| Year |
Citation |
Score |
| 2018 |
Amtul Z, Uhrig M, Wang L, Rozmahel RF, Beyreuther K. Corrigendum to "Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight" [Neurobiol. Aging 33 (2012) 831.e21-831.e31]. Neurobiology of Aging. 62: 247. PMID 29277188 DOI: 10.1016/J.Neurobiolaging.2017.12.007 |
0.314 |
|
| 2014 |
Rupp C, Beyreuther K, Maurer K, Kins S. A presenilin 1 mutation in the first case of Alzheimer's disease: revisited. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 869-72. PMID 25130656 DOI: 10.1016/J.Jalz.2014.06.005 |
0.387 |
|
| 2012 |
Amtul Z, Uhrig M, Wang L, Rozmahel RF, Beyreuther K. Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight. Neurobiology of Aging. 33: 831.e21-31. PMID 21920632 DOI: 10.1016/J.Neurobiolaging.2011.07.014 |
0.509 |
|
| 2011 |
Amtul Z, Uhrig M, Beyreuther K. Additive effects of fatty acid mixtures on the levels and ratio of amyloid β40/42 peptides differ from the effects of individual fatty acids. Journal of Neuroscience Research. 89: 1795-801. PMID 21748777 DOI: 10.1002/Jnr.22706 |
0.379 |
|
| 2011 |
Amtul Z, Uhrig M, Rozmahel RF, Beyreuther K. Structural insight into the differential effects of omega-3 and omega-6 fatty acids on the production of Abeta peptides and amyloid plaques. The Journal of Biological Chemistry. 286: 6100-7. PMID 20971855 DOI: 10.1074/Jbc.M110.183608 |
0.469 |
|
| 2011 |
Masters CL, Beyreuther K. Amyloid-β Production Neurodegeneration: the Molecular Pathology of Dementia and Movement Disorders: Second Edition. 92-96. DOI: 10.1002/9781444341256.ch11 |
0.354 |
|
| 2010 |
Amtul Z, Uhrig M, Supino R, Beyreuther K. Phospholipids and a phospholipid-rich diet alter the in vitro amyloid-beta peptide levels and amyloid-beta 42/40 ratios. Neuroscience Letters. 481: 73-7. PMID 20600609 DOI: 10.1016/J.Neulet.2010.06.046 |
0.49 |
|
| 2009 |
Szodorai A, Kuan YH, Hunzelmann S, Engel U, Sakane A, Sasaki T, Takai Y, Kirsch J, Müller U, Beyreuther K, Brady S, Morfini G, Kins S. APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14534-44. PMID 19923287 DOI: 10.1523/Jneurosci.1546-09.2009 |
0.449 |
|
| 2009 |
Lv J, Jia H, Jiang Y, Ruan Y, Liu Z, Yue W, Beyreuther K, Tu P, Zhang D. Tenuifolin, an extract derived from tenuigenin, inhibits amyloid-beta secretion in vitro. Acta Physiologica (Oxford, England). 196: 419-25. PMID 19208093 DOI: 10.1111/j.1748-1716.2009.01961.x |
0.332 |
|
| 2008 |
Radzimanowski J, Simon B, Sattler M, Beyreuther K, Sinning I, Wild K. Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2. Embo Reports. 9: 1134-40. PMID 18833287 DOI: 10.1038/Embor.2008.188 |
0.445 |
|
| 2008 |
Radzimanowski J, Ravaud S, Schlesinger S, Koch J, Beyreuther K, Sinning I, Wild K. Crystal structure of the human Fe65-PTB1 domain. The Journal of Biological Chemistry. 283: 23113-20. PMID 18550529 DOI: 10.1074/Jbc.M800861200 |
0.339 |
|
| 2008 |
Wun KS, Miles LA, Crespi GA, Wycherley K, Ascher DB, Barnham KJ, Cappai R, Beyreuther K, Masters CL, Parker MW, McKinstry WJ. Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 438-41. PMID 18453721 DOI: 10.1107/S1744309108011718 |
0.507 |
|
| 2008 |
Radzimanowski J, Beyreuther K, Sinning I, Wild K. Overproduction, purification, crystallization and preliminary X-ray analysis of human Fe65-PTB2 in complex with the amyloid precursor protein intracellular domain. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 409-12. PMID 18453713 DOI: 10.1107/S1744309108009524 |
0.413 |
|
| 2008 |
Grimm MO, Grimm HS, Tomic I, Beyreuther K, Hartmann T, Bergmann C. Independent inhibition of Alzheimer disease beta- and gamma-secretase cleavage by lowered cholesterol levels. The Journal of Biological Chemistry. 283: 11302-11. PMID 18308724 DOI: 10.1074/Jbc.M801520200 |
0.526 |
|
| 2008 |
Miles LA, Wun KS, Crespi GA, Fodero-Tavoletti MT, Galatis D, Bagley CJ, Beyreuther K, Masters CL, Cappai R, McKinstry WJ, Barnham KJ, Parker MW. Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. Journal of Molecular Biology. 377: 181-92. PMID 18237744 DOI: 10.1016/J.Jmb.2007.12.036 |
0.537 |
|
| 2007 |
Back S, Haas P, Tschäpe JA, Gruebl T, Kirsch J, Müller U, Beyreuther K, Kins S. beta-amyloid precursor protein can be transported independent of any sorting signal to the axonal and dendritic compartment. Journal of Neuroscience Research. 85: 2580-90. PMID 17335075 DOI: 10.1002/Jnr.21239 |
0.353 |
|
| 2007 |
Rusu P, Jansen A, Soba P, Kirsch J, Löwer A, Merdes G, Kuan YH, Jung A, Beyreuther K, Kjaerulff O, Kins S. Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity. The European Journal of Neuroscience. 25: 1079-86. PMID 17331204 DOI: 10.1111/J.1460-9568.2007.05341.X |
0.815 |
|
| 2007 |
Kins S, Szodorai A, Kuan Y, Kirsch J, Müller U, Beyreuther K, Morfini G, Brady S. Intraneuronal traffic of the Amyloid Precursor Protein Gbm Fall Meeting Hamburg 2007. 2007. DOI: 10.1240/sav_gbm_2007_h_001824 |
0.34 |
|
| 2006 |
Kuan YH, Gruebl T, Soba P, Eggert S, Nesic I, Back S, Kirsch J, Beyreuther K, Kins S. PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2. The Journal of Biological Chemistry. 281: 40114-23. PMID 17050537 DOI: 10.1074/Jbc.M605407200 |
0.828 |
|
| 2006 |
Kins S, Lauther N, Szodorai A, Beyreuther K. Subcellular trafficking of the amyloid precursor protein gene family and its pathogenic role in Alzheimer's disease. Neuro-Degenerative Diseases. 3: 218-26. PMID 17047360 DOI: 10.1159/000095259 |
0.371 |
|
| 2006 |
Masters CL, Beyreuther K. Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the Abeta amyloid pathway. Brain : a Journal of Neurology. 129: 2823-39. PMID 17012295 DOI: 10.1093/Brain/Awl251 |
0.548 |
|
| 2006 |
Liu Z, Ruan Y, Yue W, Zhu Z, Hartmann T, Beyreuther K, Zhang D. GM1 up-regulates Ubiquilin 1 expression in human neuroblastoma cells and rat cortical neurons. Neuroscience Letters. 407: 59-63. PMID 16949204 DOI: 10.1016/j.neulet.2006.08.005 |
0.393 |
|
| 2006 |
Masters CL, Beyreuther K. Pathways to the discovery of the Abeta amyloid of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 9: 155-61. PMID 16914854 DOI: 10.3233/Jad-2006-9S318 |
0.606 |
|
| 2006 |
Kwak YD, Brannen CL, Qu T, Kim HM, Dong X, Soba P, Majumdar A, Kaplan A, Beyreuther K, Sugaya K. Amyloid precursor protein regulates differentiation of human neural stem cells. Stem Cells and Development. 15: 381-9. PMID 16846375 DOI: 10.1089/Scd.2006.15.381 |
0.838 |
|
| 2006 |
Barnham KJ, Cappai R, Beyreuther K, Masters CL, Hill AF. Delineating common molecular mechanisms in Alzheimer's and prion diseases. Trends in Biochemical Sciences. 31: 465-72. PMID 16820299 DOI: 10.1016/J.Tibs.2006.06.006 |
0.555 |
|
| 2006 |
Kins S, Rusu P, Jansen A, Soba P, Merdes G, Kuan Y, Jung A, Beyreuther K, Kjaerulff O. O4-02-01: Altered expression of APP gene family members in Drosophila cause defects in axonal transport and affect synaptic plasticity Alzheimer's & Dementia. 2: S77-S77. DOI: 10.1016/J.Jalz.2006.05.300 |
0.768 |
|
| 2006 |
Masters CL, Beyreuther K. Pathways to the discovery of the Aß amyloid of Alzheimer's disease Alzheimer's Disease: a Century of Scientific and Clinical Research. 155-161. |
0.504 |
|
| 2005 |
Soba P, Eggert S, Wagner K, Zentgraf H, Siehl K, Kreger S, Löwer A, Langer A, Merdes G, Paro R, Masters CL, Müller U, Kins S, Beyreuther K. Homo- and heterodimerization of APP family members promotes intercellular adhesion. The Embo Journal. 24: 3624-34. PMID 16193067 DOI: 10.1038/Sj.Emboj.7600824 |
0.816 |
|
| 2005 |
Masters CL, Beyreuther K. The neuropathology of Alzheimer's disease in the year 2005 Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics. 433-440. DOI: 10.1017/CBO9780511544873.030 |
0.432 |
|
| 2004 |
Merdes G, Soba P, Loewer A, Bilic MV, Beyreuther K, Paro R. Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila. The Embo Journal. 23: 4082-95. PMID 15385958 DOI: 10.1038/Sj.Emboj.7600413 |
0.825 |
|
| 2004 |
Jia H, Jiang Y, Ruan Y, Zhang Y, Ma X, Zhang J, Beyreuther K, Tu P, Zhang D. Tenuigenin treatment decreases secretion of the Alzheimer's disease amyloid beta-protein in cultured cells. Neuroscience Letters. 367: 123-8. PMID 15308312 DOI: 10.1016/J.Neulet.2004.05.093 |
0.492 |
|
| 2004 |
Barnham KJ, Haeffner F, Ciccotosto GD, Curtain CC, Tew D, Mavros C, Beyreuther K, Carrington D, Masters CL, Cherny RA, Cappai R, Bush AI. Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1427-9. PMID 15231727 DOI: 10.1096/Fj.04-1890Fje |
0.596 |
|
| 2004 |
George AJ, Holsinger RM, McLean CA, Laughton KM, Beyreuther K, Evin G, Masters CL, Li QX. APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease. Neurobiology of Disease. 16: 124-32. PMID 15207269 DOI: 10.1016/J.Nbd.2004.01.009 |
0.533 |
|
| 2004 |
Loewer A, Soba P, Beyreuther K, Paro R, Merdes G. Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development. Embo Reports. 5: 405-11. PMID 15105831 DOI: 10.1038/Sj.Embor.7400122 |
0.821 |
|
| 2004 |
Zha Q, Ruan Y, Hartmann T, Beyreuther K, Zhang D. GM1 ganglioside regulates the proteolysis of amyloid precursor protein. Molecular Psychiatry. 9: 946-52. PMID 15052275 DOI: 10.1038/Sj.Mp.4001509 |
0.558 |
|
| 2004 |
Eggert S, Paliga K, Soba P, Evin G, Masters CL, Weidemann A, Beyreuther K. The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation. The Journal of Biological Chemistry. 279: 18146-56. PMID 14970212 DOI: 10.1074/Jbc.M311601200 |
0.832 |
|
| 2004 |
White AR, Barnham KJ, Huang X, Voltakis I, Beyreuther K, Masters CL, Cherny RA, Bush AI, Cappai R. Iron inhibits neurotoxicity induced by trace copper and biological reductants. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 9: 269-80. PMID 14758525 DOI: 10.1007/S00775-004-0521-8 |
0.488 |
|
| 2004 |
Fassbender K, Walter S, Kühl S, Landmann R, Ishii K, Bertsch T, Stalder AK, Muehlhauser F, Liu Y, Ulmer AJ, Rivest S, Lentschat A, Gulbins E, Jucker M, Staufenbiel M, ... ... Beyreuther K, et al. The LPS receptor (CD14) links innate immunity with Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 203-5. PMID 14597556 DOI: 10.1096/Fj.03-0364Fje |
0.368 |
|
| 2004 |
Loewer A, Soba P, Bilic MV, Kuttenkeuler D, Beyreuther K, Paro R, Merdes G. P2-114 Cell-type specific processing of the APP protein family in drosophila Neurobiology of Aging. 25: S257. DOI: 10.1016/S0197-4580(04)80861-3 |
0.79 |
|
| 2004 |
Cappai R, Kong G, McKinstry W, Galatis D, Adams J, Bellingham S, Camakaris J, Curtain C, Williamson N, White A, Beyreuther K, Multhaup G, Masters C, Barnham K, Parker M. O3-04-06 Structural and functional analysis of the Alzheimer's disease amyloid precursor protein copper binding domain Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80203-3 |
0.542 |
|
| 2004 |
Maruff PT, Li Q, Shafiq-Antonacci R, Weaver-Cargin J, Laughton KM, Mastywk M, Beyreuther K, Masters C. O2-02-03 Change in plasma amyloid concentration is associated with memory decline in MCI Neurobiology of Aging. 25: S34. DOI: 10.1016/S0197-4580(04)80113-1 |
0.399 |
|
| 2003 |
Ritchie CW, Bush AI, Mackinnon A, Macfarlane S, Mastwyk M, MacGregor L, Kiers L, Cherny R, Li QX, Tammer A, Carrington D, Mavros C, Volitakis I, Xilinas M, Ames D, ... ... Beyreuther K, et al. Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Archives of Neurology. 60: 1685-91. PMID 14676042 DOI: 10.1001/Archneur.60.12.1685 |
0.547 |
|
| 2003 |
Schmechel A, Zentgraf H, Scheuermann S, Fritz G, Pipkorn R, Reed J, Beyreuther K, Bayer TA, Multhaup G. Alzheimer beta-amyloid homodimers facilitate A beta fibrillization and the generation of conformational antibodies. The Journal of Biological Chemistry. 278: 35317-24. PMID 12840025 DOI: 10.1074/Jbc.M303547200 |
0.422 |
|
| 2003 |
Rutten BP, Wirths O, Van de Berg WD, Lichtenthaler SF, Vehoff J, Steinbusch HW, Korr H, Beyreuther K, Multhaup G, Bayer TA, Schmitz C. No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the beta-cleaved C-terminal APP fragment. Neurobiology of Disease. 12: 110-20. PMID 12667466 DOI: 10.1016/S0969-9961(02)00015-3 |
0.458 |
|
| 2003 |
White AR, Maher F, Brazier MW, Jobling MF, Thyer J, Stewart LR, Thompson A, Gibson R, Masters CL, Multhaup G, Beyreuther K, Barrow CJ, Collins SJ, Cappai R. Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation. Brain Research. 966: 231-44. PMID 12618346 DOI: 10.1016/S0006-8993(02)04173-2 |
0.574 |
|
| 2003 |
Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS, Beyreuther K, Masters CL, Parker MW, Cappai R. Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis. The Journal of Biological Chemistry. 278: 17401-7. PMID 12611883 DOI: 10.1074/jbc.M300629200 |
0.457 |
|
| 2003 |
Gamliel A, Teicher C, Hartmann T, Beyreuther K, Stein R. Overexpression of wild-type presenilin 2 or its familial Alzheimer's disease-associated mutant does not induce or increase susceptibility to apoptosis in different cell lines. Neuroscience. 117: 19-28. PMID 12605888 DOI: 10.1016/S0306-4522(02)00830-8 |
0.337 |
|
| 2003 |
Grimm HS, Beher D, Lichtenthaler SF, Shearman MS, Beyreuther K, Hartmann T. gamma-Secretase cleavage site specificity differs for intracellular and secretory amyloid beta. The Journal of Biological Chemistry. 278: 13077-85. PMID 12556458 DOI: 10.1074/jbc.M210380200 |
0.315 |
|
| 2003 |
Sernee MF, Evin G, Culvenor JG, Villadangos JA, Beyreuther K, Masters CL, Cappai R. Selecting cells with different Alzheimer's disease gamma-secretase activity using FACS. Differential effect on presenilin exon 9 gamma- and epsilon-cleavage. European Journal of Biochemistry / Febs. 270: 495-506. PMID 12542699 DOI: 10.1046/J.1432-1033.2003.03405.X |
0.509 |
|
| 2003 |
Grziwa B, Grimm MO, Masters CL, Beyreuther K, Hartmann T, Lichtenthaler SF. The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted. The Journal of Biological Chemistry. 278: 6803-8. PMID 12454010 DOI: 10.1074/jbc.M210047200 |
0.386 |
|
| 2002 |
Khalil Z, Poliviou H, Maynard CJ, Beyreuther K, Masters CL, Li QX. Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein. Journal of Alzheimer's Disease : Jad. 4: 467-78. PMID 12515898 DOI: 10.3233/Jad-2002-4603 |
0.519 |
|
| 2002 |
Li QX, Campbell BC, McLean CA, Thyagarajan D, Gai WP, Kapsa RM, Beyreuther K, Masters CL, Culvenor JG. Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects. Journal of Alzheimer's Disease : Jad. 4: 309-15. PMID 12446933 DOI: 10.3233/Jad-2002-4406 |
0.407 |
|
| 2002 |
Maynard CJ, Cappai R, Volitakis I, Cherny RA, White AR, Beyreuther K, Masters CL, Bush AI, Li QX. Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron. The Journal of Biological Chemistry. 277: 44670-6. PMID 12215434 DOI: 10.1074/Jbc.M204379200 |
0.583 |
|
| 2002 |
Simons M, Schwärzler F, Lütjohann D, von Bergmann K, Beyreuther K, Dichgans J, Wormstall H, Hartmann T, Schulz JB. Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial. Annals of Neurology. 52: 346-50. PMID 12205648 DOI: 10.1002/Ana.10292 |
0.648 |
|
| 2002 |
Wirths O, Multhaup G, Czech C, Feldmann N, Blanchard V, Tremp G, Beyreuther K, Pradier L, Bayer TA. Intraneuronal APP/A beta trafficking and plaque formation in beta-amyloid precursor protein and presenilin-1 transgenic mice. Brain Pathology (Zurich, Switzerland). 12: 275-86. PMID 12146796 DOI: 10.1111/J.1750-3639.2002.Tb00442.X |
0.441 |
|
| 2002 |
Simons A, Ruppert T, Schmidt C, Schlicksupp A, Pipkorn R, Reed J, Masters CL, White AR, Cappai R, Beyreuther K, Bayer TA, Multhaup G. Evidence for a copper-binding superfamily of the amyloid precursor protein. Biochemistry. 41: 9310-20. PMID 12135352 DOI: 10.1021/Bi0258647 |
0.326 |
|
| 2002 |
Holsinger RM, McLean CA, Beyreuther K, Masters CL, Evin G. Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease. Annals of Neurology. 51: 783-6. PMID 12112088 DOI: 10.1002/Ana.10208 |
0.615 |
|
| 2002 |
Mok SS, Turner BJ, Beyreuther K, Masters CL, Barrow CJ, Small DH. Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine. European Journal of Biochemistry / Febs. 269: 3014-22. PMID 12071966 DOI: 10.1046/J.1432-1033.2002.02976.X |
0.573 |
|
| 2002 |
Fodero LR, Sáez-Valero J, McLean CA, Martins RN, Beyreuther K, Masters CL, Robertson TA, Small DH. Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition. Journal of Neurochemistry. 81: 441-8. PMID 12065653 DOI: 10.1046/J.1471-4159.2002.00902.X |
0.505 |
|
| 2002 |
Hamilton JA, Whitty G, White AR, Jobling MF, Thompson A, Barrow CJ, Cappai R, Beyreuther K, Masters CL. Alzheimer's disease amyloid beta and prion protein amyloidogenic peptides promote macrophage survival, DNA synthesis and enhanced proliferative response to CSF-1 (M-CSF). Brain Research. 940: 49-54. PMID 12020874 DOI: 10.1016/S0006-8993(02)02589-1 |
0.488 |
|
| 2002 |
Evin G, Smith MJ, Tziotis A, McLean C, Canterford L, Sharples RA, Cappai R, Weidemann A, Beyreuther K, Cotton RG, Masters CL, Culvenor JG. Alternative transcripts of presenilin-1 associated with frontotemporal dementia. Neuroreport. 13: 917-21. PMID 11997713 |
0.396 |
|
| 2002 |
Evin G, Smith MJ, Tziotis A, McLean C, Canterford L, Sharples RA, Cappai R, Weidemann A, Beyreuther K, Cotton RG, Masters CL, Culvenor JG. Alternative transcripts of presenilin-1 associated with frontotemporal dementia. Neuroreport. 13: 719-23. PMID 11973477 DOI: 10.1097/00001756-200204160-00036 |
0.396 |
|
| 2002 |
Runz H, Rietdorf J, Tomic I, de Bernard M, Beyreuther K, Pepperkok R, Hartmann T. Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1679-89. PMID 11880497 DOI: 10.1523/Jneurosci.22-05-01679.2002 |
0.475 |
|
| 2002 |
Weidemann A, Eggert S, Reinhard FB, Vogel M, Paliga K, Baier G, Masters CL, Beyreuther K, Evin G. A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing. Biochemistry. 41: 2825-35. PMID 11851430 DOI: 10.1021/Bi015794O |
0.799 |
|
| 2002 |
Gamliel A, Teicher C, Michaelson DM, Pradier L, Hartmann T, Beyreuther K, Stein R. Increased expression of presenilin 2 inhibits protein synthesis. Molecular and Cellular Neurosciences. 19: 111-24. PMID 11817902 DOI: 10.1006/mcne.2001.1068 |
0.304 |
|
| 2002 |
Lichtenthaler SF, Beher D, Grimm HS, Wang R, Shearman MS, Masters CL, Beyreuther K. The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain. Proceedings of the National Academy of Sciences of the United States of America. 99: 1365-70. PMID 11805291 DOI: 10.1073/Pnas.032395699 |
0.487 |
|
| 2002 |
White AR, Multhaup G, Galatis D, McKinstry WJ, Parker MW, Pipkorn R, Beyreuther K, Masters CL, Cappai R. Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 365-76. PMID 11784781 DOI: 10.1523/Jneurosci.22-02-00365.2002 |
0.456 |
|
| 2001 |
Masters CL, Beyreuther K. Henryk M. Wisniewski and the amyloid theory of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 3: 83-86. PMID 12214076 DOI: 10.3233/Jad-2001-3112 |
0.553 |
|
| 2001 |
McLean CA, Beyreuther K, Masters CL. Amyloid Abeta levels in Alzheimer's disease - A diagnostic tool and the key to understanding the natural history of Abeta? Journal of Alzheimer's Disease : Jad. 3: 305-312. PMID 12214051 DOI: 10.3233/Jad-2001-3305 |
0.591 |
|
| 2001 |
Wirths O, Multhaup G, Czech C, Blanchard V, Tremp G, Pradier L, Beyreuther K, Bayer TA. Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice. Neuroscience Letters. 316: 145-8. PMID 11744223 DOI: 10.1016/S0304-3940(01)02399-0 |
0.523 |
|
| 2001 |
Nunan J, Shearman MS, Checler F, Cappai R, Evin G, Beyreuther K, Masters CL, Small DH. The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase. European Journal of Biochemistry / Febs. 268: 5329-36. PMID 11606195 DOI: 10.1046/J.0014-2956.2001.02465.X |
0.622 |
|
| 2001 |
Stewart LR, White AR, Jobling MF, Needham BE, Maher F, Thyer J, Beyreuther K, Masters CL, Collins SJ, Cappai R. Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126. Journal of Neuroscience Research. 65: 565-72. PMID 11550224 DOI: 10.1002/jnr.1186 |
0.358 |
|
| 2001 |
Fassbender K, Masters C, Beyreuther K. Alzheimer's disease: molecular concepts and therapeutic targets. Die Naturwissenschaften. 88: 261-7. PMID 11544953 DOI: 10.1007/s001140100237 |
0.404 |
|
| 2001 |
Evin G, Sharples RA, Weidemann A, Reinhard FB, Carbone V, Culvenor JG, Holsinger RM, Sernee MF, Beyreuther K, Masters CL. Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease. Biochemistry. 40: 8359-68. PMID 11444983 DOI: 10.1021/bi002770t |
0.475 |
|
| 2001 |
Scheuermann S, Hambsch B, Hesse L, Stumm J, Schmidt C, Beher D, Bayer TA, Beyreuther K, Multhaup G. Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease. The Journal of Biological Chemistry. 276: 33923-9. PMID 11438549 DOI: 10.1074/jbc.M105410200 |
0.442 |
|
| 2001 |
Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser FW, Kim Y, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, et al. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron. 30: 665-76. PMID 11430801 DOI: 10.1016/S0896-6273(01)00317-8 |
0.564 |
|
| 2001 |
Jayasena UL, Gribble SK, McKenzie A, Beyreuther K, Masters CL, Underwood JR. Identification of structural variations in the carboxyl terminus of Alzheimer's disease-associated beta A4[1-42] amyloid using a monoclonal antibody. Clinical and Experimental Immunology. 124: 297-305. PMID 11422208 DOI: 10.1046/J.1365-2249.2001.01209.X |
0.502 |
|
| 2001 |
Wirths O, Multhaup G, Czech C, Blanchard V, Moussaoui S, Tremp G, Pradier L, Beyreuther K, Bayer TA. Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice. Neuroscience Letters. 306: 116-20. PMID 11403971 DOI: 10.1016/S0304-3940(01)01876-6 |
0.541 |
|
| 2001 |
White AR, Guirguis R, Brazier MW, Jobling MF, Hill AF, Beyreuther K, Barrow CJ, Masters CL, Collins SJ, Cappai R. Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons. Neurobiology of Disease. 8: 299-316. PMID 11300725 DOI: 10.1006/nbdi.2001.0386 |
0.339 |
|
| 2001 |
Fassbender K, Simons M, Bergmann C, Stroick M, Lutjohann D, Keller P, Runz H, Kuhl S, Bertsch T, von Bergmann K, Hennerici M, Beyreuther K, Hartmann T. Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 98: 5856-61. PMID 11296263 DOI: 10.1073/Pnas.081620098 |
0.503 |
|
| 2001 |
Curtain CC, Ali F, Volitakis I, Cherny RA, Norton RS, Beyreuther K, Barrow CJ, Masters CL, Bush AI, Barnham KJ. Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits. The Journal of Biological Chemistry. 276: 20466-73. PMID 11274207 DOI: 10.1074/Jbc.M100175200 |
0.567 |
|
| 2001 |
White AR, Huang X, Jobling MF, Barrow CJ, Beyreuther K, Masters CL, Bush AI, Cappai R. Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways. Journal of Neurochemistry. 76: 1509-20. PMID 11238735 DOI: 10.1046/J.1471-4159.2001.00178.X |
0.453 |
|
| 2001 |
Campbell BC, McLean CA, Culvenor JG, Gai WP, Blumbergs PC, Jäkälä P, Beyreuther K, Masters CL, Li QX. The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease. Journal of Neurochemistry. 76: 87-96. PMID 11145981 DOI: 10.1046/J.1471-4159.2001.00021.X |
0.401 |
|
| 2001 |
Bayer TA, Wirths O, Majtényi K, Hartmann T, Multhaup G, Beyreuther K, Czech C. Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport. Brain Pathology (Zurich, Switzerland). 11: 1-11. PMID 11145195 DOI: 10.1111/J.1750-3639.2001.Tb00376.X |
0.55 |
|
| 2001 |
McLean CA, Beyreuther K, Masters CL. Amyloid Aβ levels in Alzheimer's disease - A diagnostic tool and the key to understanding the natural history of Aβ? Journal of Alzheimer's Disease. 3: 305-312. |
0.508 |
|
| 2000 |
Weidemann A, Paliga K, Dürrwang U, Reinhard F, Zhang D, Sandbrink R, Evin G, Masters CL, Beyreuther K. Interaction of the Presenilins with the Amyloid Precursor Protein (APP). Methods in Molecular Medicine. 32: 333-44. PMID 21318530 DOI: 10.1385/1-59259-195-7:333 |
0.57 |
|
| 2000 |
Wirths O, Weickert S, Majtenyi K, Havas L, Kahle PJ, Okochi M, Haass C, Multhaup G, Beyreuther K, Bayer TA. Lewy body variant of Alzheimer's disease: alpha-synuclein in dystrophic neurites of A beta plaques. Neuroreport. 11: 3737-41. PMID 11117482 DOI: 10.1097/00001756-200011270-00029 |
0.462 |
|
| 2000 |
Schonknecht P, Pantel J, Werle E, Hartmann T, Essig M, Baudendistel K, Beyreuther K, Schroder J. [Cerebrospinal fluid protein tau levels in the differential diagnosis of Alzheimer's disease]. Fortschritte Der Neurologie-Psychiatrie. 68: 439-46. PMID 11103680 DOI: 10.1016/S0197-4580(00)82805-5 |
0.379 |
|
| 2000 |
Jensen M, Hartmann T, Engvall B, Wang R, Uljon SN, Sennvik K, Näslund J, Muehlhauser F, Nordstedt C, Beyreuther K, Lannfelt L. Quantification of Alzheimer amyloid beta peptides ending at residues 40 and 42 by novel ELISA systems. Molecular Medicine (Cambridge, Mass.). 6: 291-302. PMID 10949910 DOI: 10.1007/Bf03401938 |
0.453 |
|
| 2000 |
Cherny RA, Barnham KJ, Lynch T, Volitakis I, Li QX, McLean CA, Multhaup G, Beyreuther K, Tanzi RE, Masters CL, Bush AI. Chelation and intercalation: complementary properties in a compound for the treatment of Alzheimer's disease. Journal of Structural Biology. 130: 209-16. PMID 10940226 DOI: 10.1006/Jsbi.2000.4285 |
0.557 |
|
| 2000 |
Mok SS, Clippingdale AB, Beyreuther K, Masters CL, Barrow CJ, Small DH. A beta peptides and calcium influence secretion of the amyloid protein precursor from chick sympathetic neurons in culture. Journal of Neuroscience Research. 61: 449-57. PMID 10931532 DOI: 10.1002/1097-4547(20000815)61:4<449::Aid-Jnr12>3.0.Co;2-N |
0.55 |
|
| 2000 |
Ishii K, Muelhauser F, Liebl U, Picard M, Kühl S, Penke B, Bayer T, Wiessler M, Hennerici M, Beyreuther K, Hartmann T, Fassbender K. Subacute NO generation induced by Alzheimer's beta-amyloid in the living brain: reversal by inhibition of the inducible NO synthase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 1485-9. PMID 10928982 |
0.411 |
|
| 2000 |
Borchardt T, Schmidt C, Camarkis J, Cappai R, Masters CL, Beyreuther K, Multhaup G. Differential effects of zinc on amyloid precursor protein (APP) processing in copper-resistant variants of cultured Chinese hamster ovary cells. Cellular and Molecular Biology (Noisy-Le-Grand, France). 46: 785-95. PMID 10875440 |
0.309 |
|
| 2000 |
Campbell BC, Li QX, Culvenor JG, Jäkälä P, Cappai R, Beyreuther K, Masters CL, McLean CA. Accumulation of insoluble alpha-synuclein in dementia with Lewy bodies. Neurobiology of Disease. 7: 192-200. PMID 10860784 DOI: 10.1006/Nbdi.2000.0286 |
0.495 |
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| 2000 |
Fassbender K, Masters C, Beyreuther K. Alzheimer's disease: an inflammatory disease? Neurobiology of Aging. 21: 433-6; discussion 45. PMID 10858589 DOI: 10.1016/S0197-4580(00)00147-0 |
0.483 |
|
| 2000 |
Smith MJ, Humphrey KE, Cappai R, Beyreuther K, Masters CL, Cotton RG. Correct heteroduplex formation for mutation detection analysis. Molecular Diagnosis : a Journal Devoted to the Understanding of Human Disease Through the Clinical Application of Molecular Biology. 5: 67-73. PMID 10837092 DOI: 10.1007/Bf03262025 |
0.381 |
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| 2000 |
Emilien G, Beyreuther K, Masters CL, Maloteaux JM. Prospects for pharmacological intervention in Alzheimer disease. Archives of Neurology. 57: 454-9. PMID 10768617 DOI: 10.1001/Archneur.57.4.454 |
0.562 |
|
| 2000 |
Culvenor JG, Evin G, Cooney MA, Wardan H, Sharples RA, Maher F, Reed G, Diehlmann A, Weidemann A, Beyreuther K, Masters CL. Presenilin 2 expression in neuronal cells: induction during differentiation of embryonic carcinoma cells. Experimental Cell Research. 255: 192-206. PMID 10694435 DOI: 10.1006/Excr.1999.4791 |
0.501 |
|
| 2000 |
Postuma RB, He W, Nunan J, Beyreuther K, Masters CL, Barrow CJ, Small DH. Substrate-bound beta-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures. Journal of Neurochemistry. 74: 1122-30. PMID 10693944 DOI: 10.1046/J.1471-4159.2000.741122.X |
0.582 |
|
| 2000 |
Emilien G, Maloteaux JM, Beyreuther K, Masters CL. Alzheimer disease: mouse models pave the way for therapeutic opportunities. Archives of Neurology. 57: 176-81. PMID 10681074 DOI: 10.1001/Archneur.57.2.176 |
0.606 |
|
| 2000 |
Coulson EJ, Paliga K, Beyreuther K, Masters CL. What the evolution of the amyloid protein precursor supergene family tells us about its function. Neurochemistry International. 36: 175-84. PMID 10676850 DOI: 10.1016/S0197-0186(99)00125-4 |
0.534 |
|
| 2000 |
Evin G, Le Brocque D, Culvenor JG, Galatis D, Weidemann A, Beyreuther K, Masters CL, Cappai R. Presenilin I expression in yeast lowers secretion of the amyloid precursor protein. Neuroreport. 11: 405-8. PMID 10674495 DOI: 10.1097/00001756-200002070-00036 |
0.583 |
|
| 2000 |
Hashimoto M, Takenouchi T, Mallory M, Masliah E, Culvenor JG, McLean CA, Campbell BCV, Masters CL, Li QX, Jakala P, Hartmann T, Beyreuther K. The role of NAC in amyloidogenesis in Alzheimer's disease [2] (multiple letters) American Journal of Pathology. 156: 734-736. PMID 10667911 DOI: 10.1016/S0002-9440(10)64777-3 |
0.515 |
|
| 2000 |
Kwok JB, Li QX, Hallupp M, Whyte S, Ames D, Beyreuther K, Masters CL, Schofield PR. Novel Leu723Pro amyloid precursor protein mutation increases amyloid beta42(43) peptide levels and induces apoptosis. Annals of Neurology. 47: 249-53. PMID 10665499 DOI: 10.1002/1531-8249(200002)47:2<249::Aid-Ana18>3.0.Co;2-8 |
0.589 |
|
| 2000 |
Bergsdorf C, Paliga K, Kreger S, Masters CL, Beyreuther K. Identification of cis-elements regulating exon 15 splicing of the amyloid precursor protein pre-mRNA. The Journal of Biological Chemistry. 275: 2046-56. PMID 10636908 DOI: 10.1074/Jbc.275.3.2046 |
0.563 |
|
| 2000 |
Ishii K, Muelhauser F, Liebl U, Picard M, Kühl S, Penke B, Bayer T, Wiessler M, Hennerici M, Beyreuther K, Hartmann T, Fassbender K. Subacute NO generation induced by Alzheimer’s β-amyloid in the living brain: reversal by inhibition of the inducible NO synthase The Faseb Journal. 14: 1485-1489. DOI: 10.1096/Fj.99-0786Com |
0.451 |
|
| 2000 |
Rossiohn J, Cappai R, Feil SC, Henry A, McKinstry WJ, Galatis D, Hesse L, Multhaup G, Beyreuther K, Masters CL, Parker MW. Crystal Structure of the N-terminal Heparin-Binding Domain of Alzheimer's Amyloid Precursor Protein Biochemical Society Transactions. 28: A447-A447. DOI: 10.1042/Bst028A447 |
0.519 |
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| 2000 |
Hesse L, Ruppert T, Malcherek S, Cappai R, Masters C, Beyreuther K, Multhaup G. THE CYSTEINE-RICH DOMAIN OF THE AMYLOID PRECURSOR PROTEIN (APP) CONTAINS SIX DISULPHIDE BRIDGES IN TWO SUBDOMAINS Biochemical Society Transactions. 28: A87-A87. DOI: 10.1042/Bst028A087 |
0.548 |
|
| 2000 |
Masters CL, Beyreuther K. Pathogenic mechanisms underlying biogenesis of a β from amyloid precursor protein Neurobiology of Aging. 21: 5. DOI: 10.1016/S0197-4580(00)82697-4 |
0.487 |
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| 2000 |
Beyreuther K, Masters CL. Physiological function of APP processing Neurobiology of Aging. 21: 69. DOI: 10.1016/S0197-4580(00)82532-4 |
0.434 |
|
| 2000 |
Schroeder J, Pantel J, Klinga K, Jensen M, Schoenknecht P, Beyreuther K, Hartmann T. Reduced cerebrospinal fluid estradiol levels are associated with early onset and increased β-amyloid levels in Alzheimers disease Neurobiology of Aging. 21: 61. DOI: 10.1016/S0197-4580(00)82498-7 |
0.377 |
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| 2000 |
Zhang D, Zhang H, Tian W, Hartmann T, Beyreuther K. Relationships between ganglioside GM1 and the transcription of APP gene and the metabolism of APP Neurobiology of Aging. 21: 190. DOI: 10.1016/S0197-4580(00)82196-X |
0.311 |
|
| 2000 |
Lichtenthaler SF, Masters CL, Beyreuther K. Proteolytic Processing of the Amyloid Precursor Protein of Alzheimer’s Disease Handbook of Experimental Pharmacology. 140: 359-374. DOI: 10.1007/978-3-642-57092-6_19 |
0.594 |
|
| 1999 |
Small DH, Clarris HL, Williamson TG, Reed G, Key B, Mok SS, Beyreuther K, Masters CL, Nurcombe V. Neurite-outgrowth regulating functions of the amyloid protein precursor of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 1: 275-85. PMID 12214125 DOI: 10.3233/Jad-1999-14-508 |
0.623 |
|
| 1999 |
Yang Y, Beyreuther K, Schmitt HP. Spatial analysis of the neuronal density of aminergic brainstem nuclei in primary neurodegenerative and vascular dementia: a comparative immunocytochemical and quantitative study using a graph method. Analytical Cellular Pathology : the Journal of the European Society For Analytical Cellular Pathology. 19: 125-38. PMID 10866275 DOI: 10.1155/1999/256382 |
0.389 |
|
| 1999 |
McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, Bush AI, Masters CL. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Annals of Neurology. 46: 860-6. PMID 10589538 DOI: 10.1002/1531-8249(199912)46:6<860::Aid-Ana8>3.0.Co;2-M |
0.536 |
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| 1999 |
Bayer TA, Cappai R, Masters CL, Beyreuther K, Multhaup G. It all sticks together--the APP-related family of proteins and Alzheimer's disease. Molecular Psychiatry. 4: 524-8. PMID 10578233 DOI: 10.1038/Sj.Mp.4000552 |
0.576 |
|
| 1999 |
Borchardt T, Camakaris J, Cappai R, Masters CL, Beyreuther K, Multhaup G. Copper inhibits beta-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion. The Biochemical Journal. 344: 461-7. PMID 10567229 DOI: 10.1042/Bj3440461 |
0.567 |
|
| 1999 |
Caswell MD, Mok SS, Henry A, Cappai R, Klug G, Beyreuther K, Masters CL, Small DH. The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons. European Journal of Biochemistry / Febs. 266: 509-16. PMID 10561592 DOI: 10.1046/J.1432-1327.1999.00886.X |
0.61 |
|
| 1999 |
White AR, Collins SJ, Maher F, Jobling MF, Stewart LR, Thyer JM, Beyreuther K, Masters CL, Cappai R. Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity. The American Journal of Pathology. 155: 1723-30. PMID 10550328 DOI: 10.1016/S0002-9440(10)65487-9 |
0.42 |
|
| 1999 |
Li QX, Fuller SJ, Beyreuther K, Masters CL. The amyloid precursor protein of Alzheimer disease in human brain and blood. Journal of Leukocyte Biology. 66: 567-74. PMID 10534110 DOI: 10.1002/Jlb.66.4.567 |
0.596 |
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| 1999 |
White AR, Multhaup G, Maher F, Bellingham S, Camakaris J, Zheng H, Bush AI, Beyreuther K, Masters CL, Cappai R. The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9170-9. PMID 10531420 DOI: 10.1523/Jneurosci.19-21-09170.1999 |
0.495 |
|
| 1999 |
White AR, Reyes R, Mercer JF, Camakaris J, Zheng H, Bush AI, Multhaup G, Beyreuther K, Masters CL, Cappai R. Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice. Brain Research. 842: 439-44. PMID 10526140 DOI: 10.1016/S0006-8993(99)01861-2 |
0.561 |
|
| 1999 |
Culvenor JG, McLean CA, Cutt S, Campbell BC, Maher F, Jäkälä P, Hartmann T, Beyreuther K, Masters CL, Li QX. Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid. The American Journal of Pathology. 155: 1173-81. PMID 10514400 DOI: 10.1016/S0002-9440(10)65220-0 |
0.589 |
|
| 1999 |
Bayer TA, Jäkälä P, Hartmann T, Egensperger R, Buslei R, Falkai P, Beyreuther K. Neural expression profile of alpha-synuclein in developing human cortex. Neuroreport. 10: 2799-803. PMID 10511443 DOI: 10.1097/00001756-199909090-00019 |
0.325 |
|
| 1999 |
Jobling MF, Stewart LR, White AR, McLean C, Friedhuber A, Maher F, Beyreuther K, Masters CL, Barrow CJ, Collins SJ, Cappai R. The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126. Journal of Neurochemistry. 73: 1557-65. PMID 10501201 DOI: 10.1046/J.1471-4159.1999.0731557.X |
0.489 |
|
| 1999 |
Bayer TA, Jäkälä P, Hartmann T, Havas L, McLean C, Culvenor JG, Li QX, Masters CL, Falkai P, Beyreuther K. Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores. Neuroscience Letters. 266: 213-6. PMID 10465711 DOI: 10.1016/S0304-3940(99)00311-0 |
0.556 |
|
| 1999 |
Masters CL, Beyreuther K. Amyloid Nomenclature Committee. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 6: 151-2. PMID 10439124 DOI: 10.3109/13506129909007318 |
0.575 |
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| 1999 |
Cherny RA, Legg JT, McLean CA, Fairlie DP, Huang X, Atwood CS, Beyreuther K, Tanzi RE, Masters CL, Bush AI. Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion. The Journal of Biological Chemistry. 274: 23223-8. PMID 10438495 DOI: 10.1074/Jbc.274.33.23223 |
0.552 |
|
| 1999 |
Lichtenthaler SF, Multhaup G, Masters CL, Beyreuther K. A novel substrate for analyzing Alzheimer's disease gamma-secretase. Febs Letters. 453: 288-92. PMID 10405162 DOI: 10.1016/S0014-5793(99)00730-9 |
0.618 |
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| 1999 |
Christie G, Markwell RE, Gray CW, Smith L, Godfrey F, Mansfield F, Wadsworth H, King R, McLaughlin M, Cooper DG, Ward RV, Howlett DR, Hartmann T, Lichtenthaler SF, Beyreuther K, et al. Alzheimer's disease: correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome. Journal of Neurochemistry. 73: 195-204. PMID 10386971 DOI: 10.1046/J.1471-4159.1999.0730195.X |
0.511 |
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| 1999 |
Li QX, Maynard C, Cappai R, McLean CA, Cherny RA, Lynch T, Culvenor JG, Trevaskis J, Tanner JE, Bailey KA, Czech C, Bush AI, Beyreuther K, Masters CL. Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice. Journal of Neurochemistry. 72: 2479-87. PMID 10349858 DOI: 10.1046/J.1471-4159.1999.0722479.X |
0.529 |
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| 1999 |
Diehlmann A, Ida N, Weggen S, Grünberg J, Haass C, Masters CL, Bayer TA, Beyreuther K. Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies. Journal of Neuroscience Research. 56: 405-19. PMID 10340748 DOI: 10.1002/(Sici)1097-4547(19990515)56:4<405::Aid-Jnr8>3.0.Co;2-F |
0.568 |
|
| 1999 |
White AR, Bush AI, Beyreuther K, Masters CL, Cappai R. Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione. Journal of Neurochemistry. 72: 2092-8. PMID 10217289 DOI: 10.1046/J.1471-4159.1999.0722092.X |
0.478 |
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| 1999 |
Storey E, Katz M, Brickman Y, Beyreuther K, Masters CL. Amyloid precursor protein of Alzheimer's disease: evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures. The European Journal of Neuroscience. 11: 1779-88. PMID 10215930 DOI: 10.1046/J.1460-9568.1999.00599.X |
0.405 |
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| 1999 |
Jensen M, Schröder J, Blomberg M, Engvall B, Pantel J, Ida N, Basun H, Wahlund LO, Werle E, Jauss M, Beyreuther K, Lannfelt L, Hartmann T. Cerebrospinal fluid A beta42 is increased early in sporadic Alzheimer's disease and declines with disease progression. Annals of Neurology. 45: 504-11. PMID 10211475 DOI: 10.1002/1531-8249(199904)45:4<504::Aid-Ana12>3.0.Co;2-9 |
0.422 |
|
| 1999 |
Smith MJ, Gardner RJ, Knight MA, Forrest SM, Beyreuther K, Storey E, McLean CA, Cotton RG, Cappal R, Masters CL. Early-onset Alzheimer's disease caused by a novel mutation at codon 219 of the presenilin-1 gene. Neuroreport. 10: 503-7. PMID 10208579 DOI: 10.1097/00001756-199902250-00011 |
0.435 |
|
| 1999 |
Rossjohn J, Cappai R, Feil SC, Henry A, McKinstry WJ, Galatis D, Hesse L, Multhaup G, Beyreuther K, Masters CL, Parker MW. Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nature Structural Biology. 6: 327-31. PMID 10201399 DOI: 10.1038/7562 |
0.555 |
|
| 1999 |
Beher D, Elle C, Underwood J, Davis JB, Ward R, Karran E, Masters CL, Beyreuther K, Multhaup G. Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain. Journal of Neurochemistry. 72: 1564-73. PMID 10098862 DOI: 10.1046/J.1471-4159.1999.721564.X |
0.515 |
|
| 1999 |
Connop BP, Thies RL, Beyreuther K, Ida N, Reiner PB. Novel effects of FCCP [carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone] on amyloid precursor protein processing. Journal of Neurochemistry. 72: 1457-65. PMID 10098849 DOI: 10.1046/J.1471-4159.1999.721457.X |
0.482 |
|
| 1999 |
Multhaup G, Hesse L, Borchardt T, Ruppert T, Cappai R, Masters CL, Beyreuther K. Autoxidation of amyloid precursor protein and formation of reactive oxygen species. Advances in Experimental Medicine and Biology. 448: 183-92. PMID 10079826 DOI: 10.1007/978-1-4615-4859-1_16 |
0.597 |
|
| 1999 |
Cappai R, Stewart L, Jobling MF, Thyer JM, White AR, Beyreuther K, Collins SJ, Masters CL, Barrow CJ. Familial prion disease mutation alters the secondary structure of recombinant mouse prion protein: implications for the mechanism of prion formation. Biochemistry. 38: 3280-4. PMID 10079070 DOI: 10.1021/Bi982328Z |
0.48 |
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| 1999 |
Lichtenthaler SF, Wang R, Grimm H, Uljon SN, Masters CL, Beyreuther K. Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 3053-8. PMID 10077635 DOI: 10.1073/Pnas.96.6.3053 |
0.589 |
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| 1999 |
Egensperger R, Weggen S, Ida N, Multhaup G, Schnabel R, Beyreuther K, Bayer TA. Reverse relationship between beta-amyloid precursor protein and beta-amyloid peptide plaques in Down's syndrome versus sporadic/familial Alzheimer's disease. Acta Neuropathologica. 97: 113-8. PMID 9928821 DOI: 10.1007/S004010050963 |
0.528 |
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| 1999 |
Cappai R, Mok SS, Galatis D, Tucker DF, Henry A, Beyreuther K, Small DH, Masters CL. Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth. Febs Letters. 442: 95-8. PMID 9923612 DOI: 10.1016/S0014-5793(98)01635-4 |
0.59 |
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| 1999 |
Hartmann T, Simons M, Jensen M, Lichtenthaler S, Bergmann C, Jäkälä P, Grimm H, Zhang D, Beyreuther K. Central amyloidosis in Alzheimer's disease: Biology of the production of the amyloid peptide European Neuropsychopharmacology. 9: 140-141. DOI: 10.1016/S0924-977X(99)80014-5 |
0.451 |
|
| 1998 |
Zhang D, Ruan Y, Beyreuther K. [Effect of ganglioside GM1 on the metabolism of Alzheimer amyloid beta-protein precursor]. Zhonghua Yi Xue Za Zhi. 78: 179-82. PMID 10923524 |
0.401 |
|
| 1998 |
Weggen S, Diehlmann A, Buslei R, Beyreuther K, Bayer TA. Prominent expression of presenilin-1 in senile plaques and reactive astrocytes in Alzheimer's disease brain. Neuroreport. 9: 3279-83. PMID 9831464 |
0.368 |
|
| 1998 |
Henry A, Li QX, Galatis D, Hesse L, Multhaup G, Beyreuther K, Masters CL, Cappai R. Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein. British Journal of Haematology. 103: 402-15. PMID 9827912 DOI: 10.1046/J.1365-2141.1998.01005.X |
0.481 |
|
| 1998 |
Fossgreen A, Brückner B, Czech C, Masters CL, Beyreuther K, Paro R. Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype. Proceedings of the National Academy of Sciences of the United States of America. 95: 13703-8. PMID 9811864 DOI: 10.1073/Pnas.95.23.13703 |
0.604 |
|
| 1998 |
Le Brocque D, Henry A, Cappai R, Li QX, Tanner JE, Galatis D, Gray C, Holmes S, Underwood JR, Beyreuther K, Masters CL, Evin G. Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products. Biochemistry. 37: 14958-65. PMID 9778373 DOI: 10.1021/Bi981063L |
0.594 |
|
| 1998 |
White AR, Zheng H, Galatis D, Maher F, Hesse L, Multhaup G, Beyreuther K, Masters CL, Cappai R. Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6207-17. PMID 9698314 |
0.514 |
|
| 1998 |
Culvenor JG, Henry A, Hartmann T, Evin G, Galatis D, Friedhuber A, Jayasena UL, Underwood JR, Beyreuther K, Masters CL, Cappai R. Subcellular localization of the Alzheimer's disease amyloid precursor protein and derived polypeptides expressed in a recombinant yeast system. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 5: 79-89. PMID 9686302 DOI: 10.3109/13506129808995285 |
0.537 |
|
| 1998 |
Sberna G, Sáez-Valero J, Li QX, Czech C, Beyreuther K, Masters CL, McLean CA, Small DH. Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease. Journal of Neurochemistry. 71: 723-31. PMID 9681463 DOI: 10.1046/J.1471-4159.1998.71020723.X |
0.566 |
|
| 1998 |
Postuma RB, Martins RN, Cappai R, Beyreuther K, Masters CL, Strickland DK, Mok SS, Small DH. Effects of the amyloid protein precursor of Alzheimer's disease and other ligands of the LDL receptor-related protein on neurite outgrowth from sympathetic neurons in culture. Febs Letters. 428: 13-6. PMID 9645465 DOI: 10.1016/S0014-5793(98)00475-X |
0.559 |
|
| 1998 |
Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K. Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 95: 6460-4. PMID 9600988 DOI: 10.1073/Pnas.95.11.6460 |
0.713 |
|
| 1998 |
Hass S, Fresser F, Köchl S, Beyreuther K, Utermann G, Baier G. Physical interaction of ApoE with amyloid precursor protein independent of the amyloid Abeta region in vitro. The Journal of Biological Chemistry. 273: 13892-7. PMID 9593736 DOI: 10.1074/Jbc.273.22.13892 |
0.532 |
|
| 1998 |
Multhaup G, Ruppert T, Schlicksupp A, Hesse L, Bill E, Pipkorn R, Masters CL, Beyreuther K. Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide. Biochemistry. 37: 7224-30. PMID 9585534 DOI: 10.1021/Bi980022M |
0.463 |
|
| 1998 |
Li QX, Whyte S, Tanner JE, Evin G, Beyreuther K, Masters CL. Secretion of Alzheimer's disease Abeta amyloid peptide by activated human platelets. Laboratory Investigation; a Journal of Technical Methods and Pathology. 78: 461-9. PMID 9564890 |
0.383 |
|
| 1998 |
Hock C, Golombowski S, Müller-Spahn F, Naser W, Beyreuther K, Mönning U, Schenk D, Vigo-Pelfrey C, Bush AM, Moir R, Tanzi RE, Growdon JH, Nitsch RM. Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity. European Neurology. 39: 111-8. PMID 9520072 DOI: 10.1159/000007917 |
0.482 |
|
| 1998 |
Hentschel F, Zerfass R, Becker G, Beyreuther K, Förstl H. [Neuroradiological findings in Alzheimer dementia with the presenile mutation]. Rã¶Fo : Fortschritte Auf Dem Gebiete Der Rã¶Ntgenstrahlen Und Der Nuklearmedizin. 168: 97-100. PMID 9501942 DOI: 10.1055/S-2007-1015189 |
0.335 |
|
| 1998 |
Masters CL, Beyreuther K. Alzheimer's disease. Bmj (Clinical Research Ed.). 316: 446-8. PMID 9492674 DOI: 10.1136/Bmj.316.7129.446 |
0.575 |
|
| 1998 |
Moir RD, Lynch T, Bush AI, Whyte S, Henry A, Portbury S, Multhaup G, Small DH, Tanzi RE, Beyreuther K, Masters CL. Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain. The Journal of Biological Chemistry. 273: 5013-9. PMID 9478949 DOI: 10.1074/Jbc.273.9.5013 |
0.595 |
|
| 1998 |
White AR, Zheng H, Galatis D, Maher F, Hesse L, Multhaup G, Beyreuther K, Masters CL, Cappai R. Survival of Cultured Neurons from Amyloid Precursor Protein Knock-Out Mice against Alzheimer’s Amyloid-β Toxicity and Oxidative Stress The Journal of Neuroscience. 18: 6207-6217. DOI: 10.1523/Jneurosci.18-16-06207.1998 |
0.552 |
|
| 1998 |
Li Q, Cappai R, Evin G, Tanner JE, Gray CW, Beyreuther K, Masters CL. Products of the Alzheimer's disease amyloid precursor protein generated by,β-secretase are present in human platelets, and secreted upon degranulation American Journal of Alzheimer's Disease. 13: 236-244. DOI: 10.1177/153331759801300504 |
0.542 |
|
| 1998 |
Beyreuther K, Masters C. Altering APP trafficing and processing European Neuropsychopharmacology. 8: S100. DOI: 10.1016/S0924-977X(98)80076-X |
0.354 |
|
| 1997 |
Bayer TA, Paliga K, Weggen S, Wiestler OD, Beyreuther K, Multhaup G. Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer's disease. Acta Neuropathologica. 94: 519-24. PMID 9444352 DOI: 10.1007/S004010050745 |
0.563 |
|
| 1997 |
Paliga K, Peraus G, Kreger S, Dürrwang U, Hesse L, Multhaup G, Masters CL, Beyreuther K, Weidemann A. Human amyloid precursor-like protein 1--cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid. European Journal of Biochemistry / Febs. 250: 354-63. PMID 9428684 DOI: 10.1111/J.1432-1033.1997.0354A.X |
0.535 |
|
| 1997 |
Schröder J, Pantel J, Ida N, Essig M, Hartmann T, Knopp MV, Schad LR, Sandbrink R, Sauer H, Masters CL, Beyreuther K. Cerebral changes and cerebrospinal fluid beta-amyloid in Alzheimer's disease: a study with quantitative magnetic resonance imaging. Molecular Psychiatry. 2: 505-7. PMID 9399697 DOI: 10.1038/Sj.Mp.4000313 |
0.502 |
|
| 1997 |
Lichtenthaler SF, Ida N, Multhaup G, Masters CL, Beyreuther K. Mutations in the transmembrane domain of APP altering gamma-secretase specificity. Biochemistry. 36: 15396-403. PMID 9398269 DOI: 10.1021/Bi971071M |
0.597 |
|
| 1997 |
Mills J, Laurent Charest D, Lam F, Beyreuther K, Ida N, Pelech SL, Reiner PB. Regulation of amyloid precursor protein catabolism involves the mitogen-activated protein kinase signal transduction pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9415-22. PMID 9390997 DOI: 10.1523/Jneurosci.17-24-09415.1997 |
0.362 |
|
| 1997 |
Coulson EJ, Barrett GL, Storey E, Bartlett PF, Beyreuther K, Masters CL. Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata. Brain Research. 770: 72-80. PMID 9372205 DOI: 10.1016/S0006-8993(97)00757-9 |
0.582 |
|
| 1997 |
Mok SS, Sberna G, Heffernan D, Cappai R, Galatis D, Clarris HJ, Sawyer WH, Beyreuther K, Masters CL, Small DH. Expression and analysis of heparin-binding regions of the amyloid precursor protein of Alzheimer's disease. Febs Letters. 415: 303-7. PMID 9357988 DOI: 10.1016/S0014-5793(97)01146-0 |
0.5 |
|
| 1997 |
Beyreuther K, Masters CL. Alzheimer's disease. The ins and outs of amyloid-beta. Nature. 389: 677-8. PMID 9338775 DOI: 10.1038/39479 |
0.61 |
|
| 1997 |
Multhaup G, Ruppert T, Schlicksupp A, Hesse L, Beher D, Masters CL, Beyreuther K. Reactive oxygen species and Alzheimer's disease. Biochemical Pharmacology. 54: 533-9. PMID 9337068 DOI: 10.1016/S0006-2952(97)00062-2 |
0.545 |
|
| 1997 |
Culvenor JG, Maher F, Evin G, Malchiodi-Albedi F, Cappai R, Underwood JR, Davis JB, Karran EH, Roberts GW, Beyreuther K, Masters CL. Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment. Journal of Neuroscience Research. 49: 719-31. PMID 9335259 DOI: 10.1002/(Sici)1097-4547(19970915)49:6<719::Aid-Jnr6>3.0.Co;2-A |
0.542 |
|
| 1997 |
McLean CA, Beyreuther K, Masters CL. Commentary on the consensus recommendations for the post mortem diagnosis of Alzheimer's disease. Neurobiology of Aging. 18: S89-90. PMID 9330993 DOI: 10.1016/S0197-4580(97)00061-4 |
0.53 |
|
| 1997 |
Peraus GC, Masters CL, Beyreuther K. Late compartments of amyloid precursor protein transport in SY5Y cells are involved in beta-amyloid secretion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7714-24. PMID 9315893 |
0.56 |
|
| 1997 |
Hartmann T, Bieger SC, Brühl B, Tienari PJ, Ida N, Allsop D, Roberts GW, Masters CL, Dotti CG, Unsicker K, Beyreuther K. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nature Medicine. 3: 1016-20. PMID 9288729 DOI: 10.1038/Nm0997-1016 |
0.539 |
|
| 1997 |
Sberna G, Sáez-Valero J, Beyreuther K, Masters CL, Small DH. The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells. Journal of Neurochemistry. 69: 1177-84. PMID 9282941 DOI: 10.1046/J.1471-4159.1997.69031177.X |
0.526 |
|
| 1997 |
Masters CL, Beyreuther K. Spongiform encephalopathies. Tracking turncoat prion proteins. Nature. 388: 228-9. PMID 9230425 DOI: 10.1038/40752 |
0.473 |
|
| 1997 |
Henry A, Masters CL, Beyreuther K, Cappai R. Expression of human amyloid precursor protein ectodomains in Pichia pastoris: analysis of culture conditions, purification, and characterization. Protein Expression and Purification. 10: 283-91. PMID 9226725 DOI: 10.1006/Prep.1997.0748 |
0.495 |
|
| 1997 |
Czech C, Delaère P, Macq AF, Reibaud M, Dreisler S, Touchet N, Schombert B, Mazadier M, Mercken L, Theisen M, Pradier L, Octave JN, Beyreuther K, Tremp G. Proteolytical processing of mutated human amyloid precursor protein in transgenic mice. Brain Research. Molecular Brain Research. 47: 108-16. PMID 9221907 DOI: 10.1016/S0169-328X(97)00039-9 |
0.456 |
|
| 1997 |
Beyreuther K, Masters CL. Serpents on the road to dementia and death. Accumulating evidence from several studies points to the normal function of presenilin 1 and suggests how the mutant protein contributes to deposition of amyloid plaques in Alzheimer's disease. Nature Medicine. 3: 723-5. PMID 9212094 DOI: 10.1038/Nm0797-723 |
0.596 |
|
| 1997 |
Tienari PJ, Ida N, Ikonen E, Simons M, Weidemann A, Multhaup G, Masters CL, Dotti CG, Beyreuther K. Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 94: 4125-30. PMID 9108116 DOI: 10.1073/Pnas.94.8.4125 |
0.702 |
|
| 1997 |
Weidemann A, Paliga K, Dürrwang U, Czech C, Evin G, Masters CL, Beyreuther K. Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein. Nature Medicine. 3: 328-32. PMID 9055862 DOI: 10.1038/Nm0397-328 |
0.633 |
|
| 1997 |
Clarris HJ, Cappai R, Heffernan D, Beyreuther K, Masters CL, Small DH. Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping. Journal of Neurochemistry. 68: 1164-72. PMID 9048763 DOI: 10.1046/J.1471-4159.1997.68031164.X |
0.493 |
|
| 1997 |
Whyte S, Wilson N, Currie J, Maruff P, Malone V, Shafiq-Antonacci R, Tyler P, Derry KL, Underwood J, Li QX, Beyreuther K, Masters CL. Collection and normal levels of the amyloid precursor protein in plasma. Annals of Neurology. 41: 121-4. PMID 9005877 DOI: 10.1002/Ana.410410122 |
0.512 |
|
| 1997 |
Sandbrink R, Mönning U, Masters CL, Beyreuther K. Expression of the APP gene family in brain cells, brain development and aging. Gerontology. 43: 119-31. PMID 8996834 DOI: 10.1159/000213840 |
0.557 |
|
| 1997 |
Mok SS, Evin G, Li QX, Smith AI, Beyreuther K, Masters CL, Small DH. A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments. Biochemistry. 36: 156-63. PMID 8993329 DOI: 10.1021/Bi961848W |
0.589 |
|
| 1997 |
Drache B, Diehl GE, Beyreuther K, Perlmutter LS, König G. Bcl-xl-specific antibody labels activated microglia associated with Alzheimer's disease and other pathological states. Journal of Neuroscience Research. 47: 98-108. PMID 8981243 DOI: 10.1002/(Sici)1097-4547(19970101)47:1<98::Aid-Jnr11>3.0.Co;2-6 |
0.449 |
|
| 1997 |
Peraus GC, Masters CL, Beyreuther K. Late Compartments of Amyloid Precursor Protein Transport in SY5Y Cells Are Involved in β-Amyloid Secretion The Journal of Neuroscience. 17: 7714-7724. DOI: 10.1523/Jneurosci.17-20-07714.1997 |
0.574 |
|
| 1997 |
Sandbrink R, Beyreuther K. Alzheimer-Krankheit {Wenn die Amyloid-Sanduhr läuft) E-Neuroforum. 3. DOI: 10.1515/Nf-1997-0302 |
0.5 |
|
| 1997 |
Masters CL, Beyreuther K. Clues to the Etiology of Alzheimer's Disease Through the Study of the Amyloid Precursor Protein Brain Pathology. 7: 1037-1037. DOI: 10.1111/J.1750-3639.1997.Tb00970.X |
0.607 |
|
| 1997 |
Masters C, Beyreuther K. Alzheimer's Disease: Unravelling the Genetic and Environmental Pathways Towards Pathogenesis Australian Journal On Ageing. 16: 116-119. DOI: 10.1111/J.1741-6612.1997.Tb01070.X |
0.53 |
|
| 1996 |
Tienari PJ, De Strooper B, Ikonen E, Ida N, Simons M, Masters CL, Dotti CG, Beyreuther K. Neuronal sorting and processing of amyloid precursor protein: implications for Alzheimer's disease. Cold Spring Harbor Symposia On Quantitative Biology. 61: 575-85. PMID 9246484 DOI: 10.1101/Sqb.1996.061.01.058 |
0.586 |
|
| 1996 |
Sandbrink R, Beyreuther K. Unraveling the molecular pathway of Alzheimer's disease: research about presenilins gathers momentum. Molecular Psychiatry. 1: 438-44. PMID 9154244 |
0.342 |
|
| 1996 |
Sandbrink R, Hartmann T, Masters CL, Beyreuther K. Genes contributing to Alzheimer's disease. Molecular Psychiatry. 1: 27-40. PMID 9118312 |
0.348 |
|
| 1996 |
Williamson TG, Mok SS, Henry A, Cappai R, Lander AD, Nurcombe V, Beyreuther K, Masters CL, Small DH. Secreted glypican binds to the amyloid precursor protein of Alzheimer's disease (APP) and inhibits APP-induced neurite outgrowth. The Journal of Biological Chemistry. 271: 31215-21. PMID 8940123 DOI: 10.1074/Jbc.271.49.31215 |
0.578 |
|
| 1996 |
Beyreuther K, Multhaup G, Masters CL. Alzheimer's disease: genesis of amyloid. Ciba Foundation Symposium. 199: 119-27; discussion 1. PMID 8915607 |
0.534 |
|
| 1996 |
Storey E, Beyreuther K, Masters CL. Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components. Brain Research. 735: 217-31. PMID 8911660 DOI: 10.1016/0006-8993(96)00608-7 |
0.506 |
|
| 1996 |
Storey E, Spurck T, Pickett-Heaps J, Beyreuther K, Masters CL. The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites. Brain Research. 735: 59-66. PMID 8905170 DOI: 10.1016/0006-8993(96)00609-9 |
0.522 |
|
| 1996 |
Tienari PJ, De Strooper B, Ikonen E, Simons M, Weidemann A, Czech C, Hartmann T, Ida N, Multhaup G, Masters CL, Van Leuven F, Beyreuther K, Dotti CG. The beta-amyloid domain is essential for axonal sorting of amyloid precursor protein. The Embo Journal. 15: 5218-29. PMID 8895567 |
0.454 |
|
| 1996 |
Sarochan M, Förstl H, Sattel H, Zerfass R, Czech C, Beyreuther K. Apolipoprotein E genotype does not promote the clinical progression of manifest Alzheimer's disease. Dementia (Basel, Switzerland). 7: 120. PMID 8866687 DOI: 10.1159/000106865 |
0.345 |
|
| 1996 |
Thilmann P, Ernst C, Czech C, Kaumeier S, Beyreuther K, Förstl H. Low apolipoprotein E4 allelic frequency in Alzheimer's disease and functional psychiatric disorders. Dementia (Basel, Switzerland). 7: 118-9. PMID 8866686 DOI: 10.1159/000106864 |
0.31 |
|
| 1996 |
Beyreuther K, Masters CL. Alzheimer's disease. Tangle disentanglement. Nature. 383: 476-7. PMID 8849716 DOI: 10.1038/383476a0 |
0.451 |
|
| 1996 |
Ida N, Masters CL, Beyreuther K. Rapid cellular uptake of Alzheimer amyloid betaA4 peptide by cultured human neuroblastoma cells. Febs Letters. 394: 174-8. PMID 8843158 DOI: 10.1016/0014-5793(96)00948-9 |
0.555 |
|
| 1996 |
Bayer TA, Fossgreen A, Czech C, Beyreuther K, Wiestler OD. Plaque formation in brain transplants exposed to human beta-amyloid precursor protein 695. Acta Neuropathologica. 92: 130-7. PMID 8841658 DOI: 10.1007/S004010050500 |
0.52 |
|
| 1996 |
Ida N, Hartmann T, Pantel J, Schröder J, Zerfass R, Förstl H, Sandbrink R, Masters CL, Beyreuther K. Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay. The Journal of Biological Chemistry. 271: 22908-14. PMID 8798471 DOI: 10.1074/Jbc.271.37.22908 |
0.504 |
|
| 1996 |
Sandbrink R, Zhang D, Schaeffer S, Masters CL, Bauer J, Förstl H, Beyreuther K. Missense mutations of the PS-1/S182 gene in German early-onset Alzheimer's disease patients. Annals of Neurology. 40: 265-6. PMID 8773614 DOI: 10.1002/Ana.410400225 |
0.475 |
|
| 1996 |
Hartmann T, Bergsdorf C, Sandbrink R, Tienari PJ, Multhaup G, Ida N, Bieger S, Dyrks T, Weidemann A, Masters CL, Beyreuther K. Alzheimer's disease betaA4 protein release and amyloid precursor protein sorting are regulated by alternative splicing. The Journal of Biological Chemistry. 271: 13208-14. PMID 8662794 DOI: 10.1074/Jbc.271.22.13208 |
0.552 |
|
| 1996 |
Beyreuther K, Multhaup G, Mönning U, Sandbrink R, Beher D, Hesse L, Small DH, Masters CL. Regulation of APP expression, biogenesis and metabolism by extracellular matrix and cytokines. Annals of the New York Academy of Sciences. 777: 74-6. PMID 8624129 DOI: 10.1111/J.1749-6632.1996.Tb34403.X |
0.544 |
|
| 1996 |
Small DH, Williamson T, Reed G, Clarris H, Beyreuther K, Masters CL, Nurcombe V. The role of heparan sulfate proteoglycans in the pathogenesis of Alzheimer's disease. Annals of the New York Academy of Sciences. 777: 316-21. PMID 8624106 DOI: 10.1111/J.1749-6632.1996.Tb34439.X |
0.633 |
|
| 1996 |
Sandbrink R, Masters CL, Beyreuther K. APP gene family. Alternative splicing generates functionally related isoforms. Annals of the New York Academy of Sciences. 777: 281-7. PMID 8624099 DOI: 10.1111/J.1749-6632.1996.Tb34433.X |
0.559 |
|
| 1996 |
Multhaup G, Schlicksupp A, Hesse L, Beher D, Ruppert T, Masters CL, Beyreuther K. The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I) Science (New York, N.Y.). 271: 1406-9. PMID 8596911 DOI: 10.1126/Science.271.5254.1406 |
0.492 |
|
| 1996 |
Simons M, de Strooper B, Multhaup G, Tienari PJ, Dotti CG, Beyreuther K. Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 899-908. PMID 8558258 DOI: 10.1523/Jneurosci.16-03-00899.1996 |
0.458 |
|
| 1996 |
Peraus G, Masters C, Beyreuther K. 791 Targeting of APP-chimeras into the endosomal/lysosomal compartment reduces βA4 generation Neurobiology of Aging. 17: S197. DOI: 10.1016/S0197-4580(96)80793-7 |
0.42 |
|
| 1996 |
Hartmann T, Bergsdorf C, Bieger S, Tienari PJ, Ida N, Multhaup G, Sandbrink R, Weidemann A, Masters CL, Beyreuther K. 789 Exon 15 of APP regulates βA4 production and polarized secretion of APP Neurobiology of Aging. 17: S196. DOI: 10.1016/S0197-4580(96)80791-3 |
0.446 |
|
| 1996 |
Multhaup G, Schlicksupp A, Hesse L, Beher D, Ruppert T, Masters C, Beyreuther K. 619 Reduction of copper(II) to copper(I) by the Amyloid Precursor Protein (APP) of Alzheimer's disease Neurobiology of Aging. 17: S154. DOI: 10.1016/S0197-4580(96)80621-X |
0.459 |
|
| 1996 |
Allsop D, Christie G, Gray C, Holmes S, Markwell R, Owen D, Smith L, Wadsworth H, Ward RV, Hartmann T, Lichtenthaler S, Evin G, Fuller S, Masters CL, Beyreuther K, et al. 588 Studies on inhibition of βA4 formation in APP-751 transfected IMR-32 cells, and SPA4CT transfected SHSYSY cells Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80590-2 |
0.315 |
|
| 1996 |
Lichtenthaler S, Ida N, Masters C, Beyreuther K. 524 Mutations near the C-terminus of βA4 influence the γ-cleavage of A4CT (C99) in COS7 cells Neurobiology of Aging. 17: S130-S131. DOI: 10.1016/S0197-4580(96)80526-4 |
0.376 |
|
| 1996 |
Schmitt H, Yang Y, Nobuo I, Multhaup G, Beyreuther K. 483 Inverse Relationship Between BAPP and BAP Expression in the Pathogenesis of Neuritic Plaques Neurobiology of Aging. 17: S120. DOI: 10.1016/S0197-4580(96)80485-4 |
0.323 |
|
| 1996 |
Bayerl TA, Weggenl S, Foßgreen A, Czech C, Beyreuther K, Wiestler OD. 438 APP 695 induces plaque formation in rat brain transplants Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80440-4 |
0.303 |
|
| 1996 |
Beher D, Peraus G, Schachner M, Masters C, Beyreuther K, Multhaup G. 426 APP shares glycan modifications characteristic of cell adhesion molecules Neurobiology of Aging. 17: S106. DOI: 10.1016/S0197-4580(96)80428-3 |
0.416 |
|
| 1996 |
Hesse L, Beher D, Masters C, Beyreuther K, Multhaup G. 425 Alternative splicing of exon 15 regulates APP conformation Neurobiology of Aging. 17: S106. DOI: 10.1016/S0197-4580(96)80427-1 |
0.438 |
|
| 1996 |
Evin G, Li Q, Culvenor J, Cappai R, Mok S, Hartmanna T, Beyreuther K, Masters C. 401 Characterization of APP γ-secretase activities in human brains Neurobiology of Aging. 17: S100. DOI: 10.1016/S0197-4580(96)80403-9 |
0.444 |
|
| 1996 |
Li Q, Tanner J, Evin G, Gray C, Holmes S, Ida N, Hartmann T, Allsop D, Beyreuther K, Masters C. 400 APP products of β- and γ-secretases are present in human platelets Neurobiology of Aging. 17: S100. DOI: 10.1016/S0197-4580(96)80402-7 |
0.415 |
|
| 1996 |
Le Brogue D, Evin G, Henry A, Cappai R, Fuller S, Beyreuther K, Masters C. 394 Characterisation of APP secretases in P. pastoris transfected with human full length APP695 cDNA Neurobiology of Aging. 17: S98-S99. DOI: 10.1016/S0197-4580(96)80396-4 |
0.474 |
|
| 1996 |
Masters CL, Beyreuther K. 329 Multiple amyloidogenic pathways — where is the therapeutic target? Neurobiology of Aging. 17: S83. DOI: 10.1016/S0197-4580(96)80331-9 |
0.357 |
|
| 1996 |
Whyte S, Currie J, Maruff P, Malone V, Coulson E, Beyreuther K, Masters C. 324 The effect of oral zinc supplementation on the amyloid precursor protein of Alzheimer's disease in human plasma and rat brain Neurobiology of Aging. 17: S82. DOI: 10.1016/S0197-4580(96)80326-5 |
0.534 |
|
| 1996 |
Beyreuther K, Multhaup G, Masters C. 297 Molecular dissection of APP and βA4/Aβ pathology and neurodegeneration in Alzheimer's disease Neurobiology of Aging. 17: S75. DOI: 10.1016/S0197-4580(96)80299-5 |
0.576 |
|
| 1996 |
Paliga K, Weidemann A, Dürrwangs U, Peraus G, Kreger S, Masters C, Beyreuther K. 225 Cloning and characterization of the human amyloid precursor-like protein 1 (APLP1) Neurobiology of Aging. 17: S57. DOI: 10.1016/S0197-4580(96)80227-2 |
0.446 |
|
| 1996 |
De Strooper B, Moechars D, Tienari P, Simons M, Beyreuther K, Dotti C, Van Leuven F. 174 Processing of APP in polarized epithelial cells and neurons: relationships among cell types Neurobiology of Aging. 17: S44-S45. DOI: 10.1016/S0197-4580(96)80176-X |
0.577 |
|
| 1996 |
Sandbrink R, Zhang D, Hartmann T, Bergsdorf C, Paliga K, Schäffer S, Bauer J, Först H, Bickel H, Masters C, Beyreuther K. 45 Missense mutations of the Presenilin I (PSI or 5182) gene in German early-onset Alzheimer's disease Patients Neurobiology of Aging. 17: S12. DOI: 10.1016/S0197-4580(96)80047-9 |
0.359 |
|
| 1996 |
Masters CL, Beyreuther K. Multiple amyloidogenic pathways in Alzheimer's disease — Which is the therapeutic target? European Neuropsychopharmacology. 6: 19-20. DOI: 10.1016/0924-977X(96)87387-1 |
0.487 |
|
| 1996 |
Beyreuther K, Tienari P, Ikonenen E, Multhaup G, Hartmann T, Simons M, Dotti C, Masters C. The amyloid hypothesis in Alzheimer's disease and its implication for therapy: A review of evidence European Neuropsychopharmacology. 6: S4-24-S4-25. DOI: 10.1016/0924-977X(96)82886-0 |
0.529 |
|
| 1995 |
Evin G, Beyreuther K, Masters CL. A synthetic substrate assay for the gamma-secretase of the beta-A4 amyloid of Alzheimer's disease. Journal of Peptide Science : An Official Publication of the European Peptide Society. 1: 132-9. PMID 9222990 DOI: 10.1002/Psc.310010205 |
0.565 |
|
| 1995 |
Urmoneit B, Reinsch C, Turner J, Czech C, Beyreuther K, Dyrks T. Inhibition of beta A4 production by specific modulation of beta-secretase activity. Journal of Molecular Neuroscience : Mn. 6: 23-32. PMID 8562317 DOI: 10.1007/Bf02736756 |
0.416 |
|
| 1995 |
LePage RN, Fosang AJ, Fuller SJ, Murphy G, Evin G, Beyreuther K, Masters CL, Small DH. Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease. Febs Letters. 377: 267-70. PMID 8543065 DOI: 10.1016/0014-5793(95)01358-X |
0.586 |
|
| 1995 |
Fuller SJ, Storey E, Li QX, Smith AI, Beyreuther K, Masters CL. Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein. Biochemistry. 34: 8091-8. PMID 7794922 DOI: 10.1021/Bi00025A015 |
0.515 |
|
| 1995 |
Li QX, Evin G, Small DH, Multhaup G, Beyreuther K, Masters CL. Proteolytic processing of Alzheimer's disease beta A4 amyloid precursor protein in human platelets. The Journal of Biological Chemistry. 270: 14140-7. PMID 7775475 DOI: 10.1074/Jbc.270.23.14140 |
0.551 |
|
| 1995 |
Masters CL, Beyreuther K. Molecular neuropathology of Alzheimer's disease. Arzneimittel-Forschung. 45: 410-2. PMID 7763335 |
0.44 |
|
| 1995 |
Beyreuther K, Masters CL. Neurodegeneration and dementia. Alzheimer's disease as a model. Arzneimittel-Forschung. 45: 347-50. PMID 7763324 |
0.359 |
|
| 1995 |
Mönning U, Sandbrink R, Weidemann A, Banati RB, Masters CL, Beyreuther K. Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells. The Journal of Biological Chemistry. 270: 7104-10. PMID 7706247 DOI: 10.1074/Jbc.270.13.7104 |
0.582 |
|
| 1995 |
Simons M, Ikonen E, Tienari PJ, Cid-Arregui A, Mönning U, Beyreuther K, Dotti CG. Intracellular routing of human amyloid protein precursor: axonal delivery followed by transport to the dendrites. Journal of Neuroscience Research. 41: 121-8. PMID 7674373 DOI: 10.1002/Jnr.490410114 |
0.458 |
|
| 1995 |
Zhan SS, Sandbrink R, Beyreuther K, Schmitt HP. APP with Kunitz type protease inhibitor domain (KPI) correlates with neuritic plaque density but not with cortical synaptophysin immunoreactivity in Alzheimer's disease and non-demented aged subjects: a multifactorial analysis. Clinical Neuropathology. 14: 142-9. PMID 7671455 |
0.411 |
|
| 1995 |
Eckert A, Förstl H, Hartmann H, Czech C, Mönning U, Beyreuther K, Müller WE. The amplifying effect of beta-amyloid on cellular calcium signalling is reduced in Alzheimer's disease. Neuroreport. 6: 1199-202. PMID 7662907 DOI: 10.1097/00001756-199505300-00031 |
0.445 |
|
| 1995 |
Simons M, Tienari PJ, Dotti CG, Beyreuther K. Two-dimensional gel mapping of the processing of the human amyloid precursor protein in rat hippocampal neurons. Febs Letters. 368: 363-6. PMID 7628638 DOI: 10.1016/0014-5793(95)00654-R |
0.48 |
|
| 1995 |
Beer J, Masters CL, Beyreuther K. Cells from peripheral tissues that exhibit high APP expression are characterized by their high membrane fusion activity. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 4: 51-9. PMID 7600184 DOI: 10.1006/Neur.1995.0006 |
0.507 |
|
| 1995 |
Williamson TG, Nurcombe V, Beyreuther K, Masters CL, Small DH. Affinity purification of proteoglycans that bind to the amyloid protein precursor of Alzheimer's disease. Journal of Neurochemistry. 65: 2201-8. PMID 7595508 DOI: 10.1046/J.1471-4159.1995.65052201.X |
0.515 |
|
| 1995 |
Sticht H, Bayer P, Willbold D, Dames S, Hilbich C, Beyreuther K, Frank RW, Rösch P. Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease. European Journal of Biochemistry / Febs. 233: 293-8. PMID 7588758 DOI: 10.1111/J.1432-1033.1995.293_1.X |
0.384 |
|
| 1995 |
De Strooper B, Simons M, Multhaup G, Van Leuven F, Beyreuther K, Dotti CG. Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence. The Embo Journal. 14: 4932-8. PMID 7588622 DOI: 10.1002/J.1460-2075.1995.Tb00176.X |
0.543 |
|
| 1995 |
Evin G, Cappai R, Li QX, Culvenor JG, Small DH, Beyreuther K, Masters CL. Candidate gamma-secretases in the generation of the carboxyl terminus of the Alzheimer's disease beta A4 amyloid: possible involvement of cathepsin D. Biochemistry. 34: 14185-92. PMID 7578016 DOI: 10.1021/Bi00043A024 |
0.594 |
|
| 1995 |
Culvenor JG, Friedhuber A, Fuller SJ, Beyreuther K, Masters CL. Expression of the amyloid precursor protein of Alzheimer's disease on the surface of transfected HeLa cells. Experimental Cell Research. 220: 474-81. PMID 7556457 DOI: 10.1006/excr.1995.1339 |
0.5 |
|
| 1995 |
Clarris HJ, Key B, Beyreuther K, Masters CL, Small DH. Expression of the amyloid protein precursor of Alzheimer's disease in the developing rat olfactory system. Brain Research. Developmental Brain Research. 88: 87-95. PMID 7493410 DOI: 10.1016/0165-3806(95)00083-P |
0.482 |
|
| 1995 |
Small DH, Reed G, Fuller SJ, Masters CL, Weidemann A, Beyreuther K. [18] Proteolytic processing of amyloid protein precursor of Alzheimer's disease Methods in Neurosciences. 23: 317-327. DOI: 10.1016/S1043-9471(06)80129-1 |
0.597 |
|
| 1995 |
Beyreuther K, Masters C. S-16-5 Disease altering therapeutic strategies based on the molecular dissection of the amyloid lesions in Alzheimer's disease European Neuropsychopharmacology. 5: 205-206. DOI: 10.1016/0924-977X(95)90229-7 |
0.447 |
|
| 1994 |
Sandbrink R, Masters CL, Beyreuther K. APP gene family: unique age-associated changes in splicing of Alzheimer's betaA4-amyloid protein precursor. Neurobiology of Disease. 1: 13-24. PMID 9216982 DOI: 10.1006/Nbdi.1994.0003 |
0.581 |
|
| 1994 |
Sandbrink R, Masters CL, Beyreuther K. Beta A4-amyloid protein precursor mRNA isoforms without exon 15 are ubiquitously expressed in rat tissues including brain, but not in neurons. The Journal of Biological Chemistry. 269: 1510-7. PMID 8288617 |
0.306 |
|
| 1994 |
Sandbrink R, Masters CL, Beyreuther K. Similar alternative splicing of a non-homologous domain in beta A4-amyloid protein precursor-like proteins. The Journal of Biological Chemistry. 269: 14227-34. PMID 8188705 |
0.372 |
|
| 1994 |
Czech C, Förstl H, Hentschel F, Mönning U, Besthorn C, Geiger-Kabisch C, Sattel H, Masters C, Beyreuther K. Apolipoprotein E-4 gene dose in clinically diagnosed Alzheimer's disease: prevalence, plasma cholesterol levels and cerebrovascular change. European Archives of Psychiatry and Clinical Neuroscience. 243: 291-2. PMID 8172944 DOI: 10.1007/Bf02191587 |
0.309 |
|
| 1994 |
Small DH, Nurcombe V, Reed G, Clarris H, Moir R, Beyreuther K, Masters CL. A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 2117-27. PMID 8158260 DOI: 10.1523/Jneurosci.14-04-02117.1994 |
0.546 |
|
| 1994 |
Mönning U, Sandbrink R, Banati RB, Masters CL, Beyreuther K. Transforming growth factor beta mediates increase of mature transmembrane amyloid precursor protein in microglial cells. Febs Letters. 342: 267-72. PMID 8150082 DOI: 10.1016/0014-5793(94)80514-8 |
0.559 |
|
| 1994 |
Masters CL, Beyreuther K. Alzheimer's disease: a clearer definition of the genetic components. The Medical Journal of Australia. 160: 243-4. PMID 8107621 DOI: 10.5694/J.1326-5377.1994.Tb125822.X |
0.469 |
|
| 1994 |
Sandbrink R, Masters CL, Beyreuther K. Complete nucleotide and deduced amino acid sequence of rat amyloid protein precursor-like protein 2 (APLP2/APPH): two amino acids length difference to human and murine homologues. Biochimica Et Biophysica Acta. 1219: 167-70. PMID 8086458 DOI: 10.1016/0167-4781(94)90263-1 |
0.425 |
|
| 1994 |
Bush AI, Pettingell WH, Multhaup G, d Paradis M, Vonsattel JP, Gusella JF, Beyreuther K, Masters CL, Tanzi RE. Rapid induction of Alzheimer A beta amyloid formation by zinc. Science (New York, N.Y.). 265: 1464-7. PMID 8073293 DOI: 10.1126/Science.8073293 |
0.557 |
|
| 1994 |
Dyrks T, Mönning U, Beyreuther K, Turner J. Amyloid precursor protein secretion and beta A4 amyloid generation are not mutually exclusive. Febs Letters. 349: 210-4. PMID 8050568 DOI: 10.1016/0014-5793(94)00671-7 |
0.433 |
|
| 1994 |
Beyreuther K, Masters CL. Neurobiology. Catching the culprit prion. Nature. 370: 419-20. PMID 8047160 DOI: 10.1038/370419A0 |
0.393 |
|
| 1994 |
Li QX, Berndt MC, Bush AI, Rumble B, Mackenzie I, Friedhuber A, Beyreuther K, Masters CL. Membrane-associated forms of the beta A4 amyloid protein precursor of Alzheimer's disease in human platelet and brain: surface expression on the activated human platelet. Blood. 84: 133-42. PMID 8018913 DOI: 10.1182/Blood.V84.1.133.Bloodjournal841133 |
0.422 |
|
| 1994 |
Clarris HJ, Nurcombe V, Small DH, Beyreuther K, Masters CL. Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants. Journal of Neuroscience Research. 38: 248-58. PMID 7932862 DOI: 10.1002/Jnr.490380303 |
0.551 |
|
| 1994 |
Osuntokun BO, Ogunniyi A, Akang EE, Aghadiuno PU, Ilori A, Bamgboye EA, Beyreuther K, Masters C. Beta A4-amyloid in the brains of non-demented Nigerian Africans. Lancet. 343: 56. PMID 7905067 DOI: 10.1016/S0140-6736(94)90910-5 |
0.504 |
|
| 1994 |
Czech C, Masters C, Beyreuther K. Alzheimer's disease and transgenic mice. Journal of Neural Transmission. Supplementum. 44: 219-30. PMID 7897394 DOI: 10.1007/978-3-7091-9350-1_17 |
0.564 |
|
| 1994 |
Evin G, Beyreuther K, Masters CL. Alzheimer's disease amyloid precursor protein (ApPP): proteolytic processing, secretases and βA4 amyloid production Amyloid. 1: 263-280. DOI: 10.3109/13506129409146118 |
0.59 |
|
| 1994 |
Thomas LD, Gonzales MF, Chamberlain A, Beyreuther K, Masters CL, Flicker L. Comparison of clinical state, retrospective informant interview and the neuropathologic diagnosis of alzheimer's disease International Journal of Geriatric Psychiatry. 9: 233-236. DOI: 10.1002/Gps.930090309 |
0.427 |
|
| 1993 |
Dyrks T, Dyrks E, Masters CL, Beyreuther K. Amyloidogenicity of rodent and human beta A4 sequences. Febs Letters. 324: 231-6. PMID 8508926 DOI: 10.1016/0014-5793(93)81399-K |
0.507 |
|
| 1993 |
Bush AI, Multhaup G, Moir RD, Williamson TG, Small DH, Rumble B, Pollwein P, Beyreuther K, Masters CL. A novel zinc(II) binding site modulates the function of the beta A4 amyloid protein precursor of Alzheimer's disease. The Journal of Biological Chemistry. 268: 16109-12. PMID 8344894 |
0.382 |
|
| 1993 |
Dyrks T, Dyrks E, Mönning U, Urmoneit B, Turner J, Beyreuther K. Generation of beta A4 from the amyloid protein precursor and fragments thereof. Febs Letters. 335: 89-93. PMID 8243673 DOI: 10.1016/0014-5793(93)80446-2 |
0.437 |
|
| 1993 |
Beyreuther K, Pollwein P, Multhaup G, Mönning U, König G, Dyrks T, Schubert W, Masters CL. Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome. Annals of the New York Academy of Sciences. 695: 91-102. PMID 8239320 DOI: 10.1111/J.1749-6632.1993.Tb23035.X |
0.606 |
|
| 1993 |
Sandbrink R, Banati R, Masters CL, Beyreuther K, König G. Expression of L-APP mRNA in brain cells. Annals of the New York Academy of Sciences. 695: 183-9. PMID 8239280 DOI: 10.1111/J.1749-6632.1993.Tb23049.X |
0.528 |
|
| 1993 |
Bush AI, Beyreuther K, Masters CL. The beta A4 amyloid protein precursor in human circulation. Annals of the New York Academy of Sciences. 695: 175-82. PMID 8239279 DOI: 10.1111/J.1749-6632.1993.Tb23048.X |
0.605 |
|
| 1993 |
Small DH, Nurcombe V, Clarris H, Beyreuther K, Masters CL. The role of extracellular matrix in the processing of the amyloid protein precursor of Alzheimer's disease. Annals of the New York Academy of Sciences. 695: 169-74. PMID 8239278 DOI: 10.1111/J.1749-6632.1993.Tb23047.X |
0.594 |
|
| 1993 |
Guiroy DC, Mellini M, Miyazaki M, Hilbich C, Safar J, Garruto RM, Yanagihara R, Beyreuther K, Gajdusek DC. Neurofibrillary tangles of Guamanian amyotrophic lateral sclerosis, parkinsonism-dementia and neurologically normal Guamanians contain a 4- to 4.5-kilodalton protein which is immunoreactive to anti-amyloid beta/A4-protein antibodies. Acta Neuropathologica. 86: 265-74. PMID 8213085 DOI: 10.1007/Bf00304141 |
0.424 |
|
| 1993 |
Zhan SS, Beyreuther K, Schmitt HP. Vascular dementia in Spatz-Lindenberg's disease (SLD): cortical synaptophysin immunoreactivity as compared with dementia of Alzheimer type and non-demented controls. Acta Neuropathologica. 86: 259-64. PMID 8213084 DOI: 10.1007/Bf00304140 |
0.352 |
|
| 1993 |
Dichgans M, Mönning U, König G, Sandbrink R, Masters CL, Beyreuther K. APP expression in primary neuronal cell cultures from P6 mice during in vitro differentiation. Dementia (Basel, Switzerland). 4: 301-7. PMID 8136892 DOI: 10.1159/000107337 |
0.488 |
|
| 1993 |
Gearing M, Wilson RW, Unger ER, Shelton ER, Chan HW, Masters CL, Beyreuther K, Mirra SS. Amyloid precursor protein (APP) in the striatum in Alzheimer's disease: an immunohistochemical study. Journal of Neuropathology and Experimental Neurology. 52: 22-30. PMID 7678853 DOI: 10.1097/00005072-199301000-00004 |
0.574 |
|
| 1993 |
Banati RB, Gehrmann J, Czech C, Mönning U, Jones LL, König G, Beyreuther K, Kreutzberg GW. Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia. Glia. 9: 199-210. PMID 7507467 DOI: 10.1002/Glia.440090305 |
0.506 |
|
| 1993 |
Hilbich C, Mönning U, Grund C, Masters CL, Beyreuther K. Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11. The Journal of Biological Chemistry. 268: 26571-7. PMID 7504673 |
0.399 |
|
| 1993 |
Evans S, Katona C, Tachibana H, Kawabata K, Tomino Y, Sugita M, Fukuchi M, Caffarra P, Scaglioni A, Malvezzi L, Previdi P, Spreafico L, Salmaso D, Allain H, Belliard S, ... ... Beyreuther K, et al. Contents, Vol. 4, 1993 Dementia and Geriatric Cognitive Disorders. 4: 357-360. DOI: 10.1159/000107347 |
0.313 |
|
| 1993 |
Evans S, Katona C, Tachibana H, Kawabata K, Tomino Y, Sugita M, Fukuchi M, Caffarra P, Scaglioni A, Malvezzi L, Previdi P, Spreafico L, Salmaso D, Allain H, Belliard S, ... ... Beyreuther K, et al. Subject Index Vol. 4, 1993 Dementia and Geriatric Cognitive Disorders. 4: 355-356. DOI: 10.1159/000107346 |
0.319 |
|
| 1992 |
Pollwein P, Masters CL, Beyreuther K. The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter. Nucleic Acids Research. 20: 63-8. PMID 1738605 DOI: 10.1093/Nar/20.1.63 |
0.39 |
|
| 1992 |
Milward EA, Papadopoulos R, Fuller SJ, Moir RD, Small D, Beyreuther K, Masters CL. The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron. 9: 129-37. PMID 1632967 DOI: 10.1016/0896-6273(92)90228-6 |
0.589 |
|
| 1992 |
König G, Mönning U, Czech C, Prior R, Banati R, Schreiter-Gasser U, Bauer J, Masters CL, Beyreuther K. Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells. The Journal of Biological Chemistry. 267: 10804-9. PMID 1587857 |
0.365 |
|
| 1992 |
Dyrks T, Dyrks E, Hartmann T, Masters C, Beyreuther K. Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation. The Journal of Biological Chemistry. 267: 18210-7. PMID 1517249 |
0.335 |
|
| 1992 |
Dyrks T, Dyrks E, Masters C, Beyreuther K. Membrane inserted APP fragments containing the beta A4 sequence of Alzheimer's disease do not aggregate. Febs Letters. 309: 20-4. PMID 1511741 DOI: 10.1016/0014-5793(92)80730-5 |
0.575 |
|
| 1992 |
Hilbich C, Kisters-Woike B, Reed J, Masters CL, Beyreuther K. Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides. Journal of Molecular Biology. 228: 460-73. PMID 1453457 DOI: 10.1016/0022-2836(92)90835-8 |
0.553 |
|
| 1992 |
Mönning U, König G, Banati RB, Mechler H, Czech C, Gehrmann J, Schreiter-Gasser U, Masters CL, Beyreuther K. Alzheimer beta A4-amyloid protein precursor in immunocompetent cells. The Journal of Biological Chemistry. 267: 23950-6. PMID 1429732 |
0.364 |
|
| 1992 |
Beyreuther K, Dyrks T, Hilbich C, Mönning U, König G, Multhaup G, Pollwein P, Masters CL. Amyloid precursor protein (APP) and beta A4 amyloid in Alzheimer's disease and Down syndrome. Progress in Clinical and Biological Research. 379: 159-82. PMID 1409743 |
0.433 |
|
| 1992 |
Moir RD, Martins RN, Bush AI, Small DH, Milward EA, Rumble BA, Multhaup G, Beyreuther K, Masters CL. Human brain beta A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization. Journal of Neurochemistry. 59: 1490-8. PMID 1402900 DOI: 10.1111/J.1471-4159.1992.Tb08465.X |
0.605 |
|
| 1992 |
Soininen H, Syrjänen S, Heinonen O, Neittaanmäki H, Miettinen R, Paljärvi L, Syrjänen K, Beyreuther K, Riekkinen P. Amyloid beta-protein deposition in skin of patients with dementia. Lancet. 339: 245. PMID 1346198 DOI: 10.1016/0140-6736(92)90046-6 |
0.431 |
|
| 1992 |
Prior P, Schmitt B, Grenningloh G, Pribilla I, Multhaup G, Beyreuther K, Maulet Y, Werner P, Langosch D, Kirsch J. Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein. Neuron. 8: 1161-70. PMID 1319186 DOI: 10.1016/0896-6273(92)90136-2 |
0.336 |
|
| 1992 |
Bush AI, Beyreuther K, Masters CL. Beta A4 amyloid protein and its precursor in Alzheimer's disease. Pharmacology & Therapeutics. 56: 97-117. PMID 1297146 DOI: 10.1016/0163-7258(92)90039-3 |
0.609 |
|
| 1992 |
Small DH, Nurcombe V, Moir R, Michaelson S, Monard D, Beyreuther K, Masters CL. Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4143-50. PMID 1279136 DOI: 10.1523/Jneurosci.12-11-04143.1992 |
0.527 |
|
| 1992 |
Fuller S, Milward E, Barry J, Li Q, Masters C, Beyreuther K. Monoclonal antibodies to the carboxyl-terminus of the amyloid precursor protein of alzheimer’s disease Pathology. 24: 24. DOI: 10.1016/S0031-3025(16)35970-0 |
0.58 |
|
| 1992 |
Bush A, Williamson T, Moir R, Li Q, Currie J, Small D, Rumble B, Mönning U, Beyreuther K, Masters C. Plasma amyloid precursor protein is a marker for alzheimer’s disease Pathology. 24: 24. DOI: 10.1016/S0031-3025(16)35969-4 |
0.581 |
|
| 1992 |
Rumble B, Small D, Moir R, Bush A, Masters C, Beyreuther K. Plasma kallikrein may process the amyloid protein precursor of alzheimer’s disease Pathology. 24: 24. DOI: 10.1016/S0031-3025(16)35968-2 |
0.593 |
|
| 1992 |
Li O, Bush A, Mackenzie I, Friedhuber A, Beyreuther K, Masters C. Characterization of a membrane bound form of the amyloid protein precursor (APP) of alzheimer’s disease Pathology. 24: 9. DOI: 10.1016/S0031-3025(16)35914-1 |
0.509 |
|
| 1992 |
Kilskinen M, Halmektö M, Alhonen L, Jänne J, Syrjänen S, Syrjänen K, Miettinen R, Heinonen O, Beyreuther K, Riekkinen P. Transgenic mice expressing the human β-amyloid peptide encoding sequence Neurobiology of Aging. 13. DOI: 10.1016/0197-4580(92)90523-Z |
0.343 |
|
| 1992 |
Banati R, Gehrmann J, Czech C, Mönning U, König G, Beyreuther K, Kreutzberg G. Amyloid precursor protein is rapidly expressed in glia associated with reactive neurons Neurobiology of Aging. 13: S87. DOI: 10.1016/0197-4580(92)90472-A |
0.399 |
|
| 1992 |
Milward E, Papadopoulos R, Moir R, Fuller S, Dottori M, Beyreuther K, Masters C. βA4 amyloid protein precursor of Alzheimer's disease: Evidence for neurotrophic and cytotoxic actions Neurobiology of Aging. 13: S79. DOI: 10.1016/0197-4580(92)90440-9 |
0.602 |
|
| 1992 |
Whyte S, Bush AI, Currie J, Williamson TG, Tiggelen CJV, Small DH, Moir RD, Rumble B, Thomas LD, Li Q, Mönning U, Beyreuther K, Masters CL. The abnormality of plasma amyloid protein precursor in Alzheimer's disease Neurobiology of Aging. 13. DOI: 10.1016/0197-4580(92)90241-O |
0.568 |
|
| 1992 |
Multhaup G, Bush AI, Pollwein P, Masters CL, Beyreuther K. Specific binding of the alzheimer βA4 amyloid precursor to collagen, laminin, and heparin Journal of Protein Chemistry. 11: 398-399. DOI: 10.1007/Bf01673756 |
0.545 |
|
| 1991 |
Richards SJ, Waters JJ, Rogers DC, Martel FL, Sparkman DR, White CL, Beyreuther K, Masters CL, Dunnett SB. Hippocampal grafts derived from embryonic trisomy 16 mice exhibit amyloid (A4) and neurofibrillary pathology. Progress in Brain Research. 82: 215-23. PMID 2149769 DOI: 10.1016/S0079-6123(08)62607-2 |
0.438 |
|
| 1991 |
Hilbich C, Kisters-Woike B, Reed J, Masters CL, Beyreuther K. Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease. Journal of Molecular Biology. 218: 149-63. PMID 2002499 DOI: 10.1016/0022-2836(91)90881-6 |
0.516 |
|
| 1991 |
Martin JJ, Gheuens J, Bruyland M, Cras P, Vandenberghe A, Masters CL, Beyreuther K, Dom R, Ceuterick C, Lübke U. Early-onset Alzheimer's disease in 2 large Belgian families. Neurology. 41: 62-8. PMID 1985297 DOI: 10.1212/Wnl.41.1.62 |
0.549 |
|
| 1991 |
Hilbich C, Kisters-Woike B, Reed J, Masters CL, Beyreuther K. Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4. European Journal of Biochemistry / Febs. 201: 61-9. PMID 1915378 DOI: 10.1111/J.1432-1033.1991.Tb16256.X |
0.525 |
|
| 1991 |
Bauer J, König G, Strauss S, Jonas U, Ganter U, Weidemann A, Mönning U, Masters CL, Volk B, Berger M, Beyreuther K. In‐vitro matured human macrophages express Alzheimer's βA4‐amyloid precursor protein indicating synthesis in microglial cells Febs Letters. 282: 335-340. PMID 1903718 DOI: 10.1016/0014-5793(91)80508-Z |
0.568 |
|
| 1991 |
Martin LJ, Sisodia SS, Koo EH, Cork LC, Dellovade TL, Weidemann A, Beyreuther K, Masters C, Price DL. Amyloid precursor protein in aged nonhuman primates. Proceedings of the National Academy of Sciences of the United States of America. 88: 1461-5. PMID 1899927 DOI: 10.1073/Pnas.88.4.1461 |
0.697 |
|
| 1991 |
König G, Salbaum JM, Wiestler O, Lang W, Schmitt HP, Masters CL, Beyreuther K. Alternative splicing of the beta A4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients. Brain Research. Molecular Brain Research. 9: 259-62. PMID 1851528 DOI: 10.1016/0169-328X(91)90010-U |
0.565 |
|
| 1991 |
Martins RN, Robinson PJ, Chleboun JO, Beyreuther K, Masters CL. The molecular pathology of amyloid deposition in Alzheimer's disease. Molecular Neurobiology. 5: 389-98. PMID 1823142 DOI: 10.1007/Bf02935560 |
0.592 |
|
| 1991 |
Schubert W, Prior R, Weidemann A, Dircksen H, Multhaup G, Masters CL, Beyreuther K. Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites. Brain Research. 563: 184-94. PMID 1786532 DOI: 10.1016/0006-8993(91)91532-6 |
0.546 |
|
| 1991 |
Beyreuther K, Bush AI, Dyrks T, Hilbich C, König G, Mönning U, Multhaup G, Prior R, Rumble B, Schubert W. Mechanisms of amyloid deposition in Alzheimer's disease. Annals of the New York Academy of Sciences. 640: 129-39. PMID 1776729 DOI: 10.1111/J.1749-6632.1991.Tb00204.X |
0.569 |
|
| 1991 |
Small DH, Moir RD, Fuller SJ, Michaelson S, Bush AI, Li QX, Milward E, Hilbich C, Weidemann A, Beyreuther K. A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease. Biochemistry. 30: 10795-9. PMID 1718425 DOI: 10.1021/Bi00108A027 |
0.535 |
|
| 1991 |
Ganter U, Strauss S, Jonas U, Weidemann A, Beyreuther K, Volk B, Berger M, Bauer J. Alpha 2-macroglobulin synthesis in interleukin-6-stimulated human neuronal (SH-SY5Y neuroblastoma) cells. Potential significance for the processing of Alzheimer beta-amyloid precursor protein. Febs Letters. 282: 127-31. PMID 1709116 DOI: 10.1016/0014-5793(91)80460-K |
0.448 |
|
| 1991 |
Yamaguchi F, Richards SJ, Beyreuther K, Salbaum M, Carlson GA, Dunnett SB. Transgenic mice for the amyloid precursor protein 695 isoform have impaired spatial memory. Neuroreport. 2: 781-4. PMID 1686563 DOI: 10.1097/00001756-199112000-00013 |
0.373 |
|
| 1991 |
Ohgami T, Kitamoto T, Weidmann A, Beyreuther K, Tateishi J. Alzheimer's amyloid precursor protein-positive degenerative neurites exist even within kuru plaques not specific to Alzheimer's disease. The American Journal of Pathology. 139: 1245-50. PMID 1684265 |
0.443 |
|
| 1991 |
Gajdusek DC, Beyreuther K, Brown P, Cork LC, Cunningham DD, Frangione B, Gibbs CJ, Goldfarb LG, Goldgaber D, Hsiao KK. Regulation and genetic control of brain amyloid. FESN Study Group. Brain Research. Brain Research Reviews. 16: 83-114. PMID 1677826 DOI: 10.1016/0165-0173(91)90021-Y |
0.317 |
|
| 1991 |
Kitamoto T, Muramoto T, Hilbich C, Beyreuther K, Tateishi J. N-terminal sequence of prion protein is also integrated into kuru plaques in patients with Gerstmann-Sträussler syndrome. Brain Research. 545: 319-21. PMID 1677605 DOI: 10.1016/0006-8993(91)91306-L |
0.344 |
|
| 1991 |
Prior R, Mönning U, Schreiter-Gasser U, Weidemann A, Blennow K, Gottfries CG, Masters CL, Beyreuther K. Quantitative changes in the amyloid beta A4 precursor protein in Alzheimer cerebrospinal fluid. Neuroscience Letters. 124: 69-73. PMID 1677459 DOI: 10.1016/0304-3940(91)90824-D |
0.589 |
|
| 1991 |
Beyreuther K, Masters CL. Amyloid precursor protein (APP) and beta A4 amyloid in the etiology of Alzheimer's disease: precursor-product relationships in the derangement of neuronal function. Brain Pathology (Zurich, Switzerland). 1: 241-51. PMID 1669714 DOI: 10.1111/J.1750-3639.1991.Tb00667.X |
0.614 |
|
| 1991 |
Masters CL, Beyreuther K. Alzheimer's disease: molecular basis of structural lesions. Brain Pathology (Zurich, Switzerland). 1: 226-7. PMID 1669713 DOI: 10.1111/J.1750-3639.1991.Tb00665.X |
0.463 |
|
| 1991 |
Mackenzie I, McKelvie P, Beyreuther K, Masters C. βA4 Amyloid Protein Deposition in the Cerebellum in Alzheimer's Disease and Down's Syndrome Dementia and Geriatric Cognitive Disorders. 2: 237-242. DOI: 10.1159/000107211 |
0.561 |
|
| 1991 |
Beyreuther K, Masters C. Molecular processes associated with Alzheimer's disease European Neuropsychopharmacology. 1: 346-348. DOI: 10.1016/0924-977X(91)90557-B |
0.502 |
|
| 1991 |
Richards SJ, Waters JJ, Beyreuther K, Masters CL, Wischik CM, Sparkman DR, White CL, Abraham CR, Dunnett SB. Transplants of mouse trisomy 16 hippocampus provide a model of Alzheimer's disease neuropathology. The Embo Journal. 10: 297-303. DOI: 10.1002/J.1460-2075.1991.Tb07950.X |
0.512 |
|
| 1990 |
Rupp RA, Kruse U, Multhaup G, Göbel U, Beyreuther K, Sippel AE. Chicken NFI/TGGCA proteins are encoded by at least three independent genes: NFI-A, NFI-B and NFI-C with homologues in mammalian genomes. Nucleic Acids Research. 18: 2607-16. PMID 2339052 DOI: 10.1093/Nar/18.9.2607 |
0.34 |
|
| 1990 |
Walker LC, Masters C, Beyreuther K, Price DL. Amyloid in the brains of aged squirrel monkeys. Acta Neuropathologica. 80: 381-7. PMID 2239150 DOI: 10.1007/Bf00307691 |
0.482 |
|
| 1990 |
König G, Masters CL, Beyreuther K. Retinoic acid induced differentiated neuroblastoma cells show increased expression of the beta A4 amyloid gene of Alzheimer's disease and an altered splicing pattern. Febs Letters. 269: 305-10. PMID 2205513 DOI: 10.1016/0014-5793(90)81181-M |
0.557 |
|
| 1990 |
Mönning U, König G, Prior R, Mechler H, Schreiter-Gasser U, Masters CL, Beyreuther K. Synthesis and secretion of Alzheimer amyloid beta A4 precursor protein by stimulated human peripheral blood leucocytes. Febs Letters. 277: 261-6. PMID 2125277 DOI: 10.1016/0014-5793(90)80861-C |
0.528 |
|
| 1990 |
Beyreuther K, Masters CL. Nomenclature of amyloid A4 proteins and their precursors in Alzheimer's disease and Down's syndrome. Neurobiology of Aging. 11: 66-8. PMID 1970128 DOI: 10.1016/0197-4580(90)90067-A |
0.55 |
|
| 1990 |
Sisodia SS, Koo EH, Beyreuther K, Unterbeck A, Price DL. Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing. Science (New York, N.Y.). 248: 492-5. PMID 1691865 DOI: 10.1126/Science.1691865 |
0.672 |
|
| 1990 |
Koo EH, Sisodia SS, Archer DR, Martin LJ, Weidemann A, Beyreuther K, Fischer P, Masters CL, Price DL. Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport. Proceedings of the National Academy of Sciences of the United States of America. 87: 1561-5. PMID 1689489 DOI: 10.1073/Pnas.87.4.1561 |
0.696 |
|
| 1990 |
Walker LC, Masters C, Beyreuther K, Price DL. CEREBRAL AMYLOID ANGIOPATHY IN AGED SQUIRREL MONKEYS Journal of Neuropathology and Experimental Neurology. 49: 299. DOI: 10.1097/00005072-199005000-00122 |
0.456 |
|
| 1990 |
Wilson RW, Unger ER, Shelton ER, Chan HW, Beyreuther K, Masters CL, Mirra SS. COMPARATIVE IMMUNOCYTOCHEMICAL AND ELECTRON MICROSCOPIC (EM) STUDY OF DIFFUSE AND NEURITIC PLAQUES IN ALZHEIMERʼS DISEASE (AD) Journal of Neuropathology and Experimental Neurology. 49: 267. DOI: 10.1097/00005072-199005000-00026 |
0.478 |
|
| 1990 |
Mönning U, Schreiter-Gasser U, Hilbich C, Bunke D, Prior R, Masters CL, Beyreuther K. Alzheimer amyloid BA4-protein reactive antibodies in human sera and CSF Neurobiology of Aging. 11: 338. DOI: 10.1016/0197-4580(90)90904-E |
0.423 |
|
| 1990 |
Prior R, Mönning U, Weidemann A, Fischer P, Blennow K, Gottfries CG, Beyreuther K. Quantitative determination of the amyloid A4 precursor protein in cerebrospinal fluid Neurobiology of Aging. 11: 333. DOI: 10.1016/0197-4580(90)90883-2 |
0.378 |
|
| 1990 |
Masters CL, Bush A, Evin G, Fuller S, Li Q, Mackenzie I, Milward E, Moir R, Small D, Beyreuther K. The βA4 amyloid protein and its precursors as biological markers for Alzheimer's disease Neurobiology of Aging. 11: 330-331. DOI: 10.1016/0197-4580(90)90874-Y |
0.597 |
|
| 1990 |
Beer J, Salbaum J, Schlichtmann E, Hoppe P, Earley S, Masters C, Carlson G, Beyreuther K. Transgenic mice and Alzheimer's disease Neurobiology of Aging. 11: 326. DOI: 10.1016/0197-4580(90)90855-T |
0.371 |
|
| 1990 |
Weidemann A, Mechler H, Masters CL, Beyreuther K. Processing of precursors of amyloid A4 protein in Alzheimer's disease Neurobiology of Aging. 11: 323. DOI: 10.1016/0197-4580(90)90844-P |
0.577 |
|
| 1990 |
Hilbich C, Kisters-Woike B, Reed J, Grundt C, Masters CL, Franke WW, Beyreuther K. Amyloid of Alzheimer's disease: Structure-function-relationships and peptide inhibitors of fibril formation Neurobiology of Aging. 11: 302. DOI: 10.1016/0197-4580(90)90756-P |
0.447 |
|
| 1990 |
Dyrks T, Mack-Kühn E, Masters C, Beyreuther K. Aggregation and amyloidogenicity of fragments of the amyloid A4 protein precursor of Alzheimer's disease Neurobiology of Aging. 11: 301. DOI: 10.1016/0197-4580(90)90754-N |
0.589 |
|
| 1990 |
König G, Masters CL, Beyreuther K. Induced neuronal expression and alternative splicing pattern of the amyloid gene of Alzheimer's disease Neurobiology of Aging. 11: 301. DOI: 10.1016/0197-4580(90)90753-M |
0.534 |
|
| 1990 |
Beyreuther K, Schubert W, Multhaup G, Salbaum J, Beer J, Hilbich C, König G, Dyrks T, Weidemann A, Fischer P, Bunke D, Monning U, Catteruccia N, Mechler H, Prior R, et al. Amyloid BA4 protein pathology is central to the cause of Alzheimer's disease Neurobiology of Aging. 11: 299. DOI: 10.1016/0197-4580(90)90745-L |
0.6 |
|
| 1990 |
Bunke D, Kypta RM, Mönning U, Courtneidge SA, Masters CL, Beyreuther KT. Alzheimer protein precursors: Tyrosine phosphorylation of the cytoplasmic domain Neurobiology of Aging. 11: 284. DOI: 10.1016/0197-4580(90)90684-R |
0.401 |
|
| 1989 |
Lemaire HG, Salbaum JM, Multhaup G, Kang J, Bayney RM, Unterbeck A, Beyreuther K, Müller-Hill B. The PreA4(695) precursor protein of Alzheimer's disease A4 amyloid is encoded by 16 exons. Nucleic Acids Research. 17: 517-22. PMID 2783775 DOI: 10.1093/Nar/17.2.517 |
0.476 |
|
| 1989 |
Rozemuller JM, Eikelenboom P, Stam FC, Beyreuther K, Masters CL. A4 protein in Alzheimer's disease: primary and secondary cellular events in extracellular amyloid deposition. Journal of Neuropathology and Experimental Neurology. 48: 674-91. PMID 2677252 DOI: 10.1097/00005072-198911000-00009 |
0.585 |
|
| 1989 |
Müller-Hill B, Beyreuther K. Molecular biology of Alzheimer's disease. Annual Review of Biochemistry. 58: 287-307. PMID 2673012 DOI: 10.1146/Annurev.Bi.58.070189.001443 |
0.396 |
|
| 1989 |
Hyman BT, Van Hoesen GW, Beyreuther K, Masters CL. A4 amyloid protein immunoreactivity is present in Alzheimer's disease neurofibrillary tangles. Neuroscience Letters. 101: 352-5. PMID 2671814 DOI: 10.1016/0304-3940(89)90559-4 |
0.639 |
|
| 1989 |
Weidemann A, König G, Bunke D, Fischer P, Salbaum JM, Masters CL, Beyreuther K. Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell. 57: 115-26. PMID 2649245 DOI: 10.1016/0092-8674(89)90177-3 |
0.586 |
|
| 1989 |
Ghetti B, Tagliavini F, Masters CL, Beyreuther K, Giaccone G, Verga L, Farlow MR, Conneally PM, Dlouhy SR, Azzarelli B. Gerstmann-Sträussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family. Neurology. 39: 1453-61. PMID 2573006 DOI: 10.1212/Wnl.39.11.1453 |
0.495 |
|
| 1989 |
Masters CL, Beyreuther KT. The pathology of the amyloid A4 precursor of Alzheimer's disease. Annals of Medicine. 21: 89-90. PMID 2569883 DOI: 10.3109/07853898909149190 |
0.53 |
|
| 1989 |
Rumble B, Retallack R, Hilbich C, Simms G, Multhaup G, Martins R, Hockey A, Montgomery P, Beyreuther K, Masters CL. Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease. The New England Journal of Medicine. 320: 1446-52. PMID 2566117 DOI: 10.1056/Nejm198906013202203 |
0.552 |
|
| 1989 |
Nochlin D, Sumi SM, Bird TD, Snow AD, Leventhal CM, Beyreuther K, Masters CL. Familial dementia with PrP-positive amyloid plaques: a variant of Gerstmann-Sträussler syndrome. Neurology. 39: 910-8. PMID 2500619 DOI: 10.1212/Wnl.39.7.910 |
0.573 |
|
| 1989 |
Beyreuther K, Weidemann A, Dyrks T, Bunke D, Hilbich C, Fischer P, Schubert W, Salbaum M, Multhaup G, Masters CL. The amyloid gene and neuronal dysfunction in Alzheimer's disease Journal of Neural Transmission - Parkinson's Disease and Dementia Section. 1: 5-5. DOI: 10.1007/BF02312186 |
0.473 |
|
| 1989 |
Haass C, Pesold-Hurt B, Multhaup G, Beyreuther K, Kloetzel P. The PROS-35 gene encodes the 35 kd protein subunit of Drosophila melanogaster proteasome. The Embo Journal. 8: 2373-2379. DOI: 10.1002/J.1460-2075.1989.Tb08366.X |
0.301 |
|
| 1988 |
Masters CL, Beyreuther K. The blood-brain barrier in Alzheimer's disease and normal aging. Neurobiology of Aging. 9: 43-4. PMID 3380251 DOI: 10.1016/S0197-4580(88)80015-0 |
0.472 |
|
| 1988 |
Davies L, Wolska B, Hilbich C, Multhaup G, Martins R, Simms G, Beyreuther K, Masters CL. A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques. Neurology. 38: 1688-93. PMID 3054625 DOI: 10.1212/Wnl.38.11.1688 |
0.546 |
|
| 1988 |
Masters CL, Beyreuther K. Neuropathology of unconventional virus infections: molecular pathology of spongiform change and amyloid plaque deposition. Ciba Foundation Symposium. 135: 24-36. PMID 3044707 DOI: 10.1002/9780470513613.CH3 |
0.48 |
|
| 1988 |
Hope J, Reekie LJ, Hunter N, Multhaup G, Beyreuther K, White H, Scott AC, Stack MJ, Dawson M, Wells GA. Fibrils from brains of cows with new cattle disease contain scrapie-associated protein. Nature. 336: 390-2. PMID 2904126 DOI: 10.1038/336390A0 |
0.397 |
|
| 1988 |
Hope J, Multhaup G, Reekie LJ, Kimberlin RH, Beyreuther K. Molecular pathology of scrapie-associated fibril protein (PrP) in mouse brain affected by the ME7 strain of scrapie. European Journal of Biochemistry. 172: 271-7. PMID 2894984 DOI: 10.1111/J.1432-1033.1988.Tb13883.X |
0.368 |
|
| 1988 |
SALBAUM JM, MASTERS CL, BEYREUTHER K. PROMOTER OF ALZHEIMER??S DISEASE AMYLOID A4 PRECURSOR GENE Alzheimer Disease & Associated Disorders. 2: 280. DOI: 10.1097/00002093-198802030-00129 |
0.544 |
|
| 1988 |
BEYREUTHER K, MASTERS CL. ALZHEIMER??S DISEASE AND THE AMYLOID GENE Alzheimer Disease & Associated Disorders. 2: 276. DOI: 10.1097/00002093-198802030-00125 |
0.559 |
|
| 1988 |
Tan N, Mastaglia FL, Masters CL, Beyreuther K, Kakulas BA. AMYLOID (A4) PROTEIN DEPOSITION IN BRAIN IN PROGRESSIVE SUPRANUCLEAR PALSY (PSP) Alzheimer Disease & Associated Disorders. 2: 264. DOI: 10.1097/00002093-198802030-00113 |
0.443 |
|
| 1988 |
HILBICH C, KISTERS B, MASTERS CL, BEYREUTHER K. AMYLOIDOGENICITY OF ALZHEIMER??S DISEASE-SPECIFIC AMYLOID A4 PROTEIN Alzheimer Disease & Associated Disorders. 2: 258. DOI: 10.1097/00002093-198802030-00107 |
0.574 |
|
| 1988 |
DYRKS T, WEIDEMANN A, MULTHAUP G, SALBAUM JM, MASTERS CL, BEYREUTHER K. MOLECULAR PATHOLOGY OF THE AMYLOID A4 PRECURSOR OF ALZHEIMER??S DISEASE Alzheimer Disease & Associated Disorders. 2: 257. DOI: 10.1097/00002093-198802030-00106 |
0.556 |
|
| 1988 |
Mastaglia FL, Masters CL, Beyreuther K, Kakulas BA. DEPOSITION OF AMYLOID (A4) PROTEIN IN THE CEREBRAL CORTEX IN PARKINSON??S DISEASE (PD) Alzheimer Disease & Associated Disorders. 2: 245. DOI: 10.1097/00002093-198802030-00094 |
0.392 |
|
| 1988 |
WEIDEMANN A, K??NIG G, MASTERS CL, BEYREUTHER K. ALZHEIMER??S DISEASE AMYLOID A4 PRECURSOR GENE PRODUCTS Alzheimer Disease & Associated Disorders. 2: 181. DOI: 10.1097/00002093-198802030-00030 |
0.537 |
|
| 1988 |
Salbaum JM, Weidemann A, Lemaire HG, Masters CL, Beyreuther K. The promoter of Alzheimer's disease amyloid A4 precursor gene. The Embo Journal. 7: 2807-2813. DOI: 10.1002/J.1460-2075.1988.Tb03136.X |
0.398 |
|
| 1988 |
Shivers BD, Hilbich C, Multhaup G, Salbaum M, Beyreuther K, Seeburg PH. Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact. The Embo Journal. 7: 1365-1370. DOI: 10.1002/J.1460-2075.1988.Tb02952.X |
0.456 |
|
| 1988 |
Dyrks T, Weidemann A, Multhaup G, Salbaum JM, Lemaire HG, Kang J, Müller-Hill B, Masters CL, Beyreuther K. Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease. The Embo Journal. 7: 949-957. DOI: 10.1002/J.1460-2075.1988.Tb02900.X |
0.547 |
|
| 1987 |
Masters CL, Beyreuther K. Neuronal origin of cerebral amyloidogenic proteins: their role in Alzheimer's disease and unconventional virus diseases of the nervous system. Ciba Foundation Symposium. 126: 49-64. PMID 3556089 DOI: 10.1002/9780470513422.ch4 |
0.557 |
|
| 1987 |
Masters CL, Beyreuther K. The structure of amyloid filaments in Alzheimer's disease and the unconventional virus infections of the nervous system. Psychological Medicine. 16: 735-7. PMID 3547446 DOI: 10.1017/S0033291700011739 |
0.507 |
|
| 1987 |
Dahr W, Wilkinson S, Issitt PD, Beyreuther K, Hummel M, Morel P. High frequency antigens of human erythrocyte membrane sialoglycoproteins, III. Studies on the EnaFR, Wrb and Wra antigens. Biological Chemistry Hoppe-Seyler. 367: 1033-45. PMID 3539140 DOI: 10.1515/Bchm3.1986.367.2.1033 |
0.309 |
|
| 1987 |
Guiroy DC, Miyazaki M, Multhaup G, Fischer P, Garruto RM, Beyreuther K, Masters CL, Simms G, Gibbs CJ, Gajdusek DC. Amyloid of neurofibrillary tangles of Guamanian parkinsonism-dementia and Alzheimer disease share identical amino acid sequence. Proceedings of the National Academy of Sciences of the United States of America. 84: 2073-7. PMID 3470778 DOI: 10.1073/Pnas.84.7.2073 |
0.608 |
|
| 1987 |
Pohlner J, Halter R, Beyreuther K, Meyer TF. Gene structure and extracellular secretion of Neisseria gonorrhoeae IgA protease. Nature. 325: 458-62. PMID 3027577 DOI: 10.1038/325458A0 |
0.302 |
|
| 1987 |
Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, Multhaup G, Beyreuther K, Müller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature. 325: 733-6. PMID 2881207 DOI: 10.1038/325733A0 |
0.597 |
|
| 1987 |
Dahr W, Beyreuther K, Moulds JJ. Structural analysis of the major human erythrocyte membrane sialoglycoprotein from Miltenberger class VII cells. European Journal of Biochemistry. 166: 27-30. PMID 2439339 DOI: 10.1111/J.1432-1033.1987.Tb13478.X |
0.302 |
|
| 1987 |
Masters CL, Beyreuther K. AMYLOIDOGENIC PROTEIN PRECURSORS IN ALZHEIMERʼS DISEASE AND UNCONVENTIONAL VIRUS DISEASES Journal of Neuropathology and Experimental Neurology. 46: 395. DOI: 10.1097/00005072-198705000-00198 |
0.461 |
|
| 1986 |
Hope J, Morton L, Farquhar C, Multhaup G, Beyreuther K, Kimberlin R. The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP). The Embo Journal. 5: 2591-2597. DOI: 10.1002/J.1460-2075.1986.Tb04539.X |
0.373 |
|
| 1985 |
Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. 82: 4245-9. PMID 3159021 DOI: 10.1073/Pnas.82.12.4245 |
0.586 |
|
| 1985 |
Masters CL, Siinins G, Weinman NA, Beyreuther K. AMYLOID PLAQUE CORE PROTEIN IN ALZHEIMERʼS DISEASE AND AGED DOWNʼS SYNDROME Journal of Neuropathology and Experimental Neurology. 44: 363. DOI: 10.1097/00005072-198505000-00178 |
0.523 |
|
| 1985 |
Masters C, Multhaup G, Simms G, Pottgiesser J, Martins R, Beyreuther K. Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels. The Embo Journal. 4: 2757-2763. DOI: 10.1002/J.1460-2075.1985.Tb04000.X |
0.623 |
|
| 1985 |
Multhaup G, Diringer H, Hilmert H, Prinz H, Heukeshoven J, Beyreuther K. The protein component of scrapie-associated fibrils is a glycosylated low molecular weight protein. The Embo Journal. 4: 1495-1501. DOI: 10.1002/J.1460-2075.1985.Tb03808.X |
0.367 |
|
| 1981 |
Meyer TF, Beyreuther K, Geider K. Recognition of two initiation codons for the synthesis of phage fd gene 2 protein. Molecular & General Genetics : Mgg. 180: 489-94. PMID 7007816 DOI: 10.1007/Bf00268051 |
0.321 |
|
| 1973 |
Rao DR, Beyreuther K, Jaenicke L. A comparative study of pig and sheep-brain glutamine synthetases: tryptic peptides and thiol groups. European Journal of Biochemistry / Febs. 35: 582-92. PMID 4147201 DOI: 10.1111/J.1432-1033.1973.Tb02876.X |
0.301 |
|
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