Bruno Guiard - Publications

Pharmacology EA3544, Châtenay-Malabry, Île-de-France, France 
Electrophysiology microdialysis animal models depression pharmacology

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Faye C, Hen R, Guiard BP, Denny CA, Gardier AM, Mendez-David I, David DJ. Rapid Anxiolytic Effects of RS67333, a Serotonin Type 4 Receptor Agonist, and Diazepam, a Benzodiazepine, Are Mediated by Projections From the Prefrontal Cortex to the Dorsal Raphe Nucleus. Biological Psychiatry. PMID 31623825 DOI: 10.1016/j.biopsych.2019.08.009  0.84
2019 Orrico-Sanchez A, Chausset-Boissarie L, Alves de Sousa R, Coutens B, Rezai Amin S, Vialou V, Louis F, Hessani A, Dansette PM, Zornoza T, Gruszczynski C, Giros B, Guiard BP, Acher F, Pietrancosta N, et al. Antidepressant efficacy of a selective organic cation transporter blocker in a mouse model of depression. Molecular Psychiatry. PMID 31619760 DOI: 10.1038/s41380-019-0548-4  0.32
2019 Zemdegs J, Martin H, Pintana H, Bullich S, Manta S, Marqués MA, Moro C, Layé S, Ducrocq F, Chattipakorn N, Chattipakorn SC, Rampon C, Pénicaud L, Fioramonti X, Guiard BP. Metformin promotes anxiolytic and antidepressant-like responses in insulin-resistant mice by decreasing circulating branched-chain amino acids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31160539 DOI: 10.1523/JNEUROSCI.2904-18.2019  0.44
2019 Rezai Amin S, Gruszczynski C, Guiard BP, Callebert J, Launay JM, Louis F, Betancur C, Vialou V, Gautron S. Viral vector-mediated Cre recombinase expression in substantia nigra induces lesions of the nigrostriatal pathway associated with perturbations of dopamine-related behaviors and hallmarks of programmed cell death. Journal of Neurochemistry. PMID 30748001 DOI: 10.1111/jnc.14684  0.32
2018 Zemdegs J, Rainer Q, Grossmann CP, Rousseau-Ralliard D, Grynberg A, Ribeiro E, Guiard BP. Anxiolytic- and Antidepressant-Like Effects of Fish Oil-Enriched Diet in Brain-Derived Neurotrophic Factor Deficient Mice. Frontiers in Neuroscience. 12: 974. PMID 30622454 DOI: 10.3389/fnins.2018.00974  0.52
2017 Garcia-Garcia AL, Meng Q, Canetta S, Gardier AM, Guiard BP, Kellendonk C, Dranovsky A, Leonardo ED. Serotonin Signaling through Prefrontal Cortex 5-HT1A Receptors during Adolescence Can Determine Baseline Mood-Related Behaviors. Cell Reports. 18: 1144-1156. PMID 28147271 DOI: 10.1016/j.celrep.2017.01.021  0.84
2017 Pham TH, Mendez-David I, Defaix C, Guiard BP, Tritschler L, David DJ, Gardier AM. Ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in BALB/cJ mice. Neuropharmacology. 112: 198-209. PMID 27211253 DOI: 10.1016/j.neuropharm.2016.05.010  0.84
2016 Qesseveur G, Petit AC, Nguyen HT, Dahan L, Colle R, Rotenberg S, Seif I, Robert P, David D, Guilloux JP, Gardier AM, Verstuyft C, Becquemont L, Corruble E, Guiard BP. Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach. Neuropharmacology. 105: 142-53. PMID 26764241 DOI: 10.1016/j.neuropharm.2015.12.022  0.84
2015 Quesseveur G, Portal B, Basile JA, Ezan P, Mathou A, Halley H, Leloup C, Fioramonti X, Déglon N, Giaume C, Rampon C, Guiard BP. Attenuated Levels of Hippocampal Connexin 43 and its Phosphorylation Correlate with Antidepressant- and Anxiolytic-Like Activities in Mice. Frontiers in Cellular Neuroscience. 9: 490. PMID 26733815 DOI: 10.3389/fncel.2015.00490  0.64
2015 Zemdegs J, Quesseveur G, Jarriault D, Pénicaud L, Fioramonti X, Guiard BP. High fat diet-induced metabolic disorders impairs serotonergic function and anxiety-like behaviours in mice. British Journal of Pharmacology. PMID 26472268 DOI: 10.1111/bph.13343  0.64
2015 Guiard BP, Di Giovanni G. Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link? Frontiers in Pharmacology. 6: 46. PMID 25852551 DOI: 10.3389/fphar.2015.00046  0.64
2015 Couroussé T, Bacq A, Belzung C, Guiard B, Balasse L, Louis F, Le Guisquet AM, Gardier AM, Schinkel AH, Giros B, Gautron S. Brain organic cation transporter 2 controls response and vulnerability to stress and GSK3β signaling. Molecular Psychiatry. 20: 889-900. PMID 25092247 DOI: 10.1038/mp.2014.86  0.64
2015 Hache G, Guiard BP, Nguyen TH, Quesseveur G, Gardier AM, Peters D, Munro G, Coudoré F. Antinociceptive activity of the new triple reuptake inhibitor NS18283 in a mouse model of chemotherapy-induced neuropathic pain. European Journal of Pain (London, England). 19: 322-33. PMID 25045036 DOI: 10.1002/ejp.550  0.64
2014 Le Dantec Y, Hache G, Guilloux JP, Guiard BP, David DJ, Adrien J, Escourrou P. NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration. Neuroscience. 274: 357-68. PMID 24909899 DOI: 10.1016/j.neuroscience.2014.05.050  0.84
2014 Petit AC, Quesseveur G, Gressier F, Colle R, David DJ, Gardier AM, Ferreri F, Lépine JP, Falissard B, Verstuyft C, Guiard BP, Corruble E. Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 54: 76-82. PMID 24801750 DOI: 10.1016/j.pnpbp.2014.04.013  0.84
2013 Quesseveur G, Gardier AM, Guiard BP. The monoaminergic tripartite synapse: a putative target for currently available antidepressant drugs. Current Drug Targets. 14: 1277-94. PMID 24020973  0.84
2013 Guilloux JP, Mendez-David I, Pehrson A, Guiard BP, Repérant C, Orvoën S, Gardier AM, Hen R, Ebert B, Miller S, Sanchez C, David DJ. Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. Neuropharmacology. 73: 147-59. PMID 23721744 DOI: 10.1016/j.neuropharm.2013.05.014  0.84
2013 Quesseveur G, David DJ, Gaillard MC, Pla P, Wu MV, Nguyen HT, Nicolas V, Auregan G, David I, Dranovsky A, Hantraye P, Hen R, Gardier AM, Déglon N, Guiard BP. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational Psychiatry. 3: e253. PMID 23632457 DOI: 10.1038/tp.2013.30  0.84
2013 Quesseveur G, Repérant C, David DJ, Gardier AM, Sanchez C, Guiard BP. 5-HT₂A receptor inactivation potentiates the acute antidepressant-like activity of escitalopram: involvement of the noradrenergic system. Experimental Brain Research. 226: 285-95. PMID 23411676 DOI: 10.1007/s00221-013-3434-3  0.84
2013 Nguyen HT, Guiard BP, Bacq A, David DJ, David I, Quesseveur G, Gautron S, Sanchez C, Gardier AM. Blockade of the high-affinity noradrenaline transporter (NET) by the selective 5-HT reuptake inhibitor escitalopram: an in vivo microdialysis study in mice. British Journal of Pharmacology. 168: 103-16. PMID 22233336 DOI: 10.1111/j.1476-5381.2012.01850.x  0.84
2013 Guiard B. Glia: A new cellular target in the treatment of major depression Current Drug Targets. 14: 1.  0.64
2012 Quesseveur G, Nguyen HT, Gardier AM, Guiard BP. 5-HT2 ligands in the treatment of anxiety and depression. Expert Opinion On Investigational Drugs. 21: 1701-25. PMID 22917059 DOI: 10.1517/13543784.2012.719872  0.84
2012 Hache G, Guiard BP, Le Dantec Y, Orvoën S, David DJ, Gardier AM, Coudoré F. Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression. Neuroreport. 23: 525-9. PMID 22555563 DOI: 10.1097/WNR.0b013e328353d70a  0.84
2012 Rainer Q, Nguyen HT, Quesseveur G, Gardier AM, David DJ, Guiard BP. Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration. Molecular Pharmacology. 81: 106-12. PMID 22031471 DOI: 10.1124/mol.111.075796  0.84
2012 Bacq A, Balasse L, Biala G, Guiard B, Gardier AM, Schinkel A, Louis F, Vialou V, Martres MP, Chevarin C, Hamon M, Giros B, Gautron S. Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response. Molecular Psychiatry. 17: 926-39. PMID 21769100 DOI: 10.1038/mp.2011.87  0.64
2012 Guiard BP, Mansari ME, Murphy DL, Blier P. Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: an electrophysiological and neurochemical study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 349-61. PMID 21439106 DOI: 10.1017/S1461145711000484  0.64
2011 Richardson-Jones JW, Craige CP, Nguyen TH, Kung HF, Gardier AM, Dranovsky A, David DJ, Guiard BP, Beck SG, Hen R, Leonardo ED. Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6008-18. PMID 21508226 DOI: 10.1523/JNEUROSCI.5836-10.2011  0.84
2011 Guilloux JP, David DJ, Xia L, Nguyen HT, Rainer Q, Guiard BP, Repérant C, Deltheil T, Toth M, Hen R, Gardier AM. Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments. Neuropharmacology. 61: 478-88. PMID 21333660 DOI: 10.1016/j.neuropharm.2011.02.009  0.84
2011 Guiard BP, Chenu F, El Mansari M, Blier P. Characterization of the electrophysiological properties of triple reuptake inhibitors on monoaminergic neurons. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 211-23. PMID 20149268 DOI: 10.1017/S1461145710000076  0.64
2011 Hache G, Coudore F, Gardier AM, Guiard BP. Monoaminergic antidepressants in the relief of pain: Potential therapeutic utility of triple reuptake inhibitors (TRIs) Pharmaceuticals. 4: 285-342. DOI: 10.3390/ph4020285  0.64
2010 Barik J, Parnaudeau S, Saint Amaux AL, Guiard BP, Golib Dzib JF, Bocquet O, Bailly A, Benecke A, Tronche F. Glucocorticoid receptors in dopaminoceptive neurons, key for cocaine, are dispensable for molecular and behavioral morphine responses. Biological Psychiatry. 68: 231-9. PMID 20554270 DOI: 10.1016/j.biopsych.2010.03.037  0.64
2010 El Mansari M, Guiard BP, Chernoloz O, Ghanbari R, Katz N, Blier P. Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder. Cns Neuroscience & Therapeutics. 16: e1-17. PMID 20406250 DOI: 10.1111/j.1755-5949.2010.00146.x  0.64
2010 Richardson-Jones JW, Craige CP, Guiard BP, Stephen A, Metzger KL, Kung HF, Gardier AM, Dranovsky A, David DJ, Beck SG, Hen R, Leonardo ED. 5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants. Neuron. 65: 40-52. PMID 20152112 DOI: 10.1016/j.neuron.2009.12.003  0.84
2010 Popa D, Cerdan J, Repérant C, Guiard BP, Guilloux JP, David DJ, Gardier AM. A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain. European Journal of Pharmacology. 628: 83-90. PMID 19944680 DOI: 10.1016/j.ejphar.2009.11.037  0.84
2010 Katz NS, Guiard BP, El Mansari M, Blier P. Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons. Journal of Psychopharmacology (Oxford, England). 24: 1223-35. PMID 19939862 DOI: 10.1177/0269881109348178  0.64
2009 Guiard BP, El Mansari M, Blier P. Prospect of a dopamine contribution in the next generation of antidepressant drugs: the triple reuptake inhibitors. Current Drug Targets. 10: 1069-84. PMID 19702555 DOI: 10.2174/138945009789735156  0.64
2009 David DJ, Samuels BA, Rainer Q, Wang JW, Marsteller D, Mendez I, Drew M, Craig DA, Guiard BP, Guilloux JP, Artymyshyn RP, Gardier AM, Gerald C, Antonijevic IA, Leonardo ED, et al. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron. 62: 479-93. PMID 19477151 DOI: 10.1016/j.neuron.2009.04.017  0.84
2009 Gardier AM, Guiard BP, Guilloux JP, Repérant C, Coudoré F, David DJ. Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review. Fundamental & Clinical Pharmacology. 23: 23-42. PMID 19267769 DOI: 10.1111/j.1472-8206.2008.00640.x  0.84
2008 Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka KF, Repérant C, Guilloux JP, Coudoré F, Hen R, Gardier AM. Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. Neuropharmacology. 55: 1006-14. PMID 18761360 DOI: 10.1016/j.neuropharm.2008.08.001  0.84
2008 Guiard BP, El Mansari M, Blier P. Cross-talk between dopaminergic and noradrenergic systems in the rat ventral tegmental area, locus ceruleus, and dorsal hippocampus. Molecular Pharmacology. 74: 1463-75. PMID 18703671 DOI: 10.1124/mol.108.048033  0.64
2008 Guiard BP, El Mansari M, Merali Z, Blier P. Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 625-39. PMID 18205979 DOI: 10.1017/S1461145707008383  0.64
2008 Deltheil T, Guiard BP, Guilloux JP, Nicolas L, Deloménie C, Repérant C, Le Maitre E, Leroux-Nicollet I, Benmansour S, Coudoré F, David DJ, Gardier AM. Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus. Pharmacology, Biochemistry, and Behavior. 90: 174-83. PMID 17980409 DOI: 10.1016/j.pbb.2007.09.018  0.84
2008 Guiard BP, David DJ, Deltheil T, Chenu F, Le Maître E, Renoir T, Leroux-Nicollet I, Sokoloff P, Lanfumey L, Hamon M, Andrews AM, Hen R, Gardier AM. Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. The International Journal of Neuropsychopharmacology. 11: 79-92. PMID 17559709 DOI: 10.1017/S1461145707007857  0.84
2007 Guiard BP, Guilloux JP, Reperant C, Hunt SP, Toth M, Gardier AM. Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex. Molecular Pharmacology. 72: 1411-8. PMID 17890358 DOI: 10.1124/mol.107.040113  0.84
2006 Molles BE, Maskos U, Pons S, Besson M, Guiard P, Guilloux JP, Evrard A, Cormier A, Mameli-Engvall M, Cloëz-Tayarani I, Nakatani H, Dufour N, Bemelmans AP, Mallet J, Cazala P, et al. Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors. Journal of Molecular Neuroscience : Mn. 30: 105-6. PMID 17192649 DOI: 10.1385/JMN:30:1:105  0.64
2006 Chenu F, Guiard BP, Bourin M, Gardier AM. Antidepressant-like activity of selective serotonin reuptake inhibitors combined with a NK1 receptor antagonist in the mouse forced swimming test. Behavioural Brain Research. 172: 256-63. PMID 16806519 DOI: 10.1016/j.bbr.2006.05.011  0.64
2006 Guiard BP, Lanfumey L, Gardier AM. Microdialysis approach to study serotonin outflow in mice following selective serotonin reuptake inhibitors and substance P (neurokinin 1) receptor antagonist administration: a review. Current Drug Targets. 7: 187-201. PMID 16475960  0.84
2006 Guilloux JP, David DJ, Guiard BP, Chenu F, Repérant C, Toth M, Bourin M, Gardier AM. Blockade of 5-HT1A receptors by (+/-)-pindolol potentiates cortical 5-HT outflow, but not antidepressant-like activity of paroxetine: microdialysis and behavioral approaches in 5-HT1A receptor knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2162-72. PMID 16452992 DOI: 10.1038/sj.npp.1301019  0.84
2005 Guiard BP, Froger N, Hamon M, Gardier AM, Lanfumey L. Sustained pharmacological blockade of NK1 substance P receptors causes functional desensitization of dorsal raphe 5-HT 1A autoreceptors in mice. Journal of Neurochemistry. 95: 1713-23. PMID 16219031 DOI: 10.1111/j.1471-4159.2005.03488.x  0.84
2005 Maskos U, Molles BE, Pons S, Besson M, Guiard BP, Guilloux JP, Evrard A, Cazala P, Cormier A, Mameli-Engvall M, Dufour N, Cloëz-Tayarani I, Bemelmans AP, Mallet J, Gardier AM, et al. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature. 436: 103-7. PMID 16001069 DOI: 10.1038/nature03694  0.64
2004 Bert L, Favale D, Jego G, Greve P, Guilloux JP, Guiard BP, Gardier AM, Suaud-Chagny MF, Lestage P. Rapid and precise method to locate microdialysis probe implantation in the rodent brain. Journal of Neuroscience Methods. 140: 53-7. PMID 15589334 DOI: 10.1016/j.jneumeth.2004.04.042  0.64
2004 David DJ, Froger N, Guiard B, Przybylski C, Jego G, Boni C, Hunt SP, De Felipe C, Hamon M, Jacquot C, Gardier AM, Lanfumey L. Serotonin transporter in substance P (neurokinin 1) receptor knock-out mice. European Journal of Pharmacology. 492: 41-8. PMID 15145704 DOI: 10.1016/j.ejphar.2004.03.016  0.84
2004 Guiard BP, Przybylski C, Guilloux JP, Seif I, Froger N, De Felipe C, Hunt SP, Lanfumey L, Gardier AM. Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. Journal of Neurochemistry. 89: 54-63. PMID 15030389 DOI: 10.1046/j.1471-4159.2003.02304.x  0.84
2002 Coelho A, Vergnolle N, Guiard B, Fioramonti J, Bueno L. Proteinases and proteinase-activated receptor 2: A possible role to promote visceral hyperalgesia in rats Gastroenterology. 122: 1035-1047. PMID 11910355  0.64
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