Norberto Aguirre - Publications

Pharmacology Universidad de Navarra, Pamplona, Navarra, Spain 

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Barros-Miñones L, Goñi-Allo B, Suquia V, Beitia G, Aguirre N, Puerta E. Contribution of dopamine to mitochondrial complex I inhibition and dopaminergic deficits caused by methylenedioxymethamphetamine in mice. Neuropharmacology. 93: 124-33. PMID 25666033 DOI: 10.1016/J.Neuropharm.2015.01.025  0.352
2015 Orejana L, Barros-Miñones L, Jordan J, Cedazo-Minguez A, Tordera RM, Aguirre N, Puerta E. Sildenafil Decreases BACE1 and Cathepsin B Levels and Reduces APP Amyloidogenic Processing in the SAMP8 Mouse. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 675-85. PMID 25063079 DOI: 10.1093/Gerona/Glu106  0.308
2014 Cuyas E, Robledo P, Pizarro N, Farré M, Puerta E, Aguirre N, de la Torre R. 3,4-methylenedioxymethamphetamine induces gene expression changes in rats related to serotonergic and dopaminergic systems, but not to neurotoxicity. Neurotoxicity Research. 25: 161-9. PMID 23949956 DOI: 10.1007/S12640-013-9416-1  0.338
2013 Orejana L, Barros-Miñones L, Aguirre N, Puerta E. Implication of JNK pathway on tau pathology and cognitive decline in a senescence-accelerated mouse model. Experimental Gerontology. 48: 565-71. PMID 23501261 DOI: 10.1016/J.Exger.2013.03.001  0.351
2013 Barros-Miñones L, Martín-de-Saavedra D, Perez-Alvarez S, Orejana L, Suquía V, Goñi-Allo B, Hervias I, López MG, Jordan J, Aguirre N, Puerta E. Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate. Biochimica Et Biophysica Acta. 1832: 705-17. PMID 23415811 DOI: 10.1016/J.Bbadis.2013.02.002  0.371
2013 Dobarro M, Orejana L, Aguirre N, Ramírez MJ. Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1351-60. PMID 23194475 DOI: 10.1017/S1461145712001393  0.304
2013 Barros-Miñones L, Orejana L, Goñi-Allo B, Suquía V, Hervías I, Aguirre N, Puerta E. Modulation of the ASK1-MKK3/6-p38/MAPK signalling pathway mediates sildenafil protection against chemical hypoxia caused by malonate. British Journal of Pharmacology. 168: 1820-34. PMID 23186227 DOI: 10.1111/Bph.12071  0.318
2013 Dobarro M, Orejana L, Aguirre N, Ramírez MJ. Propranolol restores cognitive deficits and improves amyloid and Tau pathologies in a senescence-accelerated mouse model. Neuropharmacology. 64: 137-44. PMID 22824191 DOI: 10.1016/J.Neuropharm.2012.06.047  0.338
2012 Martínez-Turrillas R, Puerta E, Chowdhury D, Marco S, Watanabe M, Aguirre N, Pérez-Otaño I. The NMDA receptor subunit GluN3A protects against 3-nitroproprionic-induced striatal lesions via inhibition of calpain activation. Neurobiology of Disease. 48: 290-8. PMID 22801082 DOI: 10.1016/J.Nbd.2012.07.001  0.342
2012 Puerta E, Barros-Miñones L, Hervias I, Gomez-Rodriguez V, Orejana L, Pizarro N, de la Torre R, Jordán J, Aguirre N. Long-lasting neuroprotective effect of sildenafil against 3,4-methylenedioxymethamphetamine- induced 5-hydroxytryptamine deficits in the rat brain. Journal of Neuroscience Research. 90: 518-28. PMID 21948520 DOI: 10.1002/Jnr.22759  0.404
2012 Orejana L, Barros-Miñones L, Jordán J, Puerta E, Aguirre N. Sildenafil ameliorates cognitive deficits and tau pathology in a senescence-accelerated mouse model. Neurobiology of Aging. 33: 625.e11-20. PMID 21546125 DOI: 10.1016/J.Neurobiolaging.2011.03.018  0.333
2011 Cuadrado-Tejedor M, Hervias I, Ricobaraza A, Puerta E, Pérez-Roldán JM, García-Barroso C, Franco R, Aguirre N, García-Osta A. Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease. British Journal of Pharmacology. 164: 2029-41. PMID 21627640 DOI: 10.1111/J.1476-5381.2011.01517.X  0.33
2011 Puerta E, Aguirre N. Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): Neurodegeneration versus neuromodulation Pharmaceuticals. 4: 992-1018. DOI: 10.3390/Ph4070992  0.354
2010 Perez-Alvarez S, Cuenca-Lopez MD, de Mera RM, Puerta E, Karachitos A, Bednarczyk P, Kmita H, Aguirre N, Galindo MF, Jordán J. Methadone induces necrotic-like cell death in SH-SY5Y cells by an impairment of mitochondrial ATP synthesis. Biochimica Et Biophysica Acta. 1802: 1036-47. PMID 20691259 DOI: 10.1016/J.Bbadis.2010.07.024  0.318
2010 Puerta E, Pastor F, Dvoracek J, de Saavedra MD, Goñi-Allo B, Jordán J, Hervias I, Aguirre N. Delayed pre-conditioning by 3-nitropropionic acid prevents 3,4-methylenedioxymetamphetamine-induced 5-HT deficits. Journal of Neurochemistry. 114: 843-52. PMID 20477949 DOI: 10.1111/J.1471-4159.2010.06808.X  0.353
2010 Puerta E, Hervias I, Goñi-Allo B, Zhang SF, Jordán J, Starkov AA, Aguirre N. Methylenedioxymethamphetamine inhibits mitochondrial complex I activity in mice: a possible mechanism underlying neurotoxicity. British Journal of Pharmacology. 160: 233-45. PMID 20423338 DOI: 10.1111/J.1476-5381.2010.00663.X  0.36
2010 Puerta E, Hervias I, Barros-Miñones L, Jordan J, Ricobaraza A, Cuadrado-Tejedor M, García-Osta A, Aguirre N. Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF. Neurobiology of Disease. 38: 237-45. PMID 20109548 DOI: 10.1016/J.Nbd.2010.01.013  0.35
2010 Garcia-Martinez EM, Sanz-Blasco S, Karachitos A, Bandez MJ, Fernandez-Gomez FJ, Perez-Alvarez S, de Mera RM, Jordan MJ, Aguirre N, Galindo MF, Villalobos C, Navarro A, Kmita H, Jordán J. Mitochondria and calcium flux as targets of neuroprotection caused by minocycline in cerebellar granule cells. Biochemical Pharmacology. 79: 239-50. PMID 19682437 DOI: 10.1016/J.Bcp.2009.07.028  0.34
2009 Puerta E, Hervias I, Aguirre N. On the mechanisms underlying 3,4-methylenedioxymethamphetamine toxicity: the dilemma of the chicken and the egg. Neuropsychobiology. 60: 119-29. PMID 19893329 DOI: 10.1159/000253548  0.348
2009 Puerta E, Hervias I, Goñi-Allo B, Lasheras B, Jordan J, Aguirre N. Phosphodiesterase 5 inhibitors prevent 3,4-methylenedioxymethamphetamine-induced 5-HT deficits in the rat. Journal of Neurochemistry. 108: 755-66. PMID 19187094 DOI: 10.1111/J.1471-4159.2008.05825.X  0.369
2008 Goñi-Allo B, Puerta E, Mathúna BO, Hervias I, Lasheras B, de la Torre R, Aguirre N. On the role of tyrosine and peripheral metabolism in 3,4-methylenedioxymethamphetamine-induced serotonin neurotoxicity in rats. Neuropharmacology. 54: 885-900. PMID 18329670 DOI: 10.1016/J.Neuropharm.2008.01.007  0.376
2008 Goni-Allo B, O Mathúna B, Segura M, Puerta E, Lasheras B, de la Torre R, Aguirre N. The relationship between core body temperature and 3,4-methylenedioxymethamphetamine metabolism in rats: implications for neurotoxicity. Psychopharmacology. 197: 263-78. PMID 18074122 DOI: 10.1007/S00213-007-1027-1  0.327
2008 Goñi-Allo B, Puerta E, Ramos M, Lasheras B, Jordán J, Aguirre N. Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK. Journal of Neurochemistry. 104: 914-25. PMID 17995929 DOI: 10.1111/J.1471-4159.2007.05042.X  0.323
2007 Jordan J, Fernandez-Gomez FJ, Ramos M, Ikuta I, Aguirre N, Galindo MF. Minocycline and cytoprotection: shedding new light on a shadowy controversy. Current Drug Delivery. 4: 225-31. PMID 17627496 DOI: 10.2174/156720107781023938  0.303
2007 Goñi-Allo B, Puerta E, Hervias I, Di Palma R, Ramos M, Lasheras B, Aguirre N. Studies on the mechanisms underlying amiloride enhancement of 3,4-methylenedioxymethamphetamine-induced serotonin depletion in rats. European Journal of Pharmacology. 562: 198-207. PMID 17320075 DOI: 10.1016/J.Ejphar.2007.01.049  0.37
2006 Goñi-Allo B, Ramos M, Herv'as I, Lasheras B, Aguirre N. Studies on striatal neurotoxicity caused by the 3,4-methylenedioxymethamphetamine/ malonate combination: implications for serotonin/dopamine interactions. Journal of Psychopharmacology (Oxford, England). 20: 245-56. PMID 16510482 DOI: 10.1177/0269881106063264  0.362
2005 Fernandez-Gomez FJ, Gomez-Lazaro M, Pastor D, Calvo S, Aguirre N, Galindo MF, Jordán J. Minocycline fails to protect cerebellar granular cell cultures against malonate-induced cell death. Neurobiology of Disease. 20: 384-91. PMID 16242643 DOI: 10.1016/J.Nbd.2005.03.019  0.37
2005 Aguirre N, Beal MF, Matson WR, Bogdanov MB. Increased oxidative damage to DNA in an animal model of amyotrophic lateral sclerosis. Free Radical Research. 39: 383-8. PMID 16028363 DOI: 10.1080/10715760400027979  0.454
2005 Fernandez-Gomez FJ, Galindo MF, Gomez-Lazaro M, González-García C, Ceña V, Aguirre N, Jordán J. Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions. Neuroscience. 133: 959-67. PMID 15964487 DOI: 10.1016/J.Neuroscience.2005.03.019  0.331
2005 Ramos M, Goñi-Allo B, Aguirre N. Ibotenic acid lesions of the medial prefrontal cortex block the development and expression of 3,4-methylenedioxymethamphetamine-induced behavioral sensitization in rats. Behavioural Brain Research. 160: 304-11. PMID 15863226 DOI: 10.1016/J.Bbr.2004.12.010  0.315
2005 Ramos M, Goñi-Allo B, Aguirre N. Administration of SCH 23390 into the medial prefrontal cortex blocks the expression of MDMA-induced behavioral sensitization in rats: an effect mediated by 5-HT2C receptor stimulation and not by D1 receptor blockade. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 2180-91. PMID 15841107 DOI: 10.1038/Sj.Npp.1300735  0.354
2005 Fernandez-Gomez FJ, Galindo MF, Gómez-Lázaro M, Yuste VJ, Comella JX, Aguirre N, Jordán J. Malonate induces cell death via mitochondrial potential collapse and delayed swelling through an ROS-dependent pathway. British Journal of Pharmacology. 144: 528-37. PMID 15655518 DOI: 10.1038/Sj.Bjp.0706069  0.315
2005 Goñi-Allo B, Ramos M, Jordán J, Aguirre N. In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-d-aspartate. Experimental Neurology. 191: 326-30. PMID 15649488 DOI: 10.1016/J.Expneurol.2004.10.010  0.302
2004 Ramos M, Goñi-Allo B, Aguirre N. Studies on the role of dopamine D1 receptors in the development and expression of MDMA-induced behavioral sensitization in rats. Psychopharmacology. 177: 100-10. PMID 15338099 DOI: 10.1007/S00213-004-1937-0  0.32
2003 Wu AS, Kiaei M, Aguirre N, Crow JP, Calingasan NY, Browne SE, Beal MF. Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis. Journal of Neurochemistry. 85: 142-50. PMID 12641736 DOI: 10.1046/J.1471-4159.2003.01639.X  0.546
2000 Hervías I, Lasheras B, Aguirre N. 2-Deoxy-D-glucose prevents and nicotinamide potentiates 3, 4-methylenedioxymethamphetamine-induced serotonin neurotoxicity. Journal of Neurochemistry. 75: 982-90. PMID 10936179 DOI: 10.1046/J.1471-4159.2000.0750982.X  0.392
2000 Barrionuevo M, Aguirre N, Del Río JD, Lasheras B. Serotonergic deficits and impaired passive-avoidance learning in rats by MDEA: a comparison with MDMA. Pharmacology, Biochemistry, and Behavior. 65: 233-40. PMID 10672974 DOI: 10.1016/S0091-3057(99)00170-7  0.376
1999 Aguirre N, Barrionuevo M, Ramírez MJ, Del Río J, Lasheras B. Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity. Neuroreport. 10: 3675-80. PMID 10619665 DOI: 10.1097/00001756-199911260-00039  0.388
1998 Aguirre N, Ballaz S, Lasheras B, Del Río J. MDMA ('Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion. European Journal of Pharmacology. 346: 181-8. PMID 9652358 DOI: 10.1016/S0014-2999(98)00062-4  0.357
1997 Aguirre N, Frechilla D, García-Osta A, Lasheras B, Del Río J. Differential regulation by methylenedioxymethamphetamine of 5-hydroxytryptamine1A receptor density and mRNA expression in rat hippocampus, frontal cortex, and brainstem: the role of corticosteroids. Journal of Neurochemistry. 68: 1099-105. PMID 9048755 DOI: 10.1046/J.1471-4159.1997.68031099.X  0.342
1995 Aguirre N, Galbete JL, Lasheras B, Del Río J. Methylenedioxymethamphetamine induces opposite changes in central pre- and postsynaptic 5-HT1A receptors in rats. European Journal of Pharmacology. 281: 101-5. PMID 8566108 DOI: 10.1016/0014-2999(95)00303-3  0.33
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