Year |
Citation |
Score |
2015 |
Barros-Miñones L, Goñi-Allo B, Suquia V, Beitia G, Aguirre N, Puerta E. Contribution of dopamine to mitochondrial complex I inhibition and dopaminergic deficits caused by methylenedioxymethamphetamine in mice. Neuropharmacology. 93: 124-33. PMID 25666033 DOI: 10.1016/J.Neuropharm.2015.01.025 |
0.352 |
|
2015 |
Orejana L, Barros-Miñones L, Jordan J, Cedazo-Minguez A, Tordera RM, Aguirre N, Puerta E. Sildenafil Decreases BACE1 and Cathepsin B Levels and Reduces APP Amyloidogenic Processing in the SAMP8 Mouse. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 675-85. PMID 25063079 DOI: 10.1093/Gerona/Glu106 |
0.308 |
|
2014 |
Cuyas E, Robledo P, Pizarro N, Farré M, Puerta E, Aguirre N, de la Torre R. 3,4-methylenedioxymethamphetamine induces gene expression changes in rats related to serotonergic and dopaminergic systems, but not to neurotoxicity. Neurotoxicity Research. 25: 161-9. PMID 23949956 DOI: 10.1007/S12640-013-9416-1 |
0.338 |
|
2013 |
Orejana L, Barros-Miñones L, Aguirre N, Puerta E. Implication of JNK pathway on tau pathology and cognitive decline in a senescence-accelerated mouse model. Experimental Gerontology. 48: 565-71. PMID 23501261 DOI: 10.1016/J.Exger.2013.03.001 |
0.351 |
|
2013 |
Barros-Miñones L, MartÃn-de-Saavedra D, Perez-Alvarez S, Orejana L, SuquÃa V, Goñi-Allo B, Hervias I, López MG, Jordan J, Aguirre N, Puerta E. Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate. Biochimica Et Biophysica Acta. 1832: 705-17. PMID 23415811 DOI: 10.1016/J.Bbadis.2013.02.002 |
0.371 |
|
2013 |
Dobarro M, Orejana L, Aguirre N, RamÃrez MJ. Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1351-60. PMID 23194475 DOI: 10.1017/S1461145712001393 |
0.304 |
|
2013 |
Barros-Miñones L, Orejana L, Goñi-Allo B, Suquía V, Hervías I, Aguirre N, Puerta E. Modulation of the ASK1-MKK3/6-p38/MAPK signalling pathway mediates sildenafil protection against chemical hypoxia caused by malonate. British Journal of Pharmacology. 168: 1820-34. PMID 23186227 DOI: 10.1111/Bph.12071 |
0.318 |
|
2013 |
Dobarro M, Orejana L, Aguirre N, RamÃrez MJ. Propranolol restores cognitive deficits and improves amyloid and Tau pathologies in a senescence-accelerated mouse model. Neuropharmacology. 64: 137-44. PMID 22824191 DOI: 10.1016/J.Neuropharm.2012.06.047 |
0.338 |
|
2012 |
MartÃnez-Turrillas R, Puerta E, Chowdhury D, Marco S, Watanabe M, Aguirre N, Pérez-Otaño I. The NMDA receptor subunit GluN3A protects against 3-nitroproprionic-induced striatal lesions via inhibition of calpain activation. Neurobiology of Disease. 48: 290-8. PMID 22801082 DOI: 10.1016/J.Nbd.2012.07.001 |
0.342 |
|
2012 |
Puerta E, Barros-Miñones L, Hervias I, Gomez-Rodriguez V, Orejana L, Pizarro N, de la Torre R, Jordán J, Aguirre N. Long-lasting neuroprotective effect of sildenafil against 3,4-methylenedioxymethamphetamine- induced 5-hydroxytryptamine deficits in the rat brain. Journal of Neuroscience Research. 90: 518-28. PMID 21948520 DOI: 10.1002/Jnr.22759 |
0.404 |
|
2012 |
Orejana L, Barros-Miñones L, Jordán J, Puerta E, Aguirre N. Sildenafil ameliorates cognitive deficits and tau pathology in a senescence-accelerated mouse model. Neurobiology of Aging. 33: 625.e11-20. PMID 21546125 DOI: 10.1016/J.Neurobiolaging.2011.03.018 |
0.333 |
|
2011 |
Cuadrado-Tejedor M, Hervias I, Ricobaraza A, Puerta E, Pérez-Roldán JM, GarcÃa-Barroso C, Franco R, Aguirre N, GarcÃa-Osta A. Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease. British Journal of Pharmacology. 164: 2029-41. PMID 21627640 DOI: 10.1111/J.1476-5381.2011.01517.X |
0.33 |
|
2011 |
Puerta E, Aguirre N. Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): Neurodegeneration versus neuromodulation Pharmaceuticals. 4: 992-1018. DOI: 10.3390/Ph4070992 |
0.354 |
|
2010 |
Perez-Alvarez S, Cuenca-Lopez MD, de Mera RM, Puerta E, Karachitos A, Bednarczyk P, Kmita H, Aguirre N, Galindo MF, Jordán J. Methadone induces necrotic-like cell death in SH-SY5Y cells by an impairment of mitochondrial ATP synthesis. Biochimica Et Biophysica Acta. 1802: 1036-47. PMID 20691259 DOI: 10.1016/J.Bbadis.2010.07.024 |
0.318 |
|
2010 |
Puerta E, Pastor F, Dvoracek J, de Saavedra MD, Goñi-Allo B, Jordán J, Hervias I, Aguirre N. Delayed pre-conditioning by 3-nitropropionic acid prevents 3,4-methylenedioxymetamphetamine-induced 5-HT deficits. Journal of Neurochemistry. 114: 843-52. PMID 20477949 DOI: 10.1111/J.1471-4159.2010.06808.X |
0.353 |
|
2010 |
Puerta E, Hervias I, Goñi-Allo B, Zhang SF, Jordán J, Starkov AA, Aguirre N. Methylenedioxymethamphetamine inhibits mitochondrial complex I activity in mice: a possible mechanism underlying neurotoxicity. British Journal of Pharmacology. 160: 233-45. PMID 20423338 DOI: 10.1111/J.1476-5381.2010.00663.X |
0.36 |
|
2010 |
Puerta E, Hervias I, Barros-Miñones L, Jordan J, Ricobaraza A, Cuadrado-Tejedor M, GarcÃa-Osta A, Aguirre N. Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF. Neurobiology of Disease. 38: 237-45. PMID 20109548 DOI: 10.1016/J.Nbd.2010.01.013 |
0.35 |
|
2010 |
Garcia-Martinez EM, Sanz-Blasco S, Karachitos A, Bandez MJ, Fernandez-Gomez FJ, Perez-Alvarez S, de Mera RM, Jordan MJ, Aguirre N, Galindo MF, Villalobos C, Navarro A, Kmita H, Jordán J. Mitochondria and calcium flux as targets of neuroprotection caused by minocycline in cerebellar granule cells. Biochemical Pharmacology. 79: 239-50. PMID 19682437 DOI: 10.1016/J.Bcp.2009.07.028 |
0.34 |
|
2009 |
Puerta E, Hervias I, Aguirre N. On the mechanisms underlying 3,4-methylenedioxymethamphetamine toxicity: the dilemma of the chicken and the egg. Neuropsychobiology. 60: 119-29. PMID 19893329 DOI: 10.1159/000253548 |
0.348 |
|
2009 |
Puerta E, Hervias I, Goñi-Allo B, Lasheras B, Jordan J, Aguirre N. Phosphodiesterase 5 inhibitors prevent 3,4-methylenedioxymethamphetamine-induced 5-HT deficits in the rat. Journal of Neurochemistry. 108: 755-66. PMID 19187094 DOI: 10.1111/J.1471-4159.2008.05825.X |
0.369 |
|
2008 |
Goñi-Allo B, Puerta E, Mathúna BO, Hervias I, Lasheras B, de la Torre R, Aguirre N. On the role of tyrosine and peripheral metabolism in 3,4-methylenedioxymethamphetamine-induced serotonin neurotoxicity in rats. Neuropharmacology. 54: 885-900. PMID 18329670 DOI: 10.1016/J.Neuropharm.2008.01.007 |
0.376 |
|
2008 |
Goni-Allo B, O Mathúna B, Segura M, Puerta E, Lasheras B, de la Torre R, Aguirre N. The relationship between core body temperature and 3,4-methylenedioxymethamphetamine metabolism in rats: implications for neurotoxicity. Psychopharmacology. 197: 263-78. PMID 18074122 DOI: 10.1007/S00213-007-1027-1 |
0.327 |
|
2008 |
Goñi-Allo B, Puerta E, Ramos M, Lasheras B, Jordán J, Aguirre N. Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK. Journal of Neurochemistry. 104: 914-25. PMID 17995929 DOI: 10.1111/J.1471-4159.2007.05042.X |
0.323 |
|
2007 |
Jordan J, Fernandez-Gomez FJ, Ramos M, Ikuta I, Aguirre N, Galindo MF. Minocycline and cytoprotection: shedding new light on a shadowy controversy. Current Drug Delivery. 4: 225-31. PMID 17627496 DOI: 10.2174/156720107781023938 |
0.303 |
|
2007 |
Goñi-Allo B, Puerta E, Hervias I, Di Palma R, Ramos M, Lasheras B, Aguirre N. Studies on the mechanisms underlying amiloride enhancement of 3,4-methylenedioxymethamphetamine-induced serotonin depletion in rats. European Journal of Pharmacology. 562: 198-207. PMID 17320075 DOI: 10.1016/J.Ejphar.2007.01.049 |
0.37 |
|
2006 |
Goñi-Allo B, Ramos M, Herv'as I, Lasheras B, Aguirre N. Studies on striatal neurotoxicity caused by the 3,4-methylenedioxymethamphetamine/ malonate combination: implications for serotonin/dopamine interactions. Journal of Psychopharmacology (Oxford, England). 20: 245-56. PMID 16510482 DOI: 10.1177/0269881106063264 |
0.362 |
|
2005 |
Fernandez-Gomez FJ, Gomez-Lazaro M, Pastor D, Calvo S, Aguirre N, Galindo MF, Jordán J. Minocycline fails to protect cerebellar granular cell cultures against malonate-induced cell death. Neurobiology of Disease. 20: 384-91. PMID 16242643 DOI: 10.1016/J.Nbd.2005.03.019 |
0.37 |
|
2005 |
Aguirre N, Beal MF, Matson WR, Bogdanov MB. Increased oxidative damage to DNA in an animal model of amyotrophic lateral sclerosis. Free Radical Research. 39: 383-8. PMID 16028363 DOI: 10.1080/10715760400027979 |
0.454 |
|
2005 |
Fernandez-Gomez FJ, Galindo MF, Gomez-Lazaro M, González-GarcÃa C, Ceña V, Aguirre N, Jordán J. Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions. Neuroscience. 133: 959-67. PMID 15964487 DOI: 10.1016/J.Neuroscience.2005.03.019 |
0.331 |
|
2005 |
Ramos M, Goñi-Allo B, Aguirre N. Ibotenic acid lesions of the medial prefrontal cortex block the development and expression of 3,4-methylenedioxymethamphetamine-induced behavioral sensitization in rats. Behavioural Brain Research. 160: 304-11. PMID 15863226 DOI: 10.1016/J.Bbr.2004.12.010 |
0.315 |
|
2005 |
Ramos M, Goñi-Allo B, Aguirre N. Administration of SCH 23390 into the medial prefrontal cortex blocks the expression of MDMA-induced behavioral sensitization in rats: an effect mediated by 5-HT2C receptor stimulation and not by D1 receptor blockade. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 2180-91. PMID 15841107 DOI: 10.1038/Sj.Npp.1300735 |
0.354 |
|
2005 |
Fernandez-Gomez FJ, Galindo MF, Gómez-Lázaro M, Yuste VJ, Comella JX, Aguirre N, Jordán J. Malonate induces cell death via mitochondrial potential collapse and delayed swelling through an ROS-dependent pathway. British Journal of Pharmacology. 144: 528-37. PMID 15655518 DOI: 10.1038/Sj.Bjp.0706069 |
0.315 |
|
2005 |
Goñi-Allo B, Ramos M, Jordán J, Aguirre N. In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-d-aspartate. Experimental Neurology. 191: 326-30. PMID 15649488 DOI: 10.1016/J.Expneurol.2004.10.010 |
0.302 |
|
2004 |
Ramos M, Goñi-Allo B, Aguirre N. Studies on the role of dopamine D1 receptors in the development and expression of MDMA-induced behavioral sensitization in rats. Psychopharmacology. 177: 100-10. PMID 15338099 DOI: 10.1007/S00213-004-1937-0 |
0.32 |
|
2003 |
Wu AS, Kiaei M, Aguirre N, Crow JP, Calingasan NY, Browne SE, Beal MF. Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis. Journal of Neurochemistry. 85: 142-50. PMID 12641736 DOI: 10.1046/J.1471-4159.2003.01639.X |
0.546 |
|
2000 |
HervÃas I, Lasheras B, Aguirre N. 2-Deoxy-D-glucose prevents and nicotinamide potentiates 3, 4-methylenedioxymethamphetamine-induced serotonin neurotoxicity. Journal of Neurochemistry. 75: 982-90. PMID 10936179 DOI: 10.1046/J.1471-4159.2000.0750982.X |
0.392 |
|
2000 |
Barrionuevo M, Aguirre N, Del RÃo JD, Lasheras B. Serotonergic deficits and impaired passive-avoidance learning in rats by MDEA: a comparison with MDMA. Pharmacology, Biochemistry, and Behavior. 65: 233-40. PMID 10672974 DOI: 10.1016/S0091-3057(99)00170-7 |
0.376 |
|
1999 |
Aguirre N, Barrionuevo M, RamÃrez MJ, Del RÃo J, Lasheras B. Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity. Neuroreport. 10: 3675-80. PMID 10619665 DOI: 10.1097/00001756-199911260-00039 |
0.388 |
|
1998 |
Aguirre N, Ballaz S, Lasheras B, Del RÃo J. MDMA ('Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion. European Journal of Pharmacology. 346: 181-8. PMID 9652358 DOI: 10.1016/S0014-2999(98)00062-4 |
0.357 |
|
1997 |
Aguirre N, Frechilla D, GarcÃa-Osta A, Lasheras B, Del RÃo J. Differential regulation by methylenedioxymethamphetamine of 5-hydroxytryptamine1A receptor density and mRNA expression in rat hippocampus, frontal cortex, and brainstem: the role of corticosteroids. Journal of Neurochemistry. 68: 1099-105. PMID 9048755 DOI: 10.1046/J.1471-4159.1997.68031099.X |
0.342 |
|
1995 |
Aguirre N, Galbete JL, Lasheras B, Del RÃo J. Methylenedioxymethamphetamine induces opposite changes in central pre- and postsynaptic 5-HT1A receptors in rats. European Journal of Pharmacology. 281: 101-5. PMID 8566108 DOI: 10.1016/0014-2999(95)00303-3 |
0.33 |
|
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