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Marc Caron - Publications

Affiliations: 
Cell Biology Duke University, Durham, NC 
Website:
http://www.cellbio.duke.edu/faculty/research/caron.html

487 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Favier M, Janickova H, Justo D, Kljakic O, Runtz L, Natsheh JY, Pascoal TA, Germann J, Gallino D, Kang JI, Meng XQ, Antinora C, Raulic S, Jacobsen JP, Moquin L, ... ... Caron MG, et al. Cholinergic dysfunction in the dorsal striatum promotes habit formation and maladaptive eating. The Journal of Clinical Investigation. PMID 33164988 DOI: 10.1172/JCI138532  0.76
2020 Slosky LM, Bai Y, Toth K, Ray C, Rochelle LK, Badea A, Chandrasekhar R, Pogorelov VM, Abraham DM, Atluri N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney P, Yuan H, ... ... Caron MG, et al. β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors. Cell. PMID 32470395 DOI: 10.1016/j.cell.2020.04.053  0.8
2019 Toth K, Nagi K, Slosky LM, Rochelle L, Ray C, Kaur S, Shenoy SK, Caron MG, Barak LS. Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs. Acs Pharmacology & Translational Science. 2: 230-246. PMID 32259059 DOI: 10.1021/acsptsci.9b00018  0.8
2019 Li YC, Panikker P, Xing B, Yang SS, Alexandropoulos C, McEachern EP, Akumuo R, Zhao E, Gulchina Y, Pletnikov MV, Urs NM, Caron MG, Elefant F, Gao WJ. Deletion of Glycogen Synthase Kinase-3β in D Receptor-Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor-Dependent Synaptic Plasticity. Biological Psychiatry. PMID 31892408 DOI: 10.1016/j.biopsych.2019.10.025  0.76
2019 Boone PG, Rochelle LK, Ginzel JD, Lubkov V, Roberts WL, Nicholls PJ, Bock C, Flowers ML, von Furstenberg RJ, Stripp BR, Agarwal P, Borowsky AD, Cardiff RD, Barak LS, Caron MG, et al. A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion. Nature Communications. 10: 5490. PMID 31792216 DOI: 10.1038/s41467-019-13330-y  0.8
2019 Porter-Stransky KA, Petko AK, Karne SL, Liles LC, Urs NM, Caron MG, Paladini CA, Weinshenker D. Loss of β-arrestin2 in D2 cells alters neuronal excitability in the nucleus accumbens and behavioral responses to psychostimulants and opioids. Addiction Biology. e12823. PMID 31441201 DOI: 10.1111/adb.12823  0.76
2019 Pinkerton AB, Peddibhotla S, Yamamoto F, Slosky L, Bai Y, Maloney PR, Hershberger P, Hedrick MP, Falter B, Ardecky RJ, Smith LH, Chung TD, Jackson M, Caron MG, Barak LS. Discovery of b-Arrestin Biased, Orally Bioavailable and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31390201 DOI: 10.1021/acs.jmedchem.9b00340  0.8
2019 Martini ML, Ray C, Yu X, Liu J, Pogorelov V, Wetsel WC, Huang XP, McCorvy J, Caron MG, Jin J. Designing Functionally Selective Non-Catechol Dopamine D1 Receptor Agonists with Potent In Vivo Antiparkinsonian Activity. Acs Chemical Neuroscience. PMID 31387346 DOI: 10.1021/acschemneuro.9b00410  0.76
2019 Israelyan N, Del Colle A, Li Z, Park Y, Xing A, Jacobsen JPR, Luna RA, Jensen DD, Madra M, Saurman V, Rahim R, Latorre R, Law K, Carson W, Bunnett NW, ... Caron MG, et al. Effects of Serotonin and Slow-release 5-HTP on Gastrointestinal Motility in a Mouse Model of Depression. Gastroenterology. PMID 31071306 DOI: 10.1053/j.gastro.2019.04.022  0.52
2019 Jacobsen JPR, Oh A, Bangle R, Roberts W, Royer EL, Modesto N, Windermere S, Yi Z, Vernon R, Cajina M, Urs NM, Snyder JC, Nicholls P, Sachs BD, Caron MG. Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31035282 DOI: 10.1038/s41386-019-0400-1  0.76
2019 Caron MG, Barak LS. A Brief History of the β-Arrestins. Methods in Molecular Biology (Clifton, N.J.). 1957: 3-8. PMID 30919344 DOI: 10.1007/978-1-4939-9158-7_1  0.8
2019 Martini ML, Liu J, Ray C, Yu X, Huang XP, Urs A, Urs NM, McCorvy J, Caron MG, Roth BL, Jin J. Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists. Journal of Medicinal Chemistry. PMID 30875219 DOI: 10.1021/acs.jmedchem.9b00351  0.76
2018 Hultman R, Ulrich K, Sachs BD, Blount C, Carlson DE, Ndubuizu N, Bagot RC, Parise EM, Vu MT, Gallagher NM, Wang J, Silva AJ, Deisseroth K, Mague SD, Caron MG, et al. Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability. Cell. PMID 29502969 DOI: 10.1016/j.cell.2018.02.012  0.72
2018 Pack TF, Orlen MI, Ray C, Peterson SM, Caron MG. The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation. The Journal of Biological Chemistry. PMID 29487132 DOI: 10.1074/jbc.RA117.001300  0.36
2018 Sachs BD, Tran HL, Folse E, Caron MG. Title: Brain-region-specific molecular responses to maternal separation and social defeat stress in mice. Neuroscience. PMID 29341883 DOI: 10.1016/j.neuroscience.2018.01.018  0.72
2017 Rose SJ, Pack TF, Peterson SM, Payne K, Borrelli E, Caron MG. Engineered D2R Variants Reveal the Balanced and Biased Contributions of G-Protein and β-Arrestin to Dopamine-Dependent Functions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29068002 DOI: 10.1038/npp.2017.254  0.56
2017 Toth K, Slosky LM, Pack TF, Urs NM, Boone P, Mao L, Abraham D, Caron MG, Barak LS. Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2. Synapse (New York, N.Y.). PMID 28941296 DOI: 10.1002/syn.22012  0.8
2017 Fakhouri L, Cook CD, Al-Huniti MH, Console-Bram LM, Hurst DP, Spano MBS, Nasrallah DJ, Caron MG, Barak LS, Reggio PH, Abood ME, Croatt MP. Design, synthesis and biological evaluation of GPR55 agonists. Bioorganic & Medicinal Chemistry. PMID 28673732 DOI: 10.1016/j.bmc.2017.06.016  0.8
2017 Zhu L, Rossi M, Cui Y, Lee RJ, Sakamoto W, Perry NA, Urs NM, Caron MG, Gurevich VV, Godlewski G, Kunos G, Chen M, Chen W, Wess J. Hepatic β-arrestin 2 is essential for maintaining euglycemia. The Journal of Clinical Investigation. PMID 28650340 DOI: 10.1172/JCI92913  0.76
2017 Snyder JC, Rochelle LK, Ray C, Pack TF, Bock CB, Lubkov V, Lyerly HK, Waggoner AS, Barak LS, Caron MG. Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled Receptor-5 diminishes cell fitness. The Journal of Biological Chemistry. PMID 28275053 DOI: 10.1074/jbc.M116.756635  0.8
2017 Le Gonidec S, Chaves-Almagro C, Bai Y, Kang HJ, Smith A, Wanecq E, Huang XP, Prats H, Knibiehler B, Roth BL, Barak LS, Caron MG, Valet P, Audigier Y, Masri B. Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28242772 DOI: 10.1096/fj.201601074R  0.8
2017 Zhu L, Almaça J, Dadi PK, Hong H, Sakamoto W, Rossi M, Lee RJ, Vierra NC, Lu H, Cui Y, McMillin SM, Perry NA, Gurevich VV, Lee A, Kuo B, ... ... Caron MG, et al. β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions. Nature Communications. 8: 14295. PMID 28145434 DOI: 10.1038/ncomms14295  0.76
2017 Ray C, Soderblom EJ, Bai Y, Carroll FI, Caron MG, Barak LS. Probing the Allosteric Role of the α5 Subunit of α3β4α5 Nicotinic Acetylcholine Receptors by Functionally Selective Modulators and Ligands. Acs Chemical Biology. PMID 28045487 DOI: 10.1021/acschembio.6b01117  0.8
2016 Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG. Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911814 DOI: 10.1073/pnas.1614347113  0.76
2016 Urs NM, Peterson SM, Caron MG. New Concepts in Dopamine D2 Receptor Biased Signaling and Implications for Schizophrenia Therapy. Biological Psychiatry. PMID 27832841 DOI: 10.1016/j.biopsych.2016.10.011  0.76
2016 Barak LS, Bai Y, Peterson S, Evron T, Urs N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Chung TD, Rodriguiz RM, Wetsel WC, Thomas JB, Hanson GR, Pinkerton AB, ... Caron MG, et al. ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse. Acs Chemical Biology. PMID 27119457 DOI: 10.1021/acschembio.6b00291  1
2016 Jacobsen JP, Rudder ML, Roberts W, Royer EL, Robinson TJ, Oh A, Spasojevic I, Sachs BD, Caron MG. SSRI Augmentation by 5-Hydroxytryptophan Slow-Release: Mouse Pharmacodynamic Proof-of-Concept. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26932820 DOI: 10.1038/npp.2016.35  0.72
2016 Meza-Aviña ME, Lingerfelt MA, Console-Bram LM, Gamage TF, Sharir H, Gettys KE, Hurst DP, Kotsikorou E, Shore DM, Caron MG, Rao N, Barak LS, Abood ME, Reggio PH, Croatt MP. Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones. Bioorganic & Medicinal Chemistry Letters. PMID 26916440 DOI: 10.1016/j.bmcl.2016.02.030  0.8
2015 Snyder JC, Pack TF, Rochelle LK, Chakraborty SK, Zhang M, Eaton AW, Bai Y, Ernst LA, Barak LS, Waggoner AS, Caron MG. A rapid and affordable screening platform for membrane protein trafficking. Bmc Biology. 13: 107. PMID 26678094 DOI: 10.1186/s12915-015-0216-3  1
2015 Peterson SM, Pack TF, Caron MG. Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity. Plos One. 10: e0141637. PMID 26516769 DOI: 10.1371/journal.pone.0141637  1
2015 Park SM, Chen M, Schmerberg CM, Dulman RS, Rodriguiz RM, Caron MG, Jin J, Wetsel WC. Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-like Behavior in Hypoglutamatergic Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26129680 DOI: 10.1038/npp.2015.196  1
2015 Peterson SM, Pack TF, Wilkins AD, Urs NM, Urban DJ, Bass CE, Lichtarge O, Caron MG. Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor. Proceedings of the National Academy of Sciences of the United States of America. 112: 7097-102. PMID 25964346 DOI: 10.1073/pnas.1502742112  1
2015 Urs NM, Bido S, Peterson SM, Daigle TL, Bass CE, Gainetdinov RR, Bezard E, Caron MG. Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 112: E2517-26. PMID 25918399 DOI: 10.1073/pnas.1502740112  1
2015 Gao Y, Peterson S, Masri B, Hougland MT, Adham N, Gyertyán I, Kiss B, Caron MG, El-Mallakh RS. Cariprazine exerts antimanic properties and interferes with dopamine D2 receptor β-arrestin interactions. Pharmacology Research & Perspectives. 3: e00073. PMID 25692006 DOI: 10.1002/prp2.73  0.64
2015 Sidor MM, Spencer SM, Dzirasa K, Parekh PK, Tye KM, Warden MR, Arey RN, Enwright JF, Jacobsen JP, Kumar S, Remillard EM, Caron MG, Deisseroth K, McClung CA. Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice. Molecular Psychiatry. PMID 25687774 DOI: 10.1038/mp.2015.8  0.4
2015 Sachs BD, Ni JR, Caron MG. Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress. Proceedings of the National Academy of Sciences of the United States of America. 112: 2557-62. PMID 25675490 DOI: 10.1073/pnas.1416866112  1
2015 Snyder JC, Rochelle LK, Marion S, Lyerly HK, Barak LS, Caron MG. Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions. Journal of Cell Science. 128: 1230-40. PMID 25653388 DOI: 10.1242/jcs.166322  1
2015 Sachs BD, Rodriguiz RM, Tran HL, Iyer A, Wetsel WC, Caron MG. Serotonin deficiency alters susceptibility to the long-term consequences of adverse early life experience. Psychoneuroendocrinology. 53: 69-81. PMID 25602134 DOI: 10.1016/j.psyneuen.2014.12.019  1
2015 Sachs BD, Caron MG. Chronic fluoxetine increases extra-hippocampal neurogenesis in adult mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25583694 DOI: 10.1093/ijnp/pyu029  1
2015 Sidor MM, Spencer SM, Dzirasa K, Parekh PK, Tye KM, Warden MR, Arey RN, Enwright JF, Jacobsen JP, Kumar S, Remillard EM, Caron MG, Deisseroth K, McClung CA. Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice. Molecular Psychiatry. 5. PMID 25560763 DOI: 10.1038/mp.2014.167  1
2015 Burczyk M, Burkhalter MD, Blätte T, Matysik S, Caron MG, Barak LS, Philipp M. Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2. Biochemistry. 54: 765-75. PMID 25555130 DOI: 10.1021/bi501061h  1
2015 Sutton LP, Caron MG. Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine Neuropharmacology. 99: 610-619. DOI: 10.1016/j.neuropharm.2015.08.024  1
2014 Evron T, Peterson SM, Urs NM, Bai Y, Rochelle LK, Caron MG, Barak LS. G Protein and β-arrestin signaling bias at the ghrelin receptor. The Journal of Biological Chemistry. 289: 33442-55. PMID 25261469 DOI: 10.1074/jbc.M114.581397  1
2014 Philipp M, Berger IM, Just S, Caron MG. Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development. The Journal of Biological Chemistry. 289: 26119-30. PMID 25104355 DOI: 10.1074/jbc.M114.551952  1
2014 Wang C, Wu H, Evron T, Vardy E, Han GW, Huang XP, Hufeisen SJ, Mangano TJ, Urban DJ, Katritch V, Cherezov V, Caron MG, Roth BL, Stevens RC. Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nature Communications. 5: 4355. PMID 25008467 DOI: 10.1038/ncomms5355  1
2014 Jacobsen JP, Plenge P, Sachs BD, Pehrson AL, Cajina M, Du Y, Roberts W, Rudder ML, Dalvi P, Robinson TJ, O'Neill SP, Khoo KS, Morillo CS, Zhang X, Caron MG. The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse. Psychopharmacology. 231: 4527-40. PMID 24810106 DOI: 10.1007/s00213-014-3595-1  1
2014 Daigle TL, Ferris MJ, Gainetdinov RR, Sotnikova TD, Urs NM, Jones SR, Caron MG. Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2450-62. PMID 24776686 DOI: 10.1038/npp.2014.97  1
2014 Urs NM, Nicholls PJ, Caron MG. Integrated approaches to understanding antipsychotic drug action at GPCRs. Current Opinion in Cell Biology. 27: 56-62. PMID 24680431 DOI: 10.1016/j.ceb.2013.11.002  1
2014 Marion S, Urs NM, Peterson SM, Sotnikova TD, Beaulieu JM, Gainetdinov RR, Caron MG. Dopamine D2 receptor relies upon PPM/PP2C protein phosphatases to dephosphorylate huntingtin protein. The Journal of Biological Chemistry. 289: 11715-24. PMID 24619418 DOI: 10.1074/jbc.M113.544312  1
2014 Sachs BD, Ni JR, Caron MG. Sex differences in response to chronic mild stress and congenital serotonin deficiency. Psychoneuroendocrinology. 40: 123-9. PMID 24485484 DOI: 10.1016/j.psyneuen.2013.11.008  1
2014 Hershberger PM, Hedrick MP, Peddibhotla S, Mangravita-Novo A, Gosalia P, Li Y, Gray W, Vicchiarelli M, Smith LH, Chung TD, Thomas JB, Caron MG, Pinkerton AB, Barak LS, Roth GP. Imidazole-derived agonists for the neurotensin 1 receptor. Bioorganic & Medicinal Chemistry Letters. 24: 262-7. PMID 24332089 DOI: 10.1016/j.bmcl.2013.11.026  1
2014 Sachs BD, Salahi AA, Caron MG. Congenital brain serotonin deficiency leads to reduced ethanol sensitivity and increased ethanol consumption in mice. Neuropharmacology. 77: 177-84. PMID 24067926 DOI: 10.1016/j.neuropharm.2013.09.010  1
2014 Snyder JC, Rochelle LK, Barak LS, Caron MG. Correction: The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment (PLoS ONE) Plos One. 9. DOI: 10.1371/annotation/7f83735d-53d4-42f3-b3b2-b05dd5db059c  1
2013 Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, ... ... Caron MG, et al. Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor. Acs Medicinal Chemistry Letters. 4: 846-851. PMID 24611085 DOI: 10.1021/ml400176n  1
2013 Snyder JC, Rochelle LK, Barak LS, Caron MG. The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment. Plos One. 8: e84476. PMID 24386388 DOI: 10.1371/journal.pone.0084476  1
2013 Kotsikorou E, Sharir H, Shore DM, Hurst DP, Lynch DL, Madrigal KE, Heynen-Genel S, Milan LB, Chung TD, Seltzman HH, Bai Y, Caron MG, Barak LS, Croatt MP, Abood ME, et al. Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry. 52: 9456-69. PMID 24274581 DOI: 10.1021/bi4008885  1
2013 Calipari ES, Ferris MJ, Salahpour A, Caron MG, Jones SR. Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression. Nature Communications. 4: 2720. PMID 24193139 DOI: 10.1038/ncomms3720  1
2013 Jørgensen CV, Jacobsen JP, Caron MG, Klein AB, Knudsen GM, Mikkelsen JD. Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice. Neuroscience Letters. 555: 118-22. PMID 24055299 DOI: 10.1016/j.neulet.2013.08.073  1
2013 Min C, Zheng M, Zhang X, Caron MG, Kim KM. Novel roles for β-arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine D3 receptors. British Journal of Pharmacology. 170: 1112-29. PMID 23992580 DOI: 10.1111/bph.12357  1
2013 Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M. Grk5l controls heart development by limiting mTOR signaling during symmetry breaking. Cell Reports. 4: 625-32. PMID 23972986 DOI: 10.1016/j.celrep.2013.07.036  1
2013 Gregory KJ, Herman EJ, Ramsey AJ, Hammond AS, Byun NE, Stauffer SR, Manka JT, Jadhav S, Bridges TM, Weaver CD, Niswender CM, Steckler T, Drinkenburg WH, Ahnaou A, Lavreysen H, ... ... Caron MG, et al. N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement. The Journal of Pharmacology and Experimental Therapeutics. 347: 438-57. PMID 23965381 DOI: 10.1124/jpet.113.206623  1
2013 Sachs BD, Jacobsen JP, Thomas TL, Siesser WB, Roberts WL, Caron MG. The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine. Translational Psychiatry. 3: e291. PMID 23942622 DOI: 10.1038/tp.2013.65  1
2013 Barak LS, Bai Y, Snyder JC, Wang J, Chen W, Caron MG. Triphenylmethane dye activation of beta-arrestin. Biochemistry. 52: 5403-14. PMID 23865508 DOI: 10.1021/bi400217r  1
2013 Philipp M, Evron T, Caron MG. The role of arrestins in development. Progress in Molecular Biology and Translational Science. 118: 225-42. PMID 23764056 DOI: 10.1016/B978-0-12-394440-5.00009-7  1
2013 Sachs BD, Rodriguiz RM, Siesser WB, Kenan A, Royer EL, Jacobsen JP, Wetsel WC, Caron MG. The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2081-94. PMID 23672796 DOI: 10.1017/S1461145713000321  1
2013 Thakur GA, Bajaj S, Paronis C, Peng Y, Bowman AL, Barak LS, Caron MG, Parrish D, Deschamps JR, Makriyannis A. Novel adamantyl cannabinoids as CB1 receptor probes. Journal of Medicinal Chemistry. 56: 3904-21. PMID 23621789 DOI: 10.1021/jm4000775  1
2013 Dzirasa K, Kumar S, Sachs BD, Caron MG, Nicolelis MA. Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4505-13. PMID 23467366 DOI: 10.1523/JNEUROSCI.4891-12.2013  1
2013 Snyder JC, Rochelle LK, Lyerly HK, Caron MG, Barak LS. Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network. The Journal of Biological Chemistry. 288: 10286-97. PMID 23439653 DOI: 10.1074/jbc.M112.447540  1
2013 Siesser WB, Sachs BD, Ramsey AJ, Sotnikova TD, Beaulieu JM, Zhang X, Caron MG, Gainetdinov RR. Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice. Acs Chemical Neuroscience. 4: 84-8. PMID 23336047 DOI: 10.1021/cn300127h  1
2013 Farrell MS, Pei Y, Wan Y, Yadav PN, Daigle TL, Urban DJ, Lee HM, Sciaky N, Simmons A, Nonneman RJ, Huang XP, Hufeisen SJ, Guettier JM, Moy SS, Wess J, ... Caron MG, et al. A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 854-62. PMID 23303063 DOI: 10.1038/npp.2012.251  1
2013 Hara MR, Sachs BD, Caron MG, Lefkowitz RJ. Pharmacological blockade of a β(2)AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model. Cell Cycle (Georgetown, Tex.). 12: 219-24. PMID 23287463 DOI: 10.4161/cc.23368  1
2013 Evron T, Urs NM, Sutton L, Bai Y, Caron MG, Barak LS. β-arrestin Regulation of Ghrelin Signaling in modulating Addictive Behavior Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 184. DOI: 10.1016/B978-0-12-800044-1.00167-7  1
2013 Sassano MF, Allen JA, Jin J, Setola V, Wetsel WC, Caron MG, Roth BL. D2 Functionally Selective Ligands: Novel Therapeutics? Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 105. DOI: 10.1016/B978-0-12-800044-1.00091-X  1
2013 Urs NM, Daigle TL, Ting J, Caron MG. Targeting Beta-Arrestin Dependent Signaling in the Treatment of Parkinson's Disease Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 103-104. DOI: 10.1016/B978-0-12-800044-1.00090-8  1
2013 Caron MG, Urs NM, Snyder JC, Peterson SM. Integrated Approaches to Understand the Actions of GPCRs: The b-Arrestin-Dependent D2R Mediated Signaling Through Akt/GSK3 Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 99-100. DOI: 10.1016/B978-0-12-800044-1.00086-6  1
2012 Wong P, Chang CC, Marx CE, Caron MG, Wetsel WC, Zhang X. Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice. Plos One. 7: e51455. PMID 23240026 DOI: 10.1371/journal.pone.0051455  1
2012 Urs NM, Snyder JC, Jacobsen JP, Peterson SM, Caron MG. Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action. Proceedings of the National Academy of Sciences of the United States of America. 109: 20732-7. PMID 23188793 DOI: 10.1073/pnas.1215489109  1
2012 Daigle TL, Caron MG. Elimination of GRK2 from cholinergic neurons reduces behavioral sensitivity to muscarinic receptor activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11461-6. PMID 22895728 DOI: 10.1523/JNEUROSCI.2234-12.2012  1
2012 Jacobsen JP, Medvedev IO, Caron MG. The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2444-59. PMID 22826344 DOI: 10.1098/rstb.2012.0109  1
2012 Anzalone A, Lizardi-Ortiz JE, Ramos M, De Mei C, Hopf FW, Iaccarino C, Halbout B, Jacobsen J, Kinoshita C, Welter M, Caron MG, Bonci A, Sulzer D, Borrelli E. Dual control of dopamine synthesis and release by presynaptic and postsynaptic dopamine D2 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9023-34. PMID 22745501 DOI: 10.1523/JNEUROSCI.0918-12.2012  1
2012 Frankowski KJ, Hedrick MP, Gosalia P, Li K, Shi S, Whipple D, Ghosh P, Prisinzano TE, Schoenen FJ, Su Y, Vasile S, Sergienko E, Gray W, Hariharan S, Milan L, ... ... Caron MG, et al. Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. Acs Chemical Neuroscience. 3: 221-236. PMID 22737280 DOI: 10.1021/cn200128x  1
2012 Kile BM, Walsh PL, McElligott ZA, Bucher ES, Guillot TS, Salahpour A, Caron MG, Wightman RM. Optimizing the Temporal Resolution of Fast-Scan Cyclic Voltammetry. Acs Chemical Neuroscience. 3: 285-292. PMID 22708011 DOI: 10.1021/cn200119u  1
2012 Revel FG, Moreau JL, Gainetdinov RR, Ferragud A, Velázquez-Sánchez C, Sotnikova TD, Morairty SR, Harmeier A, Groebke Zbinden K, Norcross RD, Bradaia A, Kilduff TS, Biemans B, Pouzet B, Caron MG, et al. Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics. Biological Psychiatry. 72: 934-42. PMID 22705041 DOI: 10.1016/j.biopsych.2012.05.014  1
2012 Managò F, Espinoza S, Salahpour A, Sotnikova TD, Caron MG, Premont RT, Gainetdinov RR. The role of GRK6 in animal models of Parkinson's disease and L-DOPA treatment. Scientific Reports. 2: 301. PMID 22393477 DOI: 10.1038/srep00301  1
2012 Salahpour A, Caron MG. Food for thought: the physiological relevance of ghrelin and dopamine D2 receptor heterodimerization in the regulation of appetite. Neuron. 73: 210-1. PMID 22284175 DOI: 10.1016/j.neuron.2012.01.004  1
2012 Evron T, Daigle TL, Caron MG. GRK2: multiple roles beyond G protein-coupled receptor desensitization. Trends in Pharmacological Sciences. 33: 154-64. PMID 22277298 DOI: 10.1016/j.tips.2011.12.003  1
2012 Zhong H, Sánchez C, Caron MG. Consideration of allosterism and interacting proteins in the physiological functions of the serotonin transporter. Biochemical Pharmacology. 83: 435-42. PMID 21983034 DOI: 10.1016/j.bcp.2011.09.020  1
2012 Jacobsen JP, Siesser WB, Sachs BD, Peterson S, Cools MJ, Setola V, Folgering JH, Flik G, Caron MG. Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice. Molecular Psychiatry. 17: 694-704. PMID 21537332 DOI: 10.1038/mp.2011.50  1
2012 Meck WH, Cheng RK, MacDonald CJ, Gainetdinov RR, Caron MG, Cevik MÖ. Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice. Neuropharmacology. 62: 1221-9. PMID 21296093 DOI: 10.1016/j.neuropharm.2011.01.042  1
2012 Peterson SM, Urs N, Caron MG. Dopamine Receptors Primer On the Autonomic Nervous System. 67-70. DOI: 10.1016/B978-0-12-386525-0.00013-5  1
2011 Guzman MS, De Jaeger X, Raulic S, Souza IA, Li AX, Schmid S, Menon RS, Gainetdinov RR, Caron MG, Bartha R, Prado VF, Prado MA. Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission. Plos Biology. 9: e1001194. PMID 22087075 DOI: 10.1371/journal.pbio.1001194  1
2011 Daigle TL, Wetsel WC, Caron MG. Opposite function of dopamine D1 and N-methyl-D-aspartate receptors in striatal cannabinoid-mediated signaling. The European Journal of Neuroscience. 34: 1378-89. PMID 22034973 DOI: 10.1111/j.1460-9568.2011.07874.x  1
2011 Marder SR, Roth B, Sullivan PF, Scolnick EM, Nestler EJ, Geyer MA, Welnberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, ... ... Caron MG, et al. Advancing drug discovery for schizophrenia. Annals of the New York Academy of Sciences. 1236: 30-43. PMID 22032400 DOI: 10.1111/j.1749-6632.2011.06216.x  1
2011 Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, ... Caron MG, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/pnas.1104807108  1
2011 Herrmann R, Heflin SJ, Hammond T, Lee B, Wang J, Gainetdinov RR, Caron MG, Eggers ED, Frishman LJ, McCall MA, Arshavsky VY. Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA. Neuron. 72: 101-10. PMID 21982372 DOI: 10.1016/j.neuron.2011.07.030  1
2011 Espinoza S, Salahpour A, Masri B, Sotnikova TD, Messa M, Barak LS, Caron MG, Gainetdinov RR. Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor. Molecular Pharmacology. 80: 416-25. PMID 21670104 DOI: 10.1124/mol.111.073304  1
2011 Evron T, Philipp M, Lu J, Meloni AR, Burkhalter M, Chen W, Caron MG. Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling. The Journal of Biological Chemistry. 286: 27676-86. PMID 21659505 DOI: 10.1074/jbc.M111.234666  1
2011 Jocoy EL, André VM, Cummings DM, Rao SP, Wu N, Ramsey AJ, Caron MG, Cepeda C, Levine MS. Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum. Frontiers in Systems Neuroscience. 5: 28. PMID 21617735 DOI: 10.3389/fnsys.2011.00028  1
2011 Kotsikorou E, Madrigal KE, Hurst DP, Sharir H, Lynch DL, Heynen-Genel S, Milan LB, Chung TD, Seltzman HH, Bai Y, Caron MG, Barak L, Abood ME, Reggio PH. Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry. 50: 5633-47. PMID 21534610 DOI: 10.1021/bi200010k  1
2011 Revel FG, Moreau JL, Gainetdinov RR, Bradaia A, Sotnikova TD, Mory R, Durkin S, Zbinden KG, Norcross R, Meyer CA, Metzler V, Chaboz S, Ozmen L, Trube G, Pouzet B, ... ... Caron MG, et al. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8485-90. PMID 21525407 DOI: 10.1073/pnas.1103029108  1
2011 Soderblom EJ, Philipp M, Thompson JW, Caron MG, Moseley MA. Quantitative label-free phosphoproteomics strategy for multifaceted experimental designs. Analytical Chemistry. 83: 3758-64. PMID 21491946 DOI: 10.1021/ac200213b  1
2011 Ramsey AJ, Milenkovic M, Oliveira AF, Escobedo-Lozoya Y, Seshadri S, Salahpour A, Sawa A, Yasuda R, Caron MG. Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 5795-800. PMID 21436042 DOI: 10.1073/pnas.1012621108  1
2011 Martins-Silva C, De Jaeger X, Guzman MS, Lima RD, Santos MS, Kushmerick C, Gomez MV, Caron MG, Prado MA, Prado VF. Novel strains of mice deficient for the vesicular acetylcholine transporter: insights on transcriptional regulation and control of locomotor behavior. Plos One. 6: e17611. PMID 21423695 DOI: 10.1371/journal.pone.0017611  1
2011 Mathurin K, Gallant MA, Germain P, Allard-Chamard H, Brisson J, Iorio-Morin C, de Brum Fernandes A, Caron MG, Laporte SA, Parent JL. An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production. The Journal of Biological Chemistry. 286: 2696-706. PMID 21112970 DOI: 10.1074/jbc.M110.178277  1
2011 Omenetti A, Yang L, Gainetdinov RR, Guy CD, Choi SS, Chen W, Caron MG, Diehl AM. Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G303-15. PMID 21071507 DOI: 10.1152/ajpgi.00368.2010  1
2011 Urs NM, Daigle TL, Caron MG. A dopamine D1 receptor-dependent β-arrestin signaling complex potentially regulates morphine-induced psychomotor activation but not reward in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 551-8. PMID 20980993 DOI: 10.1038/npp.2010.186  1
2011 Zhang X, Nicholls PJ, Laje G, Sotnikova TD, Gainetdinov RR, Albert PR, Rajkowska G, Stockmeier CA, Speer MC, Steffens DC, Austin MC, McMahon FJ, Krishnan KR, Garcia-Blanco MA, Caron MG. A functional alternative splicing mutation in human tryptophan hydroxylase-2. Molecular Psychiatry. 16: 1169-76. PMID 20856248 DOI: 10.1038/mp.2010.99  1
2010 Li Z, Caron MG, Blakely RD, Margolis KG, Gershon MD. Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16730-40. PMID 21148012 DOI: 10.1523/JNEUROSCI.2276-10.2010  1
2010 Sotnikova TD, Beaulieu JM, Espinoza S, Masri B, Zhang X, Salahpour A, Barak LS, Caron MG, Gainetdinov RR. The dopamine metabolite 3-methoxytyramine is a neuromodulator. Plos One. 5: e13452. PMID 20976142 DOI: 10.1371/journal.pone.0013452  1
2010 Kenakin T, Agnati LF, Caron M, Fredholm B, Guidoli D, Kobilka B, Lefkowitz RW, Lohse M, Woods A, Fuxe K. International Workshop at the Nobel Forum, Karolinska Institutet on G protein-coupled receptors: finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached? Journal of Receptor and Signal Transduction Research. 30: 284-6. PMID 20858022 DOI: 10.3109/10799893.2010.512438  1
2010 Zhao P, Sharir H, Kapur A, Cowan A, Geller EB, Adler MW, Seltzman HH, Reggio PH, Heynen-Genel S, Sauer M, Chung TD, Bai Y, Chen W, Caron MG, Barak LS, et al. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Molecular Pharmacology. 78: 560-8. PMID 20826425 DOI: 10.1124/mol.110.066746  1
2010 Siesser WB, Zhang X, Jacobsen JP, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice. Neuroscience Letters. 481: 6-11. PMID 20600620 DOI: 10.1016/j.neulet.2010.06.035  1
2010 Dzirasa K, Phillips HW, Sotnikova TD, Salahpour A, Kumar S, Gainetdinov RR, Caron MG, Nicolelis MA. Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6387-97. PMID 20445065 DOI: 10.1523/JNEUROSCI.0764-10.2010  1
2010 Bowton E, Saunders C, Erreger K, Sakrikar D, Matthies HJ, Sen N, Jessen T, Colbran RJ, Caron MG, Javitch JA, Blakely RD, Galli A. Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6048-57. PMID 20427663 DOI: 10.1523/JNEUROSCI.5094-09.2010  1
2010 Lara A, Damasceno DD, Pires R, Gros R, Gomes ER, Gavioli M, Lima RF, Guimarães D, Lima P, Bueno CR, Vasconcelos A, Roman-Campos D, Menezes CA, Sirvente RA, Salemi VM, ... ... Caron MG, et al. Dysautonomia due to reduced cholinergic neurotransmission causes cardiac remodeling and heart failure. Molecular and Cellular Biology. 30: 1746-56. PMID 20123977 DOI: 10.1128/MCB.00996-09  1
2010 Caron MG, Gainetdinov RR. Role of Dopamine Transporters in Neuronal Homeostasis Dopamine Handbook. DOI: 10.1093/acprof:oso/9780195373035.003.0007  1
2009 Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W. G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. The Journal of Biological Chemistry. 284: 35040-8. PMID 19801552 DOI: 10.1074/jbc.M109.047456  1
2009 Kapur A, Zhao P, Sharir H, Bai Y, Caron MG, Barak LS, Abood ME. Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands. The Journal of Biological Chemistry. 284: 29817-27. PMID 19723626 DOI: 10.1074/jbc.M109.050187  1
2009 Haenisch B, Bilkei-Gorzo A, Caron MG, Bönisch H. Knockout of the norepinephrine transporter and pharmacologically diverse antidepressants prevent behavioral and brain neurotrophin alterations in two chronic stress models of depression. Journal of Neurochemistry. 111: 403-16. PMID 19694905 DOI: 10.1111/j.1471-4159.2009.06345.x  1
2009 de Castro BM, De Jaeger X, Martins-Silva C, Lima RD, Amaral E, Menezes C, Lima P, Neves CM, Pires RG, Gould TW, Welch I, Kushmerick C, Guatimosim C, Izquierdo I, Cammarota M, ... ... Caron MG, et al. The vesicular acetylcholine transporter is required for neuromuscular development and function. Molecular and Cellular Biology. 29: 5238-50. PMID 19635813 DOI: 10.1128/MCB.00245-09  1
2009 Dzirasa K, Ramsey AJ, Takahashi DY, Stapleton J, Potes JM, Williams JK, Gainetdinov RR, Sameshima K, Caron MG, Nicolelis MA. Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8215-24. PMID 19553461 DOI: 10.1523/JNEUROSCI.1773-09.2009  1
2009 Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL. PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7124-36. PMID 19494135 DOI: 10.1523/JNEUROSCI.1090-09.2009  1
2009 Singer D, Camargo SM, Huggel K, Romeo E, Danilczyk U, Kuba K, Chesnov S, Caron MG, Penninger JM, Verrey F. Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3. The Journal of Biological Chemistry. 284: 19953-60. PMID 19478081 DOI: 10.1074/jbc.M109.011171  1
2009 Caron MG, Wightman RM. "To learn, you must pay attention." Molecular insights into teachers' wisdom. Proceedings of the National Academy of Sciences of the United States of America. 106: 7267-8. PMID 19416916 DOI: 10.1073/pnas.0903306106  1
2009 Sotnikova TD, Caron MG, Gainetdinov RR. Trace amine-associated receptors as emerging therapeutic targets. Molecular Pharmacology. 76: 229-35. PMID 19389919 DOI: 10.1124/mol.109.055970  1
2009 Dzirasa K, Santos LM, Ribeiro S, Stapleton J, Gainetdinov RR, Caron MG, Nicolelis MA. Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep. Plos One. 4: e5238. PMID 19381303 DOI: 10.1371/journal.pone.0005238  1
2009 Fuentes R, Petersson P, Siesser WB, Caron MG, Nicolelis MA. Spinal cord stimulation restores locomotion in animal models of Parkinson's disease. Science (New York, N.Y.). 323: 1578-82. PMID 19299613 DOI: 10.1126/science.1164901  1
2009 Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/nchembio0309-131  1
2009 Philipp M, Caron MG. Hedgehog signaling: is Smo a G protein-coupled receptor? Current Biology : Cb. 19: R125-7. PMID 19211052 DOI: 10.1016/j.cub.2008.12.010  0.44
2009 Kocerha J, Faghihi MA, Lopez-Toledano MA, Huang J, Ramsey AJ, Caron MG, Sales N, Willoughby D, Elmen J, Hansen HF, Orum H, Kauppinen S, Kenny PJ, Wahlestedt C. MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 106: 3507-12. PMID 19196972 DOI: 10.1073/pnas.0805854106  1
2009 Ghisi V, Ramsey AJ, Masri B, Gainetdinov RR, Caron MG, Salahpour A. Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter. Cellular Signalling. 21: 87-94. PMID 18929645 DOI: 10.1016/j.cellsig.2008.09.011  1
2009 Beaulieu JM, Gainetdinov RR, Caron MG. Akt/GSK3 signaling in the action of psychotropic drugs. Annual Review of Pharmacology and Toxicology. 49: 327-47. PMID 18928402 DOI: 10.1146/annurev.pharmtox.011008.145634  1
2009 de Castro BM, Pereira GS, Magalhães V, Rossato JI, De Jaeger X, Martins-Silva C, Leles B, Lima P, Gomez MV, Gainetdinov RR, Caron MG, Izquierdo I, Cammarota M, Prado VF, Prado MA. Reduced expression of the vesicular acetylcholine transporter causes learning deficits in mice. Genes, Brain, and Behavior. 8: 23-35. PMID 18778400 DOI: 10.1111/j.1601-183X.2008.00439.x  1
2008 Beaulieu JM, Caron MG. Looking at lithium: molecular moods and complex behaviour. Molecular Interventions. 8: 230-41. PMID 19015387 DOI: 10.1124/mi.8.5.8  1
2008 Tiruchinapalli DM, Caron MG, Keene JD. Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain. Journal of Neurochemistry. 107: 1529-43. PMID 19014379 DOI: 10.1111/j.1471-4159.2008.05718.x  1
2008 Philipp M, Fralish GB, Meloni AR, Chen W, MacInnes AW, Barak LS, Caron MG. Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase. Molecular Biology of the Cell. 19: 5478-89. PMID 18815277 DOI: 10.1091/mbc.E08-05-0448  1
2008 Masri B, Salahpour A, Didriksen M, Ghisi V, Beaulieu JM, Gainetdinov RR, Caron MG. Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics. Proceedings of the National Academy of Sciences of the United States of America. 105: 13656-61. PMID 18768802 DOI: 10.1073/pnas.0803522105  1
2008 Perona MT, Waters S, Hall FS, Sora I, Lesch KP, Murphy DL, Caron M, Uhl GR. Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions. Behavioural Pharmacology. 19: 566-74. PMID 18690111 DOI: 10.1097/FBP.0b013e32830cd80f  1
2008 Powell SB, Young JW, Ong JC, Caron MG, Geyer MA. Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behavioural Pharmacology. 19: 562-5. PMID 18690110 DOI: 10.1097/FBP.0b013e32830dc110  1
2008 Sotnikova TD, Zorina OI, Ghisi V, Caron MG, Gainetdinov RR. Trace amine associated receptor 1 and movement control. Parkinsonism & Related Disorders. 14: S99-102. PMID 18585080 DOI: 10.1016/j.parkreldis.2008.04.006  1
2008 Barak LS, Salahpour A, Zhang X, Masri B, Sotnikova TD, Ramsey AJ, Violin JD, Lefkowitz RJ, Caron MG, Gainetdinov RR. Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor. Molecular Pharmacology. 74: 585-94. PMID 18524885 DOI: 10.1124/mol.108.048884  1
2008 de Araujo IE, Oliveira-Maia AJ, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis MA, Simon SA. Food reward in the absence of taste receptor signaling. Neuron. 57: 930-41. PMID 18367093 DOI: 10.1016/j.neuron.2008.01.032  1
2008 Salahpour A, Ramsey AJ, Medvedev IO, Kile B, Sotnikova TD, Holmstrand E, Ghisi V, Nicholls PJ, Wong L, Murphy K, Sesack SR, Wightman RM, Gainetdinov RR, Caron MG. Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 105: 4405-10. PMID 18347339 DOI: 10.1073/pnas.0707646105  1
2008 Murphy KL, Zhang X, Gainetdinov RR, Beaulieu JM, Caron MG. A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression. The Journal of Biological Chemistry. 283: 13216-24. PMID 18339632 DOI: 10.1074/jbc.M706749200  1
2008 Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Cools MJ, Wetsel WC, Gainetdinov RR, Caron MG. Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. Proceedings of the National Academy of Sciences of the United States of America. 105: 1333-8. PMID 18212115 DOI: 10.1073/pnas.0711496105  1
2008 Beaulieu JM, Marion S, Rodriguiz RM, Medvedev IO, Sotnikova TD, Ghisi V, Wetsel WC, Lefkowitz RJ, Gainetdinov RR, Caron MG. A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell. 132: 125-36. PMID 18191226 DOI: 10.1016/j.cell.2007.11.041  1
2008 Ramsey AJ, Laakso A, Cyr M, Sotnikova TD, Salahpour A, Medvedev IO, Dykstra LA, Gainetdinov RR, Caron MG. Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2701-14. PMID 18185498 DOI: 10.1038/sj.npp.1301663  1
2008 Jensen NH, Rodriguiz RM, Caron MG, Wetsel WC, Rothman RB, Roth BL. N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2303-12. PMID 18059438 DOI: 10.1038/sj.npp.1301646  1
2008 Kim KM, Caron MG. Complementary roles of the DRY motif and C-terminus tail of GPCRS for G protein coupling and beta-arrestin interaction. Biochemical and Biophysical Research Communications. 366: 42-7. PMID 18036556 DOI: 10.1016/j.bbrc.2007.11.055  1
2008 Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Wetsel WC, Gainetdinov RR, Caron MG. Reply to Belmaker et al.: GSK3β haploinsufficiency results in lithium-like effects in the forced-swim test Proceedings of the National Academy of Sciences of the United States of America. 105: E24. DOI: 10.1073/pnas.0803026105  1
2008 de Araujo IE, Oliveira-Maia AJ, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis ML, Simon SA. Food Reward in the Absence of Taste Receptor Signaling (DOI:10.1016/j.neuron.2008.01.032) Neuron. 58: 295. DOI: 10.1016/j.neuron.2008.04.003  1
2007 Fukui M, Rodriguiz RM, Zhou J, Jiang SX, Phillips LE, Caron MG, Wetsel WC. Vmat2 heterozygous mutant mice display a depressive-like phenotype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10520-9. PMID 17898223 DOI: 10.1523/JNEUROSCI.4388-06.2007  1
2007 Cho EY, Cho DI, Park JH, Kurose H, Caron MG, Kim KM. Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine D3 receptor. Molecular Endocrinology (Baltimore, Md.). 21: 2242-54. PMID 17536008 DOI: 10.1210/me.2007-0202  0.52
2007 Marion S, Fralish GB, Laporte S, Caron MG, Barak LS. N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins. The Journal of Biological Chemistry. 282: 18937-44. PMID 17456469 DOI: 10.1074/jbc.M700090200  0.8
2007 Zhang J, Vinuela A, Neely MH, Hallett PJ, Grant SG, Miller GM, Isacson O, Caron MG, Yao WD. Inhibition of the dopamine D1 receptor signaling by PSD-95. The Journal of Biological Chemistry. 282: 15778-89. PMID 17369255 DOI: 10.1074/jbc.M611485200  1
2007 Beaulieu JM, Gainetdinov RR, Caron MG. The Akt-GSK-3 signaling cascade in the actions of dopamine. Trends in Pharmacological Sciences. 28: 166-72. PMID 17349698 DOI: 10.1016/j.tips.2007.02.006  1
2007 Vincent SG, Waddell AE, Caron MG, Walker JK, Fisher JT. A murine model of hyperdopaminergic state displays altered respiratory control. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1463-71. PMID 17255472 DOI: 10.1096/fj.06-7248com  1
2007 Beaulieu JM, Tirotta E, Sotnikova TD, Masri B, Salahpour A, Gainetdinov RR, Borrelli E, Caron MG. Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 881-5. PMID 17251429 DOI: 10.1523/JNEUROSCI.5074-06.2007  1
2007 Costa RM, Gutierrez R, de Araujo IE, Coelho MR, Kloth AD, Gainetdinov RR, Caron MG, Nicolelis MA, Simon SA. Dopamine levels modulate the updating of tastant values. Genes, Brain, and Behavior. 6: 314-20. PMID 16848782 DOI: 10.1111/j.1601-183X.2006.00257.x  1
2007 Salahpour A, Medvedev IO, Beaulieu JM, Gainetdinov RR, Caron MG. Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals. Biological Psychiatry. 61: 65-9. PMID 16712807 DOI: 10.1016/j.biopsych.2006.03.020  1
2006 Caron MG, Gainetdinov RR. Dopamine: from pharmacology to molecular biology and back. Wiener Klinische Wochenschrift. 118: 565-8. PMID 17136328 DOI: 10.1007/s00508-006-0735-6  1
2006 Cyr M, Sotnikova TD, Gainetdinov RR, Caron MG. Dopamine enhances motor and neuropathological consequences of polyglutamine expanded huntingtin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2541-3. PMID 17065224 DOI: 10.1096/fj.06-6533fje  1
2006 Costa RM, Lin SC, Sotnikova TD, Cyr M, Gainetdinov RR, Caron MG, Nicolelis MA. Rapid alterations in corticostriatal ensemble coordination during acute dopamine-dependent motor dysfunction. Neuron. 52: 359-69. PMID 17046697 DOI: 10.1016/j.neuron.2006.07.030  1
2006 Dzirasa K, Ribeiro S, Costa R, Santos LM, Lin SC, Grosmark A, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis MA. Dopaminergic control of sleep-wake states. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10577-89. PMID 17035544 DOI: 10.1523/JNEUROSCI.1767-06.2006  1
2006 Sotnikova TD, Caron MG, Gainetdinov RR. DDD mice, a novel acute mouse model of Parkinson's disease. Neurology. 67: S12-7. PMID 17030735  1
2006 Cho DI, Beom S, Van Tol HH, Caron MG, Kim KM. Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors. Biochemical and Biophysical Research Communications. 350: 634-40. PMID 17022946 DOI: 10.1016/j.bbrc.2006.09.090  0.52
2006 Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice. The Journal of Biological Chemistry. 281: 32072-80. PMID 16954211 DOI: 10.1074/jbc.M606062200  1
2006 Prado VF, Martins-Silva C, de Castro BM, Lima RF, Barros DM, Amaral E, Ramsey AJ, Sotnikova TD, Ramirez MR, Kim HG, Rossato JI, Koenen J, Quan H, Cota VR, Moraes MF, ... ... Caron MG, et al. Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. Neuron. 51: 601-12. PMID 16950158 DOI: 10.1016/j.neuron.2006.08.005  1
2006 Meloni AR, Fralish GB, Kelly P, Salahpour A, Chen JK, Wechsler-Reya RJ, Lefkowitz RJ, Caron MG. Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2. Molecular and Cellular Biology. 26: 7550-60. PMID 16908539 DOI: 10.1128/MCB.00546-06  1
2006 Sotnikova TD, Beaulieu JM, Gainetdinov RR, Caron MG. Molecular biology, pharmacology and functional role of the plasma membrane dopamine transporter. Cns & Neurological Disorders Drug Targets. 5: 45-56. PMID 16613553 DOI: 10.2174/187152706784111579  1
2006 Zhang X, Beaulieu JM, Gainetdinov RR, Caron MG. Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2. Cellular and Molecular Life Sciences : Cmls. 63: 6-11. PMID 16378243 DOI: 10.1007/s00018-005-5417-4  1
2006 Marion S, Oakley RH, Kim KM, Caron MG, Barak LS. A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors. The Journal of Biological Chemistry. 281: 2932-8. PMID 16319069 DOI: 10.1074/jbc.M508074200  0.8
2005 Beaulieu JM, Caron MG. Beta-arrestin goes nuclear. Cell. 123: 755-7. PMID 16325568 DOI: 10.1016/j.cell.2005.11.010  1
2005 Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell. 122: 261-73. PMID 16051150 DOI: 10.1016/j.cell.2005.05.012  1
2005 Sotnikova TD, Beaulieu JM, Barak LS, Wetsel WC, Caron MG, Gainetdinov RR. Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. Plos Biology. 3: e271. PMID 16050778 DOI: 10.1371/journal.pbio.0030271  1
2005 Cyr M, Caron MG, Johnson GA, Laakso A. Magnetic resonance imaging at microscopic resolution reveals subtle morphological changes in a mouse model of dopaminergic hyperfunction. Neuroimage. 26: 83-90. PMID 15862208 DOI: 10.1016/j.neuroimage.2005.01.039  0.72
2005 Pogorelov VM, Rodriguiz RM, Insco ML, Caron MG, Wetsel WC. Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1818-31. PMID 15856082 DOI: 10.1038/sj.npp.1300724  1
2005 Vroon A, Kavelaars A, Limmroth V, Lombardi MS, Goebel MU, Van Dam AM, Caron MG, Schedlowski M, Heijnen CJ. G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 174: 4400-6. PMID 15778405  1
2005 Torres GE, Caron MG. Approaches to identify monoamine transporter interacting proteins. Journal of Neuroscience Methods. 143: 63-8. PMID 15763137 DOI: 10.1016/j.jneumeth.2004.09.012  1
2005 Medvedev IO, Gainetdinov RR, Sotnikova TD, Bohn LM, Caron MG, Dykstra LA. Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice. Psychopharmacology. 180: 408-13. PMID 15719221 DOI: 10.1007/s00213-005-2173-y  1
2005 Kim KM, Gainetdinov RR, Laporte SA, Caron MG, Barak LS. G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation. The Journal of Biological Chemistry. 280: 12774-80. PMID 15687500 DOI: 10.1074/jbc.M408901200  1
2005 Zhang X, Gainetdinov RR, Beaulieu JM, Sotnikova TD, Burch LH, Williams RB, Schwartz DA, Krishnan KR, Caron MG. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron. 45: 11-6. PMID 15629698 DOI: 10.1016/j.neuron.2004.12.014  1
2004 Wilbanks AM, Fralish GB, Kirby ML, Barak LS, Li YX, Caron MG. Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway. Science (New York, N.Y.). 306: 2264-7. PMID 15618520 DOI: 10.1126/science.1104193  1
2004 Robertson GS, Lee CJ, Sridhar K, Nakabeppu Y, Cheng M, Wang YM, Caron MG. Clozapine-, but not haloperidol-, induced increases in deltaFosB-like immunoreactivity are completely blocked in the striatum of mice lacking D3 dopamine receptors. The European Journal of Neuroscience. 20: 3189-94. PMID 15579174 DOI: 10.1111/j.1460-9568.2004.03774.x  1
2004 Torres GE, Sweeney AL, Beaulieu JM, Shashidharan P, Caron MG. Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant. Proceedings of the National Academy of Sciences of the United States of America. 101: 15650-5. PMID 15505207 DOI: 10.1073/pnas.0308088101  1
2004 Mohn AR, Yao WD, Caron MG. Genetic and genomic approaches to reward and addiction. Neuropharmacology. 47: 101-10. PMID 15464129 DOI: 10.1016/j.neuropharm.2004.07.025  0.88
2004 Sotnikova TD, Budygin EA, Jones SR, Dykstra LA, Caron MG, Gainetdinov RR. Dopamine transporter-dependent and -independent actions of trace amine beta-phenylethylamine. Journal of Neurochemistry. 91: 362-73. PMID 15447669 DOI: 10.1111/j.1471-4159.2004.02721.x  1
2004 Vizi ES, Zsilla G, Caron MG, Kiss JP. Uptake and release of norepinephrine by serotonergic terminals in norepinephrine transporter knock-out mice: implications for the action of selective serotonin reuptake inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7888-94. PMID 15356201 DOI: 10.1523/JNEUROSCI.1506-04.2004  1
2004 Keller NR, Diedrich A, Appalsamy M, Tuntrakool S, Lonce S, Finney C, Caron MG, Robertson D. Norepinephrine transporter-deficient mice exhibit excessive tachycardia and elevated blood pressure with wakefulness and activity. Circulation. 110: 1191-6. PMID 15337696 DOI: 10.1161/01.CIR.0000141804.90845.E6  1
2004 Zhang X, Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase-2 controls brain serotonin synthesis. Science (New York, N.Y.). 305: 217. PMID 15247473 DOI: 10.1126/science.1097540  1
2004 Gainetdinov RR, Premont RT, Bohn LM, Lefkowitz RJ, Caron MG. Desensitization of G protein-coupled receptors and neuronal functions. Annual Review of Neuroscience. 27: 107-44. PMID 15217328 DOI: 10.1146/annurev.neuro.27.070203.144206  1
2004 Bohn LM, Dykstra LA, Lefkowitz RJ, Caron MG, Barak LS. Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery. Molecular Pharmacology. 66: 106-12. PMID 15213301 DOI: 10.1124/mol.66.1.106  1
2004 Xu M, Petraschka M, McLaughlin JP, Westenbroek RE, Caron MG, Lefkowitz RJ, Czyzyk TA, Pintar JE, Terman GW, Chavkin C. Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4576-84. PMID 15140929 DOI: 10.1523/JNEUROSCI.5552-03.2004  1
2004 Quan H, Athirakul K, Wetsel WC, Torres GE, Stevens R, Chen YT, Coffman TM, Caron MG. Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2. Molecular and Cellular Biology. 24: 4166-73. PMID 15121838 DOI: 10.1128/MCB.24.10.4166-4173.2004  1
2004 Beom S, Cheong D, Torres G, Caron MG, Kim KM. Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal-regulated kinase Journal of Biological Chemistry. 279: 28304-28314. PMID 15102843 DOI: 10.1074/jbc.M403899200  1
2004 Beaulieu JM, Sotnikova TD, Yao WD, Kockeritz L, Woodgett JR, Gainetdinov RR, Caron MG. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. 101: 5099-104. PMID 15044694 DOI: 10.1073/pnas.0307921101  1
2004 Bohn LM, Gainetdinov RR, Caron MG. G protein-coupled receptor kinase/beta-arrestin systems and drugs of abuse: psychostimulant and opiate studies in knockout mice. Neuromolecular Medicine. 5: 41-50. PMID 15001811 DOI: 10.1385/NMM:5:1:041  1
2004 Yao WD, Gainetdinov RR, Arbuckle MI, Sotnikova TD, Cyr M, Beaulieu JM, Torres GE, Grant SG, Caron MG. Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron. 41: 625-38. PMID 14980210 DOI: 10.1016/S0896-6273(04)00048-0  1
2004 Vroon A, Heijnen CJ, Lombardi MS, Cobelens PM, Mayor F, Caron MG, Kavelaars A. Reduced GRK2 level in T cells potentiates chemotaxis and signaling in response to CCL4 Journal of Leukocyte Biology. 75: 901-909. PMID 14761932 DOI: 10.1189/jlb.0403136  1
2004 Powell SB, Lehmann-Masten VD, Paulus MP, Gainetdinov RR, Caron MG, Geyer MA. MDMA "ecstasy" alters hyperactive and perseverative behaviors in dopamine transporter knockout mice. Psychopharmacology. 173: 310-7. PMID 14747902 DOI: 10.1007/s00213-003-1765-7  1
2004 Rodriguiz RM, Chu R, Caron MG, Wetsel WC. Aberrant responses in social interaction of dopamine transporter knockout mice. Behavioural Brain Research. 148: 185-98. PMID 14684259 DOI: 10.1016/S0166-4328(03)00187-6  1
2004 Terman GW, Jin W, Cheong YP, Lowe J, Caron MG, Lefkowitz RJ, Chavkin C. G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal. British Journal of Pharmacology. 141: 55-64. PMID 14662727 DOI: 10.1038/sj.bjp.0705595  1
2004 Barr AM, Lehmann-Masten V, Paulus M, Gainetdinov RR, Caron MG, Geyer MA. The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 221-8. PMID 14603268 DOI: 10.1038/sj.npp.1300343  1
2004 Marion S, Weiner DM, Caron MG. RNA Editing Induces Variation in Desensitization and Trafficking of 5-Hydroxytryptamine 2c Receptor Isoforms Journal of Biological Chemistry. 279: 2945-2954. PMID 14602721 DOI: 10.1074/jbc.M308742200  1
2004 McLaughlin JP, Myers LC, Zarek PE, Caron MG, Lefkowitz RJ, Czyzyk TA, Pintar JE, Chavkin C. Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance. The Journal of Biological Chemistry. 279: 1810-8. PMID 14597630 DOI: 10.1074/jbc.M305796200  1
2004 Walker JK, Gainetdinov RR, Feldman DS, McFawn PK, Caron MG, Lefkowitz RJ, Premont RT, Fisher JT. G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L312-9. PMID 14565944 DOI: 10.1152/ajplung.00255.2003  1
2004 Ferguson SS, Caron MG. Green fluorescent protein-tagged beta-arrestin translocation as a measure of G protein-coupled receptor activation. Methods in Molecular Biology (Clifton, N.J.). 237: 121-6. PMID 14501044  0.88
2003 Barak LS, Wilbanks AM, Caron MG. Constitutive desensitization: a new paradigm for g protein-coupled receptor regulation. Assay and Drug Development Technologies. 1: 339-46. PMID 15090199 DOI: 10.1089/15406580360545152  1
2003 Bohn LM, Gainetdinov RR, Sotnikova TD, Medvedev IO, Lefkowitz RJ, Dykstra LA, Caron MG. Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10265-73. PMID 14614085  1
2003 Johnson EC, Bohn LM, Barak LS, Birse RT, Nässel DR, Caron MG, Taghert PH. Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions. The Journal of Biological Chemistry. 278: 52172-8. PMID 14555656 DOI: 10.1074/jbc.M306756200  1
2003 Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science (New York, N.Y.). 301: 1391-4. PMID 12958364 DOI: 10.1126/science.1082808  1
2003 Cyr M, Beaulieu JM, Laakso A, Sotnikova TD, Yao WD, Bohn LM, Gainetdinov RR, Caron MG. Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 100: 11035-40. PMID 12958210 DOI: 10.1073/pnas.1831768100  1
2003 Torres GE, Caron MG. Center stage for the serotonin transporter: a gain-of-function polymorphism in persons with obsessive-compulsive disorder. Molecular Pharmacology. 64: 196-8. PMID 12869622 DOI: 10.1124/mol.64.2.196  1
2003 Miyakawa T, Leiter LM, Gerber DJ, Gainetdinov RR, Sotnikova TD, Zeng H, Caron MG, Tonegawa S. Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 100: 8987-92. PMID 12851457 DOI: 10.1073/pnas.1432926100  1
2003 Gainetdinov RR, Bohn LM, Sotnikova TD, Cyr M, Laakso A, Macrae AD, Torres GE, Kim KM, Lefkowitz RJ, Caron MG, Premont RT. Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice. Neuron. 38: 291-303. PMID 12718862 DOI: 10.1016/S0896-6273(03)00192-2  1
2003 Trinh JV, Nehrenberg DL, Jacobsen JP, Caron MG, Wetsel WC. Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice. Neuroscience. 118: 297-310. PMID 12699766 DOI: 10.1016/S0306-4522(03)00165-9  1
2003 Torres GE, Gainetdinov RR, Caron MG. Plasma membrane monoamine transporters: structure, regulation and function. Nature Reviews. Neuroscience. 4: 13-25. PMID 12511858 DOI: 10.1038/nrn1008  1
2003 Tohgo A, Choy EW, Gesty-Palmer D, Pierce KL, Laporte S, Oakley RH, Caron MG, Lefkowitz RJ, Luttrell LM. The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. The Journal of Biological Chemistry. 278: 6258-67. PMID 12473660 DOI: 10.1074/jbc.M212231200  1
2003 Torres GE, Carneiro A, Seamans K, Fiorentini C, Sweeney A, Yao WD, Caron MG. Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter. The Journal of Biological Chemistry. 278: 2731-9. PMID 12429746 DOI: 10.1074/jbc.M201926200  1
2003 Gainetdinov RR, Caron MG. Monoamine transporters: from genes to behavior. Annual Review of Pharmacology and Toxicology. 43: 261-84. PMID 12359863 DOI: 10.1146/annurev.pharmtox.43.050802.112309  1
2003 Caron MG. Transporter mediated regulation of neural communication Journal of Neurochemistry. 85: 2-2. DOI: 10.1046/J.1471-4159.85.S2.2_4.X  0.44
2002 Bohn LM, Lefkowitz RJ, Caron MG. Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10494-500. PMID 12451149  1
2002 Laakso A, Mohn AR, Gainetdinov RR, Caron MG. Experimental genetic approaches to addiction. Neuron. 36: 213-28. PMID 12383778 DOI: 10.1016/S0896-6273(02)00972-8  1
2002 Gainetdinov RR, Sotnikova TD, Caron MG. Monoamine transporter pharmacology and mutant mice. Trends in Pharmacological Sciences. 23: 367-73. PMID 12377578 DOI: 10.1016/S0165-6147(02)02044-8  1
2002 Barbosa J, Ferreira LT, Martins-Silva C, Santos MS, Torres GE, Caron MG, Gomez MV, Ferguson SS, Prado MA, Prado VF. Trafficking of the vesicular acetylcholine transporter in SN56 cells: a dynamin-sensitive step and interaction with the AP-2 adaptor complex. Journal of Neurochemistry. 82: 1221-8. PMID 12358769 DOI: 10.1046/j.1471-4159.2002.01068.x  1
2002 Wilbanks AM, Laporte SA, Bohn LM, Barak LS, Caron MG. Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors. Biochemistry. 41: 11981-9. PMID 12356298 DOI: 10.1021/bi020275m  1
2002 Carneiro AM, Ingram SL, Beaulieu JM, Sweeney A, Amara SG, Thomas SM, Caron MG, Torres GE. The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7045-54. PMID 12177201  1
2002 Savelieva KV, Caudle WM, Findlay GS, Caron MG, Miller GW. Decreased ethanol preference and consumption in dopamine transporter female knock-out mice. Alcoholism, Clinical and Experimental Research. 26: 758-64. PMID 12068242 DOI: 10.1097/00000374-200206000-00003  1
2002 Claing A, Laporte SA, Caron MG, Lefkowitz RJ. Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins. Progress in Neurobiology. 66: 61-79. PMID 11900882 DOI: 10.1016/S0301-0082(01)00023-5  1
2002 Kim YM, Barak LS, Caron MG, Benovic JL. Regulation of arrestin-3 phosphorylation by casein kinase II. The Journal of Biological Chemistry. 277: 16837-46. PMID 11877451 DOI: 10.1074/jbc.M201379200  1
2002 Laporte SA, Miller WE, Kim KM, Caron MG. beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin. The Journal of Biological Chemistry. 277: 9247-54. PMID 11777907 DOI: 10.1074/jbc.M108490200  0.68
2002 Seachrist JL, Laporte SA, Dale LB, Babwah AV, Caron MG, Anborgh PH, Ferguson SS. Rab5 association with the angiotensin II type 1A receptor promotes Rab5 GTP binding and vesicular fusion. The Journal of Biological Chemistry. 277: 679-85. PMID 11682489 DOI: 10.1074/jbc.M109022200  1
2001 Miller GW, Wang YM, Gainetdinov RR, Caron MG. Dopamine transporter and vesicular monoamine transporter knockout mice : implications for Parkinson's disease. Methods in Molecular Medicine. 62: 179-90. PMID 21318776 DOI: 10.1385/1-59259-142-6:179  1
2001 Gerber DJ, Sotnikova TD, Gainetdinov RR, Huang SY, Caron MG, Tonegawa S. Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 15312-7. PMID 11752469 DOI: 10.1073/pnas.261583798  1
2001 Gu HH, Wu X, Giros B, Caron MG, Caplan MJ, Rudnick G. The NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells. Molecular Biology of the Cell. 12: 3797-807. PMID 11739781  1
2001 Mundorf ML, Joseph JD, Austin CM, Caron MG, Wightman RM. Catecholamine release and uptake in the mouse prefrontal cortex. Journal of Neurochemistry. 79: 130-42. PMID 11595765 DOI: 10.1046/j.1471-4159.2001.00554.x  1
2001 Gainetdinov RR, Mohn AR, Bohn LM, Caron MG. Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 98: 11047-54. PMID 11572967 DOI: 10.1073/pnas.191353298  1
2001 Gainetdinov RR, Mohn AR, Caron MG. Genetic animal models: Focus on schizophrenia Trends in Neurosciences. 24: 527-533. PMID 11506886 DOI: 10.1016/S0166-2236(00)01886-5  1
2001 Premont RT, Gainetdinov RR, Caron MG. Following the trace of elusive amines Proceedings of the National Academy of Sciences of the United States of America. 98: 9474-9475. PMID 11504935 DOI: 10.1073/pnas.181356198  1
2001 Kim KM, Valenzano KJ, Robinson SR, Yao WD, Barak LS, Caron MG. Differential regulation of the dopamine D2 and D3 receptors by G protein-coupled receptor kinases and beta-arrestins. The Journal of Biological Chemistry. 276: 37409-14. PMID 11473130 DOI: 10.1074/jbc.M106728200  0.8
2001 Pifl C, Zezula J, Spittler A, Kattinger A, Reither H, Caron MG, Hornykiewicz O. Antiproliferative action of dopamine and norepinephrine in neuroblastoma cells expressing the human dopamine transporter. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1607-9. PMID 11427501 DOI: 10.1096/fj.00-0738fje  1
2001 Torres GE, Yao WD, Mohn AR, Quan H, Kim KM, Levey AI, Staudinger J, Caron MG. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron. 30: 121-34. PMID 11343649 DOI: 10.1016/S0896-6273(01)00267-7  1
2001 Gainetdinov RR, Caron MG, Lombroso PJ. Genetics of childhood disorders: XXIV. ADHD, part 8: Hyperdopaminergic mice as an animal model of ADHD Journal of the American Academy of Child and Adolescent Psychiatry. 40: 380-382. PMID 11288782  1
2001 Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*. The Journal of Biological Chemistry. 276: 19452-60. PMID 11279203 DOI: 10.1074/jbc.M101450200  0.8
2001 Naga Prasad SV, Barak LS, Rapacciuolo A, Caron MG, Rockman HA. Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by β-adrenergic receptor kinase 1: A role in receptor sequestration Journal of Biological Chemistry. 276: 18953-18959. PMID 11259422 DOI: 10.1074/jbc.M102376200  1
2001 Hobson JP, Rosenfeldt HM, Barak LS, Olivera A, Poulton S, Caron MG, Milstien S, Spiegel S. Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility. Science (New York, N.Y.). 291: 1800-3. PMID 11230698 DOI: 10.1126/science.1057559  0.8
2001 Zhuang X, Oosting RS, Jones SR, Gainetdinov RR, Miller GW, Caron MG, Hen R. Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 1982-7. PMID 11172062 DOI: 10.1073/pnas.98.4.1982  1
2001 Ralph RJ, Paulus MP, Fumagalli F, Caron MG, Geyer MA. Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 305-13. PMID 11150348  1
2000 Bohn LM, Gainetdinov RR, Lin FT, Lefkowitz RJ, Caron MG. Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature. 408: 720-3. PMID 11130073 DOI: 10.1038/35047086  1
2000 Bohn LM, Xu F, Gainetdinov RR, Caron MG. Potentiated opioid analgesia in norepinephrine transporter knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9040-5. PMID 11124980  1
2000 Walker JKL, Gainetdinov RR, Mangel AW, Caron MG, Shetzline MA. Mice lacking the dopamine transporter display altered regulation of distal colonic motility American Journal of Physiology - Gastrointestinal and Liver Physiology. 279: G311-G318. PMID 10915639  1
2000 Ciliax BJ, Nash N, Heilman C, Sunahara R, Hartney A, Tiberi M, Rye DB, Caron MG, Niznik HB, Levey AI. Dopamine D(5) receptor immunolocalization in rat and monkey brain. Synapse (New York, N.Y.). 37: 125-45. PMID 10881034 DOI: 10.1002/1098-2396(200008)37:2<125::AID-SYN7>3.0.CO;2-7  1
2000 Spielewoy C, Gonon F, Roubert C, Fauchey V, Jaber M, Caron MG, Roques BP, Hamon M, Betancur C, Maldonado R, Giros B. Increased rewarding properties of morphine in dopamine-transporter knockout mice. The European Journal of Neuroscience. 12: 1827-37. PMID 10792459 DOI: 10.1046/j.1460-9568.2000.00063.x  1
2000 Laporte SA, Oakley RH, Holt JA, Barak LS, Caron MG. The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits. The Journal of Biological Chemistry. 275: 23120-6. PMID 10770944 DOI: 10.1074/jbc.M002581200  0.8
2000 Xu F, Gainetdinov RR, Wetsel WC, Jones SR, Bohn LM, Miller GW, Wang YM, Caron MG. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nature Neuroscience. 3: 465-71. PMID 10769386 DOI: 10.1038/74839  1
2000 Oakley RH, Laporte SA, Holt JA, Caron MG, Barak LS. Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. The Journal of Biological Chemistry. 275: 17201-10. PMID 10748214 DOI: 10.1074/jbc.M910348199  0.8
2000 Carman CV, Barak LS, Chen C, Liu-Chen LY, Onorato JJ, Kennedy SP, Caron MG, Benovic JL. Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 275: 10443-52. PMID 10744734 DOI: 10.1074/jbc.275.14.10443  1
2000 Dumartin B, Jaber M, Gonon F, Caron MG, Giros B, Bloch B. Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 1879-84. PMID 10677550 DOI: 10.1073/pnas.97.4.1879  1
2000 Fauchey V, Jaber M, Caron MG, Bloch B, Le Moine C. Differential regulation of the dopamine D1, D2 and D3 receptor gene expression and changes in the phenotype of the striatal neurons in mice lacking the dopamine transporter. The European Journal of Neuroscience. 12: 19-26. PMID 10651856 DOI: 10.1046/J.1460-9568.2000.00876.X  0.76
2000 Gainetdinov RR, Caron MG. An animal model of attention deficit hyperactivity disorder Molecular Medicine Today. 6: 43-44. PMID 10637574 DOI: 10.1016/S1357-4310(99)01616-0  1
2000 Travis ER, Wang YM, Michael DJ, Caron MG, Wightman RM. Differential quantal release of histamine and 5-hydroxytryptamine from mast cells of vesicular monoamine transporter 2 knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 162-7. PMID 10618388 DOI: 10.1073/pnas.97.1.162  1
2000 Bliziotes M, McLoughlin S, Gunness M, Fumagalli F, Jones SR, Caron MG. Bone histomorphometric and biomechanical abnormalities in mice homozygous for deletion of the dopamine transporter gene. Bone. 26: 15-9. PMID 10617152 DOI: 10.1016/S8756-3282(99)00232-X  1
2000 Caron MG, Mohn AR, Gainetdinov RR. Manifestation of dopamine and glutamate systems dysfunction in animal models of schizoid behavior Acta Neurologica Scandinavica, Supplement. 102: 14-15.  1
1999 Walker JKL, Peppel K, Lefkowitz RJ, Caron MG, Fisher JT. Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 276: R1214-R1221. PMID 29592499 DOI: 10.1152/ajpregu.1999.276.4.R1214  1
1999 Barak LS, Zhang J, Ferguson SS, Laporte SA, Caron MG. Signaling, desensitization, and trafficking of G protein-coupled receptors revealed by green fluorescent protein conjugates. Methods in Enzymology. 302: 153-71. PMID 12876769 DOI: 10.1016/S0076-6879(99)02016-9  0.88
1999 Gainetdinov RR, Bohn LM, Walker JK, Laporte SA, Macrae AD, Caron MG, Lefkowitz RJ, Premont RT. Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice. Neuron. 24: 1029-36. PMID 10624964  1
1999 Bohn LM, Lefkowitz RJ, Gainetdinov RR, Peppel K, Caron MG, Lin FT. Enhanced morphine analgesia in mice lacking beta-arrestin 2. Science (New York, N.Y.). 286: 2495-8. PMID 10617462 DOI: 10.1126/science.286.5449.2495  1
1999 Jones SR, Gainetdinov RR, Caron MG. Application of microdialysis and voltammetry to assess dopamine functions in genetically altered mice: correlation with locomotor activity. Psychopharmacology. 147: 30-2. PMID 10591864 DOI: 10.1007/s002130051137  1
1999 Jones SR, Joseph JD, Barak LS, Caron MG, Wightman RM. Dopamine neuronal transport kinetics and effects of amphetamine. Journal of Neurochemistry. 73: 2406-14. PMID 10582600 DOI: 10.1046/j.1471-4159.1999.0732406.x  1
1999 Jaber M, Dumartin B, Sagné C, Haycock JW, Roubert C, Giros B, Bloch B, Caron MG. Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter. The European Journal of Neuroscience. 11: 3499-511. PMID 10564358  1
1999 Wang YM, Xu F, Gainetdinov RR, Caron MG. Genetic approaches to studying norepinephrine function: Knockout of the mouse norepinephrine transporter gene Biological Psychiatry. 46: 1124-1130. PMID 10560019 DOI: 10.1016/S0006-3223(99)00245-0  1
1999 Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. The Journal of Biological Chemistry. 274: 32248-57. PMID 10542263 DOI: 10.1074/jbc.274.45.32248  0.8
1999 Gainetdinov RR, Caron MG. Delineating muscarinic receptor functions Proceedings of the National Academy of Sciences of the United States of America. 96: 12222-12223. PMID 10535900 DOI: 10.1073/pnas.96.22.12222  1
1999 Walker JK, Premont RT, Barak LS, Caron MG, Shetzline MA. Properties of secretin receptor internalization differ from those of the beta(2)-adrenergic receptor. The Journal of Biological Chemistry. 274: 31515-23. PMID 10531354 DOI: 10.1074/jbc.274.44.31515  0.92
1999 Miller GW, Gainetdinov RR, Levey AI, Caron MG. Dopamine transporters and neuronal injury. Trends in Pharmacological Sciences. 20: 424-9. PMID 10498956 DOI: 10.1016/S0165-6147(99)01379-6  1
1999 Mohn AR, Gainetdinov RR, Caron MG, Koller BH. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia Cell. 98: 427-436. PMID 10481908 DOI: 10.1016/S0092-8674(00)81972-8  1
1999 Gainetdinov RR, Jones SR, Caron MG. Functional hyperdopaminergia in dopamine transporter knock-out mice. Biological Psychiatry. 46: 303-11. PMID 10435196 DOI: 10.1016/S0006-3223(99)00122-5  1
1999 Jones SR, Gainetdinov RR, Hu XT, Cooper DC, Wightman RM, White FJ, Caron MG. Loss of autoreceptor functions in mice lacking the dopamine transporter. Nature Neuroscience. 2: 649-55. PMID 10404198 DOI: 10.1038/10204  1
1999 Gainetdinov RR, Caron MG. Genetic models in pharmacology: Present status and future Pharmacological Research. 39: 403-404. PMID 10373248 DOI: 10.1006/phrs.1999.0498  1
1999 Campbell KM, de Lecea L, Severynse DM, Caron MG, McGrath MJ, Sparber SB, Sun LY, Burton FH. OCD-Like behaviors caused by a neuropotentiating transgene targeted to cortical and limbic D1+ neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5044-53. PMID 10366637  1
1999 Ralph RJ, Varty GB, Kelly MA, Wang YM, Caron MG, Rubinstein M, Grandy DK, Low MJ, Geyer MA. The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4627-33. PMID 10341260  1
1999 Zhang J, Barak LS, Anborgh PH, Laporte SA, Caron MG, Ferguson SS. Cellular trafficking of G protein-coupled receptor/beta-arrestin endocytic complexes. The Journal of Biological Chemistry. 274: 10999-1006. PMID 10196181 DOI: 10.1074/jbc.274.16.10999  0.88
1999 Laporte SA, Oakley RH, Zhang J, Holt JA, Ferguson SS, Caron MG, Barak LS. The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis. Proceedings of the National Academy of Sciences of the United States of America. 96: 3712-7. PMID 10097102 DOI: 10.1073/PNAS.96.7.3712  0.88
1999 Fumagalli F, Gainetdinov RR, Wang YM, Valenzano KJ, Miller GW, Caron MG. Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2424-31. PMID 10087057  1
1999 Zhang J, Ferguson SS, Law PY, Barak LS, Caron MG. Agonist-specific regulation of delta-opioid receptor trafficking by G protein-coupled receptor kinase and beta-arrestin. Journal of Receptor and Signal Transduction Research. 19: 301-13. PMID 10071766 DOI: 10.3109/10799899909036653  0.88
1999 Luttrell LM, Ferguson SS, Daaka Y, Miller WE, Maudsley S, Della Rocca GJ, Lin F, Kawakatsu H, Owada K, Luttrell DK, Caron MG, Lefkowitz RJ. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science (New York, N.Y.). 283: 655-61. PMID 9924018 DOI: 10.1126/science.283.5402.655  1
1999 Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science (New York, N.Y.). 283: 397-401. PMID 9888856 DOI: 10.1126/science.283.5400.397  1
1998 Rocha BA, Fumagalli F, Gainetdinov RR, Jones SR, Ator R, Giros B, Miller GW, Caron MG. Cocaine self-administration in dopamine-transporter knockout mice. Nature Neuroscience. 1: 132-7. PMID 10195128 DOI: 10.1038/381  1
1998 Cases O, Lebrand C, Giros B, Vitalis T, De Maeyer E, Caron MG, Price DJ, Gaspar P, Seif I. Plasma membrane transporters of serotonin, dopamine, and norepinephrine mediate serotonin accumulation in atypical locations in the developing brain of monoamine oxidase A knock-outs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6914-27. PMID 9712661  1
1998 Rockman HA, Choi DJ, Akhter SA, Jaber M, Giros B, Lefkowitz RJ, Caron MG, Koch WJ. Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. The Journal of Biological Chemistry. 273: 18180-4. PMID 9660778 DOI: 10.1074/jbc.273.29.18180  1
1998 Gainetdinov RR, Jones SR, Fumagalli F, Wightman RM, Caron MG. Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis. Brain Research. Brain Research Reviews. 26: 148-53. PMID 9651511 DOI: 10.1016/S0165-0173(97)00063-5  1
1998 Fumagalli F, Gainetdinov RR, Valenzano KJ, Caron MG. Role of dopamine transporter in methamphetamine-induced neurotoxicity: Evidence from mice lacking the transporter Journal of Neuroscience. 18: 4861-4869. PMID 9634552  1
1998 Zhang J, Ferguson SS, Barak LS, Bodduluri SR, Laporte SA, Law PY, Caron MG. Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness. Proceedings of the National Academy of Sciences of the United States of America. 95: 7157-62. PMID 9618555 DOI: 10.1073/PNAS.95.12.7157  0.88
1998 Ferguson SS, Caron MG. G protein-coupled receptor adaptation mechanisms. Seminars in Cell & Developmental Biology. 9: 119-27. PMID 9599406 DOI: 10.1006/scdb.1997.0216  0.88
1998 Ferguson SS, Zhang J, Barak LS, Caron MG. Molecular mechanisms of G protein-coupled receptor desensitization and resensitization. Life Sciences. 62: 1561-5. PMID 9585136 DOI: 10.1016/S0024-3205(98)00107-6  0.88
1998 Pitcher JA, Hall RA, Daaka Y, Zhang J, Ferguson SS, Hester S, Miller S, Caron MG, Lefkowitz RJ, Barak LS. The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin. The Journal of Biological Chemistry. 273: 12316-24. PMID 9575184 DOI: 10.1074/jbc.273.20.12316  1
1998 Gainetdinov RR, Fumagalli F, Wang YM, Jones SR, Levey AI, Miller GW, Caron MG. Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice. Journal of Neurochemistry. 70: 1973-8. PMID 9572281  1
1998 Jones SR, Gainetdinov RR, Jaber M, Giros B, Wightman RM, Caron MG. Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 95: 4029-34. PMID 9520487 DOI: 10.1073/pnas.95.7.4029  1
1998 Shetzline MA, Premont RT, Walker JK, Vigna SR, Caron MG. A role for receptor kinases in the regulation of class II G protein-coupled receptors. Phosphorylation and desensitization of the secretin receptor. The Journal of Biological Chemistry. 273: 6756-62. PMID 9506976 DOI: 10.1074/JBC.273.12.6756  0.92
1998 Jones SR, Gainetdinov RR, Wightman RM, Caron MG. Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1979-86. PMID 9482784  1
1998 Missale C, Nash SR, Robinson SW, Jaber M, Caron MG. Dopamine receptors: from structure to function. Physiological Reviews. 78: 189-225. PMID 9457173 DOI: 10.1152/PHYSREV.1998.78.1.189  0.76
1998 Daaka Y, Luttrell LM, Ahn S, Della Rocca GJ, Ferguson SS, Caron MG, Lefkowitz RJ. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. The Journal of Biological Chemistry. 273: 685-8. PMID 9422717 DOI: 10.1074/jbc.273.2.685  1
1998 Ferguson SS, Zhang J, Barak LS, Caron MG. Role of beta-arrestins in the intracellular trafficking of G-protein-coupled receptors. Advances in Pharmacology (San Diego, Calif.). 42: 420-4. PMID 9327929 DOI: 10.1016/S1054-3589(08)60778-4  0.88
1998 Fumagalli F, Jones S, Bossé R, Jaber M, Giros B, Missale C, Wightman RM, Caron MG. Inactivation of the dopamine transporter reveals essential roles of dopamine in the control of locomotion, psychostimulant response, and pituitary function. Advances in Pharmacology (San Diego, Calif.). 42: 179-82. PMID 9327873 DOI: 10.1016/S1054-3589(08)60722-X  1
1997 Wang YM, Gainetdinov RR, Fumagalli F, Xu F, Jones SR, Bock CB, Miller GW, Wightman RM, Caron MG. Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. Neuron. 19: 1285-96. PMID 9427251 DOI: 10.1016/S0896-6273(00)80419-5  1
1997 Jaber M, Jones S, Giros B, Caron MG. The dopamine transporter: a crucial component regulating dopamine transmission. Movement Disorders : Official Journal of the Movement Disorder Society. 12: 629-33. PMID 9380041 DOI: 10.1002/mds.870120502  1
1997 Barak LS, Ferguson SS, Zhang J, Caron MG. A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation. The Journal of Biological Chemistry. 272: 27497-500. PMID 9346876 DOI: 10.1074/jbc.272.44.27497  0.88
1997 Zhang J, Barak LS, Winkler KE, Caron MG, Ferguson SS. A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types. The Journal of Biological Chemistry. 272: 27005-14. PMID 9341139 DOI: 10.1074/jbc.272.43.27005  1
1997 Peppel K, Boekhoff I, McDonald P, Breer H, Caron MG, Lefkowitz RJ. G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization. The Journal of Biological Chemistry. 272: 25425-8. PMID 9325250 DOI: 10.1074/jbc.272.41.25425  1
1997 Gainetdinov RR, Fumagalli F, Jones SR, Caron MG. Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter. Journal of Neurochemistry. 69: 1322-5. PMID 9282960  1
1997 Bossé R, Fumagalli F, Jaber M, Giros B, Gainetdinov RR, Wetsel WC, Missale C, Caron MG. Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron. 19: 127-38. PMID 9247269 DOI: 10.1016/S0896-6273(00)80353-0  1
1997 Barak LS, Ferguson SS, Zhang J, Martenson C, Meyer T, Caron MG. Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate. Molecular Pharmacology. 51: 177-84. PMID 9203621 DOI: 10.1124/mol.51.2.177  0.88
1997 Bieniasz PD, Fridell RA, Aramori I, Ferguson SS, Caron MG, Cullen BR. HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor. The Embo Journal. 16: 2599-609. PMID 9184207 DOI: 10.1093/emboj/16.10.2599  0.88
1997 Caron MG. Images in neuroscience. Molecular biology, II. A dopamine transporter mouse knockout. The American Journal of Psychiatry. 153: 1515. PMID 8942444 DOI: 10.1176/AJP.153.12.1515  0.36
1997 Barak LS, Caron MG. Modeling of sequestration and down regulation in cells containing beta2-adrenergic receptors. Journal of Receptor and Signal Transduction Research. 15: 677-90. PMID 8903972 DOI: 10.3109/10799899509045248  0.36
1997 Caron MG. ENDOCRINE REVIEWS and the Peer-Review Process Endocrine Reviews. 18: 3-3. DOI: 10.1210/EDRV.18.1.0293  0.36
1996 Jaber M, Robinson SW, Missale C, Caron MG. Dopamine receptors and brain function. Neuropharmacology. 35: 1503-19. PMID 9025098 DOI: 10.1016/S0028-3908(96)00100-1  0.76
1996 Ferguson SS, Barak LS, Zhang J, Caron MG. G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins. Canadian Journal of Physiology and Pharmacology. 74: 1095-110. PMID 9022829 DOI: 10.1139/CJPP-74-10-1095  0.88
1996 Ferguson SS, Zhang J, Barak LS, Caron MG. G-protein-coupled receptor kinases and arrestins: regulators of G-protein-coupled receptor sequestration. Biochemical Society Transactions. 24: 953-9. PMID 8968491 DOI: 10.1042/bst0240953  0.88
1996 Jaber M, Koch WJ, Rockman H, Smith B, Bond RA, Sulik KK, Ross J, Lefkowitz RJ, Caron MG, Giros B. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. Proceedings of the National Academy of Sciences of the United States of America. 93: 12974-9. PMID 8917529 DOI: 10.1073/pnas.93.23.12974  1
1996 Caron MG. Images in neuroscience. A mouse knockout The American Journal of Psychiatry. 153: 1387. PMID 8890669 DOI: 10.1176/AJP.153.11.1387  1
1996 Brana C, Caille I, Pellevoisin C, Charron G, Aubert I, Caron MG, Carles D, Vital C, Bloch B. Ontogeny of the striatal neurons expressing the D1 dopamine receptor in humans. The Journal of Comparative Neurology. 370: 23-34. PMID 8797154 DOI: 10.1002/(SICI)1096-9861(19960617)370:1<23::AID-CNE3>3.0.CO;2-N  1
1996 Fumagalli F, Jones SR, Caron MG, Seidler FJ, Slotkin TA. Expression of mRNA coding for the serotonin transporter in aged vs. young rat brain: differential effects of glucocorticoids. Brain Research. 719: 225-8. PMID 8782886 DOI: 10.1016/0006-8993(96)00119-9  1
1996 Zhang J, Ferguson SS, Barak LS, Ménard L, Caron MG. Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization. The Journal of Biological Chemistry. 271: 18302-5. PMID 8702465 DOI: 10.1074/jbc.271.31.18302  0.88
1996 Ménard L, Ferguson SS, Barak LS, Bertrand L, Premont RT, Colapietro AM, Lefkowitz RJ, Caron MG. Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration. Biochemistry. 35: 4155-60. PMID 8672451 DOI: 10.1021/bi952961+  1
1996 Tiberi M, Nash SR, Bertrand L, Lefkowitz RJ, Caron MG. Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases. The Journal of Biological Chemistry. 271: 3771-8. PMID 8631993 DOI: 10.1074/JBC.271.7.3771  1
1996 Giros B, Jaber M, Jones SR, Wightman RM, Caron MG. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 379: 606-12. PMID 8628395 DOI: 10.1038/379606a0  1
1996 Ferguson SS, Downey WE, Colapietro AM, Barak LS, Ménard L, Caron MG. Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science (New York, N.Y.). 271: 363-6. PMID 8553074 DOI: 10.1126/science.271.5247.363  0.88
1995 Kwatra MM, Schreurs J, Schwinn DA, Innis MA, Caron MG, Lefkowitz RJ. Immunoaffinity purification of epitope-tagged human beta 2-adrenergic receptor to homogeneity. Protein Expression and Purification. 6: 717-21. PMID 8746622 DOI: 10.1006/prep.1995.0001  1
1995 Gregor P, Nash SR, Caron MG, Seldin MF, Warren ST. Assignment of the creatine transporter gene (SLC6A8) to human chromosome Xq28 telomeric to G6PD Genomics. 25: 332-333. PMID 7774949 DOI: 10.1016/0888-7543(95)80155-F  1
1995 Freedman NJ, Liggett SB, Drachman DE, Pei G, Caron MG, Lefkowitz RJ. Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase. The Journal of Biological Chemistry. 270: 17953-61. PMID 7629102 DOI: 10.1074/jbc.270.30.17953  1
1995 Barak LS, Ménard L, Ferguson SS, Colapietro AM, Caron MG. The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor. Biochemistry. 34: 15407-14. PMID 7492540 DOI: 10.1021/BI00047A003  0.88
1995 Kleber HD, Tamminga CA, Schreur, Willner P, Piercey MF, Caron MG, Wise RA. Pharmacotherapy, current and potential, for the treatment of cocaine dependence Clinical Neuropharmacology. 18: S96-S109.  1
1994 el Mestikawy S, Giros B, Pohl M, Hamon M, Kingsmore SF, Seldin MF, Caron MG. Characterization of an atypical member of the Na+/Cl(-)-dependent transporter family: chromosomal localization and distribution in GABAergic and glutamatergic neurons in the rat brain. Journal of Neurochemistry. 62: 445-55. PMID 8294906  1
1994 Pei G, Tiberi M, Caron MG, Lefkowitz RJ. An approach to the study of G-protein-coupled receptor kinases: An in vitro-purified membrane assay reveals differential receptor specificity and regulation by Gβγ subunits Proceedings of the National Academy of Sciences of the United States of America. 91: 3633-3636. PMID 8170959 DOI: 10.1073/PNAS.91.9.3633  1
1994 Scheinin M, Lomasney JW, Hayden-Hixson DM, Schambra UB, Caron MG, Lefkowitz RJ, Fremeau RT. Distribution of alpha 2-adrenergic receptor subtype gene expression in rat brain. Brain Research. Molecular Brain Research. 21: 133-49. PMID 8164514 DOI: 10.1016/0169-328X(94)90386-7  0.36
1994 Kingsmore SF, Giros B, Suh D, Bieniarz M, Caron MG, Seldin MF. Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion. Nature Genetics. 7: 136-41. PMID 7920630 DOI: 10.1038/ng0694-136  1
1994 Snaprud P, Gerwins P, Caron MG, Libert F, Persson H, Fredholm BB, Fuxe K. A2a/D2 receptor interactions are not observed in COS-7 cells transiently transfected with dopamine D2 and adenosine A2a receptor cDNA. Biochemical Pharmacology. 48: 2043-7. PMID 7802693 DOI: 10.1016/0006-2952(94)90503-7  1
1994 Kwatra MM, Lefkowitz RJ, Caron MG. Partially Purified and Reconstituted G-Protein Coupled Receptors as Substrates of Specific Receptor Kinases Methods. 6: 11-17. DOI: 10.1006/METH.1994.1003  0.6
1993 Giros B, Caron MG. Molecular characterization of the dopamine transporter. Trends in Pharmacological Sciences. 14: 43-9. PMID 8480373 DOI: 10.1016/0165-6147(93)90029-J  1
1993 Gingrich JA, Caron MG. Recent advances in the molecular biology of dopamine receptors. Annual Review of Neuroscience. 16: 299-321. PMID 8460895 DOI: 10.1146/annurev.ne.16.030193.001503  1
1993 Pifl C, Giros B, Caron MG. Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4246-53. PMID 8410185  1
1993 Byerley W, Coon H, Hoff M, Holik J, Waldo M, Freedman R, Caron MG, Giros B. Human dopamine transporter gene not linked to schizophrenia in multigenerational pedigrees. Human Heredity. 43: 319-22. PMID 8406521 DOI: 10.1159/000154151  1
1993 Duncan GE, Breese GR, Criswell HE, Johnson KB, Schambra UB, Mueller RA, Caron MG, Fremeau RT. D1 dopamine receptor binding and mRNA levels are not altered after neonatal 6-hydroxydopamine treatment: evidence against dopamine-mediated induction of D1 dopamine receptors during postnatal development. Journal of Neurochemistry. 61: 1255-62. PMID 8376983 DOI: 10.1111/j.1471-4159.1993.tb13616.x  1
1993 Caron MG. Molecular neurobiology. The chimaeras speak again Nature. 366: 409. PMID 8247146 DOI: 10.1038/366409a0  1
1993 Byerley W, Hoff M, Holik J, Caron MG, Giros B. VNTR polymorphism for the human dopamine transporter gene (DAT1). Human Molecular Genetics. 2: 335. PMID 8098980  1
1993 Price DT, Schwinn DA, Lomasney JW, Allen LF, Caron MG, Lefkowitz RJ. Identification, quantification, and localization of mRNA for three distinct alpha 1 adrenergic receptor subtypes in human prostate. The Journal of Urology. 150: 546-51. PMID 7686987 DOI: 10.1016/S0022-5347(17)35544-1  1
1992 Roth NS, Lefkowitz RJ, Caron MG. Structure and function of the adrenergic receptor family. Advances in Experimental Medicine and Biology. 308: 223-38. PMID 1801586 DOI: 10.1007/978-1-4684-6015-5_20  0.72
1992 Allen LF, Lefkowitz RJ, Caron MG, Cotecchia S. G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity. Proceedings of the National Academy of Sciences of the United States of America. 88: 11354-8. PMID 1662393 DOI: 10.1073/PNAS.88.24.11354  0.4
1992 Inglese J, Koch WJ, Caron MG, Lefkowitz RJ. Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases. Nature. 359: 147-50. PMID 1522899 DOI: 10.1038/359147A0  0.36
1992 Luttrell DK, Hausdorff WP, Moyers JE, Gilmer TM, Parsons SJ, Caron MG, Lefkowitz RJ. Overexpression of pp60c-src is associated with altered regulation of adenylyl cyclase Cellular Signalling. 4: 531-541. PMID 1384635 DOI: 10.1016/0898-6568(92)90022-Z  1
1992 Hausdorff WP, Pitcher JA, Luttrell DK, Linder ME, Kurose H, Parsons SJ, Caron MG, Lefkowitz RJ. Tyrosine phosphorylation of G protein α subunits by pp60c-src Proceedings of the National Academy of Sciences of the United States of America. 89: 5720-5724. PMID 1378615 DOI: 10.1073/pnas.89.13.5720  1
1992 Gingrich JA, Dearry A, Falardeau P, Bates MD, Fremeau RT, Caron MG. Location and molecular cloning of D1 dopamine receptor. Neurochemistry International. 20: 9S-15S. PMID 1365464 DOI: 10.1016/0197-0186(92)90204-5  1
1992 Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ. Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms. Biochemistry. 31: 3193-7. PMID 1348186 DOI: 10.1021/BI00127A021  1
1992 Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. Science (New York, N.Y.). 257: 1264-7. PMID 1325672 DOI: 10.1126/science.1325672  0.48
1992 Ostrowski J, Kjelsberg MA, Caron MG, Lefkowitz RJ. Mutagenesis of the beta 2-adrenergic receptor: how structure elucidates function. Annual Review of Pharmacology and Toxicology. 32: 167-83. PMID 1318669 DOI: 10.1146/ANNUREV.PA.32.040192.001123  0.64
1992 Collins S, Caron MG, Lefkowitz RJ. From ligand binding to gene expression: new insights into the regulation of G-protein-coupled receptors. Trends in Biochemical Sciences. 17: 37-9. PMID 1316650 DOI: 10.1016/0968-0004(92)90425-9  0.36
1992 Giros B, El Mestikawy S, Godinot N, Yang-Feng T, Caron MG. Molecular cloning, pharmacological characterization and genetic studies of the human dopamine transporter European Neuropsychopharmacology. 2: 268-269. DOI: 10.1016/0924-977X(92)90103-F  1
1991 Bates MD, Caron MG, Raymond JR. Desensitization of DA1 dopamine receptors coupled to adenylyl cyclase in opossum kidney cells American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 260. PMID 2058712 DOI: 10.1152/AJPRENAL.1991.260.6.F937  1
1991 Collins S, Caron MG, Lefkowitz RJ. Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression. Annual Review of Physiology. 53: 497-508. PMID 2042970 DOI: 10.1146/ANNUREV.PH.53.030191.002433  0.6
1991 Benovic JL, Stone WC, Huebner K, Croce C, Caron MG, Lefkowitz RJ. cDNA cloning and chromosomal localization of the human α-adrenergic receptor kinase Febs Letters. 283: 122-126. PMID 2037065 DOI: 10.1016/0014-5793(91)80568-N  1
1991 Fremeau RT, Duncan GE, Fornaretto MG, Dearry A, Gingrich JA, Breese GR, Caron MG. Localization of D1 dopamine receptor mRNA in brain supports a role in cognitive, affective, and neuroendocrine aspects of dopaminergic neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 88: 3772-6. PMID 2023928 DOI: 10.1073/PNAS.88.9.3772  1
1991 Blakely RD, Berson HE, Fremeau RT, Caron MG, Peek MM, Prince HK, Bradley CC. Cloning and expression of a functional serotonin transporter from rat brain. Nature. 354: 66-70. PMID 1944572 DOI: 10.1038/354066a0  1
1991 Kurose H, Regan JW, Caron MG, Lefkowitz RJ. Functional interactions of recombinant alpha 2 adrenergic receptor subtypes and G proteins in reconstituted phospholipid vesicles. Biochemistry. 30: 3335-41. PMID 1849000 DOI: 10.1021/bi00227a024  0.32
1991 Gingrich JA, Dearry A, Falardeau P, Fremeau RT, Bates MD, Caron MG. Molecular characterization of G-protein coupled receptors: isolation and cloning of a D1 dopamine receptor. Journal of Receptor Research. 11: 521-34. PMID 1832189 DOI: 10.3109/10799899109066425  1
1991 Tiberi M, Jarvie KR, Silvia C, Falardeau P, Gingrich JA, Godinot N, Bertrand L, Yang-Feng TL, Fremeau RT, Caron MG. Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor. Proceedings of the National Academy of Sciences of the United States of America. 88: 7491-5. PMID 1831904 DOI: 10.1073/PNAS.88.17.7491  1
1991 Fargin A, Yamamoto K, Cotecchia S, Goldsmith PK, Spiegel AM, Lapetina EG, Caron MG, Lefkowitz RJ. Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein. Cellular Signalling. 3: 547-57. PMID 1786205 DOI: 10.1016/0898-6568(91)90031-O  1
1991 Giros B, el Mestikawy S, Bertrand L, Caron MG. Cloning and functional characterization of a cocaine-sensitive dopamine transporter. Febs Letters. 295: 149-54. PMID 1765147 DOI: 10.1016/0014-5793(91)81406-X  1
1991 Oakey RJ, Caron MG, Lefkowitz RJ, Seldin MF. Genomic organization of adrenergic and serotonin receptors in the mouse: linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution. Genomics. 10: 338-44. PMID 1676978 DOI: 10.1016/0888-7543(91)90317-8  0.4
1991 Collins S, Lohse MJ, O'Dowd B, Caron MG, Lefkowitz RJ. Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model. Vitamins and Hormones. 46: 1-39. PMID 1660639 DOI: 10.1016/S0083-6729(08)60681-0  1
1991 Lomasney JW, Cotecchia S, Lefkowitz RJ, Caron MG. Molecular biology of alpha-adrenergic receptors: implications for receptor classification and for structure-function relationships. Biochimica Et Biophysica Acta. 1095: 127-39. PMID 1657194 DOI: 10.1016/0167-4889(91)90075-9  0.44
1991 Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ. Model systems for the study of seven-transmembrane-segment receptors. Annual Review of Biochemistry. 60: 653-88. PMID 1652922 DOI: 10.1146/annurev.bi.60.070191.003253  0.96
1991 Yang SD, Benovic JL, Fong YL, Caron MG, Lefkowitz RJ. Cyclic phosphorylation-dephosphorylation of rhodopsin in retina by protein kinase FA (the activator of ATP.Mg-dependent protein phosphatase) Biochemical and Biophysical Research Communications. 178: 1306-1311. PMID 1651717 DOI: 10.1016/0006-291X(91)91036-C  1
1991 Roth NS, Campbell PT, Caron MG, Lefkowitz RJ, Lohse MJ. Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 88: 6201-4. PMID 1648731 DOI: 10.1073/PNAS.88.14.6201  1
1991 Onorato JJ, Palczewski K, Regan JW, Caron MG, Lefkowitz RJ, Benovic JL. Role of acidic amino acids in peptide substrates of the β-adrenergic receptor kinase and rhodopsin kinase Biochemistry®. 30: 5118-5125. PMID 1645191  1
1990 Andersen PH, Gingrich JA, Bates MD, Dearry A, Falardeau P, Senogles SE, Caron MG. Dopamine receptor subtypes: beyond the D1/D2 classification. Trends in Pharmacological Sciences. 11: 231-6. PMID 2200181 DOI: 10.1016/0165-6147(90)90249-8  1
1990 Lefkowitz RJ, Hausdorff WP, Caron MG. Role of phosphorylation in desensitization of the beta-adrenoceptor. Trends in Pharmacological Sciences. 11: 190-4. PMID 2188401 DOI: 10.1016/0165-6147(90)90113-M  0.52
1990 Collins S, Bouvier M, Lohse MJ, Benovic JL, Caron MG, Lefkowitz RJ. Mechanisms involved in adrenergic receptor desensitization. Biochemical Society Transactions. 18: 541-4. PMID 2177406  1
1990 Benovic JL, Onorato J, Lohse MJ, Dohlman HG, Staniszewski C, Caron MG, Lefkowitz RJ. Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase. British Journal of Clinical Pharmacology. 30: 3S-12S. PMID 2176526 DOI: 10.1111/j.1365-2125.1990.tb05462.x  1
1990 King K, Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ. Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit. Science (New York, N.Y.). 250: 121-3. PMID 2171146  1
1990 Lomasney JW, Lorenz W, Allen LF, Klng K, Regan JW, Yang-Fengh TL, Caron MG, Lefkowitz RJ. Expansion of the α2-adrenergic receptor family: Cloning and characterization of a human α2-adrenergic receptor subtype, the gene for which is located on chromosome 2 Proceedings of the National Academy of Sciences of the United States of America. 87: 5094-5098. PMID 2164221  1
1990 Valiquette M, Bonin H, Hnatowich M, Caron MG, Lefkowitz RJ, Bouvier M. Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor. Proceedings of the National Academy of Sciences of the United States of America. 87: 5089-93. PMID 2164220 DOI: 10.1073/PNAS.87.13.5089  1
1990 Lohse MJ, Benovic JL, Codina J, Caron MG, Lefkowitz RJ. beta-Arrestin: a protein that regulates beta-adrenergic receptor function. Science (New York, N.Y.). 248: 1547-50. PMID 2163110  1
1990 Dohlman HG, Caron MG, DeBlasi A, Frielle T, Lefkowitz RJ. Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptor. Biochemistry. 29: 2335-42. PMID 2159799  1
1990 Cotecchia S, Exum S, Caron MG, Lefkowitz RJ. Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function. Proceedings of the National Academy of Sciences of the United States of America. 87: 2896-900. PMID 2158097 DOI: 10.1073/PNAS.87.8.2896  0.64
1990 Yang-Feng TL, Xue F, Zhong W, Cotecchia S, Frielle T, Caron MG, Lefkowitz RJ, Francke U. Chromosomal organization of adrenergic receptor genes Proceedings of the National Academy of Sciences of the United States of America. 87: 1516-1520. PMID 2154750 DOI: 10.1073/PNAS.87.4.1516  1
1990 Dearry A, Gingrich JA, Falardeau P, Fremeau RT, Bates MD, Caron MG. Molecular cloning and expression of the gene for a human D1 dopamine receptor. Nature. 347: 72-6. PMID 2144334 DOI: 10.1038/347072a0  1
1990 Bates MD, Gingrich JA, Bunzow JR, Falardeau P, Dearry A, Senogles SE, Civelli O, Caron MG. Molecular characterization of dopamine receptors. American Journal of Hypertension. 3: 29S-33S. PMID 2143386  1
1990 Raymond JR, Hnatowich M, Lefkowitz RJ, Caron MG. Adrenergic receptors. Models for regulation of signal transduction processes. Hypertension (Dallas, Tex. : 1979). 15: 119-31. PMID 2105909 DOI: 10.1161/01.HYP.15.2.119  0.64
1990 Seuwen K, Magnaldo I, Kobilka BK, Caron MG, Regan JW, Lefkowitz RJ, Pouysségur J. Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene. Cell Regulation. 1: 445-51. PMID 1981685  1
1990 Hausdorff WP, Caron MG, Lefkowitz RJ. Turning off the signal: desensitization of β‐adrenergic receptor function The Faseb Journal. 4: 2881-2889. DOI: 10.1096/fasebj.4.11.2165947  0.36
1989 Frielle T, Daniel KW, Caron MG, Lefkowitz RJ. Structural basis of beta-adrenergic receptor subtype specificity studied with chimeric beta 1/beta 2-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 85: 9494-8. PMID 2849109 DOI: 10.1073/PNAS.85.24.9494  0.64
1989 Kwatra MM, Benovic JL, Caron MG, Lefkowitz RJ, Hosey MM. Phosphorylation of chick heart muscarinic cholinergic receptors by the β-adrenergic receptor kinase Biochemistry. 28: 4543-4547. PMID 2765501  1
1989 O'Dowd BF, Lefkowitz RJ, Caron MG. Structure of the adrenergic and related receptors. Annual Review of Neuroscience. 12: 67-83. PMID 2648960 DOI: 10.1146/ANNUREV.NE.12.030189.000435  0.76
1989 Caron MG. The guanine nucleotide regulatory protein-coupled receptors for nucleosides, nucleotides, amino acids and amine neurotransmitters Current Opinion in Cell Biology. 1: 159-166. PMID 2561066 DOI: 10.1016/0955-0674(89)90081-1  1
1989 Liggett SB, Bouvier M, O'Dowd BF, Caron MG, Lefkowitz RJ, DeBlasi A. Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization. Biochemical and Biophysical Research Communications. 165: 257-63. PMID 2556136 DOI: 10.1016/0006-291X(89)91063-2  1
1989 Benovic JL, DeBlasi A, Stone WC, Caron MG, Lefkowitz RJ. Β-adrenergic receptor kinase: Primary structure delineates a multigene family Science. 246: 235-240. PMID 2552582  1
1989 Lefkowitz RJ, Kobilka BK, Caron MG. The new biology of drug receptors. Biochemical Pharmacology. 38: 2941-8. PMID 2551299 DOI: 10.1016/0006-2952(89)90001-4  1
1989 Matsui H, Lefkowitz RJ, Caron MG, Regan JW. Localization of the fourth membrane spanning domain as a ligand binding site in the human platelet α2-adrenergic receptor Biochemistry. 28: 4125-4130. PMID 2546589  1
1989 Palacios JM, O'Dowd BF, Cotecchia S, Hnatowich M, Caron MG, Lefkowitz RJ. Adrenergic receptor homologies in vertebrate and invertebrate species examined by DNA hybridization. Life Sciences. 44: 2057-65. PMID 2545987 DOI: 10.1016/0024-3205(89)90352-4  1
1989 Lohse MJ, Lefkowitz RJ, Caron MG, Benovic JL. Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 86: 3011-5. PMID 2541428  1
1989 Collins S, Bolanowski MA, Caron MG, Lefkowitz RJ. Genetic regulation of beta-adrenergic receptors. Annual Review of Physiology. 51: 203-15. PMID 2540696 DOI: 10.1146/ANNUREV.PH.51.030189.001223  0.68
1989 Collins S, Bouvier M, Bolanowski MA, Caron MG, Lefkowitz RJ. cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure. Proceedings of the National Academy of Sciences of the United States of America. 86: 4853-7. PMID 2472635 DOI: 10.1073/PNAS.86.13.4853  1
1989 Frielle T, Kobilka B, Lefkowitz RJ, Caron MG. Human beta 1- and beta 2-adrenergic receptors: structurally and functionally related receptors derived from distinct genes. Trends in Neurosciences. 11: 321-4. PMID 2465637 DOI: 10.1016/0166-2236(88)90095-1  0.48
1989 Frielle T, Caron MG, Lefkowitz RJ. Properties of the beta 1- and beta 2-adrenergic receptor subtypes revealed by molecular cloning. Clinical Chemistry. 35: 721-725. DOI: 10.1093/CLINCHEM/35.5.721  0.64
1988 Gingrich JA, Amlaiky N, Senogles SE, Chang WK, McQuade RD, Berger JG, Caron MG. Affinity chromatography of the D1 dopamine receptor from rat corpus striatum. Biochemistry. 27: 3907-12. PMID 3415962  1
1988 Fargin A, Raymond JR, Lohse MJ, Kobilka BK, Caron MG, Lefkowitz RJ. The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor. Nature. 335: 358-60. PMID 3138543 DOI: 10.1038/335358a0  1
1988 Senogles SE, Amlaiky N, Berger JG, Caron MG. Biochemical properties of D1 and D2 dopamine receptors. Advances in Experimental Medicine and Biology. 235: 33-41. PMID 2976252  1
1988 Lefkowitz RJ, Kobilka BK, Benovic JL, Bouvier M, Cotecchia S, Hausdorff WP, Dohlman HG, Regan JW, Caron MG. Molecular biology of adrenergic receptors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 507-14. PMID 2855490  1
1988 Benovic JL, Bouvier M, Caron MG, Lefkowitz RJ. Regulation of adenylyl cyclase-coupled beta-adrenergic receptors. Annual Review of Cell Biology. 4: 405-28. PMID 2848553 DOI: 10.1146/annurev.cb.04.110188.002201  1
1988 Cotecchia S, Schwinn DA, Randall RR, Lefkowitz RJ, Caron MG, Kobilka BK. Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 7159-63. PMID 2845398 DOI: 10.1073/PNAS.85.19.7159  1
1988 Strasser RH, Benovic JL, Lefkowitz RJ, Caron MG. The beta-adrenergic receptor kinase: role in homologous desensitization in S49 lymphoma cells Advances in Experimental Medicine and Biology. 231: 503-517. PMID 2843012  1
1988 Regan JW, Kobilka TS, Yang-Feng TL, Caron MG, Lefkowitz RJ, Kobilka BK. Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. Proceedings of the National Academy of Sciences of the United States of America. 85: 6301-5. PMID 2842764  1
1988 Caron MG, Kobilka BK, Frielle T, Bolanowski MA, Benovic JL, Lefkowitz RJ. Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors. Journal of Receptor Research. 8: 7-21. PMID 2838630 DOI: 10.3109/10799898809048975  1
1988 Dohlman HG, Caron MG, Strader CD, Amlaiky N, Lefkowitz RJ. Identification and sequence of a binding site peptide of the beta 2-adrenergic receptor. Biochemistry. 27: 1813-7. PMID 2837273  1
1988 Kobilka BK, Kobilka TS, Daniel K, Regan JW, Caron MG, Lefkowitz RJ. Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity. Science (New York, N.Y.). 240: 1310-6. PMID 2836950  1
1988 Bouvier M, Hausdorff WP, De Blasi A, O'Dowd BF, Kobilka BK, Caron MG, Lefkowitz RJ. Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization. Nature. 333: 370-3. PMID 2836733 DOI: 10.1038/333370a0  1
1988 Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways. Endocrine Reviews. 9: 38-56. PMID 2836188 DOI: 10.1210/edrv-9-1-38  1
1987 Kobilka BK, Frielle T, Collins S, Yang-Feng T, Kobilka TS, Francke U, Lefkowitz RJ, Caron MG. An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins. Nature. 329: 75-9. PMID 3041227 DOI: 10.1038/329075a0  0.36
1987 Dohlman HG, Caron MG, Lefkowitz RJ. A family of receptors coupled to guanine nucleotide regulatory proteins. Biochemistry. 26: 2657-64. PMID 3038163  1
1987 Yoshimasa T, Sibley DR, Bouvier M, Lefkowitz RJ, Caron MG. Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation. Nature. 327: 67-70. PMID 3033513 DOI: 10.1038/327067a0  1
1987 Cerione RA, Gierschik P, Staniszewski C, Benovic JL, Codina J, Somers R, Birnbaumer L, Spiegel AM, Lefkowitz RJ, Caron MG. Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein. Biochemistry. 26: 1485-91. PMID 3032251 DOI: 10.1021/bi00379a041  1
1987 Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Regulation of transmembrane signaling by receptor phosphorylation. Cell. 48: 913-22. PMID 3030559 DOI: 10.1016/0092-8674(87)90700-8  1
1987 Kobilka BK, Dixon RA, Frielle T, Dohlman HG, Bolanowski MA, Sigal IS, Yang-Feng TL, Francke U, Caron MG, Lefkowitz RJ. cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. Proceedings of the National Academy of Sciences of the United States of America. 84: 46-50. PMID 3025863 DOI: 10.1073/pnas.84.1.46  1
1987 Lefkowitz RJ, Caron MG. Regulation of adrenergic receptor function by phosphorylation. Current Topics in Cellular Regulation. 28: 209-31. PMID 3024910 DOI: 10.1016/B978-0-12-152828-7.50007-X  0.64
1987 Benovic JL, Staniszewski C, Cerione RA, Codina J, Lefkowitz RJ, Caron MG. The mammalian βadrenergic receptor: Structural and functional characterization of the carbohydrate moiety Journal of Receptors and Signal Transduction. 7: 257-281. PMID 2887651 DOI: 10.3109/10799898709054989  1
1987 Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Molecular mechanisms of beta-adrenergic receptor desensitization. Advances in Experimental Medicine and Biology. 221: 253-73. PMID 2829583 DOI: 10.1007/978-1-4684-7618-7_19  1
1987 Benovic JL, Kühn H, Weyand I, Codina J, Caron MG, Lefkowitz RJ. Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein) Proceedings of the National Academy of Sciences of the United States of America. 84: 8879-8882. PMID 2827157  1
1987 Frielle T, Collins S, Daniel KW, Caron MG, Lefkowitz RJ, Kobilka BK. Cloning of the cDNA for the human beta 1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 84: 7920-4. PMID 2825170 DOI: 10.1073/PNAS.84.22.7920  1
1987 Kobilka BK, Matsui H, Kobilka TS, Yang-Feng TL, Francke U, Caron MG, Lefkowitz RJ, Regan JW. Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. Science (New York, N.Y.). 238: 650-6. PMID 2823383  1
1987 Lefkowitz RJ, Caron MG. Molecular and regulatory properties of adrenergic receptors. Recent Progress in Hormone Research. 43: 469-97. PMID 2819998 DOI: 10.1016/B978-0-12-571143-2.50018-6  0.6
1986 Lefkowitz RJ, Caron MG. Ciba-Geigy award for outstanding research. Regulation of adrenergic receptor function by phosphorylation. Journal of Molecular and Cellular Cardiology. 18: 885-95. PMID 3023644 DOI: 10.1016/S0022-2828(86)80003-7  0.84
1986 Strasser RH, Benovic JL, Caron MG, Lefkowitz RJ. β-Agonist- and prostaglandin E1-induced translocation of the β-adrenergic receptor kinase: Evidence that the kinase may act on multiple adenylate cyclase-coupled receptors Proceedings of the National Academy of Sciences of the United States of America. 83: 6362-6366. PMID 3018728  1
1986 Benovic JL, Mayor F, Somers RL, Caron MG, Lefkowitz RJ. Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase Nature. 321: 869-872. PMID 3014340 DOI: 10.1038/321869a0  1
1986 Dixon RA, Kobilka BK, Strader DJ, Benovic JL, Dohlman HG, Frielle T, Bolanowski MA, Bennett CD, Rands E, Diehl RE, Mumford RA, Slater EE, Sigal IS, Caron MG, Lefkowitz RJ, et al. Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. Nature. 321: 75-9. PMID 3010132 DOI: 10.1038/321075a0  1
1986 Dickinson KE, Leeb-Lundberg LM, Strasser RH, Caron MG, Lefkowitz RJ. Identification of the subunit structure of rat pineal adrenergic receptors by photoaffinity labeling. Journal of Neurochemistry. 46: 1153-60. PMID 3005506 DOI: 10.1111/j.1471-4159.1986.tb00630.x  0.36
1986 Cotecchia S, Leeb-Lundberg LM, Hagen PO, Lefkowitz RJ, Caron MG. Phorbol ester effects on alpha 1-adrenoceptor binding and phosphatidylinositol metabolism in cultured vascular smooth muscle cells. Life Sciences. 37: 2389-98. PMID 3001461 DOI: 10.1016/0024-3205(85)90106-7  0.4
1986 Senogles SE, Amlaiky N, Johnson AL, Caron MG. Affinity chromatography of the anterior pituitary D2-dopamine receptor Biochemistry. 25: 749-753. PMID 2938619  1
1986 Benovic JL, Strasser RH, Caron MG, Lefkowitz RJ. β-Adrenergic receptor kinase: Identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor Proceedings of the National Academy of Sciences of the United States of America. 83: 2797-2801. PMID 2871555  1
1986 Lefkowitz RJ, Benovic JL, Kobilka B, Caron MG. β-Adrenergic receptors and rhodopsin: shedding new light on an old subject Trends in Pharmacological Sciences. 7: 444-448. DOI: 10.1016/0165-6147(86)90417-7  1
1985 Cerione RA, Codina J, Kilpatrick BF, Staniszewski C, Gierschik P, Somers RL, Spiegel AM, Birnbaumer L, Caron MG, Lefkowitz RJ. Transducin and the inhibitory nucleotide regulatory protein inhibit the stimulatory nucleotide regulatory protein mediated stimulation of adenylate cyclase in phospholipid vesicle systems. Biochemistry. 24: 4499-503. PMID 3933556 DOI: 10.1021/bi00338a002  1
1985 Cerione RA, Staniszewski C, Caron MG, Lefkowitz RJ, Codina J, Birnbaumer L. A role for Ni in the hormonal stimulation of adenylate cyclase. Nature. 318: 293-5. PMID 2999605 DOI: 10.1038/318293a0  0.64
1985 Birnbaumer L, Codina J, Mattera R, Cerione RA, Hildebrandt JD, Sunyer T, Rojas FJ, Caron MG, Lefkowitz RJ, Iyengar R. Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins. Recent Progress in Hormone Research. 41: 41-99. PMID 2996090 DOI: 10.1016/B978-0-12-571141-8.50006-8  1
1985 Leeb-Lundberg LM, Cotecchia S, Lomasney JW, DeBernardis JF, Lefkowitz RJ, Caron MG. Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism. Proceedings of the National Academy of Sciences of the United States of America. 82: 5651-5. PMID 2994039 DOI: 10.1073/PNAS.82.17.5651  0.52
1985 Lefkowitz RJ, Cerione RA, Codina J, Birnbaumer L, Caron MG. Reconstitution of the beta-adrenergic receptor. The Journal of Membrane Biology. 87: 1-12. PMID 2865370 DOI: 10.1007/BF01870694  0.52
1984 Amlaiky N, Kilpatrick BF, Caron MG. A novel radioiodinated high affinity ligand for the D2-dopamine receptor. Characterization of its binding in bovine anterior pituitary membranes. Febs Letters. 176: 436-40. PMID 6548453 DOI: 10.1016/0014-5793(84)81213-2  0.32
1984 Kilpatrick BF, Caron MG. Dopamine receptor of the porcine anterior pituitary gland. Solubilization and characterization. Biochemical Pharmacology. 33: 1981-8. PMID 6547344 DOI: 10.1016/0006-2952(84)90559-8  0.32
1984 McDonald WM, Sibley DR, Kilpatrick BF, Caron MG. Dopaminergic inhibition of adenylate cyclase correlates with high affinity agonist binding to anterior pituitary D2 dopamine receptors. Molecular and Cellular Endocrinology. 36: 201-9. PMID 6540722 DOI: 10.1016/0303-7207(84)90037-6  1
1984 DeMarinis RM, Krog AJ, Shah DH, Lafferty J, Holden KG, Hieble JP, Matthews WD, Regan JW, Lefkowitz RJ, Caron MG. Development of an affinity ligand for purification of α2-adrenoceptors from human platelet membranes Journal of Medicinal Chemistry. 27: 918-921. PMID 6330361  1
1984 Heinsimer JA, Davies AO, Downs RW, Levine MA, Spiegel AM, Drezner MK, De Lean A, Wreggett KA, Caron MG, Lefkowitz RJ. Impaired formation of beta-adrenergic receptor-nucleotide regulatory protein complexes in pseudohypoparathyroidism. The Journal of Clinical Investigation. 73: 1335-43. PMID 6325502 DOI: 10.1172/JCI111336  1
1984 Sibley DR, Peters JR, Nambi P, Caron MG, Lefkowitz RJ. Photoaffinity labeling of turkey erythrocyte beta-adrenergic receptors: degradation of the Mr = 49,000 protein explains apparent heterogeneity. Biochemical and Biophysical Research Communications. 119: 458-64. PMID 6324763 DOI: 10.1016/S0006-291X(84)80271-5  1
1984 Williams RS, Caron MG, Daniel K. Skeletal muscle beta-adrenergic receptors: variations due to fiber type and training The American Journal of Physiology. 246. PMID 6320672 DOI: 10.1152/AJPENDO.1984.246.2.E160  1
1984 Cerione RA, Codina J, Benovic JL, Lefkowitz RJ, Birnbaumer L, Caron MG. The mammalian β2-adrenergic receptor: Reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system Biochemistry. 23: 4519-4525. PMID 6149763 DOI: 10.1021/bi00315a003  1
1984 Lefkowitz RJ, Caron MG, Stiles GL. Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors. The New England Journal of Medicine. 310: 1570-9. PMID 6145093 DOI: 10.1056/NEJM198406143102406  0.72
1984 Stiles GL, Caron MG, Lefkowitz RJ. Beta-adrenergic receptors: biochemical mechanisms of physiological regulation. Physiological Reviews. 64: 661-743. PMID 6143332 DOI: 10.1152/physrev.1984.64.2.661  0.72
1984 Nambi P, Sibley DR, Caron MG, Lefkowitz RJ. Photoaffinity labeling of beta-adrenergic receptors in mammalian tissues. Biochemical Pharmacology. 33: 3813-22. PMID 6095862 DOI: 10.1016/0006-2952(84)90045-5  1
1984 Caron MG, Leeb-Lundberg LM, Strader CD, Dickinson KE, Pickel VM, Joh T, Lefkowitz RJ. Molecular biology of adrenergic receptors in the rat and frog central nervous system. Hypertension. 6: II22-7. PMID 6094345 DOI: 10.1161/01.HYP.6.5_PT_2.II22  1
1984 Benovic JL, Shorr RGL, Caron MG, Lefkowitz RJ. The mammalian β2-adrenergic receptor: Purification and characterization Biochemistry. 23: 4510-4518. PMID 6093858 DOI: 10.1021/bi00315a002  1
1984 Strulovici B, Cerione RA, Kilpatrick BF, Caron MG, Lefkowitz RJ. Direct demonstration of impaired functionality of a purified desensitized beta-adrenergic receptor in a reconstituted system. Science (New York, N.Y.). 225: 837-40. PMID 6089331 DOI: 10.1126/science.6089331  0.6
1984 HEALD SL, JEFFS PW, LAVIN TN, NAMBI P, LEFKOWITZ RJ, CARON MG. ChemInform Abstract: Synthesis of Iodine-125 Labeled (±)-15-(4-Azidobenzyl)carazolol: A Potent β-Adrenergic Photoaffinity Probe. Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198408322  0.32
1983 Caron MG, Kilpatrick BF, Sibley DR. Direct radioligand measurement of dopamine receptors in the anterior pituitary gland. Methods in Enzymology. 103: 557-90. PMID 6669043 DOI: 10.1016/S0076-6879(83)03041-4  1
1983 Cerione RA, Strulovici B, Benovic JL, Lefkowitz RJ, Caron MG. Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase Nature. 306: 562-566. PMID 6316161 DOI: 10.1038/306562a0  1
1983 Leeb-Lundberg LM, Dickinson KE, Heald SL, Wikberg JE, DeBernardis JF, Winn M, Arendsen DL, Lefkowitz RJ, Caron MG. Covalent labeling of the cerebral cortex alpha 1-adrenergic receptor with a new high affinity radioiodinated photoaffinity probe. Biochemical and Biophysical Research Communications. 115: 946-51. PMID 6313003 DOI: 10.1016/S0006-291X(83)80026-6  1
1983 Cerione RA, Strulovici B, Benovic JL, Strader CD, Caron MG, Lefkowitz RJ. Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system. Proceedings of the National Academy of Sciences of the United States of America. 80: 4899-903. PMID 6308659 DOI: 10.1073/pnas.80.16.4899  0.52
1983 Stadel JM, Nambi P, Shorr RG, Sawyer DF, Caron MG, Lefkowitz RJ. Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 80: 3173-7. PMID 6304694 DOI: 10.1073/PNAS.80.11.3173  0.56
1983 Heald SL, Jeffs PW, Lavin TN, Nambi P, Lefkowitz RJ, Caron MG. Synthesis of iodine-125 labeled (+/-)-15-(4-azidobenzyl)carazolol: a potent beta-adrenergic photoaffinity probe. Journal of Medicinal Chemistry. 26: 832-8. PMID 6304313  1
1983 Benovic JL, Stiles GL, Lefkowitz RJ, Caron MG. Photoaffinity labelling of mammalian beta-adrenergic receptors: Metal-dependent proteolysis explains apparent heterogeneity Biochemical and Biophysical Research Communications. 110: 504-511. PMID 6301455 DOI: 10.1016/0006-291X(83)91178-6  1
1983 Strader CD, Pickel VM, Joh TH, Strohsacker MW, Shorr RG, Lefkowitz RJ, Caron MG. Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain. Proceedings of the National Academy of Sciences of the United States of America. 80: 1840-4. PMID 6300875 DOI: 10.1073/pnas.80.7.1840  1
1983 Stiles GL, Hoffman BB, Hubbard M, Caron MG, Lefkowitz RJ. Guanine nucleotides and alpha 1 adrenergic receptors in the heart. Biochemical Pharmacology. 32: 69-71. PMID 6299299 DOI: 10.1016/0006-2952(83)90654-8  0.4
1983 Wikberg JE, Lefkowitz RJ, Caron MG. Solubilization of rat liver alpha 1-adrenergic receptors. Agonist specific alteration in receptor binding affinity. Biochemical Pharmacology. 32: 3171-8. PMID 6139112 DOI: 10.1016/0006-2952(83)90200-9  0.32
1983 Lefkowitz RJ, Stadel JM, Caron MG. Adenylate cyclase-coupled beta-adrenergic receptors: structure and mechanisms of activation and desensitization. Annual Review of Biochemistry. 52: 159-86. PMID 6137187 DOI: 10.1146/ANNUREV.BI.52.070183.001111  0.8
1982 Shorr RG, Heald SL, Jeffs PW, Lavin TN, Strohsacker MW, Lefkowitz RJ, Caron MG. The beta-adrenergic receptor: rapid purification and covalent labeling by photoaffinity crosslinking. Proceedings of the National Academy of Sciences of the United States of America. 79: 2778-82. PMID 6283543 DOI: 10.1073/pnas.79.9.2778  1
1982 Caron MG, Shorr RG, Lavin TN, Lefkowitz RJ. Molecular characterization of the beta-adrenergic receptor of frog erythrocytes. Metabolism: Clinical and Experimental. 31: 658-63. PMID 6283304 DOI: 10.1016/0026-0495(82)90195-0  0.44
1982 Regan JW, Barden N, Lefkowitz RJ, Caron MG, DeMarinis RM, Krog AJ, Holden KG, Matthews WD, Hieble JP. Affinity chromatography of human platelet α 2-adrenergic receptors Proceedings of the National Academy of Sciences of the United States of America. 79: 7223-7227. PMID 6130523 DOI: 10.1073/pnas.79.23.7223  1
1981 Michel T, Hoffman BB, Lefkowitz RJ, Caron MG. Different sedimentation properties of agonist- and antagonist-labelled platelet alpha 2 adrenergic receptors. Biochemical and Biophysical Research Communications. 100: 1131-6. PMID 6268079 DOI: 10.1016/0006-291X(81)91941-0  0.4
1980 Pitha J, Zjawiony J, Lefkowitz RJ, Caron MG. Macromolecular β-adrenergic antagonists discriminating between receptor and antibody Proceedings of the National Academy of Sciences of the United States of America. 77: 2219-2223. PMID 6154947 DOI: 10.1073/PNAS.77.4.2219  1
1980 Pitha J, Zjawiony J, Nasrin N, Lefkowitz RJ, Caron MG. Potent beta-adrenergic antagonist possessing chemically reactive group Life Sciences. 27: 1791-1798. PMID 6110155 DOI: 10.1016/0024-3205(80)90447-6  1
1980 Schocken DD, Caron MG, Lefkowitz RJ. The human placenta--a rich source of beta-adrenergic receptors: characterization of the receptors in particulate and solubilized preparations. The Journal of Clinical Endocrinology and Metabolism. 50: 1082-8. PMID 6103009 DOI: 10.1210/JCEM-50-6-1082  0.72
1979 Caron MG, Limbird LE, Lefkowitz RJ. Biochemical characterization of the beta-adrenergic receptor of the frog erythrocyte. Molecular and Cellular Biochemistry. 28: 45-66. PMID 231201 DOI: 10.1007/BF00223359  1
1979 Wood CL, Caron MG, Lefkowitz RJ. Separation of solubilized alpha and beta adrenergic receptors by affinity chromatography. Biochemical and Biophysical Research Communications. 88: 1-8. PMID 222278 DOI: 10.1016/0006-291X(79)91688-7  1
1977 Kelly PA, Asselin J, Caron MG, Labrie F, Raynaud JP. Potent inhibitory effect of a new antiestrogen (Ru 16117) on the growth of 7, 12-dimethylbenz[a]anthracene-lnduced rat mammary tumors Journal of the National Cancer Institute. 58: 623-628. PMID 402479 DOI: 10.1093/jnci/58.3.623  1
1977 Asselin J, Kelly PA, Caron MG, Labrie F. Control of hormone receptor levels and growth of 7,12-dimethylbenz(a)anthracene-induced mammary tumors by estrogens, progesterone and prolactin Endocrinology. 101: 666-671. PMID 196828 DOI: 10.1210/endo-101-3-666  1
1976 Caron MG, Lefkowitz RJ. Beta-Adrenergic receptors: solubilization of (-)(3H)alprenolol binding sites from frog erythrocyte membranes. Biochemical and Biophysical Research Communications. 68: 315-22. PMID 1082747 DOI: 10.1016/0006-291X(76)91145-1  0.64
1976 Mukherjee C, Caron MG, Lefkowitz RJ. Regulation of adenylate cyclase coupled beta-adrenergic receptors by beta-adrenergic catecholamines. Endocrinology. 99: 347-57. PMID 954636 DOI: 10.1210/endo-99-2-347  0.56
1976 Lefkowitz RJ, Limbird LE, Mukherjee C, Caron MG. The beta-adrenergic receptor and adenylate cyclase. Biochimica Et Biophysica Acta. 457: 1-39. PMID 769837 DOI: 10.1016/0304-4157(76)90012-5  1
1976 Caron MG, Lefkowitz RJ. Biological activity of agarose-immobilized catecholamines. Biochimica Et Biophysica Acta. 444: 472-86. PMID 9146 DOI: 10.1016/0304-4165(76)90391-3  0.68
1975 Mukherjee C, Caron MG, Lefkowitz RJ. Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of beta-adrenergic receptor binding sites. Proceedings of the National Academy of Sciences of the United States of America. 72: 1945-9. PMID 1057183 DOI: 10.1073/pnas.72.5.1945  0.44
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