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Neil W. Kowall, MD - Publications

Affiliations: 
Neurology and Pathology Boston University, Boston, MA, United States 
Area:
human neuroanatomy, immunocytochemistry and enzyme histochemistry of the brain, neuropathological basis of neurological disorders, animal models of neurological diseases, geriatric neurology, and cognitive decline in the elderly.
Website:
http://www.bu.edu/alzresearch/team/faculty/kowall.html

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, et al. Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30852157 DOI: 10.1016/j.jalz.2018.12.015  0.76
2019 Alosco ML, Tripodis Y, Rowland B, Chua AS, Liao H, Martin B, Jarnagin J, Chaisson CE, Pasternak O, Karmacharya S, Koerte IK, Cantu RC, Kowall NW, McKee AC, Shenton ME, et al. A magnetic resonance spectroscopy investigation in symptomatic former NFL players. Brain Imaging and Behavior. PMID 30848432 DOI: 10.1007/s11682-019-00060-4  0.76
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Kowall NW, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.76
2018 Cherry JD, Mez J, Crary JF, Tripodis Y, Alvarez VE, Mahar I, Huber BR, Alosco ML, Nicks R, Abdolmohammadi B, Kiernan PT, Evers L, Svirsky S, Babcock K, Gardner HM, ... ... Kowall NW, et al. Variation in TMEM106B in chronic traumatic encephalopathy. Acta Neuropathologica Communications. 6: 115. PMID 30390709 DOI: 10.1186/s40478-018-0619-9  0.76
2018 Walt GS, Burris HM, Brady CB, Spencer KR, Alvarez VE, Huber BR, Guilderson L, Abdul Rauf N, Collins D, Singh T, Mathias R, Averill JG, Walker SE, Robey I, McKee AC, ... Kowall NW, et al. Chronic Traumatic Encephalopathy Within an Amyotrophic Lateral Sclerosis Brain Bank Cohort. Journal of Neuropathology and Experimental Neurology. PMID 30299493 DOI: 10.1093/jnen/nly092  0.76
2018 Adams JW, Alvarez VE, Mez J, Huber BR, Tripodis Y, Xia W, Meng G, Kubilus CA, Cormier K, Kiernan PT, Daneshvar DH, Chua AS, Svirsky S, Nicks R, Abdolmohammadi B, ... ... Kowall NW, et al. Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports. Journal of Neuropathology and Experimental Neurology. PMID 30053297 DOI: 10.1093/jnen/nly065  0.76
2018 Alosco ML, Sugarman MA, Besser LM, Tripodis Y, Brett M, Palmisano JN, Kowall NW, Au R, Mez J, DeCarli C, Stein TD, McKee AC, Killiany RJ, Stern RA. A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology. Journal of Alzheimer's Disease : Jad. PMID 29843242 DOI: 10.3233/JAD-180017  0.76
2018 Alosco ML, Mez J, Tripodis Y, Kiernan PT, Abdolmohammadi B, Murphy L, Kowall NW, Stein TD, Huber BR, Goldstein LE, Cantu RC, Katz DI, Chaisson CE, Martin B, Solomon TM, et al. Age of First Exposure to Tackle Football and Chronic Traumatic Encephalopathy. Annals of Neurology. PMID 29710395 DOI: 10.1002/ana.25245  0.76
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Kowall NW, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/j.neuron.2018.02.027  0.36
2018 Tagge CA, Fisher AM, Minaeva OV, Gaudreau-Balderrama A, Moncaster JA, Zhang XL, Wojnarowicz MW, Casey N, Lu H, Kokiko-Cochran ON, Saman S, Ericsson M, Onos KD, Veksler R, Senatorov VV, ... ... Kowall NW, et al. Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model. Brain : a Journal of Neurology. PMID 29360998 DOI: 10.1093/brain/awx350  0.76
2017 Lee J, Kim Y, Liu T, Hwang YJ, Hyeon SJ, Im H, Lee K, Alvarez VE, McKee AC, Um SJ, Hur M, Mook-Jung I, Kowall NW, Ryu H. SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease. Aging Cell. PMID 29130578 DOI: 10.1111/acel.12679  0.76
2017 Friedman MJ, Huber BR, Brady CB, Ursano RJ, Benedek DM, Kowall NW, McKee AC. VA's National PTSD Brain Bank: a National Resource for Research. Current Psychiatry Reports. 19: 73. PMID 28840457 DOI: 10.1007/s11920-017-0822-6  0.76
2017 Mez J, Daneshvar DH, Kiernan PT, Abdolmohammadi B, Alvarez VE, Huber BR, Alosco ML, Solomon TM, Nowinski CJ, McHale L, Cormier KA, Kubilus CA, Martin BM, Murphy L, Baugh CM, ... ... Kowall NW, et al. Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football. Jama. 318: 360-370. PMID 28742910 DOI: 10.1001/jama.2017.8334  0.76
2017 Seo JS, Lee S, Shin JY, Hwang YJ, Cho H, Yoo SK, Kim Y, Lim S, Kim YK, Hwang EM, Kim SH, Kim CH, Hyeon SJ, Yun JY, Kim J, ... ... Kowall NW, et al. Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathy. Experimental & Molecular Medicine. 49: e333. PMID 28524178 DOI: 10.1038/emm.2017.56  0.76
2017 Alosco ML, Duskin J, Besser LM, Martin B, Chaisson CE, Gunstad J, Kowall NW, McKee AC, Stern RA, Tripodis Y. Modeling the Relationships Among Late-Life Body Mass Index, Cerebrovascular Disease, and Alzheimer's Disease Neuropathology in an Autopsy Sample of 1,421 Subjects from the National Alzheimer's Coordinating Center Data Set. Journal of Alzheimer's Disease : Jad. PMID 28304301 DOI: 10.3233/JAD-161205  0.76
2016 Rauh SP, Heymans MW, Mehr DR, Kruse RL, Lane P, Kowall NW, Volicer L, van der Steen JT. Predicting mortality in patients treated differently: updating and external validation of a prediction model for nursing home residents with dementia and lower respiratory infections. Bmj Open. 6: e011380. PMID 27577584 DOI: 10.1136/bmjopen-2016-011380  0.44
2016 Alosco ML, Mez J, Kowall NW, Stein TD, Goldstein LE, Cantu RC, Katz DI, Solomon TM, Kiernan PT, Murphy L, Abdolmohammadi B, Daneshvar D, Montenigro PH, Nowinski CJ, Stern RA, et al. Cognitive Reserve as a Modifier of Clinical Expression in Chronic Traumatic Encephalopathy: A Preliminary Examination. The Journal of Neuropsychiatry and Clinical Neurosciences. appineuropsych160300. PMID 27539377 DOI: 10.1176/appi.neuropsych.16030043  0.76
2015 Mez J, Solomon TM, Daneshvar DH, Murphy L, Kiernan PT, Montenigro PH, Kriegel J, Abdolmohammadi B, Fry B, Babcock KJ, Adams JW, Bourlas AP, Papadopoulos Z, McHale L, Ardaugh BM, ... ... Kowall NW, et al. Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study. Alzheimer's Research & Therapy. 7: 62. PMID 26455775 DOI: 10.1186/s13195-015-0148-8  0.76
2015 Stein TD, Montenigro PH, Alvarez VE, Xia W, Crary JF, Tripodis Y, Daneshvar DH, Mez J, Solomon T, Meng G, Kubilus CA, Cormier KA, Meng S, Babcock K, Kiernan P, ... ... Kowall NW, et al. Beta-amyloid deposition in chronic traumatic encephalopathy. Acta Neuropathologica. 130: 21-34. PMID 25943889 DOI: 10.1007/s00401-015-1435-y  0.76
2014 Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee da Y, Hong J, Kim HY, Oh SJ, ... ... Kowall NW, et al. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease. Nature Medicine. 20: 886-96. PMID 24973918 DOI: 10.1038/nm.3639  0.76
2014 Korkmaz OT, Aytan N, Carreras I, Choi JK, Kowall NW, Jenkins BG, Dedeoglu A. 7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis. Neuroscience Letters. 566: 286-91. PMID 24637017 DOI: 10.1016/j.neulet.2014.02.058  0.76
2014 Dysken MW, Sano M, Asthana S, Vertrees JE, Pallaki M, Llorente M, Love S, Schellenberg GD, McCarten JR, Malphurs J, Prieto S, Chen P, Loreck DJ, Trapp G, Bakshi RS, ... ... Kowall NW, et al. Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial. Jama. 311: 33-44. PMID 24381967 DOI: 10.1001/jama.2013.282834  0.76
2014 Kim KY, Hwang YJ, Jung MK, Choe J, Kim Y, Kim S, Lee CJ, Ahn H, Lee J, Kowall NW, Kim YK, Kim JI, Lee SB, Ryu H. A multifunctional protein EWS regulates the expression of Drosha and microRNAs. Cell Death and Differentiation. 21: 136-45. PMID 24185621 DOI: 10.1038/cdd.2013.144  0.76
2014 Lee J, Hwang YJ, Ryu H, Kowall NW, Ryu H. Nucleolar dysfunction in Huntington's disease. Biochimica Et Biophysica Acta. 1842: 785-90. PMID 24184605 DOI: 10.1016/j.bbadis.2013.09.017  0.76
2014 Dysken MW, Guarino PD, Vertrees JE, Asthana S, Sano M, Llorente M, Pallaki M, Love S, Schellenberg GD, McCarten JR, Malphurs J, Prieto S, Chen P, Loreck DJ, Carney S, ... ... Kowall NW, et al. Vitamin E and memantine in Alzheimer's disease: clinical trial methods and baseline data. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 36-44. PMID 23583234 DOI: 10.1016/j.jalz.2013.01.014  0.76
2013 Carreras I, McKee AC, Choi JK, Aytan N, Kowall NW, Jenkins BG, Dedeoglu A. R-flurbiprofen improves tau, but not Aß pathology in a triple transgenic model of Alzheimer's disease. Brain Research. 1541: 115-27. PMID 24161403 DOI: 10.1016/j.brainres.2013.10.025  0.76
2013 Aytan N, Choi JK, Carreras I, Kowall NW, Jenkins BG, Dedeoglu A. Combination therapy in a transgenic model of Alzheimer's disease. Experimental Neurology. 250: 228-38. PMID 24120437 DOI: 10.1016/j.expneurol.2013.10.001  0.76
2013 Brady CB, Trevor KT, Stein TD, Deykin EY, Perkins SD, Averill JG, Guilderson L, McKee AC, Renner SW, Kowall NW. The Department of Veterans Affairs Biorepository Brain Bank: a national resource for amyotrophic lateral sclerosis research. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 591-7. PMID 23971854 DOI: 10.3109/21678421.2013.822516  0.76
2013 Stern RA, Daneshvar DH, Baugh CM, Seichepine DR, Montenigro PH, Riley DO, Fritts NG, Stamm JM, Robbins CA, McHale L, Simkin I, Stein TD, Alvarez VE, Goldstein LE, Budson AE, ... Kowall NW, et al. Clinical presentation of chronic traumatic encephalopathy. Neurology. 81: 1122-9. PMID 23966253 DOI: 10.1212/WNL.0b013e3182a55f7f  0.76
2013 Lee JK, Shin JH, Hwang SG, Gwag BJ, McKee AC, Lee J, Kowall NW, Ryu H, Lim DS, Choi EJ. MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS. Proceedings of the National Academy of Sciences of the United States of America. 110: 12066-71. PMID 23818595 DOI: 10.1073/pnas.1300894110  0.76
2013 Lee J, Hwang YJ, Shin JY, Lee WC, Wie J, Kim KY, Lee MY, Hwang D, Ratan RR, Pae AN, Kowall NW, So I, Kim JI, Ryu H. Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone H3K9me3 impairs Ca(2+) signaling in Huntington's disease. Acta Neuropathologica. 125: 727-39. PMID 23455440 DOI: 10.1007/s00401-013-1103-z  0.76
2013 McKee AC, Stern RA, Nowinski CJ, Stein TD, Alvarez VE, Daneshvar DH, Lee HS, Wojtowicz SM, Hall G, Baugh CM, Riley DO, Kubilus CA, Cormier KA, Jacobs MA, Martin BR, ... ... Kowall NW, et al. The spectrum of disease in chronic traumatic encephalopathy. Brain : a Journal of Neurology. 136: 43-64. PMID 23208308 DOI: 10.1093/brain/aws307  0.76
2012 Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, ... ... Kowall NW, et al. Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model. Science Translational Medicine. 4: 134ra60. PMID 22593173 DOI: 10.1126/scitranslmed.3003716  0.76
2012 Butler D, Kowall NW, Lawler E, Michael Gaziano J, Driver JA. Underuse of diagnostic codes for specific dementias in the Veterans Affairs New England healthcare system. Journal of the American Geriatrics Society. 60: 910-5. PMID 22587853 DOI: 10.1111/j.1532-5415.2012.03933.x  0.76
2012 van der Steen JT, Lane P, Kowall NW, Knol DL, Volicer L. Antibiotics and mortality in patients with lower respiratory infection and advanced dementia. Journal of the American Medical Directors Association. 13: 156-61. PMID 21450193 DOI: 10.1016/j.jamda.2010.07.001  0.76
2011 Chopra MP, Trevino KM, Kowall NW. Memantine for posttraumatic stress disorder in an older veteran. Journal of Clinical Psychopharmacology. 31: 787-8. PMID 22051925 DOI: 10.1097/JCP.0b013e31823657bf  0.76
2011 Ryu H, Jeon GS, Cashman NR, Kowall NW, Lee J. Differential expression of c-Ret in motor neurons versus non-neuronal cells is linked to the pathogenesis of ALS. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 342-52. PMID 21283077 DOI: 10.1038/labinvest.2010.203  0.76
2011 Lee J, Kosaras B, Del Signore SJ, Cormier K, McKee A, Ratan RR, Kowall NW, Ryu H. Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice. Acta Neuropathologica. 121: 487-98. PMID 21161248 DOI: 10.1007/s00401-010-0788-5  0.76
2010 McKee AC, Gavett BE, Stern RA, Nowinski CJ, Cantu RC, Kowall NW, Perl DP, Hedley-Whyte ET, Price B, Sullivan C, Morin P, Lee HS, Kubilus CA, Daneshvar DH, Wulff M, et al. TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. Journal of Neuropathology and Experimental Neurology. 69: 918-29. PMID 20720505 DOI: 10.1097/NEN.0b013e3181ee7d85  0.76
2009 Lee J, Kannagi M, Ferrante RJ, Kowall NW, Ryu H. Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1739-49. PMID 19179380 DOI: 10.1096/fj.08-121046  0.76
2008 Yaar M, Arble BL, Stewart KB, Qureshi NH, Kowall NW, Gilchrest BA. p75NTR antagonistic cyclic peptide decreases the size of beta amyloid-induced brain inflammation. Cellular and Molecular Neurobiology. 28: 1027-31. PMID 18807174 DOI: 10.1007/s10571-008-9298-6  0.76
2008 Vlad SC, Miller DR, Kowall NW, Felson DT. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 70: 1672-7. PMID 18458226 DOI: 10.1212/01.wnl.0000311269.57716.63  0.76
2008 McKee AC, Carreras I, Hossain L, Ryu H, Klein WL, Oddo S, LaFerla FM, Jenkins BG, Kowall NW, Dedeoglu A. Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Research. 1207: 225-36. PMID 18374906 DOI: 10.1016/j.brainres.2008.01.095  0.76
2008 Hanlon EB, Perelman LT, Vitkin EI, Greco FA, McKee AC, Kowall NW. Scattering differentiates Alzheimer disease in vitro. Optics Letters. 33: 624-6. PMID 18347731 DOI: 10.1364/OL.33.000624  0.76
2007 Stack EC, Dedeoglu A, Smith KM, Cormier K, Kubilus JK, Bogdanov M, Matson WR, Yang L, Jenkins BG, Luthi-Carter R, Kowall NW, Hersch SM, Beal MF, Ferrante RJ. Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12908-15. PMID 18032664 DOI: 10.1523/JNEUROSCI.4318-07.2007  0.76
2007 Mellott TJ, Kowall NW, Lopez-Coviella I, Blusztajn JK. Prenatal choline deficiency increases choline transporter expression in the septum and hippocampus during postnatal development and in adulthood in rats. Brain Research. 1151: 1-11. PMID 17399691 DOI: 10.1016/j.brainres.2007.03.004  0.76
2006 Lee J, Kosaras B, Aleyasin H, Han JA, Park DS, Ratan RR, Kowall NW, Ferrante RJ, Lee SW, Ryu H. Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2375-7. PMID 17012241 DOI: 10.1096/fj.06-5957fje  0.76
2006 McKee AC, Au R, Cabral HJ, Kowall NW, Seshadri S, Kubilus CA, Drake J, Wolf PA. Visual association pathology in preclinical Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 621-30. PMID 16783172 DOI: 10.1097/00005072-200606000-00010  0.76
2006 Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW, Khrapko K. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nature Genetics. 38: 518-20. PMID 16604072 DOI: 10.1038/ng1778  0.76
2006 Klivenyi P, Siwek D, Gardian G, Yang L, Starkov A, Cleren C, Ferrante RJ, Kowall NW, Abeliovich A, Beal MF. Mice lacking alpha-synuclein are resistant to mitochondrial toxins. Neurobiology of Disease. 21: 541-8. PMID 16298531 DOI: 10.1016/j.nbd.2005.08.018  0.76
2004 Dedeoglu A, Cormier K, Payton S, Tseitlin KA, Kremsky JN, Lai L, Li X, Moir RD, Tanzi RE, Bush AI, Kowall NW, Rogers JT, Huang X. Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. Experimental Gerontology. 39: 1641-9. PMID 15582280 DOI: 10.1016/j.exger.2004.08.016  0.76
2003 Ferrante RJ, Kubilus JK, Lee J, Ryu H, Beesen A, Zucker B, Smith K, Kowall NW, Ratan RR, Luthi-Carter R, Hersch SM. Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9418-27. PMID 14561870  0.76
2003 McKeon-O'Malley C, Siwek D, Lamoureux JA, Williams CL, Kowall NW. Prenatal choline deficiency decreases the cross-sectional area of cholinergic neurons in the medial septal nucleus. Brain Research. 977: 278-83. PMID 12834888 DOI: 10.1016/S0006-8993(03)02599-X  0.76
2003 Albright CD, Siwek DF, Craciunescu CN, Mar MH, Kowall NW, Williams CL, Zeisel SH. Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutritional Neuroscience. 6: 129-34. PMID 12722989 DOI: 10.1080/1028415031000084418  0.76
2002 Dedeoglu A, Kubilus JK, Jeitner TM, Matson SA, Bogdanov M, Kowall NW, Matson WR, Cooper AJ, Ratan RR, Beal MF, Hersch SM, Ferrante RJ. Therapeutic effects of cystamine in a murine model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8942-50. PMID 12388601  0.76
2002 Kiechle T, Dedeoglu A, Kubilus J, Kowall NW, Beal MF, Friedlander RM, Hersch SM, Ferrante RJ. Cytochrome C and caspase-9 expression in Huntington's disease. Neuromolecular Medicine. 1: 183-95. PMID 12095160 DOI: 10.1385/NMM:1:3:183  0.76
2001 Malin DH, Crothers MK, Lake JR, Goyarzu P, Plotner RE, Garcia SA, Spell SH, Tomsic BJ, Giordano T, Kowall NW. Hippocampal injections of amyloid beta-peptide 1-40 impair subsequent one-trial/day reward learning. Neurobiology of Learning and Memory. 76: 125-37. PMID 11502145 DOI: 10.1006/nlme.2000.3991  0.76
2001 Andreassen OA, Ferrante RJ, Klivenyi P, Klein AM, Dedeoglu A, Albers DS, Kowall NW, Beal MF. Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid. Experimental Neurology. 168: 356-63. PMID 11259123 DOI: 10.1006/exnr.2001.7627  0.76
2000 Montine TJ, Shinobu L, Montine KS, Roberts LJ, Kowall NW, Beal MF, Morrow JD. No difference in plasma or urinary F2-isoprostanes among patients with Huntington's disease or Alzheimer's disease and controls. Annals of Neurology. 48: 950. PMID 11117557 DOI: 10.1002/1531-8249(200012)48:6<950::AID-ANA23>3.0.CO;2-F  0.76
2000 Kowall NW, Hantraye P, Brouillet E, Beal MF, McKee AC, Ferrante RJ. MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons. Neuroreport. 11: 211-3. PMID 10683860  0.76
2000 Simon DK, Mayeux R, Marder K, Kowall NW, Beal MF, Johns DR. Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease. Neurology. 54: 703-9. PMID 10680807  0.76
1999 Klein AM, Kowall NW, Ferrante RJ. Neurotoxicity and oxidative damage of beta amyloid 1-42 versus beta amyloid 1-40 in the mouse cerebral cortex. Annals of the New York Academy of Sciences. 893: 314-20. PMID 10672257  0.76
1999 Shefner JM, Reaume AG, Flood DG, Scott RW, Kowall NW, Ferrante RJ, Siwek DF, Upton-Rice M, Brown RH. Mice lacking cytosolic copper/zinc superoxide dismutase display a distinctive motor axonopathy. Neurology. 53: 1239-46. PMID 10522879  0.76
1999 Volicer L, Wells JM, McKee AC, Kowall NW. Enhanced inhibition of free radical-induced deoxyribose breakdown by Alzheimer brain homogenates. Neuroscience Letters. 270: 169-72. PMID 10462121 DOI: 10.1016/S0304-3940(99)00498-X  0.76
1999 Hanlon EB, Itzkan I, Dasari RR, Feld MS, Ferrante RJ, McKee AC, Lathi D, Kowall NW. Near-infrared fluorescence spectroscopy detects Alzheimer's disease in vitro. Photochemistry and Photobiology. 70: 236-42. PMID 10461462  0.76
1998 McKee AC, Kowall NW, Schumacher JS, Beal MF. The neurotoxicity of amyloid beta protein in aged primates. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 5: 1-9. PMID 9546999  0.76
1997 Beal MF, Ferrante RJ, Browne SE, Matthews RT, Kowall NW, Brown RH. Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Annals of Neurology. 42: 644-54. PMID 9382477 DOI: 10.1002/ana.410420416  0.76
1997 Ferrante RJ, Browne SE, Shinobu LA, Bowling AC, Baik MJ, MacGarvey U, Kowall NW, Brown RH, Beal MF. Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. Journal of Neurochemistry. 69: 2064-74. PMID 9349552  0.76
1997 Ferrante RJ, Shinobu LA, Schulz JB, Matthews RT, Thomas CE, Kowall NW, Gurney ME, Beal MF. Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation. Annals of Neurology. 42: 326-34. PMID 9307254 DOI: 10.1002/ana.410420309  0.76
1997 Ferrante RJ, Schulz JB, Kowall NW, Beal MF. Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra. Brain Research. 753: 157-62. PMID 9125443  0.68
1997 Ferrante RJ, Gutekunst CA, Persichetti F, McNeil SM, Kowall NW, Gusella JF, MacDonald ME, Beal MF, Hersch SM. Heterogeneous topographic and cellular distribution of huntingtin expression in the normal human neostriatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3052-63. PMID 9096140  0.76
1996 Speliotes EK, Kowall NW, Shanti BF, Kosofsky B, Finklestein SP, Leifer D. Myocyte-specific enhancer binding factor 2C expression in gerbil brain following global cerebral ischemia. Neuroscience. 70: 67-77. PMID 8848137  0.76
1996 Speliotes EK, Caday CG, Do T, Weise J, Kowall NW, Finklestein SP. Increased expression of basic fibroblast growth factor (bFGF) following focal cerebral infarction in the rat. Brain Research. Molecular Brain Research. 39: 31-42. PMID 8804711 DOI: 10.1016/0169-328X(95)00351-R  0.76
1996 Reaume AG, Elliott JL, Hoffman EK, Kowall NW, Ferrante RJ, Siwek DF, Wilcox HM, Flood DG, Beal MF, Brown RH, Scott RW, Snider WD. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nature Genetics. 13: 43-7. PMID 8673102 DOI: 10.1038/ng0596-43  0.76
1995 Schulz JB, Matthews RT, Jenkins BG, Ferrante RJ, Siwek D, Henshaw DR, Cipolloni PB, Mecocci P, Kowall NW, Rosen BR. Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 8419-29. PMID 8613773  0.76
1995 Schwagerl AL, Mohan PS, Cataldo AM, Vonsattel JP, Kowall NW, Nixon RA. Elevated levels of the endosomal-lysosomal proteinase cathepsin D in cerebrospinal fluid in Alzheimer disease. Journal of Neurochemistry. 64: 443-6. PMID 7798944  0.76
1995 Matsumoto K, Lo EH, Pierce AR, Wei H, Garrido L, Kowall NW. Role of vasogenic edema and tissue cavitation in ischemic evolution on diffusion-weighted imaging: comparison with multiparameter MR and immunohistochemistry. Ajnr. American Journal of Neuroradiology. 16: 1107-15. PMID 7639135  0.76
1995 Brouillet E, Hantraye P, Ferrante RJ, Dolan R, Leroy-Willig A, Kowall NW, Beal MF. Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates. Proceedings of the National Academy of Sciences of the United States of America. 92: 7105-9. PMID 7624378 DOI: 10.1073/pnas.92.15.7105  0.76
1995 Beal MF, Ferrante RJ, Henshaw R, Matthews RT, Chan PH, Kowall NW, Epstein CJ, Schulz JB. 3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice. Journal of Neurochemistry. 65: 919-22. PMID 7616254  0.76
1995 Schulz JB, Henshaw DR, Siwek D, Jenkins BG, Ferrante RJ, Cipolloni PB, Kowall NW, Rosen BR, Beal MF. Involvement of free radicals in excitotoxicity in vivo. Journal of Neurochemistry. 64: 2239-47. PMID 7536809  0.76
1995 Farrer LA, Abraham CR, Volicer L, Foley EJ, Kowall NW, McKee AC, Wells JM. Allele epsilon 4 of apolipoprotein E shows a dose effect on age at onset of Pick disease. Experimental Neurology. 136: 162-70. PMID 7498406 DOI: 10.1006/exnr.1995.1093  0.76
1994 Giordano T, Pan JB, Monteggia LM, Holzman TF, Snyder SW, Krafft G, Ghanbari H, Kowall NW. Similarities between beta amyloid peptides 1-40 and 40-1: effects on aggregation, toxicity in vitro, and injection in young and aged rats. Experimental Neurology. 125: 175-82. PMID 8313936 DOI: 10.1006/exnr.1994.1022  0.76
1994 Henshaw R, Jenkins BG, Schulz JB, Ferrante RJ, Kowall NW, Rosen BR, Beal MF. Malonate produces striatal lesions by indirect NMDA receptor activation. Brain Research. 647: 161-6. PMID 8069700  0.68
1994 Volicer L, Hurley AC, Lathi DC, Kowall NW. Measurement of severity in advanced Alzheimer's disease. Journal of Gerontology. 49: M223-6. PMID 8056941  0.76
1994 Schulz JB, Henshaw DR, Jenkins BG, Ferrante RJ, Kowall NW, Rosen BR, Beal MF. 3-Acetylpyridine produces age-dependent excitotoxic lesions in rat striatum. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 14: 1024-9. PMID 7929644 DOI: 10.1038/jcbfm.1994.134  0.68
1994 Storey E, Cipolloni PB, Ferrante RJ, Kowall NW, Beal MF. Movement disorder following excitotoxin lesions in primates. Neuroreport. 5: 1259-61. PMID 7919178  0.68
1993 Ferrante RJ, Kowall NW, Cipolloni PB, Storey E, Beal MF. Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neurochemical characterization. Experimental Neurology. 119: 46-71. PMID 8432351 DOI: 10.1006/exnr.1993.1006  0.68
1993 Kowall NW, McKee AC. The histopathology of neuronal degeneration and plasticity in Alzheimer disease. Advances in Neurology. 59: 5-33. PMID 8420123  0.76
1993 Brouillet E, Jenkins BG, Hyman BT, Ferrante RJ, Kowall NW, Srivastava R, Roy DS, Rosen BR, Beal MF. Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid. Journal of Neurochemistry. 60: 356-9. PMID 8417157  0.76
1993 Nihei K, McKee AC, Kowall NW. Patterns of neuronal degeneration in the motor cortex of amyotrophic lateral sclerosis patients. Acta Neuropathologica. 86: 55-64. PMID 8396837 DOI: 10.1007/BF00454899  0.76
1993 Markesbery WR, Wang HZ, Kowall NW, Kosik KS, McKee AC. Morphometric image analysis of neuropil threads in Alzheimer's disease. Neurobiology of Aging. 14: 303-7. PMID 8367011 DOI: 10.1016/0197-4580(93)90115-R  0.76
1993 Kowall NW, Quigley BJ, Krause JE, Lu F, Kosofsky BE, Ferrante RJ. Substance P and substance P receptor histochemistry in human neurodegenerative diseases. Regulatory Peptides. 46: 174-85. PMID 7692486 DOI: 10.1016/0167-0115(93)90028-7  0.76
1993 Beal MF, Brouillet E, Jenkins BG, Ferrante RJ, Kowall NW, Miller JM, Storey E, Srivastava R, Rosen BR, Hyman BT. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4181-92. PMID 7692009  0.76
1992 Yokota M, Peterson JW, Kaoutzanis M, Kowall NW. Immunohistochemical distribution of protein kinase C isozymes is differentially altered in ischemic gerbil hippocampus. Brain Research. 587: 123-9. PMID 1525642 DOI: 10.1016/0006-8993(92)91436-I  0.76
1992 Kowall NW, McKee AC, Yankner BA, Beal MF. In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment. Neurobiology of Aging. 13: 537-42. PMID 1461341 DOI: 10.1016/0197-4580(92)90053-Z  0.76
1992 Storey E, Kowall NW, Finn SF, Mazurek MF, Beal MF. The cortical lesion of Huntington's disease: further neurochemical characterization, and reproduction of some of the histological and neurochemical features by N-methyl-D-aspartate lesions of rat cortex. Annals of Neurology. 32: 526-34. PMID 1280937 DOI: 10.1002/ana.410320408  0.6
1991 McKee AC, Kosik KS, Kowall NW. Neuritic pathology and dementia in Alzheimer's disease. Annals of Neurology. 30: 156-65. PMID 1910274 DOI: 10.1002/ana.410300206  0.76
1991 Ferrante RJ, Kowall NW, Richardson EP. Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 3877-87. PMID 1836019  0.68
1991 Uemura Y, Kowall NW, Beal MF. Global ischemia induces NMDA receptor-mediated c-fos expression in neurons resistant to injury in gerbil hippocampus. Brain Research. 542: 343-7. PMID 1827611  0.6
1991 Wang LN, Kowall NW, Richardson EP. Phosphorylated neurofilament epitopes in the achromasic neurons of corticonigral degeneration. Chinese Medical Journal. 104: 1011-7. PMID 1782810  0.56
1991 Leifer D, Cole DG, Kowall NW. Neuropathologic asymmetries in the brain of a patient with a unilateral status epilepticus. Journal of the Neurological Sciences. 103: 127-35. PMID 1715386 DOI: 10.1016/0022-510X(91)90155-Z  0.76
1991 Kowall NW, Beal MF, Busciglio J, Duffy LK, Yankner BA. An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P. Proceedings of the National Academy of Sciences of the United States of America. 88: 7247-51. PMID 1714596  0.76
1991 Quigley BJ, Kowall NW. Substance P-like immunoreactive neurons are depleted in Alzheimer's disease cerebral cortex. Neuroscience. 41: 41-60. PMID 1711654 DOI: 10.1016/0306-4522(91)90199-X  0.76
1991 Beal MF, Ferrante RJ, Swartz KJ, Kowall NW. Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 1649-59. PMID 1710657  0.68
1991 Kowall NW, Beal MF. Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease. Annals of Neurology. 29: 162-7. PMID 1672808 DOI: 10.1002/ana.410290208  0.6
1991 Beal MF, Swartz KJ, Finn SF, Mazurek MF, Kowall NW. Neurochemical characterization of excitotoxin lesions in the cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 147-58. PMID 1670782  0.6
1990 McKee AC, Levine DN, Kowall NW, Richardson EP. Peduncular hallucinosis associated with isolated infarction of the substantia nigra pars reticulata. Annals of Neurology. 27: 500-4. PMID 2360791 DOI: 10.1002/ana.410270508  0.76
1990 McKee AC, Kosik KS, Kennedy MB, Kowall NW. Hippocampal neurons predisposed to neurofibrillary tangle formation are enriched in type II calcium/calmodulin-dependent protein kinase. Journal of Neuropathology and Experimental Neurology. 49: 49-63. PMID 2153760  0.76
1990 Uemura Y, Kowall NW, Beal MF. Selective sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum. Annals of Neurology. 27: 620-5. PMID 1972876 DOI: 10.1002/ana.410270606  0.6
1990 Beal MF, Kowall NW, Swartz KJ, Ferrante RJ. Homocysteic acid lesions in rat striatum spare somatostatin-neuropeptide Y (NADPH-diaphorase) neurons. Neuroscience Letters. 108: 36-42. PMID 1689475  0.68
1989 McKee AC, Kowall NW, Kosik KS. Microtubular reorganization and dendritic growth response in Alzheimer's disease. Annals of Neurology. 26: 652-9. PMID 2817839 DOI: 10.1002/ana.410260511  0.76
1989 Kowall NW, Pendlebury WW, Kessler JB, Perl DP, Beal MF. Aluminum-induced neurofibrillary degeneration affects a subset of neurons in rabbit cerebral cortex, basal forebrain and upper brainstem. Neuroscience. 29: 329-37. PMID 2725861 DOI: 10.1016/0306-4522(89)90060-2  0.76
1989 Beal MF, Mazurek MF, Ellison DW, Kowall NW, Solomon PR, Pendlebury WW. Neurochemical characteristics of aluminum-induced neurofibrillary degeneration in rabbits. Neuroscience. 29: 339-46. PMID 2566953 DOI: 10.1016/0306-4522(89)90061-4  0.76
1989 Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB. Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions. Synapse (New York, N.Y.). 3: 38-47. PMID 2563916 DOI: 10.1002/syn.890030106  0.68
1989 Kosik KS, Kowall NW, McKee A. Along the way to a neurofibrillary tangle: a look at the structure of tau. Annals of Medicine. 21: 109-12. PMID 2504256  0.44
1989 Kowall NW, Beal MF. Galanin-like immunoreactivity is present in human substantia innominata and in senile plaques in Alzheimer's disease. Neuroscience Letters. 98: 118-23. PMID 2469045  0.6
1988 Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB. Response:Model of Huntington's disease. Science (New York, N.Y.). 241: 475. PMID 17792612 DOI: 10.1126/science.241.4864.475  0.96
1988 Pendlebury WW, Beal MF, Kowall NW, Solomon PR. Neuropathologic, neurochemical and immunocytochemical characteristics of aluminum-induced neurofilamentous degeneration. Neurotoxicology. 9: 503-10. PMID 3200512  0.6
1988 Kowall NW, Beal MF. Cortical somatostatin, neuropeptide Y, and NADPH diaphorase neurons: normal anatomy and alterations in Alzheimer's disease. Annals of Neurology. 23: 105-14. PMID 2897822 DOI: 10.1002/ana.410230202  0.6
1988 Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB. Systemic approaches to modifying quinolinic acid striatal lesions in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 3901-8. PMID 2461437  0.68
1987 Kosik KS, Rogers J, Kowall NW. Senile plaques are located between apical dendritic clusters. Journal of Neuropathology and Experimental Neurology. 46: 1-11. PMID 3794758  0.44
1987 Ellison DW, Kowall NW, Martin JB. Subset of neurons characterized by the presence of NADPH-diaphorase in human substantia innominata. The Journal of Comparative Neurology. 260: 233-45. PMID 3611405 DOI: 10.1002/cne.902600207  0.76
1987 Pendlebury WW, Beal MF, Kowall NW, Solomon PR. Results of immunocytochemical, neurochemical, and behavioral studies in aluminum-induced neurofilamentous degeneration. Journal of Neural Transmission. Supplementum. 24: 213-7. PMID 3479524  0.6
1987 Kowall NW, Kosik KS. Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease. Annals of Neurology. 22: 639-43. PMID 3122646 DOI: 10.1002/ana.410220514  0.44
1987 Ferrante RJ, Beal MF, Kowall NW, Richardson EP, Martin JB. Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease. Brain Research. 411: 162-6. PMID 2955849  0.68
1987 Ferrante RJ, Kowall NW, Beal MF, Martin JB, Bird ED, Richardson EP. Morphologic and histochemical characteristics of a spared subset of striatal neurons in Huntington's disease. Journal of Neuropathology and Experimental Neurology. 46: 12-27. PMID 2947977  0.68
1987 Ferrante RJ, Kowall NW. Tyrosine hydroxylase-like immunoreactivity is distributed in the matrix compartment of normal human and Huntington's disease striatum. Brain Research. 416: 141-6. PMID 2887244  0.68
1987 Kowall NW, Ferrante RJ, Beal MF, Richardson EP, Sofroniew MV, Cuello AC, Martin JB. Neuropeptide Y, somatostatin, and reduced nicotinamide adenine dinucleotide phosphate diaphorase in the human striatum: a combined immunocytochemical and enzyme histochemical study. Neuroscience. 20: 817-28. PMID 2885780 DOI: 10.1016/0306-4522(87)90242-9  0.76
1987 Beal MF, Kowall NW, Mazurek MF. Neuropeptides in Alzheimer's disease. Journal of Neural Transmission. Supplementum. 24: 163-74. PMID 2445913  0.6
1986 Ferrante RJ, Kowall NW, Richardson EP, Bird ED, Martin JB. Topography of enkephalin, substance P and acetylcholinesterase staining in Huntington's disease striatum. Neuroscience Letters. 71: 283-8. PMID 2432445  0.68
1986 Haber SN, Kowall NW, Vonsattel JP, Bird ED, Richardson EP. Gilles de la Tourette's syndrome. A postmortem neuropathological and immunohistochemical study. Journal of the Neurological Sciences. 75: 225-41. PMID 2428943  0.56
1986 Groenewegen HJ, Ahlenius S, Haber SN, Kowall NW, Nauta WJ. Cytoarchitecture, fiber connections, and some histochemical aspects of the interpeduncular nucleus in the rat. The Journal of Comparative Neurology. 249: 65-102. PMID 2426312 DOI: 10.1002/cne.902490107  0.76
1986 Beal MF, Kowall NW, Ellison DW, Mazurek MF, Swartz KJ, Martin JB. Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature. 321: 168-71. PMID 2422561 DOI: 10.1038/321168a0  0.76
1985 Ferrante RJ, Kowall NW, Beal MF, Richardson EP, Bird ED, Martin JB. Selective sparing of a class of striatal neurons in Huntington's disease. Science (New York, N.Y.). 230: 561-3. PMID 2931802  0.68
1985 Kowall NW, Beal MF, Ferrante RJ, Martin JB. Topography of nicotinamide adenine dinucleotide phosphate-diaphorase staining neurons in rat striatum. Neuroscience Letters. 59: 61-6. PMID 2931630  0.68
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