Year |
Citation |
Score |
2023 |
Singhal SM, Zell V, Faget L, Slosky LM, Barak LS, Caron MG, Pinkerton AB, Hnasko TS. Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens. Neuropharmacology. 109544. PMID 37055008 DOI: 10.1016/j.neuropharm.2023.109544 |
0.772 |
|
2023 |
Krumm BE, DiBerto JF, Olsen RHJ, Kang HJ, Slocum ST, Zhang S, Strachan RT, Huang XP, Slosky LM, Pinkerton AB, Barak LS, Caron MG, Kenakin T, Fay JF, Roth BL. Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry. PMID 36917754 DOI: 10.1021/acs.biochem.3c00029 |
0.824 |
|
2022 |
Slosky LM, Pires A, Bai Y, Clark NB, Hauser ER, Gross JD, Porkka F, Zhou Y, Chen X, Pogorelov VM, Toth K, Wetsel WC, Barak LS, Caron MG. Establishment of multi-stage intravenous self-administration paradigms in mice. Scientific Reports. 12: 21422. PMID 36503898 DOI: 10.1038/s41598-022-24740-2 |
0.712 |
|
2022 |
Hornburg KJ, Slosky LM, Cofer G, Cook J, Qi Y, Porkka F, Clark NB, Pires A, Petrella JR, White LE, Wetsel WC, Barak L, Caron MG, Johnson GA. Prenatal Heroin Exposure Alters Brain Morphology and Connectivity in Adolescent Mice. Nmr in Biomedicine. e4842. PMID 36259728 DOI: 10.1002/nbm.4842 |
0.704 |
|
2022 |
Zheng K, Smith JS, Eiger DS, Warman A, Choi I, Honeycutt CC, Boldizsar N, Gundry JN, Pack TF, Inoue A, Caron MG, Rajagopal S. Biased agonists of the chemokine receptor CXCR3 differentially signal through Gα:β-arrestin complexes. Science Signaling. 15: eabg5203. PMID 35316095 DOI: 10.1126/scisignal.abg5203 |
0.537 |
|
2021 |
Turu G, Soltész-Katona E, Tóth AD, Juhász C, Cserző M, Misák Á, Balla A, Caron MG, Hunyady L. Biased Coupling to β-Arrestin of Two Common Variants of the CB Cannabinoid Receptor. Frontiers in Endocrinology. 12: 714561. PMID 34484125 DOI: 10.3389/fendo.2021.714561 |
0.372 |
|
2021 |
Martini ML, Ray C, Yu X, Liu J, Pogorelov VM, Wetsel WC, Huang XP, McCorvy JD, Caron MG, Jin J. Addition to "Designing Functionally Selective Noncatechol Dopamine D Receptor Agonists with Potent In Vivo Antiparkinsonian Activity". Acs Chemical Neuroscience. PMID 33830725 DOI: 10.1021/acschemneuro.1c00186 |
0.305 |
|
2021 |
Slosky LM, Caron MG, Barak LS. Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery. Trends in Pharmacological Sciences. PMID 33581873 DOI: 10.1016/j.tips.2020.12.005 |
0.787 |
|
2021 |
Smith JS, Pack TF, Inoue A, Lee C, Zheng K, Choi I, Eiger DS, Warman A, Xiong X, Ma Z, Viswanathan G, Levitan IM, Rochelle LK, Staus DP, Snyder JC, ... ... Caron MG, et al. Noncanonical scaffolding of G and β-arrestin by G protein-coupled receptors. Science (New York, N.Y.). PMID 33479120 DOI: 10.1126/science.aay1833 |
0.806 |
|
2020 |
Favier M, Janickova H, Justo D, Kljakic O, Runtz L, Natsheh JY, Pascoal TA, Germann J, Gallino D, Kang JI, Meng XQ, Antinora C, Raulic S, Jacobsen JP, Moquin L, ... ... Caron MG, et al. Cholinergic dysfunction in the dorsal striatum promotes habit formation and maladaptive eating. The Journal of Clinical Investigation. PMID 33164988 DOI: 10.1172/JCI138532 |
0.558 |
|
2020 |
Slosky LM, Bai Y, Toth K, Ray C, Rochelle LK, Badea A, Chandrasekhar R, Pogorelov VM, Abraham DM, Atluri N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney P, Yuan H, ... ... Caron MG, et al. β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors. Cell. PMID 32470395 DOI: 10.1016/J.Cell.2020.04.053 |
0.77 |
|
2020 |
Zheng K, Smith JS, Choi I, Warman A, Gundry JN, Pack TF, Inoue A, Caron M, Rajagopal S. Biased agonists of the chemokine receptor CXCR3 differentially drive formation of Gαi and β‐arrestin complexes The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03543 |
0.733 |
|
2019 |
Toth K, Nagi K, Slosky LM, Rochelle L, Ray C, Kaur S, Shenoy SK, Caron MG, Barak LS. Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs. Acs Pharmacology & Translational Science. 2: 230-246. PMID 32259059 DOI: 10.1021/acsptsci.9b00018 |
0.838 |
|
2019 |
Pinkerton AB, Peddibhotla S, Yamamoto F, Slosky L, Bai Y, Maloney PR, Hershberger P, Hedrick MP, Falter B, Ardecky RJ, Smith LH, Chung TD, Jackson M, Caron MG, Barak LS. Discovery of b-Arrestin Biased, Orally Bioavailable and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31390201 DOI: 10.1021/Acs.Jmedchem.9B00340 |
0.793 |
|
2019 |
Martini ML, Ray C, Yu X, Liu J, Pogorelov V, Wetsel WC, Huang XP, McCorvy J, Caron MG, Jin J. Designing Functionally Selective Non-Catechol Dopamine D1 Receptor Agonists with Potent In Vivo Antiparkinsonian Activity. Acs Chemical Neuroscience. PMID 31387346 DOI: 10.1021/Acschemneuro.9B00410 |
0.315 |
|
2019 |
Martini ML, Liu J, Ray C, Yu X, Huang XP, Urs A, Urs NM, McCorvy J, Caron MG, Roth BL, Jin J. Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists. Journal of Medicinal Chemistry. PMID 30875219 DOI: 10.1021/Acs.Jmedchem.9B00351 |
0.337 |
|
2019 |
Beaulieu J, Borrelli E, Carlsson A, Caron MG, Civelli O, Espinoza S, Fisone G, Gainetdinov RR, Grandy DK, Kebabian JW, Langer SZ, Missale MC, Neve KA, Scatton B, Schwartz J, et al. Dopamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f20/2019.4 |
0.515 |
|
2018 |
Mackie DI, Al Mutairi F, Davis RB, Kechele DO, Nielsen NR, Snyder JC, Caron MG, Kliman HJ, Berg JS, Simms J, Poyner DR, Caron KM. h mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia. The Journal of Experimental Medicine. PMID 30115739 DOI: 10.1084/Jem.20180528 |
0.355 |
|
2017 |
Toth K, Slosky LM, Pack TF, Urs NM, Boone P, Mao L, Abraham D, Caron MG, Barak LS. Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2. Synapse (New York, N.Y.). PMID 28941296 DOI: 10.1002/Syn.22012 |
0.78 |
|
2017 |
Zhu L, Rossi M, Cui Y, Lee RJ, Sakamoto W, Perry NA, Urs NM, Caron MG, Gurevich VV, Godlewski G, Kunos G, Chen M, Chen W, Wess J. Hepatic β-arrestin 2 is essential for maintaining euglycemia. The Journal of Clinical Investigation. PMID 28650340 DOI: 10.1172/Jci92913 |
0.438 |
|
2017 |
Snyder JC, Rochelle LK, Ray C, Pack TF, Bock CB, Lubkov V, Lyerly HK, Waggoner AS, Barak LS, Caron MG. Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled Receptor-5 diminishes cell fitness. The Journal of Biological Chemistry. PMID 28275053 DOI: 10.1074/Jbc.M116.756635 |
0.302 |
|
2017 |
Le Gonidec S, Chaves-Almagro C, Bai Y, Kang HJ, Smith A, Wanecq E, Huang XP, Prats H, Knibiehler B, Roth BL, Barak LS, Caron MG, Valet P, Audigier Y, Masri B. Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28242772 DOI: 10.1096/fj.201601074R |
0.358 |
|
2016 |
Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG. Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911814 DOI: 10.1073/Pnas.1614347113 |
0.321 |
|
2016 |
Barak LS, Bai Y, Peterson S, Evron T, Urs N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Chung TD, Rodriguiz RM, Wetsel WC, Thomas JB, Hanson GR, Pinkerton AB, ... Caron MG, et al. ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse. Acs Chemical Biology. PMID 27119457 DOI: 10.1021/Acschembio.6B00291 |
0.377 |
|
2015 |
Park SM, Chen M, Schmerberg CM, Dulman RS, Rodriguiz RM, Caron MG, Jin J, Wetsel WC. Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-like Behavior in Hypoglutamatergic Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26129680 DOI: 10.1038/Npp.2015.196 |
0.472 |
|
2015 |
Urs NM, Bido S, Peterson SM, Daigle TL, Bass CE, Gainetdinov RR, Bezard E, Caron MG. Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 112: E2517-26. PMID 25918399 DOI: 10.1073/Pnas.1502740112 |
0.656 |
|
2015 |
Burczyk M, Burkhalter MD, Blätte T, Matysik S, Caron MG, Barak LS, Philipp M. Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2. Biochemistry. 54: 765-75. PMID 25555130 DOI: 10.1021/bi501061h |
0.386 |
|
2014 |
Evron T, Peterson SM, Urs NM, Bai Y, Rochelle LK, Caron MG, Barak LS. G Protein and β-arrestin signaling bias at the ghrelin receptor. The Journal of Biological Chemistry. 289: 33442-55. PMID 25261469 DOI: 10.1074/Jbc.M114.581397 |
0.312 |
|
2014 |
Daigle TL, Ferris MJ, Gainetdinov RR, Sotnikova TD, Urs NM, Jones SR, Caron MG. Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2450-62. PMID 24776686 DOI: 10.1038/Npp.2014.97 |
0.813 |
|
2014 |
Marion S, Urs NM, Peterson SM, Sotnikova TD, Beaulieu JM, Gainetdinov RR, Caron MG. Dopamine D2 receptor relies upon PPM/PP2C protein phosphatases to dephosphorylate huntingtin protein. The Journal of Biological Chemistry. 289: 11715-24. PMID 24619418 DOI: 10.1074/Jbc.M113.544312 |
0.604 |
|
2014 |
Calipari E, Ferris M, Salahpour A, Caron M, Roberts D, Jones S. Methylphenidate self-administration increases the potency and reinforcing effects of releasers through a dopamine transporter mechanism Drug and Alcohol Dependence. 140: e24-e25. DOI: 10.1016/J.Drugalcdep.2014.02.088 |
0.777 |
|
2013 |
Calipari ES, Ferris MJ, Salahpour A, Caron MG, Jones SR. Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression. Nature Communications. 4: 2720. PMID 24193139 DOI: 10.1038/Ncomms3720 |
0.783 |
|
2013 |
Jørgensen CV, Jacobsen JP, Caron MG, Klein AB, Knudsen GM, Mikkelsen JD. Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice. Neuroscience Letters. 555: 118-22. PMID 24055299 DOI: 10.1016/j.neulet.2013.08.073 |
0.35 |
|
2013 |
Min C, Zheng M, Zhang X, Caron MG, Kim KM. Novel roles for β-arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine D3 receptors. British Journal of Pharmacology. 170: 1112-29. PMID 23992580 DOI: 10.1111/bph.12357 |
0.373 |
|
2013 |
Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M. Grk5l controls heart development by limiting mTOR signaling during symmetry breaking. Cell Reports. 4: 625-32. PMID 23972986 DOI: 10.1016/J.Celrep.2013.07.036 |
0.675 |
|
2013 |
Gregory KJ, Herman EJ, Ramsey AJ, Hammond AS, Byun NE, Stauffer SR, Manka JT, Jadhav S, Bridges TM, Weaver CD, Niswender CM, Steckler T, Drinkenburg WH, Ahnaou A, Lavreysen H, ... ... Caron MG, et al. N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement. The Journal of Pharmacology and Experimental Therapeutics. 347: 438-57. PMID 23965381 DOI: 10.1124/Jpet.113.206623 |
0.78 |
|
2013 |
Barak LS, Bai Y, Snyder JC, Wang J, Chen W, Caron MG. Triphenylmethane dye activation of beta-arrestin. Biochemistry. 52: 5403-14. PMID 23865508 DOI: 10.1021/bi400217r |
0.437 |
|
2013 |
Philipp M, Evron T, Caron MG. The role of arrestins in development. Progress in Molecular Biology and Translational Science. 118: 225-42. PMID 23764056 DOI: 10.1016/B978-0-12-394440-5.00009-7 |
0.319 |
|
2013 |
Snyder JC, Rochelle LK, Lyerly HK, Caron MG, Barak LS. Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network. The Journal of Biological Chemistry. 288: 10286-97. PMID 23439653 DOI: 10.1074/jbc.M112.447540 |
0.307 |
|
2013 |
Siesser WB, Sachs BD, Ramsey AJ, Sotnikova TD, Beaulieu JM, Zhang X, Caron MG, Gainetdinov RR. Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice. Acs Chemical Neuroscience. 4: 84-8. PMID 23336047 DOI: 10.1021/cn300127h |
0.686 |
|
2013 |
Farrell MS, Pei Y, Wan Y, Yadav PN, Daigle TL, Urban DJ, Lee HM, Sciaky N, Simmons A, Nonneman RJ, Huang XP, Hufeisen SJ, Guettier JM, Moy SS, Wess J, ... Caron MG, et al. A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 854-62. PMID 23303063 DOI: 10.1038/Npp.2012.251 |
0.678 |
|
2013 |
Hara MR, Sachs BD, Caron MG, Lefkowitz RJ. Pharmacological blockade of a β(2)AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model. Cell Cycle (Georgetown, Tex.). 12: 219-24. PMID 23287463 DOI: 10.4161/cc.23368 |
0.61 |
|
2013 |
Urs NM, Daigle TL, Ting J, Caron MG. Targeting Beta-Arrestin Dependent Signaling in the Treatment of Parkinson's Disease Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 103-104. DOI: 10.1016/B978-0-12-800044-1.00090-8 |
0.651 |
|
2012 |
Daigle TL, Caron MG. Elimination of GRK2 from cholinergic neurons reduces behavioral sensitivity to muscarinic receptor activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11461-6. PMID 22895728 DOI: 10.1523/JNEUROSCI.2234-12.2012 |
0.717 |
|
2012 |
Frankowski KJ, Hedrick MP, Gosalia P, Li K, Shi S, Whipple D, Ghosh P, Prisinzano TE, Schoenen FJ, Su Y, Vasile S, Sergienko E, Gray W, Hariharan S, Milan L, ... ... Caron MG, et al. Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. Acs Chemical Neuroscience. 3: 221-236. PMID 22737280 DOI: 10.1021/Cn200128X |
0.602 |
|
2012 |
Kile BM, Walsh PL, McElligott ZA, Bucher ES, Guillot TS, Salahpour A, Caron MG, Wightman RM. Optimizing the Temporal Resolution of Fast-Scan Cyclic Voltammetry. Acs Chemical Neuroscience. 3: 285-292. PMID 22708011 DOI: 10.1021/Cn200119U |
0.777 |
|
2012 |
Revel FG, Moreau JL, Gainetdinov RR, Ferragud A, Velázquez-Sánchez C, Sotnikova TD, Morairty SR, Harmeier A, Groebke Zbinden K, Norcross RD, Bradaia A, Kilduff TS, Biemans B, Pouzet B, Caron MG, et al. Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics. Biological Psychiatry. 72: 934-42. PMID 22705041 DOI: 10.1016/J.Biopsych.2012.05.014 |
0.31 |
|
2012 |
Managò F, Espinoza S, Salahpour A, Sotnikova TD, Caron MG, Premont RT, Gainetdinov RR. The role of GRK6 in animal models of Parkinson's disease and L-DOPA treatment. Scientific Reports. 2: 301. PMID 22393477 DOI: 10.1038/Srep00301 |
0.794 |
|
2012 |
Salahpour A, Caron MG. Food for thought: the physiological relevance of ghrelin and dopamine D2 receptor heterodimerization in the regulation of appetite. Neuron. 73: 210-1. PMID 22284175 DOI: 10.1016/J.Neuron.2012.01.004 |
0.723 |
|
2012 |
Evron T, Daigle TL, Caron MG. GRK2: multiple roles beyond G protein-coupled receptor desensitization. Trends in Pharmacological Sciences. 33: 154-64. PMID 22277298 DOI: 10.1016/j.tips.2011.12.003 |
0.755 |
|
2012 |
Meck WH, Cheng RK, MacDonald CJ, Gainetdinov RR, Caron MG, Cevik MÖ. Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice. Neuropharmacology. 62: 1221-9. PMID 21296093 DOI: 10.1016/J.Neuropharm.2011.01.042 |
0.507 |
|
2012 |
Peterson SM, Urs N, Caron MG. Dopamine Receptors Primer On the Autonomic Nervous System. 67-70. DOI: 10.1016/B978-0-12-386525-0.00013-5 |
0.343 |
|
2011 |
Daigle TL, Wetsel WC, Caron MG. Opposite function of dopamine D1 and N-methyl-D-aspartate receptors in striatal cannabinoid-mediated signaling. The European Journal of Neuroscience. 34: 1378-89. PMID 22034973 DOI: 10.1111/J.1460-9568.2011.07874.X |
0.726 |
|
2011 |
Espinoza S, Salahpour A, Masri B, Sotnikova TD, Messa M, Barak LS, Caron MG, Gainetdinov RR. Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor. Molecular Pharmacology. 80: 416-25. PMID 21670104 DOI: 10.1124/Mol.111.073304 |
0.73 |
|
2011 |
Evron T, Philipp M, Lu J, Meloni AR, Burkhalter M, Chen W, Caron MG. Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling. The Journal of Biological Chemistry. 286: 27676-86. PMID 21659505 DOI: 10.1074/Jbc.M111.234666 |
0.342 |
|
2011 |
Jocoy EL, André VM, Cummings DM, Rao SP, Wu N, Ramsey AJ, Caron MG, Cepeda C, Levine MS. Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum. Frontiers in Systems Neuroscience. 5: 28. PMID 21617735 DOI: 10.3389/Fnsys.2011.00028 |
0.694 |
|
2011 |
Kotsikorou E, Madrigal KE, Hurst DP, Sharir H, Lynch DL, Heynen-Genel S, Milan LB, Chung TD, Seltzman HH, Bai Y, Caron MG, Barak L, Abood ME, Reggio PH. Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry. 50: 5633-47. PMID 21534610 DOI: 10.1021/bi200010k |
0.316 |
|
2011 |
Ramsey AJ, Milenkovic M, Oliveira AF, Escobedo-Lozoya Y, Seshadri S, Salahpour A, Sawa A, Yasuda R, Caron MG. Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 5795-800. PMID 21436042 DOI: 10.1073/Pnas.1012621108 |
0.782 |
|
2011 |
Mathurin K, Gallant MA, Germain P, Allard-Chamard H, Brisson J, Iorio-Morin C, de Brum Fernandes A, Caron MG, Laporte SA, Parent JL. An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production. The Journal of Biological Chemistry. 286: 2696-706. PMID 21112970 DOI: 10.1074/Jbc.M110.178277 |
0.574 |
|
2011 |
Urs NM, Daigle TL, Caron MG. A dopamine D1 receptor-dependent β-arrestin signaling complex potentially regulates morphine-induced psychomotor activation but not reward in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 551-8. PMID 20980993 DOI: 10.1038/Npp.2010.186 |
0.69 |
|
2010 |
Sotnikova TD, Beaulieu JM, Espinoza S, Masri B, Zhang X, Salahpour A, Barak LS, Caron MG, Gainetdinov RR. The dopamine metabolite 3-methoxytyramine is a neuromodulator. Plos One. 5: e13452. PMID 20976142 DOI: 10.1371/Journal.Pone.0013452 |
0.751 |
|
2010 |
Kenakin T, Agnati LF, Caron M, Fredholm B, Guidoli D, Kobilka B, Lefkowitz RW, Lohse M, Woods A, Fuxe K. International Workshop at the Nobel Forum, Karolinska Institutet on G protein-coupled receptors: finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached? Journal of Receptor and Signal Transduction Research. 30: 284-6. PMID 20858022 DOI: 10.3109/10799893.2010.512438 |
0.593 |
|
2010 |
Zhao P, Sharir H, Kapur A, Cowan A, Geller EB, Adler MW, Seltzman HH, Reggio PH, Heynen-Genel S, Sauer M, Chung TD, Bai Y, Chen W, Caron MG, Barak LS, et al. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Molecular Pharmacology. 78: 560-8. PMID 20826425 DOI: 10.1124/Mol.110.066746 |
0.315 |
|
2010 |
Dzirasa K, Phillips HW, Sotnikova TD, Salahpour A, Kumar S, Gainetdinov RR, Caron MG, Nicolelis MA. Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6387-97. PMID 20445065 DOI: 10.1523/Jneurosci.0764-10.2010 |
0.608 |
|
2010 |
Sotnikova TD, Beaulieu J, Espinoza S, Masri B, Zhang X, Salahpour A, Barak LS, Caron MG, Gainetdinov RR. Correction: The Dopamine Metabolite 3-Methoxytyramine Is a Neuromodulator Plos One. 5. DOI: 10.1371/Annotation/A2019934-B1Cc-4781-80Cb-9E09Fc7Ff6Dc |
0.589 |
|
2009 |
Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W. G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. The Journal of Biological Chemistry. 284: 35040-8. PMID 19801552 DOI: 10.1074/Jbc.M109.047456 |
0.846 |
|
2009 |
Kapur A, Zhao P, Sharir H, Bai Y, Caron MG, Barak LS, Abood ME. Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands. The Journal of Biological Chemistry. 284: 29817-27. PMID 19723626 DOI: 10.1074/Jbc.M109.050187 |
0.465 |
|
2009 |
Dzirasa K, Ramsey AJ, Takahashi DY, Stapleton J, Potes JM, Williams JK, Gainetdinov RR, Sameshima K, Caron MG, Nicolelis MA. Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8215-24. PMID 19553461 DOI: 10.1523/Jneurosci.1773-09.2009 |
0.664 |
|
2009 |
Caron MG, Wightman RM. "To learn, you must pay attention." Molecular insights into teachers' wisdom. Proceedings of the National Academy of Sciences of the United States of America. 106: 7267-8. PMID 19416916 DOI: 10.1073/pnas.0903306106 |
0.393 |
|
2009 |
Sotnikova TD, Caron MG, Gainetdinov RR. Trace amine-associated receptors as emerging therapeutic targets. Molecular Pharmacology. 76: 229-35. PMID 19389919 DOI: 10.1124/mol.109.055970 |
0.361 |
|
2009 |
Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/Nchembio0309-131 |
0.621 |
|
2009 |
Kocerha J, Faghihi MA, Lopez-Toledano MA, Huang J, Ramsey AJ, Caron MG, Sales N, Willoughby D, Elmen J, Hansen HF, Orum H, Kauppinen S, Kenny PJ, Wahlestedt C. MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 106: 3507-12. PMID 19196972 DOI: 10.1073/Pnas.0805854106 |
0.661 |
|
2009 |
Ghisi V, Ramsey AJ, Masri B, Gainetdinov RR, Caron MG, Salahpour A. Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter. Cellular Signalling. 21: 87-94. PMID 18929645 DOI: 10.1016/J.Cellsig.2008.09.011 |
0.806 |
|
2009 |
Beaulieu JM, Gainetdinov RR, Caron MG. Akt/GSK3 signaling in the action of psychotropic drugs. Annual Review of Pharmacology and Toxicology. 49: 327-47. PMID 18928402 DOI: 10.1146/annurev.pharmtox.011008.145634 |
0.566 |
|
2008 |
Beaulieu JM, Caron MG. Looking at lithium: molecular moods and complex behaviour. Molecular Interventions. 8: 230-41. PMID 19015387 DOI: 10.1124/mi.8.5.8 |
0.539 |
|
2008 |
Philipp M, Fralish GB, Meloni AR, Chen W, MacInnes AW, Barak LS, Caron MG. Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase. Molecular Biology of the Cell. 19: 5478-89. PMID 18815277 DOI: 10.1091/Mbc.E08-05-0448 |
0.363 |
|
2008 |
Masri B, Salahpour A, Didriksen M, Ghisi V, Beaulieu JM, Gainetdinov RR, Caron MG. Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics. Proceedings of the National Academy of Sciences of the United States of America. 105: 13656-61. PMID 18768802 DOI: 10.1073/Pnas.0803522105 |
0.753 |
|
2008 |
Barak LS, Salahpour A, Zhang X, Masri B, Sotnikova TD, Ramsey AJ, Violin JD, Lefkowitz RJ, Caron MG, Gainetdinov RR. Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor. Molecular Pharmacology. 74: 585-94. PMID 18524885 DOI: 10.1124/Mol.108.048884 |
0.827 |
|
2008 |
Salahpour A, Ramsey AJ, Medvedev IO, Kile B, Sotnikova TD, Holmstrand E, Ghisi V, Nicholls PJ, Wong L, Murphy K, Sesack SR, Wightman RM, Gainetdinov RR, Caron MG. Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 105: 4405-10. PMID 18347339 DOI: 10.1073/Pnas.0707646105 |
0.792 |
|
2008 |
Murphy KL, Zhang X, Gainetdinov RR, Beaulieu JM, Caron MG. A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression. The Journal of Biological Chemistry. 283: 13216-24. PMID 18339632 DOI: 10.1074/Jbc.M706749200 |
0.623 |
|
2008 |
Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Cools MJ, Wetsel WC, Gainetdinov RR, Caron MG. Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. Proceedings of the National Academy of Sciences of the United States of America. 105: 1333-8. PMID 18212115 DOI: 10.1073/Pnas.0711496105 |
0.471 |
|
2008 |
Beaulieu JM, Marion S, Rodriguiz RM, Medvedev IO, Sotnikova TD, Ghisi V, Wetsel WC, Lefkowitz RJ, Gainetdinov RR, Caron MG. A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell. 132: 125-36. PMID 18191226 DOI: 10.1016/J.Cell.2007.11.041 |
0.657 |
|
2008 |
Ramsey AJ, Laakso A, Cyr M, Sotnikova TD, Salahpour A, Medvedev IO, Dykstra LA, Gainetdinov RR, Caron MG. Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2701-14. PMID 18185498 DOI: 10.1038/Sj.Npp.1301663 |
0.784 |
|
2008 |
Kim KM, Caron MG. Complementary roles of the DRY motif and C-terminus tail of GPCRS for G protein coupling and beta-arrestin interaction. Biochemical and Biophysical Research Communications. 366: 42-7. PMID 18036556 DOI: 10.1016/j.bbrc.2007.11.055 |
0.39 |
|
2008 |
Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Wetsel WC, Gainetdinov RR, Caron MG. Reply to Belmaker et al.: GSK3β haploinsufficiency results in lithium-like effects in the forced-swim test Proceedings of the National Academy of Sciences of the United States of America. 105: E24. DOI: 10.1073/Pnas.0803026105 |
0.407 |
|
2008 |
Caron M, Masri B, Beaulieu J, Salahpour A, Ramsey A, Sotnikova T, Gainetdinov R. S.20.03 β-Arrestin-dependent DAD2R/Akt/GSK3β signaling: relationship to mood stabilisers and antipsychotics European Neuropsychopharmacology. 18: S184. DOI: 10.1016/S0924-977X(08)70190-1 |
0.743 |
|
2007 |
Cho EY, Cho DI, Park JH, Kurose H, Caron MG, Kim KM. Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine D3 receptor. Molecular Endocrinology (Baltimore, Md.). 21: 2242-54. PMID 17536008 DOI: 10.1210/me.2007-0202 |
0.561 |
|
2007 |
Marion S, Fralish GB, Laporte S, Caron MG, Barak LS. N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins. The Journal of Biological Chemistry. 282: 18937-44. PMID 17456469 DOI: 10.1074/jbc.M700090200 |
0.704 |
|
2007 |
Zhang J, Vinuela A, Neely MH, Hallett PJ, Grant SG, Miller GM, Isacson O, Caron MG, Yao WD. Inhibition of the dopamine D1 receptor signaling by PSD-95. The Journal of Biological Chemistry. 282: 15778-89. PMID 17369255 DOI: 10.1074/Jbc.M611485200 |
0.316 |
|
2007 |
Beaulieu JM, Gainetdinov RR, Caron MG. The Akt-GSK-3 signaling cascade in the actions of dopamine. Trends in Pharmacological Sciences. 28: 166-72. PMID 17349698 DOI: 10.1016/j.tips.2007.02.006 |
0.625 |
|
2007 |
Beaulieu JM, Tirotta E, Sotnikova TD, Masri B, Salahpour A, Gainetdinov RR, Borrelli E, Caron MG. Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 881-5. PMID 17251429 DOI: 10.1523/Jneurosci.5074-06.2007 |
0.761 |
|
2007 |
Salahpour A, Medvedev IO, Beaulieu JM, Gainetdinov RR, Caron MG. Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals. Biological Psychiatry. 61: 65-9. PMID 16712807 DOI: 10.1016/J.Biopsych.2006.03.020 |
0.7 |
|
2006 |
Cho DI, Beom S, Van Tol HH, Caron MG, Kim KM. Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors. Biochemical and Biophysical Research Communications. 350: 634-40. PMID 17022946 DOI: 10.1016/j.bbrc.2006.09.090 |
0.4 |
|
2006 |
Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice. The Journal of Biological Chemistry. 281: 32072-80. PMID 16954211 DOI: 10.1074/jbc.M606062200 |
0.532 |
|
2006 |
Prado VF, Martins-Silva C, de Castro BM, Lima RF, Barros DM, Amaral E, Ramsey AJ, Sotnikova TD, Ramirez MR, Kim HG, Rossato JI, Koenen J, Quan H, Cota VR, Moraes MF, ... ... Caron MG, et al. Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. Neuron. 51: 601-12. PMID 16950158 DOI: 10.1016/J.Neuron.2006.08.005 |
0.702 |
|
2006 |
Meloni AR, Fralish GB, Kelly P, Salahpour A, Chen JK, Wechsler-Reya RJ, Lefkowitz RJ, Caron MG. Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2. Molecular and Cellular Biology. 26: 7550-60. PMID 16908539 DOI: 10.1128/Mcb.00546-06 |
0.746 |
|
2006 |
Sotnikova TD, Beaulieu JM, Gainetdinov RR, Caron MG. Molecular biology, pharmacology and functional role of the plasma membrane dopamine transporter. Cns & Neurological Disorders Drug Targets. 5: 45-56. PMID 16613553 DOI: 10.2174/187152706784111579 |
0.504 |
|
2006 |
Zhang X, Beaulieu JM, Gainetdinov RR, Caron MG. Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2. Cellular and Molecular Life Sciences : Cmls. 63: 6-11. PMID 16378243 DOI: 10.1007/s00018-005-5417-4 |
0.439 |
|
2006 |
Marion S, Oakley RH, Kim KM, Caron MG, Barak LS. A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors. The Journal of Biological Chemistry. 281: 2932-8. PMID 16319069 DOI: 10.1074/jbc.M508074200 |
0.458 |
|
2005 |
Beaulieu JM, Caron MG. Beta-arrestin goes nuclear. Cell. 123: 755-7. PMID 16325568 DOI: 10.1016/j.cell.2005.11.010 |
0.592 |
|
2005 |
Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell. 122: 261-73. PMID 16051150 DOI: 10.1016/j.cell.2005.05.012 |
0.693 |
|
2005 |
Sotnikova TD, Beaulieu JM, Barak LS, Wetsel WC, Caron MG, Gainetdinov RR. Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. Plos Biology. 3: e271. PMID 16050778 DOI: 10.1371/Journal.Pbio.0030271 |
0.5 |
|
2005 |
Medvedev IO, Gainetdinov RR, Sotnikova TD, Bohn LM, Caron MG, Dykstra LA. Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice. Psychopharmacology. 180: 408-13. PMID 15719221 DOI: 10.1007/S00213-005-2173-Y |
0.538 |
|
2005 |
Kim KM, Gainetdinov RR, Laporte SA, Caron MG, Barak LS. G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation. The Journal of Biological Chemistry. 280: 12774-80. PMID 15687500 DOI: 10.1074/jbc.M408901200 |
0.75 |
|
2005 |
Zhang X, Gainetdinov RR, Beaulieu JM, Sotnikova TD, Burch LH, Williams RB, Schwartz DA, Krishnan KR, Caron MG. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron. 45: 11-6. PMID 15629698 DOI: 10.1016/J.Neuron.2004.12.014 |
0.431 |
|
2004 |
Wilbanks AM, Fralish GB, Kirby ML, Barak LS, Li YX, Caron MG. Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway. Science (New York, N.Y.). 306: 2264-7. PMID 15618520 DOI: 10.1126/Science.1104193 |
0.813 |
|
2004 |
Torres GE, Sweeney AL, Beaulieu JM, Shashidharan P, Caron MG. Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant. Proceedings of the National Academy of Sciences of the United States of America. 101: 15650-5. PMID 15505207 DOI: 10.1073/pnas.0308088101 |
0.51 |
|
2004 |
Sotnikova TD, Budygin EA, Jones SR, Dykstra LA, Caron MG, Gainetdinov RR. Dopamine transporter-dependent and -independent actions of trace amine beta-phenylethylamine. Journal of Neurochemistry. 91: 362-73. PMID 15447669 DOI: 10.1111/j.1471-4159.2004.02721.x |
0.713 |
|
2004 |
Zhang X, Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase-2 controls brain serotonin synthesis. Science (New York, N.Y.). 305: 217. PMID 15247473 DOI: 10.1126/science.1097540 |
0.457 |
|
2004 |
Gainetdinov RR, Premont RT, Bohn LM, Lefkowitz RJ, Caron MG. Desensitization of G protein-coupled receptors and neuronal functions. Annual Review of Neuroscience. 27: 107-44. PMID 15217328 DOI: 10.1146/Annurev.Neuro.27.070203.144206 |
0.843 |
|
2004 |
Bohn LM, Dykstra LA, Lefkowitz RJ, Caron MG, Barak LS. Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery. Molecular Pharmacology. 66: 106-12. PMID 15213301 DOI: 10.1124/Mol.66.1.106 |
0.747 |
|
2004 |
Xu M, Petraschka M, McLaughlin JP, Westenbroek RE, Caron MG, Lefkowitz RJ, Czyzyk TA, Pintar JE, Terman GW, Chavkin C. Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4576-84. PMID 15140929 DOI: 10.1523/Jneurosci.5552-03.2004 |
0.413 |
|
2004 |
Quan H, Athirakul K, Wetsel WC, Torres GE, Stevens R, Chen YT, Coffman TM, Caron MG. Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2. Molecular and Cellular Biology. 24: 4166-73. PMID 15121838 DOI: 10.1128/Mcb.24.10.4166-4173.2004 |
0.438 |
|
2004 |
Beaulieu JM, Sotnikova TD, Yao WD, Kockeritz L, Woodgett JR, Gainetdinov RR, Caron MG. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. 101: 5099-104. PMID 15044694 DOI: 10.1073/Pnas.0307921101 |
0.541 |
|
2004 |
Bohn LM, Gainetdinov RR, Caron MG. G protein-coupled receptor kinase/beta-arrestin systems and drugs of abuse: psychostimulant and opiate studies in knockout mice. Neuromolecular Medicine. 5: 41-50. PMID 15001811 DOI: 10.1385/Nmm:5:1:041 |
0.667 |
|
2004 |
Yao WD, Gainetdinov RR, Arbuckle MI, Sotnikova TD, Cyr M, Beaulieu JM, Torres GE, Grant SG, Caron MG. Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron. 41: 625-38. PMID 14980210 DOI: 10.1016/S0896-6273(04)00048-0 |
0.483 |
|
2004 |
Vroon A, Heijnen CJ, Lombardi MS, Cobelens PM, Mayor F, Caron MG, Kavelaars A. Reduced GRK2 level in T cells potentiates chemotaxis and signaling in response to CCL4 Journal of Leukocyte Biology. 75: 901-909. PMID 14761932 DOI: 10.1189/Jlb.0403136 |
0.599 |
|
2004 |
Terman GW, Jin W, Cheong YP, Lowe J, Caron MG, Lefkowitz RJ, Chavkin C. G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal. British Journal of Pharmacology. 141: 55-64. PMID 14662727 DOI: 10.1038/Sj.Bjp.0705595 |
0.477 |
|
2004 |
Marion S, Weiner DM, Caron MG. RNA Editing Induces Variation in Desensitization and Trafficking of 5-Hydroxytryptamine 2c Receptor Isoforms Journal of Biological Chemistry. 279: 2945-2954. PMID 14602721 DOI: 10.1074/jbc.M308742200 |
0.389 |
|
2004 |
McLaughlin JP, Myers LC, Zarek PE, Caron MG, Lefkowitz RJ, Czyzyk TA, Pintar JE, Chavkin C. Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance. The Journal of Biological Chemistry. 279: 1810-8. PMID 14597630 DOI: 10.1074/Jbc.M305796200 |
0.516 |
|
2004 |
Walker JK, Gainetdinov RR, Feldman DS, McFawn PK, Caron MG, Lefkowitz RJ, Premont RT, Fisher JT. G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L312-9. PMID 14565944 DOI: 10.1152/Ajplung.00255.2003 |
0.784 |
|
2004 |
Ferguson SS, Caron MG. Green fluorescent protein-tagged beta-arrestin translocation as a measure of G protein-coupled receptor activation. Methods in Molecular Biology (Clifton, N.J.). 237: 121-6. PMID 14501044 |
0.626 |
|
2003 |
Barak LS, Wilbanks AM, Caron MG. Constitutive desensitization: a new paradigm for g protein-coupled receptor regulation. Assay and Drug Development Technologies. 1: 339-46. PMID 15090199 DOI: 10.1089/15406580360545152 |
0.843 |
|
2003 |
Bohn LM, Gainetdinov RR, Sotnikova TD, Medvedev IO, Lefkowitz RJ, Dykstra LA, Caron MG. Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10265-73. PMID 14614085 |
0.722 |
|
2003 |
Johnson EC, Bohn LM, Barak LS, Birse RT, Nässel DR, Caron MG, Taghert PH. Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions. The Journal of Biological Chemistry. 278: 52172-8. PMID 14555656 DOI: 10.1074/Jbc.M306756200 |
0.723 |
|
2003 |
Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science (New York, N.Y.). 301: 1391-4. PMID 12958364 DOI: 10.1126/Science.1082808 |
0.84 |
|
2003 |
Cyr M, Beaulieu JM, Laakso A, Sotnikova TD, Yao WD, Bohn LM, Gainetdinov RR, Caron MG. Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 100: 11035-40. PMID 12958210 DOI: 10.1073/Pnas.1831768100 |
0.679 |
|
2003 |
Gainetdinov RR, Bohn LM, Sotnikova TD, Cyr M, Laakso A, Macrae AD, Torres GE, Kim KM, Lefkowitz RJ, Caron MG, Premont RT. Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice. Neuron. 38: 291-303. PMID 12718862 DOI: 10.1016/S0896-6273(03)00192-2 |
0.831 |
|
2003 |
Tohgo A, Choy EW, Gesty-Palmer D, Pierce KL, Laporte S, Oakley RH, Caron MG, Lefkowitz RJ, Luttrell LM. The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. The Journal of Biological Chemistry. 278: 6258-67. PMID 12473660 DOI: 10.1074/jbc.M212231200 |
0.849 |
|
2003 |
Loebbe S, Gilsbach R, Bruss M, Caron M, Bonisch H. 11th Meeting on Adrenergic Mechanisms: Porto, Portugal 25-27 September 2003. Noradrenaline transporter knockout-mediated regulation of serotonin receptors in mice brain. Please note that the authors were incorrectly listed in Abstract P24 (Sandra et al., 2003). The corrected text appears below in full. P24 Autonomic and Autacoid Pharmacology. 23: 335-336. DOI: 10.1111/J.1474-8673.2004.00307.X |
0.348 |
|
2002 |
Bohn LM, Lefkowitz RJ, Caron MG. Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10494-500. PMID 12451149 DOI: 10.1523/Jneurosci.22-23-10494.2002 |
0.692 |
|
2002 |
Barbosa J, Ferreira LT, Martins-Silva C, Santos MS, Torres GE, Caron MG, Gomez MV, Ferguson SS, Prado MA, Prado VF. Trafficking of the vesicular acetylcholine transporter in SN56 cells: a dynamin-sensitive step and interaction with the AP-2 adaptor complex. Journal of Neurochemistry. 82: 1221-8. PMID 12358769 DOI: 10.1046/J.1471-4159.2002.01068.X |
0.471 |
|
2002 |
Wilbanks AM, Laporte SA, Bohn LM, Barak LS, Caron MG. Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors. Biochemistry. 41: 11981-9. PMID 12356298 DOI: 10.1021/Bi020275M |
0.85 |
|
2002 |
Carneiro AM, Ingram SL, Beaulieu JM, Sweeney A, Amara SG, Thomas SM, Caron MG, Torres GE. The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7045-54. PMID 12177201 DOI: 10.1523/Jneurosci.22-16-07045.2002 |
0.53 |
|
2002 |
Naga Prasad SV, Laporte SA, Chamberlain D, Caron MG, Barak L, Rockman HA. Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex. The Journal of Cell Biology. 158: 563-75. PMID 12163475 DOI: 10.1083/Jcb.200202113 |
0.741 |
|
2002 |
Savelieva KV, Caudle WM, Findlay GS, Caron MG, Miller GW. Decreased ethanol preference and consumption in dopamine transporter female knock-out mice. Alcoholism, Clinical and Experimental Research. 26: 758-64. PMID 12068242 DOI: 10.1097/00000374-200206000-00003 |
0.658 |
|
2002 |
Claing A, Laporte SA, Caron MG, Lefkowitz RJ. Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins. Progress in Neurobiology. 66: 61-79. PMID 11900882 DOI: 10.1016/S0301-0082(01)00023-5 |
0.836 |
|
2002 |
Kim YM, Barak LS, Caron MG, Benovic JL. Regulation of arrestin-3 phosphorylation by casein kinase II. The Journal of Biological Chemistry. 277: 16837-46. PMID 11877451 DOI: 10.1074/Jbc.M201379200 |
0.593 |
|
2002 |
Laporte SA, Miller WE, Kim KM, Caron MG. beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin. The Journal of Biological Chemistry. 277: 9247-54. PMID 11777907 DOI: 10.1074/Jbc.M108490200 |
0.772 |
|
2002 |
Seachrist JL, Laporte SA, Dale LB, Babwah AV, Caron MG, Anborgh PH, Ferguson SS. Rab5 association with the angiotensin II type 1A receptor promotes Rab5 GTP binding and vesicular fusion. The Journal of Biological Chemistry. 277: 679-85. PMID 11682489 DOI: 10.1074/Jbc.M109022200 |
0.69 |
|
2001 |
Miller GW, Wang YM, Gainetdinov RR, Caron MG. Dopamine transporter and vesicular monoamine transporter knockout mice : implications for Parkinson's disease. Methods in Molecular Medicine. 62: 179-90. PMID 21318776 DOI: 10.1385/1-59259-142-6:179 |
0.477 |
|
2001 |
Gu HH, Wu X, Giros B, Caron MG, Caplan MJ, Rudnick G. The NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells. Molecular Biology of the Cell. 12: 3797-807. PMID 11739781 DOI: 10.1091/Mbc.12.12.3797 |
0.479 |
|
2001 |
Mundorf ML, Joseph JD, Austin CM, Caron MG, Wightman RM. Catecholamine release and uptake in the mouse prefrontal cortex. Journal of Neurochemistry. 79: 130-42. PMID 11595765 DOI: 10.1046/J.1471-4159.2001.00554.X |
0.428 |
|
2001 |
Gainetdinov RR, Mohn AR, Bohn LM, Caron MG. Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 98: 11047-54. PMID 11572967 DOI: 10.1073/Pnas.191353298 |
0.616 |
|
2001 |
Premont RT, Gainetdinov RR, Caron MG. Following the trace of elusive amines Proceedings of the National Academy of Sciences of the United States of America. 98: 9474-9475. PMID 11504935 DOI: 10.1073/Pnas.181356198 |
0.684 |
|
2001 |
Kim KM, Valenzano KJ, Robinson SR, Yao WD, Barak LS, Caron MG. Differential regulation of the dopamine D2 and D3 receptors by G protein-coupled receptor kinases and beta-arrestins. The Journal of Biological Chemistry. 276: 37409-14. PMID 11473130 DOI: 10.1074/jbc.M106728200 |
0.319 |
|
2001 |
Pifl C, Zezula J, Spittler A, Kattinger A, Reither H, Caron MG, Hornykiewicz O. Antiproliferative action of dopamine and norepinephrine in neuroblastoma cells expressing the human dopamine transporter. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1607-9. PMID 11427501 DOI: 10.1096/Fj.00-0738Fje |
0.679 |
|
2001 |
Torres GE, Yao WD, Mohn AR, Quan H, Kim KM, Levey AI, Staudinger J, Caron MG. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron. 30: 121-34. PMID 11343649 DOI: 10.1016/S0896-6273(01)00267-7 |
0.588 |
|
2001 |
Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*. The Journal of Biological Chemistry. 276: 19452-60. PMID 11279203 DOI: 10.1074/jbc.M101450200 |
0.475 |
|
2001 |
Naga Prasad SV, Barak LS, Rapacciuolo A, Caron MG, Rockman HA. Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by β-adrenergic receptor kinase 1: A role in receptor sequestration Journal of Biological Chemistry. 276: 18953-18959. PMID 11259422 DOI: 10.1074/Jbc.M102376200 |
0.398 |
|
2001 |
Hobson JP, Rosenfeldt HM, Barak LS, Olivera A, Poulton S, Caron MG, Milstien S, Spiegel S. Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility. Science (New York, N.Y.). 291: 1800-3. PMID 11230698 DOI: 10.1126/science.1057559 |
0.374 |
|
2001 |
Zhuang X, Oosting RS, Jones SR, Gainetdinov RR, Miller GW, Caron MG, Hen R. Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 1982-7. PMID 11172062 DOI: 10.1073/pnas.98.4.1982 |
0.584 |
|
2001 |
Shetzline MA, Curtin BM, Caron MG. Secretin receptor tyrosine phosphorylation site mutation decreases receptor internalization Gastroenterology. 120: A510. DOI: 10.1016/S0016-5085(08)82532-2 |
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Bohn LM, Gainetdinov RR, Lin FT, Lefkowitz RJ, Caron MG. Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature. 408: 720-3. PMID 11130073 DOI: 10.1038/35047086 |
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Bohn LM, Xu F, Gainetdinov RR, Caron MG. Potentiated opioid analgesia in norepinephrine transporter knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9040-5. PMID 11124980 DOI: 10.1523/Jneurosci.20-24-09040.2000 |
0.596 |
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Ciliax BJ, Nash N, Heilman C, Sunahara R, Hartney A, Tiberi M, Rye DB, Caron MG, Niznik HB, Levey AI. Dopamine D(5) receptor immunolocalization in rat and monkey brain. Synapse (New York, N.Y.). 37: 125-45. PMID 10881034 DOI: 10.1002/1098-2396(200008)37:2<125::Aid-Syn7>3.0.Co;2-7 |
0.491 |
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Spielewoy C, Gonon F, Roubert C, Fauchey V, Jaber M, Caron MG, Roques BP, Hamon M, Betancur C, Maldonado R, Giros B. Increased rewarding properties of morphine in dopamine-transporter knockout mice. The European Journal of Neuroscience. 12: 1827-37. PMID 10792459 DOI: 10.1046/J.1460-9568.2000.00063.X |
0.784 |
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2000 |
Laporte SA, Oakley RH, Holt JA, Barak LS, Caron MG. The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits. The Journal of Biological Chemistry. 275: 23120-6. PMID 10770944 DOI: 10.1074/jbc.M002581200 |
0.38 |
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2000 |
Xu F, Gainetdinov RR, Wetsel WC, Jones SR, Bohn LM, Miller GW, Wang YM, Caron MG. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nature Neuroscience. 3: 465-71. PMID 10769386 DOI: 10.1038/74839 |
0.727 |
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Oakley RH, Laporte SA, Holt JA, Caron MG, Barak LS. Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. The Journal of Biological Chemistry. 275: 17201-10. PMID 10748214 DOI: 10.1074/jbc.M910348199 |
0.434 |
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2000 |
Carman CV, Barak LS, Chen C, Liu-Chen LY, Onorato JJ, Kennedy SP, Caron MG, Benovic JL. Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 275: 10443-52. PMID 10744734 DOI: 10.1074/jbc.275.14.10443 |
0.618 |
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2000 |
Dumartin B, Jaber M, Gonon F, Caron MG, Giros B, Bloch B. Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 1879-84. PMID 10677550 DOI: 10.1073/Pnas.97.4.1879 |
0.586 |
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2000 |
Travis ER, Wang YM, Michael DJ, Caron MG, Wightman RM. Differential quantal release of histamine and 5-hydroxytryptamine from mast cells of vesicular monoamine transporter 2 knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 162-7. PMID 10618388 DOI: 10.1073/Pnas.97.1.162 |
0.39 |
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2000 |
Bliziotes M, McLoughlin S, Gunness M, Fumagalli F, Jones SR, Caron MG. Bone histomorphometric and biomechanical abnormalities in mice homozygous for deletion of the dopamine transporter gene. Bone. 26: 15-9. PMID 10617152 DOI: 10.1016/S8756-3282(99)00232-X |
0.382 |
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Shetzline MA, Walker JK, Curtin BM, Premont RT, Caron MG. The role of protein kinase a (PKA) dependent phosphorylation of the secretin receptor in receptor internalization Gastroenterology. 118: A309. DOI: 10.1016/S0016-5085(00)83325-9 |
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Shetzline MA, Walker JK, Curtin BM, Premont RT, Caron MG. G protein-coupled receptor kinase (GRK) specificity of endogenous type 1 vasoactive intestinal polvpeptide (VIP) receptor expressed on the surface of HEK 293 cells Gastroenterology. 118: A309. DOI: 10.1016/S0016-5085(00)83324-7 |
0.743 |
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1999 |
Walker JKL, Peppel K, Lefkowitz RJ, Caron MG, Fisher JT. Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 276: R1214-R1221. PMID 29592499 DOI: 10.1152/ajpregu.1999.276.4.R1214 |
0.742 |
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Barak LS, Zhang J, Ferguson SS, Laporte SA, Caron MG. Signaling, desensitization, and trafficking of G protein-coupled receptors revealed by green fluorescent protein conjugates. Methods in Enzymology. 302: 153-71. PMID 12876769 DOI: 10.1016/S0076-6879(99)02016-9 |
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Gainetdinov RR, Bohn LM, Walker JK, Laporte SA, Macrae AD, Caron MG, Lefkowitz RJ, Premont RT. Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice. Neuron. 24: 1029-36. PMID 10624964 DOI: 10.1016/S0896-6273(00)81048-X |
0.84 |
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1999 |
Bohn LM, Lefkowitz RJ, Gainetdinov RR, Peppel K, Caron MG, Lin FT. Enhanced morphine analgesia in mice lacking beta-arrestin 2. Science (New York, N.Y.). 286: 2495-8. PMID 10617462 DOI: 10.1126/Science.286.5449.2495 |
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Jones SR, Gainetdinov RR, Caron MG. Application of microdialysis and voltammetry to assess dopamine functions in genetically altered mice: correlation with locomotor activity. Psychopharmacology. 147: 30-2. PMID 10591864 DOI: 10.1007/s002130051137 |
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1999 |
Jones SR, Joseph JD, Barak LS, Caron MG, Wightman RM. Dopamine neuronal transport kinetics and effects of amphetamine. Journal of Neurochemistry. 73: 2406-14. PMID 10582600 DOI: 10.1046/J.1471-4159.1999.0732406.X |
0.542 |
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1999 |
Jaber M, Dumartin B, Sagné C, Haycock JW, Roubert C, Giros B, Bloch B, Caron MG. Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter. The European Journal of Neuroscience. 11: 3499-511. PMID 10564358 DOI: 10.1046/J.1460-9568.1999.00764.X |
0.758 |
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1999 |
Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. The Journal of Biological Chemistry. 274: 32248-57. PMID 10542263 DOI: 10.1074/jbc.274.45.32248 |
0.447 |
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1999 |
Gainetdinov RR, Caron MG. Delineating muscarinic receptor functions Proceedings of the National Academy of Sciences of the United States of America. 96: 12222-12223. PMID 10535900 DOI: 10.1073/pnas.96.22.12222 |
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Walker JK, Premont RT, Barak LS, Caron MG, Shetzline MA. Properties of secretin receptor internalization differ from those of the beta(2)-adrenergic receptor. The Journal of Biological Chemistry. 274: 31515-23. PMID 10531354 DOI: 10.1074/Jbc.274.44.31515 |
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1999 |
Miller GW, Gainetdinov RR, Levey AI, Caron MG. Dopamine transporters and neuronal injury. Trends in Pharmacological Sciences. 20: 424-9. PMID 10498956 DOI: 10.1016/S0165-6147(99)01379-6 |
0.56 |
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1999 |
Mohn AR, Gainetdinov RR, Caron MG, Koller BH. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia Cell. 98: 427-436. PMID 10481908 DOI: 10.1016/S0092-8674(00)81972-8 |
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1999 |
Gainetdinov RR, Jones SR, Caron MG. Functional hyperdopaminergia in dopamine transporter knock-out mice. Biological Psychiatry. 46: 303-11. PMID 10435196 DOI: 10.1016/S0006-3223(99)00122-5 |
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Jones SR, Gainetdinov RR, Hu XT, Cooper DC, Wightman RM, White FJ, Caron MG. Loss of autoreceptor functions in mice lacking the dopamine transporter. Nature Neuroscience. 2: 649-55. PMID 10404198 DOI: 10.1038/10204 |
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Zhang J, Barak LS, Anborgh PH, Laporte SA, Caron MG, Ferguson SS. Cellular trafficking of G protein-coupled receptor/beta-arrestin endocytic complexes. The Journal of Biological Chemistry. 274: 10999-1006. PMID 10196181 DOI: 10.1074/jbc.274.16.10999 |
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Laporte SA, Oakley RH, Zhang J, Holt JA, Ferguson SS, Caron MG, Barak LS. The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis. Proceedings of the National Academy of Sciences of the United States of America. 96: 3712-7. PMID 10097102 DOI: 10.1073/PNAS.96.7.3712 |
0.642 |
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1999 |
Fumagalli F, Gainetdinov RR, Wang YM, Valenzano KJ, Miller GW, Caron MG. Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2424-31. PMID 10087057 DOI: 10.1523/Jneurosci.19-07-02424.1999 |
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1999 |
Zhang J, Ferguson SS, Law PY, Barak LS, Caron MG. Agonist-specific regulation of delta-opioid receptor trafficking by G protein-coupled receptor kinase and beta-arrestin. Journal of Receptor and Signal Transduction Research. 19: 301-13. PMID 10071766 DOI: 10.3109/10799899909036653 |
0.589 |
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1999 |
Barak LS, Warabi K, Feng X, Caron MG, Kwatra MM. Real-time visualization of the cellular redistribution of G protein-coupled receptor kinase 2 and beta-arrestin 2 during homologous desensitization of the substance P receptor. The Journal of Biological Chemistry. 274: 7565-9. PMID 10066824 DOI: 10.1074/jbc.274.11.7565 |
0.425 |
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1999 |
Mhaouty-Kodja S, Barak LS, Scheer A, Abuin L, Diviani D, Caron MG, Cotecchia S. Constitutively active alpha-1b adrenergic receptor mutants display different phosphorylation and internalization features. Molecular Pharmacology. 55: 339-47. PMID 9927627 DOI: 10.1124/MOL.55.2.339 |
0.639 |
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1999 |
Luttrell LM, Ferguson SS, Daaka Y, Miller WE, Maudsley S, Della Rocca GJ, Lin F, Kawakatsu H, Owada K, Luttrell DK, Caron MG, Lefkowitz RJ. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science (New York, N.Y.). 283: 655-61. PMID 9924018 DOI: 10.1126/Science.283.5402.655 |
0.858 |
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1999 |
Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science (New York, N.Y.). 283: 397-401. PMID 9888856 DOI: 10.1126/Science.283.5400.397 |
0.39 |
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1998 |
Rocha BA, Fumagalli F, Gainetdinov RR, Jones SR, Ator R, Giros B, Miller GW, Caron MG. Cocaine self-administration in dopamine-transporter knockout mice. Nature Neuroscience. 1: 132-7. PMID 10195128 DOI: 10.1038/381 |
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1998 |
Cases O, Lebrand C, Giros B, Vitalis T, De Maeyer E, Caron MG, Price DJ, Gaspar P, Seif I. Plasma membrane transporters of serotonin, dopamine, and norepinephrine mediate serotonin accumulation in atypical locations in the developing brain of monoamine oxidase A knock-outs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6914-27. PMID 9712661 DOI: 10.1523/Jneurosci.18-17-06914.1998 |
0.455 |
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1998 |
Rockman HA, Choi DJ, Akhter SA, Jaber M, Giros B, Lefkowitz RJ, Caron MG, Koch WJ. Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. The Journal of Biological Chemistry. 273: 18180-4. PMID 9660778 DOI: 10.1074/Jbc.273.29.18180 |
0.79 |
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1998 |
Gainetdinov RR, Jones SR, Fumagalli F, Wightman RM, Caron MG. Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis. Brain Research. Brain Research Reviews. 26: 148-53. PMID 9651511 DOI: 10.1016/S0165-0173(97)00063-5 |
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1998 |
Zhang J, Ferguson SS, Barak LS, Bodduluri SR, Laporte SA, Law PY, Caron MG. Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness. Proceedings of the National Academy of Sciences of the United States of America. 95: 7157-62. PMID 9618555 DOI: 10.1073/PNAS.95.12.7157 |
0.56 |
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1998 |
Ferguson SS, Caron MG. G protein-coupled receptor adaptation mechanisms. Seminars in Cell & Developmental Biology. 9: 119-27. PMID 9599406 DOI: 10.1006/scdb.1997.0216 |
0.634 |
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1998 |
Ferguson SS, Zhang J, Barak LS, Caron MG. Molecular mechanisms of G protein-coupled receptor desensitization and resensitization. Life Sciences. 62: 1561-5. PMID 9585136 DOI: 10.1016/S0024-3205(98)00107-6 |
0.611 |
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1998 |
Pitcher JA, Hall RA, Daaka Y, Zhang J, Ferguson SS, Hester S, Miller S, Caron MG, Lefkowitz RJ, Barak LS. The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin. The Journal of Biological Chemistry. 273: 12316-24. PMID 9575184 DOI: 10.1074/Jbc.273.20.12316 |
0.832 |
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1998 |
Gainetdinov RR, Fumagalli F, Wang YM, Jones SR, Levey AI, Miller GW, Caron MG. Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice. Journal of Neurochemistry. 70: 1973-8. PMID 9572281 DOI: 10.1046/J.1471-4159.1998.70051973.X |
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1998 |
Feng X, Zhang J, Barak LS, Meyer T, Caron MG, Hannun YA. Visualization of dynamic trafficking of a protein kinase C betaII/green fluorescent protein conjugate reveals differences in G protein-coupled receptor activation and desensitization. The Journal of Biological Chemistry. 273: 10755-62. PMID 9553141 DOI: 10.1074/jbc.273.17.10755 |
0.372 |
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1998 |
Jones SR, Gainetdinov RR, Jaber M, Giros B, Wightman RM, Caron MG. Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 95: 4029-34. PMID 9520487 DOI: 10.1073/Pnas.95.7.4029 |
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1998 |
Shetzline MA, Premont RT, Walker JK, Vigna SR, Caron MG. A role for receptor kinases in the regulation of class II G protein-coupled receptors. Phosphorylation and desensitization of the secretin receptor. The Journal of Biological Chemistry. 273: 6756-62. PMID 9506976 DOI: 10.1074/Jbc.273.12.6756 |
0.77 |
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Jones SR, Gainetdinov RR, Wightman RM, Caron MG. Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1979-86. PMID 9482784 DOI: 10.1523/Jneurosci.18-06-01979.1998 |
0.551 |
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1998 |
Missale C, Nash SR, Robinson SW, Jaber M, Caron MG. Dopamine receptors: from structure to function. Physiological Reviews. 78: 189-225. PMID 9457173 DOI: 10.1152/PHYSREV.1998.78.1.189 |
0.359 |
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1998 |
Daaka Y, Luttrell LM, Ahn S, Della Rocca GJ, Ferguson SS, Caron MG, Lefkowitz RJ. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. The Journal of Biological Chemistry. 273: 685-8. PMID 9422717 DOI: 10.1074/Jbc.273.2.685 |
0.847 |
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1998 |
Ferguson SS, Zhang J, Barak LS, Caron MG. Role of beta-arrestins in the intracellular trafficking of G-protein-coupled receptors. Advances in Pharmacology (San Diego, Calif.). 42: 420-4. PMID 9327929 DOI: 10.1016/S1054-3589(08)60778-4 |
0.625 |
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1998 |
Fumagalli F, Jones S, Bossé R, Jaber M, Giros B, Missale C, Wightman RM, Caron MG. Inactivation of the dopamine transporter reveals essential roles of dopamine in the control of locomotion, psychostimulant response, and pituitary function. Advances in Pharmacology (San Diego, Calif.). 42: 179-82. PMID 9327873 DOI: 10.1016/S1054-3589(08)60722-X |
0.662 |
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1998 |
Rocha B, Fumagalli F, Gainetdinov R, Jones S, Ator R, Giros B, Miller G, Caron M. Erratum: Cocaine self-administration in dopamine-transporter knockout mice Nature Neuroscience. 1: 330-330. DOI: 10.1038/1152 |
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1998 |
Shetzline M, Walker J, Premont R, Vigna S, Caron M. Secretin receptor internalization involves a mechanism distinct from clathrin-coated dependent endocytosis Gastroenterology. 114: A1180. DOI: 10.1016/S0016-5085(98)84796-3 |
0.701 |
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Shetzline M, Vigna S, Caron M, Premont R. Demonstration of secretin receptor phosphorylation using a sensitive and specific receptor antisera Gastroenterology. 114: A1180. DOI: 10.1016/S0016-5085(98)84795-1 |
0.751 |
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1997 |
Wang YM, Gainetdinov RR, Fumagalli F, Xu F, Jones SR, Bock CB, Miller GW, Wightman RM, Caron MG. Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. Neuron. 19: 1285-96. PMID 9427251 DOI: 10.1016/S0896-6273(00)80419-5 |
0.646 |
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1997 |
Jaber M, Jones S, Giros B, Caron MG. The dopamine transporter: a crucial component regulating dopamine transmission. Movement Disorders : Official Journal of the Movement Disorder Society. 12: 629-33. PMID 9380041 DOI: 10.1002/Mds.870120502 |
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1997 |
Barak LS, Ferguson SS, Zhang J, Caron MG. A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation. The Journal of Biological Chemistry. 272: 27497-500. PMID 9346876 DOI: 10.1074/jbc.272.44.27497 |
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1997 |
Zhang J, Barak LS, Winkler KE, Caron MG, Ferguson SS. A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types. The Journal of Biological Chemistry. 272: 27005-14. PMID 9341139 DOI: 10.1074/jbc.272.43.27005 |
0.63 |
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1997 |
Peppel K, Boekhoff I, McDonald P, Breer H, Caron MG, Lefkowitz RJ. G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization. The Journal of Biological Chemistry. 272: 25425-8. PMID 9325250 DOI: 10.1074/jbc.272.41.25425 |
0.772 |
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1997 |
Gainetdinov RR, Fumagalli F, Jones SR, Caron MG. Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter. Journal of Neurochemistry. 69: 1322-5. PMID 9282960 DOI: 10.1046/J.1471-4159.1997.69031322.X |
0.412 |
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1997 |
Robinson SW, Caron MG. Selective inhibition of adenylyl cyclase type V by the dopamine D3 receptor. Molecular Pharmacology. 52: 508-14. PMID 9281614 DOI: 10.1124/MOL.52.3.508 |
0.354 |
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1997 |
Bossé R, Fumagalli F, Jaber M, Giros B, Gainetdinov RR, Wetsel WC, Missale C, Caron MG. Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron. 19: 127-38. PMID 9247269 DOI: 10.1016/S0896-6273(00)80353-0 |
0.513 |
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1997 |
Barak LS, Ferguson SS, Zhang J, Martenson C, Meyer T, Caron MG. Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate. Molecular Pharmacology. 51: 177-84. PMID 9203621 DOI: 10.1124/mol.51.2.177 |
0.599 |
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1997 |
Bieniasz PD, Fridell RA, Aramori I, Ferguson SS, Caron MG, Cullen BR. HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor. The Embo Journal. 16: 2599-609. PMID 9184207 DOI: 10.1093/Emboj/16.10.2599 |
0.479 |
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1997 |
Barak LS, Caron MG. Modeling of sequestration and down regulation in cells containing beta2-adrenergic receptors. Journal of Receptor and Signal Transduction Research. 15: 677-90. PMID 8903972 DOI: 10.3109/10799899509045248 |
0.465 |
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1997 |
Ferguson S, Zhang J, Barak L, Caron M. Pleiotropic Role for GRKs and b-Arrestins in Receptor Regulation Physiology. 12: 145-152. DOI: 10.1152/Physiologyonline.1997.12.4.145 |
0.487 |
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1997 |
Ménard L, Ferguson SSG, Zhang J, Lin F, Lefkowitz RJ, Caron MG, Barak LS. Synergistic Regulation of β2-Adrenergic Receptor Sequestration: Intracellular Complement of β-Adrenergic Receptor Kinase and β-Arrestin Determine Kinetics of Internalization Molecular Pharmacology. 51: 800-808. DOI: 10.1124/MOL.51.5.800 |
0.482 |
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1996 |
Jaber M, Robinson SW, Missale C, Caron MG. Dopamine receptors and brain function. Neuropharmacology. 35: 1503-19. PMID 9025098 DOI: 10.1016/S0028-3908(96)00100-1 |
0.38 |
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1996 |
Ferguson SS, Barak LS, Zhang J, Caron MG. G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins. Canadian Journal of Physiology and Pharmacology. 74: 1095-110. PMID 9022829 DOI: 10.1139/CJPP-74-10-1095 |
0.627 |
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1996 |
Ferguson SS, Zhang J, Barak LS, Caron MG. G-protein-coupled receptor kinases and arrestins: regulators of G-protein-coupled receptor sequestration. Biochemical Society Transactions. 24: 953-9. PMID 8968491 DOI: 10.1042/bst0240953 |
0.592 |
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1996 |
Jaber M, Koch WJ, Rockman H, Smith B, Bond RA, Sulik KK, Ross J, Lefkowitz RJ, Caron MG, Giros B. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. Proceedings of the National Academy of Sciences of the United States of America. 93: 12974-9. PMID 8917529 DOI: 10.1073/Pnas.93.23.12974 |
0.738 |
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1996 |
Charpentier S, Jarvie KR, Severynse DM, Caron MG, Tiberi M. Silencing of the constitutive activity of the dopamine D1B receptor. Reciprocal mutations between D1 receptor subtypes delineate residues underlying activation properties. The Journal of Biological Chemistry. 271: 28071-6. PMID 8910419 DOI: 10.1074/jbc.271.45.28071 |
0.426 |
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1996 |
Fumagalli F, Jones SR, Caron MG, Seidler FJ, Slotkin TA. Expression of mRNA coding for the serotonin transporter in aged vs. young rat brain: differential effects of glucocorticoids. Brain Research. 719: 225-8. PMID 8782886 DOI: 10.1016/0006-8993(96)00119-9 |
0.342 |
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1996 |
Zhang J, Ferguson SS, Barak LS, Ménard L, Caron MG. Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization. The Journal of Biological Chemistry. 271: 18302-5. PMID 8702465 DOI: 10.1074/jbc.271.31.18302 |
0.647 |
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1996 |
Ménard L, Ferguson SS, Barak LS, Bertrand L, Premont RT, Colapietro AM, Lefkowitz RJ, Caron MG. Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration. Biochemistry. 35: 4155-60. PMID 8672451 DOI: 10.1021/Bi952961+ |
0.819 |
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1996 |
Robinson SW, Caron MG. Chimeric D2/D3 dopamine receptors efficiently inhibit adenylyl cyclase in HEK 293 cells. Journal of Neurochemistry. 67: 212-9. PMID 8666994 DOI: 10.1046/j.1471-4159.1996.67010212.x |
0.332 |
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1996 |
Tiberi M, Nash SR, Bertrand L, Lefkowitz RJ, Caron MG. Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases. The Journal of Biological Chemistry. 271: 3771-8. PMID 8631993 DOI: 10.1074/JBC.271.7.3771 |
0.587 |
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1996 |
Giros B, Jaber M, Jones SR, Wightman RM, Caron MG. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 379: 606-12. PMID 8628395 DOI: 10.1038/379606A0 |
0.679 |
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1996 |
Ferguson SS, Downey WE, Colapietro AM, Barak LS, Ménard L, Caron MG. Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science (New York, N.Y.). 271: 363-6. PMID 8553074 DOI: 10.1126/science.271.5247.363 |
0.645 |
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1996 |
Ferguson S, Barak LS, Zhang J, Caron MG. G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins Canadian Journal of Physiology and Pharmacology. 74: 1095-1110. DOI: 10.1139/y96-124 |
0.592 |
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1995 |
Kwatra MM, Schreurs J, Schwinn DA, Innis MA, Caron MG, Lefkowitz RJ. Immunoaffinity purification of epitope-tagged human beta 2-adrenergic receptor to homogeneity. Protein Expression and Purification. 6: 717-21. PMID 8746622 DOI: 10.1006/Prep.1995.0001 |
0.724 |
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1995 |
Severynse DM, Colapietro AM, Box TL, Caron MG. The human D1A dopamine receptor gene promoter directs expression of a reporter gene to the central nervous system in transgenic mice. Brain Research. Molecular Brain Research. 30: 336-46. PMID 7637583 DOI: 10.1016/0169-328X(95)00023-L |
0.31 |
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1995 |
Freedman NJ, Liggett SB, Drachman DE, Pei G, Caron MG, Lefkowitz RJ. Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase. The Journal of Biological Chemistry. 270: 17953-61. PMID 7629102 DOI: 10.1074/Jbc.270.30.17953 |
0.815 |
|
1995 |
Kingsmore SF, Peppel K, Suh D, Caron MG, Lefkowitz RJ, Seldin MF. Genetic mapping of the beta-arrestin 1 and 2 genes on mouse chromosomes 7 and 11 respectively. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 6: 306-7. PMID 7613043 DOI: 10.1007/BF00352426 |
0.693 |
|
1995 |
Barak LS, Ménard L, Ferguson SS, Colapietro AM, Caron MG. The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor. Biochemistry. 34: 15407-14. PMID 7492540 DOI: 10.1021/BI00047A003 |
0.638 |
|
1995 |
Tiberi M, Caron MG. Constitutive Activity of Dopamine D1-Receptor Subtypes Clinical Neuropharmacology. 18: S43-S48. DOI: 10.1097/00002826-199501001-00006 |
0.313 |
|
1994 |
el Mestikawy S, Giros B, Pohl M, Hamon M, Kingsmore SF, Seldin MF, Caron MG. Characterization of an atypical member of the Na+/Cl(-)-dependent transporter family: chromosomal localization and distribution in GABAergic and glutamatergic neurons in the rat brain. Journal of Neurochemistry. 62: 445-55. PMID 8294906 DOI: 10.1046/J.1471-4159.1994.62020445.X |
0.711 |
|
1994 |
Pei G, Tiberi M, Caron MG, Lefkowitz RJ. An approach to the study of G-protein-coupled receptor kinases: An in vitro-purified membrane assay reveals differential receptor specificity and regulation by Gβγ subunits Proceedings of the National Academy of Sciences of the United States of America. 91: 3633-3636. PMID 8170959 DOI: 10.1073/Pnas.91.9.3633 |
0.676 |
|
1994 |
Scheinin M, Lomasney JW, Hayden-Hixson DM, Schambra UB, Caron MG, Lefkowitz RJ, Fremeau RT. Distribution of alpha 2-adrenergic receptor subtype gene expression in rat brain. Brain Research. Molecular Brain Research. 21: 133-49. PMID 8164514 DOI: 10.1016/0169-328X(94)90386-7 |
0.729 |
|
1994 |
Yang-Feng TL, Han H, Lomasney JW, Caron MG. Localization of the cDNA for an alpha 1-adrenergic receptor subtype (ADRA1D) to chromosome band 20p13. Cytogenetics and Cell Genetics. 66: 170-1. PMID 8125015 DOI: 10.1159/000133693 |
0.635 |
|
1994 |
Kingsmore SF, Giros B, Suh D, Bieniarz M, Caron MG, Seldin MF. Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion. Nature Genetics. 7: 136-41. PMID 7920630 DOI: 10.1038/Ng0694-136 |
0.571 |
|
1994 |
Snaprud P, Gerwins P, Caron MG, Libert F, Persson H, Fredholm BB, Fuxe K. A2a/D2 receptor interactions are not observed in COS-7 cells transiently transfected with dopamine D2 and adenosine A2a receptor cDNA. Biochemical Pharmacology. 48: 2043-7. PMID 7802693 DOI: 10.1016/0006-2952(94)90503-7 |
0.372 |
|
1994 |
Kwatra MM, Lefkowitz RJ, Caron MG. Partially Purified and Reconstituted G-Protein Coupled Receptors as Substrates of Specific Receptor Kinases Methods. 6: 11-17. DOI: 10.1006/METH.1994.1003 |
0.591 |
|
1993 |
Giros B, Caron MG. Molecular characterization of the dopamine transporter. Trends in Pharmacological Sciences. 14: 43-9. PMID 8480373 DOI: 10.1016/0165-6147(93)90029-J |
0.508 |
|
1993 |
Gingrich JA, Caron MG. Recent advances in the molecular biology of dopamine receptors. Annual Review of Neuroscience. 16: 299-321. PMID 8460895 DOI: 10.1146/annurev.ne.16.030193.001503 |
0.318 |
|
1993 |
Jarvie KR, Tiberi M, Silvia C, Gingrich JA, Caron MG. Molecular cloning, stable expression and desensitization of the human dopamine D1b/D5 receptor. Journal of Receptor Research. 13: 573-90. PMID 8450505 DOI: 10.3109/10799899309073680 |
0.347 |
|
1993 |
Pifl C, Giros B, Caron MG. Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4246-53. PMID 8410185 DOI: 10.1523/Jneurosci.13-10-04246.1993 |
0.688 |
|
1993 |
Byerley W, Coon H, Hoff M, Holik J, Waldo M, Freedman R, Caron MG, Giros B. Human dopamine transporter gene not linked to schizophrenia in multigenerational pedigrees. Human Heredity. 43: 319-22. PMID 8406521 DOI: 10.1159/000154151 |
0.468 |
|
1993 |
Duncan GE, Breese GR, Criswell HE, Johnson KB, Schambra UB, Mueller RA, Caron MG, Fremeau RT. D1 dopamine receptor binding and mRNA levels are not altered after neonatal 6-hydroxydopamine treatment: evidence against dopamine-mediated induction of D1 dopamine receptors during postnatal development. Journal of Neurochemistry. 61: 1255-62. PMID 8376983 DOI: 10.1111/J.1471-4159.1993.Tb13616.X |
0.315 |
|
1993 |
Byerley W, Hoff M, Holik J, Caron MG, Giros B. VNTR polymorphism for the human dopamine transporter gene (DAT1). Human Molecular Genetics. 2: 335. PMID 8098980 DOI: 10.1093/Hmg/2.3.335 |
0.474 |
|
1993 |
Price DT, Schwinn DA, Lomasney JW, Allen LF, Caron MG, Lefkowitz RJ. Identification, quantification, and localization of mRNA for three distinct alpha 1 adrenergic receptor subtypes in human prostate. The Journal of Urology. 150: 546-51. PMID 7686987 DOI: 10.1016/S0022-5347(17)35544-1 |
0.732 |
|
1993 |
Lefkowitz RJ, Inglese J, Koch WJ, Pitcher J, Attramadal H, Caron MG. G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins. Cold Spring Harbor Symposia On Quantitative Biology. 57: 127-33. PMID 1339651 DOI: 10.1101/Sqb.1992.057.01.016 |
0.842 |
|
1992 |
Dearry A, Falardeau P, Shores C, Caron MG. D2 dopamine receptors in the human retina: cloning of cDNA and localization of mRNA. Cellular and Molecular Neurobiology. 11: 437-53. PMID 1835903 DOI: 10.1007/BF00734808 |
0.339 |
|
1992 |
Roth NS, Lefkowitz RJ, Caron MG. Structure and function of the adrenergic receptor family. Advances in Experimental Medicine and Biology. 308: 223-38. PMID 1801586 DOI: 10.1007/978-1-4684-6015-5_20 |
0.575 |
|
1992 |
Allen LF, Lefkowitz RJ, Caron MG, Cotecchia S. G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity. Proceedings of the National Academy of Sciences of the United States of America. 88: 11354-8. PMID 1662393 DOI: 10.1073/PNAS.88.24.11354 |
0.711 |
|
1992 |
Inglese J, Koch WJ, Caron MG, Lefkowitz RJ. Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases. Nature. 359: 147-50. PMID 1522899 DOI: 10.1038/359147A0 |
0.654 |
|
1992 |
Luttrell DK, Hausdorff WP, Moyers JE, Gilmer TM, Parsons SJ, Caron MG, Lefkowitz RJ. Overexpression of pp60c-src is associated with altered regulation of adenylyl cyclase Cellular Signalling. 4: 531-541. PMID 1384635 DOI: 10.1016/0898-6568(92)90022-Z |
0.475 |
|
1992 |
Hausdorff WP, Pitcher JA, Luttrell DK, Linder ME, Kurose H, Parsons SJ, Caron MG, Lefkowitz RJ. Tyrosine phosphorylation of G protein α subunits by pp60c-src Proceedings of the National Academy of Sciences of the United States of America. 89: 5720-5724. PMID 1378615 DOI: 10.1073/Pnas.89.13.5720 |
0.788 |
|
1992 |
Gingrich JA, Dearry A, Falardeau P, Bates MD, Fremeau RT, Caron MG. Location and molecular cloning of D1 dopamine receptor. Neurochemistry International. 20: 9S-15S. PMID 1365464 DOI: 10.1016/0197-0186(92)90204-5 |
0.385 |
|
1992 |
Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ. Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms. Biochemistry. 31: 3193-7. PMID 1348186 DOI: 10.1021/Bi00127A021 |
0.787 |
|
1992 |
Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. Science (New York, N.Y.). 257: 1264-7. PMID 1325672 DOI: 10.1126/Science.1325672 |
0.811 |
|
1992 |
Ostrowski J, Kjelsberg MA, Caron MG, Lefkowitz RJ. Mutagenesis of the beta 2-adrenergic receptor: how structure elucidates function. Annual Review of Pharmacology and Toxicology. 32: 167-83. PMID 1318669 DOI: 10.1146/ANNUREV.PA.32.040192.001123 |
0.576 |
|
1992 |
Collins S, Caron MG, Lefkowitz RJ. From ligand binding to gene expression: new insights into the regulation of G-protein-coupled receptors. Trends in Biochemical Sciences. 17: 37-9. PMID 1316650 DOI: 10.1016/0968-0004(92)90425-9 |
0.729 |
|
1992 |
Giros B, El Mestikawy S, Godinot N, Yang-Feng T, Caron MG. Molecular cloning, pharmacological characterization and genetic studies of the human dopamine transporter European Neuropsychopharmacology. 2: 268-269. DOI: 10.1016/0924-977X(92)90103-F |
0.663 |
|
1991 |
Bates MD, Caron MG, Raymond JR. Desensitization of DA1 dopamine receptors coupled to adenylyl cyclase in opossum kidney cells American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 260. PMID 2058712 DOI: 10.1152/AJPRENAL.1991.260.6.F937 |
0.373 |
|
1991 |
Collins S, Caron MG, Lefkowitz RJ. Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression. Annual Review of Physiology. 53: 497-508. PMID 2042970 DOI: 10.1146/Annurev.Ph.53.030191.002433 |
0.74 |
|
1991 |
Benovic JL, Stone WC, Huebner K, Croce C, Caron MG, Lefkowitz RJ. cDNA cloning and chromosomal localization of the human α-adrenergic receptor kinase Febs Letters. 283: 122-126. PMID 2037065 DOI: 10.1016/0014-5793(91)80568-N |
0.612 |
|
1991 |
Hausdorff WP, Campbell PT, Ostrowski J, Yu SS, Caron MG, Lefkowitz RJ. A small region of the beta-adrenergic receptor is selectively involved in its rapid regulation. Proceedings of the National Academy of Sciences of the United States of America. 88: 2979-83. PMID 1849641 DOI: 10.1073/PNAS.88.8.2979 |
0.779 |
|
1991 |
Kurose H, Regan JW, Caron MG, Lefkowitz RJ. Functional interactions of recombinant alpha 2 adrenergic receptor subtypes and G proteins in reconstituted phospholipid vesicles. Biochemistry. 30: 3335-41. PMID 1849000 DOI: 10.1021/Bi00227A024 |
0.75 |
|
1991 |
Gingrich JA, Dearry A, Falardeau P, Fremeau RT, Bates MD, Caron MG. Molecular characterization of G-protein coupled receptors: isolation and cloning of a D1 dopamine receptor. Journal of Receptor Research. 11: 521-34. PMID 1832189 DOI: 10.3109/10799899109066425 |
0.375 |
|
1991 |
Tiberi M, Jarvie KR, Silvia C, Falardeau P, Gingrich JA, Godinot N, Bertrand L, Yang-Feng TL, Fremeau RT, Caron MG. Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor. Proceedings of the National Academy of Sciences of the United States of America. 88: 7491-5. PMID 1831904 DOI: 10.1073/PNAS.88.17.7491 |
0.398 |
|
1991 |
Fargin A, Yamamoto K, Cotecchia S, Goldsmith PK, Spiegel AM, Lapetina EG, Caron MG, Lefkowitz RJ. Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein. Cellular Signalling. 3: 547-57. PMID 1786205 DOI: 10.1016/0898-6568(91)90031-O |
0.728 |
|
1991 |
Giros B, el Mestikawy S, Bertrand L, Caron MG. Cloning and functional characterization of a cocaine-sensitive dopamine transporter. Febs Letters. 295: 149-54. PMID 1765147 DOI: 10.1016/0014-5793(91)81406-X |
0.682 |
|
1991 |
Oakey RJ, Caron MG, Lefkowitz RJ, Seldin MF. Genomic organization of adrenergic and serotonin receptors in the mouse: linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution. Genomics. 10: 338-44. PMID 1676978 DOI: 10.1016/0888-7543(91)90317-8 |
0.424 |
|
1991 |
Collins S, Lohse MJ, O'Dowd B, Caron MG, Lefkowitz RJ. Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model. Vitamins and Hormones. 46: 1-39. PMID 1660639 DOI: 10.1016/S0083-6729(08)60681-0 |
0.812 |
|
1991 |
Lomasney JW, Cotecchia S, Lefkowitz RJ, Caron MG. Molecular biology of alpha-adrenergic receptors: implications for receptor classification and for structure-function relationships. Biochimica Et Biophysica Acta. 1095: 127-39. PMID 1657194 DOI: 10.1016/0167-4889(91)90075-9 |
0.805 |
|
1991 |
Lorenz W, Inglese J, Palczewski K, Onorato JJ, Caron MG, Lefkowitz RJ. The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase. Proceedings of the National Academy of Sciences of the United States of America. 88: 8715-9. PMID 1656454 DOI: 10.1073/Pnas.88.19.8715 |
0.568 |
|
1991 |
Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ. Model systems for the study of seven-transmembrane-segment receptors. Annual Review of Biochemistry. 60: 653-88. PMID 1652922 DOI: 10.1146/annurev.bi.60.070191.003253 |
0.659 |
|
1991 |
Yang SD, Benovic JL, Fong YL, Caron MG, Lefkowitz RJ. Cyclic phosphorylation-dephosphorylation of rhodopsin in retina by protein kinase FA (the activator of ATP.Mg-dependent protein phosphatase) Biochemical and Biophysical Research Communications. 178: 1306-1311. PMID 1651717 DOI: 10.1016/0006-291X(91)91036-C |
0.571 |
|
1991 |
Roth NS, Campbell PT, Caron MG, Lefkowitz RJ, Lohse MJ. Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 88: 6201-4. PMID 1648731 DOI: 10.1073/Pnas.88.14.6201 |
0.581 |
|
1991 |
Onorato JJ, Palczewski K, Regan JW, Caron MG, Lefkowitz RJ, Benovic JL. Role of acidic amino acids in peptide substrates of the β-adrenergic receptor kinase and rhodopsin kinase Biochemistry®. 30: 5118-5125. PMID 1645191 DOI: 10.1021/Bi00235A002 |
0.7 |
|
1991 |
Schwinn D, Page S, Cotecchia S, Caron M, Lefkowitz R. THE α1-ADRENERGIC RECEPTOR SUBTYPE COUPLES TO PHOSPHOLIPASE C Anesthesiology. 75: A629-A629. DOI: 10.1097/00000542-199109001-00628 |
0.759 |
|
1990 |
Andersen PH, Gingrich JA, Bates MD, Dearry A, Falardeau P, Senogles SE, Caron MG. Dopamine receptor subtypes: beyond the D1/D2 classification. Trends in Pharmacological Sciences. 11: 231-6. PMID 2200181 DOI: 10.1016/0165-6147(90)90249-8 |
0.346 |
|
1990 |
Lefkowitz RJ, Hausdorff WP, Caron MG. Role of phosphorylation in desensitization of the beta-adrenoceptor. Trends in Pharmacological Sciences. 11: 190-4. PMID 2188401 DOI: 10.1016/0165-6147(90)90113-M |
0.578 |
|
1990 |
Collins S, Bouvier M, Lohse MJ, Benovic JL, Caron MG, Lefkowitz RJ. Mechanisms involved in adrenergic receptor desensitization. Biochemical Society Transactions. 18: 541-4. PMID 2177406 DOI: 10.1042/Bst0180541 |
0.828 |
|
1990 |
Benovic JL, Onorato J, Lohse MJ, Dohlman HG, Staniszewski C, Caron MG, Lefkowitz RJ. Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase. British Journal of Clinical Pharmacology. 30: 3S-12S. PMID 2176526 DOI: 10.1111/J.1365-2125.1990.Tb05462.X |
0.758 |
|
1990 |
King K, Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ. Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit. Science (New York, N.Y.). 250: 121-3. PMID 2171146 DOI: 10.1126/Science.2171146 |
0.842 |
|
1990 |
Lomasney JW, Lorenz W, Allen LF, Klng K, Regan JW, Yang-Fengh TL, Caron MG, Lefkowitz RJ. Expansion of the α2-adrenergic receptor family: Cloning and characterization of a human α2-adrenergic receptor subtype, the gene for which is located on chromosome 2 Proceedings of the National Academy of Sciences of the United States of America. 87: 5094-5098. PMID 2164221 DOI: 10.1073/Pnas.87.13.5094 |
0.79 |
|
1990 |
Valiquette M, Bonin H, Hnatowich M, Caron MG, Lefkowitz RJ, Bouvier M. Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor. Proceedings of the National Academy of Sciences of the United States of America. 87: 5089-93. PMID 2164220 DOI: 10.1073/Pnas.87.13.5089 |
0.858 |
|
1990 |
Lohse MJ, Benovic JL, Codina J, Caron MG, Lefkowitz RJ. beta-Arrestin: a protein that regulates beta-adrenergic receptor function. Science (New York, N.Y.). 248: 1547-50. PMID 2163110 DOI: 10.1126/Science.2163110 |
0.689 |
|
1990 |
Dohlman HG, Caron MG, DeBlasi A, Frielle T, Lefkowitz RJ. Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptor. Biochemistry. 29: 2335-42. PMID 2159799 DOI: 10.1021/Bi00461A018 |
0.819 |
|
1990 |
Cotecchia S, Exum S, Caron MG, Lefkowitz RJ. Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function. Proceedings of the National Academy of Sciences of the United States of America. 87: 2896-900. PMID 2158097 DOI: 10.1073/PNAS.87.8.2896 |
0.729 |
|
1990 |
Yang-Feng TL, Xue F, Zhong W, Cotecchia S, Frielle T, Caron MG, Lefkowitz RJ, Francke U. Chromosomal organization of adrenergic receptor genes Proceedings of the National Academy of Sciences of the United States of America. 87: 1516-1520. PMID 2154750 DOI: 10.1073/Pnas.87.4.1516 |
0.814 |
|
1990 |
Dearry A, Gingrich JA, Falardeau P, Fremeau RT, Bates MD, Caron MG. Molecular cloning and expression of the gene for a human D1 dopamine receptor. Nature. 347: 72-6. PMID 2144334 DOI: 10.1038/347072a0 |
0.375 |
|
1990 |
Bates MD, Gingrich JA, Bunzow JR, Falardeau P, Dearry A, Senogles SE, Civelli O, Caron MG. Molecular characterization of dopamine receptors. American Journal of Hypertension. 3: 29S-33S. PMID 2143386 DOI: 10.1093/Ajh/3.6.29S |
0.361 |
|
1990 |
Raymond JR, Hnatowich M, Lefkowitz RJ, Caron MG. Adrenergic receptors. Models for regulation of signal transduction processes. Hypertension (Dallas, Tex. : 1979). 15: 119-31. PMID 2105909 DOI: 10.1161/01.HYP.15.2.119 |
0.587 |
|
1990 |
Seuwen K, Magnaldo I, Kobilka BK, Caron MG, Regan JW, Lefkowitz RJ, Pouysségur J. Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene. Cell Regulation. 1: 445-51. PMID 1981685 DOI: 10.1091/Mbc.1.6.445 |
0.732 |
|
1990 |
Schwinn DA, Cotecchia S, Lomasney J, Caron M, Lefkowitz RJ. MOLECULAR CLONING AND EXPRESSION OF A NEW ALPHA-1-ADRENERGIC RECEPTOR SUBTYPE Anesthesia & Analgesia. 70: S359. DOI: 10.1213/00000539-199002001-00359 |
0.818 |
|
1990 |
Hausdorff WP, Caron MG, Lefkowitz RJ. Turning off the signal: desensitization of β‐adrenergic receptor function The Faseb Journal. 4: 2881-2889. DOI: 10.1096/fasebj.4.11.2165947 |
0.58 |
|
1990 |
COTECCHIA S, CARON M, LEFKOWITZ R. The molecular basis of adrenergic receptor function Cell Biology International Reports. 14: 34. DOI: 10.1016/0309-1651(90)90244-S |
0.715 |
|
1989 |
Frielle T, Daniel KW, Caron MG, Lefkowitz RJ. Structural basis of beta-adrenergic receptor subtype specificity studied with chimeric beta 1/beta 2-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 85: 9494-8. PMID 2849109 DOI: 10.1073/PNAS.85.24.9494 |
0.825 |
|
1989 |
Kwatra MM, Benovic JL, Caron MG, Lefkowitz RJ, Hosey MM. Phosphorylation of chick heart muscarinic cholinergic receptors by the β-adrenergic receptor kinase Biochemistry. 28: 4543-4547. PMID 2765501 DOI: 10.1021/Bi00437A005 |
0.673 |
|
1989 |
O'Dowd BF, Lefkowitz RJ, Caron MG. Structure of the adrenergic and related receptors. Annual Review of Neuroscience. 12: 67-83. PMID 2648960 DOI: 10.1146/ANNUREV.NE.12.030189.000435 |
0.572 |
|
1989 |
Liggett SB, Bouvier M, O'Dowd BF, Caron MG, Lefkowitz RJ, DeBlasi A. Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization. Biochemical and Biophysical Research Communications. 165: 257-63. PMID 2556136 DOI: 10.1016/0006-291X(89)91063-2 |
0.834 |
|
1989 |
Benovic JL, DeBlasi A, Stone WC, Caron MG, Lefkowitz RJ. Β-adrenergic receptor kinase: Primary structure delineates a multigene family Science. 246: 235-240. PMID 2552582 DOI: 10.1126/Science.2552582 |
0.677 |
|
1989 |
Lefkowitz RJ, Kobilka BK, Caron MG. The new biology of drug receptors. Biochemical Pharmacology. 38: 2941-8. PMID 2551299 DOI: 10.1016/0006-2952(89)90001-4 |
0.604 |
|
1989 |
Matsui H, Lefkowitz RJ, Caron MG, Regan JW. Localization of the fourth membrane spanning domain as a ligand binding site in the human platelet α2-adrenergic receptor Biochemistry. 28: 4125-4130. PMID 2546589 DOI: 10.1021/Bi00435A075 |
0.772 |
|
1989 |
Palacios JM, O'Dowd BF, Cotecchia S, Hnatowich M, Caron MG, Lefkowitz RJ. Adrenergic receptor homologies in vertebrate and invertebrate species examined by DNA hybridization. Life Sciences. 44: 2057-65. PMID 2545987 DOI: 10.1016/0024-3205(89)90352-4 |
0.827 |
|
1989 |
Lohse MJ, Lefkowitz RJ, Caron MG, Benovic JL. Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 86: 3011-5. PMID 2541428 DOI: 10.1073/Pnas.86.9.3011 |
0.666 |
|
1989 |
Collins S, Bolanowski MA, Caron MG, Lefkowitz RJ. Genetic regulation of beta-adrenergic receptors. Annual Review of Physiology. 51: 203-15. PMID 2540696 DOI: 10.1146/Annurev.Ph.51.030189.001223 |
0.85 |
|
1989 |
Collins S, Bouvier M, Bolanowski MA, Caron MG, Lefkowitz RJ. cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure. Proceedings of the National Academy of Sciences of the United States of America. 86: 4853-7. PMID 2472635 DOI: 10.1073/Pnas.86.13.4853 |
0.822 |
|
1989 |
Frielle T, Kobilka B, Lefkowitz RJ, Caron MG. Human beta 1- and beta 2-adrenergic receptors: structurally and functionally related receptors derived from distinct genes. Trends in Neurosciences. 11: 321-4. PMID 2465637 DOI: 10.1016/0166-2236(88)90095-1 |
0.848 |
|
1989 |
Frielle T, Caron MG, Lefkowitz RJ. Properties of the beta 1- and beta 2-adrenergic receptor subtypes revealed by molecular cloning. Clinical Chemistry. 35: 721-725. DOI: 10.1093/CLINCHEM/35.5.721 |
0.828 |
|
1989 |
Matsui H, Lefkowitz RJ, Caron MG, Regan JW. Localization of the fourth membrane spanning domain as a ligand binding site in the human platelet .alpha.2-adrenergic receptor [Erratum to document cited in CA110(21):187980z] Biochemistry. 28: 5702-5702. DOI: 10.1021/Bi00439A054 |
0.743 |
|
1988 |
Gingrich JA, Amlaiky N, Senogles SE, Chang WK, McQuade RD, Berger JG, Caron MG. Affinity chromatography of the D1 dopamine receptor from rat corpus striatum. Biochemistry. 27: 3907-12. PMID 3415962 DOI: 10.1021/Bi00411A003 |
0.377 |
|
1988 |
Agui T, Amlaiky N, Caron MG, Kebabian JW. Agonist-induced desensitization of the D-2 dopamine receptor in the intermediate lobe of the rat pituitary gland. Journal of Biochemistry. 103: 436-41. PMID 3391998 DOI: 10.1093/OXFORDJOURNALS.JBCHEM.A122288 |
0.318 |
|
1988 |
Fargin A, Raymond JR, Lohse MJ, Kobilka BK, Caron MG, Lefkowitz RJ. The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor. Nature. 335: 358-60. PMID 3138543 DOI: 10.1038/335358A0 |
0.704 |
|
1988 |
McQuade RD, Chipkin R, Amlaiky N, Caron M, Iorio L, Barnett A. Characterization of the radioiodinated analogue of SCH 23390: in vitro and in vivo D-1 dopamine receptor binding studies. Life Sciences. 43: 1151-1160. PMID 3050344 DOI: 10.1016/0024-3205(88)90474-2 |
0.382 |
|
1988 |
Senogles SE, Amlaiky N, Berger JG, Caron MG. Biochemical properties of D1 and D2 dopamine receptors. Advances in Experimental Medicine and Biology. 235: 33-41. PMID 2976252 |
0.376 |
|
1988 |
Lefkowitz RJ, Kobilka BK, Benovic JL, Bouvier M, Cotecchia S, Hausdorff WP, Dohlman HG, Regan JW, Caron MG. Molecular biology of adrenergic receptors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 507-14. PMID 2855490 DOI: 10.1101/Sqb.1988.053.01.058 |
0.834 |
|
1988 |
Benovic JL, Bouvier M, Caron MG, Lefkowitz RJ. Regulation of adenylyl cyclase-coupled beta-adrenergic receptors. Annual Review of Cell Biology. 4: 405-28. PMID 2848553 DOI: 10.1146/Annurev.Cb.04.110188.002201 |
0.765 |
|
1988 |
Cotecchia S, Schwinn DA, Randall RR, Lefkowitz RJ, Caron MG, Kobilka BK. Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 7159-63. PMID 2845398 DOI: 10.1073/Pnas.85.19.7159 |
0.812 |
|
1988 |
Strasser RH, Benovic JL, Lefkowitz RJ, Caron MG. The beta-adrenergic receptor kinase: role in homologous desensitization in S49 lymphoma cells Advances in Experimental Medicine and Biology. 231: 503-517. PMID 2843012 DOI: 10.1007/978-1-4684-9042-8_43 |
0.746 |
|
1988 |
Regan JW, Kobilka TS, Yang-Feng TL, Caron MG, Lefkowitz RJ, Kobilka BK. Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. Proceedings of the National Academy of Sciences of the United States of America. 85: 6301-5. PMID 2842764 DOI: 10.1073/Pnas.85.17.6301 |
0.741 |
|
1988 |
Caron MG, Kobilka BK, Frielle T, Bolanowski MA, Benovic JL, Lefkowitz RJ. Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors. Journal of Receptor Research. 8: 7-21. PMID 2838630 DOI: 10.3109/10799898809048975 |
0.847 |
|
1988 |
Collins S, Quarmby VE, French FS, Lefkowitz RJ, Caron MG. Regulation of the beta 2-adrenergic receptor and its mRNA in the rat ventral prostate by testosterone. Febs Letters. 233: 173-6. PMID 2838324 DOI: 10.1016/0014-5793(88)81378-4 |
0.678 |
|
1988 |
Dohlman HG, Caron MG, Strader CD, Amlaiky N, Lefkowitz RJ. Identification and sequence of a binding site peptide of the beta 2-adrenergic receptor. Biochemistry. 27: 1813-7. PMID 2837273 DOI: 10.1021/Bi00406A002 |
0.727 |
|
1988 |
Kobilka BK, Kobilka TS, Daniel K, Regan JW, Caron MG, Lefkowitz RJ. Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity. Science (New York, N.Y.). 240: 1310-6. PMID 2836950 DOI: 10.1126/Science.2836950 |
0.78 |
|
1988 |
Bouvier M, Hausdorff WP, De Blasi A, O'Dowd BF, Kobilka BK, Caron MG, Lefkowitz RJ. Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization. Nature. 333: 370-3. PMID 2836733 DOI: 10.1038/333370A0 |
0.759 |
|
1988 |
Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways. Endocrine Reviews. 9: 38-56. PMID 2836188 DOI: 10.1210/Edrv-9-1-38 |
0.754 |
|
1988 |
Dohlman HG, Caron MG, Strader CD, Amlaiky N, Lefkowitz RJ. Identification and sequence of a binding site peptide of the .beta.2-adrenergic receptor [Erratum to document cited in CA108(15):126956h] Biochemistry. 27: 8508-8508. DOI: 10.1021/Bi00422A034 |
0.667 |
|
1987 |
Kobilka BK, Frielle T, Collins S, Yang-Feng T, Kobilka TS, Francke U, Lefkowitz RJ, Caron MG. An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins. Nature. 329: 75-9. PMID 3041227 DOI: 10.1038/329075A0 |
0.853 |
|
1987 |
Dohlman HG, Caron MG, Lefkowitz RJ. A family of receptors coupled to guanine nucleotide regulatory proteins. Biochemistry. 26: 2657-64. PMID 3038163 DOI: 10.1021/Bi00384A001 |
0.687 |
|
1987 |
Yoshimasa T, Sibley DR, Bouvier M, Lefkowitz RJ, Caron MG. Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation. Nature. 327: 67-70. PMID 3033513 DOI: 10.1038/327067A0 |
0.783 |
|
1987 |
Cerione RA, Gierschik P, Staniszewski C, Benovic JL, Codina J, Somers R, Birnbaumer L, Spiegel AM, Lefkowitz RJ, Caron MG. Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein. Biochemistry. 26: 1485-91. PMID 3032251 DOI: 10.1021/Bi00379A041 |
0.689 |
|
1987 |
Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Regulation of transmembrane signaling by receptor phosphorylation. Cell. 48: 913-22. PMID 3030559 DOI: 10.1016/0092-8674(87)90700-8 |
0.776 |
|
1987 |
Kobilka BK, Dixon RA, Frielle T, Dohlman HG, Bolanowski MA, Sigal IS, Yang-Feng TL, Francke U, Caron MG, Lefkowitz RJ. cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. Proceedings of the National Academy of Sciences of the United States of America. 84: 46-50. PMID 3025863 DOI: 10.1073/Pnas.84.1.46 |
0.834 |
|
1987 |
Lefkowitz RJ, Caron MG. Regulation of adrenergic receptor function by phosphorylation. Current Topics in Cellular Regulation. 28: 209-31. PMID 3024910 DOI: 10.1016/B978-0-12-152828-7.50007-X |
0.593 |
|
1987 |
Benovic JL, Staniszewski C, Cerione RA, Codina J, Lefkowitz RJ, Caron MG. The mammalian βadrenergic receptor: Structural and functional characterization of the carbohydrate moiety Journal of Receptors and Signal Transduction. 7: 257-281. PMID 2887651 DOI: 10.3109/10799898709054989 |
0.747 |
|
1987 |
Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Molecular mechanisms of beta-adrenergic receptor desensitization. Advances in Experimental Medicine and Biology. 221: 253-73. PMID 2829583 DOI: 10.1007/978-1-4684-7618-7_19 |
0.78 |
|
1987 |
Benovic JL, Kühn H, Weyand I, Codina J, Caron MG, Lefkowitz RJ. Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein) Proceedings of the National Academy of Sciences of the United States of America. 84: 8879-8882. PMID 2827157 DOI: 10.1073/Pnas.84.24.8879 |
0.708 |
|
1987 |
Frielle T, Collins S, Daniel KW, Caron MG, Lefkowitz RJ, Kobilka BK. Cloning of the cDNA for the human beta 1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 84: 7920-4. PMID 2825170 DOI: 10.1073/Pnas.84.22.7920 |
0.828 |
|
1987 |
Kobilka BK, Matsui H, Kobilka TS, Yang-Feng TL, Francke U, Caron MG, Lefkowitz RJ, Regan JW. Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. Science (New York, N.Y.). 238: 650-6. PMID 2823383 DOI: 10.1126/Science.2823383 |
0.828 |
|
1987 |
Lefkowitz RJ, Caron MG. Molecular and regulatory properties of adrenergic receptors. Recent Progress in Hormone Research. 43: 469-97. PMID 2819998 DOI: 10.1016/B978-0-12-571143-2.50018-6 |
0.569 |
|
1986 |
Lefkowitz RJ, Caron MG. Ciba-Geigy award for outstanding research. Regulation of adrenergic receptor function by phosphorylation. Journal of Molecular and Cellular Cardiology. 18: 885-95. PMID 3023644 DOI: 10.1016/S0022-2828(86)80003-7 |
0.571 |
|
1986 |
Strasser RH, Benovic JL, Caron MG, Lefkowitz RJ. β-Agonist- and prostaglandin E1-induced translocation of the β-adrenergic receptor kinase: Evidence that the kinase may act on multiple adenylate cyclase-coupled receptors Proceedings of the National Academy of Sciences of the United States of America. 83: 6362-6366. PMID 3018728 DOI: 10.1073/Pnas.83.17.6362 |
0.738 |
|
1986 |
Benovic JL, Mayor F, Somers RL, Caron MG, Lefkowitz RJ. Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase Nature. 321: 869-872. PMID 3014340 DOI: 10.1038/321869A0 |
0.752 |
|
1986 |
Dixon RA, Kobilka BK, Strader DJ, Benovic JL, Dohlman HG, Frielle T, Bolanowski MA, Bennett CD, Rands E, Diehl RE, Mumford RA, Slater EE, Sigal IS, Caron MG, Lefkowitz RJ, et al. Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. Nature. 321: 75-9. PMID 3010132 DOI: 10.1038/321075A0 |
0.846 |
|
1986 |
Dickinson KE, Leeb-Lundberg LM, Strasser RH, Caron MG, Lefkowitz RJ. Identification of the subunit structure of rat pineal adrenergic receptors by photoaffinity labeling. Journal of Neurochemistry. 46: 1153-60. PMID 3005506 DOI: 10.1111/j.1471-4159.1986.tb00630.x |
0.789 |
|
1986 |
Cotecchia S, Leeb-Lundberg LM, Hagen PO, Lefkowitz RJ, Caron MG. Phorbol ester effects on alpha 1-adrenoceptor binding and phosphatidylinositol metabolism in cultured vascular smooth muscle cells. Life Sciences. 37: 2389-98. PMID 3001461 DOI: 10.1016/0024-3205(85)90106-7 |
0.777 |
|
1986 |
Senogles SE, Amlaiky N, Johnson AL, Caron MG. Affinity chromatography of the anterior pituitary D2-dopamine receptor Biochemistry. 25: 749-753. PMID 2938619 |
0.359 |
|
1986 |
Benovic JL, Strasser RH, Caron MG, Lefkowitz RJ. β-Adrenergic receptor kinase: Identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor Proceedings of the National Academy of Sciences of the United States of America. 83: 2797-2801. PMID 2871555 DOI: 10.1073/Pnas.83.9.2797 |
0.733 |
|
1986 |
Lefkowitz RJ, Benovic JL, Kobilka B, Caron MG. β-Adrenergic receptors and rhodopsin: shedding new light on an old subject Trends in Pharmacological Sciences. 7: 444-448. DOI: 10.1016/0165-6147(86)90417-7 |
0.734 |
|
1985 |
Cerione RA, Codina J, Kilpatrick BF, Staniszewski C, Gierschik P, Somers RL, Spiegel AM, Birnbaumer L, Caron MG, Lefkowitz RJ. Transducin and the inhibitory nucleotide regulatory protein inhibit the stimulatory nucleotide regulatory protein mediated stimulation of adenylate cyclase in phospholipid vesicle systems. Biochemistry. 24: 4499-503. PMID 3933556 DOI: 10.1021/Bi00338A002 |
0.563 |
|
1985 |
Cerione RA, Staniszewski C, Caron MG, Lefkowitz RJ, Codina J, Birnbaumer L. A role for Ni in the hormonal stimulation of adenylate cyclase. Nature. 318: 293-5. PMID 2999605 DOI: 10.1038/318293a0 |
0.668 |
|
1985 |
Birnbaumer L, Codina J, Mattera R, Cerione RA, Hildebrandt JD, Sunyer T, Rojas FJ, Caron MG, Lefkowitz RJ, Iyengar R. Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins. Recent Progress in Hormone Research. 41: 41-99. PMID 2996090 DOI: 10.1016/B978-0-12-571141-8.50006-8 |
0.682 |
|
1985 |
Leeb-Lundberg LM, Cotecchia S, Lomasney JW, DeBernardis JF, Lefkowitz RJ, Caron MG. Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism. Proceedings of the National Academy of Sciences of the United States of America. 82: 5651-5. PMID 2994039 DOI: 10.1073/PNAS.82.17.5651 |
0.836 |
|
1985 |
Lefkowitz RJ, Cerione RA, Codina J, Birnbaumer L, Caron MG. Reconstitution of the beta-adrenergic receptor. The Journal of Membrane Biology. 87: 1-12. PMID 2865370 DOI: 10.1007/BF01870694 |
0.688 |
|
1984 |
Kilpatrick BF, Caron MG. Dopamine receptor of the porcine anterior pituitary gland. Solubilization and characterization. Biochemical Pharmacology. 33: 1981-8. PMID 6547344 DOI: 10.1016/0006-2952(84)90559-8 |
0.354 |
|
1984 |
McDonald WM, Sibley DR, Kilpatrick BF, Caron MG. Dopaminergic inhibition of adenylate cyclase correlates with high affinity agonist binding to anterior pituitary D2 dopamine receptors. Molecular and Cellular Endocrinology. 36: 201-9. PMID 6540722 DOI: 10.1016/0303-7207(84)90037-6 |
0.568 |
|
1984 |
DeMarinis RM, Krog AJ, Shah DH, Lafferty J, Holden KG, Hieble JP, Matthews WD, Regan JW, Lefkowitz RJ, Caron MG. Development of an affinity ligand for purification of α2-adrenoceptors from human platelet membranes Journal of Medicinal Chemistry. 27: 918-921. PMID 6330361 DOI: 10.1002/Chin.198448242 |
0.615 |
|
1984 |
Heinsimer JA, Davies AO, Downs RW, Levine MA, Spiegel AM, Drezner MK, De Lean A, Wreggett KA, Caron MG, Lefkowitz RJ. Impaired formation of beta-adrenergic receptor-nucleotide regulatory protein complexes in pseudohypoparathyroidism. The Journal of Clinical Investigation. 73: 1335-43. PMID 6325502 DOI: 10.1172/Jci111336 |
0.481 |
|
1984 |
Sibley DR, Peters JR, Nambi P, Caron MG, Lefkowitz RJ. Photoaffinity labeling of turkey erythrocyte beta-adrenergic receptors: degradation of the Mr = 49,000 protein explains apparent heterogeneity. Biochemical and Biophysical Research Communications. 119: 458-64. PMID 6324763 DOI: 10.1016/S0006-291X(84)80271-5 |
0.745 |
|
1984 |
Cerione RA, Codina J, Benovic JL, Lefkowitz RJ, Birnbaumer L, Caron MG. The mammalian β2-adrenergic receptor: Reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system Biochemistry. 23: 4519-4525. PMID 6149763 DOI: 10.1021/Bi00315A003 |
0.745 |
|
1984 |
Lefkowitz RJ, Caron MG, Stiles GL. Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors. The New England Journal of Medicine. 310: 1570-9. PMID 6145093 DOI: 10.1056/Nejm198406143102406 |
0.731 |
|
1984 |
Stiles GL, Caron MG, Lefkowitz RJ. Beta-adrenergic receptors: biochemical mechanisms of physiological regulation. Physiological Reviews. 64: 661-743. PMID 6143332 DOI: 10.1152/Physrev.1984.64.2.661 |
0.748 |
|
1984 |
Nambi P, Sibley DR, Caron MG, Lefkowitz RJ. Photoaffinity labeling of beta-adrenergic receptors in mammalian tissues. Biochemical Pharmacology. 33: 3813-22. PMID 6095862 DOI: 10.1016/0006-2952(84)90045-5 |
0.74 |
|
1984 |
Caron MG, Leeb-Lundberg LM, Strader CD, Dickinson KE, Pickel VM, Joh T, Lefkowitz RJ. Molecular biology of adrenergic receptors in the rat and frog central nervous system. Hypertension. 6: II22-7. PMID 6094345 DOI: 10.1161/01.Hyp.6.5_Pt_2.Ii22 |
0.766 |
|
1984 |
Benovic JL, Shorr RGL, Caron MG, Lefkowitz RJ. The mammalian β2-adrenergic receptor: Purification and characterization Biochemistry. 23: 4510-4518. PMID 6093858 DOI: 10.1021/Bi00315A002 |
0.647 |
|
1984 |
Strulovici B, Cerione RA, Kilpatrick BF, Caron MG, Lefkowitz RJ. Direct demonstration of impaired functionality of a purified desensitized beta-adrenergic receptor in a reconstituted system. Science (New York, N.Y.). 225: 837-40. PMID 6089331 DOI: 10.1126/Science.6089331 |
0.714 |
|
1984 |
DeMarinis R, Krog A, Shah D, Lafferty J, Holden K, Hieble J, Matthews W, Regan J, Lefkowitz R, Caron M. Additions and Corrections-Development of an Affinity Ligand for Purification of Adrenoceptors from Human Platelet Membranes Journal of Medicinal Chemistry. 27: 1753-1753. DOI: 10.1021/Jm00378A603 |
0.617 |
|
1984 |
Shorr RGL, Kempner ES, Strohsacker MW, Nambi P, Lefkowitz RJ, Caron MG. Determination of the molecular size of frog and turkey erythrocyte .beta.-adrenergic receptors by radiation inactivation Biochemistry. 23: 747-753. DOI: 10.1021/Bi00299A025 |
0.693 |
|
1984 |
DEMARINIS RM, KROG AJ, SHAH DH, LAFFERTY J, HOLDEN KG, HIEBLE JP, MATTHEWS WD, REGAN JW, LEFKOWITZ RJ, CARON MG. ChemInform Abstract: DEVELOPMENT OF AN AFFINITY LIGAND FOR PURIFICATION OF α2-ADRENOCEPTORS FROM HUMAN PLATELET MEMBRANES Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198448242 |
0.358 |
|
1984 |
HEALD SL, JEFFS PW, LAVIN TN, NAMBI P, LEFKOWITZ RJ, CARON MG. ChemInform Abstract: Synthesis of Iodine-125 Labeled (±)-15-(4-Azidobenzyl)carazolol: A Potent β-Adrenergic Photoaffinity Probe. Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198408322 |
0.574 |
|
1983 |
Caron MG, Kilpatrick BF, Sibley DR. Direct radioligand measurement of dopamine receptors in the anterior pituitary gland. Methods in Enzymology. 103: 557-90. PMID 6669043 DOI: 10.1016/S0076-6879(83)03041-4 |
0.595 |
|
1983 |
Cerione RA, Strulovici B, Benovic JL, Lefkowitz RJ, Caron MG. Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase Nature. 306: 562-566. PMID 6316161 DOI: 10.1038/306562A0 |
0.737 |
|
1983 |
Leeb-Lundberg LM, Dickinson KE, Heald SL, Wikberg JE, DeBernardis JF, Winn M, Arendsen DL, Lefkowitz RJ, Caron MG. Covalent labeling of the cerebral cortex alpha 1-adrenergic receptor with a new high affinity radioiodinated photoaffinity probe. Biochemical and Biophysical Research Communications. 115: 946-51. PMID 6313003 DOI: 10.1016/S0006-291X(83)80026-6 |
0.724 |
|
1983 |
Cerione RA, Strulovici B, Benovic JL, Strader CD, Caron MG, Lefkowitz RJ. Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system. Proceedings of the National Academy of Sciences of the United States of America. 80: 4899-903. PMID 6308659 DOI: 10.1073/Pnas.80.16.4899 |
0.778 |
|
1983 |
Stadel JM, Nambi P, Shorr RG, Sawyer DF, Caron MG, Lefkowitz RJ. Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 80: 3173-7. PMID 6304694 DOI: 10.1073/Pnas.80.11.3173 |
0.75 |
|
1983 |
Heald SL, Jeffs PW, Lavin TN, Nambi P, Lefkowitz RJ, Caron MG. Synthesis of iodine-125 labeled (+/-)-15-(4-azidobenzyl)carazolol: a potent beta-adrenergic photoaffinity probe. Journal of Medicinal Chemistry. 26: 832-8. PMID 6304313 DOI: 10.1021/Jm00360A009 |
0.692 |
|
1983 |
Benovic JL, Stiles GL, Lefkowitz RJ, Caron MG. Photoaffinity labelling of mammalian beta-adrenergic receptors: Metal-dependent proteolysis explains apparent heterogeneity Biochemical and Biophysical Research Communications. 110: 504-511. PMID 6301455 DOI: 10.1016/0006-291X(83)91178-6 |
0.741 |
|
1983 |
Strader CD, Pickel VM, Joh TH, Strohsacker MW, Shorr RG, Lefkowitz RJ, Caron MG. Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain. Proceedings of the National Academy of Sciences of the United States of America. 80: 1840-4. PMID 6300875 DOI: 10.1073/Pnas.80.7.1840 |
0.559 |
|
1983 |
Stiles GL, Hoffman BB, Hubbard M, Caron MG, Lefkowitz RJ. Guanine nucleotides and alpha 1 adrenergic receptors in the heart. Biochemical Pharmacology. 32: 69-71. PMID 6299299 DOI: 10.1016/0006-2952(83)90654-8 |
0.723 |
|
1983 |
Wikberg JE, Lefkowitz RJ, Caron MG. Solubilization of rat liver alpha 1-adrenergic receptors. Agonist specific alteration in receptor binding affinity. Biochemical Pharmacology. 32: 3171-8. PMID 6139112 DOI: 10.1016/0006-2952(83)90200-9 |
0.541 |
|
1983 |
Wikberg JE, Akers M, Caron MG, Hagen PO. Norepinephrine-induced down regulation of alpha 1 adrenergic receptors in cultured rabbit aorta smooth muscle cells. Life Sciences. 33: 1409-17. PMID 6137750 DOI: 10.1016/0024-3205(83)90824-X |
0.314 |
|
1983 |
Lefkowitz RJ, Stadel JM, Caron MG. Adenylate cyclase-coupled beta-adrenergic receptors: structure and mechanisms of activation and desensitization. Annual Review of Biochemistry. 52: 159-86. PMID 6137187 DOI: 10.1146/ANNUREV.BI.52.070183.001111 |
0.554 |
|
1982 |
De Lean A, Kilpatrick BF, Caron MG. Guanine nucleotides regulate both dopaminergic agonist and antagonist binding in porcine anterior pituitary. Endocrinology. 110: 1064-6. PMID 7056223 DOI: 10.1210/ENDO-110-3-1064 |
0.378 |
|
1982 |
Shorr RG, Heald SL, Jeffs PW, Lavin TN, Strohsacker MW, Lefkowitz RJ, Caron MG. The beta-adrenergic receptor: rapid purification and covalent labeling by photoaffinity crosslinking. Proceedings of the National Academy of Sciences of the United States of America. 79: 2778-82. PMID 6283543 DOI: 10.1073/Pnas.79.9.2778 |
0.578 |
|
1982 |
Caron MG, Shorr RG, Lavin TN, Lefkowitz RJ. Molecular characterization of the beta-adrenergic receptor of frog erythrocytes. Metabolism: Clinical and Experimental. 31: 658-63. PMID 6283304 DOI: 10.1016/0026-0495(82)90195-0 |
0.564 |
|
1982 |
Regan JW, Barden N, Lefkowitz RJ, Caron MG, DeMarinis RM, Krog AJ, Holden KG, Matthews WD, Hieble JP. Affinity chromatography of human platelet α 2-adrenergic receptors Proceedings of the National Academy of Sciences of the United States of America. 79: 7223-7227. PMID 6130523 DOI: 10.1073/Pnas.79.23.7223 |
0.66 |
|
1981 |
Michel T, Hoffman BB, Lefkowitz RJ, Caron MG. Different sedimentation properties of agonist- and antagonist-labelled platelet alpha 2 adrenergic receptors. Biochemical and Biophysical Research Communications. 100: 1131-6. PMID 6268079 DOI: 10.1016/0006-291X(81)91941-0 |
0.682 |
|
1981 |
Pitha J, Zjawiony J, Lefkowitz RJ, Caron MG. Die Makromolekulare Chemie. 182: 1945-1950. DOI: 10.1002/MACP.1981.021820707 |
0.431 |
|
1980 |
Pitha J, Zjawiony J, Lefkowitz RJ, Caron MG. Macromolecular β-adrenergic antagonists discriminating between receptor and antibody Proceedings of the National Academy of Sciences of the United States of America. 77: 2219-2223. PMID 6154947 DOI: 10.1073/PNAS.77.4.2219 |
0.459 |
|
1980 |
Pitha J, Zjawiony J, Nasrin N, Lefkowitz RJ, Caron MG. Potent beta-adrenergic antagonist possessing chemically reactive group Life Sciences. 27: 1791-1798. PMID 6110155 DOI: 10.1016/0024-3205(80)90447-6 |
0.578 |
|
1980 |
Schocken DD, Caron MG, Lefkowitz RJ. The human placenta--a rich source of beta-adrenergic receptors: characterization of the receptors in particulate and solubilized preparations. The Journal of Clinical Endocrinology and Metabolism. 50: 1082-8. PMID 6103009 DOI: 10.1210/JCEM-50-6-1082 |
0.577 |
|
1979 |
Caron MG, Limbird LE, Lefkowitz RJ. Biochemical characterization of the beta-adrenergic receptor of the frog erythrocyte. Molecular and Cellular Biochemistry. 28: 45-66. PMID 231201 DOI: 10.1007/BF00223359 |
0.737 |
|
1979 |
Wood CL, Caron MG, Lefkowitz RJ. Separation of solubilized alpha and beta adrenergic receptors by affinity chromatography. Biochemical and Biophysical Research Communications. 88: 1-8. PMID 222278 DOI: 10.1016/0006-291X(79)91688-7 |
0.559 |
|
1979 |
Caron MG, Srinivasan Y, Snyderman R, Lefkowitz RJ. Antibodies raised against purified beta-adrenergic receptors specifically bind beta-adrenergic ligands. Proceedings of the National Academy of Sciences of the United States of America. 76: 2263-7. PMID 36615 DOI: 10.1073/PNAS.76.5.2263 |
0.542 |
|
1978 |
Bukowiecki LJ, Caron MG, Vallieres J, LeBlanc J. beta-adrenergic receptors in brown adipose tissue: identification by (-)[3H]dihydroalprenolol binding. Experientia. Supplementum. 32: 55-9. PMID 206459 DOI: 10.1007/978-3-0348-5559-4_5 |
0.307 |
|
1977 |
Caron MG, Gagne B, De Lean A. Identification of beta adrenergic receptors in rat hypothalamus. Canadian Journal of Biochemistry. 55: 693-9. PMID 19139 DOI: 10.1139/o77-100 |
0.321 |
|
1976 |
Caron MG, Lefkowitz RJ. Beta-Adrenergic receptors: solubilization of (-)(3H)alprenolol binding sites from frog erythrocyte membranes. Biochemical and Biophysical Research Communications. 68: 315-22. PMID 1082747 DOI: 10.1016/0006-291X(76)91145-1 |
0.496 |
|
1976 |
Mukherjee C, Caron MG, Lefkowitz RJ. Regulation of adenylate cyclase coupled beta-adrenergic receptors by beta-adrenergic catecholamines. Endocrinology. 99: 347-57. PMID 954636 DOI: 10.1210/endo-99-2-347 |
0.594 |
|
1976 |
Lefkowitz RJ, Limbird LE, Mukherjee C, Caron MG. The beta-adrenergic receptor and adenylate cyclase. Biochimica Et Biophysica Acta. 457: 1-39. PMID 769837 DOI: 10.1016/0304-4157(76)90012-5 |
0.724 |
|
1976 |
Caron MG, Lefkowitz RJ. Biological activity of agarose-immobilized catecholamines. Biochimica Et Biophysica Acta. 444: 472-86. PMID 9146 DOI: 10.1016/0304-4165(76)90391-3 |
0.486 |
|
1975 |
Mukherjee C, Caron MG, Lefkowitz RJ. Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of beta-adrenergic receptor binding sites. Proceedings of the National Academy of Sciences of the United States of America. 72: 1945-9. PMID 1057183 DOI: 10.1073/pnas.72.5.1945 |
0.525 |
|
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