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Johanna Nilsson - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 
Area:
Ion channels
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Paucar M, Ågren R, Li T, Lissmats S, Bergendal Å, Weinberg J, Nilsson D, Savichetva I, Sahlholm K, Nilsson J, Svenningsson P. V374A KCND3 Pathogenic Variant Associated With Paroxysmal Ataxia Exacerbations. Neurology. Genetics. 7: e546. PMID 33575485 DOI: 10.1212/NXG.0000000000000546  0.698
2020 Ågren R, Zeberg H, Maciej Stępniewski T, Free RB, Reilly SW, Luedtke RR, Århem P, Ciruela F, Sibley DR, Mach RH, Selent J, Nilsson J, Sahlholm K. A ligand with two modes of interaction with the dopamine D2 receptor - An induced-fit mechanism of insurmountable antagonism. Acs Chemical Neuroscience. PMID 32865974 DOI: 10.1021/Acschemneuro.0C00477  0.798
2019 Ågren R, Nilsson J, Århem P. Closed and open state dependent block of potassium channels cause opposing effects on excitability - a computational approach. Scientific Reports. 9: 8175. PMID 31160624 DOI: 10.1038/S41598-019-44564-X  0.68
2018 Ågren R, Århem P, Nilsson J, Sahlholm K. The beta-arrestin-biased dopamine D2 receptor ligand, UNC9994, is a partial agonist at G-protein-mediated potassium channel activation. The International Journal of Neuropsychopharmacology. PMID 29986044 DOI: 10.1093/Ijnp/Pyy059  0.786
2018 Zeberg H, Nilsson J, Århem P. The Importance of the Dissociation Rate in Ion Channel Blocking. Frontiers in Cellular Neuroscience. 12: 33. PMID 29479308 DOI: 10.3389/Fncel.2018.00033  0.784
2018 Ågren R, Sahlholm K, Nilsson J, Århem P. Point mutation of a conserved aspartate, D69, in the muscarinic M2 receptor does not modify voltage-sensitive agonist potency. Biochemical and Biophysical Research Communications. PMID 29305262 DOI: 10.1016/J.Bbrc.2018.01.005  0.799
2016 Sahlholm K, Zeberg H, Nilsson J, Ögren SO, Fuxe K, Århem P. The fast-off hypothesis revisited: A functional kinetic study of antipsychotic antagonism of the dopamine D2 receptor. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26811292 DOI: 10.1016/J.Euroneuro.2016.01.001  0.789
2015 Lyu C, Mulder J, Barde S, Sahlholm K, Zeberg H, Nilsson J, Århem P, Hökfelt T, Fried K, Shi TJ. G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy. Molecular Pain. 11: 44. PMID 26199148 DOI: 10.1186/S12990-015-0044-Z  0.769
2014 Sahlholm K, Marcellino D, Nilsson J, Ögren SO, Fuxe K, Ã…rhem P. Typical and atypical antipsychotics do not differ markedly in their reversibility of antagonism of the dopamine D2 receptor. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 149-55. PMID 24074141 DOI: 10.1017/S1461145713000801  0.78
2014 Sahlholm K, Zeberg H, Marcellino D, Nilsson J, Ogren S, Fuxe K, Arhem P. P.3.c.010 The fast-off hypothesis revisited: on-rates and reversibility of antipsychotic antagonism at the D2 receptor European Neuropsychopharmacology. 24: S520. DOI: 10.1016/S0924-977X(14)70833-8  0.772
2013 Shi TJ, Zhang MD, Zeberg H, Nilsson J, Grünler J, Liu SX, Xiang Q, Persson J, Fried KJ, Catrina SB, Watanabe M, Arhem P, Brismar K, Hökfelt TG. Coenzyme Q10 prevents peripheral neuropathy and attenuates neuron loss in the db-/db- mouse, a type 2 diabetes model. Proceedings of the National Academy of Sciences of the United States of America. 110: 690-5. PMID 23267110 DOI: 10.1073/Pnas.1220794110  0.703
2013 Nilsson J, Zeberg H, Madeja M, Arhem P. Local Anesthetics on Kv Channels - Closed State Binding of Bupivacaine? Biophysical Journal. 104: 126a. DOI: 10.1016/J.Bpj.2012.11.726  0.797
2013 Sahlholm K, Frisk S, Nilsson J, Marcellino D, Fuxe K, Ove Ögren S, Århem P. Novel Aspects of the Reversibility of the Antagonism at the Dopamine D2 Receptor by Antipsychotics Biophysical Journal. 104: 26a. DOI: 10.1016/J.Bpj.2012.11.183  0.787
2012 Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. Voltage sensitivities and deactivation kinetics of histamine H₃ and Hâ‚„ receptors. Biochimica Et Biophysica Acta. 1818: 3081-9. PMID 22885137 DOI: 10.1016/J.Bbamem.2012.07.027  0.785
2012 Sahlholm K, Frisk S, Marcellino D, Nilsson J, Fuxe K, Århem P. P.1.030 Antagonist dissociation from dopamine D2 receptors: studies using a time-resolved ion channel activation assay European Neuropsychopharmacology. 22: S29. DOI: 10.1016/S0924-977X(12)70031-7  0.795
2012 Nilsson J, Kempka M, Arhem P. The Action of the Neuroprotective Compound Riluzole on Kv Channels Biophysical Journal. 102: 134a. DOI: 10.1016/J.Bpj.2011.11.742  0.69
2012 Sahlholm K, Frisk S, Nilsson J, Marcellino D, Fuxe Peter Århem K. Dopamine D2 Receptor Antagonist Unbinding Rates Investigated using a Time-Resolved Ion Channel Activation Assay Biophysical Journal. 102: 517a. DOI: 10.1016/J.Bpj.2011.11.2829  0.744
2010 Marcellino D, Navarro G, Sahlholm K, Nilsson J, Agnati LF, Canela EI, Lluís C, Ã…rhem P, Franco R, Fuxe K. Cocaine produces D2R-mediated conformational changes in the adenosine A(2A)R-dopamine D2R heteromer. Biochemical and Biophysical Research Communications. 394: 988-92. PMID 20307491 DOI: 10.1016/J.Bbrc.2010.03.104  0.734
2010 Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Århem P. Agonist-Specific Effects of TM V Serine Mutations on Dopamine D2S Receptor Voltage-Sensitivity Biophysical Journal. 98: 290a. DOI: 10.1016/J.Bpj.2009.12.1581  0.796
2010 Nilsson J, Madeja M, Sahlholm K, Arhem P. Kv Channel Modulation: Closed State Block of Benzocaine But Not of Bupivacaine Biophysical Journal. 98: 213a. DOI: 10.1016/J.Bpj.2009.12.1149  0.797
2009 Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Århem P. Differential Voltage-sensitivities Of Agonists At The Dopamine D2S Receptor Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1986  0.749
2008 Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Arhem P. Voltage-sensitivity at the human dopamine D2S receptor is agonist-specific. Biochemical and Biophysical Research Communications. 377: 1216-21. PMID 18983826 DOI: 10.1016/J.Bbrc.2008.10.117  0.8
2008 Nilsson J, Madeja M, Elinder F, Arhem P. Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics. Biophysical Journal. 95: 5138-52. PMID 18790854 DOI: 10.1529/Biophysj.108.130518  0.779
2008 Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Arhem P. Differential voltage-sensitivity of D2-like dopamine receptors. Biochemical and Biophysical Research Communications. 374: 496-501. PMID 18652803 DOI: 10.1016/J.Bbrc.2008.07.052  0.788
2008 Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. Electrophysiology-based analysis of human histamine H(4) receptor pharmacology using GIRK channel coupling in Xenopus oocytes. European Journal of Pharmacology. 591: 52-8. PMID 18582456 DOI: 10.1016/J.Ejphar.2008.06.029  0.784
2008 Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. Voltage-dependence of the human dopamine D2 receptor. Synapse (New York, N.Y.). 62: 476-80. PMID 18361445 DOI: 10.1002/Syn.20509  0.801
2008 Klement G, Nilsson J, Arhem P, Elinder F. A tyrosine substitution in the cavity wall of a k channel induces an inverted inactivation. Biophysical Journal. 94: 3014-22. PMID 18192362 DOI: 10.1529/Biophysj.107.119842  0.806
2008 Århem P, Sahlholm K, Nilsson J. Mechanisms of Anaesthesia: A Role for Voltage-Gated K Channels? Anaesthesia Science. 117-127. DOI: 10.1002/9780470755297.ch9  0.767
2007 Elinder F, Nilsson J, Arhem P. On the opening of voltage-gated ion channels. Physiology & Behavior. 92: 1-7. PMID 17585963 DOI: 10.1016/J.Physbeh.2007.05.058  0.771
2007 Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes. European Journal of Pharmacology. 567: 206-10. PMID 17537431 DOI: 10.1016/J.Ejphar.2007.04.032  0.784
2007 Bränström R, Leibiger IB, Leibiger B, Klement G, Nilsson J, Arhem P, Aspinwall CA, Corkey BE, Larsson O, Berggren PO. Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif. Diabetologia. 50: 1670-7. PMID 17522836 DOI: 10.1007/S00125-007-0697-X  0.749
2005 Persson AS, Klement G, Almgren M, Sahlholm K, Nilsson J, Petersson S, Arhem P, Schalling M, Lavebratt C. A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction. Bmc Neuroscience. 6: 65. PMID 16305740 DOI: 10.1186/1471-2202-6-65  0.763
2003 Petersson S, Persson AS, Johansen JE, Ingvar M, Nilsson J, Klement G, Arhem P, Schalling M, Lavebratt C. Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly. The European Journal of Neuroscience. 18: 3231-40. PMID 14686897 DOI: 10.1111/J.1460-9568.2003.03044.X  0.746
2003 Luzhkov VB, Nilsson J, Arhem P, Aqvist J. Computational modelling of the open-state Kv 1.5 ion channel block by bupivacaine. Biochimica Et Biophysica Acta. 1652: 35-51. PMID 14580995 DOI: 10.1016/J.Bbapap.2003.08.006  0.68
2003 Arhem P, Klement G, Nilsson J. Mechanisms of anesthesia: towards integrating network, cellular, and molecular level modeling. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: S40-7. PMID 12827143 DOI: 10.1038/Sj.Npp.1300142  0.761
2003 Nilsson J, Madeja M, Arhem P. Local anesthetic block of Kv channels: role of the S6 helix and the S5-S6 linker for bupivacaine action. Molecular Pharmacology. 63: 1417-29. PMID 12761353 DOI: 10.1124/Mol.63.6.1417  0.692
1998 Nilsson J, Elinder F, Arhem P. Mechanisms of bupivacaine action on Na+ and K+ channels in myelinated axons of Xenopus laevis. European Journal of Pharmacology. 360: 21-9. PMID 9845268 DOI: 10.1016/S0014-2999(98)00631-1  0.757
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