BethAnn McLaughlin - Publications

Affiliations: 
Neurology Vanderbilt University, Nashville, TN 
Area:
Cell Death, Ischemia, Neuroprotection, Stroke, Parkinsons Disease
Website:
http://www.mc.vanderbilt.edu/root/vumc.php?site=mclaughlinlab

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... McLaughlin B, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.496
2019 Musiek ES, Brooks JD, Joo M, Brunoldi E, Porta A, Zanoni G, Vidari G, Blackwell TS, Montine TJ, Milne GL, McLaughlin B, Morrow JD. Correction: Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the ω -3 polyunsaturated fatty acid docosahexaenoic acid. The Journal of Biological Chemistry. 294: 6657. PMID 31003972 DOI: 10.1074/jbc.AAC119.008639  0.737
2018 Lizama BN, Palubinsky AM, Raveendran VA, Moore AM, Federspiel JD, Codreanu SG, Liebler DC, McLaughlin B. Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29934347 DOI: 10.1523/Jneurosci.0699-18.2018  0.805
2017 Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, ... ... McLaughlin B, et al. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death and Differentiation. PMID 29229998 DOI: 10.1038/S41418-017-0020-4  0.481
2017 Lizama BN, Palubinsky AM, McLaughlin B. Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues. Neurochemistry International. PMID 28851515 DOI: 10.1016/J.Neuint.2017.08.013  0.764
2016 Morales Betanzos C, Federspiel JD, Palubinsky AM, McLaughlin B, Liebler DC. Dynamic Phosphorylation of Apoptosis Signal Regulating Kinase 1 (ASK1) in Response to Oxidative and Electrophilic Stress. Chemical Research in Toxicology. 29: 2175-2183. PMID 27989136 DOI: 10.1021/Acs.Chemrestox.6B00339  0.359
2016 Lizama-Manibusan BN, Klein S, McKenzie JR, Cliffel DE, McLaughlin B. Analysis of a Nitroreductase-based Hypoxia Sensor in Primary Neuronal Cultures. Acs Chemical Neuroscience. PMID 27504748 DOI: 10.1021/Acschemneuro.6B00215  0.419
2016 Federspiel JD, Codreanu SG, Palubinsky AM, Winland AJ, Morales Betanzos C, McLaughlin B, Liebler DC. Assembly dynamics and stoichiometry of the apoptosis signal-regulating kinase (ASK) signalosome in response to electrophile stress. Molecular & Cellular Proteomics : McP. PMID 27006476 DOI: 10.1074/Mcp.M115.057364  0.346
2015 Palubinsky AM, Stankowski JN, Kale AC, Codreanu SG, Singer RJ, Liebler DC, Stanwood GD, McLaughlin B. CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling. Antioxidants & Redox Signaling. PMID 25602369 DOI: 10.1089/Ars.2014.6102  0.771
2014 Naik M, Humnabadkar V, Tantry SJ, Panda M, Narayan A, Guptha S, Panduga V, Manjrekar P, Jena LK, Koushik K, Shanbhag G, Jatheendranath S, Manjunatha MR, Gorai G, Bathula C, ... ... McLaughlin B, et al. 4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity. Journal of Medicinal Chemistry. 57: 5419-34. PMID 24871036 DOI: 10.1021/Jm5005978  0.512
2013 Lizama-Manibusan B, McLaughlin B. Redox modification of proteins as essential mediators of CNS autophagy and mitophagy. Febs Letters. 587: 2291-8. PMID 23773928 DOI: 10.1016/J.Febslet.2013.06.007  0.406
2013 Grelli KN, Palubinsky AM, Kale AC, Lizama-Manibusan BN, Stankowski JN, Milne GL, Singer R, McLaughlin B. Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation. Cns & Neurological Disorders Drug Targets. 12: 849-60. PMID 23469839 DOI: 10.2174/18715273113129990062  0.76
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... McLaughlin B, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.491
2012 McKenzie JR, Palubinsky AM, Brown JE, McLaughlin B, Cliffel DE. Metabolic multianalyte microphysiometry reveals extracellular acidosis is an essential mediator of neuronal preconditioning. Acs Chemical Neuroscience. 3: 510-8. PMID 22860220 DOI: 10.1021/Cn300003R  0.444
2012 McLaughlin B, Buendia MA, Saborido TP, Palubinsky AM, Stankowski JN, Stanwood GD. Haploinsufficiency of the E3 ubiquitin ligase C-terminus of heat shock cognate 70 interacting protein (CHIP) produces specific behavioral impairments. Plos One. 7: e36340. PMID 22606257 DOI: 10.1371/Journal.Pone.0036340  0.728
2012 Palubinsky AM, Martin JA, McLaughlin B. The role of central nervous system development in late-onset neurodegenerative disorders. Developmental Neuroscience. 34: 129-39. PMID 22572535 DOI: 10.1159/000336828  0.423
2012 Albers E, Donahue BS, Milne G, Saville BR, Wang W, Bichell D, McLaughlin B. Perioperative plasma F(2)-Isoprostane levels correlate with markers of impaired ventilation in infants with single-ventricle physiology undergoing stage 2 surgical palliation on the cardiopulmonary bypass. Pediatric Cardiology. 33: 562-8. PMID 22327227 DOI: 10.1007/S00246-012-0166-2  0.58
2011 Brooks JD, Musiek ES, Koestner TR, Stankowski JN, Howard JR, Brunoldi EM, Porta A, Zanoni G, Vidari G, Morrow JD, Milne GL, McLaughlin B. The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation. Journal of Neurochemistry. 119: 604-16. PMID 21838782 DOI: 10.1111/J.1471-4159.2011.07422.X  0.754
2011 Zeiger SL, Stankowski JN, McLaughlin B. Assessing neuronal bioenergetic status. Methods in Molecular Biology (Clifton, N.J.). 758: 215-35. PMID 21815069 DOI: 10.1007/978-1-61779-170-3_15  0.787
2011 Stankowski JN, Zeiger SL, Cohen EL, DeFranco DB, Cai J, McLaughlin B. C-terminus of heat shock cognate 70 interacting protein increases following stroke and impairs survival against acute oxidative stress. Antioxidants & Redox Signaling. 14: 1787-801. PMID 20677910 DOI: 10.1089/Ars.2010.3300  0.786
2011 Stankowski JN, Codreanu SG, Liebler DC, McLaughlin B. Analysis of protein targets by oxidative stress using the OxyBlot and biotin-avidin-capture methodology Neuromethods. 56: 365-381. DOI: 10.1007/978-1-61779-077-5_18  0.712
2010 Kleman AM, Brown JE, Zeiger SL, Hettinger JC, Brooks JD, Holt B, Morrow JD, Musiek ES, Milne GL, McLaughlin B. p66(shc)'s role as an essential mitophagic molecule in controlling neuronal redox and energetic tone. Autophagy. 6: 948-9. PMID 20724835 DOI: 10.4161/Auto.6.7.13007  0.774
2010 Zeiger SL, McKenzie JR, Stankowski JN, Martin JA, Cliffel DE, McLaughlin B. Neuron specific metabolic adaptations following multi-day exposures to oxygen glucose deprivation. Biochimica Et Biophysica Acta. 1802: 1095-104. PMID 20656023 DOI: 10.1016/J.Bbadis.2010.07.013  0.802
2010 Brown JE, Zeiger SL, Hettinger JC, Brooks JD, Holt B, Morrow JD, Musiek ES, Milne G, McLaughlin B. Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5242-52. PMID 20392947 DOI: 10.1523/Jneurosci.6366-09.2010  0.786
2010 Albers EL, Bichell DP, McLaughlin B. New approaches to neuroprotection in infant heart surgery. Pediatric Research. 68: 1-9. PMID 20351657 DOI: 10.1203/Pdr.0B013E3181Df5402  0.568
2009 Zeiger SL, Musiek ES, Zanoni G, Vidari G, Morrow JD, Milne GJ, McLaughlin B. Neurotoxic lipid peroxidation species formed by ischemic stroke increase injury. Free Radical Biology & Medicine. 47: 1422-31. PMID 19699297 DOI: 10.1016/J.Freeradbiomed.2009.08.011  0.796
2009 Stanwood GD, Leitch DB, Savchenko V, Wu J, Fitsanakis VA, Anderson DJ, Stankowski JN, Aschner M, McLaughlin B. Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia. Journal of Neurochemistry. 110: 378-89. PMID 19457100 DOI: 10.1111/J.1471-4159.2009.06145.X  0.793
2008 Musiek ES, Brooks JD, Joo M, Brunoldi E, Porta A, Zanoni G, Vidari G, Blackwell TS, Montine TJ, Milne GL, McLaughlin B, Morrow JD. Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid. The Journal of Biological Chemistry. 283: 19927-35. PMID 18490445 DOI: 10.1074/Jbc.M803625200  0.76
2008 Stankowski J, Leitch D, Aschner M, McLaughlin B, Stanwood GD. Selective vulnerability of dopaminergic systems to Manganese: Relevance to occupational exposure Neurotoxicology and Teratology. 30: 259. DOI: 10.1016/J.Ntt.2008.03.056  0.745
2007 Musiek ES, McLaughlin B, Morrow JD. Electrophilic cyclopentenone isoprostanes in neurodegeneration. Journal of Molecular Neuroscience : Mn. 33: 80-6. PMID 17901550 DOI: 10.1007/S12031-007-0042-3  0.685
2007 Altay T, McLaughlin B, Wu JY, Park TS, Gidday JM. Slit modulates cerebrovascular inflammation and mediates neuroprotection against global cerebral ischemia. Experimental Neurology. 207: 186-94. PMID 17714707 DOI: 10.1016/J.Expneurol.2007.06.028  0.441
2007 Jiang GC, Tidwell K, McLaughlin BA, Cai J, Gupta RC, Milatovic D, Nass R, Aschner M. Neurotoxic potential of depleted uranium effects in primary cortical neuron cultures and in Caenorhabditis elegans. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 553-65. PMID 17636247 DOI: 10.1093/Toxsci/Kfm171  0.3
2007 O'Duffy AE, Bordelon YM, McLaughlin B. Killer proteases and little strokes--how the things that do not kill you make you stronger. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 655-68. PMID 16896349 DOI: 10.1038/Sj.Jcbfm.9600380  0.365
2006 Musiek ES, Breeding RS, Milne GL, Zanoni G, Morrow JD, McLaughlin B. Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration. Journal of Neurochemistry. 97: 1301-13. PMID 16638022 DOI: 10.1111/J.1471-4159.2006.03797.X  0.695
2006 MILNE G, MUSIEK E, ZANONI G, VIDARI G, MCLAUGHLIN B, MORROW J. PII-5Development of a novel liquid chromatography-mass spectrometric assay to measure formation of highly reactive cyclopentenone isoprostanes in vivo Clinical Pharmacology & Therapeutics. 79: P36-P36. DOI: 10.1016/J.Clpt.2005.12.130  0.521
2005 Musiek ES, Milne GL, McLaughlin B, Morrow JD. Cyclopentenone eicosanoids as mediators of neurodegeneration: a pathogenic mechanism of oxidative stress-mediated and cyclooxygenase-mediated neurotoxicity. Brain Pathology (Zurich, Switzerland). 15: 149-58. PMID 15912888 DOI: 10.1111/J.1750-3639.2005.Tb00512.X  0.617
2004 McLaughlin B. The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling. Apoptosis : An International Journal On Programmed Cell Death. 9: 111-21. PMID 15004508 DOI: 10.1023/B:Appt.0000018793.10779.Dc  0.329
2003 McLaughlin B, Hartnett KA, Erhardt JA, Legos JJ, White RF, Barone FC, Aizenman E. Caspase 3 activation is essential for neuroprotection in preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 100: 715-20. PMID 12522260 DOI: 10.1073/Pnas.0232966100  0.653
2002 Leszkiewicz DN, McLaughlin BA, Aizenman E. Protein kinases and light: unlikely partners in a receptor localization puzzle. Physiology & Behavior. 77: 533-6. PMID 12526995 DOI: 10.1016/S0031-9384(02)00911-3  0.765
2002 Du S, McLaughlin B, Pal S, Aizenman E. In vitro neurotoxicity of methylisothiazolinone, a commonly used industrial and household biocide, proceeds via a zinc and extracellular signal-regulated kinase mitogen-activated protein kinase-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7408-16. PMID 12196562 DOI: 10.1523/Jneurosci.22-17-07408.2002  0.71
2002 Legos JJ, McLaughlin B, Skaper SD, Strijbos PJ, Parsons AA, Aizenman E, Herin GA, Barone FC, Erhardt JA. The selective p38 inhibitor SB-239063 protects primary neurons from mild to moderate excitotoxic injury. European Journal of Pharmacology. 447: 37-42. PMID 12106800 DOI: 10.1016/S0014-2999(02)01890-3  0.784
2001 McLaughlin B, Pal S, Tran MP, Parsons AA, Barone FC, Erhardt JA, Aizenman E. p38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3303-11. PMID 11331359 DOI: 10.1523/Jneurosci.21-10-03303.2001  0.662
2001 Nuttall ME, Lee D, McLaughlin B, Erhardt JA. Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies. Drug Discovery Today. 6: 85-91. PMID 11166256 DOI: 10.1016/S1359-6446(00)01601-9  0.307
2000 Aizenman E, Stout AK, Hartnett KA, Dineley KE, McLaughlin B, Reynolds IJ. Induction of neuronal apoptosis by thiol oxidation: putative role of intracellular zinc release. Journal of Neurochemistry. 75: 1878-88. PMID 11032877 DOI: 10.1046/J.1471-4159.2000.0751878.X  0.801
2000 Hoyt KR, McLaughlin BA, Higgins DS, Reynolds IJ. Inhibition of glutamate-induced mitochondrial depolarization by tamoxifen in cultured neurons. The Journal of Pharmacology and Experimental Therapeutics. 293: 480-6. PMID 10773018  0.767
1998 McLaughlin BA, Nelson D, Silver IA, Erecinska M, Chesselet MF. Methylmalonate toxicity in primary neuronal cultures. Neuroscience. 86: 279-90. PMID 9692761 DOI: 10.1016/S0306-4522(97)00594-0  0.762
1998 McLaughlin BA, Nelson D, EreciÅ„ska M, Chesselet MF. Toxicity of dopamine to striatal neurons in vitro and potentiation of cell death by a mitochondrial inhibitor. Journal of Neurochemistry. 70: 2406-15. PMID 9603205 DOI: 10.1046/J.1471-4159.1998.70062406.X  0.581
1995 Robinson MB, Hopkins K, Batshaw ML, McLaughlin BA, Heyes MP, Oster-Granite ML. Evidence of excitotoxicity in the brain of the ornithine carbamoyltransferase deficient sparse fur mouse. Brain Research. Developmental Brain Research. 90: 35-44. PMID 8777776 DOI: 10.1016/0165-3806(96)83484-5  0.451
1995 Batshaw ML, Yudkoff M, McLaughlin BA, Gorry E, Anegawa NJ, Smith IA, Hyman SL, Robinson MB. The sparse fur mouse as a model for gene therapy in ornithine carbamoyltransferase deficiency. Gene Therapy. 2: 743-9. PMID 8750014  0.402
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