Hidefumi Ito, MD, PhD - Publications

Affiliations: 
Neurology Kansai Medical University, Hirakata-shi, Ōsaka-fu, Japan 
Website:
http://www.med.kyoto-u.ac.jp/E/grad_school/introduction/1605/

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Takahashi M, Shimokawa T, Koh J, Takeshima T, Yamashita H, Kajimoto Y, Ito H. Effect of istradefylline on postural abnormalities in patients with Parkinson's disease: An association study of baseline postural angle measurements with changes in Unified Dystonia Rating Scale total score. Eneurologicalsci. 34: 100493. PMID 38274039 DOI: 10.1016/j.ensci.2023.100493  0.644
2022 Takahashi M, Shimokawa T, Koh J, Takeshima T, Yamashita H, Kajimoto Y, Mori A, Ito H. Efficacy and safety of istradefylline in patients with Parkinson's disease presenting with postural abnormalities: Results from a multicenter, prospective, and open-label exploratory study in Japan. Journal of the Neurological Sciences. 432: 120078. PMID 34923334 DOI: 10.1016/j.jns.2021.120078  0.652
2020 Hayashida A, Li Y, Yoshino H, Daida K, Ikeda A, Ogaki K, Fuse A, Mori A, Takanashi M, Nakahara T, Yoritaka A, Tomizawa Y, Furukawa Y, Kanai K, Nakayama Y, ... Ito H, et al. The identified clinical features of Parkinson's disease in homo-, heterozygous and digenic variants of PINK1. Neurobiology of Aging. PMID 32713623 DOI: 10.1016/J.Neurobiolaging.2020.06.017  0.527
2020 Kawamoto Y, Ayaki T, Urushitani M, Ito H, Takahashi R. Accumulation of HAX-1 and PARL in brainstem- and cortical-type Lewy bodies in Parkinson's disease and dementia with Lewy bodies. Journal of the Neurological Sciences. 415: 116928. PMID 32470650 DOI: 10.1016/J.Jns.2020.116928  0.343
2019 Suzuki N, Mori-Yoshimura M, Yamashita S, Nakano S, Murata KY, Mori M, Inamori Y, Matsui N, Kimura E, Kusaka H, Kondo T, Ito H, Higuchi I, Hashiguchi A, Nodera H, et al. The updated retrospective questionnaire study of sporadic inclusion body myositis in Japan. Orphanet Journal of Rare Diseases. 14: 155. PMID 31242950 DOI: 10.1186/S13023-019-1122-5  0.534
2019 Yamaguchi Y, Ayaki T, Li F, Tsujimura A, Kamada M, Ito H, Maki T, Sawamoto N, Urushitani M, Takahashi R. Phosphorylated NF-κB subunit p65 aggregates in granulovacuolar degeneration and neurites in neurodegenerative diseases with tauopathy. Neuroscience Letters. PMID 30946927 DOI: 10.1016/J.Neulet.2019.03.036  0.346
2018 Oki R, Izumi Y, Nodera H, Sato Y, Nokihara H, Kanai K, Sonoo M, Urushitani M, Nishinaka K, Atsuta N, Kohara N, Shimizu T, Kikuchi H, Oda M, Ikeda K, ... ... Ito H, et al. The Japanese Early-Stage Trial of High-Dose Methylcobalamin for Amyotrophic Lateral Sclerosis (JETALS): Protocol for a Randomized Controlled Trial. Jmir Research Protocols. 7: e12046. PMID 30578206 DOI: 10.2196/12046  0.359
2017 Ayaki T, Ito H, Komure O, Kamada M, Nakamura M, Wate R, Kusaka H, Yamaguchi Y, Li F, Kawakami H, Urushitani M, Takahashi R. Multiple Proteinopathies in Familial ALS Cases With Optineurin Mutations. Journal of Neuropathology and Experimental Neurology. PMID 29272468 DOI: 10.1093/Jnen/Nlx109  0.598
2017 Honjo Y, Ayaki T, Tomiyama T, Horibe T, Ito H, Mori H, Takahashi R, Kawakami K. Decreased levels of PDI and P5 in oligodendrocytes in Alzheimer's disease. Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 28731225 DOI: 10.1111/Neup.12395  0.311
2017 Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, ... ... Ito H, et al. The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28539470 DOI: 10.1126/Scitranslmed.Aaf3962  0.528
2017 Mitsui J, Koguchi K, Momose T, Takahashi M, Matsukawa T, Yasuda T, Tokushige SI, Ishiura H, Goto J, Nakazaki S, Kondo T, Ito H, Yamamoto Y, Tsuji S. Three-Year Follow-Up of High-Dose Ubiquinol Supplementation in a Case of Familial Multiple System Atrophy with Compound Heterozygous COQ2 Mutations. Cerebellum (London, England). PMID 28150130 DOI: 10.1007/S12311-017-0846-9  0.302
2017 Tsuji K, Nakayama Y, Ayaki T, Hironishi M, Ito H. Comparative immunohistochemical study on the past and the recent kii amyotrophic lateral sclerosis patients Journal of the Neurological Sciences. 381: 717. DOI: 10.1016/J.Jns.2017.08.2019  0.333
2017 Nakanishi I, Yamamoto Y, Ito H. Subjective evaluation of the coaching in patients with Parkinson's disease Journal of the Neurological Sciences. 381: 589. DOI: 10.1016/J.Jns.2017.08.1660  0.483
2016 Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nature Communications. 7: 12547. PMID 27552911 DOI: 10.1038/Ncomms12547  0.339
2016 Murata KY, Nakatani K, Yananeki M, Nakanishi I, Ito H. Anti-U3 ribonucleoprotein antibody-positive inflammatory myopathy: a case report. Journal of Medical Case Reports. 10: 169. PMID 27283724 DOI: 10.1186/S13256-016-0941-4  0.467
2016 Uchida T, Tamaki Y, Ayaki T, Shodai A, Kaji S, Morimura T, Banno Y, Nishitsuji K, Sakashita N, Maki T, Yamashita H, Ito H, Takahashi R, Urushitani M. CUL2-mediated clearance of misfolded TDP-43 is paradoxically affected by VHL in oligodendrocytes in ALS. Scientific Reports. 6: 19118. PMID 26751167 DOI: 10.1038/Srep19118  0.59
2015 Honjo Y, Ayaki T, Tomiyama T, Horibe T, Ito H, Mori H, Takahashi R, Kawakami K. Increased GADD34 in oligodendrocytes in Alzheimer's disease. Neuroscience Letters. 602: 50-5. PMID 26142647 DOI: 10.1016/J.Neulet.2015.06.052  0.326
2015 Murata KY, Maeba A, Yamanegi M, Nakanishi I, Ito H. Methotrexate myelopathy after intrathecal chemotherapy: a case report. Journal of Medical Case Reports. 9: 135. PMID 26055509 DOI: 10.1186/S13256-015-0597-5  0.506
2014 Ayaki T, Ito H, Fukushima H, Inoue T, Kondo T, Ikemoto A, Asano T, Shodai A, Fujita T, Fukui S, Morino H, Nakano S, Kusaka H, Yamashita H, Ihara M, et al. Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant. Acta Neuropathologica Communications. 2: 172. PMID 25492614 DOI: 10.1186/S40478-014-0172-0  0.757
2014 Kawamoto Y, Ito H, Ayaki T, Takahashi R. Immunohistochemical localization of apoptosome-related proteins in Lewy bodies in Parkinson's disease and dementia with Lewy bodies. Brain Research. 1571: 39-48. PMID 24835407 DOI: 10.1016/J.Brainres.2014.05.007  0.311
2014 Ito H. Basophilic inclusions and neuronal intermediate filament inclusions in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 34: 589-95. PMID 24673472 DOI: 10.1111/Neup.12119  0.341
2014 Honjo Y, Horibe T, Torisawa A, Ito H, Nakanishi A, Mori H, Komiya T, Takahashi R, Kawakami K. Protein disulfide isomerase P5-immunopositive inclusions in patients with Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 38: 601-9. PMID 24037032 DOI: 10.3233/Jad-130632  0.303
2014 Oono M, Okado-Matsumoto A, Shodai A, Ido A, Ohta Y, Abe K, Ayaki T, Ito H, Takahashi R, Taniguchi N, Urushitani M. Transglutaminase 2 accelerates neuroinflammation in amyotrophic lateral sclerosis through interaction with misfolded superoxide dismutase 1. Journal of Neurochemistry. 128: 403-18. PMID 24032595 DOI: 10.1111/Jnc.12441  0.376
2014 Kawamoto Y, Ito H, Ihara M, Takahashi R. XIAP immunoreactivity in glial and neuronal cytoplasmic inclusions in multiple system atrophy. Clinical Neuropathology. 33: 76-83. PMID 23993308 DOI: 10.5414/Np300610  0.333
2014 Kamada M, Izumi Y, Ayaki T, Nakamura M, Kagawa S, Kudo E, Sako W, Maruyama H, Nishida Y, Kawakami H, Ito H, Kaji R. Clinicopathologic features of autosomal recessive amyotrophic lateral sclerosis associated with optineurin mutation. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 34: 64-70. PMID 23889540 DOI: 10.1111/Neup.12051  0.393
2014 Nakamura S, Wate R, Kaneko S, Ito H, Oki M, Tsuge A, Nagashima M, Asayama S, Fujita K, Nakamura M, Maruyama H, Kawakami H, Kusaka H. An autopsy case of sporadic amyotrophic lateral sclerosis associated with the I113T SOD1 mutation. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 34: 58-63. PMID 23773010 DOI: 10.1111/Neup.12049  0.611
2013 Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, ... ... Ito H, et al. Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Science Translational Medicine. 5: 188lr2. PMID 23740898 DOI: 10.1126/Scitranslmed.3005697  0.546
2013 Akizuki M, Yamashita H, Uemura K, Maruyama H, Kawakami H, Ito H, Takahashi R. Optineurin suppression causes neuronal cell death via NF-κB pathway. Journal of Neurochemistry. 126: 699-704. PMID 23721573 DOI: 10.1111/Jnc.12326  0.331
2013 Shodai A, Morimura T, Ido A, Uchida T, Ayaki T, Takahashi R, Kitazawa S, Suzuki S, Shirouzu M, Kigawa T, Muto Y, Yokoyama S, Takahashi R, Kitahara R, Ito H, et al. Aberrant assembly of RNA recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein of 43 kDa (TDP-43). The Journal of Biological Chemistry. 288: 14886-905. PMID 23558684 DOI: 10.1074/Jbc.M113.451849  0.563
2013 Matsui H, Sato F, Sato S, Koike M, Taruno Y, Saiki S, Funayama M, Ito H, Taniguchi Y, Uemura N, Toyoda A, Sakaki Y, Takeda S, Uchiyama Y, Hattori N, et al. ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons. Febs Letters. 587: 1316-25. PMID 23499937 DOI: 10.1016/J.Febslet.2013.02.046  0.359
2013 Matsui H, Gavinio R, Asano T, Uemura N, Ito H, Taniguchi Y, Kobayashi Y, Maki T, Shen J, Takeda S, Uemura K, Yamakado H, Takahashi R. PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates. Human Molecular Genetics. 22: 2423-34. PMID 23449626 DOI: 10.1093/Hmg/Ddt095  0.305
2013 Asayama S, Wate R, Kaneko S, Asayama T, Oki M, Tsuge A, Nagashima M, Morita J, Nakamura S, Nakamura M, Nishii M, Fujita K, Saito A, Nakano S, Ito H, et al. Levodopa challenge test and (123) I-metaiodobenzylguanidine scintigraphy for diagnosing Parkinson's disease. Acta Neurologica Scandinavica. 128: 160-5. PMID 23410225 DOI: 10.1111/Ane.12104  0.512
2013 Nakamura M, Kaneko S, Ito H, Jiang S, Fujita K, Wate R, Nakano S, Fujisawa J, Kusaka H. Activation of transforming growth factor-β/Smad signaling reduces aggregate formation of mislocalized TAR DNA-binding protein-43. Neuro-Degenerative Diseases. 11: 182-93. PMID 22797246 DOI: 10.1159/000338151  0.548
2013 Nakamura M, Kaneko S, Wate R, Asayama S, Nakamura Y, Fujita K, Ito H, Kusaka H. Regionally different immunoreactivity for Smurf2 and pSmad2/3 in TDP-43-positive inclusions of amyotrophic lateral sclerosis. Neuropathology and Applied Neurobiology. 39: 144-56. PMID 22435645 DOI: 10.1111/J.1365-2990.2012.01270.X  0.581
2013 Nakamura M, Kaneko S, Ito H, Jiang S, Fujita K, Wate R, Nakano S, Fujisawa J, Kusaka H, Flunkert S, Hierzer M, Löffler T, Rabl R, Neddens J, Duller S, et al. Contents Vol. 11, 2013 Neurodegenerative Diseases. 11. DOI: 10.1159/000350668  0.455
2012 Shodai A, Ido A, Fujiwara N, Ayaki T, Morimura T, Oono M, Uchida T, Takahashi R, Ito H, Urushitani M. Conserved acidic amino acid residues in a second RNA recognition motif regulate assembly and function of TDP-43. Plos One. 7: e52776. PMID 23300771 DOI: 10.1371/Journal.Pone.0052776  0.531
2012 Tashiro Y, Urushitani M, Inoue H, Koike M, Uchiyama Y, Komatsu M, Tanaka K, Yamazaki M, Abe M, Misawa H, Sakimura K, Ito H, Takahashi R. Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 287: 42984-94. PMID 23095749 DOI: 10.1074/Jbc.M112.417600  0.37
2012 Ishiura H, Sako W, Yoshida M, Kawarai T, Tanabe O, Goto J, Takahashi Y, Date H, Mitsui J, Ahsan B, Ichikawa Y, Iwata A, Yoshino H, Izumi Y, Fujita K, ... ... Ito H, et al. The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal dominant involvement. American Journal of Human Genetics. 91: 320-9. PMID 22883144 DOI: 10.1016/J.Ajhg.2012.07.014  0.588
2012 Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, ... ... Ito H, et al. Drug screening for ALS using patient-specific induced pluripotent stem cells. Science Translational Medicine. 4: 145ra104. PMID 22855461 DOI: 10.1126/Scitranslmed.3004052  0.604
2012 Sako W, Ito H, Yoshida M, Koizumi H, Kamada M, Fujita K, Hashizume Y, Izumi Y, Kaji R. Nuclear factor κ B expression in patients with sporadic amyotrophic lateral sclerosis and hereditary amyotrophic lateral sclerosis with optineurin mutations. Clinical Neuropathology. 31: 418-23. PMID 22762947 DOI: 10.5414/Np300493  0.503
2012 Honjo Y, Ito H, Horibe T, Shimada H, Nakanishi A, Mori H, Takahashi R, Kawakami K. Derlin-1-immunopositive inclusions in patients with Alzheimer's disease. Neuroreport. 23: 611-5. PMID 22627700 DOI: 10.1097/Wnr.0B013E3283552A75  0.324
2012 Kawamoto Y, Ito H, Ihara M, Takahashi R. Immunohistochemical localization of X-linked inhibitor of apoptosis protein in brainstem-type and cortical Lewy bodies. Neuroreport. 23: 162-7. PMID 22273571 DOI: 10.1097/Wnr.0B013E32834F4066  0.329
2012 Okamoto Y, Yamamoto T, Kalaria RN, Senzaki H, Maki T, Hase Y, Kitamura A, Washida K, Yamada M, Ito H, Tomimoto H, Takahashi R, Ihara M. Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts. Acta Neuropathologica. 123: 381-94. PMID 22170742 DOI: 10.1007/S00401-011-0925-9  0.579
2012 Kitamura A, Fujita Y, Oishi N, Kalaria RN, Washida K, Maki T, Okamoto Y, Hase Y, Yamada M, Takahashi J, Ito H, Tomimoto H, Fukuyama H, Takahashi R, Ihara M. Selective white matter abnormalities in a novel rat model of vascular dementia. Neurobiology of Aging. 33: 1012.e25-35. PMID 22133276 DOI: 10.1016/J.Neurobiolaging.2011.10.033  0.383
2012 Yamashita H, Fujimori N, Ito H, Iguchi Y, Atsuta N, Tanaka F, Sobue G, Takahashi R, Yamanaka K. Microarray Analysis in Spinal Cords of Sporadic ALS Patients with Cell-Type Specific Transcriptome (P05.168) Neurology. 78. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P05.168  0.364
2012 Nakamura M, Kaneko S, Ito H, Fujisawa J, Kusaka H. Activation of Transforming Growth Factor-beta/Smad Signaling Reduces Aggregate Formation of Mislocalized TAR DNA Binding Protein-43 (P03.182) Neurology. 78: P03.182-P03.182. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P03.182  0.52
2011 Okamoto Y, Ihara M, Urushitani M, Yamashita H, Kondo T, Tanigaki A, Oono M, Kawamata J, Ikemoto A, Kawamoto Y, Takahashi R, Ito H. An autopsy case of SOD1-related ALS with TDP-43 positive inclusions. Neurology. 77: 1993-5. PMID 22094482 DOI: 10.1212/Wnl.0B013E31823A0Cfc  0.68
2011 Honjo Y, Kaneko S, Ito H, Horibe T, Nagashima M, Nakamura M, Fujita K, Takahashi R, Kusaka H, Kawakami K. Protein disulfide isomerase-immunopositive inclusions in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 12: 444-50. PMID 21745122 DOI: 10.3109/17482968.2011.594055  0.602
2011 Honjo Y, Ito H, Horibe T, Takahashi R, Kawakami K. Protein disulfide isomerase immunopositive glial cytoplasmic inclusions in patients with multiple system atrophy. The International Journal of Neuroscience. 121: 543-50. PMID 21689057 DOI: 10.3109/00207454.2011.585440  0.339
2011 Okamoto Y, Shirakashi Y, Ihara M, Urushitani M, Oono M, Kawamoto Y, Yamashita H, Shimohama S, Kato S, Hirano A, Tomimoto H, Ito H, Takahashi R. Colocalization of 14-3-3 proteins with SOD1 in Lewy body-like hyaline inclusions in familial amyotrophic lateral sclerosis cases and the animal model. Plos One. 6: e20427. PMID 21655264 DOI: 10.1371/Journal.Pone.0020427  0.643
2011 Ito H, Nakamura M, Komure O, Ayaki T, Wate R, Maruyama H, Nakamura Y, Fujita K, Kaneko S, Okamoto Y, Ihara M, Konishi T, Ogasawara K, Hirano A, Kusaka H, et al. Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation. Acta Neuropathologica. 122: 223-9. PMID 21644038 DOI: 10.1007/S00401-011-0842-Y  0.692
2011 Ito H, Fujita K, Nakamura M, Wate R, Kaneko S, Sasaki S, Yamane K, Suzuki N, Aoki M, Shibata N, Togashi S, Kawata A, Mochizuki Y, Mizutani T, Maruyama H, et al. Optineurin is co-localized with FUS in basophilic inclusions of ALS with FUS mutation and in basophilic inclusion body disease. Acta Neuropathologica. 121: 555-7. PMID 21327942 DOI: 10.1007/S00401-011-0809-Z  0.746
2011 Nakamura M, Ito H, Nakamura Y, Wate R, Kaneko S, Nakano S, Matsumoto S, Kusaka H. Smad ubiquitination regulatory factor-2 in progressive supranuclear palsy. Neuropathology and Applied Neurobiology. 37: 307-14. PMID 20819168 DOI: 10.1111/J.1365-2990.2010.01120.X  0.561
2011 Saito S, Ozaki A, Takahashi M, Ito H, Matsumoto S, Tomimoto H. Clustering of multifocal cerebral infarctions in CADASIL: a case report. Journal of Neurology. 258: 325-7. PMID 20803343 DOI: 10.1007/S00415-010-5727-9  0.638
2011 Yamashita H, Fujimori N, Kataoka A, Iguchi Y, Atsuta N, Tanaka F, Sobue G, Ito H, Takahashi R, Yamanaka K. Microarray analysis in spinal cords of sporadic ALS patients with cell-type specific transcriptome Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.1276  0.341
2010 Matsui H, Ito H, Taniguchi Y, Takeda S, Takahashi R. Ammonium chloride and tunicamycin are novel toxins for dopaminergic neurons and induce Parkinson's disease-like phenotypes in medaka fish. Journal of Neurochemistry. 115: 1150-60. PMID 21219329 DOI: 10.1111/J.1471-4159.2010.07012.X  0.315
2010 Kawamoto Y, Ito H, Kobayashi Y, Suzuki Y, Takahashi R. Localization of HtrA2/Omi immunoreactivity in brains affected by Alzheimer's disease. Neuroreport. 21: 1121-5. PMID 20938363 DOI: 10.1097/Wnr.0B013E328340A731  0.327
2010 Matsui H, Ito H, Taniguchi Y, Inoue H, Takeda S, Takahashi R. Proteasome inhibition in medaka brain induces the features of Parkinson's disease. Journal of Neurochemistry. 115: 178-87. PMID 20649841 DOI: 10.1111/J.1471-4159.2010.06918.X  0.309
2010 Washida K, Ihara M, Nishio K, Fujita Y, Maki T, Yamada M, Takahashi J, Wu X, Kihara T, Ito H, Tomimoto H, Takahashi R. Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to peroxisome proliferator-activated receptor-gamma activation in mice with chronic cerebral hypoperfusion. Stroke; a Journal of Cerebral Circulation. 41: 1798-806. PMID 20595663 DOI: 10.1161/Strokeaha.110.583948  0.403
2010 Honjo Y, Ito H, Horibe T, Takahashi R, Kawakami K. Protein disulfide isomerase-immunopositive inclusions in patients with Alzheimer disease. Brain Research. 1349: 90-6. PMID 20550946 DOI: 10.1016/J.Brainres.2010.06.016  0.317
2010 Maruyama H, Morino H, Ito H, Izumi Y, Kato H, Watanabe Y, Kinoshita Y, Kamada M, Nodera H, Suzuki H, Komure O, Matsuura S, Kobatake K, Morimoto N, Abe K, et al. Mutations of optineurin in amyotrophic lateral sclerosis. Nature. 465: 223-6. PMID 20428114 DOI: 10.1038/Nature08971  0.725
2010 Kawamoto Y, Ito H, Kobayashi Y, Suzuki Y, Akiguchi I, Fujimura H, Sakoda S, Kusaka H, Hirano A, Takahashi R. HtrA2/Omi-immunoreactive intraneuronal inclusions in the anterior horn of patients with sporadic and Cu/Zn superoxide dismutase (SOD1) mutant amyotrophic lateral sclerosis. Neuropathology and Applied Neurobiology. 36: 331-44. PMID 20202124 DOI: 10.1111/J.1365-2990.2010.01075.X  0.69
2010 Washida K, Ihara M, Nishio K, Fujita Y, Maki T, Yamada M, Takahashi J, Wu X, Kihara T, Ito H, Tomimoto H, Takahashi R. Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to PPAR-γ activation in mice with chronic cerebral hypoperfusion Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.1342  0.381
2009 Kinoshita Y, Ito H, Hirano A, Fujita K, Wate R, Nakamura M, Kaneko S, Nakano S, Kusaka H. Nuclear contour irregularity and abnormal transporter protein distribution in anterior horn cells in amyotrophic lateral sclerosis. Journal of Neuropathology and Experimental Neurology. 68: 1184-92. PMID 19816199 DOI: 10.1097/Nen.0B013E3181Bc3Bec  0.66
2009 Ohnishi S, Ito H, Suzuki Y, Adachi Y, Wate R, Zhang J, Nakano S, Kusaka H, Ikehara S. Intra-bone marrow-bone marrow transplantation slows disease progression and prolongs survival in G93A mutant SOD1 transgenic mice, an animal model mouse for amyotrophic lateral sclerosis. Brain Research. 1296: 216-24. PMID 19686706 DOI: 10.1016/J.Brainres.2009.08.012  0.511
2009 Kamada M, Maruyama H, Tanaka E, Morino H, Wate R, Ito H, Kusaka H, Kawano Y, Miki T, Nodera H, Izumi Y, Kaji R, Kawakami H. Screening for TARDBP mutations in Japanese familial amyotrophic lateral sclerosis. Journal of the Neurological Sciences. 284: 69-71. PMID 19411082 DOI: 10.1016/J.Jns.2009.04.017  0.577
2009 Shinde A, Kunieda T, Kinoshita Y, Wate R, Nakano S, Ito H, Yamada M, Kitamoto T, Nakamura Y, Matsumoto S, Kusaka H. The first Japanese patient with variant Creutzfeldt-Jakob disease (vCJD). Neuropathology : Official Journal of the Japanese Society of Neuropathology. 29: 713-9. PMID 19389077 DOI: 10.1111/J.1440-1789.2009.01006.X  0.554
2009 Washida K, Ihara M, Takahashi J, Ito H, Tomimoto H, Takahashi R. The effect of vascular progenitor cells on chronic cerebral hypoperfusion mouse model Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.585  0.38
2008 Ito H, Wate R, Zhang J, Ohnishi S, Kaneko S, Ito H, Nakano S, Kusaka H. Treatment with edaravone, initiated at symptom onset, slows motor decline and decreases SOD1 deposition in ALS mice. Experimental Neurology. 213: 448-55. PMID 18718468 DOI: 10.1016/J.Expneurol.2008.07.017  0.566
2008 Fujita K, Ito H, Nakano S, Kinoshita Y, Wate R, Kusaka H. Immunohistochemical identification of messenger RNA-related proteins in basophilic inclusions of adult-onset atypical motor neuron disease. Acta Neuropathologica. 116: 439-45. PMID 18642007 DOI: 10.1007/S00401-008-0415-X  0.561
2008 Shinde A, Nakano S, Sugawara M, Toyoshima I, Ito H, Tanaka K, Kusaka H. Expression of caveolar components in primary desminopathy. Neuromuscular Disorders : Nmd. 18: 215-9. PMID 18343114 DOI: 10.1016/J.Nmd.2007.12.006  0.539
2008 Nakamura M, Ito H, Wate R, Nakano S, Hirano A, Kusaka H. Phosphorylated Smad2/3 immunoreactivity in sporadic and familial amyotrophic lateral sclerosis and its mouse model. Acta Neuropathologica. 115: 327-34. PMID 18210139 DOI: 10.1007/S00401-007-0337-Z  0.684
2008 Nakano S, Shinde A, Fujita K, Ito H, Kusaka H. Histone H1 is released from myonuclei and present in rimmed vacuoles with DNA in inclusion body myositis. Neuromuscular Disorders : Nmd. 18: 27-33. PMID 17888663 DOI: 10.1016/J.Nmd.2007.08.005  0.501
2007 Ito H, Ito H, Fujita K, Kinoshita Y, Takanashi Y, Kusaka H. Phrenic nerve conduction in the early stage of Guillain-Barre syndrome might predict the respiratory failure. Acta Neurologica Scandinavica. 116: 255-8. PMID 17824905 DOI: 10.1111/J.1600-0404.2007.00874.X  0.495
2007 Ito H, Ito H, Nakano S, Kusaka H. Low-dose subcutaneous injection of botulinum toxin type A for facial synkinesis and hyperlacrimation. Acta Neurologica Scandinavica. 115: 271-4. PMID 17376126 DOI: 10.1111/J.1600-0404.2006.00746.X  0.502
2006 Zhang J, Ito H, Wate R, Ohnishi S, Nakano S, Kusaka H. Altered distributions of nucleocytoplasmic transport-related proteins in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Acta Neuropathologica. 112: 673-80. PMID 16957927 DOI: 10.1007/S00401-006-0130-4  0.586
2006 Ito H, Ito H, Tanaka N, Asayama S, Nakano S, Kusaka H. [Bilateral gustatory disturbance associated with left putaminal hemorrhage]. Rinshå Shinkeigaku = Clinical Neurology. 46: 288-90. PMID 16768099  0.445
2005 Wate R, Ito H, Zhang JH, Ohnishi S, Nakano S, Kusaka H. Expression of an endoplasmic reticulum-resident chaperone, glucose-regulated stress protein 78, in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Acta Neuropathologica. 110: 557-62. PMID 16231159 DOI: 10.1007/S00401-005-1080-Y  0.581
2005 Nakano S, Shinde A, Ito H, Ito H, Kusaka H. Messenger RNA degradation may be inhibited in sporadic inclusion body myositis. Neurology. 65: 420-5. PMID 16087907 DOI: 10.1212/01.Wnl.0000171341.76482.15  0.519
2005 Fujita K, Nakano S, Yamamoto H, Ito H, Ito H, Goto Y, Kusaka H. [An adult case of congenital fiber type disproportion (CFTD) with cardiomyopathy]. Rinshå Shinkeigaku = Clinical Neurology. 45: 380-2. PMID 15960177  0.453
2005 Wate R, Takahashi S, Ito H, Kusaka H, Kubota Y, Suetomi K, Sato H, Okayasu R. Radio-sensitivity of the cells from amyotrophic lateral sclerosis model mice transfected with human mutant SOD1. Journal of Radiation Research. 46: 67-73. PMID 15802861 DOI: 10.1269/Jrr.46.67  0.557
2005 Ito H, Ito H, Nagano M, Nakano S, Shigeyoshi Y, Kusaka H. In situ identification of hepatitis C virus RNA in muscle. Neurology. 64: 1073-5. PMID 15781833 DOI: 10.1212/01.Wnl.0000154605.02737.Fe  0.48
2004 Ito H, Kusaka H. [Cognitive impairment induced by sedatives/hypnotics]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 62: 456-60. PMID 15011405  0.395
2003 Nakano S, Shinde A, Ito H, Ito H, Kusaka H. MAP kinase phosphatase-1 is induced in abnormal fibers in inclusion body myositis. Neurology. 61: 322-6. PMID 12913191 DOI: 10.1212/01.Wnl.0000076479.29079.10  0.5
2003 Tamaru Y, Nakashita M, Ito H, Okumura R, Matsumoto S, Imai T. Spontaneous remission of a massive CNS inflammation with eosinophilic infiltrate. Internal Medicine (Tokyo, Japan). 42: 424-7. PMID 12793714 DOI: 10.2169/Internalmedicine.42.424  0.461
2003 Ito H, Yoshika M, Ohnishi S, Iimuro R, Yagi A, Nakano S, Ito H, Kusaka H. [Intractable hiccups treated with mexiletine hydrochloride]. Nihon Naika Gakkai Zasshi. the Journal of the Japanese Society of Internal Medicine. 92: 316-7. PMID 12652738  0.409
2002 Ito H, Nakano S, Ito H, Kusaka H. Our Experience of Muscle Afferent Block for dystonia and spasticity The Journal of Kansai Medical University. 54: 130-134. DOI: 10.5361/Jkmu1956.54.2-4_130  0.471
1998 Tamaru Y, Hirano M, Ito H, Kawamura J, Matsumoto S, Imai T, Ueno S. Clinical similarities of hereditary progressive/dopa responsive dystonia caused by different types of mutations in the GTP cyclohydrolase I gene. Journal of Neurology, Neurosurgery, and Psychiatry. 64: 469-73. PMID 9576537 DOI: 10.1136/Jnnp.64.4.469  0.456
1998 Kobata H, Kondo A, Iwasaki K, Kusaka H, Ito H, Sawada S. Chordoid meningioma in a child. Case report. Journal of Neurosurgery. 88: 319-23. PMID 9452243 DOI: 10.3171/Jns.1998.88.2.0319  0.52
1997 Tamaru Y, Hirano M, Kusaka H, Ito H, Imai T, Ueno S. alpha-Tocopherol transfer protein gene: exon skipping of all transcripts causes ataxia. Neurology. 49: 584-8. PMID 9270601 DOI: 10.1212/Wnl.49.2.584  0.596
1997 Ii K, Ito H, Tanaka K, Hirano A. Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly. Journal of Neuropathology and Experimental Neurology. 56: 125-31. PMID 9034365 DOI: 10.1097/00005072-199702000-00002  0.536
1997 Hirano M, Tamaru Y, Ito H, Matsumoto S, Imai T, Ueno S. Mutant GTP cyclohydrolase I mRNA levels contribute to dopa-responsive dystonia onset. Annals of Neurology. 40: 796-8. PMID 8957022 DOI: 10.1002/Ana.410400517  0.479
1996 Ito H, Kusaka H, Matsumoto S, Imai T. Striatal efferent involvement and its correlation to levodopa efficacy in patients with multiple system atrophy. Neurology. 47: 1291-9. PMID 8909445 DOI: 10.1212/Wnl.47.5.1291  0.557
1996 Matsumoto S, Kusaka H, Ito H, Imai T. Golgi apparatus and intraneuronal inclusions of anterior horn cells in amyotrophic lateral sclerosis: an immunohistochemical study. Acta Neuropathologica. 91: 603-7. PMID 8781659 DOI: 10.1007/S004010050473  0.601
1996 Kaneko S, Ito H, Kusaka H, Imai T, Nishimura T, Yoshikawa H. Peripheral myelin protein-22 gene deletion in two unrelated Japanese pedigrees with hereditary neuropathy with liability to pressure palsies. Muscle & Nerve. 19: 675-6. PMID 8618572 DOI: 10.1002/mus.880190502  0.549
1995 Ito H, Kusaka H, Matsumoto S, Imai T. Topographic involvement of the striatal efferents in basal ganglia of patients with adult-onset motor neuron disease with basophilic inclusions. Acta Neuropathologica. 89: 513-8. PMID 7545858 DOI: 10.1007/Bf00571505  0.587
1994 Matsumoto S, Goto S, Kusaka H, Ito H, Imai T. Synaptic pathology of spinal anterior horn cells in amyotrophic lateral sclerosis: an immunohistochemical study. Journal of the Neurological Sciences. 125: 180-5. PMID 7807164 DOI: 10.1016/0022-510X(94)90032-9  0.686
1994 Ito H, Hirano A. Comparative study of spinal cord ubiquitin expression in post-poliomyelitis and sporadic amyotrophic lateral sclerosis. Acta Neuropathologica. 87: 425-9. PMID 7517092 DOI: 10.1007/Bf00313613  0.527
1993 Ito H, Goto S, Sakamoto S, Hirano A. Striosomal arrangement of met-enkephalin and substance P expression in parkinsonism-dementia complex on Guam. Acta Neuropathologica. 85: 390-3. PMID 7683167 DOI: 10.1007/Bf00334449  0.581
1992 Kato S, Hirano A, Llena JF, Ito H, Yen SH. Ultrastructural identification of neurofibrillary tangles in the spinal cords in Guamanian amyotrophic lateral sclerosis and parkinsonism-dementia complex on Guam. Acta Neuropathologica. 83: 277-82. PMID 1557958 DOI: 10.1007/Bf00296790  0.579
1992 Kusaka H, Imai T, Matsumoto S, Ito H, Yamasaki M. Myelination of two axons by a single Schwann cell. Acta Neuropathologica. 84: 574-6. PMID 1462770 DOI: 10.1007/BF00304478  0.417
1991 Kato S, Nakamura H, Hirano A, Ito H, Llena JF, Yen SH. Argyrophilic ubiquitinated cytoplasmic inclusions of Leu-7-positive glial cells in olivopontocerebellar atrophy (multiple system atrophy). Acta Neuropathologica. 82: 488-93. PMID 1723828 DOI: 10.1007/Bf00293383  0.63
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