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Matthew P. Frosch, MD PhD - Publications

Affiliations: 
Pathology Massachusetts General Hospital and Harvard University, Boston, MA, United States 
Area:
cerebral amyloid angiopathy
Website:
http://hst.mit.edu/public/people/faculty/facultyBiosketch.jsp?key=Frosch

212/417 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Greenberg ABW, Mekbib KY, Mehta NH, Kiziltug E, Duy PQ, Smith HR, Junkkari A, Leinonen V, Hyman BT, Chan D, Curry WT, Arnold SE, Barker Ii FG, Frosch MP, Kahle KT. Utility of cortical tissue analysis in normal pressure hydrocephalus. Cerebral Cortex (New York, N.Y. : 1991). PMID 38275188 DOI: 10.1093/cercor/bhae001  0.377
2023 Greenberg ABW, Mehta NH, Mekbib KY, Kiziltug E, Smith HR, Hyman BT, Chan D, Curry WT, Arnold SE, Frosch MP, Duy PQ, Kahle KT. Cases of familial idiopathic normal pressure hydrocephalus implicate genetic factors in disease pathogenesis. Cerebral Cortex (New York, N.Y. : 1991). PMID 37814356 DOI: 10.1093/cercor/bhad374  0.365
2023 Mate de Gerando A, Quittot N, Frosch MP, Hyman BT. Reply: Soluble oligomers or insoluble fibrils? Acta Neuropathologica. 146: 863-866. PMID 37733036 DOI: 10.1007/s00401-023-02634-5  0.34
2023 Sepulveda-Falla D, Villegas Lanau CA, White C, Serrano GE, Acosta-Uribe J, Mejía-Cupajita B, Villalba-Moreno ND, Lu P, Glatzel M, Kofler JK, Ghetti B, Frosch MP, Lopera Restrepo F, Kosik KS, Beach TG. Comorbidities in Early-Onset Sporadic versus Presenilin-1 Mutation-Associated Alzheimer's Disease Dementia: Evidence for Dependency on Alzheimer's Disease Neuropathological Changes. Medrxiv : the Preprint Server For Health Sciences. PMID 37646002 DOI: 10.1101/2023.08.14.23294081  0.306
2023 Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, ... ... Frosch MP, et al. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies and nominates ancestry-specific loci , , and as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. Medrxiv : the Preprint Server For Health Sciences. PMID 37461624 DOI: 10.1101/2023.07.06.23292311  0.399
2023 Gazula H, Tregidgo HFJ, Billot B, Balbastre Y, William-Ramirez J, Herisse R, Casamitjana A, Melief EJ, Latimer CS, Kilgore MD, Montine M, Robinson E, Blackburn E, Marshall MS, Connors TR, ... ... Frosch MP, et al. 3D analysis of dissection photographs with surface scanning and machine learning for quantitative neuropathology. Biorxiv : the Preprint Server For Biology. PMID 37333251 DOI: 10.1101/2023.06.08.544050  0.691
2023 Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, ... ... Frosch MP, et al. Creating the Pick's disease International Consortium: Association study of H2 haplotype with risk of Pick's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 37163045 DOI: 10.1101/2023.04.17.23288471  0.687
2023 Merrihew GE, Park J, Plubell D, Searle BC, Keene CD, Larson EB, Bateman R, Perrin RJ, Chhatwal JP, Farlow MR, McLean CA, Ghetti B, Newell KL, Frosch MP, Montine TJ, et al. A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer's disease. Scientific Data. 10: 206. PMID 37059743 DOI: 10.1038/s41597-023-02057-7  0.308
2023 Kivisäkk P, Carlyle BC, Sweeney T, Trombetta BA, LaCasse K, El-Mufti L, Tuncali I, Chibnik LB, Das S, Scherzer CR, Johnson KA, Dickerson BC, Gomez-Isla T, Blacker D, Oakley DH, ... Frosch MP, et al. Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment. Frontiers in Neurology. 14: 1069411. PMID 36937522 DOI: 10.3389/fneur.2023.1069411  0.717
2022 Dickson JR, Frosch MP, Hyman BT. Altered localization of nucleoporin 98 in primary tauopathies. Brain Communications. 5: fcac334. PMID 36601621 DOI: 10.1093/braincomms/fcac334  0.443
2022 Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, ... ... Frosch MP, et al. Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping. Cerebellum (London, England). PMID 36456723 DOI: 10.1007/s12311-022-01501-5  0.625
2022 Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, ... ... Frosch MP, et al. Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping. Cerebellum (London, England). PMID 36190676 DOI: 10.1007/s12311-022-01471-8  0.679
2022 Miller MB, Huang AY, Kim J, Zhou Z, Kirkham SL, Maury EA, Ziegenfuss JS, Reed HC, Neil JE, Rento L, Ryu SC, Ma CC, Luquette LJ, Ames HM, Oakley DH, ... Frosch MP, et al. Somatic genomic changes in single Alzheimer's disease neurons. Nature. PMID 35444284 DOI: 10.1038/s41586-022-04640-1  0.73
2022 Scherlek AA, Kozberg MG, Nicoll JAR, Perosa V, Freeze WM, van der Weerd L, Bacskai BJ, Greenberg SM, Frosch MP, Boche D, van Veluw SJ. Histopathological correlates of haemorrhagic lesions on magnetic resonance imaging in immunized Alzheimer's disease cases. Brain Communications. 4: fcac021. PMID 35224489 DOI: 10.1093/braincomms/fcac021  0.302
2022 Muñoz-Castro C, Noori A, Magdamo CG, Li Z, Marks JD, Frosch MP, Das S, Hyman BT, Serrano-Pozo A. Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer's disease. Journal of Neuroinflammation. 19: 30. PMID 35109872 DOI: 10.1186/s12974-022-02383-4  0.456
2021 Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Frosch MP, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z  0.479
2021 Fernandes AR, Dujardin S, Maté de Gérando A, Hyman BT, Frosch MP. Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds. Journal of Neuropathology and Experimental Neurology. PMID 34498073 DOI: 10.1093/jnen/nlab087  0.422
2021 Rodriguez S, Sahin A, Schrank BR, Al-Lawati H, Costantino I, Benz E, Fard D, Albers AD, Cao L, Gomez AC, Evans K, Ratti E, Cudkowicz M, Frosch MP, Talkowski M, et al. Genome-encoded cytoplasmic double-stranded RNAs, found in ALS-FTD brain, propagate neuronal loss. Science Translational Medicine. 13. PMID 34233951 DOI: 10.1126/scitranslmed.aaz4699  0.364
2021 Kamath TV, Klickstein N, Commins C, Fernandes AR, Oakley DH, Frosch MP, Hyman BT, Dujardin S. Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer's cases. Brain Communications. 3: fcab096. PMID 34222869 DOI: 10.1093/braincomms/fcab096  0.73
2021 Dickson JR, Yoon H, Frosch MP, Hyman BT. Cytoplasmic Mislocalization of RNA Polymerase II Subunit RPB1 in Alzheimer Disease Is Linked to Pathologic Tau. Journal of Neuropathology and Experimental Neurology. PMID 33990839 DOI: 10.1093/jnen/nlab040  0.487
2021 Oakley DH, Klickstein N, Commins C, Chung M, Dujardin S, Bennett RE, Hyman BT, Frosch MP. Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33893219 DOI: 10.1523/JNEUROSCI.2590-20.2021  0.723
2021 William CM, Stern MA, Pei X, Saqran L, Ramani M, Frosch MP, Hyman BT. Impairment of visual cortical plasticity by amyloid-beta species. Neurobiology of Disease. 154: 105344. PMID 33766652 DOI: 10.1016/j.nbd.2021.105344  0.443
2021 Mathewson ND, Ashenberg O, Tirosh I, Gritsch S, Perez EM, Marx S, Jerby-Arnon L, Chanoch-Myers R, Hara T, Richman AR, Ito Y, Pyrdol J, Friedrich M, Schumann K, Poitras MJ, ... ... Frosch MP, et al. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell. PMID 33592174 DOI: 10.1016/j.cell.2021.01.022  0.368
2021 Dujardin S, Commins C, Lathuiliere A, Beerepoot P, Fernandes AR, Kamath TV, De Los Santos MB, Klickstein N, Corjuc DL, Corjuc BT, Dooley PM, Viode A, Oakley DH, Moore BD, Mullin K, ... ... Frosch MP, et al. Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease. Nature Medicine. PMID 33514949 DOI: 10.1038/s41591-021-01251-7  0.729
2020 Clement NF, DeWitt JC, Frosch MP, Martinez-Lage M, Samore WR, Hedley-Whyte ET. A Simplified Brain Blocking Protocol Optimized for the Diagnosis of Neurodegenerative Disease Saves Time and Money While Preserving Anatomic Relationships. Archives of Pathology & Laboratory Medicine. PMID 33290509 DOI: 10.5858/arpa.2020-0322-OA  0.493
2020 Bryant AG, Hu M, Carlyle BC, Arnold SE, Frosch MP, Das S, Hyman BT, Bennett RE. Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. Frontiers in Neurology. 11: 575953. PMID 33041998 DOI: 10.3389/Fneur.2020.575953  0.526
2020 Asher DM, Belay E, Bigio E, Brandner S, Brubaker SA, Caughey B, Clark B, Damon I, Diamond M, Freund M, Hyman BT, Jucker M, Keene CD, Lieberman AP, Mackiewicz M, ... ... Frosch MP, et al. Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns. Journal of Neuropathology and Experimental Neurology. PMID 33000167 DOI: 10.1093/jnen/nlaa109  0.378
2020 Charidimou A, Perosa V, Frosch MP, Scherlek AA, Greenberg SM, van Veluw SJ. Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy. Brain : a Journal of Neurology. PMID 32935842 DOI: 10.1093/Brain/Awaa266  0.338
2020 Mueller C, Berry JD, McKenna-Yasek DM, Gernoux G, Owegi MA, Pothier LM, Douthwright CL, Gelevski D, Luppino SD, Blackwood M, Wightman NS, Oakley DH, Frosch MP, Flotte TR, Cudkowicz ME, et al. Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS. The New England Journal of Medicine. 383: 151-158. PMID 32640133 DOI: 10.1056/Nejmoa2005056  0.636
2020 Dujardin S, Commins C, Lathuiliere A, Beerepoot P, Fernandes AR, Kamath TV, De Los Santos MB, Klickstein N, Corjuc DL, Corjuc BT, Dooley PM, Viode A, Oakley DH, Moore BD, Mullin K, ... ... Frosch MP, et al. Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease. Nature Medicine. PMID 32572268 DOI: 10.1038/S41591-020-0938-9  0.763
2020 Regenhardt RW, Thon JM, Das AS, Thon OR, Charidimou A, Viswanathan A, Gurol ME, Chwalisz BK, Frosch MP, Cho TA, Greenberg SM. Association Between Immunosuppressive Treatment and Outcomes of Cerebral Amyloid Angiopathy-Related Inflammation. Jama Neurology. PMID 32568365 DOI: 10.1001/Jamaneurol.2020.1782  0.332
2020 Oakley DH, Chung M, Klickstein N, Commins C, Hyman BT, Frosch MP. The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue. Journal of Neuropathology and Experimental Neurology. PMID 32388561 DOI: 10.1093/Jnen/Nlaa025  0.757
2020 Kozberg MG, van Veluw SJ, Frosch MP, Greenberg SM. Hereditary cerebral amyloid angiopathy, Piedmont-type mutation. Neurology. Genetics. 6: e411. PMID 32337337 DOI: 10.1212/Nxg.0000000000000411  0.347
2020 Reiman EM, Arboleda-Velasquez JF, Quiroz YT, Huentelman MJ, Beach TG, Caselli RJ, Chen Y, Su Y, Myers AJ, Hardy J, Paul Vonsattel J, Younkin SG, Bennett DA, De Jager PL, Larson EB, ... ... Frosch MP, et al. Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study. Nature Communications. 11: 667. PMID 32015339 DOI: 10.1038/S41467-019-14279-8  0.517
2020 van Veluw SJ, Frosch MP, Scherlek AA, Lee D, Greenberg SM, Bacskai BJ. In vivo characterization of spontaneous microhemorrhage formation in mice with cerebral amyloid angiopathy. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19899377. PMID 31987010 DOI: 10.1177/0271678X19899377  0.324
2019 Corbett GT, Wang Z, Hong W, Colom-Cadena M, Rose J, Liao M, Asfaw A, Hall TC, Ding L, DeSousa A, Frosch MP, Collinge J, Harris DA, Perkinton MS, Spires-Jones TL, et al. PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins. Acta Neuropathologica. PMID 31853635 DOI: 10.1007/S00401-019-02114-9  0.393
2019 van Veluw SJ, Hou SS, Calvo-Rodriguez M, Arbel-Ornath M, Snyder AC, Frosch MP, Greenberg SM, Bacskai BJ. Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain. Neuron. PMID 31810839 DOI: 10.1016/J.Neuron.2019.10.033  0.396
2019 Marquié M, Agüero C, Amaral AC, Villarejo-Galende A, Ramanan P, Chong MST, Sáez-Calveras N, Bennett RE, Verwer EE, Kim SJW, Dhaynaut M, Alvarez VE, Johnson KA, McKee AC, Frosch MP, et al. [F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series. Acta Neuropathologica Communications. 7: 164. PMID 31661038 DOI: 10.1186/S40478-019-0808-1  0.365
2019 Charidimou A, Frosch MP, Salman RA, Baron JC, Cordonnier C, Hernandez-Guillamon M, Linn J, Raposo N, Rodrigues M, Romero JR, Schneider JA, Schreiber S, Smith EE, van Buchem MA, Viswanathan A, et al. Advancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0. International Journal of Stroke : Official Journal of the International Stroke Society. 1747493019855888. PMID 31514686 DOI: 10.1177/1747493019855888  0.354
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Frosch MP, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.415
2019 Hwang J, Bank AM, Mortazavi F, Oakley DH, Frosch MP, Schmahmann JD. Spinal cord α-synuclein deposition associated with myoclonus in patients with MSA-C. Neurology. 93: 302-309. PMID 31405935 DOI: 10.1212/Wnl.0000000000007949  0.65
2019 Zott B, Simon MM, Hong W, Unger F, Chen-Engerer HJ, Frosch MP, Sakmann B, Walsh DM, Konnerth A. A vicious cycle of β amyloid-dependent neuronal hyperactivation. Science (New York, N.Y.). 365: 559-565. PMID 31395777 DOI: 10.1126/Science.Aay0198  0.389
2019 Wong B, Lucente DE, MacLean J, Padmanabhan J, Quimby M, Brandt KD, Putcha D, Sherman J, Frosch MP, McGinnis S, Dickerson BC. Diagnostic evaluation and monitoring of patients with posterior cortical atrophy. Neurodegenerative Disease Management. PMID 31392920 DOI: 10.2217/Nmt-2018-0052  0.335
2019 Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, ... ... Frosch MP, et al. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. PMID 31327527 DOI: 10.1016/J.Cell.2019.06.024  0.447
2019 Gomez-Isla T, Frosch MP. The Challenge of Defining Alzheimer Disease Based on Biomarkers in the Absence of Symptoms. Jama Neurology. PMID 31305888 DOI: 10.1001/Jamaneurol.2019.1667  0.333
2019 Shirvan J, Clement N, Ye R, Katz S, Schultz A, Johnson KA, Gomez-Isla T, Frosch M, Growdon JH, Gomperts SN. Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease. Neurology. PMID 31243072 DOI: 10.1212/Wnl.0000000000007855  0.313
2019 Pasi M, Pongpitakmetha T, Charidimou A, Singh SD, Tsai HH, Xiong L, Boulouis G, Warren AD, Rosand J, Frosch MP, Viswanathan A, Gurol ME, Greenberg SM. Cerebellar Microbleed Distribution Patterns and Cerebral Amyloid Angiopathy. Stroke. STROKEAHA119024843. PMID 31159702 DOI: 10.1161/Strokeaha.119.024843  0.331
2019 van Veluw SJ, Scherlek AA, Freeze WM, Ter Telgte A, van der Kouwe AJ, Bacskai BJ, Frosch MP, Greenberg SM. Different microvascular alterations underlie microbleeds and microinfarcts. Annals of Neurology. PMID 31152566 DOI: 10.1002/Ana.25512  0.348
2019 Brinkmalm G, Hong W, Wang Z, Liu W, O'Malley TT, Sun X, Frosch MP, Selkoe DJ, Portelius E, Zetterberg H, Blennow K, Walsh DM. Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's brain. Brain : a Journal of Neurology. 142: 1441-1457. PMID 31032851 DOI: 10.1093/Brain/Awz066  0.396
2019 Aguero C, Dhaynaut M, Normandin MD, Amaral AC, Guehl NJ, Neelamegam R, Marquie M, Johnson KA, El Fakhri G, Frosch MP, Gomez-Isla T. Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue. Acta Neuropathologica Communications. 7: 37. PMID 30857558 DOI: 10.1186/S40478-019-0686-6  0.349
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Frosch MP, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.416
2019 van Veluw SJ, Reijmer YD, van der Kouwe AJ, Charidimou A, Riley GA, Leemans A, Bacskai BJ, Frosch MP, Viswanathan A, Greenberg SM. Histopathology of diffusion imaging abnormalities in cerebral amyloid angiopathy. Neurology. PMID 30700595 DOI: 10.1212/Wnl.0000000000007005  0.306
2019 Freeze WM, Bacskai BJ, Frosch MP, Jacobs HIL, Backes WH, Greenberg SM, van Veluw SJ. Blood-Brain Barrier Leakage and Microvascular Lesions in Cerebral Amyloid Angiopathy. Stroke. STROKEAHA118023788. PMID 30661497 DOI: 10.1161/Strokeaha.118.023788  0.356
2019 Pasi M, Charidimou A, Boulouis G, Fotiadis P, Morotti A, Xiong L, Marini S, Ayres A, Frosch MP, Goldstein JN, Rosand J, Gurol ME, Greenberg SM, Viswanathan A. Cerebral small vessel disease in patients with spontaneous cerebellar hemorrhage. Journal of Neurology. PMID 30617995 DOI: 10.1007/S00415-018-09177-W  0.327
2019 Thon JM, Regenhardt RW, Thon OR, Charidimou A, Viswanathan A, Gurol ME, Chwalisz BK, Frosch M, Cho TA, Greenberg SM. Abstract WP426: Cerebral Amyloid Angiopathy-related Inflammation: Immunosuppressive Treatment and Outcome Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.Wp426  0.327
2018 Dujardin S, Bégard S, Caillierez R, Lachaud C, Carrier S, Lieger S, Gonzalez JA, Deramecourt V, Déglon N, Maurage CA, Frosch MP, Hyman BT, Colin M, Buée L. Different tau species lead to heterogeneous tau pathology propagation and misfolding. Acta Neuropathologica Communications. 6: 132. PMID 30497516 DOI: 10.1186/S40478-018-0637-7  0.537
2018 Bale TA, Jordan JT, Rapalino O, Ramamurthy N, Jessop N, DeWitt JC, Nardi V, Martinez-Lage Alvarez M, Frosch M, Batchelor TT, Louis DN, Iafrate AJ, Cahill DP, Lennerz JK. Financially Effective Test-Algorithm to Identify an Aggressive, EGFR-amplified Variant of IDH-Wildtype, Lower-Grade Diffuse Glioma. Neuro-Oncology. PMID 30496526 DOI: 10.1093/Neuonc/Noy201  0.437
2018 Frosch MP. "When sex influences the brain: implications for Alzheimer disease". Acta Neuropathologica. PMID 30443762 DOI: 10.1007/S00401-018-1931-Y  0.373
2018 Barroeta-Espar I, Weinstock LD, Perez-Nievas BG, Meltzer AC, Tick-Chong MS, Amaral AC, Murray ME, Moulder KL, Morris JC, Cairns NJ, Parisi JE, Lowe VJ, Petersen RC, Kofler J, Ikonomovic MD, ... ... Frosch MP, et al. Distinct cytokine profiles in human brains resilient to Alzheimer's pathology. Neurobiology of Disease. PMID 30336198 DOI: 10.1016/J.Nbd.2018.10.009  0.408
2018 Ly KI, Oakley DH, Pine AB, Frosch MP, Chiou SH, Betensky RA, Pomerantz SR, Hochberg FH, Batchelor TT, Cahill DP, Dietrich J. Wide Range of Clinical Outcomes in Patients with Gliomatosis Cerebri Growth Pattern: A Clinical, Radiographic, and Histopathologic Study. The Oncologist. PMID 30097523 DOI: 10.1634/Theoncologist.2018-0086  0.665
2018 Jin M, O'Nuallain B, Hong W, Boyd J, Lagomarsino VN, O'Malley TT, Liu W, Vanderburg CR, Frosch MP, Young-Pearse T, Selkoe DJ, Walsh DM. An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer's disease. Nature Communications. 9: 2676. PMID 29992960 DOI: 10.1038/S41467-018-05068-W  0.414
2018 DeVos SL, Corjuc BT, Oakley DH, Nobuhara CK, Bannon RN, Chase A, Commins C, Gonzalez JA, Dooley PM, Frosch MP, Hyman BT. Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain. Frontiers in Neuroscience. 12: 267. PMID 29740275 DOI: 10.3389/Fnins.2018.00267  0.759
2018 DeVos SL, Corjuc BT, Commins C, Dujardin S, Bannon RN, Corjuc D, Moore BD, Bennett RE, Jorfi M, Gonzales JA, Dooley PM, Roe AD, Pitstick R, Irimia D, Frosch MP, et al. Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo. Brain : a Journal of Neurology. PMID 29733334 DOI: 10.1093/Brain/Awy117  0.531
2018 Hong W, Wang Z, Liu W, O'Malley TT, Jin M, Willem M, Haass C, Frosch MP, Walsh DM. Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer's disease brain. Acta Neuropathologica. PMID 29687257 DOI: 10.1007/S00401-018-1846-7  0.41
2018 Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, ... ... Frosch MP, et al. Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science (New York, N.Y.). 360: 331-335. PMID 29674595 DOI: 10.1126/Science.Aao4750  0.461
2017 Colom-Cadena M, Pegueroles J, Herrmann AG, Henstridge CM, Muñoz L, Querol-Vilaseca M, Martín-Paniello CS, Luque-Cabecerans J, Clarimon J, Belbin O, Núñez-Llaves R, Blesa R, Smith C, McKenzie CA, Frosch MP, et al. Synaptic phosphorylated α-synuclein in dementia with Lewy bodies. Brain : a Journal of Neurology. 140: 3204-3214. PMID 29177427 DOI: 10.1093/Brain/Awx275  0.466
2017 Wang Z, Jackson RJ, Hong W, Taylor WM, Corbett GT, Moreno A, Liu W, Li S, Frosch MP, Slutsky I, Young-Pearse T, Spires-Jones TL, Walsh DM. Human brain-derived Aβ oligomers bind to synapses and disrupt synaptic activity in a manner that requires APP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29101243 DOI: 10.1523/Jneurosci.2009-17.2017  0.39
2017 Marquié M, Verwer EE, Meltzer AC, Kim SJW, Agüero C, Gonzalez J, Makaretz SJ, Siao Tick Chong M, Ramanan P, Amaral AC, Normandin MD, Vanderburg CR, Gomperts SN, Johnson KA, Frosch MP, et al. Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson's case. Acta Neuropathologica Communications. 5: 75. PMID 29047416 DOI: 10.1186/S40478-017-0482-0  0.338
2017 DeWitt JC, Jordan JT, Frosch MP, Samore WR, Iafrate AJ, Louis DN, Lennerz JK. Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations. Neuro-Oncology. PMID 29016871 DOI: 10.1093/Neuonc/Nox120  0.464
2017 William CM, Saqran L, Stern MA, Chiang CL, Herrick S, Rangwala A, Albers MW, Frosch MP, Hyman BT. Activity-dependent dysfunction in visual and olfactory sensory systems in mouse models of Down syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28899917 DOI: 10.1523/Jneurosci.1045-17.2017  0.43
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Frosch MP, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.472
2017 Marquié M, Siao Tick Chong M, Antón-Fernández A, Verwer EE, Sáez-Calveras N, Meltzer AC, Ramanan P, Amaral AC, Gonzalez J, Normandin MD, Frosch MP, Gómez-Isla T. [F-18]-AV-1451 binding correlates with postmortem neurofibrillary tangle Braak staging. Acta Neuropathologica. PMID 28612291 DOI: 10.1007/S00401-017-1740-8  0.383
2017 Bennett RE, DeVos SL, Dujardin S, Corjuc B, Gor R, Gonzalez J, Roe AD, Frosch MP, Pitstick R, Carlson GA, Hyman BT. Enhanced Tau Aggregation in the Presence of Amyloid β. The American Journal of Pathology. PMID 28500862 DOI: 10.1016/J.Ajpath.2017.03.011  0.535
2017 Nobuhara CK, DeVos SL, Commins C, Wegmann S, Moore BD, Roe AD, Costantino I, Frosch MP, Pitstick R, Carlson GA, Hock C, Nitsch RM, Montrasio F, Grimm J, Cheung AE, et al. Tau Antibody-Targeting Pathological Species Block Neuronal Uptake and Interneuron Propagation of Tau in Vitro. The American Journal of Pathology. PMID 28408124 DOI: 10.1016/J.Ajpath.2017.01.022  0.515
2017 Williams EA, McGuone D, Frosch MP, Hyman BT, Laver N, Stemmer-Rachamimov A. Absence of Alzheimer Disease Neuropathologic Changes in Eyes of Subjects With Alzheimer Disease. Journal of Neuropathology and Experimental Neurology. PMID 28379416 DOI: 10.1093/Jnen/Nlx020  0.552
2017 Frosch MP. Tau aggregates: Where, When, Why and What consequences? Neuropathology and Applied Neurobiology. PMID 28370398 DOI: 10.1111/Nan.12400  0.408
2017 Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, ... ... Frosch MP, et al. Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq. Science (New York, N.Y.). 355. PMID 28360267 DOI: 10.1126/Science.Aai8478  0.447
2017 Charidimou A, Boulouis G, Gurol ME, Ayata C, Bacskai BJ, Frosch MP, Viswanathan A, Greenberg SM. Emerging concepts in sporadic cerebral amyloid angiopathy. Brain : a Journal of Neurology. PMID 28334869 DOI: 10.1093/Brain/Awx047  0.4
2017 Veluw SJv, Kouwe AJvd, Reijmer YD, Charidimou A, Viswanathan A, Frosch MP, Greenberg SM. Mri-Histopathology Associations Of Microbleeds And Microinfarcts In Intact Ex Vivo Hemispheres Of Patients With Cerebral Amyloid Angiopathy Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.716  0.343
2016 Marquié M, Normandin MD, Meltzer AC, Siao Tick Chong M, Andrea NV, Antón-Fernández A, Klunk WE, Mathis CA, Ikonomovic MD, Debnath M, Bien EA, Vanderburg CR, Costantino I, Makaretz S, DeVos SL, ... ... Frosch MP, et al. Pathologic correlations of [F-18]-AV-1451 imaging in non-Alzheimer tauopathies. Annals of Neurology. PMID 27997036 DOI: 10.1002/Ana.24844  0.739
2016 Troncone L, Luciani M, Coggins M, Wilker EH, Ho CY, Codispoti KE, Frosch MP, Kayed R, Del Monte F. Aβ Amyloid Pathology Affects the Hearts of Patients With Alzheimer's Disease: Mind the Heart. Journal of the American College of Cardiology. 68: 2395-2407. PMID 27908343 DOI: 10.1016/J.Jacc.2016.08.073  0.377
2016 Sellal F, Wallon D, Martinez-Almoyna L, Marelli C, Dhar A, Oesterlé H, Rovelet-Lecrux A, Rousseau S, Kourkoulis CE, Rosand J, DiPucchio ZY, Frosch M, Gombert C, Audoin B, Mine M, et al. APP Mutations in Cerebral Amyloid Angiopathy with or without Cortical Calcifications: Report of Three Families and a Literature Review. Journal of Alzheimer's Disease : Jad. PMID 27858710 DOI: 10.3233/Jad-160709  0.393
2016 Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, ... ... Frosch MP, et al. Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma. Nature. PMID 27806376 DOI: 10.1038/Nature20123  0.457
2016 van Veluw SJ, Kuijf HJ, Charidimou A, Viswanathan A, Biessels GJ, Rozemuller AJ, Frosch MP, Greenberg SM. Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy. Acta Neuropathologica. PMID 27771772 DOI: 10.1007/S00401-016-1635-0  0.366
2016 Liu J, Costantino I, Venugopalan N, Fischetti RF, Hyman BT, Frosch MP, Gomez-Isla T, Makowski L. Amyloid structure exhibits polymorphism on multiple length scales in human brain tissue. Scientific Reports. 6: 33079. PMID 27629394 DOI: 10.1038/Srep33079  0.519
2016 Lauer A, van Veluw SJ, William CM, Charidimou A, Roongpiboonsopit D, Vashkevich A, Ayres A, Martinez-Ramirez S, Gurol EM, Biessels GJ, Frosch M, Greenberg SM, Viswanathan A. Microbleeds on MRI are associated with microinfarcts on autopsy in cerebral amyloid angiopathy. Neurology. PMID 27613583 DOI: 10.1212/Wnl.0000000000003184  0.347
2016 Chang J, Arani K, Chew S, Frosch MP, Gonzalez RG, Maza N, Romero JM. Susceptibility Etching on MRI in Patients with Microangiopathy. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 27539492 DOI: 10.1111/Jon.12384  0.307
2016 Charidimou A, Martinez-Ramirez S, Reijmer YD, Oliveira-Filho J, Lauer A, Roongpiboonsopit D, Frosch M, Vashkevich A, Ayres A, Rosand J, Gurol ME, Greenberg SM, Viswanathan A. Total Magnetic Resonance Imaging Burden of Small Vessel Disease in Cerebral Amyloid Angiopathy: An Imaging-Pathologic Study of Concept Validation. Jama Neurology. PMID 27366898 DOI: 10.1001/Jamaneurol.2016.0832  0.341
2016 Takeda S, Commins C, DeVos SL, Nobuhara CK, Wegmann S, Roe AD, Costantino I, Fan Z, Nicholls SB, Sherman AE, Trisini Lipsanopoulos AT, Scherzer CR, Carlson GA, Pitstick R, Peskind ER, ... ... Frosch MP, et al. Seed-competent HMW tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients. Annals of Neurology. PMID 27351289 DOI: 10.1002/Ana.24716  0.552
2016 Rudinskiy N, Fuerer C, Demurtas D, Zamorano S, De Piano C, Herrmann A, Spires-Jones TL, Oeckl P, Otto M, Frosch MP, Moniatte M, Hyman BT, Schmid AW. Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27130892 DOI: 10.1016/J.Jalz.2016.03.011  0.519
2016 Serrano-Pozo A, Qian J, Muzikansky A, Monsell SE, Montine TJ, Frosch MP, Betensky RA, Hyman BT. Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum. Journal of Neuropathology and Experimental Neurology. PMID 27105663 DOI: 10.1093/Jnen/Nlw026  0.488
2016 Walker MA, Mohler KP, Hopkins KW, Oakley DH, Sweetser DA, Ibba M, Frosch MP, Thibert RL. Novel Compound Heterozygous Mutations Expand the Recognized Phenotypes of FARS2-Linked Disease. Journal of Child Neurology. PMID 27095821 DOI: 10.1177/0883073816643402  0.684
2016 Jin M, O'Malley TT, Boyd J, Liu W, Frosch MP, Walsh DM, Selkoe DJ. P4-058: A Novel Paradigm for the Identification and Targeting of Bioactive Abeta Species from Alzheimer Brain Alzheimer's & Dementia. 12: P1037-P1037. DOI: 10.1016/J.Jalz.2016.06.2148  0.336
2015 Auriel E, Charidimou A, Gurol ME, Ni J, Van Etten ES, Martinez-Ramirez S, Boulouis G, Piazza F, DiFrancesco JC, Frosch MP, Pontes-Neto OV, Shoamanesh A, Reijmer Y, Vashkevich A, Ayres AM, et al. Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. Jama Neurology. 1-6. PMID 26720093 DOI: 10.1001/Jamaneurol.2015.4078  0.371
2015 Serrano-Pozo A, Betensky RA, Frosch MP, Hyman BT. Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease. The American Journal of Pathology. PMID 26687817 DOI: 10.1016/J.Ajpath.2015.10.010  0.525
2015 Wood LB, Winslow AR, Proctor EA, McGuone D, Mordes DA, Frosch MP, Hyman BT, Lauffenburger DA, Haigis KM. Identification of neurotoxic cytokines by profiling Alzheimer's disease tissues and neuron culture viability screening. Scientific Reports. 5: 16622. PMID 26564777 DOI: 10.1038/Srep16622  0.522
2015 Takeda S, Wegmann S, Cho H, DeVos SL, Commins C, Roe AD, Nicholls SB, Carlson GA, Pitstick R, Nobuhara CK, Costantino I, Frosch MP, Müller DJ, Irimia D, Hyman BT. Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain. Nature Communications. 6: 8490. PMID 26458742 DOI: 10.1038/Ncomms9490  0.541
2015 Musolino PL, Gong Y, Snyder JM, Jimenez S, Lok J, Lo EH, Moser AB, Grabowski EF, Frosch MP, Eichler FS. Brain endothelial dysfunction in cerebral adrenoleukodystrophy. Brain : a Journal of Neurology. PMID 26377633 DOI: 10.1093/Brain/Awv250  0.3
2015 Marquié M, Normandin MD, Vanderburg CR, Costantino IM, Bien EA, Rycyna LG, Klunk WE, Mathis CA, Ikonomovic MD, Debnath ML, Vasdev N, Dickerson BC, Gomperts SN, Growdon JH, Johnson KA, ... Frosch MP, et al. Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue. Annals of Neurology. PMID 26344059 DOI: 10.1002/Ana.24517  0.46
2015 Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, et al. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26327235 DOI: 10.1016/J.Jalz.2015.07.492  0.508
2015 Zhao L, Arbel-Ornath M, Wang X, Betensky RA, Greenberg SM, Frosch MP, Bacskai BJ. Matrix metalloproteinase 9-mediated intracerebral hemorrhage induced by cerebral amyloid angiopathy. Neurobiology of Aging. PMID 26248866 DOI: 10.1016/J.Neurobiolaging.2015.07.016  0.313
2015 Mc Donald JM, O'Malley TT, Liu W, Mably AJ, Brinkmalm G, Portelius E, Wittbold WM, Frosch MP, Walsh DM. The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25846299 DOI: 10.1016/J.Jalz.2015.01.005  0.388
2015 Charidimou A, Martinez-Ramirez S, Shoamanesh A, Oliveira-Filho J, Frosch M, Vashkevich A, Ayres A, Rosand J, Gurol ME, Greenberg SM, Viswanathan A. Cerebral amyloid angiopathy with and without hemorrhage: evidence for different disease phenotypes. Neurology. 84: 1206-12. PMID 25716356 DOI: 10.1212/Wnl.0000000000001398  0.402
2015 Etherton MR, Neagu MR, Oakley DH, Koch MJ, Shin JH, Frosch MP, Berkowitz AL, Dietrich J. A 20-year-old man with back pain and lower extremity weakness. Jama Neurology. 72: 363-6. PMID 25621865 DOI: 10.1001/Jamaneurol.2014.3833  0.661
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Frosch MP, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.519
2015 Takeda S, Commins C, Wegmann S, Roe AD, Fan Z, DeVos SL, Costantino I, Trisini Lipsanopoulos A, Frosch MP, Hyman BT. P3-071: A unique high-molecular-weight tau species is involved in propagation and accumulates in the cerebrospinal fluid of Alzheimer's disease patients Alzheimer's & Dementia. 11: P644-P644. DOI: 10.1016/J.Jalz.2015.06.938  0.498
2014 Tai HC, Wang BY, Serrano-Pozo A, Frosch MP, Spires-Jones TL, Hyman BT. Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease. Acta Neuropathologica Communications. 2: 146. PMID 25330988 DOI: 10.1186/S40478-014-0146-2  0.524
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Frosch MP, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.466
2014 Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, ... ... Frosch MP, et al. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Plos Genetics. 10: e1004606. PMID 25188341 DOI: 10.1371/Journal.Pgen.1004606  0.534
2014 Lanthier S, Calabrese LH, Ferro JM, Putaala J, Strbian D, Chagnon M, Frosch MP, Singhal AB, Salvarani C, Létourneau-Guillon L, Poppe AY, Guilbert F, Raymond J, Muccilli A. The INTERnational Study on Primary Angiitis of the CEntral nervous system--a call to the world. International Journal of Stroke : Official Journal of the International Stroke Society. 9: E23. PMID 24909198 DOI: 10.1111/Ijs.12284  0.301
2014 Bit-Ivan EN, Suh E, Shim HS, Weintraub S, Hyman BT, Arnold SE, McCarty-Wood E, Van Deerlin VM, Schneider JA, Trojanowski JQ, Frosch MP, Baker MC, Rademakers R, Mesulam M, Bigio EH. A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases. Journal of Neuropathology and Experimental Neurology. 73: 467-73. PMID 24709683 DOI: 10.1097/Nen.0000000000000070  0.47
2014 Landau SM, Frosch MP. Tracking the earliest pathologic changes in Alzheimer disease. Neurology. 82: 1576-7. PMID 24706009 DOI: 10.1212/Wnl.0000000000000392  0.414
2014 Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gómez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BT. Mild to moderate Alzheimer dementia with insufficient neuropathological changes. Annals of Neurology. 75: 597-601. PMID 24585367 DOI: 10.1002/Ana.24125  0.521
2014 Annese J, Schenker-Ahmed NM, Bartsch H, Maechler P, Sheh C, Thomas N, Kayano J, Ghatan A, Bresler N, Frosch MP, Klaming R, Corkin S. Postmortem examination of patient H.M.'s brain based on histological sectioning and digital 3D reconstruction. Nature Communications. 5: 3122. PMID 24473151 DOI: 10.1038/Ncomms4122  0.306
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... Frosch MP, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  0.304
2013 Serrano-Pozo A, Qian J, Monsell SE, Frosch MP, Betensky RA, Hyman BT. Examination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center. Journal of Neuropathology and Experimental Neurology. 72: 1182-92. PMID 24226270 DOI: 10.1097/Nen.0000000000000016  0.534
2013 Perez-Nievas BG, Stein TD, Tai HC, Dols-Icardo O, Scotton TC, Barroeta-Espar I, Fernandez-Carballo L, de Munain EL, Perez J, Marquie M, Serrano-Pozo A, Frosch MP, Lowe V, Parisi JE, Petersen RC, et al. Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology. Brain : a Journal of Neurology. 136: 2510-26. PMID 23824488 DOI: 10.1093/Brain/Awt171  0.51
2013 Arbel-Ornath M, Hudry E, Eikermann-Haerter K, Hou S, Gregory JL, Zhao L, Betensky RA, Frosch MP, Greenberg SM, Bacskai BJ. Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer's disease mouse models. Acta Neuropathologica. 126: 353-64. PMID 23818064 DOI: 10.1007/S00401-013-1145-2  0.407
2013 Kay KR, Smith C, Wright AK, Serrano-Pozo A, Pooler AM, Koffie R, Bastin ME, Bak TH, Abrahams S, Kopeikina KJ, McGuone D, Frosch MP, Gillingwater TH, Hyman BT, Spires-Jones TL. Studying synapses in human brain with array tomography and electron microscopy. Nature Protocols. 8: 1366-80. PMID 23787894 DOI: 10.1038/Nprot.2013.078  0.45
2013 Serrano-Pozo A, Muzikansky A, Gómez-Isla T, Growdon JH, Betensky RA, Frosch MP, Hyman BT. Differential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 72: 462-71. PMID 23656989 DOI: 10.1097/Nen.0B013E3182933788  0.519
2013 Serrano-Pozo A, Gómez-Isla T, Growdon JH, Frosch MP, Hyman BT. A phenotypic change but not proliferation underlies glial responses in Alzheimer disease. The American Journal of Pathology. 182: 2332-44. PMID 23602650 DOI: 10.1016/J.Ajpath.2013.02.031  0.526
2013 McFarland NR, Burdett T, Desjardins CA, Frosch MP, Schwarzschild MA. Postmortem brain levels of urate and precursors in Parkinson's disease and related disorders. Neuro-Degenerative Diseases. 12: 189-98. PMID 23467193 DOI: 10.1159/000346370  0.364
2013 Augustinack JC, Huber KE, Stevens AA, Roy M, Frosch MP, van der Kouwe AJ, Wald LL, Van Leemput K, McKee AC, Fischl B. Predicting the location of human perirhinal cortex, Brodmann's area 35, from MRI. Neuroimage. 64: 32-42. PMID 22960087 DOI: 10.1016/J.Neuroimage.2012.08.071  0.315
2013 Horton LC, Frosch MP, Vangel MG, Weigel-DiFranco C, Berson EL, Schmahmann JD. Spinocerebellar ataxia type 7: clinical course, phenotype-genotype correlations, and neuropathology. Cerebellum (London, England). 12: 176-93. PMID 22915085 DOI: 10.1007/S12311-012-0412-4  0.313
2012 Hashimoto T, Serrano-Pozo A, Hori Y, Adams KW, Takeda S, Banerji AO, Mitani A, Joyner D, Thyssen DH, Bacskai BJ, Frosch MP, Spires-Jones TL, Finn MB, Holtzman DM, Hyman BT. Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15181-92. PMID 23100439 DOI: 10.1523/Jneurosci.1542-12.2012  0.532
2012 Gregory JL, Prada CM, Fine SJ, Garcia-Alloza M, Betensky RA, Arbel-Ornath M, Greenberg SM, Bacskai BJ, Frosch MP. Reducing available soluble β-amyloid prevents progression of cerebral amyloid angiopathy in transgenic mice. Journal of Neuropathology and Experimental Neurology. 71: 1009-17. PMID 23095848 DOI: 10.1097/Nen.0B013E3182729845  0.403
2012 Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed Whole Slide Image viewing system. Studies in Health Technology and Informatics. 179: 239-49. PMID 22925804 DOI: 10.3233/978-1-61499-086-4-239  0.369
2012 Tai HC, Serrano-Pozo A, Hashimoto T, Frosch MP, Spires-Jones TL, Hyman BT. The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system. The American Journal of Pathology. 181: 1426-35. PMID 22867711 DOI: 10.1016/J.Ajpath.2012.06.033  0.526
2012 Serrano-Pozo A, Mielke ML, Muzitansky A, Gómez-Isla T, Growdon JH, Bacskai BJ, Betensky RA, Frosch MP, Hyman BT. Stable size distribution of amyloid plaques over the course of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 71: 694-701. PMID 22805771 DOI: 10.1097/Nen.0B013E31825E77De  0.523
2012 Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Frosch M, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801  0.381
2012 William CM, Andermann ML, Goldey GJ, Roumis DK, Reid RC, Shatz CJ, Albers MW, Frosch MP, Hyman BT. Synaptic plasticity defect following visual deprivation in Alzheimer's disease model transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8004-11. PMID 22674275 DOI: 10.1523/JNEUROSCI.5369-11.2012  0.414
2012 Koffie RM, Hashimoto T, Tai HC, Kay KR, Serrano-Pozo A, Joyner D, Hou S, Kopeikina KJ, Frosch MP, Lee VM, Holtzman DM, Hyman BT, Spires-Jones TL. Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β. Brain : a Journal of Neurology. 135: 2155-68. PMID 22637583 DOI: 10.1093/Brain/Aws127  0.524
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Frosch MP, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161  0.402
2012 Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/Nen.0B013E31825018F7  0.519
2012 Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 1-13. PMID 22265587 DOI: 10.1016/J.Jalz.2011.10.007  0.554
2012 Augustinack JC, Huber KE, Postelnicu GM, Kakunoori S, Wang R, van der Kouwe AJ, Wald LL, Stein TD, Frosch MP, Fischl B. Entorhinal verrucae geometry is coincident and correlates with Alzheimer's lesions: a combined neuropathology and high-resolution ex vivo MRI analysis. Acta Neuropathologica. 123: 85-96. PMID 22160360 DOI: 10.1007/S00401-011-0929-5  0.376
2012 Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathologica. 123: 1-11. PMID 22101365 DOI: 10.1007/S00401-011-0910-3  0.546
2012 Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed whole slide image viewing system. Analytical Cellular Pathology (Amsterdam). 35: 65-73. PMID 22063731 DOI: 10.3233/Acp-2011-0042  0.442
2011 Serrano-Pozo A, Frosch MP, Masliah E, Hyman BT. Neuropathological alterations in Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 1: a006189. PMID 22229116 DOI: 10.1101/Cshperspect.A006189  0.554
2011 Garcia-Alloza M, Gregory J, Kuchibhotla KV, Fine S, Wei Y, Ayata C, Frosch MP, Greenberg SM, Bacskai BJ. Cerebrovascular lesions induce transient β-amyloid deposition. Brain : a Journal of Neurology. 134: 3697-707. PMID 22120142 DOI: 10.1093/Brain/Awr300  0.39
2011 Kopeikina KJ, Carlson GA, Pitstick R, Ludvigson AE, Peters A, Luebke JI, Koffie RM, Frosch MP, Hyman BT, Spires-Jones TL. Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain. The American Journal of Pathology. 179: 2071-82. PMID 21854751 DOI: 10.1016/J.Ajpath.2011.07.004  0.527
2011 Sperling RA, Jack CR, Black SE, Frosch MP, Greenberg SM, Hyman BT, Scheltens P, Carrillo MC, Thies W, Bednar MM, Black RS, Brashear HR, Grundman M, Siemers ER, Feldman HH, et al. Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 367-85. PMID 21784348 DOI: 10.1016/J.Jalz.2011.05.2351  0.524
2011 Serrano-Pozo A, Mielke ML, Gómez-Isla T, Betensky RA, Growdon JH, Frosch MP, Hyman BT. Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease. The American Journal of Pathology. 179: 1373-84. PMID 21777559 DOI: 10.1016/J.Ajpath.2011.05.047  0.55
2011 Arboleda-Velasquez JF, Manent J, Lee JH, Tikka S, Ospina C, Vanderburg CR, Frosch MP, Rodríguez-Falcón M, Villen J, Gygi S, Lopera F, Kalimo H, Moskowitz MA, Ayata C, Louvi A, et al. Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proceedings of the National Academy of Sciences of the United States of America. 108: E128-35. PMID 21555590 DOI: 10.1073/Pnas.1101964108  0.326
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Frosch MP, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801  0.406
2011 Greenberg SM, Frosch MP. Life imitates art: anti-amyloid antibodies and inflammatory cerebral amyloid angiopathy. Neurology. 76: 772-3. PMID 21357829 DOI: 10.1212/Wnl.0B013E31820E7Bce  0.37
2011 di Tomaso E, Snuderl M, Kamoun WS, Duda DG, Auluck PK, Fazlollahi L, Andronesi OC, Frosch MP, Wen PY, Plotkin SR, Hedley-Whyte ET, Sorensen AG, Batchelor TT, Jain RK. Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. Cancer Research. 71: 19-28. PMID 21199795 DOI: 10.1158/0008-5472.Can-10-2602  0.729
2011 Skoglund L, Matsui T, Freeman SH, Wallin A, Blom ES, Frosch MP, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser A. Novel progranulin mutation detected in 2 patients with FTLD. Alzheimer Disease and Associated Disorders. 25: 173-8. PMID 20975516 DOI: 10.1097/Wad.0B013E3181Fbc22C  0.425
2011 Rutgers KS, van Remoortere A, van Buchem MA, Verrips CT, Greenberg SM, Bacskai BJ, Frosch MP, van Duinen SG, Maat-Schieman ML, van der Maarel SM. Differential recognition of vascular and parenchymal beta amyloid deposition. Neurobiology of Aging. 32: 1774-83. PMID 20015576 DOI: 10.1016/J.Neurobiolaging.2009.11.012  0.304
2011 Holtzman D, Hyman B, Lee V, Spires-Jones T, Koffie R, Hashimoto T, Joyner D, Hou S, Kopeikina K, Frosch M. O1-05-01: APOE4 plays a role in Abeta-mediated synapse loss in Alzheimer's disease Alzheimer's & Dementia. 7: S103-S104. DOI: 10.1016/J.Jalz.2011.05.256  0.484
2010 Biffi A, Plourde A, Shen Y, Onofrio R, Smith EE, Frosch M, Prada CM, Gusella J, Greenberg SM, Rosand J. Screening for familial APP mutations in sporadic cerebral amyloid angiopathy. Plos One. 5: e13949. PMID 21085603 DOI: 10.1371/Journal.Pone.0013949  0.344
2010 Dierksen GA, Skehan ME, Khan MA, Jeng J, Nandigam RN, Becker JA, Kumar A, Neal KL, Betensky RA, Frosch MP, Rosand J, Johnson KA, Viswanathan A, Salat DH, Greenberg SM. Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy. Annals of Neurology. 68: 545-8. PMID 20865701 DOI: 10.1002/Ana.22099  0.357
2010 Lu Q, Ding K, Frosch MP, Jones S, Wolfe M, Xia W, Lanford GW. Alzheimer's disease-linked presenilin mutation (PS1M146L) induces filamin expression and γ-secretase independent redistribution. Journal of Alzheimer's Disease : Jad. 22: 235-45. PMID 20847418 DOI: 10.3233/Jad-2010-100585  0.348
2010 Smith EE, Nandigam KR, Chen YW, Jeng J, Salat D, Halpin A, Frosch M, Wendell L, Fazen L, Rosand J, Viswanathan A, Greenberg SM. MRI markers of small vessel disease in lobar and deep hemispheric intracerebral hemorrhage. Stroke; a Journal of Cerebral Circulation. 41: 1933-8. PMID 20689084 DOI: 10.1161/Strokeaha.110.579078  0.324
2010 Huttunen HJ, Havas D, Peach C, Barren C, Duller S, Xia W, Frosch MP, Hutter-Paier B, Windisch M, Kovacs DM. The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice. Journal of Neuropathology and Experimental Neurology. 69: 777-88. PMID 20613640 DOI: 10.1097/Nen.0B013E3181E77Ed9  0.373
2010 Nelson PT, Kukull WA, Frosch MP. Thinking outside the box: Alzheimer-type neuropathology that does not map directly onto current consensus recommendations. Journal of Neuropathology and Experimental Neurology. 69: 449-54. PMID 20418781 DOI: 10.1097/Nen.0B013E3181D8Db07  0.421
2010 Serrano-Pozo A, William CM, Ferrer I, Uro-Coste E, Delisle MB, Maurage CA, Hock C, Nitsch RM, Masliah E, Growdon JH, Frosch MP, Hyman BT. Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain : a Journal of Neurology. 133: 1312-27. PMID 20360050 DOI: 10.1093/Brain/Awq056  0.513
2010 Crittenden JR, Dunn DE, Merali FI, Woodman B, Yim M, Borkowska AE, Frosch MP, Bates GP, Housman DE, Lo DC, Graybiel AM. CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease. Human Molecular Genetics. 19: 1756-65. PMID 20147317 DOI: 10.1093/Hmg/Ddq055  0.353
2009 Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, et al. Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Archives of Pathology & Laboratory Medicine. 133: 1949-53. PMID 19961250 DOI: 10.1043/1543-2165-133.12.1949  0.466
2009 Skoglund L, Ingvast S, Matsui T, Freeman SH, Frosch MP, Brundin R, Giedraitis V, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser A. No evidence of PGRN or MAPT gene dosage alterations in a collection of patients with frontotemporal lobar degeneration. Dementia and Geriatric Cognitive Disorders. 28: 471-5. PMID 19940479 DOI: 10.1159/000260046  0.482
2009 Fischl B, Stevens AA, Rajendran N, Yeo BT, Greve DN, Van Leemput K, Polimeni JR, Kakunoori S, Buckner RL, Pacheco J, Salat DH, Melcher J, Frosch MP, Hyman BT, Grant PE, et al. Predicting the location of entorhinal cortex from MRI. Neuroimage. 47: 8-17. PMID 19376238 DOI: 10.1016/J.Neuroimage.2009.04.033  0.492
2009 Freeman SH, Hyman BT, Sims KB, Hedley-Whyte ET, Vossough A, Frosch MP, Schmahmann JD. Adult onset leukodystrophy with neuroaxonal spheroids: clinical, neuroimaging and neuropathologic observations. Brain Pathology (Zurich, Switzerland). 19: 39-47. PMID 18422757 DOI: 10.1111/J.1750-3639.2008.00163.X  0.611
2008 Greenberg SM, Grabowski T, Gurol ME, Skehan ME, Nandigam RN, Becker JA, Garcia-Alloza M, Prada C, Frosch MP, Rosand J, Viswanathan A, Smith EE, Johnson KA. Detection of isolated cerebrovascular beta-amyloid with Pittsburgh compound B. Annals of Neurology. 64: 587-91. PMID 19067370 DOI: 10.1002/Ana.21528  0.358
2008 Freeman SH, Kandel R, Cruz L, Rozkalne A, Newell K, Frosch MP, Hedley-Whyte ET, Locascio JJ, Lipsitz LA, Hyman BT. Preservation of neuronal number despite age-related cortical brain atrophy in elderly subjects without Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 67: 1205-12. PMID 19018241 DOI: 10.1097/Nen.0B013E31818Fc72F  0.635
2008 Freeman SH, Spires-Jones T, Hyman BT, Growdon JH, Frosch MP. TAR-DNA binding protein 43 in Pick disease. Journal of Neuropathology and Experimental Neurology. 67: 62-7. PMID 18091558 DOI: 10.1097/Nen.0B013E3181609361  0.506
2008 di Tomaso E, Frosch MP, Auluck PK, Cahill D, Duda DG, Plotkin SR, Loeffler JS, Sorensen AG, Batchelor TT, Jain RK. Characterization of blood vessels in brain autopsies of GBM patients who received antiangiogenic treatment Journal of Clinical Oncology. 26: 2009-2009. DOI: 10.1200/Jco.2008.26.15_Suppl.2009  0.675
2008 Johnson K, Grabowski T, Gurol M, Skehan M, Nandigam R, Becker J, Garcia-Alloza M, Prada C, Frosch M, Rosand J, Smith E, Greenberg S. P1-254: Early detection of hereditary cerebral amyloid angiopathy with Pittsburgh Compound B Alzheimer's & Dementia. 4: T290-T290. DOI: 10.1016/J.Jalz.2008.05.844  0.355
2008 Freeman S, Kandel R, Cruz L, Rozkalne A, Newell K, Frosch MP, Hedley-Whyte ET, Lipsitz L, Hyman BT. P4-154: Neuronal atrophy and neuropil loss, rather than neuronal loss, underlies age-related cortical brain atrophy in elderly subjects without Alzheimer's disease Alzheimer's & Dementia. 4: T715-T715. DOI: 10.1016/J.Jalz.2008.05.2221  0.486
2008 Prada CM, Garcia-Alloza M, Fine S, Betensky RA, Ebiana V, Greenber SM, Bacskai BJ, Frosch MP. P2-353: Reducing the availability of soluble Aβ halts progression of cerebral amyloid angiopathy in transgenic mice Alzheimer's & Dementia. 4: T476-T476. DOI: 10.1016/J.Jalz.2008.05.1431  0.349
2008 Kowa H, Matsui T, Bouzou B, Clark T, Freeman S, Frosch M, Hyman B. P2-194: Complement pathways are upregulated in angular gyrus of primary progressive aphasia cases Alzheimer's & Dementia. 4: T427-T428. DOI: 10.1016/J.Jalz.2008.05.1268  0.407
2007 Ingelsson M, Ramasamy K, Russ C, Freeman SH, Orne J, Raju S, Matsui T, Growdon JH, Frosch MP, Ghetti B, Brown RH, Irizarry MC, Hyman BT. Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains. Acta Neuropathologica. 114: 471-9. PMID 17721707 DOI: 10.1007/S00401-007-0280-Z  0.512
2007 Shin HK, Jones PB, Garcia-Alloza M, Borrelli L, Greenberg SM, Bacskai BJ, Frosch MP, Hyman BT, Moskowitz MA, Ayata C. Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy. Brain : a Journal of Neurology. 130: 2310-9. PMID 17638859 DOI: 10.1093/Brain/Awm156  0.489
2007 Matsui T, Ingelsson M, Fukumoto H, Ramasamy K, Kowa H, Frosch MP, Irizarry MC, Hyman BT. Expression of APP pathway mRNAs and proteins in Alzheimer's disease. Brain Research. 1161: 116-23. PMID 17586478 DOI: 10.1016/J.Brainres.2007.05.050  0.517
2007 Kinnecom C, Lev MH, Wendell L, Smith EE, Rosand J, Frosch MP, Greenberg SM. Course of cerebral amyloid angiopathy-related inflammation. Neurology. 68: 1411-6. PMID 17452586 DOI: 10.1212/01.Wnl.0000260066.98681.2E  0.323
2007 Freeman SH, Raju S, Hyman BT, Frosch MP, Irizarry MC. Plasma Abeta levels do not reflect brain Abeta levels. Journal of Neuropathology and Experimental Neurology. 66: 264-71. PMID 17413317 DOI: 10.1097/Nen.0B013E31803D3Ae4  0.494
2007 Bacskai BJ, Frosch MP, Freeman SH, Raymond SB, Augustinack JC, Johnson KA, Irizarry MC, Klunk WE, Mathis CA, Dekosky ST, Greenberg SM, Hyman BT, Growdon JH. Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. Archives of Neurology. 64: 431-4. PMID 17353389 DOI: 10.1001/Archneur.64.3.431  0.516
2007 Prada CM, Garcia-Alloza M, Betensky RA, Zhang-Nunes SX, Greenberg SM, Bacskai BJ, Frosch MP. Antibody-mediated clearance of amyloid-beta peptide from cerebral amyloid angiopathy revealed by quantitative in vivo imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1973-80. PMID 17314293 DOI: 10.1523/Jneurosci.5426-06.2007  0.392
2007 Frosch MP, Prada CM, Betensky RA, Garcia-Alloza M, Greenberg SM, Bacskai BJ. Effect of passive immunotherapy on the rate of progression of cerebral amyloid angiopathy (caa) in transgenic mice: 126.7 Journal of Neuropathology and Experimental Neurology. 66: 434-435. DOI: 10.1097/01.Jnen.0000268872.45065.C2  0.31
2007 Frosch MP, Prada CM, Betensky RA, Garcia-Alloza M, Greenberg SM, Bacskai BJ. Effect of passive immunotherapy on the rate of progression of cerebral amyloid angiopathy (caa) in transgenic mice Journal of Neuropathology and Experimental Neurology. 66: 434-435. DOI: 10.1096/Fasebj.21.5.A73-D  0.31
2006 Garcia-Alloza M, Robbins EM, Zhang-Nunes SX, Purcell SM, Betensky RA, Raju S, Prada C, Greenberg SM, Bacskai BJ, Frosch MP. Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease. Neurobiology of Disease. 24: 516-24. PMID 17029828 DOI: 10.1016/J.Nbd.2006.08.017  0.375
2006 Guo S, Wang S, Kim WJ, Lee SR, Frosch MP, Bacskai BJ, Greenberg SM, Lo EH. Effects of apoE isoforms on beta-amyloid-induced matrix metalloproteinase-9 in rat astrocytes. Brain Research. 1111: 222-6. PMID 16919608 DOI: 10.1016/J.Brainres.2006.06.041  0.333
2006 Ingelsson M, Ramasamy K, Cantuti-Castelvetri I, Skoglund L, Matsui T, Orne J, Kowa H, Raju S, Vanderburg CR, Augustinack JC, de Silva R, Lees AJ, Lannfelt L, Growdon JH, Frosch MP, et al. No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain. Acta Neuropathologica. 112: 439-49. PMID 16802167 DOI: 10.1007/S00401-006-0095-3  0.527
2006 Matsui T, Ramasamy K, Ingelsson M, Fukumoto H, Conrad C, Frosch MP, Irizarry MC, Yuan J, Hyman BT. Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels. Journal of Neuropathology and Experimental Neurology. 65: 508-15. PMID 16772874 DOI: 10.1097/01.Jnen.0000229238.05748.12  0.506
2006 Zhang-Nunes SX, Maat-Schieman ML, van Duinen SG, Roos RA, Frosch MP, Greenberg SM. The cerebral beta-amyloid angiopathies: hereditary and sporadic. Brain Pathology (Zurich, Switzerland). 16: 30-9. PMID 16612980 DOI: 10.1111/J.1750-3639.2006.Tb00559.X  0.37
2006 Klucken J, Ingelsson M, Shin Y, Irizarry MC, Hedley-Whyte ET, Frosch M, Growdon J, McLean P, Hyman BT. Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies. Acta Neuropathologica. 111: 101-8. PMID 16482476 DOI: 10.1007/S00401-005-0027-7  0.603
2006 Robbins EM, Betensky RA, Domnitz SB, Purcell SM, Garcia-Alloza M, Greenberg C, Rebeck GW, Hyman BT, Greenberg SM, Frosch MP, Bacskai BJ. Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 365-71. PMID 16407531 DOI: 10.1523/Jneurosci.3854-05.2006  0.525
2006 Freeze WM, Greenberg SM, Frosch MP, Jacobs HI, Backes WH, Bacskai B, van Veluw SJ. IC-P-051: BLOOD-BRAIN BARRIER LEAKAGE AND MICROVASCULAR LESIONS IN CEREBRAL AMYLOID ANGIOPATHY: A POSTMORTEM MRI AND HISTOPATHOLOGY STUDY Alzheimer's & Dementia. 14: P50-P50. DOI: 10.1016/J.Jalz.2018.06.1172  0.306
2006 Prada C, Betensky R, Garcia-Alloza M, Zhang-Nunes S, Greenberg SM, Bacskai BJ, Frosch MP. P4-292: Effect of immunotherapy on the rate of progression of cerebral amyloid angiopathy (CAA) in transgenic mice Alzheimer's & Dementia. 2: S602-S603. DOI: 10.1016/J.Jalz.2006.05.2031  0.309
2006 Matsui T, Ingelsson M, Fukumoto H, Ramasamy K, Kowa H, Frosch MP, Irizarry MC, Hyman BT. P4-079: Coordinated expression of APP pathway mRNA and protein in AD Alzheimer's & Dementia. 2: S537-S537. DOI: 10.1016/J.Jalz.2006.05.1817  0.445
2005 Cantuti-Castelvetri I, Klucken J, Ingelsson M, Ramasamy K, McLean PJ, Frosch MP, Hyman BT, Standaert DG. Alpha-synuclein and chaperones in dementia with Lewy bodies. Journal of Neuropathology and Experimental Neurology. 64: 1058-66. PMID 16319716 DOI: 10.1097/01.Jnen.0000190063.90440.69  0.436
2005 Domnitz SB, Robbins EM, Hoang AW, Garcia-Alloza M, Hyman BT, Rebeck GW, Greenberg SM, Bacskai BJ, Frosch MP. Progression of cerebral amyloid angiopathy in transgenic mouse models of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 64: 588-94. PMID 16042310 DOI: 10.1097/01.Jnen.0000171644.00180.Fc  0.553
2005 Berezovska O, Lleo A, Herl LD, Frosch MP, Stern EA, Bacskai BJ, Hyman BT. Familial Alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3009-17. PMID 15772361 DOI: 10.1523/Jneurosci.0364-05.2005  0.489
2004 Hutter-Paier B, Huttunen HJ, Puglielli L, Eckman CB, Kim DY, Hofmeister A, Moir RD, Domnitz SB, Frosch MP, Windisch M, Kovacs DM. The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease. Neuron. 44: 227-38. PMID 15473963 DOI: 10.1016/J.Neuron.2004.08.043  0.409
2004 Lleó A, Berezovska O, Herl L, Raju S, Deng A, Bacskai BJ, Frosch MP, Irizarry M, Hyman BT. Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation. Nature Medicine. 10: 1065-6. PMID 15448688 DOI: 10.1038/Nm1112  0.442
2004 Ingelsson M, Fukumoto H, Newell KL, Growdon JH, Hedley-Whyte ET, Frosch MP, Albert MS, Hyman BT, Irizarry MC. Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain. Neurology. 62: 925-31. PMID 15037694 DOI: 10.1212/01.Wnl.0000115115.98960.37  0.68
2004 Eng JA, Frosch MP, Choi K, Rebeck GW, Greenberg SM. Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Annals of Neurology. 55: 250-6. PMID 14755729 DOI: 10.1002/Ana.10810  0.331
2004 Ingelsson M, Cantuti-Castelvetri I, Ramasamy K, Orne JD, Augustinack JC, Vanderburg CR, Growdon JH, Frosch MP, Irizarry MC, Standaert DG, Hyman BT. P3-229 Analysis of gene expression in the Alzheimer's disease brain Neurobiology of Aging. 25: S420. DOI: 10.1016/S0197-4580(04)81379-4  0.496
2003 Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP, Selkoe DJ. Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron. 40: 1087-93. PMID 14687544 DOI: 10.1016/S0896-6273(03)00787-6  0.394
2003 Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, Eckman CB, Tanzi RE, Selkoe DJ, Guenette S. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 4162-7. PMID 12634421 DOI: 10.1073/Pnas.0230450100  0.353
2003 Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ. The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease. Neuron. 37: 583-95. PMID 12597857 DOI: 10.1016/S0896-6273(03)00024-2  0.306
2002 Achim C, Auer R, Bergeron C, Cardozo A, Deprez M, de Vos R, Duyckaerts C, Egensperger R, Esiri M, Frosch MP, Giannini C, Goebel HH, Graeber MB, Graham DI, Gray F, et al. Global democratic consensus on neuropathological disease criteria. The Lancet. Neurology. 1: 340. PMID 12849392 DOI: 10.1016/S1474-4422(02)00156-4  0.304
2002 Klunk WE, Bacskai BJ, Mathis CA, Kajdasz ST, McLellan ME, Frosch MP, Debnath ML, Holt DP, Wang Y, Hyman BT. Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. Journal of Neuropathology and Experimental Neurology. 61: 797-805. PMID 12230326 DOI: 10.1093/Jnen/61.9.797  0.434
2002 Schlossmacher MG, Frosch MP, Gai WP, Medina M, Sharma N, Forno L, Ochiishi T, Shimura H, Sharon R, Hattori N, Langston JW, Mizuno Y, Hyman BT, Selkoe DJ, Kosik KS. Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. The American Journal of Pathology. 160: 1655-67. PMID 12000718 DOI: 10.1016/S0002-9440(10)61113-3  0.438
2002 Mathis CA, Bacskai BJ, Kajdasz ST, McLellan ME, Frosch MP, Hyman BT, Holt DP, Wang Y, Huang GF, Debnath ML, Klunk WE. A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain. Bioorganic & Medicinal Chemistry Letters. 12: 295-8. PMID 11814781 DOI: 10.1016/S0960-894X(01)00734-X  0.496
2001 Scinto LF, Frosch M, Wu CK, Daffner KR, Gedi N, Geula C. Selective cell loss in Edinger-Westphal in asymptomatic elders and Alzheimer's patients. Neurobiology of Aging. 22: 729-36. PMID 11705632 DOI: 10.1016/S0197-4580(01)00235-4  0.397
2000 Yoo AS, Cheng I, Chung S, Grenfell TZ, Lee H, Pack-Chung E, Handler M, Shen J, Xia W, Tesco G, Saunders AJ, Ding K, Frosch MP, Tanzi RE, Kim TW. Presenilin-mediated modulation of capacitative calcium entry. Neuron. 27: 561-72. PMID 11055438 DOI: 10.1016/S0896-6273(00)00066-0  0.328
2000 Chan AW, Tarbell NJ, Black PM, Louis DN, Frosch MP, Ancukiewicz M, Chapman P, Loeffler JS. Adult medulloblastoma: prognostic factors and patterns of relapse. Neurosurgery. 47: 623-31; discussion 6. PMID 10981749 DOI: 10.1097/00006123-200009000-00018  0.469
2000 Sawamura N, Morishima-Kawashima M, Waki H, Kobayashi K, Kuramochi T, Frosch MP, Ding K, Ito M, Kim TW, Tanzi RE, Oyama F, Tabira T, Ando S, Ihara Y. Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin. The Journal of Biological Chemistry. 275: 27901-8. PMID 10846187 DOI: 10.1074/Jbc.M004308200  0.326
1999 Berezovska O, Frosch M, McLean P, Knowles R, Koo E, Kang D, Shen J, Lu FM, Lux SE, Tonegawa S, Hyman BT. The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons. Brain Research. Molecular Brain Research. 69: 273-80. PMID 10366748 DOI: 10.1016/S0169-328X(99)00119-9  0.465
1998 Simon DK, Rodriguez ML, Frosch MP, Quackenbush EJ, Feske SK, Natowicz MR. A unique familial leukodystrophy with adult onset dementia and abnormal glycolipid storage: a new lysosomal disease? Journal of Neurology, Neurosurgery, and Psychiatry. 65: 251-4. PMID 9703182 DOI: 10.1136/Jnnp.65.2.251  0.335
1997 Stemmer-Rachamimov AO, Horgan MA, Taratuto AL, Munoz DG, Smith TW, Frosch MP, Louis DN. Meningioangiomatosis is associated with neurofibromatosis 2 but not with somatic alterations of the NF2 gene. Journal of Neuropathology and Experimental Neurology. 56: 485-9. PMID 9143261 DOI: 10.1097/00005072-199705000-00004  0.464
1997 Frosch MP, Collins T, Zhang J, Ahn P, Berezovskaja O, Xia M, Hyman BT, Koo EH. TRANSGENIC MICE EXPRESSING MUTANT AND WILD TYPE HUMAN PRESENILIN-I (PS-1) Journal of Neuropathology and Experimental Neurology. 56: 571. DOI: 10.1097/00005072-199705000-00014  0.395
Low-probability matches (unlikely to be authored by this person)
2018 Mengel D, Hong W, Corbett GT, Liu W, DeSousa A, Solforosi L, Fang C, Frosch MP, Collinge J, Harris D, Walsh DM. PrP-grafted antibodies bind certain amyloid β-protein aggregates, but do not prevent toxicity. Brain Research. PMID 30593771 DOI: 10.1016/J.Brainres.2018.12.038  0.3
2008 Nakagawa K, Sheikh SI, Snuderl M, Frosch MP, Greenberg SM. A new Thr49Pro transthyretin gene mutation associated with leptomeningeal amyloidosis. Journal of the Neurological Sciences. 272: 186-90. PMID 18579156 DOI: 10.1016/J.Jns.2008.05.014  0.298
2019 Brickhouse M, Flaherty R, Getchell K, Krahn E, Delp T, O'Chander R, Krivensky S, Zaitsev A, Brandt K, Kim S, Cordella C, Dev S, Touroutoglou A, Putcha D, Wong B, ... ... Frosch MP, et al. P3-413: Mri-Derived Cortical Atrophy Patterns As Probabilistic Predictors Of Specific Neurodegenerative Pathologies Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3447  0.296
2018 Magnain C, Augustinack JC, Tirrell L, Fogarty M, Frosch MP, Boas D, Fischl B, Rockland KS. Colocalization of neurons in optical coherence microscopy and Nissl-stained histology in Brodmann's area 32 and area 21. Brain Structure & Function. PMID 30328512 DOI: 10.1007/S00429-018-1777-Z  0.296
2004 Robbins EM, Domnitz SB, Rebeck G, Greenberg SM, Frosch MP, Bacskai BJ. P2-076 Progression of cerebrovascular β-amyloid deposition in living mice Neurobiology of Aging. 25: S245. DOI: 10.1016/S0197-4580(04)80823-6  0.295
2023 Wang Z, Jin M, Hong W, Liu W, Reczek D, Lagomarsino VN, Hu Y, Weeden T, Frosch MP, Young-Pearse TL, Pradier L, Selkoe D, Walsh DM. Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics. Acta Neuropathologica Communications. 11: 39. PMID 36899414 DOI: 10.1186/s40478-023-01511-2  0.294
2020 Shih DJH, Nayyar N, Bihun I, Dagogo-Jack I, Gill CM, Aquilanti E, Bertalan M, Kaplan A, D'Andrea MR, Chukwueke U, Ippen FM, Alvarez-Breckenridge C, Camarda ND, Lastrapes M, McCabe D, ... ... Frosch MP, et al. Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma. Nature Genetics. PMID 32203465 DOI: 10.1038/S41588-020-0592-7  0.294
2014 Nuytemans K, Inchausti V, Beecham GW, Wang L, Dickson DW, Trojanowski JQ, Lee VM, Mash DC, Frosch MP, Foroud TM, Honig LS, Montine TJ, Dawson TM, Martin ER, Scott WK, et al. Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 827-30. PMID 24573903 DOI: 10.1002/Mds.25838  0.294
2023 Taddei RN, Perbet R, Mate de Gerando A, Wiedmer AE, Sanchez-Mico M, Connors Stewart T, Gaona A, Melloni A, Amaral AC, Duff K, Frosch MP, Gómez-Isla T. Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease. Jama Neurology. 80: 1209-1221. PMID 37812432 DOI: 10.1001/jamaneurol.2023.3530  0.294
2017 Gong Y, Sasidharan N, Laheji F, Frosch M, Musolino P, Tanzi R, Kim DY, Biffi A, El Khoury J, Eichler F. Microglial dysfunction as a key pathologic change in adrenomyeloneuropathy. Annals of Neurology. PMID 29059709 DOI: 10.1002/Ana.25085  0.293
2015 Martinez-Ramirez S, Romero JR, Shoamanesh A, McKee AC, Van Etten E, Pontes-Neto O, Macklin EA, Ayres A, Auriel E, Himali JJ, Beiser AS, DeCarli C, Stein TD, Alvarez VE, Frosch MP, et al. Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26079413 DOI: 10.1016/J.Jalz.2015.04.009  0.292
2016 Hopfner F, Haubenberger D, Galpern WR, Gwinn K, Van't Veer A, White S, Bhatia K, Adler CH, Eidelberg D, Ondo W, Stebbins GT, Tanner CM, Helmich RC, Lenz FA, Sillitoe RV, ... ... Frosch MP, et al. Knowledge gaps and research recommendations for essential tremor. Parkinsonism & Related Disorders. PMID 27769649 DOI: 10.1016/J.Parkreldis.2016.10.002  0.291
2017 Frosch MP. Tau aggregates: Where, When, Why and What consequences? Neuropathology and Applied Neurobiology. PMID 28370167 DOI: 10.1111/nan.12401  0.291
2005 Augustinack JC, van der Kouwe AJ, Blackwell ML, Salat DH, Wiggins CJ, Frosch MP, Wiggins GC, Potthast A, Wald LL, Fischl BR. Detection of entorhinal layer II using 7Tesla [corrected] magnetic resonance imaging. Annals of Neurology. 57: 489-94. PMID 15786476 DOI: 10.1002/Ana.20426  0.291
2001 Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, Mizuno Y, Kosik KS, Selkoe DJ. Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science (New York, N.Y.). 293: 263-9. PMID 11431533 DOI: 10.1126/Science.1060627  0.29
2016 van Veluw SJ, Charidimou A, van der Kouwe AJ, Lauer A, Reijmer YD, Costantino I, Gurol ME, Biessels GJ, Frosch MP, Viswanathan A, Greenberg SM. Microbleed and microinfarct detection in amyloid angiopathy: a high-resolution MRI-histopathology study. Brain : a Journal of Neurology. PMID 27645801 DOI: 10.1093/Brain/Aww229  0.289
2018 Lee CM, Jacobs HIL, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KA. 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus Signal. Journal of Alzheimer's Disease : Jad. 62: 1691-1702. PMID 29614677 DOI: 10.3233/Jad-170840  0.289
2018 Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, et al. Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease. Nature Neuroscience. PMID 30224808 DOI: 10.1038/S41593-018-0223-0  0.288
2017 Ysselstein D, Dehay B, Costantino IM, McCabe GP, Frosch MP, George JM, Bezard E, Rochet JC. Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity. Acta Neuropathologica Communications. 5: 3. PMID 28069058 DOI: 10.1186/S40478-016-0403-7  0.287
2015 Beecham GW, Dickson DW, Scott WK, Martin ER, Schellenberg G, Nuytemans K, Larson EB, Buxbaum JD, Trojanowski JQ, Van Deerlin VM, Hurtig HI, Mash DC, Beach TG, Troncoso JC, Pletnikova O, ... Frosch MP, et al. PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease. Neurology. 84: 972-80. PMID 25663231 DOI: 10.1212/Wnl.0000000000001332  0.287
2009 Chu-Shore CJ, Frosch MP, Grant PE, Thiele EA. Progressive multifocal cystlike cortical tubers in tuberous sclerosis complex: Clinical and neuropathologic findings. Epilepsia. 50: 2648-51. PMID 19624715 DOI: 10.1111/J.1528-1167.2009.02193.X  0.286
2022 Gómez-Isla T, Frosch MP. Lesions without symptoms: understanding resilience to Alzheimer disease neuropathological changes. Nature Reviews. Neurology. PMID 35332316 DOI: 10.1038/s41582-022-00642-9  0.286
2013 Snuderl M, Wirth D, Sheth SA, Bourne SK, Kwon CS, Ancukiewicz M, Curry WT, Frosch MP, Yaroslavsky AN. Dye-enhanced multimodal confocal imaging as a novel approach to intraoperative diagnosis of brain tumors. Brain Pathology (Zurich, Switzerland). 23: 73-81. PMID 22882328 DOI: 10.1111/J.1750-3639.2012.00626.X  0.286
2013 Valencia A, Sapp E, Kimm JS, McClory H, Reeves PB, Alexander J, Ansong KA, Masso N, Frosch MP, Kegel KB, Li X, DiFiglia M. Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease. Human Molecular Genetics. 22: 1112-31. PMID 23223017 DOI: 10.1093/Hmg/Dds516  0.286
2020 Ter Telgte A, Scherlek AA, Reijmer YD, van der Kouwe AJ, van Harten T, Duering M, Bacskai BJ, de Leeuw FE, Frosch MP, Greenberg SM, van Veluw SJ. Histopathology of diffusion-weighted imaging-positive lesions in cerebral amyloid angiopathy. Acta Neuropathologica. PMID 32108259 DOI: 10.1007/S00401-020-02140-Y  0.284
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Frosch MP, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536  0.283
1991 Sasahara M, Fries JW, Raines EW, Gown AM, Westrum LE, Frosch MP, Bonthron DT, Ross R, Collins T. PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model. Cell. 64: 217-27. PMID 1986868 DOI: 10.1016/0092-8674(91)90223-L  0.283
2010 Hutter-Paier B, Huttunen HJ, Puglielli L, Eckman CB, Kim DY, Hofmeister A, Moir RD, Domnitz SB, Frosch MP, Windisch M, Kovacs DM. The ACAT Inhibitor CP-113,818 Markedly Reduces Amyloid Pathology in a Mouse Model of Alzheimer's Disease Neuron. 68: 1014. DOI: 10.1016/j.neuron.2010.11.028  0.283
2021 Perosa V, Oltmer J, Munting LP, Freeze WM, Auger CA, Scherlek AA, van der Kouwe AJ, Iglesias JE, Atzeni A, Bacskai BJ, Viswanathan A, Frosch MP, Greenberg SM, van Veluw SJ. Perivascular space dilation is associated with vascular amyloid-β accumulation in the overlying cortex. Acta Neuropathologica. PMID 34928427 DOI: 10.1007/s00401-021-02393-1  0.282
2015 Iglesias JE, Augustinack JC, Nguyen K, Player CM, Player A, Wright M, Roy N, Frosch MP, McKee AC, Wald LL, Fischl B, Van Leemput K. A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI. Neuroimage. 115: 117-37. PMID 25936807 DOI: 10.1016/J.Neuroimage.2015.04.042  0.281
2023 Llamas-Rodríguez J, Oltmer J, Marshall M, Champion S, Frosch MP, Augustinack JC. TDP-43 and tau concurrence in the entorhinal subfields in primary age-related tauopathy and preclinical Alzheimer's disease. Brain Pathology (Zurich, Switzerland). e13159. PMID 37037195 DOI: 10.1111/bpa.13159  0.281
2003 Wulffraat NM, Haas PJ, Frosch M, Kleer IMd, Vogl T, Brinkman DMC, Quartier P, Roth J, Kuis W. Myeloid related protein 8 and 14 secretion reflects phagocyte activation and correlates with disease activity in juvenile idiopathic arthritis treated with autologous stem cell transplantation. Annals of the Rheumatic Diseases. 62: 236-241. PMID 12594109 DOI: 10.1136/Ard.62.3.236  0.278
2015 Magnain C, Augustinack JC, Konukoglu E, Frosch MP, Sakadži? S, Varjabedian A, Garcia N, Wedeen VJ, Boas DA, Fischl B. Optical coherence tomography visualizes neurons in human entorhinal cortex. Neurophotonics. 2: 015004. PMID 25741528 DOI: 10.1117/1.Nph.2.1.015004  0.278
2009 Garcia-Alloza M, Prada C, Lattarulo C, Fine S, Borrelli LA, Betensky R, Greenberg SM, Frosch MP, Bacskai BJ. Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice. Journal of Neurochemistry. 109: 1636-47. PMID 19457117 DOI: 10.1111/J.1471-4159.2009.06096.X  0.278
2016 Singhal AB, Topcuoglu MA, Fok JW, Kursun O, Nogueira RG, Frosch MP, Caviness VS. RCVS and PACNS: Clinical, imaging, and angiographic comparison. Annals of Neurology. PMID 27043703 DOI: 10.1002/Ana.24652  0.277
2011 Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, Brooks WS, Halliday GM, Kril JJ, ... ... Frosch MP, et al. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Archives of Neurology. 68: 488-97. PMID 21482928 DOI: 10.1001/Archneurol.2011.53  0.276
2012 Greenberg CH, Frosch MP, Goldstein JN, Rosand J, Greenberg SM. Modeling intracerebral hemorrhage growth and response to anticoagulation. Plos One. 7: e48458. PMID 23119028 DOI: 10.1371/Journal.Pone.0048458  0.275
2008 Garcia-Alloza M, Prada C, Robbins EM, Betensky RA, Greenberg SM, Frosch MP, Bacskai BJ. P1-460: Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1043  0.275
2021 Hubbard EE, Heil LR, Merrihew GE, Chhatwal JP, Farlow MR, McLean CA, Ghetti B, Newell KL, Frosch MP, Bateman RJ, Larson EB, Keene CD, Perrin RJ, Montine TJ, MacCoss MJ, et al. Does Data-Independent Acquisition Data Contain Hidden Gems? A Case Study Related to Alzheimer's Disease. Journal of Proteome Research. PMID 34818016 DOI: 10.1021/acs.jproteome.1c00558  0.274
2017 Saygin ZM, Kliemann D, Iglesias JE, van der Kouwe AJW, Boyd E, Reuter M, Stevens A, Van Leemput K, McKee A, Frosch MP, Fischl B, Augustinack JC. High-resolution magnetic resonance imaging reveals nuclei of the human amygdala: manual segmentation to automatic atlas. Neuroimage. PMID 28479476 DOI: 10.1016/J.Neuroimage.2017.04.046  0.273
2010 Gerstner ER, Frosch MP, Batchelor TT. Reply to J. Rieger et al Journal of Clinical Oncology. 28: e478-e478. DOI: 10.1200/Jco.2010.29.2474  0.273
2012 Wirth D, Snuderl M, Sheth S, Kwon CS, Frosch MP, Curry W, Yaroslavsky AN. Identifying brain neoplasms using dye-enhanced multimodal confocal imaging. Journal of Biomedical Optics. 17: 026012. PMID 22463044 DOI: 10.1117/1.Jbo.17.2.026012  0.273
2012 Augustinack JC, Huber KE, Postelnicu GM, Frosch MP, Pienaar R, Fischl B. Entorhinal verrucae correlate with surface geometry Translational Neuroscience. 3: 123-131. DOI: 10.2478/S13380-012-0019-8  0.269
2005 McCampbell A, Truong D, Broom DC, Allchorne A, Gable K, Cutler RG, Mattson MP, Woolf CJ, Frosch MP, Harmon JM, Dunn TM, Brown RH. Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy. Human Molecular Genetics. 14: 3507-21. PMID 16210380 DOI: 10.1093/Hmg/Ddi380  0.269
2014 Augustinack JC, van der Kouwe AJ, Salat DH, Benner T, Stevens AA, Annese J, Fischl B, Frosch MP, Corkin S. H.M.'s contributions to neuroscience: a review and autopsy studies. Hippocampus. 24: 1267-86. PMID 25154857 DOI: 10.1002/Hipo.22354  0.268
2018 Park YG, Sohn CH, Chen R, McCue M, Yun DH, Drummond GT, Ku T, Evans NB, Oak HC, Trieu W, Choi H, Jin X, Lilascharoen V, Wang J, Truttmann MC, ... ... Frosch MP, et al. Protection of tissue physicochemical properties using polyfunctional crosslinkers. Nature Biotechnology. PMID 30556815 DOI: 10.1038/Nbt.4281  0.267
2008 Eichler FS, Ren JQ, Cossoy M, Rietsch AM, Nagpal S, Moser AB, Frosch MP, Ransohoff RM. Is microglial apoptosis an early pathogenic change in cerebral X-linked adrenoleukodystrophy? Annals of Neurology. 63: 729-42. PMID 18571777 DOI: 10.1002/Ana.21391  0.266
2019 Nayyar N, White MD, Gill CM, Lastrapes M, Bertalan M, Kaplan A, D'Andrea MR, Bihun I, Kaneb A, Dietrich J, Ferry JA, Martinez-Lage M, Giobbie-Hurder A, Borger DR, Rodriguez FJ, ... Frosch MP, et al. L265P mutation and loss are early mutational events in primary central nervous system diffuse large B-cell lymphomas. Blood Advances. 3: 375-383. PMID 30723112 DOI: 10.1182/Bloodadvances.2018027672  0.265
2009 Eichler FS, Hornemann T, McCampbell A, Kuljis D, Penno A, Vardeh D, Tamrazian E, Garofalo K, Lee HJ, Kini L, Selig M, Frosch M, Gable K, von Eckardstein A, Woolf CJ, et al. Overexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14646-51. PMID 19923297 DOI: 10.1523/Jneurosci.2536-09.2009  0.264
2011 Dressler F, Frosch M, Mönkemöller K, Thon A, Weißbarth-Riedel E, Horneff G. Results of the German ESPED-Recording of New Patients with Juvenile Dermatomyositis (JDM) Klinische Padiatrie. 223: 280-282. PMID 21509712 DOI: 10.1055/S-0031-1273723  0.261
2019 Williams SR, Juratli TA, Castro BA, Lazaro TT, Gill CM, Nayyar N, Strickland MR, Babinski M, Johnstone SE, Frosch MP, Silverman IM, Ely HA, Kaplan AB, D'Andrea MR, Bihun IV, et al. Genomic Analysis of Posterior Fossa Meningioma Demonstrates Frequent Mutations in Foramen Magnum Meningiomas. Journal of Neurological Surgery. Part B, Skull Base. 80: 562-567. PMID 31750041 DOI: 10.1055/S-0038-1676821  0.261
2022 Charidimou A, Boulouis G, Frosch MP, Baron JC, Pasi M, Albucher JF, Banerjee G, Barbato C, Bonneville F, Brandner S, Calviere L, Caparros F, Casolla B, Cordonnier C, Delisle MB, et al. The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study. The Lancet. Neurology. 21: 714-725. PMID 35841910 DOI: 10.1016/S1474-4422(22)00208-3  0.26
2010 Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nature Neuroscience. 13: 1396-403. PMID 20953194 DOI: 10.1038/Nn.2660  0.26
2010 Gerstner ER, Frosch MP, Batchelor TT. Diffusion magnetic resonance imaging detects pathologically confirmed, nonenhancing tumor progression in a patient with recurrent glioblastoma receiving bevacizumab. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: e91-3. PMID 19933906 DOI: 10.1200/Jco.2009.25.0233  0.259
1993 Logigian EL, Shefner JM, Frosch MP, Kloman AS, Raynor EM, Adelman LS, Hollander D. Nonvasculitic, steroid-responsive mononeuritis multiplex. Neurology. 43: 879-83. PMID 8492941 DOI: 10.1212/Wnl.43.5.879  0.259
2017 Mesulam MM, Dickerson BC, Sherman JC, Hochberg D, Gonzalez RG, Johnson KA, Frosch MP. Case 1-2017. The New England Journal of Medicine. 376: 158-167. PMID 28076711 DOI: 10.1056/Nejmcpc1613459  0.257
2017 Wang H, Magnain C, Wang R, Dubb J, Varjabedian A, Tirrell LS, Stevens A, Augustinack JC, Konukoglu E, Aganj I, Frosch MP, Schmahmann JD, Fischl B, Boas DA. as-PSOCT: Volumetric microscopic imaging of human brain architecture and connectivity. Neuroimage. PMID 29017866 DOI: 10.1016/J.Neuroimage.2017.10.012  0.256
2019 Nayyar N, Shih D, Bihun I, Dagogo-Jack I, Gill C, Aquilanti E, Bertalan M, Kaplan A, D’Andrea M, Chukwueke U, Ippen F, Alvarez-Breckenridge C, Camarda N, Lastrapes M, McCabe D, ... ... Frosch M, et al. Gene-63. Genomic Characterization Of Human Brain Metastases Identifies Novel Drivers Of Lung Adenocarcinoma Progression Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.465  0.256
2015 Walker MA, Sweetser DA, Thibert RL, Frosch MP. A 15year-old girl with progressive epileptic encephalopathy, progressive myoclonus, and compound heterozygous FARS2 mutations Mitochondrion. 24: S13-S14. DOI: 10.1016/J.Mito.2015.07.044  0.256
2010 Cahill DP, Barker FG, Davis KR, Kalva SP, Sahai I, Frosch MP. Case records of the Massachusetts General Hospital. Case 10-2010. A 37-year-old woman with weakness and a mass in the brain. The New England Journal of Medicine. 362: 1326-33. PMID 20375410 DOI: 10.1056/Nejmcpc1000960  0.255
2016 Mitchell SB, Lucente D, Larvie M, Cobos MI, Frosch M, Dickerson BC. A 63-Year-Old Man With Progressive Visual Symptoms. Jama Neurology. PMID 27842190 DOI: 10.1001/Jamaneurol.2016.2210  0.254
2018 Beaulieu-Laroche L, Toloza EHS, van der Goes MS, Lafourcade M, Barnagian D, Williams ZM, Eskandar EN, Frosch MP, Cash SS, Harnett MT. Enhanced Dendritic Compartmentalization in Human Cortical Neurons. Cell. 175: 643-651.e14. PMID 30340039 DOI: 10.1016/J.Cell.2018.08.045  0.253
2022 Taddei RN, Sanchez-Mico MV, Bonnar O, Connors T, Gaona A, Denbow D, Frosch MP, Gómez-Isla T. Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages. Acta Neuropathologica Communications. 10: 72. PMID 35534858 DOI: 10.1186/s40478-022-01370-3  0.253
2016 Yanamadala V, Koffie RM, Shankar GM, Kumar JI, Buchlak QD, Puthenpura V, Frosch MP, Gudewicz TM, Borges LF, Shin JH. Spinal cord glioblastoma: 25years of experience from a single institution. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 26755453 DOI: 10.1016/J.Jocn.2015.11.011  0.253
2016 Vodopivec I, Cho TA, Rizzo JF, Frosch MP, Sims KB. Mitochondrial Encephalopathy and Optic Neuropathy Due to m.10158 MT-ND3 Complex I Mutation Presenting in an Adult Patient: Case Report and Review of the Literature. The Neurologist. 21: 61-65. PMID 27348141 DOI: 10.1097/Nrl.0000000000000084  0.252
2006 Augustinack JC, Kouwe Avd, Postelnicu GM, Wiggins GC, Frosch MP, Fischl BR. P2-333: High resolution structural magnetic resonance images of the entorhinal cortex predict the presence of verrucae in 3D reconstruction volumes in control brains Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1173  0.252
2014 Magnain C, Augustinack JC, Reuter M, Wachinger C, Frosch MP, Ragan T, Akkin T, Wedeen VJ, Boas DA, Fischl B. Blockface histology with optical coherence tomography: a comparison with Nissl staining. Neuroimage. 84: 524-33. PMID 24041872 DOI: 10.1016/J.Neuroimage.2013.08.072  0.252
2016 Strickland MR, Gill CM, Nayyar N, D'Andrea MR, Thiede C, Juratli TA, Schackert G, Borger DR, Santagata S, Frosch MP, Cahill DP, Brastianos PK, Barker FG. Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas. Journal of Neurosurgery. 1-7. PMID 27885953 DOI: 10.3171/2016.8.Jns161076  0.251
2008 Xie Z, Culley DJ, Dong Y, Zhang G, Zhang B, Moir RD, Frosch MP, Crosby G, Tanzi RE. The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo. Annals of Neurology. 64: 618-27. PMID 19006075 DOI: 10.1002/Ana.21548  0.251
2002 Arboleda-Velasquez JF, Lopera F, Lopez E, Frosch MP, Sepulveda-Falla D, Gutierrez JE, Vargas S, Medina M, Martinez De Arrieta C, Lebo RV, Slaugenhaupt SA, Betensky RA, Villegas A, Arcos-Burgos M, Rivera D, et al. C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke. Neurology. 59: 277-9. PMID 12136071 DOI: 10.1212/Wnl.59.2.277  0.25
2015 Murray E, Cho JH, Goodwin D, Ku T, Swaney J, Kim SY, Choi H, Park YG, Park JY, Hubbert A, McCue M, Vassallo S, Bakh N, Frosch MP, Wedeen VJ, et al. Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems. Cell. 163: 1500-14. PMID 26638076 DOI: 10.1016/J.Cell.2015.11.025  0.25
1992 Yamaguchi H, Yamazaki T, Lemere CA, Frosch MP, Selkoe DJ. Beta amyloid is focally deposited within the outer basement membrane in the amyloid angiopathy of Alzheimer's disease. An immunoelectron microscopic study. The American Journal of Pathology. 141: 249-59. PMID 1632466  0.25
2006 Ehlert K, Roth J, Frosch M, Fehse N, Zander N, Vormoor J. Farber’s disease without central nervous system involvement: bone-marrow transplantation provides a promising new approach Annals of the Rheumatic Diseases. 65: 1665-1666. PMID 17105855 DOI: 10.1136/Ard.2005.048322  0.25
2000 Scinto LF, Frosch M, Daffner KR, Geula C, Deaconess BI. Specificity of neuronal loss in the Edinger-Westphal nucleus and its clinical implications Neurobiology of Aging. 21: 164. DOI: 10.1016/S0197-4580(00)82074-6  0.25
2004 Dangond F, Hwang D, Camelo S, Pasinelli P, Frosch MP, Stephanopoulos G, Stephanopoulos G, Brown RH, Gullans SR. Molecular signature of late-stage human ALS revealed by expression profiling of postmortem spinal cord gray matter. Physiological Genomics. 16: 229-39. PMID 14645737 DOI: 10.1152/Physiolgenomics.00087.2001  0.249
2021 Amaral AC, Perez-Nievas BG, Siao Tick Chong M, Gonzalez-Martinez A, Argente-Escrig H, Rubio-Guerra S, Commins C, Muftu S, Eftekharzadeh B, Hudry E, Fan Z, Ramanan P, Takeda S, Frosch MP, Wegmann S, et al. Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation. Iscience. 24: 102058. PMID 33554064 DOI: 10.1016/j.isci.2021.102058  0.249
2009 Greenberg SM, Nandigam RN, Delgado P, Betensky RA, Rosand J, Viswanathan A, Frosch MP, Smith EE. Microbleeds versus macrobleeds: evidence for distinct entities. Stroke; a Journal of Cerebral Circulation. 40: 2382-6. PMID 19443797 DOI: 10.1161/Strokeaha.109.548974  0.248
2010 Greenberg SM, Rapalino O, Frosch MP. Case records of the Massachusetts General Hospital. Case 22-2010. An 87-year-old woman with dementia and a seizure. The New England Journal of Medicine. 363: 373-81. PMID 20660406 DOI: 10.1056/Nejmcpc1004364  0.248
2006 Tappe D, Claus H, Kern J, Marzinzig A, Frosch M, Abele-Horn M. First case of febrile bacteremia due to a wild type and small-colony variant of Escherichia coli. European Journal of Clinical Microbiology & Infectious Diseases. 25: 31-34. PMID 16418831 DOI: 10.1007/S10096-005-0072-0  0.248
2019 Pasi M, Rocha E, Samore W, Frosch MP, Viswanathan A, Singhal AB. Premature vascular disease in young adult stroke: a pathology-based case series. Journal of Neurology. PMID 31853711 DOI: 10.1007/S00415-019-09623-3  0.246
1997 Heyderman RS, Klein NJ, Daramola OA, Hammerschmidt S, Frosch M, Robertson BD, Levin M, Ison CA. Induction of human endothelial tissue factor expression by Neisseria meningitidis: the influence of bacterial killing and adherence to the endothelium. Microbial Pathogenesis. 22: 265-74. PMID 9160296 DOI: 10.1006/Mpat.1996.0112  0.246
2015 Auriel E, Westover MB, Bianchi MT, Reijmer Y, Martinez-Ramirez S, Ni J, Van Etten E, Frosch MP, Fotiadis P, Schwab K, Vashkevich A, Boulouis G, Younger AP, Johnson KA, Sperling RA, et al. Estimating Total Cerebral Microinfarct Burden From Diffusion-Weighted Imaging. Stroke; a Journal of Cerebral Circulation. PMID 26159796 DOI: 10.1161/Strokeaha.115.009208  0.245
2022 Josephy-Hernandez S, Brickhouse M, Champion S, Kim DD, Touroutoglou A, Frosch M, Dickerson BC. Clinical, radiologic, and pathologic features of the globular glial tauopathy subtype of frontotemporal lobar degeneration in right temporal variant frontotemporal dementia with salient features of Geschwind syndrome. Neurocase. 1-7. PMID 36251576 DOI: 10.1080/13554794.2022.2130805  0.245
2005 Casey PJ, Black JH, Szabo C, Frosch M, Albadawi H, Chen M, Cambria RP, Watkins MT. Poly(adenosine diphosphate ribose) polymerase inhibition modulates spinal cord dysfunction after thoracoabdominal aortic ischemia-reperfusion. Journal of Vascular Surgery. 41: 99-107. PMID 15696051 DOI: 10.1016/J.Jvs.2004.10.040  0.244
2009 Major P, Rakowski S, Simon MV, Cheng ML, Eskandar E, Baron J, Leeman BA, Frosch MP, Thiele EA. Are cortical tubers epileptogenic? Evidence from electrocorticography. Epilepsia. 50: 147-54. PMID 19125835 DOI: 10.1111/J.1528-1167.2008.01814.X  0.244
2022 Llamas-Rodríguez J, Oltmer J, Greve DN, Williams E, Slepneva N, Wang R, Champion S, Lang-Orsini M, Fischl B, Frosch MP, van der Kouwe AJW, Augustinack JC. Entorhinal Subfield Vulnerability to Neurofibrillary Tangles in Aging and the Preclinical Stage of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 35491780 DOI: 10.3233/JAD-215567  0.244
2007 Cantuti-Castelvetri I, Keller-McGandy C, Bouzou B, Asteris G, Clark TW, Frosch MP, Standaert DG. Effects of gender on nigral gene expression and parkinson disease. Neurobiology of Disease. 26: 606-14. PMID 17412603 DOI: 10.1016/J.Nbd.2007.02.009  0.243
1999 Kang DE, Soriano S, Frosch MP, Collins T, Naruse S, Sisodia SS, Leibowitz G, Levine F, Koo EH. Presenilin 1 Facilitates the Constitutive Turnover of β-Catenin: Differential Activity of Alzheimer’s Disease–Linked PS1 Mutants in the β-Catenin–Signaling Pathway The Journal of Neuroscience. 19: 4229-4237. DOI: 10.1523/Jneurosci.19-11-04229.1999  0.243
2015 Miller BL, Dickerson BC, Lucente DE, Larvie M, Frosch MP. Case records of the Massachusetts General Hospital. Case 9-2015. A 31-year-old man with personality changes and progressive neurologic decline. The New England Journal of Medicine. 372: 1151-62. PMID 25785973 DOI: 10.1056/Nejmcpc1409839  0.243
2018 Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, et al. Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease. Nature Neuroscience. PMID 30482917 DOI: 10.1038/S41593-018-0277-Z  0.242
1998 Gascon GG, Frosch MP. Case 15-1998 The New England Journal of Medicine. 338: 1448-1456. PMID 9583972 DOI: 10.1056/Nejm199805143382008  0.242
2011 Garofalo K, Penno A, Schmidt BP, Lee HJ, Frosch MP, von Eckardstein A, Brown RH, Hornemann T, Eichler FS. Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1. The Journal of Clinical Investigation. 121: 4735-45. PMID 22045570 DOI: 10.1172/Jci57549  0.242
2017 Williams S, Castro B, Lazaro T, Gill C, Nayyar N, Frosch M, Strickland M, Cahill D, II F, Brastianos P. Clinically-actionable Mutations in Posterior Skull Base Meningiomas Journal of Neurological Surgery Part B: Skull Base. 78: S1-S156. DOI: 10.1055/S-0037-1600551  0.241
2019 Schlunk F, Böhm M, Boulouis G, Qin T, Arbel M, Tamim I, Fischer P, Bacskai BJ, Frosch MP, Endres M, Greenberg SM, Ayata C. Secondary Bleeding During Acute Experimental Intracerebral Hemorrhage. Stroke. 50: 1210-1215. PMID 31009358 DOI: 10.1161/Strokeaha.118.021732  0.241
1999 Soriano SG, Coxon A, Wang YF, Frosch MP, Lipton SA, Hickey PR, Mayadas TN. Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury. Stroke; a Journal of Cerebral Circulation. 30: 134-9. PMID 9880401 DOI: 10.1161/01.Str.30.1.134  0.24
2015 Lâm TT, Claus H, Frosch M, Vogel U. Analysis of non-typeable Haemophilus influenzae in invasive disease reveals lack of the capsule locus. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID 26454058 DOI: 10.1016/J.Cmi.2015.09.027  0.239
2018 Giantini Larsen A, Grannan BL, Lee CK, Koch MJ, Williams EA, Frosch MP, Cahill DP. Malignant Melanoma Metastatic to Oligodendroglioma: Case Report and Literature Review of Tumor-to-Tumor Metastasis to Gliomas. Journal of Neuropathology and Experimental Neurology. PMID 29746652 DOI: 10.1093/Jnen/Nly029  0.239
1984 Frosch MP, Dichter MA. Physiology and pharmacology of olfactory bulb neurons in dissociated cell culture. Brain Research. 290: 321-32. PMID 6692147 DOI: 10.1016/0006-8993(84)90950-8  0.238
2004 Koralnik IJ, Schellingerhout D, Frosch MP. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 14-2004. A 66-year-old man with progressive neurologic deficits. The New England Journal of Medicine. 350: 1882-93. PMID 15115835 DOI: 10.1056/Nejmcpc030038  0.237
2007 Duffy KR, Murphy KM, Frosch MP, Livingstone MS. Cytochrome oxidase and neurofilament reactivity in monocularly deprived human primary visual cortex. Cerebral Cortex (New York, N.Y. : 1991). 17: 1283-91. PMID 16831856 DOI: 10.1093/Cercor/Bhl038  0.236
2015 Butovsky O, Jedrychowski MP, Cialic R, Krasemann S, Murugaiyan G, Fanek Z, Greco DJ, Wu PM, Doykan CE, Kiner O, Lawson RJ, Frosch MP, Pochet N, Fatimy RE, Krichevsky AM, et al. Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice. Annals of Neurology. 77: 75-99. PMID 25381879 DOI: 10.1002/Ana.24304  0.235
1996 Vogel U, Steinmetz I, Frosch M. Avoiding artifacts in the infant rat model for bacterial meningitis: use of Sangur test strips for the rapid quantification of blood contamination in cerebrospinal fluid Medical Microbiology and Immunology. 185: 27-30. PMID 8803950 DOI: 10.1007/S004300050011  0.233
1997 Carroll RS, Zhang J, Chauncey BW, Chantziara K, Frosch MP, Black PM. Apoptosis in astrocytic neoplasms. Acta Neurochirurgica. 139: 845-50. PMID 9351989 DOI: 10.1007/Bf01411402  0.232
2018 Moremi N, Claus H, Rutta L, Frosch M, Vogel U, Mshana SE. High carriage rate of extended-spectrum beta-lactamase-producing Enterobacteriaceae among patients admitted for surgery in Tanzanian hospitals with a low rate of endogenous surgical site infections. Journal of Hospital Infection. 100: 47-53. PMID 29852267 DOI: 10.1016/J.Jhin.2018.05.017  0.232
2015 Butovsky O, Jedrychowski MP, Cialic R, Murugaiyan G, Wu PM, Doykan CE, Fanek Z, Greco DJ, Kiner O, Lawson RJ, Frosch MP, Pochet N, Krichevsky AM, Gygi SP, Berry J, et al. Targeting miR-155 restores dysfunctional microglia and ameliorates disease in the SOD1 model of ALS. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 5. PMID 26531345 DOI: 10.1016/J.Ijdevneu.2015.04.023  0.23
1996 Hammerschmidt S, Hilse R, Putten JPMV, Gerardy-Schahn R, Unkmeir A, Frosch M. Modulation of cell surface sialic acid expression in Neisseria meningitidis via a transposable genetic element. The Embo Journal. 15: 192-198. DOI: 10.1002/J.1460-2075.1996.Tb00347.X  0.23
2016 Friedman GN, Grannan BL, Yanamadala V, Shankar GM, Dewitt JC, Puthenpura V, Koffie RM, Macdonald SM, Ebb DH, Frosch MP, Duhaime AC. Rapid Neurological Recovery Following Partial Surgical Resection of Spinal Glioblastoma Multiforme in a Pediatric Patient Presenting With Complete Paraplegia. Journal of Pediatric Hematology/Oncology. PMID 27403775 DOI: 10.1097/Mph.0000000000000637  0.23
1999 Romig T, Kratzer W, Kimmig P, Frosch M, Gaus W, Flegel WA, Gottstein B, Lucius R, Beckh K, Kern P, Bilger B, Dinkel A, Hay B, Jenne L, Kilwinski J, et al. An epidemiologic survey of human alveolar echinococcosis in southwestern Germany American Journal of Tropical Medicine and Hygiene. 61: 566-573. PMID 10548290 DOI: 10.4269/Ajtmh.1999.61.566  0.23
2009 Brass SD, Smith EE, Arboleda-Velasquez JF, Copen WA, Frosch MP. Case records of the Massachusetts General Hospital. Case 12-2009. A 46-year-old man with migraine, aphasia, and hemiparesis and similarly affected family members. The New England Journal of Medicine. 360: 1656-65. PMID 19369672 DOI: 10.1056/Nejmcpc0810839  0.229
1998 Basgoz N, Frosch M. Case 21-1998 The New England Journal of Medicine. 339: 105-112. PMID 9669896 DOI: 10.1056/Nejm199807093390208  0.229
2018 Jones PS, Carroll KT, Koch M, DiCesare JAT, Reitz K, Frosch M, Barker FG, Cahill DP, Curry WT. Isocitrate Dehydrogenase Mutations in Low-Grade Gliomas Correlate With Prolonged Overall Survival in Older Patients. Neurosurgery. PMID 29846690 DOI: 10.1093/Neuros/Nyy149  0.229
2022 Hopfner F, Tietz AK, Ruf VC, Ross OA, Koga S, Dickson D, Aguzzi A, Attems J, Beach T, Beller A, Cheshire WP, van Deerlin V, Desplats P, Deuschl G, Duyckaerts C, ... ... Frosch MP, et al. Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 35997131 DOI: 10.1002/mds.29164  0.229
2014 Krishnamoorthy KS, Eichler F, Rapalino O, Frosch MP. Case records of the Massachusetts General Hospital. Case 14-2014. An 11-month-old girl with developmental delay. The New England Journal of Medicine. 370: 1830-41. PMID 24806163 DOI: 10.1056/Nejmcpc1305987  0.228
2002 Sudoh S, Frosch MP, Wolf BA. Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells. Biochemistry. 41: 1091-9. PMID 11802707 DOI: 10.1021/Bi011193L  0.228
1999 Albarracin CT, Frosch MP, Chin WW. The gonadotropin-releasing hormone receptor gene promoter directs pituitary-specific oncogene expression in transgenic mice. Endocrinology. 140: 2415-21. PMID 10218996 DOI: 10.1210/Endo.140.5.6682  0.228
2001 Hsiao LL, Dangond F, Yoshida T, Hong R, Jensen RV, Misra J, Dillon W, Lee KF, Clark KE, Haverty P, Weng Z, Mutter GL, Frosch MP, MacDonald ME, Milford EL, et al. A compendium of gene expression in normal human tissues. Physiological Genomics. 7: 97-104. PMID 11773596 DOI: 10.1152/Physiolgenomics.00040.2001  0.228
2004 Schlossmacher MG, Hamann C, Cole AG, Gonzalez RG, Frosch MP. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-2004. A 79-year-old woman with disturbances in gait, cognition, and autonomic function. The New England Journal of Medicine. 351: 912-22. PMID 15329430 DOI: 10.1056/Nejmcpc049018  0.227
2017 Piantadosi A, Kanjilal S, Ganesh V, Khanna A, Hyle EP, Rosand J, Bold T, Metsky HC, Lemieux J, Leone MJ, Freimark L, Matranga CB, Adams G, McGrath G, Zamirpour S, ... ... Frosch MP, et al. Rapid detection of Powassan virus in a patient with encephalitis by metagenomic sequencing. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 29020227 DOI: 10.1093/Cid/Cix792  0.227
2010 Pless ML, Chen YB, Copen WA, Frosch MP. Case records of the Massachusetts General Hospital. Case 9-2010. A 37-year-old woman with paresthesias and ataxia. The New England Journal of Medicine. 362: 1129-38. PMID 20335590 DOI: 10.1056/Nejmcpc0910092  0.225
1992 Frosch MP, Dichter MA. Non-uniform distribution of GABA activated chloride channels in cultured cortical neurons. Neuroscience Letters. 138: 59-62. PMID 1383879 DOI: 10.1016/0304-3940(92)90472-J  0.224
2005 Johnson RT, Gonzalez RG, Frosch MP. Case records of the Massachusetts General Hospital. Case 27-2005. An 80-year-old man with fatigue, unsteady gait, and confusion. The New England Journal of Medicine. 353: 1042-50. PMID 16148290 DOI: 10.1056/Nejmcpc059024  0.223
1988 Madison RD, Macklis JD, Frosch MP. Non-invasive laser microsurgery selectively damages populations of labeled mouse neurons: dependence on incident laser dose and absorption. Brain Research. 445: 101-10. PMID 3365549 DOI: 10.1016/0006-8993(88)91078-5  0.222
1992 Frosch MP, Lipton SA, Dichter MA. Desensitization of GABA-activated currents and channels in cultured cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 3042-53. PMID 1379634 DOI: 10.1523/Jneurosci.12-08-03042.1992  0.221
2016 Ronthal M, Venna N, Hunter GJ, Frosch MP. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 15-2016. A 32-Year-Old Man with Olfactory Hallucinations and Paresthesias. The New England Journal of Medicine. 374: 1966-75. PMID 27192675 DOI: 10.1056/Nejmcpc1516449  0.221
2007 Cole AJ, Henson JW, Roehrl MH, Frosch MP. Case records of the Massachusetts General Hospital. Case 24-2007. A 20-year-old pregnant woman with altered mental status. The New England Journal of Medicine. 357: 589-600. PMID 17687135 DOI: 10.1056/Nejmcpc079018  0.22
2008 Major P, Rakowski S, Simon MV, Cheng ML, Eskandar E, Baron J, Leeman BA, Frosch MP, Thiele EA. 5. Are cortical tubers epileptogenic? Evidence from electrocorticography Clinical Neurophysiology. 119. DOI: 10.1016/J.Clinph.2008.04.285  0.22
2002 Thaler DE, Frosch MP. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 16-2002. A 41-year-old woman with global headache and an intracranial mass. The New England Journal of Medicine. 346: 1651-8. PMID 12023999 DOI: 10.1056/Nejmcpc020016  0.218
2010 Nozari A, Dilekoz E, Sukhotinsky I, Stein T, Eikermann-Haerter K, Liu C, Wang Y, Frosch MP, Waeber C, Ayata C, Moskowitz MA. Microemboli may link spreading depression, migraine aura, and patent foramen ovale. Annals of Neurology. 67: 221-9. PMID 20225282 DOI: 10.1002/Ana.21871  0.216
2006 Caviness VS, Sagar P, Israel EJ, Mackool BT, Grabowski EF, Frosch MP. Case records of the Massachusetts General Hospital. Case 38-2006. A 5-year-old boy with headache and abdominal pain. The New England Journal of Medicine. 355: 2575-84. PMID 17167141 DOI: 10.1056/Nejmcpc069029  0.216
2000 Hilse R, Stoevesandt J, Caugant DA, Claus H, Frosch M, Vogel U. Distribution of the meningococcal insertion sequence IS1301 in clonal lineages of Neisseria meningitidis. Epidemiology and Infection. 124: 337-340. PMID 10813160 DOI: 10.1017/S0950268899003647  0.215
2023 Perosa V, Auger CA, Zanon Zotin MC, Oltmer J, Frosch MP, Viswanathan A, Greenberg SM, van Veluw SJ. The histopathological correlates of lobar microbleeds in false-positive cerebral amyloid angiopathy cases. Annals of Neurology. PMID 37548609 DOI: 10.1002/ana.26761  0.214
2003 Kurzai O, Keith P, Hoog Sd, Abele-Horn M, Frosch M. Postmortem isolation of Pseudotaeniolina globosa from a patient with aortic aneurysm. Mycoses. 46: 141-144. PMID 12870204 DOI: 10.1046/J.1439-0507.2003.00866.X  0.214
1996 Vogel U, Hammerschmidt S, Frosch M. Sialic acids of both the capsule and the sialylated lipooligosaccharide of Neisseria meningitis serogroup B are prerequisites for virulence of meningococci in the infant rat Medical Microbiology and Immunology. 185: 81-87. PMID 8884739 DOI: 10.1007/S004300050018  0.213
2001 Cassens U, Garritsen H, Kelsch R, Werf Nvd, Frosch M, Witteler R, Ebell W, Sibrowski W. Platelet glycoprotein complex Ia/IIa antibodies cause neonatal alloimmune thrombocytopenia but do not inhibit megakaryopoiesis and platelet recovery after allogeneic cord blood stem cell transplantation. Bone Marrow Transplantation. 28: 803-806. PMID 11781636 DOI: 10.1038/Sj.Bmt.1703235  0.212
2019 Leak RK, Frosch MP, Beach TG, Halliday GM. Alpha-synuclein: prion or prion-like? Acta Neuropathologica. PMID 31407028 DOI: 10.1007/S00401-019-02057-1  0.211
2001 Muller FM, Kurzai O, Hacker J, Frosch M, Mühlschlegel FA. Effect of the growth medium on the in vitro antifungal activity of micafungin (FK-463) against clinical isolates of Candida dubliniensis Journal of Antimicrobial Chemotherapy. 48: 713-715. PMID 11679561 DOI: 10.1093/Jac/48.5.713  0.211
2020 Ku T, Guan W, Evans NB, Sohn CH, Albanese A, Kim JG, Frosch MP, Chung K. Elasticizing tissues for reversible shape transformation and accelerated molecular labeling. Nature Methods. PMID 32424271 DOI: 10.1038/S41592-020-0823-Y  0.209
1988 Lipton SA, Frosch MP, Phillips MD, Tauck DL, Aizenman E. Nicotinic antagonists enhance process outgrowth by rat retinal ganglion cells in culture. Science (New York, N.Y.). 239: 1293-6. PMID 3344435 DOI: 10.1126/Science.3344435  0.209
1998 Haarmann C, Karch H, Frosch M, Schmidt H. A 3.3-kb Plasmid of EnterohemorrhagicEscherichia coliO157:H7 Is Closely Related to the Core Region of theSalmonella typhimuriumAntibiotic Resistance Plasmid NTP16 Plasmid. 39: 134-140. PMID 9514711 DOI: 10.1006/Plas.1997.1333  0.209
2021 Goodheart AE, Locascio JJ, Samore WR, Collins JA, Brickhouse M, Schultz A, Touroutoglou A, Johnson KA, Frosch MP, Growdon JH, Dickerson BC, Gomperts SN. 18F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome. Brain : a Journal of Neurology. 144: 266-277. PMID 33578418 DOI: 10.1093/brain/awaa383  0.208
2011 Chow FC, Edlow BL, Frosch MP, Copen WA, Greer DM. Outcome in patients with H1N1 influenza and cerebrovascular injury treated with extracorporeal membrane oxygenation. Neurocritical Care. 15: 156-60. PMID 21465323 DOI: 10.1007/S12028-011-9534-7  0.208
1999 Ram S, Mackinnon FG, Gulati S, McQuillen DP, Vogel U, Frosch M, Elkins C, Guttormsen HK, Wetzler LM, Oppermann M, Pangburn MK, Rice PA. The contrasting mechanisms of serum resistance of Neisseria gonorrhoeae and group B Neisseria meningitidis Molecular Immunology. 36: 915-928. PMID 10698346 DOI: 10.1016/S0161-5890(99)00114-5  0.207
2015 Scripko P, Oaklander AL, Koeppen AH, Frosch MP, Schmahmann JD. A 40-year-old woman with difficulty going down stairs in high-heeled shoes. Annals of Neurology. 77: 1-7. PMID 25380064 DOI: 10.1002/Ana.24301  0.206
1988 Aizenman E, Frosch MP, Lipton SA. Responses mediated by excitatory amino acid receptors in solitary retinal ganglion cells from rat. The Journal of Physiology. 396: 75-91. PMID 2842491 DOI: 10.1113/Jphysiol.1988.Sp016951  0.205
2003 Kurzai O, Vaeth T, Hamelmann W, Muller FM, Klinker H, Langmann P, Frosch M, Mühlschlegel FA. Combined surgical and antifungal treatment of a subcutaneous infection due to Paecilomyces lilacinus. Medical Mycology. 41: 253-258. PMID 12964718 DOI: 10.1080/1369378031000147467  0.204
1988 Tauck DL, Frosch MP, Lipton SA. Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture. Neuroscience. 27: 193-203. PMID 3200439 DOI: 10.1016/0306-4522(88)90230-8  0.204
2006 Valenza G, Kallmann B, Berend A, Mlynski R, Nöckler K, Kurzai O, Frosch M, Abele-Horn M. Isolation of Brucella melitensis from a patient with hearing loss. European Journal of Clinical Microbiology & Infectious Diseases. 25: 67-68. PMID 16418830 DOI: 10.1007/S10096-006-0084-4  0.204
1985 Verkman AS, Frosch MP. Temperature-jump studies of merocyanine 540 relaxation kinetics in lipid bilayer membranes. Biochemistry. 24: 7117-22. PMID 4084566 DOI: 10.1021/Bi00346A015  0.199
1999 Schmidt H, Scheef J, Huppertz HI, Frosch M, Karch H. Escherichia coli O157:H7 and O157:H(-) strains that do not produce Shiga toxin: phenotypic and genetic characterization of isolates associated with diarrhea and hemolytic-uremic syndrome. Journal of Clinical Microbiology. 37: 3491-3496. PMID 10523540 DOI: 10.1128/Jcm.37.11.3491-3496.1999  0.198
2016 Jordan J, Batten J, Lennerz J, Frosch M, Iafrate AJ, Batchelor T. MPTH-61. A NOVEL TECHNIQUE TO EXPEDITE MOLECULAR GLIOMA TESTING Neuro-Oncology. 18: vi119-vi119. DOI: 10.1093/Neuonc/Now212.495  0.198
1998 Schmidt H, Maldeghem Jv, Frosch M, Karch H. Antibiotic susceptibilities of verocytotoxin-producing Escherichia coli O157 and non-O157 strains isolated from patients and healthy subjects in Germany during 1996. Journal of Antimicrobial Chemotherapy. 42: 548-550. PMID 9818760 DOI: 10.1093/Jac/42.4.548  0.197
2010 Edlow BL, Wainger BJ, Frosch MP, Copen WA, Rathmell JP, Rost NS. Posterior circulation stroke after C1-C2 intraarticular facet steroid injection: evidence for diffuse microvascular injury. Anesthesiology. 112: 1532-5. PMID 20460995 DOI: 10.1097/Aln.0B013E3181D7B15A  0.197
2006 Costello DJ, Simon MV, Eskandar EN, Frosch MP, Henninger HL, Chiappa KH, Cole AJ. Efficacy of surgical treatment of de novo, adult-onset, cryptogenic, refractory focal status epilepticus. Archives of Neurology. 63: 895-901. PMID 16769873 DOI: 10.1001/Archneur.63.6.895  0.196
2024 Stephen CD, de Gusmao CM, Srinivasan SR, Olsen A, Freua F, Kok F, Montes Garcia Barbosa R, Chen JYH, Appleby BS, Prior T, Frosch MP, Schmahmann JD. Gerstmann-Sträussler-Scheinker Disease Presenting as Late-Onset Slowly Progressive Spinocerebellar Ataxia, and Comparative Case Series with Neuropathology. Movement Disorders Clinical Practice. PMID 38258626 DOI: 10.1002/mdc3.13976  0.194
1998 Feany MB, Zane W, Anthony DC, Frosch MP, Girolami UD. EFFECTS OF METHANOL POISONING ON THE CENTRAL NERVOUS SYSTEM Journal of Neuropathology and Experimental Neurology. 57: 487. DOI: 10.1097/00005072-199805000-00081  0.193
2006 Abele-Horn M, Stoy K, Frosch M, Reinert RR. Comparative evaluation of a new Vitek 2 system for identification and antimicrobial susceptibility testing of Streptococcus pneumoniae. European Journal of Clinical Microbiology & Infectious Diseases. 25: 55-57. PMID 16424974 DOI: 10.1007/S10096-005-0071-1  0.191
2024 Aguero C, Dhaynaut M, Amaral AC, Moon SH, Neelamegam R, Scapellato M, Carazo-Casas C, Kumar S, El Fakhri G, Johnson K, Frosch MP, Normandin MD, Gómez-Isla T. Head-to-head comparison of [F]-Flortaucipir, [F]-MK-6240 and [F]-PI-2620 postmortem binding across the spectrum of neurodegenerative diseases. Acta Neuropathologica. 147: 25. PMID 38280071 DOI: 10.1007/s00401-023-02672-z  0.19
1996 Rodriguez ML, Simon DK, Ouackenbush EJ, Natowicz MR, Frosch MP. ADULT-ONSET LEUKOENCEPHALOPATHY IN TWO SIBLINGS Journal of Neuropathology and Experimental Neurology. 55: 615. DOI: 10.1097/00005072-199605000-00054  0.19
2006 Freeze WM, Greenberg SM, Frosch MP, Jacobs HI, Backes WH, Bacskai B, van Veluw SJ. P2-479: BLOOD-BRAIN BARRIER LEAKAGE AND MICROVASCULAR LESIONS IN CEREBRAL AMYLOID ANGIOPATHY: A POSTMORTEM MRI AND HISTOPATHOLOGY STUDY Alzheimer's & Dementia. 14: P909-P909. DOI: 10.1016/j.jalz.2018.06.1172  0.186
2019 Josephs KA, Mackenzie I, Frosch MP, Bigio EH, Neumann M, Arai T, Dugger BN, Ghetti B, Grossman M, Hasegawa M, Herrup K, Holton J, Jellinger K, Lashley T, McAleese KE, et al. LATE to the PART-y. Brain : a Journal of Neurology. PMID 31359030 DOI: 10.1093/Brain/Awz224  0.181
2023 Nicks R, Clement NF, Alvarez VE, Tripodis Y, Baucom ZH, Huber BR, Mez J, Alosco ML, Aytan N, Cherry JD, Cormier KA, Kubilius C, Mathias R, Svirsky SE, Pothast MJ, ... ... Frosch MP, et al. Repetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis. Acta Neuropathologica. PMID 36681782 DOI: 10.1007/s00401-023-02539-3  0.178
2023 Oltmer J, Greve DN, Cerri S, Slepneva N, Llamas-Rodríguez J, Iglesias JE, Van Leemput K, Champion SN, Frosch MP, Augustinack JC. Assessing individual variability of the entorhinal subfields in health and disease. The Journal of Comparative Neurology. PMID 37700618 DOI: 10.1002/cne.25538  0.177
2022 Jolink WMT, van Veluw SJ, Zwanenburg JJM, Rozemuller AJM, van Hecke W, Frosch MP, Bacskai BJ, Rinkel GJE, Greenberg SM, Klijn CJM. Histopathology of Cerebral Microinfarcts and Microbleeds in Spontaneous Intracerebral Hemorrhage. Translational Stroke Research. PMID 35384634 DOI: 10.1007/s12975-022-01016-5  0.175
2016 Roberts DJ, Frosch MP. Zika and histopathology in first trimester infections. Lancet (London, England). PMID 27372399 DOI: 10.1016/S0140-6736(16)30930-8  0.174
1993 Podlisny MB, Stephenson DT, Frosch MP, Tolan DR, Lieberburg I, Clemens JA, Selkoe DJ. Microinjection of synthetic amyloid beta-protein in monkey cerebral cortex fails to produce acute neurotoxicity. The American Journal of Pathology. 142: 17-24. PMID 8424453  0.173
1997 Vogel U, Lüneberg E, Kuse E-, Neulinger AL, Frosch M. Extragenital Mycoplasma hominis Infection in Two Liver Transplant Recipients Clinical Infectious Diseases. 24: 512-513. PMID 9114209 DOI: 10.1093/Clinids/24.3.512  0.167
2013 McFarland NR, Burdett T, Desjardins CA, Frosch MP, Schwarzschild MA, Nocker M, Scherfler C, Kiechl S, Willeit J, Schmidauer C, Gasperi A, Rungger G, Poewe W, Mahlknecht P, Seppi K, et al. Contents Vol. 12, 2013 Neurodegenerative Diseases. 12. DOI: 10.1159/000355887  0.166
2022 Oltmer J, Slepneva N, Llamas Rodriguez J, Greve DN, Williams EM, Wang R, Champion SN, Lang-Orsini M, Nestor K, Fernandez-Ros N, Fischl B, Frosch MP, Magnain C, van der Kouwe AJW, Augustinack JC. Quantitative and histologically validated measures of the entorhinal subfields in MRI. Brain Communications. 4: fcac074. PMID 35620167 DOI: 10.1093/braincomms/fcac074  0.158
2023 Vardalaki D, Pham TLD, Frosch MP, Cosgrove GR, Richardson M, Cash SS, Harnett MT. Patch2MAP combines patch-clamp electrophysiology with super-resolution structural and protein imaging in identified single neurons without genetic modification. Biorxiv : the Preprint Server For Biology. PMID 36993722 DOI: 10.1101/2023.03.20.533452  0.156
2022 Alvarez-Breckenridge C, Markson SC, Stocking JH, Nayyar N, Lastrapes M, Strickland MR, Kim AE, de Sauvage M, Dahal A, Larson JM, Mora JL, Navia AW, Klein RH, Kuter BM, Gill CM, ... ... Frosch M, et al. Microenvironmental landscape of human melanoma brain metastases in response to immune checkpoint inhibition. Cancer Immunology Research. PMID 35706413 DOI: 10.1158/2326-6066.CIR-21-0870  0.144
2023 Costantini I, Morgan L, Yang J, Balbastre Y, Varadarajan D, Pesce L, Scardigli M, Mazzamuto G, Gavryusev V, Castelli FM, Roffilli M, Silvestri L, Laffey J, Raia S, Varghese M, ... ... Frosch MP, et al. A cellular resolution atlas of Broca's area. Science Advances. 9: eadg3844. PMID 37824623 DOI: 10.1126/sciadv.adg3844  0.141
2023 Oltmer J, Rosenblum EW, Williams EM, Roy J, Llamas-Rodriguez J, Perosa V, Champion SN, Frosch MP, Augustinack JC. Stereology neuron counts correlate with deep learning estimates in the human hippocampal subregions. Scientific Reports. 13: 5884. PMID 37041300 DOI: 10.1038/s41598-023-32903-y  0.139
2022 Cai W, Srivastava P, Feng D, Lin Y, Vanderburg CR, Xu Y, Mclean P, Frosch MP, Fisher DE, Schwarzschild MA, Chen X. Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson's disease. Molecular Neurodegeneration. 17: 16. PMID 35197079 DOI: 10.1186/s13024-022-00520-4  0.139
2000 Du Yan S, Zhu Y, Stern ED, Hwang YC, Hori O, Ogawa S, Frosch MP, Connolly ES, McTaggert R, Pinsky DJ, Clarke S, Stern DM, Ramasamy R. Amyloid beta -peptide-binding alcohol dehydrogenase is a component of the cellular response to nutritional stress. The Journal of Biological Chemistry. 275: 27100-9. PMID 10869339 DOI: 10.1074/jbc.M000055200  0.134
1992 Podlisny MB, Stephenson DT, Frosch MP, Lieberburg I, Clemens JA, Selkoe DJ. Synthetic amyloid beta-protein fails to produce specific neurotoxicity in monkey cerebral cortex. Neurobiology of Aging. 13: 561-7. PMID 1281288 DOI: 10.1016/0197-4580(92)90056-4  0.134
2024 Amaral DG, Augustinack J, Barbas H, Frosch M, Gabrieli J, Luebke J, Rakic P, Rosene D, Rushmore RJ. The analysis of H.M.'s brain: A brief review of status and plans for future studies and tissue archive. Hippocampus. PMID 38189522 DOI: 10.1002/hipo.23597  0.131
2021 Conklin J, Frosch MP, Mukerji SS, Rapalino O, Maher MD, Schaefer PW, Lev MH, Gonzalez RG, Das S, Champion SN, Magdamo C, Sen P, Harrold GK, Alabsi H, Normandin E, et al. Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19. Journal of the Neurological Sciences. 421: 117308. PMID 33497950 DOI: 10.1016/j.jns.2021.117308  0.127
2003 Frosch MP, De Girolami U. Biopsy of the Brain Office Practice of Neurology: Second Edition. 214,CO4-CO5,215-216. DOI: 10.1016/B0-44-306557-8/50025-3  0.121
2023 Gong Y, Laheji F, Berenson A, Li Y, Moser A, Qian A, Frosch M, Sadjadi R, Hahn R, Maguire CA, Eichler F. The Role of Basal Forebrain Neurons in Adrenomyeloneuropathy in Mouse and Human. Annals of Neurology. PMID 38062617 DOI: 10.1002/ana.26849  0.117
2021 Piantadosi A, Mukerji SS, Ye S, Leone MJ, Freimark LM, Park D, Adams G, Lemieux J, Kanjilal S, Solomon IH, Ahmed AA, Goldstein R, Ganesh V, Ostrem B, Cummins KC, ... ... Frosch MP, et al. Enhanced Virus Detection and Metagenomic Sequencing in Patients with Meningitis and Encephalitis. Mbio. 12: e0114321. PMID 34465023 DOI: 10.1128/mBio.01143-21  0.115
2023 Williams EM, Rosenblum EW, Pihlstrom N, Llamas-Rodríguez J, Champion S, Frosch MP, Augustinack JC. Pentad: A reproducible cytoarchitectonic protocol and its application to parcellation of the human hippocampus. Frontiers in Neuroanatomy. 17: 1114757. PMID 36843959 DOI: 10.3389/fnana.2023.1114757  0.113
2021 Beaulieu-Laroche L, Brown NJ, Hansen M, Toloza EHS, Sharma J, Williams ZM, Frosch MP, Cosgrove GR, Cash SS, Harnett MT. Allometric rules for mammalian cortical layer 5 neuron biophysics. Nature. PMID 34759318 DOI: 10.1038/s41586-021-04072-3  0.11
1999 Kang DE, Soriano S, Frosch MP, Collins T, Naruse S, Sisodia SS, Leibowitz G, Levine F, Koo EH. Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4229-37. PMID 10341227  0.107
2023 Halvorsen SC, Benita Y, Hopton M, Hoppe B, Gunnlaugsson HO, Korgaonkar P, Vanderburg CR, Nielsen GP, Trepanowski N, Cheah JH, Frosch MP, Schwab JH, Rosenberg AE, Hornicek FJ, Sassi S. Transcriptional profiling supports the notochordal origin of chordoma and its dependence on a TGFΒ1-TBXT network. The American Journal of Pathology. PMID 36804377 DOI: 10.1016/j.ajpath.2023.01.014  0.106
2021 Liu CJ, Ammon W, Jones RJ, Nolan J, Wang R, Chang S, Frosch MP, Yendiki A, Boas DA, Magnain C, Fischl B, Wang H. Refractive-index matching enhanced polarization sensitive optical coherence tomography quantification in human brain tissue. Biomedical Optics Express. 13: 358-372. PMID 35154876 DOI: 10.1364/BOE.443066  0.103
2020 Conklin J, Frosch MP, Mukerji S, Rapalino O, Maher M, Schaefer PW, Lev MH, Gonzalez RG, Das S, Champion SN, Magdamo C, Sen P, Harrold GK, Alabsi H, Normandin E, et al. Cerebral Microvascular Injury in Severe COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 32743599 DOI: 10.1101/2020.07.21.20159376  0.102
2017 Valencia A, Sapp E, Kimm JS, McClory H, Reeves PB, Alexander J, Ansong KA, Masso N, Frosch MP, Kegel KB, Li X, DiFiglia M. Retracted: Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease. Human Molecular Genetics. PMID 28973680 DOI: 10.1093/hmg/ddx303  0.101
2006 Eichler F, D'Arceuil H, Selig M, Frosch M, Powers J, de Crespigny A. AXONAL ABNORMALITIES IN THE BRAIN OF THE ABCD1 KNOCKOUT MOUSE, AN ANIMAL MODEL OF X-LINKED ADRENOLEUKODYSTROPHY Neuropediatrics. 37. DOI: 10.1055/S-2006-943679  0.101
2022 Kons ZA, Regenhardt RW, Dmytriw AA, Vranic JE, Huynh A, Frosch MP, Borges LF, Patel AB, Romero JM, Stapleton CJ. T2 Hypointense Schwannoma Masquerading As A Vascular Lesion: A Case Report. The Neurohospitalist. 12: 659-663. PMID 36147770 DOI: 10.1177/19418744221112539  0.091
2001 Feany MB, Anthony DC, Frosch MP, Zane W, De Girolami U. August 2000: Two cases with necrosis and hemorrhage in the putamen and white matter. Brain Pathology (Zurich, Switzerland). 11: 121-2, 125. PMID 11145199  0.091
1997 Fischman AJ, Thornton AF, Frosch MP, Swearinger B, Gonzalez RG, Alpert NM. FDG hypermetabolism associated with inflammatory necrotic changes following radiation of meningioma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 38: 1027-9. PMID 9225785  0.089
1995 Zhu J, Frosch MP, Busque L, Beggs AH, Dashner K, Gilliland DG, Black PM. Analysis of meningiomas by methylation- and transcription-based clonality assays. Cancer Research. 55: 3865-72. PMID 7641206  0.081
2014 Venna N, Niles JL, Lev MH, Frosch MP. Case records of the Massachusetts General Hospital. Case 21-2014. A 68-year-old man with a sudden onset of diplopia. The New England Journal of Medicine. 371: 162-73. PMID 25006723 DOI: 10.1056/NEJMcpc1403308  0.077
2022 Leavitt L, Baohan A, Heller H, Kozanno L, Frosch MP, Dunn G. Surgical management of an abscess of the insula. Surgical Neurology International. 13: 591. PMID 36600730 DOI: 10.25259/SNI_871_2022  0.077
2007 Sabatine MS, Poh KK, Mega JL, Shepard JA, Stone JR, Frosch MP. Case records of the Massachusetts General Hospital. Case 36-2007. A 31-year-old woman with rash, fever, and hypotension. The New England Journal of Medicine. 357: 2167-78. PMID 18032767 DOI: 10.1056/NEJMcpc079030  0.069
2015 Butovsky O, Jedrychowski MP, Cialic R, Murugaiyan G, Wu PM, Doykan CE, Fanek Z, Greco DJ, Kiner O, Lawson RJ, Frosch MP, Pochet N, Krichevsky AM, Gygi SP, Berry J, et al. REMOVED: Targeting miR-155 restores dysfunctional microglia and ameliorates disease in the SOD1 model of ALS. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 5. PMID 29887088 DOI: 10.1016/j.ijdevneu.2015.04.023  0.067
2011 Costello DJ, Gonzalez RG, Frosch MP. Case records of the Massachusetts General Hospital. Case 18-2011. A 35-year-old HIV-positive woman with headache and altered mental status. The New England Journal of Medicine. 364: 2343-52. PMID 21675893 DOI: 10.1056/NEJMcpc1007104  0.066
2003 Ronthal M, Gonzalez RG, Smith RN, Frosch MP. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 21-2003. A 72-year-old man with repetitive strokes in the posterior circulation. The New England Journal of Medicine. 349: 170-80. PMID 12853591 DOI: 10.1056/NEJMcpc020034  0.064
2023 Gritsch S, Aghajan Y, Kozanno L, Chiu D, Jordan JT, Frosch MP, Shankar G, Kimberly WT. Teaching NeuroImage: Subacute Quadriparesis From Intramedullary Spinal Cord Infiltrating Glioma With TERT Promoter Mutation. Neurology. PMID 36805433 DOI: 10.1212/WNL.0000000000207148  0.063
2017 Topcuoglu MA, Jha RM, George J, Frosch MP, Singhal AB. Hemorrhagic primary CNS angiitis and vasoconstrictive drug exposure. Neurology. Clinical Practice. 7: 26-34. PMID 28243503 DOI: 10.1212/CPJ.0000000000000324  0.062
2022 Wu Z, Rajan S, Chung HJ, Raffeld M, Panneer Selvam P, Schweizer L, Perry A, Samuel D, Giannini C, Ragunathan A, Frosch MP, Marshall MS, Boué DR, Donev K, Neill SG, et al. Molecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions. Acta Neuropathologica. PMID 36201019 DOI: 10.1007/s00401-022-02508-2  0.056
2022 Dias-Santagata D, Heist RS, Bard AZ, da Silva AFL, Dagogo-Jack I, Nardi V, Ritterhouse LL, Spring LM, Jessop N, Farahani AA, Mino-Kenudson M, Allen J, Goyal L, Parikh A, Misdraji J, ... ... Frosch M, et al. Implementation and Clinical Adoption of Precision Oncology Workflows Across a Healthcare Network. The Oncologist. PMID 35852437 DOI: 10.1093/oncolo/oyac134  0.052
1999 Folkerth RD, Frosch MP, DeGirolami U. “INFLAMMATORY” GLIOMAS Journal of Neuropathology and Experimental Neurology. 58: 510. DOI: 10.1097/00005072-199905000-00016  0.045
1994 Kupsky WJ, Frosch M. Tuberous sclerosis variant with production of Rosenthal fibers (alpha B-crystallin). Pediatric Pathology. 13: 869-73. PMID 8108304 DOI: 10.3109/15513819309048274  0.03
2003 De Girolami U, Frosch MP, Amato AA. Biopsy of Nerve and Muscle Office Practice of Neurology: Second Edition. 217-225. DOI: 10.1016/B0-44-306557-8/50026-5  0.01
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