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Marc Caron - Publications

Affiliations: 
Cell Biology Duke University, Durham, NC 
Website:
http://www.cellbio.duke.edu/faculty/research/caron.html

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Jacobsen JPR, Oh A, Bangle R, Roberts W, Royer EL, Modesto N, Windermere S, Yi Z, Vernon R, Cajina M, Urs NM, Snyder JC, Nicholls P, Sachs BD, Caron MG. Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31035282 DOI: 10.1038/s41386-019-0400-1  0.76
2019 Caron MG, Barak LS. A Brief History of the β-Arrestins. Methods in Molecular Biology (Clifton, N.J.). 1957: 3-8. PMID 30919344 DOI: 10.1007/978-1-4939-9158-7_1  0.88
2019 Martini ML, Liu J, Ray C, Yu X, Huang XP, Urs A, Urs NM, McCorvy J, Caron MG, Roth BL, Jin J. Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists. Journal of Medicinal Chemistry. PMID 30875219 DOI: 10.1021/acs.jmedchem.9b00351  0.76
2018 Hultman R, Ulrich K, Sachs BD, Blount C, Carlson DE, Ndubuizu N, Bagot RC, Parise EM, Vu MT, Gallagher NM, Wang J, Silva AJ, Deisseroth K, Mague SD, Caron MG, et al. Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability. Cell. PMID 29502969 DOI: 10.1016/j.cell.2018.02.012  0.56
2018 Pack TF, Orlen MI, Ray C, Peterson SM, Caron MG. The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation. The Journal of Biological Chemistry. PMID 29487132 DOI: 10.1074/jbc.RA117.001300  0.64
2018 Sachs BD, Tran HL, Folse E, Caron MG. Title: Brain-region-specific molecular responses to maternal separation and social defeat stress in mice. Neuroscience. PMID 29341883 DOI: 10.1016/j.neuroscience.2018.01.018  0.56
2017 Rose SJ, Pack TF, Peterson SM, Payne K, Borrelli E, Caron MG. Engineered D2R Variants Reveal the Balanced and Biased Contributions of G-Protein and β-Arrestin to Dopamine-Dependent Functions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29068002 DOI: 10.1038/npp.2017.254  0.64
2017 Toth K, Slosky LM, Pack TF, Urs NM, Boone P, Mao L, Abraham D, Caron MG, Barak LS. Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2. Synapse (New York, N.Y.). PMID 28941296 DOI: 10.1002/syn.22012  0.88
2017 Fakhouri L, Cook CD, Al-Huniti MH, Console-Bram LM, Hurst DP, Spano MBS, Nasrallah DJ, Caron MG, Barak LS, Reggio PH, Abood ME, Croatt MP. Design, synthesis and biological evaluation of GPR55 agonists. Bioorganic & Medicinal Chemistry. PMID 28673732 DOI: 10.1016/j.bmc.2017.06.016  0.88
2017 Zhu L, Rossi M, Cui Y, Lee RJ, Sakamoto W, Perry NA, Urs NM, Caron MG, Gurevich VV, Godlewski G, Kunos G, Chen M, Chen W, Wess J. Hepatic β-arrestin 2 is essential for maintaining euglycemia. The Journal of Clinical Investigation. PMID 28650340 DOI: 10.1172/JCI92913  0.76
2017 Snyder JC, Rochelle LK, Ray C, Pack TF, Bock CB, Lubkov V, Lyerly HK, Waggoner AS, Barak LS, Caron MG. Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled Receptor-5 diminishes cell fitness. The Journal of Biological Chemistry. PMID 28275053 DOI: 10.1074/jbc.M116.756635  0.88
2017 Le Gonidec S, Chaves-Almagro C, Bai Y, Kang HJ, Smith A, Wanecq E, Huang XP, Prats H, Knibiehler B, Roth BL, Barak LS, Caron MG, Valet P, Audigier Y, Masri B. Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28242772 DOI: 10.1096/fj.201601074R  0.88
2017 Zhu L, Almaça J, Dadi PK, Hong H, Sakamoto W, Rossi M, Lee RJ, Vierra NC, Lu H, Cui Y, McMillin SM, Perry NA, Gurevich VV, Lee A, Kuo B, ... ... Caron MG, et al. β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions. Nature Communications. 8: 14295. PMID 28145434 DOI: 10.1038/ncomms14295  0.76
2017 Ray C, Soderblom EJ, Bai Y, Carroll FI, Caron MG, Barak LS. Probing the Allosteric Role of the α5 Subunit of α3β4α5 Nicotinic Acetylcholine Receptors by Functionally Selective Modulators and Ligands. Acs Chemical Biology. PMID 28045487 DOI: 10.1021/acschembio.6b01117  0.88
2016 Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG. Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911814 DOI: 10.1073/pnas.1614347113  0.96
2016 Urs NM, Peterson SM, Caron MG. New Concepts in Dopamine D2 Receptor Biased Signaling and Implications for Schizophrenia Therapy. Biological Psychiatry. PMID 27832841 DOI: 10.1016/j.biopsych.2016.10.011  0.76
2016 Barak LS, Bai Y, Peterson S, Evron T, Urs N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Chung TD, Rodriguiz RM, Wetsel WC, Thomas JB, Hanson GR, Pinkerton AB, ... Caron MG, et al. ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse. Acs Chemical Biology. PMID 27119457 DOI: 10.1021/acschembio.6b00291  1
2016 Jacobsen JP, Rudder ML, Roberts W, Royer EL, Robinson TJ, Oh A, Spasojevic I, Sachs BD, Caron MG. SSRI Augmentation by 5-Hydroxytryptophan Slow-Release: Mouse Pharmacodynamic Proof-of-Concept. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26932820 DOI: 10.1038/npp.2016.35  0.56
2016 Meza-Aviña ME, Lingerfelt MA, Console-Bram LM, Gamage TF, Sharir H, Gettys KE, Hurst DP, Kotsikorou E, Shore DM, Caron MG, Rao N, Barak LS, Abood ME, Reggio PH, Croatt MP. Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones. Bioorganic & Medicinal Chemistry Letters. PMID 26916440 DOI: 10.1016/j.bmcl.2016.02.030  0.88
2015 Snyder JC, Pack TF, Rochelle LK, Chakraborty SK, Zhang M, Eaton AW, Bai Y, Ernst LA, Barak LS, Waggoner AS, Caron MG. A rapid and affordable screening platform for membrane protein trafficking. Bmc Biology. 13: 107. PMID 26678094 DOI: 10.1186/s12915-015-0216-3  1
2015 Peterson SM, Pack TF, Caron MG. Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity. Plos One. 10: e0141637. PMID 26516769 DOI: 10.1371/journal.pone.0141637  1
2015 Park SM, Chen M, Schmerberg CM, Dulman RS, Rodriguiz RM, Caron MG, Jin J, Wetsel WC. Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-like Behavior in Hypoglutamatergic Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26129680 DOI: 10.1038/npp.2015.196  1
2015 Peterson SM, Pack TF, Wilkins AD, Urs NM, Urban DJ, Bass CE, Lichtarge O, Caron MG. Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor. Proceedings of the National Academy of Sciences of the United States of America. 112: 7097-102. PMID 25964346 DOI: 10.1073/pnas.1502742112  1
2015 Urs NM, Bido S, Peterson SM, Daigle TL, Bass CE, Gainetdinov RR, Bezard E, Caron MG. Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 112: E2517-26. PMID 25918399 DOI: 10.1073/pnas.1502740112  1
2015 Gao Y, Peterson S, Masri B, Hougland MT, Adham N, Gyertyán I, Kiss B, Caron MG, El-Mallakh RS. Cariprazine exerts antimanic properties and interferes with dopamine D2 receptor β-arrestin interactions. Pharmacology Research & Perspectives. 3: e00073. PMID 25692006 DOI: 10.1002/prp2.73  0.68
2015 Sachs BD, Ni JR, Caron MG. Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress. Proceedings of the National Academy of Sciences of the United States of America. 112: 2557-62. PMID 25675490 DOI: 10.1073/pnas.1416866112  1
2015 Snyder JC, Rochelle LK, Marion S, Lyerly HK, Barak LS, Caron MG. Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions. Journal of Cell Science. 128: 1230-40. PMID 25653388 DOI: 10.1242/jcs.166322  1
2015 Sachs BD, Rodriguiz RM, Tran HL, Iyer A, Wetsel WC, Caron MG. Serotonin deficiency alters susceptibility to the long-term consequences of adverse early life experience. Psychoneuroendocrinology. 53: 69-81. PMID 25602134 DOI: 10.1016/j.psyneuen.2014.12.019  1
2015 Sachs BD, Caron MG. Chronic fluoxetine increases extra-hippocampal neurogenesis in adult mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25583694 DOI: 10.1093/ijnp/pyu029  1
2015 Burczyk M, Burkhalter MD, Blätte T, Matysik S, Caron MG, Barak LS, Philipp M. Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2. Biochemistry. 54: 765-75. PMID 25555130 DOI: 10.1021/bi501061h  1
2014 Evron T, Peterson SM, Urs NM, Bai Y, Rochelle LK, Caron MG, Barak LS. G Protein and β-arrestin signaling bias at the ghrelin receptor. The Journal of Biological Chemistry. 289: 33442-55. PMID 25261469 DOI: 10.1074/jbc.M114.581397  1
2014 Philipp M, Berger IM, Just S, Caron MG. Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development. The Journal of Biological Chemistry. 289: 26119-30. PMID 25104355 DOI: 10.1074/jbc.M114.551952  1
2014 Wang C, Wu H, Evron T, Vardy E, Han GW, Huang XP, Hufeisen SJ, Mangano TJ, Urban DJ, Katritch V, Cherezov V, Caron MG, Roth BL, Stevens RC. Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nature Communications. 5: 4355. PMID 25008467 DOI: 10.1038/ncomms5355  1
2014 Jacobsen JP, Plenge P, Sachs BD, Pehrson AL, Cajina M, Du Y, Roberts W, Rudder ML, Dalvi P, Robinson TJ, O'Neill SP, Khoo KS, Morillo CS, Zhang X, Caron MG. The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse. Psychopharmacology. 231: 4527-40. PMID 24810106 DOI: 10.1007/s00213-014-3595-1  1
2014 Daigle TL, Ferris MJ, Gainetdinov RR, Sotnikova TD, Urs NM, Jones SR, Caron MG. Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2450-62. PMID 24776686 DOI: 10.1038/npp.2014.97  1
2014 Urs NM, Nicholls PJ, Caron MG. Integrated approaches to understanding antipsychotic drug action at GPCRs. Current Opinion in Cell Biology. 27: 56-62. PMID 24680431 DOI: 10.1016/j.ceb.2013.11.002  1
2014 Marion S, Urs NM, Peterson SM, Sotnikova TD, Beaulieu JM, Gainetdinov RR, Caron MG. Dopamine D2 receptor relies upon PPM/PP2C protein phosphatases to dephosphorylate huntingtin protein. The Journal of Biological Chemistry. 289: 11715-24. PMID 24619418 DOI: 10.1074/jbc.M113.544312  1
2014 Sachs BD, Ni JR, Caron MG. Sex differences in response to chronic mild stress and congenital serotonin deficiency. Psychoneuroendocrinology. 40: 123-9. PMID 24485484 DOI: 10.1016/j.psyneuen.2013.11.008  1
2014 Hershberger PM, Hedrick MP, Peddibhotla S, Mangravita-Novo A, Gosalia P, Li Y, Gray W, Vicchiarelli M, Smith LH, Chung TD, Thomas JB, Caron MG, Pinkerton AB, Barak LS, Roth GP. Imidazole-derived agonists for the neurotensin 1 receptor. Bioorganic & Medicinal Chemistry Letters. 24: 262-7. PMID 24332089 DOI: 10.1016/j.bmcl.2013.11.026  1
2014 Sachs BD, Salahi AA, Caron MG. Congenital brain serotonin deficiency leads to reduced ethanol sensitivity and increased ethanol consumption in mice. Neuropharmacology. 77: 177-84. PMID 24067926 DOI: 10.1016/j.neuropharm.2013.09.010  1
2013 Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, ... ... Caron MG, et al. Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor. Acs Medicinal Chemistry Letters. 4: 846-851. PMID 24611085 DOI: 10.1021/ml400176n  1
2013 Snyder JC, Rochelle LK, Barak LS, Caron MG. The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment. Plos One. 8: e84476. PMID 24386388 DOI: 10.1371/journal.pone.0084476  1
2013 Kotsikorou E, Sharir H, Shore DM, Hurst DP, Lynch DL, Madrigal KE, Heynen-Genel S, Milan LB, Chung TD, Seltzman HH, Bai Y, Caron MG, Barak LS, Croatt MP, Abood ME, et al. Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry. 52: 9456-69. PMID 24274581 DOI: 10.1021/bi4008885  1
2013 Calipari ES, Ferris MJ, Salahpour A, Caron MG, Jones SR. Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression. Nature Communications. 4: 2720. PMID 24193139 DOI: 10.1038/ncomms3720  1
2013 Jørgensen CV, Jacobsen JP, Caron MG, Klein AB, Knudsen GM, Mikkelsen JD. Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice. Neuroscience Letters. 555: 118-22. PMID 24055299 DOI: 10.1016/j.neulet.2013.08.073  1
2013 Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M. Grk5l controls heart development by limiting mTOR signaling during symmetry breaking. Cell Reports. 4: 625-32. PMID 23972986 DOI: 10.1016/j.celrep.2013.07.036  1
2013 Barak LS, Bai Y, Snyder JC, Wang J, Chen W, Caron MG. Triphenylmethane dye activation of beta-arrestin. Biochemistry. 52: 5403-14. PMID 23865508 DOI: 10.1021/bi400217r  1
2013 Philipp M, Evron T, Caron MG. The role of arrestins in development. Progress in Molecular Biology and Translational Science. 118: 225-42. PMID 23764056 DOI: 10.1016/B978-0-12-394440-5.00009-7  1
2013 Sachs BD, Rodriguiz RM, Siesser WB, Kenan A, Royer EL, Jacobsen JP, Wetsel WC, Caron MG. The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2081-94. PMID 23672796 DOI: 10.1017/S1461145713000321  1
2013 Thakur GA, Bajaj S, Paronis C, Peng Y, Bowman AL, Barak LS, Caron MG, Parrish D, Deschamps JR, Makriyannis A. Novel adamantyl cannabinoids as CB1 receptor probes. Journal of Medicinal Chemistry. 56: 3904-21. PMID 23621789 DOI: 10.1021/jm4000775  1
2013 Dzirasa K, Kumar S, Sachs BD, Caron MG, Nicolelis MA. Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4505-13. PMID 23467366 DOI: 10.1523/JNEUROSCI.4891-12.2013  1
2013 Snyder JC, Rochelle LK, Lyerly HK, Caron MG, Barak LS. Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network. The Journal of Biological Chemistry. 288: 10286-97. PMID 23439653 DOI: 10.1074/jbc.M112.447540  1
2013 Siesser WB, Sachs BD, Ramsey AJ, Sotnikova TD, Beaulieu JM, Zhang X, Caron MG, Gainetdinov RR. Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice. Acs Chemical Neuroscience. 4: 84-8. PMID 23336047 DOI: 10.1021/cn300127h  1
2013 Farrell MS, Pei Y, Wan Y, Yadav PN, Daigle TL, Urban DJ, Lee HM, Sciaky N, Simmons A, Nonneman RJ, Huang XP, Hufeisen SJ, Guettier JM, Moy SS, Wess J, ... Caron MG, et al. A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 854-62. PMID 23303063 DOI: 10.1038/npp.2012.251  1
2013 Hara MR, Sachs BD, Caron MG, Lefkowitz RJ. Pharmacological blockade of a β(2)AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model. Cell Cycle (Georgetown, Tex.). 12: 219-24. PMID 23287463 DOI: 10.4161/cc.23368  1
2012 Wong P, Chang CC, Marx CE, Caron MG, Wetsel WC, Zhang X. Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice. Plos One. 7: e51455. PMID 23240026 DOI: 10.1371/journal.pone.0051455  1
2012 Urs NM, Snyder JC, Jacobsen JP, Peterson SM, Caron MG. Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action. Proceedings of the National Academy of Sciences of the United States of America. 109: 20732-7. PMID 23188793 DOI: 10.1073/pnas.1215489109  1
2012 Daigle TL, Caron MG. Elimination of GRK2 from cholinergic neurons reduces behavioral sensitivity to muscarinic receptor activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11461-6. PMID 22895728 DOI: 10.1523/JNEUROSCI.2234-12.2012  1
2012 Jacobsen JP, Medvedev IO, Caron MG. The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2444-59. PMID 22826344 DOI: 10.1098/rstb.2012.0109  1
2012 Anzalone A, Lizardi-Ortiz JE, Ramos M, De Mei C, Hopf FW, Iaccarino C, Halbout B, Jacobsen J, Kinoshita C, Welter M, Caron MG, Bonci A, Sulzer D, Borrelli E. Dual control of dopamine synthesis and release by presynaptic and postsynaptic dopamine D2 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9023-34. PMID 22745501 DOI: 10.1523/JNEUROSCI.0918-12.2012  1
2012 Frankowski KJ, Hedrick MP, Gosalia P, Li K, Shi S, Whipple D, Ghosh P, Prisinzano TE, Schoenen FJ, Su Y, Vasile S, Sergienko E, Gray W, Hariharan S, Milan L, ... ... Caron MG, et al. Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. Acs Chemical Neuroscience. 3: 221-236. PMID 22737280 DOI: 10.1021/cn200128x  1
2012 Kile BM, Walsh PL, McElligott ZA, Bucher ES, Guillot TS, Salahpour A, Caron MG, Wightman RM. Optimizing the Temporal Resolution of Fast-Scan Cyclic Voltammetry. Acs Chemical Neuroscience. 3: 285-292. PMID 22708011 DOI: 10.1021/cn200119u  1
2012 Revel FG, Moreau JL, Gainetdinov RR, Ferragud A, Velázquez-Sánchez C, Sotnikova TD, Morairty SR, Harmeier A, Groebke Zbinden K, Norcross RD, Bradaia A, Kilduff TS, Biemans B, Pouzet B, Caron MG, et al. Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics. Biological Psychiatry. 72: 934-42. PMID 22705041 DOI: 10.1016/j.biopsych.2012.05.014  1
2012 Managò F, Espinoza S, Salahpour A, Sotnikova TD, Caron MG, Premont RT, Gainetdinov RR. The role of GRK6 in animal models of Parkinson's disease and L-DOPA treatment. Scientific Reports. 2: 301. PMID 22393477 DOI: 10.1038/srep00301  1
2012 Salahpour A, Caron MG. Food for thought: the physiological relevance of ghrelin and dopamine D2 receptor heterodimerization in the regulation of appetite. Neuron. 73: 210-1. PMID 22284175 DOI: 10.1016/j.neuron.2012.01.004  1
2012 Evron T, Daigle TL, Caron MG. GRK2: multiple roles beyond G protein-coupled receptor desensitization. Trends in Pharmacological Sciences. 33: 154-64. PMID 22277298 DOI: 10.1016/j.tips.2011.12.003  1
2012 Zhong H, Sánchez C, Caron MG. Consideration of allosterism and interacting proteins in the physiological functions of the serotonin transporter. Biochemical Pharmacology. 83: 435-42. PMID 21983034 DOI: 10.1016/j.bcp.2011.09.020  1
2012 Meck WH, Cheng RK, MacDonald CJ, Gainetdinov RR, Caron MG, Cevik MÖ. Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice. Neuropharmacology. 62: 1221-9. PMID 21296093 DOI: 10.1016/j.neuropharm.2011.01.042  1
2011 Guzman MS, De Jaeger X, Raulic S, Souza IA, Li AX, Schmid S, Menon RS, Gainetdinov RR, Caron MG, Bartha R, Prado VF, Prado MA. Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission. Plos Biology. 9: e1001194. PMID 22087075 DOI: 10.1371/journal.pbio.1001194  1
2011 Daigle TL, Wetsel WC, Caron MG. Opposite function of dopamine D1 and N-methyl-D-aspartate receptors in striatal cannabinoid-mediated signaling. The European Journal of Neuroscience. 34: 1378-89. PMID 22034973 DOI: 10.1111/j.1460-9568.2011.07874.x  1
2011 Marder SR, Roth B, Sullivan PF, Scolnick EM, Nestler EJ, Geyer MA, Welnberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, ... ... Caron MG, et al. Advancing drug discovery for schizophrenia. Annals of the New York Academy of Sciences. 1236: 30-43. PMID 22032400 DOI: 10.1111/j.1749-6632.2011.06216.x  1
2011 Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, ... Caron MG, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/pnas.1104807108  1
2011 Herrmann R, Heflin SJ, Hammond T, Lee B, Wang J, Gainetdinov RR, Caron MG, Eggers ED, Frishman LJ, McCall MA, Arshavsky VY. Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA. Neuron. 72: 101-10. PMID 21982372 DOI: 10.1016/j.neuron.2011.07.030  1
2011 Espinoza S, Salahpour A, Masri B, Sotnikova TD, Messa M, Barak LS, Caron MG, Gainetdinov RR. Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor. Molecular Pharmacology. 80: 416-25. PMID 21670104 DOI: 10.1124/mol.111.073304  1
2011 Evron T, Philipp M, Lu J, Meloni AR, Burkhalter M, Chen W, Caron MG. Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling. The Journal of Biological Chemistry. 286: 27676-86. PMID 21659505 DOI: 10.1074/jbc.M111.234666  1
2011 Jocoy EL, André VM, Cummings DM, Rao SP, Wu N, Ramsey AJ, Caron MG, Cepeda C, Levine MS. Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum. Frontiers in Systems Neuroscience. 5: 28. PMID 21617735 DOI: 10.3389/fnsys.2011.00028  1
2011 Kotsikorou E, Madrigal KE, Hurst DP, Sharir H, Lynch DL, Heynen-Genel S, Milan LB, Chung TD, Seltzman HH, Bai Y, Caron MG, Barak L, Abood ME, Reggio PH. Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry. 50: 5633-47. PMID 21534610 DOI: 10.1021/bi200010k  1
2011 Revel FG, Moreau JL, Gainetdinov RR, Bradaia A, Sotnikova TD, Mory R, Durkin S, Zbinden KG, Norcross R, Meyer CA, Metzler V, Chaboz S, Ozmen L, Trube G, Pouzet B, ... ... Caron MG, et al. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8485-90. PMID 21525407 DOI: 10.1073/pnas.1103029108  1
2011 Soderblom EJ, Philipp M, Thompson JW, Caron MG, Moseley MA. Quantitative label-free phosphoproteomics strategy for multifaceted experimental designs. Analytical Chemistry. 83: 3758-64. PMID 21491946 DOI: 10.1021/ac200213b  1
2011 Ramsey AJ, Milenkovic M, Oliveira AF, Escobedo-Lozoya Y, Seshadri S, Salahpour A, Sawa A, Yasuda R, Caron MG. Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 5795-800. PMID 21436042 DOI: 10.1073/pnas.1012621108  1
2011 Martins-Silva C, De Jaeger X, Guzman MS, Lima RD, Santos MS, Kushmerick C, Gomez MV, Caron MG, Prado MA, Prado VF. Novel strains of mice deficient for the vesicular acetylcholine transporter: insights on transcriptional regulation and control of locomotor behavior. Plos One. 6: e17611. PMID 21423695 DOI: 10.1371/journal.pone.0017611  1
2011 Mathurin K, Gallant MA, Germain P, Allard-Chamard H, Brisson J, Iorio-Morin C, de Brum Fernandes A, Caron MG, Laporte SA, Parent JL. An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production. The Journal of Biological Chemistry. 286: 2696-706. PMID 21112970 DOI: 10.1074/jbc.M110.178277  1
2011 Omenetti A, Yang L, Gainetdinov RR, Guy CD, Choi SS, Chen W, Caron MG, Diehl AM. Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G303-15. PMID 21071507 DOI: 10.1152/ajpgi.00368.2010  1
2011 Urs NM, Daigle TL, Caron MG. A dopamine D1 receptor-dependent β-arrestin signaling complex potentially regulates morphine-induced psychomotor activation but not reward in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 551-8. PMID 20980993 DOI: 10.1038/npp.2010.186  1
2010 Li Z, Caron MG, Blakely RD, Margolis KG, Gershon MD. Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16730-40. PMID 21148012 DOI: 10.1523/JNEUROSCI.2276-10.2010  1
2010 Sotnikova TD, Beaulieu JM, Espinoza S, Masri B, Zhang X, Salahpour A, Barak LS, Caron MG, Gainetdinov RR. The dopamine metabolite 3-methoxytyramine is a neuromodulator. Plos One. 5: e13452. PMID 20976142 DOI: 10.1371/journal.pone.0013452  1
2010 Kenakin T, Agnati LF, Caron M, Fredholm B, Guidoli D, Kobilka B, Lefkowitz RW, Lohse M, Woods A, Fuxe K. International Workshop at the Nobel Forum, Karolinska Institutet on G protein-coupled receptors: finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached? Journal of Receptor and Signal Transduction Research. 30: 284-6. PMID 20858022 DOI: 10.3109/10799893.2010.512438  1
2010 Zhao P, Sharir H, Kapur A, Cowan A, Geller EB, Adler MW, Seltzman HH, Reggio PH, Heynen-Genel S, Sauer M, Chung TD, Bai Y, Chen W, Caron MG, Barak LS, et al. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Molecular Pharmacology. 78: 560-8. PMID 20826425 DOI: 10.1124/mol.110.066746  1
2010 Siesser WB, Zhang X, Jacobsen JP, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice. Neuroscience Letters. 481: 6-11. PMID 20600620 DOI: 10.1016/j.neulet.2010.06.035  1
2010 Dzirasa K, Phillips HW, Sotnikova TD, Salahpour A, Kumar S, Gainetdinov RR, Caron MG, Nicolelis MA. Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6387-97. PMID 20445065 DOI: 10.1523/JNEUROSCI.0764-10.2010  1
2010 Bowton E, Saunders C, Erreger K, Sakrikar D, Matthies HJ, Sen N, Jessen T, Colbran RJ, Caron MG, Javitch JA, Blakely RD, Galli A. Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6048-57. PMID 20427663 DOI: 10.1523/JNEUROSCI.5094-09.2010  1
2010 Lara A, Damasceno DD, Pires R, Gros R, Gomes ER, Gavioli M, Lima RF, Guimarães D, Lima P, Bueno CR, Vasconcelos A, Roman-Campos D, Menezes CA, Sirvente RA, Salemi VM, ... ... Caron MG, et al. Dysautonomia due to reduced cholinergic neurotransmission causes cardiac remodeling and heart failure. Molecular and Cellular Biology. 30: 1746-56. PMID 20123977 DOI: 10.1128/MCB.00996-09  1
2009 Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W. G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. The Journal of Biological Chemistry. 284: 35040-8. PMID 19801552 DOI: 10.1074/jbc.M109.047456  1
2009 Kapur A, Zhao P, Sharir H, Bai Y, Caron MG, Barak LS, Abood ME. Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands. The Journal of Biological Chemistry. 284: 29817-27. PMID 19723626 DOI: 10.1074/jbc.M109.050187  1
2009 Haenisch B, Bilkei-Gorzo A, Caron MG, Bönisch H. Knockout of the norepinephrine transporter and pharmacologically diverse antidepressants prevent behavioral and brain neurotrophin alterations in two chronic stress models of depression. Journal of Neurochemistry. 111: 403-16. PMID 19694905 DOI: 10.1111/j.1471-4159.2009.06345.x  1
2009 de Castro BM, De Jaeger X, Martins-Silva C, Lima RD, Amaral E, Menezes C, Lima P, Neves CM, Pires RG, Gould TW, Welch I, Kushmerick C, Guatimosim C, Izquierdo I, Cammarota M, ... ... Caron MG, et al. The vesicular acetylcholine transporter is required for neuromuscular development and function. Molecular and Cellular Biology. 29: 5238-50. PMID 19635813 DOI: 10.1128/MCB.00245-09  1
2009 Dzirasa K, Ramsey AJ, Takahashi DY, Stapleton J, Potes JM, Williams JK, Gainetdinov RR, Sameshima K, Caron MG, Nicolelis MA. Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8215-24. PMID 19553461 DOI: 10.1523/JNEUROSCI.1773-09.2009  1
2009 Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL. PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7124-36. PMID 19494135 DOI: 10.1523/JNEUROSCI.1090-09.2009  1
2009 Singer D, Camargo SM, Huggel K, Romeo E, Danilczyk U, Kuba K, Chesnov S, Caron MG, Penninger JM, Verrey F. Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3. The Journal of Biological Chemistry. 284: 19953-60. PMID 19478081 DOI: 10.1074/jbc.M109.011171  1
2009 Caron MG, Wightman RM. "To learn, you must pay attention." Molecular insights into teachers' wisdom. Proceedings of the National Academy of Sciences of the United States of America. 106: 7267-8. PMID 19416916 DOI: 10.1073/pnas.0903306106  1
2009 Sotnikova TD, Caron MG, Gainetdinov RR. Trace amine-associated receptors as emerging therapeutic targets. Molecular Pharmacology. 76: 229-35. PMID 19389919 DOI: 10.1124/mol.109.055970  1
2009 Dzirasa K, Santos LM, Ribeiro S, Stapleton J, Gainetdinov RR, Caron MG, Nicolelis MA. Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep. Plos One. 4: e5238. PMID 19381303 DOI: 10.1371/journal.pone.0005238  1
2009 Fuentes R, Petersson P, Siesser WB, Caron MG, Nicolelis MA. Spinal cord stimulation restores locomotion in animal models of Parkinson's disease. Science (New York, N.Y.). 323: 1578-82. PMID 19299613 DOI: 10.1126/science.1164901  1
2009 Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/nchembio0309-131  1
2009 Philipp M, Caron MG. Hedgehog signaling: is Smo a G protein-coupled receptor? Current Biology : Cb. 19: R125-7. PMID 19211052 DOI: 10.1016/j.cub.2008.12.010  0.56
2009 Kocerha J, Faghihi MA, Lopez-Toledano MA, Huang J, Ramsey AJ, Caron MG, Sales N, Willoughby D, Elmen J, Hansen HF, Orum H, Kauppinen S, Kenny PJ, Wahlestedt C. MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 106: 3507-12. PMID 19196972 DOI: 10.1073/pnas.0805854106  1
2009 Ghisi V, Ramsey AJ, Masri B, Gainetdinov RR, Caron MG, Salahpour A. Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter. Cellular Signalling. 21: 87-94. PMID 18929645 DOI: 10.1016/j.cellsig.2008.09.011  1
2009 Beaulieu JM, Gainetdinov RR, Caron MG. Akt/GSK3 signaling in the action of psychotropic drugs. Annual Review of Pharmacology and Toxicology. 49: 327-47. PMID 18928402 DOI: 10.1146/annurev.pharmtox.011008.145634  1
2008 Beaulieu JM, Caron MG. Looking at lithium: molecular moods and complex behaviour. Molecular Interventions. 8: 230-41. PMID 19015387 DOI: 10.1124/mi.8.5.8  1
2008 Tiruchinapalli DM, Caron MG, Keene JD. Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain. Journal of Neurochemistry. 107: 1529-43. PMID 19014379 DOI: 10.1111/j.1471-4159.2008.05718.x  1
2008 Philipp M, Fralish GB, Meloni AR, Chen W, MacInnes AW, Barak LS, Caron MG. Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase. Molecular Biology of the Cell. 19: 5478-89. PMID 18815277 DOI: 10.1091/mbc.E08-05-0448  1
2008 Masri B, Salahpour A, Didriksen M, Ghisi V, Beaulieu JM, Gainetdinov RR, Caron MG. Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics. Proceedings of the National Academy of Sciences of the United States of America. 105: 13656-61. PMID 18768802 DOI: 10.1073/pnas.0803522105  1
2008 Perona MT, Waters S, Hall FS, Sora I, Lesch KP, Murphy DL, Caron M, Uhl GR. Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions. Behavioural Pharmacology. 19: 566-74. PMID 18690111 DOI: 10.1097/FBP.0b013e32830cd80f  1
2008 Powell SB, Young JW, Ong JC, Caron MG, Geyer MA. Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behavioural Pharmacology. 19: 562-5. PMID 18690110 DOI: 10.1097/FBP.0b013e32830dc110  1
2008 Sotnikova TD, Zorina OI, Ghisi V, Caron MG, Gainetdinov RR. Trace amine associated receptor 1 and movement control. Parkinsonism & Related Disorders. 14: S99-102. PMID 18585080 DOI: 10.1016/j.parkreldis.2008.04.006  1
2008 Barak LS, Salahpour A, Zhang X, Masri B, Sotnikova TD, Ramsey AJ, Violin JD, Lefkowitz RJ, Caron MG, Gainetdinov RR. Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor. Molecular Pharmacology. 74: 585-94. PMID 18524885 DOI: 10.1124/mol.108.048884  1
2008 de Araujo IE, Oliveira-Maia AJ, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis MA, Simon SA. Food reward in the absence of taste receptor signaling. Neuron. 57: 930-41. PMID 18367093 DOI: 10.1016/j.neuron.2008.01.032  1
2008 Salahpour A, Ramsey AJ, Medvedev IO, Kile B, Sotnikova TD, Holmstrand E, Ghisi V, Nicholls PJ, Wong L, Murphy K, Sesack SR, Wightman RM, Gainetdinov RR, Caron MG. Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 105: 4405-10. PMID 18347339 DOI: 10.1073/pnas.0707646105  1
2008 Murphy KL, Zhang X, Gainetdinov RR, Beaulieu JM, Caron MG. A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression. The Journal of Biological Chemistry. 283: 13216-24. PMID 18339632 DOI: 10.1074/jbc.M706749200  1
2008 Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Cools MJ, Wetsel WC, Gainetdinov RR, Caron MG. Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. Proceedings of the National Academy of Sciences of the United States of America. 105: 1333-8. PMID 18212115 DOI: 10.1073/pnas.0711496105  1
2008 Beaulieu JM, Marion S, Rodriguiz RM, Medvedev IO, Sotnikova TD, Ghisi V, Wetsel WC, Lefkowitz RJ, Gainetdinov RR, Caron MG. A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell. 132: 125-36. PMID 18191226 DOI: 10.1016/j.cell.2007.11.041  1
2008 Ramsey AJ, Laakso A, Cyr M, Sotnikova TD, Salahpour A, Medvedev IO, Dykstra LA, Gainetdinov RR, Caron MG. Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2701-14. PMID 18185498 DOI: 10.1038/sj.npp.1301663  1
2008 Jensen NH, Rodriguiz RM, Caron MG, Wetsel WC, Rothman RB, Roth BL. N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2303-12. PMID 18059438 DOI: 10.1038/sj.npp.1301646  1
2008 Kim KM, Caron MG. Complementary roles of the DRY motif and C-terminus tail of GPCRS for G protein coupling and beta-arrestin interaction. Biochemical and Biophysical Research Communications. 366: 42-7. PMID 18036556 DOI: 10.1016/j.bbrc.2007.11.055  1
2007 Fukui M, Rodriguiz RM, Zhou J, Jiang SX, Phillips LE, Caron MG, Wetsel WC. Vmat2 heterozygous mutant mice display a depressive-like phenotype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10520-9. PMID 17898223 DOI: 10.1523/JNEUROSCI.4388-06.2007  1
2007 Marion S, Fralish GB, Laporte S, Caron MG, Barak LS. N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins. The Journal of Biological Chemistry. 282: 18937-44. PMID 17456469 DOI: 10.1074/jbc.M700090200  0.88
2007 Zhang J, Vinuela A, Neely MH, Hallett PJ, Grant SG, Miller GM, Isacson O, Caron MG, Yao WD. Inhibition of the dopamine D1 receptor signaling by PSD-95. The Journal of Biological Chemistry. 282: 15778-89. PMID 17369255 DOI: 10.1074/jbc.M611485200  1
2007 Beaulieu JM, Gainetdinov RR, Caron MG. The Akt-GSK-3 signaling cascade in the actions of dopamine. Trends in Pharmacological Sciences. 28: 166-72. PMID 17349698 DOI: 10.1016/j.tips.2007.02.006  1
2007 Vincent SG, Waddell AE, Caron MG, Walker JK, Fisher JT. A murine model of hyperdopaminergic state displays altered respiratory control. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1463-71. PMID 17255472 DOI: 10.1096/fj.06-7248com  1
2007 Beaulieu JM, Tirotta E, Sotnikova TD, Masri B, Salahpour A, Gainetdinov RR, Borrelli E, Caron MG. Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 881-5. PMID 17251429 DOI: 10.1523/JNEUROSCI.5074-06.2007  1
2007 Salahpour A, Medvedev IO, Beaulieu JM, Gainetdinov RR, Caron MG. Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals. Biological Psychiatry. 61: 65-9. PMID 16712807 DOI: 10.1016/j.biopsych.2006.03.020  1
2006 Caron MG, Gainetdinov RR. Dopamine: from pharmacology to molecular biology and back. Wiener Klinische Wochenschrift. 118: 565-8. PMID 17136328 DOI: 10.1007/s00508-006-0735-6  1
2006 Cyr M, Sotnikova TD, Gainetdinov RR, Caron MG. Dopamine enhances motor and neuropathological consequences of polyglutamine expanded huntingtin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2541-3. PMID 17065224 DOI: 10.1096/fj.06-6533fje  1
2006 Costa RM, Lin SC, Sotnikova TD, Cyr M, Gainetdinov RR, Caron MG, Nicolelis MA. Rapid alterations in corticostriatal ensemble coordination during acute dopamine-dependent motor dysfunction. Neuron. 52: 359-69. PMID 17046697 DOI: 10.1016/j.neuron.2006.07.030  1
2006 Dzirasa K, Ribeiro S, Costa R, Santos LM, Lin SC, Grosmark A, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis MA. Dopaminergic control of sleep-wake states. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10577-89. PMID 17035544 DOI: 10.1523/JNEUROSCI.1767-06.2006  1
2006 Sotnikova TD, Caron MG, Gainetdinov RR. DDD mice, a novel acute mouse model of Parkinson's disease. Neurology. 67: S12-7. PMID 17030735  1
2006 Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice. The Journal of Biological Chemistry. 281: 32072-80. PMID 16954211 DOI: 10.1074/jbc.M606062200  1
2006 Prado VF, Martins-Silva C, de Castro BM, Lima RF, Barros DM, Amaral E, Ramsey AJ, Sotnikova TD, Ramirez MR, Kim HG, Rossato JI, Koenen J, Quan H, Cota VR, Moraes MF, ... ... Caron MG, et al. Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. Neuron. 51: 601-12. PMID 16950158 DOI: 10.1016/j.neuron.2006.08.005  1
2006 Meloni AR, Fralish GB, Kelly P, Salahpour A, Chen JK, Wechsler-Reya RJ, Lefkowitz RJ, Caron MG. Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2. Molecular and Cellular Biology. 26: 7550-60. PMID 16908539 DOI: 10.1128/MCB.00546-06  1
2006 Sotnikova TD, Beaulieu JM, Gainetdinov RR, Caron MG. Molecular biology, pharmacology and functional role of the plasma membrane dopamine transporter. Cns & Neurological Disorders Drug Targets. 5: 45-56. PMID 16613553 DOI: 10.2174/187152706784111579  1
2006 Marion S, Oakley RH, Kim KM, Caron MG, Barak LS. A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors. The Journal of Biological Chemistry. 281: 2932-8. PMID 16319069 DOI: 10.1074/jbc.M508074200  0.88
2005 Beaulieu JM, Caron MG. Beta-arrestin goes nuclear. Cell. 123: 755-7. PMID 16325568 DOI: 10.1016/j.cell.2005.11.010  1
2005 Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell. 122: 261-73. PMID 16051150 DOI: 10.1016/j.cell.2005.05.012  1
2005 Sotnikova TD, Beaulieu JM, Barak LS, Wetsel WC, Caron MG, Gainetdinov RR. Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. Plos Biology. 3: e271. PMID 16050778 DOI: 10.1371/journal.pbio.0030271  1
2005 Cyr M, Caron MG, Johnson GA, Laakso A. Magnetic resonance imaging at microscopic resolution reveals subtle morphological changes in a mouse model of dopaminergic hyperfunction. Neuroimage. 26: 83-90. PMID 15862208 DOI: 10.1016/j.neuroimage.2005.01.039  0.68
2005 Pogorelov VM, Rodriguiz RM, Insco ML, Caron MG, Wetsel WC. Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1818-31. PMID 15856082 DOI: 10.1038/sj.npp.1300724  1
2005 Vroon A, Kavelaars A, Limmroth V, Lombardi MS, Goebel MU, Van Dam AM, Caron MG, Schedlowski M, Heijnen CJ. G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 174: 4400-6. PMID 15778405  1
2005 Medvedev IO, Gainetdinov RR, Sotnikova TD, Bohn LM, Caron MG, Dykstra LA. Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice. Psychopharmacology. 180: 408-13. PMID 15719221 DOI: 10.1007/s00213-005-2173-y  1
2005 Zhang X, Gainetdinov RR, Beaulieu JM, Sotnikova TD, Burch LH, Williams RB, Schwartz DA, Krishnan KR, Caron MG. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron. 45: 11-6. PMID 15629698 DOI: 10.1016/j.neuron.2004.12.014  1
2004 Wilbanks AM, Fralish GB, Kirby ML, Barak LS, Li YX, Caron MG. Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway. Science (New York, N.Y.). 306: 2264-7. PMID 15618520 DOI: 10.1126/science.1104193  1
2004 Torres GE, Sweeney AL, Beaulieu JM, Shashidharan P, Caron MG. Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant. Proceedings of the National Academy of Sciences of the United States of America. 101: 15650-5. PMID 15505207 DOI: 10.1073/pnas.0308088101  1
2004 Sotnikova TD, Budygin EA, Jones SR, Dykstra LA, Caron MG, Gainetdinov RR. Dopamine transporter-dependent and -independent actions of trace amine beta-phenylethylamine. Journal of Neurochemistry. 91: 362-73. PMID 15447669 DOI: 10.1111/j.1471-4159.2004.02721.x  1
2004 Zhang X, Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase-2 controls brain serotonin synthesis. Science (New York, N.Y.). 305: 217. PMID 15247473 DOI: 10.1126/science.1097540  1
2004 Gainetdinov RR, Premont RT, Bohn LM, Lefkowitz RJ, Caron MG. Desensitization of G protein-coupled receptors and neuronal functions. Annual Review of Neuroscience. 27: 107-44. PMID 15217328 DOI: 10.1146/annurev.neuro.27.070203.144206  1
2004 Xu M, Petraschka M, McLaughlin JP, Westenbroek RE, Caron MG, Lefkowitz RJ, Czyzyk TA, Pintar JE, Terman GW, Chavkin C. Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4576-84. PMID 15140929 DOI: 10.1523/JNEUROSCI.5552-03.2004  1
2004 Quan H, Athirakul K, Wetsel WC, Torres GE, Stevens R, Chen YT, Coffman TM, Caron MG. Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2. Molecular and Cellular Biology. 24: 4166-73. PMID 15121838 DOI: 10.1128/MCB.24.10.4166-4173.2004  1
2004 Beaulieu JM, Sotnikova TD, Yao WD, Kockeritz L, Woodgett JR, Gainetdinov RR, Caron MG. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. 101: 5099-104. PMID 15044694 DOI: 10.1073/pnas.0307921101  1
2004 Bohn LM, Gainetdinov RR, Caron MG. G protein-coupled receptor kinase/beta-arrestin systems and drugs of abuse: psychostimulant and opiate studies in knockout mice. Neuromolecular Medicine. 5: 41-50. PMID 15001811 DOI: 10.1385/NMM:5:1:041  1
2004 Yao WD, Gainetdinov RR, Arbuckle MI, Sotnikova TD, Cyr M, Beaulieu JM, Torres GE, Grant SG, Caron MG. Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron. 41: 625-38. PMID 14980210 DOI: 10.1016/S0896-6273(04)00048-0  1
2004 Terman GW, Jin W, Cheong YP, Lowe J, Caron MG, Lefkowitz RJ, Chavkin C. G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal. British Journal of Pharmacology. 141: 55-64. PMID 14662727 DOI: 10.1038/sj.bjp.0705595  1
2004 McLaughlin JP, Myers LC, Zarek PE, Caron MG, Lefkowitz RJ, Czyzyk TA, Pintar JE, Chavkin C. Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance. The Journal of Biological Chemistry. 279: 1810-8. PMID 14597630 DOI: 10.1074/jbc.M305796200  1
2004 Ferguson SS, Caron MG. Green fluorescent protein-tagged beta-arrestin translocation as a measure of G protein-coupled receptor activation. Methods in Molecular Biology (Clifton, N.J.). 237: 121-6. PMID 14501044  0.88
2003 Barak LS, Wilbanks AM, Caron MG. Constitutive desensitization: a new paradigm for g protein-coupled receptor regulation. Assay and Drug Development Technologies. 1: 339-46. PMID 15090199 DOI: 10.1089/15406580360545152  1
2003 Bohn LM, Gainetdinov RR, Sotnikova TD, Medvedev IO, Lefkowitz RJ, Dykstra LA, Caron MG. Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10265-73. PMID 14614085  1
2003 Johnson EC, Bohn LM, Barak LS, Birse RT, Nässel DR, Caron MG, Taghert PH. Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions. The Journal of Biological Chemistry. 278: 52172-8. PMID 14555656 DOI: 10.1074/jbc.M306756200  1
2003 Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science (New York, N.Y.). 301: 1391-4. PMID 12958364 DOI: 10.1126/science.1082808  1
2003 Cyr M, Beaulieu JM, Laakso A, Sotnikova TD, Yao WD, Bohn LM, Gainetdinov RR, Caron MG. Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 100: 11035-40. PMID 12958210 DOI: 10.1073/pnas.1831768100  1
2003 Gainetdinov RR, Bohn LM, Sotnikova TD, Cyr M, Laakso A, Macrae AD, Torres GE, Kim KM, Lefkowitz RJ, Caron MG, Premont RT. Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice. Neuron. 38: 291-303. PMID 12718862 DOI: 10.1016/S0896-6273(03)00192-2  1
2003 Tohgo A, Choy EW, Gesty-Palmer D, Pierce KL, Laporte S, Oakley RH, Caron MG, Lefkowitz RJ, Luttrell LM. The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. The Journal of Biological Chemistry. 278: 6258-67. PMID 12473660 DOI: 10.1074/jbc.M212231200  1
2002 Bohn LM, Lefkowitz RJ, Caron MG. Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10494-500. PMID 12451149  1
2002 Barbosa J, Ferreira LT, Martins-Silva C, Santos MS, Torres GE, Caron MG, Gomez MV, Ferguson SS, Prado MA, Prado VF. Trafficking of the vesicular acetylcholine transporter in SN56 cells: a dynamin-sensitive step and interaction with the AP-2 adaptor complex. Journal of Neurochemistry. 82: 1221-8. PMID 12358769 DOI: 10.1046/j.1471-4159.2002.01068.x  1
2002 Wilbanks AM, Laporte SA, Bohn LM, Barak LS, Caron MG. Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors. Biochemistry. 41: 11981-9. PMID 12356298 DOI: 10.1021/bi020275m  1
2002 Carneiro AM, Ingram SL, Beaulieu JM, Sweeney A, Amara SG, Thomas SM, Caron MG, Torres GE. The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7045-54. PMID 12177201  1
2002 Savelieva KV, Caudle WM, Findlay GS, Caron MG, Miller GW. Decreased ethanol preference and consumption in dopamine transporter female knock-out mice. Alcoholism, Clinical and Experimental Research. 26: 758-64. PMID 12068242 DOI: 10.1097/00000374-200206000-00003  1
2002 Claing A, Laporte SA, Caron MG, Lefkowitz RJ. Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins. Progress in Neurobiology. 66: 61-79. PMID 11900882 DOI: 10.1016/S0301-0082(01)00023-5  1
2002 Seachrist JL, Laporte SA, Dale LB, Babwah AV, Caron MG, Anborgh PH, Ferguson SS. Rab5 association with the angiotensin II type 1A receptor promotes Rab5 GTP binding and vesicular fusion. The Journal of Biological Chemistry. 277: 679-85. PMID 11682489 DOI: 10.1074/jbc.M109022200  1
1999 Walker JKL, Peppel K, Lefkowitz RJ, Caron MG, Fisher JT. Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 276: R1214-R1221. PMID 29592499 DOI: 10.1152/ajpregu.1999.276.4.R1214  0.96
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