John W. Olney, MD - Publications

Affiliations: 
Psychiatry Washington University, Saint Louis, St. Louis, MO 
Area:
excitotoxicity

209 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Noguchi KK, Johnson SA, Manzella FM, Masuoka KL, Williams SL, Martin LD, Dissen GA, Ikonomidou C, Schenning KJ, Olney JW, Brambrink AM. Caffeine Augments Anesthesia Neurotoxicity in the Fetal Macaque Brain. Scientific Reports. 8: 5302. PMID 29593226 DOI: 10.1038/S41598-018-23560-7  0.392
2017 Noguchi KK, Johnson SA, Dissen GA, Martin LD, Manzella FM, Schenning KJ, Olney JW, Brambrink AM. Isoflurane exposure for three hours triggers apoptotic cell death in neonatal macaque brain. British Journal of Anaesthesia. 119: 524-531. PMID 28969320 DOI: 10.1093/Bja/Aex123  0.356
2016 Noguchi KK, Johnson SA, Kristich LE, Martin LD, Dissen GA, Olsen EA, Olney JW, Brambrink AM. Lithium Protects Against Anaesthesia Neurotoxicity In The Infant Primate Brain. Scientific Reports. 6: 22427. PMID 26951756 DOI: 10.1038/Srep22427  0.353
2014 Olney JW. Focus on apoptosis to decipher how alcohol and many other drugs disrupt brain development. Frontiers in Pediatrics. 2: 81. PMID 25136546 DOI: 10.3389/Fped.2014.00081  0.328
2014 Creeley CE, Dikranian KT, Dissen GA, Back SA, Olney JW, Brambrink AM. Isoflurane-induced apoptosis of neurons and oligodendrocytes in the fetal rhesus macaque brain. Anesthesiology. 120: 626-38. PMID 24158051 DOI: 10.1097/Aln.0000000000000037  0.398
2013 Yuede CM, Olney JW, Creeley CE. Developmental neurotoxicity of alcohol and anesthetic drugs is augmented by co-exposure to caffeine. Brain Sciences. 3: 1128-52. PMID 24734165 DOI: 10.3390/Brainsci3031128  0.316
2013 Creeley CE, Olney JW. Drug-Induced Apoptosis: Mechanism by which Alcohol and Many Other Drugs Can Disrupt Brain Development. Brain Sciences. 3: 1153-81. PMID 24587895 DOI: 10.3390/Brainsci3031153  0.357
2013 Creeley CE, Dikranian KT, Johnson SA, Farber NB, Olney JW. Alcohol-induced apoptosis of oligodendrocytes in the fetal macaque brain. Acta Neuropathologica Communications. 1: 23. PMID 24252271 DOI: 10.1186/2051-5960-1-23  0.366
2013 Creeley C, Dikranian K, Dissen G, Martin L, Olney J, Brambrink A. Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain British Journal of Anaesthesia. 110: i29-i38. PMID 23722059 DOI: 10.1093/Bja/Aet173  0.405
2012 Brambrink AM, Back SA, Riddle A, Gong X, Moravec MD, Dissen GA, Creeley CE, Dikranian KT, Olney JW. Isoflurane-induced apoptosis of oligodendrocytes in the neonatal primate brain. Annals of Neurology. 72: 525-35. PMID 23109147 DOI: 10.1002/Ana.23652  0.396
2010 Yuede CM, Wozniak DF, Creeley CE, Taylor GT, Olney JW, Farber NB. Behavioral consequences of NMDA antagonist-induced neuroapoptosis in the infant mouse brain. Plos One. 5: e11374. PMID 20613880 DOI: 10.1371/Journal.Pone.0011374  0.591
2010 Farber NB, Creeley CE, Olney JW. Alcohol-induced neuroapoptosis in the fetal macaque brain. Neurobiology of Disease. 40: 200-6. PMID 20580929 DOI: 10.1016/J.Nbd.2010.05.025  0.325
2010 Christensen HM, Dikranian K, Li A, Baysac KC, Walls KC, Olney JW, Roth KA, Harris DA. A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death. The American Journal of Pathology. 176: 2695-706. PMID 20472884 DOI: 10.2353/Ajpath.2010.091007  0.358
2010 Brambrink AM, Evers AS, Avidan MS, Farber NB, Smith DJ, Zhang X, Dissen GA, Creeley CE, Olney JW. Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain. Anesthesiology. 112: 834-41. PMID 20234312 DOI: 10.1097/Aln.0B013E3181D049Cd  0.376
2010 Creeley CE, Olney JW. The young: neuroapoptosis induced by anesthetics and what to do about it. Anesthesia and Analgesia. 110: 442-8. PMID 19955510 DOI: 10.1213/Ane.0B013E3181C6B9Ca  0.364
2009 Straiko MM, Young C, Cattano D, Creeley CE, Wang H, Smith DJ, Johnson SA, Li ES, Olney JW. Lithium protects against anesthesia-induced developmental neuroapoptosis. Anesthesiology. 110: 862-8. PMID 19293695 DOI: 10.1097/Aln.0B013E31819B5Eab  0.326
2009 Dribben WH, Creeley CE, Wang HH, Smith DJ, Farber NB, Olney JW. High dose magnesium sulfate exposure induces apoptotic cell death in the developing neonatal mouse brain. Neonatology. 96: 23-32. PMID 19204407 DOI: 10.1159/000201327  0.412
2009 Hanslick JL, Lau K, Noguchi KK, Olney JW, Zorumski CF, Mennerick S, Farber NB. Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system. Neurobiology of Disease. 34: 1-10. PMID 19100327 DOI: 10.1016/J.Nbd.2008.11.006  0.356
2009 Conti AC, Young C, Olney JW, Muglia LJ. Adenylyl cyclases types 1 and 8 promote pro-survival pathways after ethanol exposure in the neonatal brain. Neurobiology of Disease. 33: 111-8. PMID 18992344 DOI: 10.1016/J.Nbd.2008.09.022  0.322
2008 Noguchi KK, Walls KC, Wozniak DF, Olney JW, Roth KA, Farber NB. Acute neonatal glucocorticoid exposure produces selective and rapid cerebellar neural progenitor cell apoptotic death. Cell Death and Differentiation. 15: 1582-92. PMID 18600230 DOI: 10.1038/Cdd.2008.97  0.561
2008 Young C, Straiko MM, Johnson SA, Creeley C, Olney JW. Ethanol causes and lithium prevents neuroapoptosis and suppression of pERK in the infant mouse brain. Neurobiology of Disease. 31: 355-60. PMID 18595723 DOI: 10.1016/J.Nbd.2008.05.009  0.325
2008 Cattano D, Williamson P, Fukui K, Avidan M, Evers AS, Olney JW, Young C. Potential of xenon to induce or to protect against neuroapoptosis in the developing mouse brain. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthã©Sie. 55: 429-36. PMID 18591700 DOI: 10.1007/Bf03016309  0.408
2008 Cattano D, Young C, Straiko MM, Olney JW. Subanesthetic doses of propofol induce neuroapoptosis in the infant mouse brain. Anesthesia and Analgesia. 106: 1712-4. PMID 18499599 DOI: 10.1213/Ane.0B013E318172Ba0A  0.403
2008 Jevtovic-Todorovic V, Olney JW. PRO: Anesthesia-induced developmental neuroapoptosis: status of the evidence. Anesthesia and Analgesia. 106: 1659-63. PMID 18499594 DOI: 10.1213/Ane.0B013E3181731Ff2  0.3
2008 Johnson SA, Young C, Olney JW. Isoflurane-induced neuroapoptosis in the developing brain of nonhypoglycemic mice. Journal of Neurosurgical Anesthesiology. 20: 21-8. PMID 18157021 DOI: 10.1097/Ana.0B013E3181271850  0.392
2008 Creeley CE, Wozniak DF, Nardi A, Farber NB, Olney JW. Donepezil markedly potentiates memantine neurotoxicity in the adult rat brain. Neurobiology of Aging. 29: 153-67. PMID 17112636 DOI: 10.1016/J.Neurobiolaging.2006.10.020  0.619
2007 Shacka JJ, Klocke BJ, Young C, Shibata M, Olney JW, Uchiyama Y, Saftig P, Roth KA. Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2081-90. PMID 17314303 DOI: 10.1523/Jneurosci.5577-06.2007  0.344
2006 Bayly PV, Dikranian KT, Black EE, Young C, Qin YQ, Labruyere J, Olney JW. Spatiotemporal evolution of apoptotic neurodegeneration following traumatic injury to the developing rat brain. Brain Research. 1107: 70-81. PMID 16822489 DOI: 10.1016/J.Brainres.2006.05.102  0.338
2006 Creeley C, Wozniak DF, Labruyere J, Taylor GT, Olney JW. Low doses of memantine disrupt memory in adult rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3923-32. PMID 16611808 DOI: 10.1523/Jneurosci.4883-05.2006  0.581
2006 Young C, Olney JW. Neuroapoptosis in the infant mouse brain triggered by a transient small increase in blood alcohol concentration. Neurobiology of Disease. 22: 548-54. PMID 16459096 DOI: 10.1016/J.Nbd.2005.12.015  0.342
2005 Young C, Jevtovic-Todorovic V, Qin YQ, Tenkova T, Wang H, Labruyere J, Olney JW. Potential of ketamine and midazolam, individually or in combination, to induce apoptotic neurodegeneration in the infant mouse brain. British Journal of Pharmacology. 146: 189-97. PMID 15997239 DOI: 10.1038/Sj.Bjp.0706301  0.38
2005 Young C, Roth KA, Klocke BJ, West T, Holtzman DM, Labruyere J, Qin YQ, Dikranian K, Olney JW. Role of caspase-3 in ethanol-induced developmental neurodegeneration. Neurobiology of Disease. 20: 608-14. PMID 15927478 DOI: 10.1016/J.Nbd.2005.04.014  0.51
2005 Soriano SG, Anand KJS, Rovnaghi CR, Hickey PR, Olney JW, Young C, Wozniak DF, Ikonomidou C, Jevtovic-Todorovic V. Of mice and men: Should we extrapolate rodent experimental data to the care of human neonates? [3] (multiple letters) Anesthesiology. 102: 866-869. PMID 15791124 DOI: 10.1097/00000542-200504000-00030  0.417
2005 Dikranian K, Qin YQ, Labruyere J, Nemmers B, Olney JW. Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures. Brain Research. Developmental Brain Research. 155: 1-13. PMID 15763270 DOI: 10.1016/J.Devbrainres.2004.11.005  0.412
2005 Maas JW, Indacochea RA, Muglia LM, Tran TT, Vogt SK, West T, Benz A, Shute AA, Holtzman DM, Mennerick S, Olney JW, Muglia LJ. Calcium-stimulated adenylyl cyclases modulate ethanol-induced neurodegeneration in the neonatal brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2376-85. PMID 15745964 DOI: 10.1523/Jneurosci.4940-04.2005  0.533
2004 Wozniak DF, Hartman RE, Boyle MP, Vogt SK, Brooks AR, Tenkova T, Young C, Olney JW, Muglia LJ. Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults. Neurobiology of Disease. 17: 403-14. PMID 15571976 DOI: 10.1016/J.Nbd.2004.08.006  0.721
2004 Izumi Y, Matsukawa M, Benz AM, Izumi M, Ishikawa M, Olney JW, Zorumski CF. Role of ammonia in reversal of glutamate-mediated Müller cell swelling in the rat retina. Glia. 48: 44-50. PMID 15326614 DOI: 10.1002/Glia.20052  0.399
2004 Creeley CE, Wozniak DF, Bayly PV, Olney JW, Lewis LM. Multiple episodes of mild traumatic brain injury result in impaired cognitive performance in mice. Academic Emergency Medicine : Official Journal of the Society For Academic Emergency Medicine. 11: 809-19. PMID 15289185 DOI: 10.1197/J.Aem.2004.03.006  0.537
2004 Olney JW, Young C, Wozniak DF, Ikonomidou C, Jevtovic-Todorovic V. Anesthesia-induced developmental neuroapoptosis. Does it happen in humans? Anesthesiology. 101: 273-5. PMID 15277906 DOI: 10.1097/00000542-200408000-00004  0.507
2004 Olney JW. Fetal alcohol syndrome at the cellular level. Addiction Biology. 9: 137-49; discussion 1. PMID 15223539 DOI: 10.1080/13556210410001717006  0.41
2004 Sun L, Chiu D, Kowal D, Simon R, Smeyne M, Zukin RS, Olney J, Baudy R, Lin S. Characterization of two novel N-methyl-D-aspartate antagonists: EAA-090 (2-[8,9-dioxo-2,6-diazabicyclo [5.2.0]non-1(7)-en2-yl]ethylphosphonic acid) and EAB-318 (R-alpha-amino-5-chloro-1-(phosphonomethyl)-1H-benzimidazole-2-propanoic acid hydrochloride). The Journal of Pharmacology and Experimental Therapeutics. 310: 563-70. PMID 15075380 DOI: 10.1124/jpet.104.066092  0.314
2004 Young C, Tenkova T, Dikranian K, Olney JW. Excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemia. Current Molecular Medicine. 4: 77-85. PMID 15032706 DOI: 10.2174/1566524043479158  0.36
2004 Olney JW, Young C, Wozniak DF, Jevtovic-Todorovic V, Ikonomidou C. Do pediatric drugs cause developing neurons to commit suicide? Trends in Pharmacological Sciences. 25: 135-9. PMID 15019268 DOI: 10.1016/J.Tips.2004.01.002  0.567
2004 Lewis L, Bayly P, Black E, Creeley C, Wozniak D, Krikor D, Olney J. Apolipoprotein-deficient mice are more susceptible to mild traumatic brain injury than are wild-type mice Annals of Emergency Medicine. 44: S121-S122. DOI: 10.1016/J.Annemergmed.2004.08.021  0.545
2003 Jevtovic-Todorovic V, Beals J, Benshoff N, Olney JW. Prolonged exposure to inhalational anesthetic nitrous oxide kills neurons in adult rat brain. Neuroscience. 122: 609-16. PMID 14622904 DOI: 10.1016/J.Neuroscience.2003.07.012  0.437
2003 Young C, Klocke BJ, Tenkova T, Choi J, Labruyere J, Qin YQ, Holtzman DM, Roth KA, Olney JW. Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain. Cell Death and Differentiation. 10: 1148-55. PMID 14502238 DOI: 10.1038/sj.cdd.4401277  0.408
2003 Izumi Y, Hammerman SB, Kirby CO, Benz AM, Olney JW, Zorumski CF. Involvement of glutamate in ischemic neurodegeneration in isolated retina. Visual Neuroscience. 20: 97-107. PMID 12916732 DOI: 10.1017/S0952523803202017  0.391
2003 Tenkova T, Young C, Dikranian K, Labruyere J, Olney JW. Ethanol-induced apoptosis in the developing visual system during synaptogenesis. Investigative Ophthalmology & Visual Science. 44: 2809-17. PMID 12824217 DOI: 10.1167/Iovs.02-0982  0.35
2003 Dribben WH, Nemmers BM, Nardi AR, Taylor GT, Olney JW, Farber NB. Chronic but not acute estradiol treatment protects against the neurodegenerative effects of N-methyl-D-aspartate receptor antagonists Endocrine. 21: 53-58. PMID 12777703 DOI: 10.1385/Endo:21:1:53  0.413
2003 Jevtovic-Todorovic V, Meyenburg AP, Olney JW, Wozniak DF. Anti-parkinsonian agents procyclidine and ethopropazine alleviate thermal hyperalgesia in neuropathic rats. Neuropharmacology. 44: 739-48. PMID 12681372 DOI: 10.1016/S0028-3908(03)00069-8  0.537
2003 Jevtovic-Todorovic V, Hartman RE, Izumi Y, Benshoff ND, Dikranian K, Zorumski CF, Olney JW, Wozniak DF. Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 876-82. PMID 12574416 DOI: 10.1097/00008506-200307000-00029  0.739
2003 Brendza RP, O'Brien C, Simmons K, McKeel DW, Bales KR, Paul SM, Olney JW, Sanes JR, Holtzman DM. PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures. The Journal of Comparative Neurology. 456: 375-83. PMID 12532409 DOI: 10.1002/Cne.10536  0.442
2002 Olney JW, Wozniak DF, Jevtovic-Todorovic V, Farber NB, Bittigau P, Ikonomidou C. Glutamate and GABA receptor dysfunction in the fetal alcohol syndrome. Neurotoxicity Research. 4: 315-25. PMID 12829421 DOI: 10.1080/1029842021000010875  0.634
2002 Olney JW. New insights and new issues in developmental neurotoxicology. Neurotoxicology. 23: 659-68. PMID 12520755 DOI: 10.1016/S0161-813X(01)00092-4  0.498
2002 Bittigau P, Sifringer M, Genz K, Reith E, Pospischil D, Govindarajalu S, Dzietko M, Pesditschek S, Mai I, Dikranian K, Olney JW, Ikonomidou C. Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. Proceedings of the National Academy of Sciences of the United States of America. 99: 15089-94. PMID 12417760 DOI: 10.1073/Pnas.222550499  0.339
2002 Olney JW, Wozniak DF, Jevtovic-Todorovic V, Farber NB, Bittigau P, Ikonomidou C. Drug-induced apoptotic neurodegeneration in the developing brain. Brain Pathology (Zurich, Switzerland). 12: 488-98. PMID 12408236 DOI: 10.1111/J.1750-3639.2002.Tb00467.X  0.652
2002 Izumi Y, Shimamoto K, Benz AM, Hammerman SB, Olney JW, Zorumski CF. Glutamate transporters and retinal excitotoxicity. Glia. 39: 58-68. PMID 12112376 DOI: 10.1002/Glia.10082  0.377
2002 Olney JW, Wozniak DF, Farber NB, Jevtovic-Todorovic V, Bittigau P, Ikonomidou C. The enigma of fetal alcohol neurotoxicity. Annals of Medicine. 34: 109-19. PMID 12108574 DOI: 10.1080/07853890252953509  0.621
2002 Olney JW, Tenkova T, Dikranian K, Muglia LJ, Jermakowicz WJ, D'Sa C, Roth KA. Ethanol-induced caspase-3 activation in the in vivo developing mouse brain. Neurobiology of Disease. 9: 205-19. PMID 11895372 DOI: 10.1006/Nbdi.2001.0475  0.448
2002 Olney JW, Tenkova T, Dikranian K, Qin YQ, Labruyere J, Ikonomidou C. Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain. Brain Research. Developmental Brain Research. 133: 115-26. PMID 11882342 DOI: 10.1016/S0165-3806(02)00279-1  0.379
2001 Olney JW, Wozniak DF, Jevtovic-Todorovic V, Ikonomidou C. Glutamate signaling and the fetal alcohol syndrome. Mental Retardation and Developmental Disabilities Research Reviews. 7: 267-75. PMID 11754521 DOI: 10.1002/Mrdd.1037  0.624
2001 Jevtovic-Todorovic V, Wozniak DF, Powell S, Olney JW. Propofol and sodium thiopental protect against MK-801-induced neuronal necrosis in the posterior cingulate/retrosplenial cortex. Brain Research. 913: 185-9. PMID 11549385 DOI: 10.1016/S0006-8993(01)02800-1  0.639
2001 Hartman RE, Wozniak DF, Nardi A, Olney JW, Sartorius L, Holtzman DM. Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology. Experimental Neurology. 170: 326-44. PMID 11476599 DOI: 10.1006/Exnr.2001.7715  0.705
2001 Ikonomidou C, Bittigau P, Koch C, Genz K, Hoerster F, Felderhoff-Mueser U, Tenkova T, Dikranian K, Olney JW. Neurotransmitters and apoptosis in the developing brain. Biochemical Pharmacology. 62: 401-5. PMID 11448448 DOI: 10.1016/S0006-2952(01)00696-7  0.449
2001 Dikranian K, Ishimaru MJ, Tenkova T, Labruyere J, Qin YQ, Ikonomidou C, Olney JW. Apoptosis in the in vivo mammalian forebrain. Neurobiology of Disease. 8: 359-79. PMID 11447994 DOI: 10.1006/Nbdi.2001.0411  0.387
2001 Cavalheiro EA, Olney JW. Glutamate antagonists: deadly liaisons with cancer. Proceedings of the National Academy of Sciences of the United States of America. 98: 5947-8. PMID 11371628 DOI: 10.1073/Pnas.121179198  0.446
2001 Jevtovic-Todorovic V, Wozniak DF, Benshoff ND, Olney JW. A comparative evaluation of the neurotoxic properties of ketamine and nitrous oxide. Brain Research. 895: 264-7. PMID 11259788 DOI: 10.1016/S0006-8993(01)02079-0  0.557
2000 Newcomer JW, Farber NB, Olney JW. NMDA receptor function, memory, and brain aging. Dialogues in Clinical Neuroscience. 2: 219-32. PMID 22034391  0.33
2000 Olney JW, Ishimaru MJ, Bittigau P, Ikonomidou C. Ethanol-induced apoptotic neurodegeneration in the developing brain. Apoptosis : An International Journal On Programmed Cell Death. 5: 515-21. PMID 11303910 DOI: 10.1023/A:1009685428847  0.421
2000 Jevtovic-Todorovic V, Benshoff N, Olney JW. Ketamine potentiates cerebrocortical damage induced by the common anaesthetic agent nitrous oxide in adult rats. British Journal of Pharmacology. 130: 1692-8. PMID 10928976 DOI: 10.1038/Sj.Bjp.0703479  0.386
2000 Olney JW, Farber NB, Wozniak DF, Jevtovic-Todorovic V, Ikonomidou C. Environmental agents that have the potential to trigger massive apoptotic neurodegeneration in the developing brain. Environmental Health Perspectives. 108: 383-8. PMID 10852832 DOI: 10.1289/Ehp.00108S3383  0.615
2000 Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ, Mackey B, Olney J, McKeel D, Wozniak D, Paul SM. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 97: 2892-7. PMID 10694577 DOI: 10.1073/Pnas.050004797  0.572
2000 Ikonomidou C, Bittigau P, Ishimaru MJ, Wozniak DF, Koch C, Genz K, Price MT, Stefovska V, Hörster F, Tenkova T, Dikranian K, Olney JW. Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome. Science (New York, N.Y.). 287: 1056-60. PMID 10669420 DOI: 10.1126/Science.287.5455.1056  0.607
1999 Chen Q, Moulder K, Tenkova T, Hardy K, Olney JW, Romano C. Excitotoxic cell death dependent on inhibitory receptor activation. Experimental Neurology. 160: 215-25. PMID 10630206 DOI: 10.1006/Exnr.1999.7179  0.356
1999 Olney JW, Newcomer JW, Farber NB. NMDA receptor hypofunction model of schizophrenia. Journal of Psychiatric Research. 33: 523-33. PMID 10628529 DOI: 10.1016/S0022-3956(99)00029-1  0.373
1999 Kim SH, Price MT, Olney JW, Farber NB. Excessive cerebrocortical release of acetylcholine induced by NMDA antagonists is reduced by GABAergic and alpha2-adrenergic agonists. Molecular Psychiatry. 4: 344-52. PMID 10483051 DOI: 10.1038/Sj.Mp.4000529  0.399
1999 Bittigau P, Sifringer M, Pohl D, Stadthaus D, Ishimaru M, Shimizu H, Ikeda M, Lang D, Speer A, Olney JW, Ikonomidou C. Apoptotic neurodegeneration following trauma is markedly enhanced in the immature brain. Annals of Neurology. 45: 724-35. PMID 10360764 DOI: 10.1002/1531-8249(199906)45:6<724::Aid-Ana6>3.0.Co;2-P  0.362
1999 Ishimaru MJ, Ikonomidou C, Tenkova TI, Der TC, Dikranian K, Sesma MA, Olney JW. Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brain. The Journal of Comparative Neurology. 408: 461-76. PMID 10340498 DOI: 10.1002/(Sici)1096-9861(19990614)408:4<461::Aid-Cne2>3.0.Co;2-9  0.421
1999 Pohl D, Bittigau P, Ishimaru MJ, Stadthaus D, Hübner C, Olney JW, Turski L, Ikonomidou C. N-Methyl-D-aspartate antagonists and apoptotic cell death triggered by head trauma in developing rat brain. Proceedings of the National Academy of Sciences of the United States of America. 96: 2508-13. PMID 10051673 DOI: 10.1073/Pnas.96.5.2508  0.394
1999 Izumi Y, Kirby CO, Benz AM, Olney JW, Zorumski CF. Müller cell swelling, glutamate uptake, and excitotoxic neurodegeneration in the isolated rat retina. Glia. 25: 379-89. PMID 10028920 DOI: 10.1002/(Sici)1098-1136(19990215)25:4<379::Aid-Glia7>3.0.Co;2-7  0.435
1999 Chen Q, Olney JW, Price MT, Romano C. Biochemical and morphological analysis of non-NMDA receptor mediated excitotoxicity in chick embryo retina. Visual Neuroscience. 16: 131-9. PMID 10022484 DOI: 10.1017/S095252389916108X  0.423
1999 Brosnan-Watters G, Wozniak DF, Nardi A, Olney JW. Parallel recovery of MK-801-induced spatial learning impairment and neuronal injury in male mice. Pharmacology, Biochemistry, and Behavior. 62: 111-22. PMID 9972853 DOI: 10.1016/S0091-3057(98)00149-X  0.552
1999 Newcomer JW, Farber NB, Jevtovic-Todorovic V, Selke G, Melson AK, Hershey T, Craft S, Olney JW. Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 106-18. PMID 9885791 DOI: 10.1016/S0893-133X(98)00067-0  0.336
1999 Ikonomidou C, Bosch F, Miksa M, Bittigau P, Vöckler J, Dikranian K, Tenkova TI, Stefovska V, Turski L, Olney JW. Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain. Science (New York, N.Y.). 283: 70-4. PMID 9872743 DOI: 10.1126/Science.283.5398.70  0.482
1999 Jevtovic-Todorovic V, Benshoff N, Olney JW. 812 Nitrous Oxide Augments the Neurotoxic Side Effects of Ketamine in the Adult Rat Brain Journal of Neurosurgical Anesthesiology. 11: 328. DOI: 10.1097/00008506-199910000-00114  0.332
1998 Olney JW, Wozniak DF, Farber NB. Glumate receptor dysfunction and Alzheimer's disease. Restorative Neurology and Neuroscience. 13: 75-83. PMID 12671289  0.576
1998 Wozniak DF, Dikranian K, Ishimaru MJ, Nardi A, Corso TD, Tenkova T, Olney JW, Fix AS. Disseminated corticolimbic neuronal degeneration induced in rat brain by MK-801: potential relevance to Alzheimer's disease. Neurobiology of Disease. 5: 305-22. PMID 10069574 DOI: 10.1006/Nbdi.1998.0206  0.651
1998 Farber NB, Newcomer JW, Olney JW. The glutamate synapse in neuropsychiatric disorders. Focus on schizophrenia and Alzheimer's disease. Progress in Brain Research. 116: 421-37. PMID 9932393 DOI: 10.1016/S0079-6123(08)60453-7  0.377
1998 Mennerick S, Jevtovic-Todorovic V, Todorovic SM, Shen W, Olney JW, Zorumski CF. Effect of nitrous oxide on excitatory and inhibitory synaptic transmission in hippocampal cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9716-26. PMID 9822732 DOI: 10.1523/Jneurosci.18-23-09716.1998  0.382
1998 Romano C, Chen Q, Olney JW. The intact isolated (ex vivo) retina as a model system for the study of excitotoxicity. Progress in Retinal and Eye Research. 17: 465-83. PMID 9777647 DOI: 10.1016/S1350-9462(98)00008-1  0.321
1998 Chen Q, Olney JW, Lukasiewicz PD, Almli T, Romano C. Fenamates protect neurons against ischemic and excitotoxic injury in chick embryo retina. Neuroscience Letters. 242: 163-6. PMID 9530931 DOI: 10.1016/S0304-3940(98)00081-0  0.416
1998 Jevtovic-Todorovic V, Wozniak DF, Powell S, Nardi A, Olney JW. Clonidine potentiates the neuropathic pain-relieving action of MK-801 while preventing its neurotoxic and hyperactivity side effects. Brain Research. 781: 202-11. PMID 9507131 DOI: 10.1016/S0006-8993(97)01247-X  0.558
1998 Farber NB, Hanslick J, Kirby C, McWilliams L, Olney JW. Serotonergic agents that activate 5HT2A receptors prevent NMDA antagonist neurotoxicity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 18: 57-62. PMID 9408919 DOI: 10.1016/S0893-133X(97)00127-9  0.326
1998 Jevtovic-Todorovic V, Benshoff N, Olney JW. Prolonged nitrous oxide anesthesia kills neurons in the adult rat brain. Journal of Neurosurgical Anesthesiology. 10: 257. DOI: 10.1097/00008506-199810000-00014  0.365
1998 Jevtovic-Todorovic V, Benshoff N, Olney JW. EFFECTS OF AGE AND SEX ON NEUROTOXICITY CAUSED BY AN NMDA ANTAGONIST NITROUS OXIDE IN RAT CORTEX Anesthesiology. 89: 137A. DOI: 10.1097/00000542-199809040-00041  0.365
1998 Olney JW, Wozniak DF, Farber NB. Glutamate receptor dysfunction and Alzheimer's disease Restorative Neurology and Neuroscience. 13: 75-83.  0.495
1997 Olney JW, Wozniak DF, Farber NB. Excitotoxic neurodegeneration in Alzheimer disease. New hypothesis and new therapeutic strategies. Archives of Neurology. 54: 1234-40. PMID 9341569 DOI: 10.1001/Archneur.1997.00550220042012  0.618
1997 Corso TD, Sesma MA, Tenkova TI, Der TC, Wozniak DF, Farber NB, Olney JW. Multifocal brain damage induced by phencyclidine is augmented by pilocarpine. Brain Research. 752: 1-14. PMID 9106435 DOI: 10.1016/S0006-8993(96)01347-9  0.635
1997 Jevtović-Todorović V, Kirby CO, Olney JW. Isoflurane and propofol block neurotoxicity caused by MK-801 in the rat posterior cingulate/retrosplenial cortex. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 168-74. PMID 9040496 DOI: 10.1097/00004647-199702000-00006  0.466
1996 Farber NB, Foster J, Duhan NL, Olney JW. Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity. Schizophrenia Research. 21: 33-7. PMID 8998274 DOI: 10.1016/0920-9964(96)00024-2  0.431
1996 Wozniak DF, Brosnan-Watters G, Nardi A, McEwen M, Corso TD, Olney JW, Fix AS. MK-801 neurotoxicity in male mice: histologic effects and chronic impairment in spatial learning. Brain Research. 707: 165-79. PMID 8919293 DOI: 10.1016/0006-8993(95)01230-3  0.577
1996 Brosnan-Watters G, Wozniak DF, Nardi A, Olney JW. Acute behavioral effects of MK-801 in the mouse. Pharmacology, Biochemistry, and Behavior. 53: 701-11. PMID 8866975 DOI: 10.1016/0091-3057(95)02073-X  0.523
1996 Izumi Y, Kirby-Sharkey CO, Benz AM, Mennerick S, Labruyere J, Price MT, Olney JW, Zorumski CF. Swelling of Müller cells induced by AP3 and glutamate transport substrates in rat retina. Glia. 17: 285-93. PMID 8856325 DOI: 10.1002/(Sici)1098-1136(199608)17:4<285::Aid-Glia3>3.0.Co;2-Z  0.336
1996 Ikonomidou C, Qin Qin Y, Labruyere J, Olney JW. Motor neuron degeneration induced by excitotoxin agonists has features in common with those seen in the SOD-1 transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuropathology and Experimental Neurology. 55: 211-24. PMID 8786380 DOI: 10.1097/00005072-199602000-00010  0.36
1996 Ikonomidou C, Qin Y, Labruyere J, Kirby C, Olney JW. Prevention of trauma-induced neurodegeneration in infant rat brain. Pediatric Research. 39: 1020-7. PMID 8725264 DOI: 10.1203/00006450-199606000-00015  0.463
1995 Izumi Y, Kirby-Sharkey CO, Benz AM, Labruyere J, Price MT, Wozniak DF, Zorumski CF, Olney JW. Age dependent sensitivity of the rat retina to the excitotoxic action of N-methyl-D-aspartate. Neurobiology of Disease. 2: 139-44. PMID 9173997 DOI: 10.1006/Nbdi.1995.0015  0.609
1995 Farber NB, Wozniak DF, Price MT, Labruyere J, Huss J, St Peter H, Olney JW. Age-specific neurotoxicity in the rat associated with NMDA receptor blockade: potential relevance to schizophrenia? Biological Psychiatry. 38: 788-96. PMID 8750036 DOI: 10.1016/0006-3223(95)00046-1  0.613
1995 Olney JW, Farber NB. NMDA antagonists as neurotherapeutic drugs, psychotogens, neurotoxins, and research tools for studying schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 13: 335-45. PMID 8747758 DOI: 10.1016/0893-133X(95)00079-S  0.395
1995 Fix AS, Wozniak DF, Truex LL, McEwen M, Miller JP, Olney JW. Quantitative analysis of factors influencing neuronal necrosis induced by MK-801 in the rat posterior cingulate/retrosplenial cortex. Brain Research. 696: 194-204. PMID 8574669 DOI: 10.1016/0006-8993(95)00842-E  0.573
1995 Stewart GR, Olney JW, Schmidt RE, Wozniak DF. Mineralization of the globus pallidus following excitotoxic lesions of the basal forebrain. Brain Research. 695: 81-7. PMID 8574652 DOI: 10.1016/0006-8993(95)00864-M  0.557
1995 Izumi Y, Benz AM, Kurby CO, Labruyere J, Zorumski CF, Price MT, Olney JW. An ex vivo rat retinal preparation for excitotoxicity studies. Journal of Neuroscience Methods. 60: 219-25. PMID 8544482 DOI: 10.1016/0165-0270(95)00015-M  0.355
1995 Price MT, Romano C, Fix AS, Tizzano JP, Olney JW. Blockade of the second messenger functions of the glutamate metabotropic receptor is associated with degenerative changes in the retina and brain of immature rodents. Neuropharmacology. 34: 1069-79. PMID 8532156 DOI: 10.1016/0028-3908(95)00065-E  0.345
1995 Zhang SX, Weilersbacher GS, Henderson SW, Corso T, Olney JW, Langlais PJ. Excitotoxic cytopathology, progression, and reversibility of thiamine deficiency-induced diencephalic lesions. Journal of Neuropathology and Experimental Neurology. 54: 255-67. PMID 7876893 DOI: 10.1097/00005072-199503000-00012  0.378
1995 Romano C, Price MT, Olney JW. Delayed excitotoxic neurodegeneration induced by excitatory amino acid agonists in isolated retina. Journal of Neurochemistry. 65: 59-67. PMID 7790896 DOI: 10.1046/J.1471-4159.1995.65010059.X  0.432
1995 Romano C, Sesma MA, McDonald CT, O'Malley K, Van den Pol AN, Olney JW. Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. The Journal of Comparative Neurology. 355: 455-69. PMID 7636025 DOI: 10.1002/Cne.903550310  0.386
1995 Farber NB, Foster J, Duhan NL, Olney JW. alpha 2 adrenergic agonists prevent MK-801 neurotoxicity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 12: 347-9. PMID 7576011 DOI: 10.1016/0893-133X(95)00048-I  0.447
1995 Ishimaru M, Fukamauchi F, Olney JW. Halothane prevents MK-801 neurotoxicity in the rat cingulate cortex. Neuroscience Letters. 193: 1-4. PMID 7566654 DOI: 10.1016/0304-3940(95)11650-L  0.424
1995 Rothman SM, Olney JW. Excitotoxicity and the NMDA receptor--still lethal after eight years. Trends in Neurosciences. 18: 57-8. PMID 7537407 DOI: 10.1016/0166-2236(95)80017-V  0.362
1995 Olney JW, Farber NB. Glutamate receptor dysfunction and schizophrenia. Archives of General Psychiatry. 52: 998-1007. PMID 7492260 DOI: 10.1001/Archpsyc.1995.03950240016004  0.371
1995 Farber N, Foster J, Olney J. Clozapine and related analogs back NMDA antagonist neurotoxicity: Implications for schizophrenia Schizophrenia Research. 15: 57-58. DOI: 10.1016/0920-9964(95)95182-9  0.32
1995 Olney JW. NMDA receptor hypofunction, excitotoxicity, and Alzheimer's disease Neurobiology of Aging. 16: 459-461. DOI: 10.1016/0197-4580(94)00185-4  0.353
1994 Wozniak DF, Huss J, Olney JW. Quisqualate injection into the nucleus basalis magnocellularis produces seizure-related brain damage that is prevented by MK-801. Experimental Neurology. 126: 101-11. PMID 8157120 DOI: 10.1006/Exnr.1994.1046  0.569
1994 Olney JW. Excitatory transmitter neurotoxicity. Neurobiology of Aging. 15: 259-60. PMID 7838306 DOI: 10.1016/0197-4580(94)90127-9  0.342
1994 Olney JW. Neurotoxicity of NMDA receptor antagonists: an overview. Psychopharmacology Bulletin. 30: 533-40. PMID 7770617  0.328
1994 Farber NB, Price MT, Labruyere J, Nemnich J, Peter HS, Wozniak DF, Olney JW. Response Biological Psychiatry. 36: 209-210. DOI: 10.1016/0006-3223(94)91233-5  0.377
1994 Fix AS, Long GG, Wozniak DF, Olney JW. Pathomorphologic effects of N-methyl-D-aspartate antagonists in the rat posterior cingulate/retrosplenial cerebral cortex: A review Drug Development Research. 32: 147-152. DOI: 10.1002/Ddr.430320304  0.633
1993 Zorumski CF, Yamada KA, Price MT, Olney JW. A benzodiazepine recognition site associated with the non-NMDA glutamate receptor. Neuron. 10: 61-7. PMID 8427702 DOI: 10.1016/0896-6273(93)90242-J  0.406
1993 Fix AS, Horn JW, Wightman KA, Johnson CA, Long GG, Storts RW, Farber N, Wozniak DF, Olney JW. Neuronal vacuolization and necrosis induced by the noncompetitive N-methyl-D-aspartate (NMDA) antagonist MK(+)801 (dizocilpine maleate): a light and electron microscopic evaluation of the rat retrosplenial cortex. Experimental Neurology. 123: 204-15. PMID 8405286 DOI: 10.1006/Exnr.1993.1153  0.628
1993 Farber NB, Price MT, Labruyere J, Nemnich J, St Peter H, Wozniak DF, Olney JW. Antipsychotic drugs block phencyclidine receptor-mediated neurotoxicity. Biological Psychiatry. 34: 119-21. PMID 8373932 DOI: 10.1016/0006-3223(93)90265-F  0.534
1993 Zorumski CF, Olney JW. Excitotoxic neuronal damage and neuropsychiatric disorders. Pharmacology & Therapeutics. 59: 145-62. PMID 7904075 DOI: 10.1016/0163-7258(93)90043-D  0.365
1992 Fink-Jensen A, Judge ME, Hansen JB, Jacobsen P, Turski L, Olney J, Honoré T. Inhibition of cisplatin-induced emesis in ferrets by the non-NMDA receptor antagonists NBQX and CNQX. Neuroscience Letters. 137: 173-7. PMID 1350077 DOI: 10.1016/0304-3940(92)90397-P  0.38
1991 Olney JW, Labruyere J, Wang G, Wozniak DF, Price MT, Sesma MA. NMDA antagonist neurotoxicity: mechanism and prevention. Science (New York, N.Y.). 254: 1515-8. PMID 1835799 DOI: 10.1126/Science.1835799  0.632
1991 Mosinger JL, Price MT, Bai HY, Xiao H, Wozniak DF, Olney JW. Blockade of both NMDA and non-NMDA receptors is required for optimal protection against ischemic neuronal degeneration in the in vivo adult mammalian retina. Experimental Neurology. 113: 10-7. PMID 1828433 DOI: 10.1016/0014-4886(91)90140-8  0.633
1991 Wozniak DF, Stewart GR, Miller JP, Olney JW. Age-related sensitivity to kainate neurotoxicity. Experimental Neurology. 114: 250-3. PMID 1748199 DOI: 10.1016/0014-4886(91)90042-B  0.581
1991 Stewart GR, Olney JW, Pathikonda M, Snider WD. Excitotoxicity in the embryonic chick spinal cord. Annals of Neurology. 30: 758-66. PMID 1686386 DOI: 10.1002/Ana.410300604  0.35
1990 Clifford DB, Olney JW, Benz AM, Fuller TA, Zorumski CF. Ketamine, phencyclidine, and MK-801 protect against kainic acid-induced seizure-related brain damage. Epilepsia. 31: 382-90. PMID 2196169 DOI: 10.1111/J.1528-1157.1990.Tb05492.X  0.375
1990 Wozniak DF, Olney JW, Kettinger L, Price M, Miller JP. Behavioral effects of MK-801 in the rat. Psychopharmacology. 101: 47-56. PMID 2188277 DOI: 10.1007/Bf02253717  0.545
1990 Olney JW, Zorumski C, Price MT, Labruyere J. L-cysteine, a bicarbonate-sensitive endogenous excitotoxin. Science (New York, N.Y.). 248: 596-9. PMID 2185543 DOI: 10.1126/Science.2185543  0.36
1990 Stewart GR, Zorumski CF, Price MT, Olney JW. Domoic acid: a dementia-inducing excitotoxic food poison with kainic acid receptor specificity. Experimental Neurology. 110: 127-38. PMID 2170163 DOI: 10.1016/0014-4886(90)90057-Y  0.448
1990 Olney JW. Excitotoxin-mediated neuron death in youth and old age. Progress in Brain Research. 86: 37-51. PMID 1982368 DOI: 10.1016/S0079-6123(08)63165-9  0.419
1990 Olney JW, Zorumski CF, Stewart GR, Price MT, Wang GJ, Labruyere J. Excitotoxicity of L-dopa and 6-OH-dopa: implications for Parkinson's and Huntington's diseases. Experimental Neurology. 108: 269-72. PMID 1972067 DOI: 10.1016/0014-4886(90)90134-E  0.341
1990 Olney JW, Labruyere J, Price MT. In Reply: Phencyclidine, Dizocilpine, and Cerebrocortical Neurons Science. 247: 221-221. DOI: 10.1126/Science.247.4939.221-A  0.309
1989 Mosinger JL, Olney JW. Photothrombosis-induced ischemic neuronal degeneration in the rat retina. Experimental Neurology. 105: 110-3. PMID 2744125 DOI: 10.1016/0014-4886(89)90178-7  0.384
1989 Wozniak DF, Stewart GR, Finger S, Olney JW. Comparison of behavioral effects of nucleus basalis magnocellularis lesions and somatosensory cortex ablation in the rat. Neuroscience. 32: 685-700. PMID 2689907 DOI: 10.1016/0306-4522(89)90290-X  0.542
1989 Ikonomidou C, Mosinger JL, Salles KS, Labruyere J, Olney JW. Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 2809-18. PMID 2671294 DOI: 10.1523/Jneurosci.09-08-02809.1989  0.44
1989 Clifford DB, Zorumski CF, Olney JW. Ketamine and MK-801 prevent degeneration of thalamic neurons induced by focal cortical seizures. Experimental Neurology. 105: 272-9. PMID 2670599 DOI: 10.1016/0014-4886(89)90130-1  0.421
1989 Olney JW, Labruyere J, Price MT. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science (New York, N.Y.). 244: 1360-2. PMID 2660263 DOI: 10.1126/Science.2660263  0.43
1989 Wozniak DF, Stewart GR, Finger S, Olney JW, Cozzari C. Basal forebrain lesions impair tactile discrimination and working memory. Neurobiology of Aging. 10: 173-9. PMID 2657465 DOI: 10.1016/0197-4580(89)90027-4  0.551
1989 Olney JW, Ikonomidou C, Mosinger JL, Frierdich G. MK-801 prevents hypobaric-ischemic neuronal degeneration in infant rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 1701-4. PMID 2656934 DOI: 10.1523/Jneurosci.09-05-01701.1989  0.488
1989 Olney JW. Glutamate, a neurotoxic transmitter. Journal of Child Neurology. 4: 218-26. PMID 2570095 DOI: 10.1177/088307388900400315  0.354
1989 Ikonomidou C, Price MT, Mosinger JL, Frierdich G, Labruyere J, Salles KS, Olney JW. Hypobaric-ischemic conditions produce glutamate-like cytopathology in infant rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 1693-700. PMID 2566662 DOI: 10.1523/Jneurosci.09-05-01693.1989  0.455
1989 Ikonomidou C, Mosinger JL, Olney JW. Hypothermia enhances protective effect of MK-801 against hypoxic/ischemic brain damage in infant rats. Brain Research. 487: 184-7. PMID 2546648 DOI: 10.1016/0006-8993(89)90956-6  0.427
1989 Olney JW, Labruyere J, Price MT. Neurocytotoxicity of phencyclidine and MK-801 Biological Psychiatry. 25: A133. DOI: 10.1016/0006-3223(89)91755-1  0.333
1988 Olney JW. Excitotoxic food additives: functional teratological aspects. Progress in Brain Research. 73: 283-94. PMID 3047798 DOI: 10.1016/S0079-6123(08)60510-5  0.379
1987 Scallet AC, Faris PL, Beinfeld MC, Olney JW. Hypothalamic neurotoxins alter the content of immunoreactive cholecystokinin in pituitary. Brain Research. 407: 390-3. PMID 3567652 DOI: 10.1016/0006-8993(87)91120-6  0.321
1987 Clifford DB, Olney JW, Maniotis A, Collins RC, Zorumski CF. The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures. Neuroscience. 23: 953-68. PMID 3437996 DOI: 10.1016/0306-4522(87)90171-0  0.337
1987 Olney J, Price M, Salles KS, Labruyere J, Frierdich G. MK-801 powerfully protects against N-methyl aspartate neurotoxicity European Journal of Pharmacology. 141: 357-361. PMID 3311770 DOI: 10.1016/0014-2999(87)90552-8  0.351
1987 Olney JW, Price MT, Salles KS, Labruyere J, Ryerson R, Mahan K, Frierdich G, Samson L. L-homocysteic acid: an endogenous excitotoxic ligand of the NMDA receptor. Brain Research Bulletin. 19: 597-602. PMID 2891418 DOI: 10.1016/0361-9230(87)90077-3  0.38
1987 Pullan LM, Olney JW, Price MT, Compton RP, Hood WF, Michel J, Monahan JB. Excitatory amino acid receptor potency and subclass specificity of sulfur-containing amino acids. Journal of Neurochemistry. 49: 1301-7. PMID 2887637 DOI: 10.1111/J.1471-4159.1987.Tb10024.X  0.318
1987 Olney JW, Price MT, Labruyere J, Salles KS, Frierdich G, Mueller M, Silverman E. Anti-parkinsonian agents are phencyclidine agonists and N-methyl-aspartate antagonists. European Journal of Pharmacology. 142: 319-20. PMID 2826182 DOI: 10.1016/0014-2999(87)90123-3  0.306
1987 Rothman SM, Olney JW. Excitotoxity and the NMDA receptor Trends in Neurosciences. 10: 299-302. DOI: 10.1016/0166-2236(87)90177-9  0.448
1986 Olney JW, Price MT, Fuller TA, Labruyere J, Samson L, Carpenter M, Mahan K. The anti-excitotoxic effects of certain anesthetics, analgesics and sedative-hypnotics. Neuroscience Letters. 68: 29-34. PMID 3523314 DOI: 10.1016/0304-3940(86)90224-7  0.358
1986 Stewart GR, Price M, Olney JW, Hartman BK, Cozzari C. N-methylaspartate: an effective tool for lesioning basal forebrain cholinergic neurons of the rat. Brain Research. 369: 377-82. PMID 3516311 DOI: 10.1016/0006-8993(86)90555-X  0.36
1986 Olney JW, Price MT, Samson L, Labruyere J. The role of specific ions in glutamate neurotoxicity. Neuroscience Letters. 65: 65-71. PMID 2871531 DOI: 10.1016/0304-3940(86)90121-7  0.33
1986 Rothman SM, Olney JW. Glutamate and the pathophysiology of hypoxic--ischemic brain damage. Annals of Neurology. 19: 105-11. PMID 2421636 DOI: 10.1002/Ana.410190202  0.433
1985 Olney JW. Excitatory transmitters and epilepsy-related brain damage. International Review of Neurobiology. 27: 337-62. PMID 2867981 DOI: 10.1016/S0074-7742(08)60561-9  0.361
1985 Price MT, Olney JW, Samson L, Labruyere J. Calcium influx accompanies but does not cause excitotoxin-induced neuronal necrosis in retina. Brain Research Bulletin. 14: 369-76. PMID 2860956 DOI: 10.1016/0361-9230(85)90197-2  0.319
1984 Price MT, Pusateri ME, Crow SE, Buchsbaum S, Olney JW, Lowry OH. Uptake of exogenous aspartate into circumventricular organs but not other regions of adult mouse brain. Journal of Neurochemistry. 42: 740-4. PMID 6693901 DOI: 10.1111/J.1471-4159.1984.Tb02745.X  0.349
1983 Olney JW, deGubareff T, Sloviter RS. "Epileptic" brain damage in rats induced by sustained electrical stimulation of the perforant path. II. Ultrastructural analysis of acute hippocampal pathology. Brain Research Bulletin. 10: 699-712. PMID 6871738 DOI: 10.1016/0361-9230(83)90038-2  0.394
1983 Olney JW, de Gubareff T, Labruyere J. Seizure-related brain damage induced by cholinergic agents. Nature. 301: 520-2. PMID 6823330 DOI: 10.1038/301520A0  0.361
1983 Young E, Olney J, Akil H. Selective alterations of opiate receptor subtypes in monosodium glutamate-treated rats Journal of Neurochemistry. 40: 1558-1564. PMID 6304248 DOI: 10.1111/J.1471-4159.1983.Tb08126.X  0.393
1983 Olney JW, Price MT. Excitotoxic amino acids as neuroendocrine research tools. Methods in Enzymology. 103: 379-93. PMID 6142399 DOI: 10.1016/S0076-6879(83)03026-8  0.357
1982 Olney JW, Collins JF, De Gubareff T. Dipiperidinoethane neurotoxicity clarified. Brain Research. 249: 195-7. PMID 7139296 DOI: 10.1016/0006-8993(82)90189-5  0.325
1982 Fuller TA, Olney JW, Conboy VT. Naloxone blocks morphine enhancement of kainic acid neurotoxicity. Life Sciences. 31: 229-33. PMID 6289030 DOI: 10.1016/0024-3205(82)90582-3  0.314
1982 Olney JW. The toxic effects of glutamate and related compounds in the retina and the brain. Retina (Philadelphia, Pa.). 2: 341-59. PMID 6152914 DOI: 10.1097/00006982-198200000-00020  0.38
1981 Price MT, Olney JW, Haft R. Age-related changes in glutamate concentration and synaptosomal glutamate uptake in adult rat striatum. Life Sciences. 28: 1365-70. PMID 7242238 DOI: 10.1016/0024-3205(81)90410-0  0.328
1981 Olney JW, Fuller TA, de Gubareff T. Kainate-like neurotoxicity of folates. Nature. 292: 165-7. PMID 6972487 DOI: 10.1038/292165A0  0.403
1981 Price MT, Olney JW, Lowry OH, Buchsbaum S. Uptake of exogenous glutamate and aspartate by circumventricular organs but not other regions of brain. Journal of Neurochemistry. 36: 1774-80. PMID 6113269 DOI: 10.1111/J.1471-4159.1981.Tb00430.X  0.385
1980 Schwob JE, Fuller T, Price JL, Olney JW. Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: a histological study. Neuroscience. 5: 991-1014. PMID 7402461 DOI: 10.1016/0306-4522(80)90181-5  0.37
1980 Olney JW, Price MT. Neuroendocrine interactions of excitatory and inhibitory amino acids Brain Research Bulletin. 5: 361-368. DOI: 10.1016/0361-9230(80)90058-1  0.394
1979 Olney JW, de Gubareff T, Labruyere J. alpha-Aminoadipate blocks the neurotoxic action of N-methyl aspartate. Life Sciences. 25: 537-40. PMID 491849 DOI: 10.1016/0024-3205(79)90567-8  0.42
1979 Olney JW, Fuller T, de Gubareff T. Acute dendrotoxic changes in the hippocampus of kainate treated rats. Brain Research. 176: 91-100. PMID 487185 DOI: 10.1016/0006-8993(79)90872-2  0.383
1979 Fuller TA, Olney JW. Effects of morphine or naloxone on kainic acid neurotoxicity. Life Sciences. 24: 1793-8. PMID 459681 DOI: 10.1016/0024-3205(79)90069-9  0.386
1979 Perez VJ, Olney JW, Martin JF, Cannon WO. Minimal tissue concentrations of glutamate required to produce necrosis of hypothalamic neurons in newborn mice. Biology of the Neonate. 35: 17-22. PMID 420883 DOI: 10.1159/000241149  0.394
1978 Price MT, Olney JW, Cicero TJ. Acute elevations of serum luteinizing hormone induced by kainic acid, N-methyl aspartic acid or homocysteic acid. Neuroendocrinology. 26: 352-8. PMID 692809 DOI: 10.1159/000122790  0.366
1978 Olney JW, de Gubareff T. Glutamate neurotoxicity and Huntington's chorea. Nature. 271: 557-9. PMID 146165 DOI: 10.1038/271557A0  0.439
1977 Olney JW, Rhee V, Gubareff TD. Neurotoxic effects of glutamate on mouse area postrema. Brain Research. 120: 151-7. PMID 832113 DOI: 10.1016/0006-8993(77)90506-6  0.362
1977 Price MT, Olney JW, Cicero TJ. Proliferation of lamellar whorls in arcuate neurons of the hypothalamus of male rats treated with estradiol benzoate or cyproterone acetate. Cell and Tissue Research. 182: 537-40. PMID 336213 DOI: 10.1007/Bf00219835  0.332
1976 Olney JW, Misra CH, Rhee V. Brain and retinal damage from lathyrus excitotoxin, beta-N-oxalyl-L-alpha,beta-diaminopropionic acid. Nature. 264: 659-61. PMID 1004610 DOI: 10.1038/264659A0  0.347
1976 Perez VJ, Olney JW, Frolichstein CF, Martin JF, Cannon WO. Regional uptake of neurotoxic and nontoxic amino acids in vivo by the infant mouse brain. Biochemical Pharmacology. 25: 1415-9. PMID 938563 DOI: 10.1016/0006-2952(76)90112-X  0.398
1976 Olney JW. Brain damage and oral intake of certain amino acids. Advances in Experimental Medicine and Biology. 69: 497-506. PMID 821314 DOI: 10.1007/978-1-4684-3264-0_36  0.302
1976 Price MT, Olney JW, Cicero TJ. Proliferation of lamellar whorls in arcuate neurons of the hypothalamus of castrated and morphine-treated male rats. Cell and Tissue Research. 171: 277-84. PMID 788916 DOI: 10.1007/Bf00224653  0.332
1975 Misra CH, Olney JW. Cysteine oxidase in brain. Brain Research. 97: 117-26. PMID 1175028 DOI: 10.1016/0006-8993(75)90918-X  0.341
1975 Shapre LG, Olney JW, Ohlendorf C, Lyss A, Zimmerman M, Gale B. Brain damage and associated behavioral deficits following the administration of L-cysteine to infant rats. Pharmacology, Biochemistry, and Behavior. 3: 291-8. PMID 1144485 DOI: 10.1016/0091-3057(75)90160-4  0.318
1975 Olney JW, Misra CH, de Gubareff T. Cysteine-S-sulfate: brain damaging metabolite in sulfite oxidase deficiency. Journal of Neuropathology and Experimental Neurology. 34: 167-77. PMID 1123650 DOI: 10.1097/00005072-197503000-00005  0.363
1974 Olney JW, Rhee V, Ho OL. Kainic acid: a powerful neurotoxic analogue of glutamate. Brain Research. 77: 507-12. PMID 4152936 DOI: 10.1016/0006-8993(74)90640-4  0.301
1973 Perez VJ, Olney JW, Robin SJ. Glutamate accumulation in infant mouse hypothalamus: influence of temperature. Brain Research. 59: 181-9. PMID 4747750 DOI: 10.1016/0006-8993(73)90259-X  0.305
1973 Olney JW, Ho OL, Rhee V. Brain-damaging potential of protein hydrolysates. The New England Journal of Medicine. 289: 391-5. PMID 4198222 DOI: 10.1056/Nejm197308232890802  0.377
1973 Olney JW. Status of monosodium glutamate revisited. The American Journal of Clinical Nutrition. 26: 683-5. PMID 4197462 DOI: 10.1093/Ajcn/26.6.683  0.332
1972 Olney JW, Ho OL, Rhee V, Schainker B. Cysteine-induced brain damage in infant and fetal rodents. Brain Research. 45: 309-13. PMID 5075344 DOI: 10.1016/0006-8993(72)90243-0  0.325
1972 Perez VJ, Olney JW. Accumulation of glutamic acid in the arcuate nucleus of the hypothalamus of the infant mouse followng subcutaneous administration of monosodium glutamate. Journal of Neurochemistry. 19: 1777-82. PMID 5042473 DOI: 10.1111/J.1471-4159.1972.Tb06222.X  0.408
1972 Olney JW, Sharpe LG, Feigin RD. Glutamate-induced brain damage in infant primates. Journal of Neuropathology and Experimental Neurology. 31: 464-88. PMID 4626680 DOI: 10.1097/00005072-197207000-00006  0.348
1971 Olney JW. Glutamate-induced neuronal necrosis in the infant mouse hypothalamus. An electron microscopic study. Journal of Neuropathology and Experimental Neurology. 30: 75-90. PMID 5542543 DOI: 10.1097/00005072-197101000-00008  0.365
1971 Olney JW, Ho OL, Rhee V. Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system. Experimental Brain Research. 14: 61-76. PMID 5157537 DOI: 10.1007/Bf00234911  0.365
1971 Olney JW, Adamo NJ, Ratner A. Monosodium glutamate effects. Science (New York, N.Y.). 172: 294. PMID 5102256 DOI: 10.1126/Science.172.3980.294  0.348
1970 Olney JW, Ho OL. Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine. Nature. 227: 609-11. PMID 5464249 DOI: 10.1038/227609B0  0.397
1970 Lowe CU, Zavon MR, Olney JW, Sharpe LG. Monosodium glutamate: specific brain lesion questioned. Science (New York, N.Y.). 167: 1016-7. PMID 4983437 DOI: 10.1126/Science.167.3920.1016  0.359
1969 Olney JW, Sharpe LG. Brain lesions in an infant rhesus monkey treated with monsodium glutamate. Science (New York, N.Y.). 166: 386-8. PMID 5812037 DOI: 10.1126/Science.166.3903.386  0.428
1969 Olney JW. Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science (New York, N.Y.). 164: 719-21. PMID 5778021 DOI: 10.1126/Science.164.3880.719  0.361
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