j.neuron.2006.07.010  1
2006 Meltzer RH, Lurtz MM, Wensel TG, Pedersen SE. Nicotinic acetylcholine receptor channel electrostatics determined by diffusion-enhanced luminescence energy transfer. Biophysical Journal. 91: 1315-24. PMID 16751249 DOI: 10.1529/biophysj.106.081448  1
2006 Meltzer RH, Thompson E, Soman KV, Song XZ, Ebalunode JO, Wensel TG, Briggs JM, Pedersen SE. Electrostatic steering at acetylcholine binding sites. Biophysical Journal. 91: 1302-14. PMID 16751247 DOI: 10.1529/biophysj.106.081463  1
2006 Zhang X, Wensel TG, Yuan C. Tokay gecko photoreceptors achieve rod-like physiology with cone-like proteins. Photochemistry and Photobiology. 82: 1452-60. PMID 16553462 DOI: 10.1562/2006-01-05-RA-767  1
2006 Iyer MN, He F, Wensel TG, Mieler WF, Benz MS, Holz ER. Clearance of intravitreal moxifloxacin. Investigative Ophthalmology & Visual Science. 47: 317-9. PMID 16384979 DOI: 10.1167/iovs.05-1124  1
2005 Iyer MN, He F, Wensel TG, Mieler WF, Benz MS, Holz ER. Intravitreal clearance of moxifloxacin. Transactions of the American Ophthalmological Society. 103: 76-81; discussion 81. PMID 17057790  1
2005 Wensel TG, Gross AK, Chan F, Sykoudis K, Wilson JH. Rhodopsin-EGFP knock-ins for imaging quantal gene alterations. Vision Research. 45: 3445-53. PMID 16139321 DOI: 10.1016/j.visres.2005.07.016  1
2005 Wiszniewski W, Zaremba CM, Yatsenko AN, Jamrich M, Wensel TG, Lewis RA, Lupski JR. ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies. Human Molecular Genetics. 14: 2769-78. PMID 16103129 DOI: 10.1093/hmg/ddi310  1
2005 Wensel TG, He F, Malinski JA. Purification, reconstitution on lipid vesicles, and assays of PDE6 and its activator G protein, transducin. Methods in Molecular Biology (Clifton, N.J.). 307: 289-313. PMID 15988071 DOI: 10.1385/1-59259-839-0:289  1
2004 Hu G, Wensel TG. Characterization of R9AP, a membrane anchor for the photoreceptor GTPase-accelerating protein, RGS9-1. Methods in Enzymology. 390: 178-96. PMID 15488178 DOI: 10.1016/S0076-6879(04)90012-2  1
2004 Chan F, Bradley A, Wensel TG, Wilson JH. Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 101: 9109-14. PMID 15184660 DOI: 10.1073/pnas.0403149101  1
2004 Zhang Z, Melia TJ, He F, Yuan C, McGough A, Schmid MF, Wensel TG. How a G protein binds a membrane. The Journal of Biological Chemistry. 279: 33937-45. PMID 15173184 DOI: 10.1074/jbc.M403404200  1
2004 He F, Mao M, Wensel TG. Enhancement of phototransduction g protein-effector interactions by phosphoinositides. The Journal of Biological Chemistry. 279: 8986-90. PMID 14699118 DOI: 10.1074/jbc.M311488200  1
2004 Madabushi S, Gross AK, Philippi A, Meng EC, Wensel TG, Lichtarge O. Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions. The Journal of Biological Chemistry. 279: 8126-32. PMID 14660595 DOI: 10.1074/jbc.M312671200  1
2003 Wilson JH, Wensel TG. The nature of dominant mutations of rhodopsin and implications for gene therapy. Molecular Neurobiology. 28: 149-58. PMID 14576453 DOI: 10.1385/MN:28:2:149  1
2003 Zhang L, El-Hodiri HM, Ma HF, Zhang X, Servetnick M, Wensel TG, Jamrich M. Targeted expression of the dominant-negative FGFR4a in the eye using Xrx1A regulatory sequences interferes with normal retinal development. Development (Cambridge, England). 130: 4177-86. PMID 12874136 DOI: 10.1242/dev.00626  1
2003 Burns ME, Wensel TG. From molecules to behavior: new clues for RGS function in the striatum. Neuron. 38: 853-6. PMID 12818171 DOI: 10.1016/S0896-6273(03)00361-1  1
2003 Chen CK, Eversole-Cire P, Zhang H, Mancino V, Chen YJ, He W, Wensel TG, Simon MI. Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5. Proceedings of the National Academy of Sciences of the United States of America. 100: 6604-9. PMID 12738888 DOI: 10.1073/pnas.0631825100  1
2003 Kennedy MJ, Sowa ME, Wensel TG, Hurley JB. Acceleration of key reactions as a strategy to elucidate the rate-limiting chemistry underlying phototransduction inactivation. Investigative Ophthalmology & Visual Science. 44: 1016-22. PMID 12601023  0.48
2003 Zhang X, Wensel TG, Kraft TW. GTPase regulators and photoresponses in cones of the eastern chipmunk. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1287-97. PMID 12598617  1
2003 Hu G, Zhang Z, Wensel TG. Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP. The Journal of Biological Chemistry. 278: 14550-4. PMID 12560335 DOI: 10.1074/jbc.M212046200  1
2003 Sokal I, Hu G, Liang Y, Mao M, Wensel TG, Palczewski K. Identification of protein kinase C isozymes responsible for the phosphorylation of photoreceptor-specific RGS9-1 at Ser475. The Journal of Biological Chemistry. 278: 8316-25. PMID 12499365 DOI: 10.1074/jbc.M211782200  1
2002 Wensel TG. RGS9-1 phosphorylation and Ca2+. Advances in Experimental Medicine and Biology. 514: 125-9. PMID 12596919  1
2002 Hu G, Wensel TG. R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1. Proceedings of the National Academy of Sciences of the United States of America. 99: 9755-60. PMID 12119397 DOI: 10.1073/pnas.152094799  1
2002 Imanishi Y, Li N, Sokal I, Sowa ME, Lichtarge O, Wensel TG, Saperstein DA, Baehr W, Palczewski K. Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man. The European Journal of Neuroscience. 15: 63-78. PMID 11860507 DOI: 10.1046/j.0953-816x.2001.01835.x  1
2002 Sierra DA, Gilbert DJ, Householder D, Grishin NV, Yu K, Ukidwe P, Barker SA, He W, Wensel TG, Otero G, Brown G, Copeland NG, Jenkins NA, Wilkie TM. Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics. 79: 177-85. PMID 11829488 DOI: 10.1006/geno.2002.6693  1
2002 He W, Wensel TG. RGS function in visual signal transduction. Methods in Enzymology. 344: 724-40. PMID 11771423 DOI: 10.1016/S0076-6879(02)44751-9  1
2001 Shroyer NF, Lewis RA, Yatsenko AN, Wensel TG, Lupski JR. Cosegregation and functional analysis of mutant ABCR (ABCA4) alleles in families that manifest both Stargardt disease and age-related macular degeneration. Human Molecular Genetics. 10: 2671-8. PMID 11726554  1
2001 He W, Melia TJ, Cowan CW, Wensel TG. Dependence of RGS9-1 membrane attachment on its C-terminal tail. The Journal of Biological Chemistry. 276: 48961-6. PMID 11677233 DOI: 10.1074/jbc.M107428200  1
2001 Hu G, Jang GF, Cowan CW, Wensel TG, Palczewski K. Phosphorylation of RGS9-1 by an endogenous protein kinase in rod outer segments. The Journal of Biological Chemistry. 276: 22287-95. PMID 11292825 DOI: 10.1074/jbc.M011539200  1
2001 Lyubarsky AL, Naarendorp F, Zhang X, Wensel T, Simon MI, Pugh EN. RGS9-1 is required for normal inactivation of mouse cone phototransduction. Molecular Vision. 7: 71-8. PMID 11262419  1
2001 Slep KC, Kercher MA, He W, Cowan CW, Wensel TG, Sigler PB. Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Nature. 409: 1071-7. PMID 11234020 DOI: 10.1038/35059138  1
2001 Sowa ME, He W, Slep KC, Kercher MA, Lichtarge O, Wensel TG. Prediction and confirmation of a site critical for effector regulation of RGS domain activity. Nature Structural Biology. 8: 234-7. PMID 11224568 DOI: 10.1038/84974  1
2001 Cowan CW, He W, Wensel TG. RGS proteins: lessons from the RGS9 subfamily. Progress in Nucleic Acid Research and Molecular Biology. 65: 341-59. PMID 11008492  1
2000 Intody Z, Perkins BD, Wilson JH, Wensel TG. Blocking transcription of the human rhodopsin gene by triplex-mediated DNA photocrosslinking. Nucleic Acids Research. 28: 4283-90. PMID 11058128  1
2000 He W, Lu L, Zhang X, El-Hodiri HM, Chen CK, Slep KC, Simon MI, Jamrich M, Wensel TG. Modules in the photoreceptor RGS9-1.Gbeta 5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability. The Journal of Biological Chemistry. 275: 37093-100. PMID 10978345 DOI: 10.1074/jbc.M006982200  1
2000 He F, Seryshev AB, Cowan CW, Wensel TG. Multiple zinc binding sites in retinal rod cGMP phosphodiesterase, PDE6alpha beta. The Journal of Biological Chemistry. 275: 20572-7. PMID 10787404 DOI: 10.1074/jbc.M000440200  1
2000 Womack KB, Gordon SE, He F, Wensel TG, Lu CC, Hilgemann DW. Do phosphatidylinositides modulate vertebrate phototransduction? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2792-9. PMID 10751430  1
2000 Cowan CW, Wensel TG, Arshavsky VY. Enzymology of GTPase acceleration in phototransduction. Methods in Enzymology. 315: 524-38. PMID 10736724  1
2000 Sowa ME, He W, Wensel TG, Lichtarge O. A regulator of G protein signaling interaction surface linked to effector specificity. Proceedings of the National Academy of Sciences of the United States of America. 97: 1483-8. PMID 10677488 DOI: 10.1073/pnas.030409597  1
2000 Chen CK, Burns ME, He W, Wensel TG, Baylor DA, Simon MI. Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1. Nature. 403: 557-60. PMID 10676965 DOI: 10.1038/35000601  1
2000 Melia TJ, Malinski JA, He F, Wensel TG. Enhancement of phototransduction protein interactions by lipid surfaces. The Journal of Biological Chemistry. 275: 3535-42. PMID 10652348 DOI: 10.1074/jbc.275.5.3535  1
2000 Kovoor A, Chen CK, He W, Wensel TG, Simon MI, Lester HA. Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins. The Journal of Biological Chemistry. 275: 3397-402. PMID 10652332  0.72
2000 Kovoor A, Chen CK, He W, Wensel TG, Simon MI, Lester HA. Co-expression of Gβ5 enhances the function of two Gγ subunit-like domain-containing regulators of G protein signaling proteins Journal of Biological Chemistry. 275: 3397-3402. DOI: 10.1074/jbc.275.5.3397  1
1999 Melia TJ, Sowa ME, Schutze L, Wensel TG. Formation of helical protein assemblies of IgG and transducin on varied lipid tubules. Journal of Structural Biology. 128: 119-30. PMID 10600566 DOI: 10.1006/jsbi.1999.4151  1
1999 Zhang K, Howes KA, He W, Bronson JD, Pettenati MJ, Chen C, Palczewski K, Wensel TG, Baehr W. Structure, alternative splicing, and expression of the human RGS9 gene. Gene. 240: 23-34. PMID 10564809 DOI: 10.1016/S0378-1119(99)00393-5  1
1999 Perkins BD, Wensel TG, Vasquez KM, Wilson JH. Psoralen photo-cross-linking by triplex-forming oligonucleotides at multiple sites in the human rhodopsin gene. Biochemistry. 38: 12850-9. PMID 10504255 DOI: 10.1021/bi9902743  1
1999 DeMar JC, Rundle DR, Wensel TG, Anderson RE. Heterogeneous N-terminal acylation of retinal proteins. Progress in Lipid Research. 38: 49-90. PMID 10396602 DOI: 10.1016/S0163-7827(98)00020-4  1
1999 Rahman Z, Gold SJ, Potenza MN, Cowan CW, Ni YG, He W, Wensel TG, Nestler EJ. Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2016-26. PMID 10066255  1
1998 Perkins BD, Wilson JH, Wensel TG, Vasquez KM. Triplex targets in the human rhodopsin gene. Biochemistry. 37: 11315-22. PMID 9698379 DOI: 10.1021/bi980525s  1
1998 Cowan CW, Fariss RN, Sokal I, Palczewski K, Wensel TG. High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods. Proceedings of the National Academy of Sciences of the United States of America. 95: 5351-6. PMID 9560279 DOI: 10.1073/pnas.95.9.5351  1
1998 He W, Cowan CW, Wensel TG. RGS9, a GTPase accelerator for phototransduction. Neuron. 20: 95-102. PMID 9459445 DOI: 10.1016/S0896-6273(00)80437-7  1
1997 Melia TJ, Cowan CW, Angleson JK, Wensel TG. A comparison of the efficiency of G protein activation by ligand-free and light-activated forms of rhodopsin. Biophysical Journal. 73: 3182-91. PMID 9414230 DOI: 10.1016/S0006-3495(97)78344-9  1
1996 Vasquez KM, Wensel TG, Hogan ME, Wilson JH. High-efficiency triple-helix-mediated photo-cross-linking at a targeted site within a selectable mammalian gene. Biochemistry. 35: 10712-9. PMID 8718860 DOI: 10.1021/bi960881f  1
1996 Zera EM, Molloy DP, Angleson JK, Lamture JB, Wensel TG, Malinski JA. Low affinity interactions of GDPbetaS and ribose- or phosphoryl-substituted GTP analogues with the heterotrimeric G protein, transducin. The Journal of Biological Chemistry. 271: 12925-31. PMID 8662741  1
1996 Malinski JA, Zera EM, Angleson JK, Wensel TG. High affinity interactions of GTPgammaS with the heterotrimeric G protein, transducin. Evidence at high and low protein concentrations. The Journal of Biological Chemistry. 271: 12919-24. PMID 8662740  1
1996 DeMar JC, Wensel TG, Anderson RE. Biosynthesis of the unsaturated 14-carbon fatty acids found on the N termini of photoreceptor-specific proteins. The Journal of Biological Chemistry. 271: 5007-16. PMID 8617777 DOI: 10.1074/jbc.271.9.5007  1
1996 Cowan CW, Angleson JK, Wensel TG. Solubilization and partial purification of Gtα-GAP from rod outer segment membranes Investigative Ophthalmology and Visual Science. 37: S809.  1
1996 Melia TJ, Malinski JA, McGough A, Wensel TG. Ordered two-dimensional and helical arrays of transducin bound to lipid surfaces Investigative Ophthalmology and Visual Science. 37: S238.  1
1996 Wensel TG, Seryshev A, Cowan CW. Zinc and retinal cGMP phosphodiesterase Investigative Ophthalmology and Visual Science. 37: S239.  1
1996 Malinski JA, Melia TJ, Wensel TG. Stoichiometric activaton of retinal rod cGMP phosphodiesterase by Gtα-GTPγS Investigative Ophthalmology and Visual Science. 37: S809.  1
1995 Vasquez KM, Wensel TG, Hogan ME, Wilson JH. High-affinity triple helix formation by synthetic oligonucleotides at a site within a selectable mammalian gene. Biochemistry. 34: 7243-51. PMID 7766635  1
1995 Lamture JB, Wensel TG. Intensely luminescent immunoreactive conjugates of proteins and dipicolinate-based polymeric Tb (III) chelates. Bioconjugate Chemistry. 6: 88-92. PMID 7711110  1
1995 Wensel TG, Anglesson JK. More answers about cGMP-gated channels pose more questions Behavioral and Brain Sciences. 18: 492-493.  1
1995 Lamture JB, Zhou ZH, Kumar AS, Wensel TG. Luminescence properties of terbium(III) complexes with 4-substituted dipicolinic acid analogues Inorganic Chemistry. 34: 864-869.  1
1994 Angleson JK, Wensel TG. Enhancement of rod outer segment GTPase accelerating protein activity by the inhibitory subunit of cGMP phosphodiesterase. The Journal of Biological Chemistry. 269: 16290-6. PMID 8206935  1
1993 Angleson JK, Wensel TG. A GTPase-accelerating factor for transducin, distinct from its effector cGMP phosphodiesterase, in rod outer segment membranes. Neuron. 11: 939-49. PMID 8240815 DOI: 10.1016/0896-6273(93)90123-9  1
1993 Lamture JB, Wensel TG. A novel reagent for labelling macromolecules with intensely luminescent lanthanide complexes Tetrahedron Letters. 34: 4141-4144. DOI: 10.1016/S0040-4039(00)60512-9  1
1992 Yang Z, Wensel TG. N-myristoylation of the rod outer segment G protein, transducin, in cultured retinas. The Journal of Biological Chemistry. 267: 23197-201. PMID 1429667  1
1992 Yang Z, Wensel TG. Inorganic pyrophosphatase from bovine retinal rod outer segments. The Journal of Biological Chemistry. 267: 24634-40. PMID 1360011  1
1992 Yang Z, Wensel TG. Molecular cloning and functional expression of cDNA encoding a mammalian inorganic pyrophosphatase. The Journal of Biological Chemistry. 267: 24641-7. PMID 1339444  1
1992 Malinski JA, Wensel TG. Membrane stimulation of cGMP phosphodiesterase activation by transducin: comparison of phospholipid bilayers to rod outer segment membranes. Biochemistry. 31: 9502-12. PMID 1327116  1
1991 Keating SM, Wensel TG. Nanosecond fluorescence microscopy. Emission kinetics of fura-2 in single cells. Biophysical Journal. 59: 186-202. PMID 2015383 DOI: 10.1016/S0006-3495(91)82210-X  1
1991 Ramdas L, Disher RM, Wensel TG. Nucleotide exchange and cGMP phosphodiesterase activation by pertussis toxin inactivated transducin. Biochemistry. 30: 11637-45. PMID 1661143  1
1990 Northrup SH, Wensel TG, Meares CF, Wendoloski JJ, Matthew JB. Electrostatic field around cytochrome c: theory and energy transfer experiment. Proceedings of the National Academy of Sciences of the United States of America. 87: 9503-7. PMID 2174564  1
1990 Wensel TG, Stryer L. Activation mechanism of retinal rod cyclic GMP phosphodiesterase probed by fluorescein-labeled inhibitory subunit. Biochemistry. 29: 2155-61. PMID 2158346  1
1989 Wensel TG, Meares CF. Study of biological macromolecules by diffusion-enhanced lanthanide energy transfer Journal of the Less-Common Metals. 149: 143-160. DOI: 10.1016/0022-5088(89)90481-5  1
1988 Dangl JL, Wensel TG, Morrison SL, Stryer L, Herzenberg LA, Oi VT. Segmental flexibility and complement fixation of genetically engineered chimeric human, rabbit and mouse antibodies. The Embo Journal. 7: 1989-94. PMID 3138110  1
1988 Schneider WP, Wensel TG, Stryer L, Oi VT. Genetically engineered immunoglobulins reveal structural features controlling segmental flexibility. Proceedings of the National Academy of Sciences of the United States of America. 85: 2509-13. PMID 3128789  1
1986 Wensel TG, Meares CF, Vlachy V, Matthew JB. Distribution of ions around DNA, probed by energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 83: 3267-71. PMID 3458180  1
1986 Haseman MK, Goodwin DA, Meares CF, Kaminski MS, Wensel TG, McCall MJ, Levy R. Metabolizable 111In chelate conjugated anti-idiotype monoclonal antibody for radioimmunodetection of lymphoma in mice. European Journal of Nuclear Medicine. 12: 455-60. PMID 3102237 DOI: 10.1007/BF00254750  1
1986 Wensel TG, Stryer L. Reciprocal control of retinal rod cyclic GMP phosphodiesterase by its gamma subunit and transducin. Proteins. 1: 90-9. PMID 2835761 DOI: 10.1002/prot.340010114  1
1985 Wensel TG, Chang CH, Meares CF. Diffusion-enhanced lanthanide energy-transfer study of DNA-bound cobalt(III) bleomycins: comparisons of accessibility and electrostatic potential with DNA complexes of ethidium and acridine orange. Biochemistry. 24: 3060-9. PMID 2410019  1
1984 Meares CF, Wensel TG. Metal chelates as probes of biological systems Accounts of Chemical Research. 17: 202-209.  1
1983 Wensel TG, Meares CF. Electrostatic properties of myoglobin probed by diffusion-enhanced energy transfer Biochemistry. 22: 6247-6254.  1
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